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Conserved domains on  [gi|296317276|ref|NP_001171737|]
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CD99 antigen-like protein 2 isoform 4 precursor [Homo sapiens]

Protein Classification

CD99L2 domain-containing protein( domain architecture ID 10574149)

CD99L2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CD99L2 pfam12301
CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this ...
 30-166 2.12e-55

CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.


:

Pssm-ID: 463526  Cd Length: 162  Bit Score: 172.70  E-value: 2.12e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317276   30 FNLEDAVKETSSVKQPWDHTTTTTTNRPGTtRAPAKPPGS----GLDLADALDDQDDGRRKPGIGGR------------- 92
Cdd:pfam12301   1 FDLADALDETSPPPQKPDVTTTTTKRPKTT-KKPAKPKPDdfdlSDALDPENDIPGKGPNKGGSGGGgfsdddledvaeg 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317276   93 ---------GDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVC 163
Cdd:pfam12301  80 ggykpdkgkGGGRGGSNDDGGSDQPAETGTIAGIVSAVAMALLGAVSSYISYQKKKLCFSIQQGLNAEYVKGENLEAVVA 159


                  ...
gi 296317276  164 EEP 166
Cdd:pfam12301 160 EEP 162
 
Name Accession Description Interval E-value
CD99L2 pfam12301
CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this ...
 30-166 2.12e-55

CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.


Pssm-ID: 463526  Cd Length: 162  Bit Score: 172.70  E-value: 2.12e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317276   30 FNLEDAVKETSSVKQPWDHTTTTTTNRPGTtRAPAKPPGS----GLDLADALDDQDDGRRKPGIGGR------------- 92
Cdd:pfam12301   1 FDLADALDETSPPPQKPDVTTTTTKRPKTT-KKPAKPKPDdfdlSDALDPENDIPGKGPNKGGSGGGgfsdddledvaeg 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317276   93 ---------GDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVC 163
Cdd:pfam12301  80 ggykpdkgkGGGRGGSNDDGGSDQPAETGTIAGIVSAVAMALLGAVSSYISYQKKKLCFSIQQGLNAEYVKGENLEAVVA 159


                  ...
gi 296317276  164 EEP 166
Cdd:pfam12301 160 EEP 162
 
Name Accession Description Interval E-value
CD99L2 pfam12301
CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this ...
 30-166 2.12e-55

CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.


Pssm-ID: 463526  Cd Length: 162  Bit Score: 172.70  E-value: 2.12e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317276   30 FNLEDAVKETSSVKQPWDHTTTTTTNRPGTtRAPAKPPGS----GLDLADALDDQDDGRRKPGIGGR------------- 92
Cdd:pfam12301   1 FDLADALDETSPPPQKPDVTTTTTKRPKTT-KKPAKPKPDdfdlSDALDPENDIPGKGPNKGGSGGGgfsdddledvaeg 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 296317276   93 ---------GDGRYGSNDDPGSGMVAEPGTIAGVASALAMALIGAVSSYISYQQKKFCFSIQQGLNADYVKGENLEAVVC 163
Cdd:pfam12301  80 ggykpdkgkGGGRGGSNDDGGSDQPAETGTIAGIVSAVAMALLGAVSSYISYQKKKLCFSIQQGLNAEYVKGENLEAVVA 159


                  ...
gi 296317276  164 EEP 166
Cdd:pfam12301 160 EEP 162
ACT_7 pfam13840
ACT domain; The ACT domain is a structural motif of 70-90 amino acids that functions in the ...
 104-162 9.01e-03

ACT domain; The ACT domain is a structural motif of 70-90 amino acids that functions in the control of metabolism, solute transport and signal transduction. They are thus found in a variety of different proteins in a variety of different arrangements. In mammalian phenylalanine hydroxylase the domain forms no contacts but promotes an allosteric effect despite the apparent lack of ligand binding.


Pssm-ID: 433519 [Multi-domain]  Cd Length: 65  Bit Score: 33.66  E-value: 9.01e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 296317276  104 GSGMVAE-PGTIAGVASALAMALIG--AVSSYISyqqkkfcfsiqqglnaDY--VKGENLEAVV 162
Cdd:pfam13840  13 GAGLDFDvPGVVAKLTSPLAEAGISifQISSYTT----------------DYvlVPEEDLEKAV 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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