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Conserved domains on  [gi|256221758|ref|NP_001157778|]
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flavin-containing monooxygenase 13 [Mus musculus]

Protein Classification

flavin-binding monooxygenase-like family protein( domain architecture ID 1000557)

flavin-binding monooxygenase-like family protein; such as flavin-containing monooxygenases (FMOs) that catalyze the monooxygenation of a variety of substrates

EC:  1.14.13.-
Gene Ontology:  GO:0004497

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like super family cl30939
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 4-532 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


The actual alignment was detected with superfamily member pfam00743:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 787.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758    4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPENGRPGIYKSLTCNTSKEMTTFSDYPIPDHYPNYM 83
Cdd:pfam00743   2 KKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNFM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   84 HHSKMMEYLRMYARHFGLMKHIQFQTRVCVVRKRPDFSSSGQWDVVVEADGKQKNYIFDGVMVCSGHYTEKYLPLQDFAG 163
Cdd:pfam00743  82 HNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFPG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  164 ISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRRGTWIWNRVWDNGDPLDIALFTRYNRT 243
Cdd:pfam00743 162 IEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTSF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  244 VKSFYPTFLINRWTENKLNLRFNHANYGLQAKHRFLSHQSIFSDDLPNRIISGRVLVKTNVREFTSTSAIFEDGS-EEIV 322
Cdd:pfam00743 242 LRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTvEEDI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  323 DVVVFATGYTLSFPFLDDSS-EILDSKHTMFKFVFPPQLEKPTLAFIGILQPIGATIPTSELQSRWVTRVFAGLQKLPSQ 401
Cdd:pfam00743 322 DVVIFATGYTFAFPFLEESLvKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPSQ 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  402 SNMMADINRKKRKMEKEFVKSPRDVRRVPYIDYMDEIASEIGVKPNLLSFFLWDTKLAKEIFWGPCTPYQYRLQGPGKWA 481
Cdd:pfam00743 402 SEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKWE 481

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 256221758  482 GARAAILTQRDRILKPLRSRVLKNSETSSSSlFWVRCICAVIFpFVSVFAI 532
Cdd:pfam00743 482 GARNAILTQWDRILKPLKTRVVEKSSSPASS-FTLKIFGLPVV-LVAIFLI 530
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 4-532 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 787.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758    4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPENGRPGIYKSLTCNTSKEMTTFSDYPIPDHYPNYM 83
Cdd:pfam00743   2 KKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNFM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   84 HHSKMMEYLRMYARHFGLMKHIQFQTRVCVVRKRPDFSSSGQWDVVVEADGKQKNYIFDGVMVCSGHYTEKYLPLQDFAG 163
Cdd:pfam00743  82 HNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFPG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  164 ISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRRGTWIWNRVWDNGDPLDIALFTRYNRT 243
Cdd:pfam00743 162 IEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTSF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  244 VKSFYPTFLINRWTENKLNLRFNHANYGLQAKHRFLSHQSIFSDDLPNRIISGRVLVKTNVREFTSTSAIFEDGS-EEIV 322
Cdd:pfam00743 242 LRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTvEEDI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  323 DVVVFATGYTLSFPFLDDSS-EILDSKHTMFKFVFPPQLEKPTLAFIGILQPIGATIPTSELQSRWVTRVFAGLQKLPSQ 401
Cdd:pfam00743 322 DVVIFATGYTFAFPFLEESLvKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPSQ 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  402 SNMMADINRKKRKMEKEFVKSPRDVRRVPYIDYMDEIASEIGVKPNLLSFFLWDTKLAKEIFWGPCTPYQYRLQGPGKWA 481
Cdd:pfam00743 402 SEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKWE 481

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 256221758  482 GARAAILTQRDRILKPLRSRVLKNSETSSSSlFWVRCICAVIFpFVSVFAI 532
Cdd:pfam00743 482 GARNAILTQWDRILKPLKTRVVEKSSSPASS-FTLKIFGLPVV-LVAIFLI 530
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-397 8.36e-86

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 271.35  E-value: 8.36e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   1 MEVKQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKEtpengrpgiYKSLTCNTSKEMTTFSDYPIPDHYP 80
Cdd:COG2072    4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNR---------YPGLRLDTPSHLYSLPFFPNWSDDP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  81 NYMHHSKMMEYLRMYARHFGLMKHIQFQTRVCVVRKRPDfssSGQWDVVVEaDGKQknYIFDGVMVCSGHYTEKYLPlqD 160
Cdd:COG2072   75 DFPTGDEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTTD-DGET--LTARFVVVATGPLSRPKIP--D 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 161 FAGISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRRGTWI---WNRVWDNGDPLDIALF 237
Cdd:COG2072  147 IPGLEDFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVlprPNYDPERGRPANYLGL 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 238 TRYNRTVKsfyptFLINRWTENKLNLRFNHANYG-LQAKHRFLSHQSIFSDDLPNRIISGRV-LVKTNVREFTSTSAIFE 315
Cdd:COG2072  227 EAPPALNR-----RDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVeLVTGGIERITEDGVVFA 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 316 DGSEEIVDVVVFATGYTLSFPFLdDSSEILD----SKHTMFKFVFPPQLekPTLAFIGILQPIG--ATIPTSELQSRWVT 389
Cdd:COG2072  302 DGTEHEVDVIVWATGFRADLPWL-APLDVRGrdgrSGPRAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARYIA 378


                 ....*...
gi 256221758 390 RVFAGLQK 397
Cdd:COG2072  379 RLIAHMRR 386
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 4-446 1.21e-45

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 166.58  E-value: 1.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPEN-------GRP----GIYKSLTCNTSKEMTTFSD 72
Cdd:PLN02172  11 QHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESdplsldpTRSivhsSVYESLRTNLPRECMGYRD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  73 YPI----------PDHYPNymhHSKMMEYLRMYARHFGLMKHIQFQTRVcvVRKRPdfsSSGQWDVVVE-ADGKQKNYIF 141
Cdd:PLN02172  91 FPFvprfddesrdSRRYPS---HREVLAYLQDFAREFKIEEMVRFETEV--VRVEP---VDGKWRVQSKnSGGFSKDEIF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 142 DGVMVCSGHYTE---KYLPlqdfaGISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRrg 218
Cdd:PLN02172 163 DAVVVCNGHYTEpnvAHIP-----GIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASR-- 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 219 twiwnrvwdngdpldialfTRYNRTVKSFyPTFLINRWTENKLNlrfnhanyglqakhrfLSHQsifsddlpnriisgrv 298
Cdd:PLN02172 236 -------------------ASESDTYEKL-PVPQNNLWMHSEID----------------TAHE---------------- 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 299 lvktnvreftSTSAIFEDGSEEIVDVVVFATGYTLSFPFLDDSSEI-LDSKHT--MFKFVFPPQLeKPTLAFIGiLQPIG 375
Cdd:PLN02172 264 ----------DGSIVFKNGKVVYADTIVHCTGYKYHFPFLETNGYMrIDENRVepLYKHVFPPAL-APGLSFIG-LPAMG 331

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256221758 376 ATIPTSELQSRWVTRVFAGLQKLPSQSNMMADINRKKRKMEKeFVKSPRDVRRVPYI--DYMDEIASEIGVKP 446
Cdd:PLN02172 332 IQFVMFEIQSKWVAAVLSGRVTLPSEDKMMEDINAWYASLEA-LGIPKRYTHKLGKIqsEYLNWIAEECGCPL 403
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 4-532 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 787.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758    4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPENGRPGIYKSLTCNTSKEMTTFSDYPIPDHYPNYM 83
Cdd:pfam00743   2 KKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNFM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   84 HHSKMMEYLRMYARHFGLMKHIQFQTRVCVVRKRPDFSSSGQWDVVVEADGKQKNYIFDGVMVCSGHYTEKYLPLQDFAG 163
Cdd:pfam00743  82 HNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFPG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  164 ISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRRGTWIWNRVWDNGDPLDIALFTRYNRT 243
Cdd:pfam00743 162 IEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTSF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  244 VKSFYPTFLINRWTENKLNLRFNHANYGLQAKHRFLSHQSIFSDDLPNRIISGRVLVKTNVREFTSTSAIFEDGS-EEIV 322
Cdd:pfam00743 242 LRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTvEEDI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  323 DVVVFATGYTLSFPFLDDSS-EILDSKHTMFKFVFPPQLEKPTLAFIGILQPIGATIPTSELQSRWVTRVFAGLQKLPSQ 401
Cdd:pfam00743 322 DVVIFATGYTFAFPFLEESLvKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPSQ 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  402 SNMMADINRKKRKMEKEFVKSPRDVRRVPYIDYMDEIASEIGVKPNLLSFFLWDTKLAKEIFWGPCTPYQYRLQGPGKWA 481
Cdd:pfam00743 402 SEMMAEINKRQEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKWE 481

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 256221758  482 GARAAILTQRDRILKPLRSRVLKNSETSSSSlFWVRCICAVIFpFVSVFAI 532
Cdd:pfam00743 482 GARNAILTQWDRILKPLKTRVVEKSSSPASS-FTLKIFGLPVV-LVAIFLI 530
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-397 8.36e-86

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 271.35  E-value: 8.36e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   1 MEVKQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKEtpengrpgiYKSLTCNTSKEMTTFSDYPIPDHYP 80
Cdd:COG2072    4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRDNR---------YPGLRLDTPSHLYSLPFFPNWSDDP 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  81 NYMHHSKMMEYLRMYARHFGLMKHIQFQTRVCVVRKRPDfssSGQWDVVVEaDGKQknYIFDGVMVCSGHYTEKYLPlqD 160
Cdd:COG2072   75 DFPTGDEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTTD-DGET--LTARFVVVATGPLSRPKIP--D 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 161 FAGISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRRGTWI---WNRVWDNGDPLDIALF 237
Cdd:COG2072  147 IPGLEDFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVlprPNYDPERGRPANYLGL 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 238 TRYNRTVKsfyptFLINRWTENKLNLRFNHANYG-LQAKHRFLSHQSIFSDDLPNRIISGRV-LVKTNVREFTSTSAIFE 315
Cdd:COG2072  227 EAPPALNR-----RDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVeLVTGGIERITEDGVVFA 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 316 DGSEEIVDVVVFATGYTLSFPFLdDSSEILD----SKHTMFKFVFPPQLekPTLAFIGILQPIG--ATIPTSELQSRWVT 389
Cdd:COG2072  302 DGTEHEVDVIVWATGFRADLPWL-APLDVRGrdgrSGPRAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARYIA 378


                 ....*...
gi 256221758 390 RVFAGLQK 397
Cdd:COG2072  379 RLIAHMRR 386
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 4-446 1.21e-45

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 166.58  E-value: 1.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPEN-------GRP----GIYKSLTCNTSKEMTTFSD 72
Cdd:PLN02172  11 QHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESdplsldpTRSivhsSVYESLRTNLPRECMGYRD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  73 YPI----------PDHYPNymhHSKMMEYLRMYARHFGLMKHIQFQTRVcvVRKRPdfsSSGQWDVVVE-ADGKQKNYIF 141
Cdd:PLN02172  91 FPFvprfddesrdSRRYPS---HREVLAYLQDFAREFKIEEMVRFETEV--VRVEP---VDGKWRVQSKnSGGFSKDEIF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 142 DGVMVCSGHYTE---KYLPlqdfaGISKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRrg 218
Cdd:PLN02172 163 DAVVVCNGHYTEpnvAHIP-----GIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASR-- 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 219 twiwnrvwdngdpldialfTRYNRTVKSFyPTFLINRWTENKLNlrfnhanyglqakhrfLSHQsifsddlpnriisgrv 298
Cdd:PLN02172 236 -------------------ASESDTYEKL-PVPQNNLWMHSEID----------------TAHE---------------- 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758 299 lvktnvreftSTSAIFEDGSEEIVDVVVFATGYTLSFPFLDDSSEI-LDSKHT--MFKFVFPPQLeKPTLAFIGiLQPIG 375
Cdd:PLN02172 264 ----------DGSIVFKNGKVVYADTIVHCTGYKYHFPFLETNGYMrIDENRVepLYKHVFPPAL-APGLSFIG-LPAMG 331

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256221758 376 ATIPTSELQSRWVTRVFAGLQKLPSQSNMMADINRKKRKMEKeFVKSPRDVRRVPYI--DYMDEIASEIGVKP 446
Cdd:PLN02172 332 IQFVMFEIQSKWVAAVLSGRVTLPSEDKMMEDINAWYASLEA-LGIPKRYTHKLGKIqsEYLNWIAEECGCPL 403
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
90-348 1.03e-12

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 68.79  E-value: 1.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   90 EYLRMYARHFGLmkHIQFQTRV-CVVRKRPDFsssgqwdvVVEADGKQknYIFDGVMVCSGHYtekylplqDFAGISKFQ 168
Cdd:pfam13738  79 EYLRRVADHFEL--PINLFEEVtSVKKEDDGF--------VVTTSKGT--YQARYVIIATGEF--------DFPNKLGVP 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  169 GSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRRGtwiwnrVWDNGDpldialfTRYNRTVKsfy 248
Cdd:pfam13738 139 ELPKHYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGS------EWEDRD-------SDPSYSLS--- 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  249 PtflinrWTENklnlRFNHAnyglqakhrfLSHQSIfsddlpnriisgRVLVKTNVREFTSTSAI----FEDGSEEIV-D 323
Cdd:pfam13738 203 P------DTLN----RLEEL----------VKNGKI------------KAHFNAEVKEITEVDVSykvhTEDGRKVTSnD 250

                         250       260
                  ....*....|....*....|....*
gi 256221758  324 VVVFATGYTLSFPFLDDSSEILDSK 348
Cdd:pfam13738 251 DPILATGYHPDLSFLKKGLFELDED 275
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
6-217 8.19e-08

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 53.97  E-value: 8.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   6 IAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNdIGG-LWRYKETpENGrPGIYKSLTCntskemttfsdypiPDhypnymh 84
Cdd:COG0492    3 VVIIGAGPAGLTAAIYAARAGLKTLVIEGGE-PGGqLATTKEI-ENY-PGFPEGISG--------------PE------- 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  85 hskMMEYLRMYARHFGLmkHIQFQTRVCVVRKRPDFsssgqwdVVVEADGKQknYIFDGVMVCSGhYTEKYLPLqdfAGI 164
Cdd:COG0492   59 ---LAERLREQAERFGA--EILLEEVTSVDKDDGPF-------RVTTDDGTE--YEAKAVIIATG-AGPRKLGL---PGE 120

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 256221758 165 SKFQGSCLHSWEYKHPDSFVGKRVVVIGIGNSGADVANEISCVTEQVFLSTRR 217
Cdd:COG0492  121 EEFEGRGVSYCATCDGFFFRGKDVVVVGGGDSALEEALYLTKFASKVTLIHRR 173
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 4-207 1.98e-06

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 50.16  E-value: 1.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYketpengrpGIyksltcntskemttfsdypipdhyPNYm 83
Cdd:PRK12810 144 KKVAVVGSGPAGLAAADQLARAGHKVTVFERADRIGGLLRY---------GI------------------------PDF- 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  84 hhsKM-MEYLRmyaRHFGLMKH--IQFQTRVCVVRkrpdfsssgqwDVVVEADGKQknyiFDGVMVCSGHYTEKYLPL-- 158
Cdd:PRK12810 190 ---KLeKEVID---RRIELMEAegIEFRTNVEVGK-----------DITAEELLAE----YDAVFLGTGAYKPRDLGIpg 248

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256221758 159 QDFAGIskfqgsclH--------------SWEYKHPDSFVGKRVVVIGIGNSGADvaneisCV 207
Cdd:PRK12810 249 RDLDGV--------HfamdfliqntrrvlGDETEPFISAKGKHVVVIGGGDTGMD------CV 297
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 90-331 9.07e-06

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 47.97  E-value: 9.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   90 EYLRMYARHFGlmKHIQFQTRVCVVRKRPDfSSSGQWDVVVE-ADGKQKNYIFDGVMVCSGhyTEKYLPlQDFAGiskfQ 168
Cdd:pfam13434  99 DYLQWAASHLP--NRLRFGQEVESVEPDAE-RGEPLLRVRVRdADGEETTFLARNLVLGTG--GEPYIP-ECARG----G 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  169 GSCLHSWEY--KHPDSFVGKRVVVIGIGNSGADvaneiscvteqvflstrrgtwIWNRVWDNGDPLDIALFTRYNRtvks 246
Cdd:pfam13434 169 ERVFHSSEYleRIDRLAAKKRIAVVGSGQSAAE---------------------IFRDLLRRGPAYELTWVTRSPN---- 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  247 FYP---TFLINRWT-------------ENKLNL--RFNHANYG------LQAKHRFLSHQSIfSDDLPNRIISGRVLV-- 300
Cdd:pfam13434 224 FFPlddSPFVNEIFspeyvdyfyslpeDTRRALlrEQKGTNYDgidpslIEEIYRLLYEQRV-DGDPRHRLLPNREVQsa 302

                         250       260       270
                  ....*....|....*....|....*....|....
gi 256221758  301 -KTNVREFTSTSAIFEDGSEE--IVDVVVFATGY 331
Cdd:pfam13434 303 eRVGDGGVELTLRDGEQGREEtlETDVVVLATGY 336
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
7-150 3.43e-05

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 44.19  E-value: 3.43e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758    7 AIIGAGVSGLGA----IKSCLEEGLEPTCFEKSND-IGGLWRYKETPEngrpgiyksLTCNT-SKEMTTFSDypIPDHYP 80
Cdd:pfam13454   1 AIVGGGPSGLALlerlLARAPKRPLEITLFDPSPPgAGGVYRTDQSPE---------HLLNVpASRMSLFPD--DPPHFL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   81 NYMHHSKMM------------------EYLRMYARHFGL----MKHIQF-QTRVCVVRKRPDfsssGQWdvVVEADGKQk 137
Cdd:pfam13454  70 EWLRARGALdeapgldpddfppralygRYLRDRFEEALArapaGVTVRVhRARVTDLRPRGD----GYR--VLLADGRT- 142

                         170
                  ....*....|...
gi 256221758  138 nYIFDGVMVCSGH 150
Cdd:pfam13454 143 -LAADAVVLATGH 154
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-40 5.79e-05

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 45.25  E-value: 5.79e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 256221758   1 MEVKQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGG 40
Cdd:COG3380    1 MSMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGG 40
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-50 8.08e-05

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 40.59  E-value: 8.08e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 256221758    8 IIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPEN 50
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGY 43
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 4-41 9.70e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 44.82  E-value: 9.70e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 256221758   4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGL 41
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGL 39
PRK07233 PRK07233
hypothetical protein; Provisional
 6-41 1.13e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 44.49  E-value: 1.13e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 256221758   6 IAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGL 41
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGL 37
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
6-201 5.08e-04

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 42.63  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758   6 IAIIGAGVSGLGAIKSCLEEGLEP---TCFEKSNDIGglwryketpengrPGI-Y----KSLTCNT-SKEMTTFSDYpiP 76
Cdd:COG4529    8 IAIIGGGASGTALAIHLLRRAPEPlriTLFEPRPELG-------------RGVaYstdsPEHLLNVpAGRMSAFPDD--P 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256221758  77 DHYPNYMHHSKMM-----------------EYLR----MYARHFGLMKHIQF-QTRVCVVRKRpdfssSGQWDVVVeADG 134
Cdd:COG4529   73 DHFLRWLRENGARaapaidpdafvprrlfgEYLRerlaEALARAPAGVRLRHiRAEVVDLERD-----DGGYRVTL-ADG 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256221758 135 KQknYIFDGVMVCSGHytekyLPLQDFAGISKFQGSCLHS-WEYKHPDSF-VGKRVVVIGIGNSGADVA 201
Cdd:COG4529  147 ET--LRADAVVLATGH-----PPPAPPPGLAAGSPRYIADpWPPGALARIpPDARVLIIGTGLTAIDVV 208
PRK07208 PRK07208
hypothetical protein; Provisional
 1-51 6.52e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 42.18  E-value: 6.52e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 256221758   1 MEVKQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRykeTPENG 51
Cdd:PRK07208   2 TNKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISR---TVTYK 49
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 4-44 4.47e-03

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 39.71  E-value: 4.47e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 256221758   4 KQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRY 44
Cdd:PRK12814 194 KKVAIIGAGPAGLTAAYYLLRKGHDVTIFDANEQAGGMMRY 234
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-54 4.66e-03

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 39.45  E-value: 4.66e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 256221758   1 MEVKQIAIIGAGVSGLGAIKSCLEEGLEPTCFEKSNDIGGLWRYKETPENGRPG 54
Cdd:COG3349    1 MMPPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGGRARSFPDPDTGLPI 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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