|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
56-311 |
9.08e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 119.65 E-value: 9.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 56 PNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQvemvaegAFRGLGRLLLLNLASNRLSTLPqEALDGLGSL 135
Cdd:COG4886 67 LLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 136 RRLELEGNMLEELrPGTFGALGSLTTLNLAHNALVYLPAmAFQGLLRTRWLQLSHNALSVLaPEALAGLPALRRLSLHHN 215
Cdd:COG4886 139 KELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 216 ELQALPgAALSQARSLARLELGHNPLTytgeedglALPGLRELaldhgslqalgprafahcPRLHTLDLRGNQLTTLPPL 295
Cdd:COG4886 216 QLTDLP-EPLANLTNLETLDLSNNQLT--------DLPELGNL------------------TNLEELDLSNNQLTDLPPL 268
|
250
....*....|....*.
gi 256222806 296 QVPGQLRRLRLQGNPL 311
Cdd:COG4886 269 ANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
444-676 |
3.01e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 118.11 E-value: 3.01e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 444 FPGLRHLVSLHLQHCGvaelepgALAGLDRLLYLYLSHNQLSGLSAAaLEGAPNLGYLYLEHNRFLRIPgTALRALPTLV 523
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLP-EPLGNLTNLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 524 SLHLQDNAVDRLaPGDLAGARALRCLYLSGNHITQVsPGALGPARELEKLHLDRNRLREVPTgALEGLPALKELQLSGNP 603
Cdd:COG4886 163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQ 239
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256222806 604 LRALPdgafqpvgrSLQQLflnssdleqisprafsglgKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPF 676
Cdd:COG4886 240 LTDLP---------ELGNL-------------------TNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
407-604 |
3.54e-16 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 78.29 E-value: 3.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 407 HSTCDGRGLQAVP--RGFPNdTQLLDLRRNHFPSVPraAFPGLRHLVSLHLQHCGVAELEPgaLAGLDRLLYLYLSHNQL 484
Cdd:cd21340 6 HLYLNDKNITKIDnlSLCKN-LKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 485 SGLSaaALEGAPNLGYLYLEHNRflripgtalraLPTLVSLHLQDNAVDRLAPgdlagarALRCLYLSGNHITQVSPgaL 564
Cdd:cd21340 81 SVVE--GLENLTNLEELHIENQR-----------LPPGEKLTFDPRSLAALSN-------SLRVLNISGNNIDSLEP--L 138
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 256222806 565 GPARELEKLHLDRNRLREVP--TGALEGLPALKELQLSGNPL 604
Cdd:cd21340 139 APLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
158-217 |
2.32e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.16 E-value: 2.32e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 158 SLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNEL 217
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
448-508 |
2.42e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 59.46 E-value: 2.42e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 448 RHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRF 508
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
415-641 |
5.90e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.87 E-value: 5.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 415 LQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPgalaglDRLLYLYLSHNQLSGLSAAALEG 494
Cdd:PRK15370 232 LTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLP------EELRYLSVYDNSIRTLPAHLPSG 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 495 apnLGYLYLEHNRFLRIPGTALRALPTLVSlhlQDNAVDRLaPGDLagARALRCLYLSGNHITqVSPGALGPAreLEKLH 574
Cdd:PRK15370 306 ---ITHLNVQSNSLTALPETLPPGLKTLEA---GENALTSL-PASL--PPELQVLDVSKNQIT-VLPETLPPT--ITTLD 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 575 LDRNRLREVPtgalEGLP-ALKELQLSGNPLRALPDG----------------AFQPVG-RSLQ--QLFLNSSDLEqiSP 634
Cdd:PRK15370 374 VSRNALTNLP----ENLPaALQIMQASRNNLVRLPESlphfrgegpqptriivEYNPFSeRTIQnmQRLMSSVGYQ--GP 447
|
....*..
gi 256222806 635 RAFSGLG 641
Cdd:PRK15370 448 RVLFAMG 454
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
21-311 |
9.54e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.49 E-value: 9.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 21 QSPAWHVAAQRCpQTCVCDNSRRhVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPaaafQDLphltHLDLRNCQVEmv 100
Cdd:PRK15370 161 EAANREEAVQRM-RDCLKNNKTE-LRLKILGLTTIPACIPEQITTLILDNNELKSLP----ENL----QGNIKTLYAN-- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 101 aegafrglgrllllnlaSNRLSTLPQEALDglgSLRRLELEGNMLEELrPGTFGAlgSLTTLNLAHNALVYLPAMAFQGL 180
Cdd:PRK15370 229 -----------------SNQLTSIPATLPD---TIQEMELSINRITEL-PERLPS--ALQSLDLFHNKISCLPENLPEEL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 181 lrtRWLQLSHNALSVLaPEALAGlpALRRLSLHHNELQALPgAALSQarSLARLELGHNPLTYTGEEdglALPGLRELAL 260
Cdd:PRK15370 286 ---RYLSVYDNSIRTL-PAHLPS--GITHLNVQSNSLTALP-ETLPP--GLKTLEAGENALTSLPAS---LPPELQVLDV 353
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 256222806 261 DHGSLQALgPRAFAhcPRLHTLDLRGNQLTTLPPlQVPGQLRRLRLQGNPL 311
Cdd:PRK15370 354 SKNQITVL-PETLP--PTITTLDVSRNALTNLPE-NLPAALQIMQASRNNL 400
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
44-221 |
3.65e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 57.49 E-value: 3.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 44 HVTCRHQNLTEVPNTI--PELTQrLDLQGNILKVLPAaaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNRL 121
Cdd:cd21340 6 HLYLNDKNITKIDNLSlcKNLKV-LYLYDNKITKIEN--LEFLTNLTHLYLQN------------------------NQI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 122 STLpqEALDGLGSLRRLELEGN------------MLEELR---------------PGTFGALG-SLTTLNLAHNALVYLp 173
Cdd:cd21340 59 EKI--ENLENLVNLKKLYLGGNrisvveglenltNLEELHienqrlppgekltfdPRSLAALSnSLRVLNISGNNIDSL- 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 256222806 174 aMAFQGLLRTRWLQLSHNALSVLAP--EALAGLPALRRLSLHHNELQALP 221
Cdd:cd21340 136 -EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
674-722 |
1.59e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 48.20 E-value: 1.59e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 256222806 674 NPFHCDCQLLPLHRWLTG---LNLRVGATCATPPSVRGQkVKVAAPVFEACP 722
Cdd:smart00082 1 NPFICDCELRWLLRWLQAnehLQDPVDLRCASPSSLRGP-LLELLHSEFKCP 51
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
663-709 |
7.20e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 53.16 E-value: 7.20e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 256222806 663 LSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPSVRGQ 709
Cdd:TIGR00864 18 LCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpeAALCAGPGALAGQ 68
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
394-428 |
2.08e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 39.22 E-value: 2.08e-04
10 20 30
....*....|....*....|....*....|....*
gi 256222806 394 PCPPACACVAetRHSTCDGRGLQAVPRGFPNDTQL 428
Cdd:smart00013 1 ACPAPCNCSG--TAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
591-614 |
2.95e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 35.41 E-value: 2.95e-03
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
32-64 |
3.98e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.37 E-value: 3.98e-03
10 20 30
....*....|....*....|....*....|...
gi 256222806 32 CPQTCVCdnSRRHVTCRHQNLTEVPNTIPELTQ 64
Cdd:smart00013 2 CPAPCNC--SGTAVDCSGRGLTEVPLDLPPDTT 32
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
394-423 |
4.81e-03 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 34.91 E-value: 4.81e-03
10 20 30
....*....|....*....|....*....|
gi 256222806 394 PCPPACACVAetRHSTCDGRGLQAVPRGFP 423
Cdd:pfam01462 1 ACPVPCHCSA--TVVNCSDRGLTAVPRDLP 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
56-311 |
9.08e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 119.65 E-value: 9.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 56 PNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQvemvaegAFRGLGRLLLLNLASNRLSTLPqEALDGLGSL 135
Cdd:COG4886 67 LLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 136 RRLELEGNMLEELrPGTFGALGSLTTLNLAHNALVYLPAmAFQGLLRTRWLQLSHNALSVLaPEALAGLPALRRLSLHHN 215
Cdd:COG4886 139 KELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 216 ELQALPgAALSQARSLARLELGHNPLTytgeedglALPGLRELaldhgslqalgprafahcPRLHTLDLRGNQLTTLPPL 295
Cdd:COG4886 216 QLTDLP-EPLANLTNLETLDLSNNQLT--------DLPELGNL------------------TNLEELDLSNNQLTDLPPL 268
|
250
....*....|....*.
gi 256222806 296 QVPGQLRRLRLQGNPL 311
Cdd:COG4886 269 ANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
444-676 |
3.01e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 118.11 E-value: 3.01e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 444 FPGLRHLVSLHLQHCGvaelepgALAGLDRLLYLYLSHNQLSGLSAAaLEGAPNLGYLYLEHNRFLRIPgTALRALPTLV 523
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLP-EPLGNLTNLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 524 SLHLQDNAVDRLaPGDLAGARALRCLYLSGNHITQVsPGALGPARELEKLHLDRNRLREVPTgALEGLPALKELQLSGNP 603
Cdd:COG4886 163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQ 239
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256222806 604 LRALPdgafqpvgrSLQQLflnssdleqisprafsglgKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPF 676
Cdd:COG4886 240 LTDLP---------ELGNL-------------------TNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
429-657 |
2.34e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.33 E-value: 2.34e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 429 LDLRRNHFPSVPrAAFPGLRHLVSLHLQHCGVAELePGALAGLDRLLYLYLSHNQLSGLSAAaLEGAPNLGYLYLEHNRF 508
Cdd:COG4886 118 LDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQI 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 509 LRIPgTALRALPTLVSLHLQDNAVDRLaPGDLAGARALRCLYLSGNHITQVSpgALGPARELEKLHLDRNRLREVPTgaL 588
Cdd:COG4886 195 TDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPP--L 268
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256222806 589 EGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLRSLYLHKNQLQSL 657
Cdd:COG4886 269 ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTL 337
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
43-266 |
4.05e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 96.54 E-value: 4.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 43 RHVTCRHQNLTEVPNTIPELT--QRLDLQGNILKVLPAAaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNR 120
Cdd:COG4886 139 KELDLSNNQLTDLPEPLGNLTnlKSLDLSNNQLTDLPEE-LGNLTNLKELDLSN------------------------NQ 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 121 LSTLPqEALDGLGSLRRLELEGNMLEELrPGTFGALGSLTTLNLAHNALVYLPAMAfqGLLRTRWLQLSHNALSVLAPea 200
Cdd:COG4886 194 ITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPELG--NLTNLEELDLSNNQLTDLPP-- 267
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256222806 201 LAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQ 266
Cdd:COG4886 268 LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGL 333
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
407-604 |
3.54e-16 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 78.29 E-value: 3.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 407 HSTCDGRGLQAVP--RGFPNdTQLLDLRRNHFPSVPraAFPGLRHLVSLHLQHCGVAELEPgaLAGLDRLLYLYLSHNQL 484
Cdd:cd21340 6 HLYLNDKNITKIDnlSLCKN-LKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 485 SGLSaaALEGAPNLGYLYLEHNRflripgtalraLPTLVSLHLQDNAVDRLAPgdlagarALRCLYLSGNHITQVSPgaL 564
Cdd:cd21340 81 SVVE--GLENLTNLEELHIENQR-----------LPPGEKLTFDPRSLAALSN-------SLRVLNISGNNIDSLEP--L 138
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 256222806 565 GPARELEKLHLDRNRLREVP--TGALEGLPALKELQLSGNPL 604
Cdd:cd21340 139 APLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
118-530 |
3.64e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 75.36 E-value: 3.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 118 SNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNAlvylpamAFQGLLRTRWLQLSHNALSVLa 197
Cdd:COG4886 57 LRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDL- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 198 PEALAGLPALRRLSLHHNELQALPgAALSQARSLARLELGHNPLTYTGEEDGlALPGLRELALDHGSLQALgPRAFAHCP 277
Cdd:COG4886 129 PEELANLTNLKELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDL-PEPLGNLT 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 278 RLHTLDLRGNQLTTLP-PLqvpGQLRRLrlqgnplwcacharpllewlvrarvrsdgacrgprrlrgealdtlrpsdlrc 356
Cdd:COG4886 206 NLEELDLSGNQLTDLPePL---ANLTNL---------------------------------------------------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 357 pgdaaagdgdgdededrpagprapplrsphgeaawatpcppacacvaetrhstcdgrglqavprgfpndtQLLDLRRNHF 436
Cdd:COG4886 231 ----------------------------------------------------------------------ETLDLSNNQL 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 437 PSVPraAFPGLRHLVSLHLQHCGVAELEPgaLAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTAL 516
Cdd:COG4886 241 TDLP--ELGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLIL 316
|
410
....*....|....
gi 256222806 517 RALPTLVSLHLQDN 530
Cdd:COG4886 317 LLLLTTLLLLLLLL 330
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
415-628 |
5.79e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.50 E-value: 5.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 415 LQAVPRGFPNDTQL--LDLRRNHFPSVPrAAFPGLRHLVSLHLQHCGVAELePGALAGLDRLLYLYLSHNQLSGLSAaaL 492
Cdd:COG4886 171 LTDLPEELGNLTNLkeLDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--L 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 493 EGAPNLGYLYLEHNRFLRIPgtALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEK 572
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLL 324
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 256222806 573 LHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSD 628
Cdd:COG4886 325 LLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLL 380
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
158-217 |
2.32e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.16 E-value: 2.32e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 158 SLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNEL 217
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
448-508 |
2.42e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 59.46 E-value: 2.42e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 448 RHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRF 508
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
415-641 |
5.90e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.87 E-value: 5.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 415 LQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPgalaglDRLLYLYLSHNQLSGLSAAALEG 494
Cdd:PRK15370 232 LTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLP------EELRYLSVYDNSIRTLPAHLPSG 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 495 apnLGYLYLEHNRFLRIPGTALRALPTLVSlhlQDNAVDRLaPGDLagARALRCLYLSGNHITqVSPGALGPAreLEKLH 574
Cdd:PRK15370 306 ---ITHLNVQSNSLTALPETLPPGLKTLEA---GENALTSL-PASL--PPELQVLDVSKNQIT-VLPETLPPT--ITTLD 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 575 LDRNRLREVPtgalEGLP-ALKELQLSGNPLRALPDG----------------AFQPVG-RSLQ--QLFLNSSDLEqiSP 634
Cdd:PRK15370 374 VSRNALTNLP----ENLPaALQIMQASRNNLVRLPESlphfrgegpqptriivEYNPFSeRTIQnmQRLMSSVGYQ--GP 447
|
....*..
gi 256222806 635 RAFSGLG 641
Cdd:PRK15370 448 RVLFAMG 454
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
21-311 |
9.54e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.49 E-value: 9.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 21 QSPAWHVAAQRCpQTCVCDNSRRhVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPaaafQDLphltHLDLRNCQVEmv 100
Cdd:PRK15370 161 EAANREEAVQRM-RDCLKNNKTE-LRLKILGLTTIPACIPEQITTLILDNNELKSLP----ENL----QGNIKTLYAN-- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 101 aegafrglgrllllnlaSNRLSTLPQEALDglgSLRRLELEGNMLEELrPGTFGAlgSLTTLNLAHNALVYLPAMAFQGL 180
Cdd:PRK15370 229 -----------------SNQLTSIPATLPD---TIQEMELSINRITEL-PERLPS--ALQSLDLFHNKISCLPENLPEEL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 181 lrtRWLQLSHNALSVLaPEALAGlpALRRLSLHHNELQALPgAALSQarSLARLELGHNPLTYTGEEdglALPGLRELAL 260
Cdd:PRK15370 286 ---RYLSVYDNSIRTL-PAHLPS--GITHLNVQSNSLTALP-ETLPP--GLKTLEAGENALTSLPAS---LPPELQVLDV 353
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 256222806 261 DHGSLQALgPRAFAhcPRLHTLDLRGNQLTTLPPlQVPGQLRRLRLQGNPL 311
Cdd:PRK15370 354 SKNQITVL-PETLP--PTITTLDVSRNALTNLPE-NLPAALQIMQASRNNL 400
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
134-193 |
2.65e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 56.38 E-value: 2.65e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 134 SLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNAL 193
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
43-261 |
8.57e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 61.49 E-value: 8.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 43 RHVTCRHQNLTEVPNTIPELT--QRLDLQGNILKVLPAAaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNR 120
Cdd:COG4886 185 KELDLSNNQITDLPEPLGNLTnlEELDLSGNQLTDLPEP-LANLTNLETLDLSN------------------------NQ 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 121 LSTLPQeaLDGLGSLRRLELEGNMLEELRPgtFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEA 200
Cdd:COG4886 240 LTDLPE--LGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLI 315
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 201 LAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALD 261
Cdd:COG4886 316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLE 376
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
568-629 |
1.29e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.45 E-value: 1.29e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256222806 568 RELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVgRSLQQLFLNSSDL 629
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGL-PSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
184-241 |
2.30e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.68 E-value: 2.30e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 256222806 184 RWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPL 241
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
44-221 |
3.65e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 57.49 E-value: 3.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 44 HVTCRHQNLTEVPNTI--PELTQrLDLQGNILKVLPAaaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNRL 121
Cdd:cd21340 6 HLYLNDKNITKIDNLSlcKNLKV-LYLYDNKITKIEN--LEFLTNLTHLYLQN------------------------NQI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 122 STLpqEALDGLGSLRRLELEGN------------MLEELR---------------PGTFGALG-SLTTLNLAHNALVYLp 173
Cdd:cd21340 59 EKI--ENLENLVNLKKLYLGGNrisvveglenltNLEELHienqrlppgekltfdPRSLAALSnSLRVLNISGNNIDSL- 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 256222806 174 aMAFQGLLRTRWLQLSHNALSVLAP--EALAGLPALRRLSLHHNELQALP 221
Cdd:cd21340 136 -EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
64-145 |
3.91e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.30 E-value: 3.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 64 QRLDLQGNILKVLPAAAFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNRLSTLPQEALDGLGSLRRLELEGN 143
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSN------------------------NLLTTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 256222806 144 ML 145
Cdd:pfam13855 60 RL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
544-604 |
6.50e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.53 E-value: 6.50e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 544 RALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPL 604
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
118-169 |
1.34e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 1.34e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 256222806 118 SNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNAL 169
Cdd:pfam13855 10 NNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
496-556 |
1.84e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.84e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 496 PNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHI 556
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
25-530 |
2.40e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 57.55 E-value: 2.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 25 WHVAAQRCP-QTCVCDNSRRHVTC--RHQNLT-EVPNTIPEL--TQRLDLQGNILK-VLPAAAFQDLPHLTHLDLRNCQV 97
Cdd:PLN00113 51 WNSSADVCLwQGITCNNSSRVVSIdlSGKNISgKISSAIFRLpyIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNF 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 98 EMVAEGAFRGLGRLLLLnlASNRLS-TLPQEaLDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALV-YLPAM 175
Cdd:PLN00113 131 TGSIPRGSIPNLETLDL--SNNMLSgEIPND-IGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVgQIPRE 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 176 AfqGLLRT-RWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLT------------ 242
Cdd:PLN00113 208 L--GQMKSlKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgpippsifslqk 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 243 ----------YTGE--EDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQ--LRRLRLQG 308
Cdd:PLN00113 286 lisldlsdnsLSGEipELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHnnLTVLDLST 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 309 NPLW-----CACHARPLLEWLVRARV------RSDGACRGPRRLR--GEALDTLRPSDL-RCPGDAAAGDGdgdededrp 374
Cdd:PLN00113 366 NNLTgeipeGLCSSGNLFKLILFSNSlegeipKSLGACRSLRRVRlqDNSFSGELPSEFtKLPLVYFLDIS--------- 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 375 agprAPPLRSPHGEAAWATPcppACACVAETRHSTCDGrglqaVPRGFPNDT-QLLDLRRNHFPSVPRAAFPGLRHLVSL 453
Cdd:PLN00113 437 ----NNNLQGRINSRKWDMP---SLQMLSLARNKFFGG-----LPDSFGSKRlENLDLSRNQFSGAVPRKLGSLSELMQL 504
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256222806 454 HLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFL-RIPgTALRALPTLVSLHLQDN 530
Cdd:PLN00113 505 KLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIP-KNLGNVESLVQVNISHN 581
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
253-311 |
3.40e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.60 E-value: 3.40e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 253 PGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPP--LQVPGQLRRLRLQGNPL 311
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
411-602 |
5.99e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 55.05 E-value: 5.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 411 DGRGLQAVPRGFPNDTQL--LDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGL--------DRLLYLYLS 480
Cdd:cd00116 66 IPRGLQSLLQGLTKGCGLqeLDLSDNALGPDGCGVLESLLRSSSLQELKLNNNGLGDRGLRLLakglkdlpPALEKLVLG 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 481 HNQLSGLSAAALEGapnlgylylehnrflripgtALRALPTLVSLHLQDNAVD-----RLAPGdLAGARALRCLYLSGNH 555
Cdd:cd00116 146 RNRLEGASCEALAK--------------------ALRANRDLKELNLANNGIGdagirALAEG-LKANCNLEVLDLNNNG 204
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 256222806 556 ITQVSPGALGPA----RELEKLHLDRNRLREVPTGAL-----EGLPALKELQLSGN 602
Cdd:cd00116 205 LTDEGASALAETlaslKSLEVLNLGDNNLTDAGAAALasallSPNISLLTLSLSCN 260
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
465-676 |
6.23e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 56.39 E-value: 6.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 465 PGALAGLDRLLYLYLSHNQLSG--------LSA----------------AALEGAPNLGYLYLEHNRFL-RIPGTALrAL 519
Cdd:PLN00113 205 PRELGQMKSLKWIYLGYNNLSGeipyeiggLTSlnhldlvynnltgpipSSLGNLKNLQYLFLYQNKLSgPIPPSIF-SL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 520 PTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLR-EVPTGaLEGLPALKELQ 598
Cdd:PLN00113 284 QKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSgEIPKN-LGKHNNLTVLD 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 599 LSGNPLRA-LPDGAFQPvGRsLQQLFLNSSDLEQISPRAFSGLgKGLRSLYLHKNQLqSLPAPLGLSGLELV---DLSGN 674
Cdd:PLN00113 363 LSTNNLTGeIPEGLCSS-GN-LFKLILFSNSLEGEIPKSLGAC-RSLRRVRLQDNSF-SGELPSEFTKLPLVyflDISNN 438
|
..
gi 256222806 675 PF 676
Cdd:PLN00113 439 NL 440
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
156-311 |
6.66e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 53.64 E-value: 6.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 156 LGSLTTLNLAHNALVYLPAMAFQGLLRTrwLQLSHNALSVLapEALAGLPALRRLSLHHNELQALPGaaLSQARSLARLE 235
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNLSLCKNLKV--LYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 236 LGHNPLTytgEEDGLA-LPGLRELALDHGSLQ-----ALGPRA-FAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQG 308
Cdd:cd21340 75 LGGNRIS---VVEGLEnLTNLEELHIENQRLPpgeklTFDPRSlAALSNSLRVLNISGNNIDSLEPLAPLRNLEQLDASN 151
|
...
gi 256222806 309 NPL 311
Cdd:cd21340 152 NQI 154
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
674-722 |
1.59e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 48.20 E-value: 1.59e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 256222806 674 NPFHCDCQLLPLHRWLTG---LNLRVGATCATPPSVRGQkVKVAAPVFEACP 722
Cdd:smart00082 1 NPFICDCELRWLLRWLQAnehLQDPVDLRCASPSSLRGP-LLELLHSEFKCP 51
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
429-484 |
2.23e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.29 E-value: 2.23e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 256222806 429 LDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQL 484
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
64-241 |
5.87e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 53.31 E-value: 5.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 64 QRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLS-TLPQeaLDGLGSLRRLELEG 142
Cdd:PLN00113 407 RRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFgGLPD--SFGSKRLENLDLSR 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 143 NMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPG 222
Cdd:PLN00113 485 NQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIP 564
|
170
....*....|....*....
gi 256222806 223 AALSQARSLARLELGHNPL 241
Cdd:PLN00113 565 KNLGNVESLVQVNISHNHL 583
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
49-215 |
5.96e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 53.16 E-value: 5.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 49 HQNLTEVPNTIPELTQRLDLQGNILKVLPAaafqDLPH-LTHLDLRNCQVEMVAEgafRGLGRLLLLNLASNRLSTLPqE 127
Cdd:PRK15370 271 HNKISCLPENLPEELRYLSVYDNSIRTLPA----HLPSgITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLP-A 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 128 ALDglGSLRRLELEGN---MLEELRPGTfgalgsLTTLNLAHNALVYLPAMAFQGLlrtRWLQLSHNALSVLaPEALAGL 204
Cdd:PRK15370 343 SLP--PELQVLDVSKNqitVLPETLPPT------ITTLDVSRNALTNLPENLPAAL---QIMQASRNNLVRL-PESLPHF 410
|
170
....*....|....*
gi 256222806 205 ----PALRRLSLHHN 215
Cdd:PRK15370 411 rgegPQPTRIIVEYN 425
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
520-580 |
7.03e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 7.03e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256222806 520 PTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRL 580
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
663-709 |
7.20e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 53.16 E-value: 7.20e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 256222806 663 LSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPSVRGQ 709
Cdd:TIGR00864 18 LCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpeAALCAGPGALAGQ 68
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
479-674 |
8.40e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 52.54 E-value: 8.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 479 LSHNQLSG-LSAAALEGAPNLGYLYLEHNRFL-RIPGTALralPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHI 556
Cdd:PLN00113 100 LSNNQLSGpIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSI---PNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 557 TQVSPGALGPARELEKLHLDRNRLR-EVPTgALEGLPALKELQLSGNPLRA-LPdgafQPVGR--SLQQLFLNSSDLEQI 632
Cdd:PLN00113 177 VGKIPNSLTNLTSLEFLTLASNQLVgQIPR-ELGQMKSLKWIYLGYNNLSGeIP----YEIGGltSLNHLDLVYNNLTGP 251
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 256222806 633 SPRAFSGLgKGLRSLYLHKNQL--QSLPAPLGLSGLELVDLSGN 674
Cdd:PLN00113 252 IPSSLGNL-KNLQYLFLYQNKLsgPIPPSIFSLQKLISLDLSDN 294
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
127-311 |
1.87e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.40 E-value: 1.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 127 EALDGLGSLRRLELEGNMLEELRPgtFGALGSLTTLNLAHNALVYLPAmaFQGLLRTRWLQLSHNALSVLapEALAGLPA 206
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVV--EGLENLTN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 207 LRRLSLHHNELQA------LPGAALSQARSLARLELGHNPLTytgeedglalpglrelaldhgSLQALgprafAHCPRLH 280
Cdd:cd21340 92 LEELHIENQRLPPgekltfDPRSLAALSNSLRVLNISGNNID---------------------SLEPL-----APLRNLE 145
|
170 180 190
....*....|....*....|....*....|....*
gi 256222806 281 TLDLRGNQLTTLPPLQVP----GQLRRLRLQGNPL 311
Cdd:cd21340 146 QLDASNNQISDLEELLDLlsswPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
205-289 |
2.97e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 2.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 205 PALRRLSLHHNELQALPGAALSQARSLARLELGHNpltytgeedglalpglrelaldhgSLQALGPRAFAHCPRLHTLDL 284
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN------------------------LLTTLSPGAFSGLPSLRYLDL 56
|
....*
gi 256222806 285 RGNQL 289
Cdd:pfam13855 57 SGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
414-676 |
3.19e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 50.55 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 414 GLQAVPRGFPNDTQLLDLRRNHFPSVPrAAFPGLRHLVSLHLQHCGVAELEPGalagldrLLYLYLSHNQLSGLSAAAle 493
Cdd:PRK15387 212 GLTTLPDCLPAHITTLVIPDNNLTSLP-ALPPELRTLEVSGNQLTSLPVLPPG-------LLELSIFSNPLTHLPALP-- 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 494 gaPNLGYLYLEHNRFLRIPGTAlralPTLVSLHLQDNAVDRLA--PGDLAGaralrcLYLSGNHITQVSPGALGpareLE 571
Cdd:PRK15387 282 --SGLCKLWIFGNQLTSLPVLP----PGLQELSVSDNQLASLPalPSELCK------LWAYNNQLTSLPTLPSG----LQ 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 572 KLHLDRNRLREVPT------------GALEGLPAL----KELQLSGNPLRALPdgafqPVGRSLQQLFLNSSDLEQISPr 635
Cdd:PRK15387 346 ELSVSDNQLASLPTlpselyklwaynNRLTSLPALpsglKELIVSGNRLTSLP-----VLPSELKELMVSGNRLTSLPM- 419
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 256222806 636 afsgLGKGLRSLYLHKNQLQSLPAPL-GLSGLELVDLSGNPF 676
Cdd:PRK15387 420 ----LPSGLLSLSVYRNQLTRLPESLiHLSSETTVNLEGNPL 457
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
132-508 |
3.29e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 50.62 E-value: 3.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 132 LGSLRRLE---LEGNMLEELRPGTFGALGSLTTLNLAHNALV-YLPAMAFQgLLRTRWLQLSHNALSVLAPEALAGLPAL 207
Cdd:PLN00113 256 LGNLKNLQylfLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQ-LQNLEILHLFSNNFTGKIPVALTSLPRL 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 208 RRLSLHHNELQALPGAALSQARSLARLELGHNPLTytGE-EDGLALPG-LRELALDHGSLQALGPRAFAHCPRLHTLDLR 285
Cdd:PLN00113 335 QVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLT--GEiPEGLCSSGnLFKLILFSNSLEGEIPKSLGACRSLRRVRLQ 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 286 GNQLT-TLP------PLQVPGQLRRLRLQGN---PLWcachARPLLEWLVRARVRSDGACrgPRRLRGEALDTLrpsDLr 355
Cdd:PLN00113 413 DNSFSgELPseftklPLVYFLDISNNNLQGRinsRKW----DMPSLQMLSLARNKFFGGL--PDSFGSKRLENL---DL- 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 356 cpgdaaagdgdgdededrpagprapplrsphgeaawatpcppacacvAETRHStcdgrglQAVPRGFPNDTQLLDLR--R 433
Cdd:PLN00113 483 -----------------------------------------------SRNQFS-------GAVPRKLGSLSELMQLKlsE 508
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256222806 434 NHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRF 508
Cdd:PLN00113 509 NKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
473-530 |
3.99e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 3.99e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 256222806 473 RLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDN 530
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
617-676 |
7.26e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 7.26e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256222806 617 RSLQQLFLNSSDLEQISPRAFSGLgKGLRSLYLHKNQLQSLP--APLGLSGLELVDLSGNPF 676
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGL-SNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
64-291 |
8.60e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 48.51 E-value: 8.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 64 QRLDLQGNILKVLPAAAFQDL---PHLTHLDLRNCQVE-----MVAEGAfrglgrllllnlasnrlsTLPQEALDGLGSL 135
Cdd:cd00116 84 QELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGdrglrLLAKGL------------------KDLPPALEKLVLG 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 136 RRLeLEGNMLEELrPGTFGALGSLTTLNLAHNalvylpamafqgllrtrwlQLSHNALSVLApEALAGLPALRRLSLHHN 215
Cdd:cd00116 146 RNR-LEGASCEAL-AKALRANRDLKELNLANN-------------------GIGDAGIRALA-EGLKANCNLEVLDLNNN 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 216 EL-----QALpGAALSQARSLARLELGHNPLTYTG-----EEDGLALPGLRELALDHGSLQALGPRAFAHC----PRLHT 281
Cdd:cd00116 204 GLtdegaSAL-AETLASLKSLEVLNLGDNNLTDAGaaalaSALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLE 282
|
250
....*....|
gi 256222806 282 LDLRGNQLTT 291
Cdd:cd00116 283 LDLRGNKFGE 292
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
127-318 |
1.92e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.86 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 127 EALDGLGSLRRLELEGN---------MLEELRPGTfgalgSLTTLNLAHNalvylpamafqgllrtrwlQLSHNALSVLA 197
Cdd:COG5238 230 EALKGNKSLTTLDLSNNqigdegviaLAEALKNNT-----TVETLYLSGN-------------------QIGAEGAIALA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 198 pEALAGLPALRRLSLHHNELQAlPGA-----ALSQARSLARLELGHNPLTYTGEEdGLA-----LPGLRELALDHGSLQA 267
Cdd:COG5238 286 -KALQGNTTLTSLDLSVNRIGD-EGAialaeGLQGNKTLHTLNLAYNGIGAQGAI-ALAkalqeNTTLHSLDLSDNQIGD 362
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 268 LGPRAFAH----CPRLHTLDLRGNQLT-----TLPPLQVPGQLRRLRLQGNPLWCACHAR 318
Cdd:COG5238 363 EGAIALAKylegNTTLRELNLGKNNIGkqgaeALIDALQTNRLHTLILDGNLIGAEAQQR 422
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
467-595 |
2.03e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.86 E-value: 2.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 467 ALAGLDRLLYLYLSHNQLSGLSAAA----LEGAPNLGYLYLEHN-------RFLripGTALRALPTLVSLHLQDNAVdrl 535
Cdd:COG5238 287 ALQGNTTLTSLDLSVNRIGDEGAIAlaegLQGNKTLHTLNLAYNgigaqgaIAL---AKALQENTTLHSLDLSDNQI--- 360
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256222806 536 apGD---------LAGARALRCLYLSGNHITQVSPGALGPARELEKLH---LDRNRLREVPTGAL-EGLPALK 595
Cdd:COG5238 361 --GDegaialakyLEGNTTLRELNLGKNNIGKQGAEALIDALQTNRLHtliLDGNLIGAEAQQRLeQLLERIK 431
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
449-674 |
2.31e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.48 E-value: 2.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 449 HLVSLHLQHCGVAELEPGALAGLD-RLLYLYLSHNQLS--GLS--AAALEGAPNLGYLYLEHNRF----LRIPGTALRAL 519
Cdd:COG5238 156 VHLLGLAARLGLLAAISMAKALQNnSVETVYLGCNQIGdeGIEelAEALTQNTTVTTLWLKRNPIgdegAEILAEALKGN 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 520 PTLVSLHLQDNAVDrlAPGDLAGARALRC------LYLSGNHITqvSPGALGPARELEK------LHLDRNRLREvpTGA 587
Cdd:COG5238 236 KSLTTLDLSNNQIG--DEGVIALAEALKNnttvetLYLSGNQIG--AEGAIALAKALQGnttltsLDLSVNRIGD--EGA 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 588 ------LEGLPALKELQLSGNPLRAlpDGAfQPVGRSLQQLF-LNSSDLE--QISPRAFSGLGK------GLRSLYLHKN 652
Cdd:COG5238 310 ialaegLQGNKTLHTLNLAYNGIGA--QGA-IALAKALQENTtLHSLDLSdnQIGDEGAIALAKylegntTLRELNLGKN 386
|
250 260
....*....|....*....|....*..
gi 256222806 653 QL-----QSLPAPLGLSGLELVDLSGN 674
Cdd:COG5238 387 NIgkqgaEALIDALQTNRLHTLILDGN 413
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
170-612 |
3.28e-05 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 47.56 E-value: 3.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 170 VYLPAMAFQgllRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDG 249
Cdd:COG3321 861 VPLPTYPFQ---REDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAA 937
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 250 LALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARV 329
Cdd:COG3321 938 AAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAA 1017
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 330 RSDGACRGPRRLRGEALDTLRPSDLRcpgdaaagdgdgDEDEDRPAGPRAPPLRSPHGEAAWATPCPPACACVAETRHST 409
Cdd:COG3321 1018 AAALLALAALLAAAAAALAAAAAAAA------------AAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALA 1085
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 410 CDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSA 489
Cdd:COG3321 1086 LAAALAAAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAA 1165
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 490 AALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARE 569
Cdd:COG3321 1166 ALLAAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAV 1245
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 256222806 570 LEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAF 612
Cdd:COG3321 1246 AALAAAAAALLAALAALALLAAAAGLAALAAAAAAAAAALALA 1288
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
447-677 |
6.12e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 46.76 E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 447 LRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFL-RIPGTaLRALPTLVSL 525
Cdd:PLN00113 307 LQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgEIPEG-LCSSGNLFKL 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 526 HLQDNAVDRLAPGDLAGARALRCLYLSGNHIT----------------QVS----------------------------- 560
Cdd:PLN00113 386 ILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSgelpseftklplvyflDISnnnlqgrinsrkwdmpslqmlslarnkff 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 561 ---PGALGpARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRA-LPDGAfqPVGRSLQQLFLNSSDLEQISPRA 636
Cdd:PLN00113 466 gglPDSFG-SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGeIPDEL--SSCKKLVSLDLSHNQLSGQIPAS 542
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 256222806 637 FSGLgKGLRSLYLHKNQLQ-SLPAPLG-LSGLELVDLSGNPFH 677
Cdd:PLN00113 543 FSEM-PVLSQLDLSQNQLSgEIPKNLGnVESLVQVNISHNHLH 584
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
76-547 |
7.11e-05 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 46.40 E-value: 7.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 76 LPAAAFQdLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGA 155
Cdd:COG3321 863 LPTYPFQ-REDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAA 941
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 156 LGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLE 235
Cdd:COG3321 942 LLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAAL 1021
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 236 LGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCAC 315
Cdd:COG3321 1022 LALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAA 1101
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 316 HARPLLEWLVRARVRSDGACRGPRRLRGEALDTLRPSDLRCPGDAAAGDGDGDEDEDRPAGPRAPPLRSPHGEAAWATPC 395
Cdd:COG3321 1102 LAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALAL 1181
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 396 PPACACVAETRHSTcDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLL 475
Cdd:COG3321 1182 AAALAAALAGLAAL-LLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALA 1260
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256222806 476 YLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALR 547
Cdd:COG3321 1261 ALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAA 1332
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
119-311 |
1.22e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 45.54 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 119 NRLSTLPQEALDglgsLRRLELEGNMLEELR---PGtfgalgsLTTLNLAHNALVYLPAMAfQGLLRTRWLQLSHNALSV 195
Cdd:PRK15387 232 NNLTSLPALPPE----LRTLEVSGNQLTSLPvlpPG-------LLELSIFSNPLTHLPALP-SGLCKLWIFGNQLTSLPV 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 196 LAPealaglpALRRLSLHHNELQALPgaalSQARSLARLELGHNPLTytgeedglALP----GLRELALDHGSLQALGP- 270
Cdd:PRK15387 300 LPP-------GLQELSVSDNQLASLP----ALPSELCKLWAYNNQLT--------SLPtlpsGLQELSVSDNQLASLPTl 360
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 256222806 271 -----RAFAHCPRLHTLD----------LRGNQLTTLPPLqvPGQLRRLRLQGNPL 311
Cdd:PRK15387 361 pselyKLWAYNNRLTSLPalpsglkeliVSGNRLTSLPVL--PSELKELMVSGNRL 414
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
474-676 |
1.66e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.22 E-value: 1.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 474 LLYLYLSHNQLSGLSAAAleGAPNLGYLYLEHNRFL-RIPgTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLS 552
Cdd:PLN00113 120 LRYLNLSNNNFTGSIPRG--SIPNLETLDLSNNMLSgEIP-NDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 553 GNHITQVSPGALGPARELEKLHLDRNRLR-EVPTgALEGLPALKELQLSGNPLRALPDGAFQPVgRSLQQLFLNSSDLEQ 631
Cdd:PLN00113 197 SNQLVGQIPRELGQMKSLKWIYLGYNNLSgEIPY-EIGGLTSLNHLDLVYNNLTGPIPSSLGNL-KNLQYLFLYQNKLSG 274
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 256222806 632 ISPRAFSGLGKgLRSLYLHKNQLqSLPAP---LGLSGLELVDLSGNPF 676
Cdd:PLN00113 275 PIPPSIFSLQK-LISLDLSDNSL-SGEIPelvIQLQNLEILHLFSNNF 320
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
394-428 |
2.08e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 39.22 E-value: 2.08e-04
10 20 30
....*....|....*....|....*....|....*
gi 256222806 394 PCPPACACVAetRHSTCDGRGLQAVPRGFPNDTQL 428
Cdd:smart00013 1 ACPAPCNCSG--TAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
129-257 |
3.58e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 44.04 E-value: 3.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256222806 129 LDGLGslrrLELEGnmLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALR 208
Cdd:PLN03150 420 IDGLG----LDNQG--LRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLR 493
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 256222806 209 RLSLHHNELQA-LPGAALSQARSLARLELGHNPltytgeedGL-ALPGLRE 257
Cdd:PLN03150 494 ILNLNGNSLSGrVPAALGGRLLHRASFNFTDNA--------GLcGIPGLRA 536
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
642-675 |
8.44e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 37.61 E-value: 8.44e-04
10 20 30
....*....|....*....|....*....|....
gi 256222806 642 KGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNP 675
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNN 34
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
591-614 |
2.95e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 35.41 E-value: 2.95e-03
|
| LRR_TYP |
smart00369 |
Leucine-rich repeats, typical (most populated) subfamily; |
591-614 |
2.95e-03 |
|
Leucine-rich repeats, typical (most populated) subfamily;
Pssm-ID: 197687 [Multi-domain] Cd Length: 24 Bit Score: 35.41 E-value: 2.95e-03
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
32-64 |
3.98e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.37 E-value: 3.98e-03
10 20 30
....*....|....*....|....*....|...
gi 256222806 32 CPQTCVCdnSRRHVTCRHQNLTEVPNTIPELTQ 64
Cdd:smart00013 2 CPAPCNC--SGTAVDCSGRGLTEVPLDLPPDTT 32
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
394-423 |
4.81e-03 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 34.91 E-value: 4.81e-03
10 20 30
....*....|....*....|....*....|
gi 256222806 394 PCPPACACVAetRHSTCDGRGLQAVPRGFP 423
Cdd:pfam01462 1 ACPVPCHCSA--TVVNCSDRGLTAVPRDLP 28
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
277-311 |
5.49e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 5.49e-03
10 20 30
....*....|....*....|....*....|....*
gi 256222806 277 PRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPL 311
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNK 35
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
570-604 |
5.54e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 5.54e-03
10 20 30
....*....|....*....|....*....|....*
gi 256222806 570 LEKLHLDRNRLREVPtgALEGLPALKELQLSGNPL 604
Cdd:pfam12799 3 LEVLDLSNNQITDIP--PLAKLPNLETLDLSGNNK 35
|
|
| |
