NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|274325781|ref|NP_001162080|]
View 

F-actin-capping protein subunit alpha-2 [Macaca mulatta]

Protein Classification

F-actin-capping protein subunit alpha( domain architecture ID 10472626)

F-actin-capping protein subunit alpha binds in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
F-actin_cap_A pfam01267
F-actin capping protein alpha subunit;
17-282 3.99e-153

F-actin capping protein alpha subunit;


:

Pssm-ID: 460142  Cd Length: 263  Bit Score: 428.12  E-value: 3.99e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781   17 AAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICF 96
Cdd:pfam01267   1 ASSFILQAPPGELNEVVNDLRALLNDDSLLQEGIAPALEQYNEEQFTPVKLPGSSHQVIISEYNKLGDGRYFDPRSKKSF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781   97 KFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQtIIACIESHQFQAKNFWNGRWRSE 176
Cdd:pfam01267  81 KFDHLKQEASDVEPYELESELEELRKALEKALEKYVKEHYPSGVCTVYPKTEEDGK-LAICIVANKYNPSNFWNGRWRSE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781  177 WkfTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFK 256
Cdd:pfam01267 160 Y--TVDPSSGTLTGKIKVQVHYYEDGNVQLNTSKDVSESLPVSDPSQTASDIVKAIEEAENKYQTALNESYQNLSETTFK 237
                         250       260
                  ....*....|....*....|....*.
gi 274325781  257 ALRRQLPVTRTKIDWNKILSYKIGKE 282
Cdd:pfam01267 238 ALRRQLPVTRSKIDWGKIGNYRLGQD 263
 
Name Accession Description Interval E-value
F-actin_cap_A pfam01267
F-actin capping protein alpha subunit;
17-282 3.99e-153

F-actin capping protein alpha subunit;


Pssm-ID: 460142  Cd Length: 263  Bit Score: 428.12  E-value: 3.99e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781   17 AAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICF 96
Cdd:pfam01267   1 ASSFILQAPPGELNEVVNDLRALLNDDSLLQEGIAPALEQYNEEQFTPVKLPGSSHQVIISEYNKLGDGRYFDPRSKKSF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781   97 KFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQtIIACIESHQFQAKNFWNGRWRSE 176
Cdd:pfam01267  81 KFDHLKQEASDVEPYELESELEELRKALEKALEKYVKEHYPSGVCTVYPKTEEDGK-LAICIVANKYNPSNFWNGRWRSE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781  177 WkfTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFK 256
Cdd:pfam01267 160 Y--TVDPSSGTLTGKIKVQVHYYEDGNVQLNTSKDVSESLPVSDPSQTASDIVKAIEEAENKYQTALNESYQNLSETTFK 237
                         250       260
                  ....*....|....*....|....*.
gi 274325781  257 ALRRQLPVTRTKIDWNKILSYKIGKE 282
Cdd:pfam01267 238 ALRRQLPVTRSKIDWGKIGNYRLGQD 263
 
Name Accession Description Interval E-value
F-actin_cap_A pfam01267
F-actin capping protein alpha subunit;
17-282 3.99e-153

F-actin capping protein alpha subunit;


Pssm-ID: 460142  Cd Length: 263  Bit Score: 428.12  E-value: 3.99e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781   17 AAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICF 96
Cdd:pfam01267   1 ASSFILQAPPGELNEVVNDLRALLNDDSLLQEGIAPALEQYNEEQFTPVKLPGSSHQVIISEYNKLGDGRYFDPRSKKSF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781   97 KFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQtIIACIESHQFQAKNFWNGRWRSE 176
Cdd:pfam01267  81 KFDHLKQEASDVEPYELESELEELRKALEKALEKYVKEHYPSGVCTVYPKTEEDGK-LAICIVANKYNPSNFWNGRWRSE 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 274325781  177 WkfTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFK 256
Cdd:pfam01267 160 Y--TVDPSSGTLTGKIKVQVHYYEDGNVQLNTSKDVSESLPVSDPSQTASDIVKAIEEAENKYQTALNESYQNLSETTFK 237
                         250       260
                  ....*....|....*....|....*.
gi 274325781  257 ALRRQLPVTRTKIDWNKILSYKIGKE 282
Cdd:pfam01267 238 ALRRQLPVTRSKIDWGKIGNYRLGQD 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH