|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
1-468 |
5.28e-88 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 274.34 E-value: 5.28e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqesee 80
Cdd:COG0471 6 LAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL---------------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 81 ntaavrrnglhtvptemqflasteakdhpgetevpldlpadsrkEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLI 160
Cdd:COG0471 70 --------------------------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLI 105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 161 LLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwRKNKSEIrtnaeDRARAVIREEYQNLGPI 240
Cdd:COG0471 106 AAGLLEEATGI--PISFFEWMLVGLPVALVGLLLLWLVLYRLL--------PPEIKEV-----PGSKEVIREELAELGPL 170
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 241 KFAEQAVFILFCMFAILLFTRDPKFIPgwaslfnpgflsDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTW 320
Cdd:COG0471 171 SRREKIALAIFALTVLLWITGSLHGIP------------IAVVALLGAVLLLLTG---------------------VLTW 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 321 KKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAE 399
Cdd:COG0471 218 KDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALlPLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAIS 297
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301069353 400 LAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 468
Cdd:COG0471 298 LAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
2-460 |
3.84e-57 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 194.73 E-value: 3.84e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 2 ASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqeseen 81
Cdd:cd01115 59 GAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKL----------------- 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 82 taavrrnglhtvPTEMQFLasteakdhpgetevpldlpadsrkedeyrrniwkgfLISIPYSASIGGTATLTGTAPNLIL 161
Cdd:cd01115 122 ------------DISPSRL------------------------------------LMPLAFAASIGGMLTLIGTPPNLVA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 162 LGQLKSFFPQcdvvnfGSWFIFAFPLMLLFLLAGWLWISFLYGglsfrgwrknkseirtnaedraravireeyqnlgpik 241
Cdd:cd01115 154 SGYLESLGGQ------GFSFFEFTPIGLPLLIIGLLYLWFIFR------------------------------------- 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 242 faeqavfILFCMFAILLFTrdpkfipgwASLFNPGFLSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWK 321
Cdd:cd01115 191 -------LAVLIITIVLLA---------ALAAITGLLPVSVAIAIGAIVLVFGG---------------------VLLTK 233
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 322 KAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHP-LENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL 400
Cdd:cd01115 234 EDYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSI 313
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 401 AIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLL 460
Cdd:cd01115 314 ALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVV 373
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
2-468 |
7.37e-53 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 185.65 E-value: 7.37e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 2 ASAIEEWNLHRRIALKILMLVGVQParLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL---FGqkevrkdpsqes 78
Cdd:pfam00939 96 SAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLppaFG------------ 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 79 eentaavrrnglhtvptemqflasteakdhpgetevpldlpadSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPN 158
Cdd:pfam00939 162 -------------------------------------------SDPEKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPN 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 159 LILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGwrknkseirtnaeDRARAVIREEYQNLG 238
Cdd:pfam00939 199 LLLLGLMNSILGV--TITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSV-------------PDAKAIAKTELKELG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 239 PIKFAEQAVFILFCMFAILLFTRDPKFIpgwaslfnpgflSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLL 318
Cdd:pfam00939 264 PMTFREKALLGLFVLLLLLWIFGGSLNI------------DATTVAIIGLALMLLLR---------------------IL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 319 TWKKA-QETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPL--ENVPPALAVLLITVVIAFFTEFASNTATIIIFLP 395
Cdd:pfam00939 311 DWKDIvKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLP 390
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301069353 396 VLAELAIRLRVHP-LYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 468
Cdd:pfam00939 391 IFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWW 465
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
1-469 |
2.79e-46 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 167.14 E-value: 2.79e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKILMLVGVQPARL-ILGMMVTTSFLSMWLSNTA-STAMMLPIANAILkslfgqkevrkdpsqes 78
Cdd:TIGR00785 75 LATALVKTGLGKRIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLL----------------- 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 79 eentaavrrnglhtvptemqflasteakdhpgetevpldlPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPN 158
Cdd:TIGR00785 138 ----------------------------------------PLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 159 LILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwrknKSEIRTNaeDRARAVIREEYQNLG 238
Cdd:TIGR00785 178 ALAAGILSKILGI--QISWGDWFLAGLPLGIILLLLVPLLLYVLF-----------PPELKLK--DEVDLWAKEELEEMG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 239 PIKFAEQAVFILFcMFAILLFtrdpkfipgwasLFNPGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapntetepLL 318
Cdd:TIGR00785 243 PMSFREKALLGIF-LLALLLW------------IFGGSLGINASVVALLAVVLMLFLG--------------------IV 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 319 TWKKAQE-TVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFF-TEFASNTATIIIFLP 395
Cdd:TIGR00785 290 TWKDIQKnKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLvGILDGLSPTIAVLVLVVLFYIIlYFFASNTAHTAALVP 369
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301069353 396 VLAELAIRLRVHPLYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWA 469
Cdd:TIGR00785 370 IFFSVASAQGIPLELLALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLWW 444
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
1-468 |
5.28e-88 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 274.34 E-value: 5.28e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqesee 80
Cdd:COG0471 6 LAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL---------------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 81 ntaavrrnglhtvptemqflasteakdhpgetevpldlpadsrkEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLI 160
Cdd:COG0471 70 --------------------------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGTPPNLI 105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 161 LLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwRKNKSEIrtnaeDRARAVIREEYQNLGPI 240
Cdd:COG0471 106 AAGLLEEATGI--PISFFEWMLVGLPVALVGLLLLWLVLYRLL--------PPEIKEV-----PGSKEVIREELAELGPL 170
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 241 KFAEQAVFILFCMFAILLFTRDPKFIPgwaslfnpgflsDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTW 320
Cdd:COG0471 171 SRREKIALAIFALTVLLWITGSLHGIP------------IAVVALLGAVLLLLTG---------------------VLTW 217
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 321 KKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAE 399
Cdd:COG0471 218 KDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALlPLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAIS 297
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301069353 400 LAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 468
Cdd:COG0471 298 LAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
2-460 |
3.84e-57 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 194.73 E-value: 3.84e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 2 ASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqeseen 81
Cdd:cd01115 59 GAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKL----------------- 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 82 taavrrnglhtvPTEMQFLasteakdhpgetevpldlpadsrkedeyrrniwkgfLISIPYSASIGGTATLTGTAPNLIL 161
Cdd:cd01115 122 ------------DISPSRL------------------------------------LMPLAFAASIGGMLTLIGTPPNLVA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 162 LGQLKSFFPQcdvvnfGSWFIFAFPLMLLFLLAGWLWISFLYGglsfrgwrknkseirtnaedraravireeyqnlgpik 241
Cdd:cd01115 154 SGYLESLGGQ------GFSFFEFTPIGLPLLIIGLLYLWFIFR------------------------------------- 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 242 faeqavfILFCMFAILLFTrdpkfipgwASLFNPGFLSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWK 321
Cdd:cd01115 191 -------LAVLIITIVLLA---------ALAAITGLLPVSVAIAIGAIVLVFGG---------------------VLLTK 233
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 322 KAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHP-LENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL 400
Cdd:cd01115 234 EDYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSI 313
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 401 AIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLL 460
Cdd:cd01115 314 ALSLGLPPEALLLAVAIGASCAFMLPVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVV 373
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
2-468 |
7.37e-53 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 185.65 E-value: 7.37e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 2 ASAIEEWNLHRRIALKILMLVGVQParLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL---FGqkevrkdpsqes 78
Cdd:pfam00939 96 SAAFEKTGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLppaFG------------ 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 79 eentaavrrnglhtvptemqflasteakdhpgetevpldlpadSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPN 158
Cdd:pfam00939 162 -------------------------------------------SDPEKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPN 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 159 LILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGwrknkseirtnaeDRARAVIREEYQNLG 238
Cdd:pfam00939 199 LLLLGLMNSILGV--TITWASWFLAAIPPGVILLLLAPLLLYVLYPPEIKSV-------------PDAKAIAKTELKELG 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 239 PIKFAEQAVFILFCMFAILLFTRDPKFIpgwaslfnpgflSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLL 318
Cdd:pfam00939 264 PMTFREKALLGLFVLLLLLWIFGGSLNI------------DATTVAIIGLALMLLLR---------------------IL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 319 TWKKA-QETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPL--ENVPPALAVLLITVVIAFFTEFASNTATIIIFLP 395
Cdd:pfam00939 311 DWKDIvKNKGAWNTLIWLGGLIMLANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLP 390
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301069353 396 VLAELAIRLRVHP-LYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 468
Cdd:pfam00939 391 IFAAVAQAIPGAPpLLAALLLGFAISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWW 465
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
1-469 |
2.79e-46 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 167.14 E-value: 2.79e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKILMLVGVQPARL-ILGMMVTTSFLSMWLSNTA-STAMMLPIANAILkslfgqkevrkdpsqes 78
Cdd:TIGR00785 75 LATALVKTGLGKRIAYKLVGKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLL----------------- 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 79 eentaavrrnglhtvptemqflasteakdhpgetevpldlPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPN 158
Cdd:TIGR00785 138 ----------------------------------------PLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 159 LILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwrknKSEIRTNaeDRARAVIREEYQNLG 238
Cdd:TIGR00785 178 ALAAGILSKILGI--QISWGDWFLAGLPLGIILLLLVPLLLYVLF-----------PPELKLK--DEVDLWAKEELEEMG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 239 PIKFAEQAVFILFcMFAILLFtrdpkfipgwasLFNPGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapntetepLL 318
Cdd:TIGR00785 243 PMSFREKALLGIF-LLALLLW------------IFGGSLGINASVVALLAVVLMLFLG--------------------IV 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 319 TWKKAQE-TVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFF-TEFASNTATIIIFLP 395
Cdd:TIGR00785 290 TWKDIQKnKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLvGILDGLSPTIAVLVLVVLFYIIlYFFASNTAHTAALVP 369
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 301069353 396 VLAELAIRLRVHPLYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWA 469
Cdd:TIGR00785 370 IFFSVASAQGIPLELLALALALSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLWW 444
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
1-465 |
1.12e-34 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 134.30 E-value: 1.12e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKIlMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKslfgqkevrkdpsqesee 80
Cdd:cd00625 51 LSAALEETGLFDRLAAKL-ARASKGSRRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLR------------------ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 81 ntaavRRNGLHTVPtemqflasteakdhpgetevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLI 160
Cdd:cd00625 112 -----KLGLSPPVP-----------------------------------------LLLALAFAANIGGAATPIGNPPNLI 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 161 LLGQLKsffpqcdvVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGlsfrgwrknksEIRTNAEDRARAVIREEYQNLGPI 240
Cdd:cd00625 146 IASLSG--------LGFLDFLAFMAPPALGLLLLLLGLLYLLFRK-----------KLLLPDEDKLTVLAEPLPARPLLK 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 241 KFAEQAVFILFCMFAILLFTRDPKFIpgwaslfnpgflsdAVTGVAIVTILFFFpsqrpslkwwfdfkapntetepLLTW 320
Cdd:cd00625 207 KFLLLALLLLLLFVLLFFFLIPLGLI--------------ALLGALLLLLLLVR----------------------GLDP 250
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 321 KKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL 400
Cdd:cd00625 251 EEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASL 330
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 401 -----AIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAfasgHLLVKDMVRTGLLMNLMgVLLLSLAM 465
Cdd:cd00625 331 appepAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGV----GISFGEFLKVGLPLTLL-SLVVSLLY 395
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
1-401 |
6.81e-24 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 102.39 E-value: 6.81e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslfgqkevrkdpsqesee 80
Cdd:pfam03600 51 IGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIMIPIVLAL-------------------- 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 81 ntaaVRRNGLHTVPtemqflasteakdhpgetevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLI 160
Cdd:pfam03600 111 ----ARRLGLPPSP-----------------------------------------LLIALAFAANIGGTATPIGDPPNII 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 161 LLGQLKsffpqcdvVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIreeyqnlgpi 240
Cdd:pfam03600 146 IASALG--------LSFGDFGFFMFPPVGVALLLVGLLPLLLIFRKLLPVRKEEEAELEELRKRAIKDKL---------- 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 241 kfaeqAVFILFCMFAILLFtrdpkfipgwaslfnpGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapnteteplLTW 320
Cdd:pfam03600 208 -----LLAISALVLALVIL----------------GFLLLSVLALAGALLLLLTGV---------------------LDP 245
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 321 KKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLenVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL 400
Cdd:pfam03600 246 EEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGL--SGLLVALALILWLSALLSAFISNVPTAALMAPIIVGM 323
|
.
gi 301069353 401 A 401
Cdd:pfam03600 324 A 324
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
316-465 |
1.34e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 62.71 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 316 PLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLP 395
Cdd:pfam03600 26 GVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIMIP 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 301069353 396 VLAELAIRLRVHPLYLMIPGTVGCSFAFML-PVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAM 465
Cdd:pfam03600 106 IVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP 176
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
1-413 |
1.96e-09 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 59.37 E-value: 1.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 1 MASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslfgqkevrkdpsqesee 80
Cdd:COG1055 65 IVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAI-------------------- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 81 ntaaVRRNGLHTVPtemqflasteakdhpgetevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLI 160
Cdd:COG1055 125 ----ARRLGLNPVP-----------------------------------------FLIAIVFAANIGGAATPIGNPTNIM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 161 LLGQLKsffpqcdvVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGlSFRGWRKNKSEIRTNAEDRARAVIreeyqnlgpi 240
Cdd:COG1055 160 IASAGG--------LSFLDFLANLFPPSLVSLLVTLLVLYLLFRK-ELPAAPDLEDDPKEAIKDRRLLRI---------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 241 kfaeqAVFILFCMFAILLFTRDPKFIPGWASLFnpgflsdavtgVAIVTILFffpsqrpslkwwfdfkapnTETEPLLTW 320
Cdd:COG1055 221 -----SLLVLALLLVGFVLHSFLGLPPALIALL-----------GAAVLLLL-------------------ARVDVREVL 265
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 321 KKaqetVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL 400
Cdd:COG1055 266 KK----VDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDL 341
|
410
....*....|...
gi 301069353 401 AIRLRVHPLYLMI 413
Cdd:COG1055 342 GATGNPEPLWLAL 354
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
317-461 |
2.88e-09 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 58.80 E-value: 2.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 317 LLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALaVLLITVVIAFFTEFASNTATIIIFLPV 396
Cdd:cd00625 27 VVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRL-LLLLMLLTAALSAFFSNDATAVLLTPI 105
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 301069353 397 LAELAIRLR-VHPLYLMIPGTVGCSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLL 461
Cdd:cd00625 106 VLALLRKLGlSPPVPLLLALAFAANIGgAATPIGNPPNLIIASLSGLGFLDFLAFMAPPALGLLLLL 172
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
317-441 |
2.44e-08 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 55.90 E-value: 2.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 317 LLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPV 396
Cdd:COG1055 41 VVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPV 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 301069353 397 LAELAIRLRVHPLYLMIpgtvGCSFA-----FMLPVSTPPNSIAFASGHL 441
Cdd:COG1055 121 VLAIARRLGLNPVPFLI----AIVFAaniggAATPIGNPTNIMIASAGGL 166
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
330-435 |
5.00e-07 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 51.82 E-value: 5.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 330 NIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPL 409
Cdd:cd01115 47 PAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPS 126
|
90 100
....*....|....*....|....*..
gi 301069353 410 YLMIPGTVGCSFAFML-PVSTPPNSIA 435
Cdd:cd01115 127 RLLMPLAFAASIGGMLtLIGTPPNLVA 153
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
136-422 |
9.04e-07 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 51.10 E-value: 9.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 136 FLISIPYSASIGGTATLTGTAPNLILlgqlksffPQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGglsfRGWRKNK 215
Cdd:cd01116 129 VLISEVIAANIGGAATLIGDPPNIMI--------GSAAGLTFNDFLLHMLPSVVLALVVTFILLYFLYR----NILKARE 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 216 SEIRTNAEDRARAVIREeyqnlgpIKFAEQAVFILFCMFAILLFTRDPKFIPGWaslfnpgflsdaVTGVAIVTILFFFP 295
Cdd:cd01116 197 EDVLALAELEPKYPIKD-------KVLLLKSLTILTLVIIGFVLHSPLGVSLGW------------IALLGALLLLLLAD 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 296 sqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITV 375
Cdd:cd01116 258 ---------------------KLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILW 316
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 301069353 376 VIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFA 422
Cdd:cd01116 317 ISALLSAFIDNIPVTATMIPIVKDLASQLGIPLLPLWWALALGACLG 363
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
337-435 |
1.17e-06 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 50.54 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 337 GGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVH-----PLYL 411
Cdd:COG0471 2 GGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEkrskfGSAL 81
|
90 100
....*....|....*....|....*
gi 301069353 412 MIPGTVGCSF-AFMLPVSTPPNSIA 435
Cdd:COG0471 82 LLPIAFAASIgGMGTLIGTPPNLIA 106
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
142-203 |
1.28e-04 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 44.35 E-value: 1.28e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 301069353 142 YSASIGGTATLTGTAPNLILLGQLKSffpQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLY 203
Cdd:COG1055 356 LGATLGGNLTPIGSAANVIVLGIAEK---KGIKISFGEFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
329-441 |
1.56e-03 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 40.71 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 301069353 329 WNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHP 408
Cdd:cd01118 52 WDVTLTLIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKK 131
|
90 100 110
....*....|....*....|....*....|....*..
gi 301069353 409 L----YLMIPGTVGCSFAFMLPVSTPPNSIAFASGHL 441
Cdd:cd01118 132 NrtlpFLYACAFIADAASLPLPISNLVNIVTAGYFGI 168
|
|
| |
