|
Name |
Accession |
Description |
Interval |
E-value |
| GT4_ALG11-like |
cd03806 |
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related ... |
62-486 |
0e+00 |
|
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides.
Pssm-ID: 340835 [Multi-domain] Cd Length: 419 Bit Score: 733.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 62 AVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNIRLPRPVKFVF-LKHRLLVEAK 140
Cdd:cd03806 2 TVGFFHPYCNAGGGGERVLWCAVKATQKAYPNNICVIYTGDTDSSPEEILEKVESRFNIDLDSPRIVFFlLKYRKLVEAK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 141 LYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADY 220
Cdd:cd03806 82 TYPRFTLLGQALGSMILGFEALLKLVPDVFIDTMGYPFTYPLVRLLGGCPVVAYVHYPTISTDMLNKVRSREASYNNDST 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 221 ISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIgedneeKEQK 300
Cdd:cd03806 162 IARSSVLSIAKLLYYRLFAFLYGLAGSFADVVMVNSTWTYNHIRQLWKRNIKPSIVYPPCDTEELTKLPI------DEKT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 301 KCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPagREAVKLVLIGGCRNQEDEDRVLMLRGLCQELGIADRVEFKLNI 380
Cdd:cd03806 236 RENQILSIAQFRPEKNHPLQLRAFAELLKRLPESI--RSNPKLVLIGSCRNEEDKERVEALKLLAKELILEDSVEFVVDA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 381 PFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGGPTGFLADDEDNYADAMERILSMS 460
Cdd:cd03806 314 PYEELKELLSTASIGLHTMWNEHFGIGVVEYMAAGLIPLAHASAGPLLDIVVPWDGGPTGFLASTPEEYAEAIEKILTLS 393
|
410 420
....*....|....*....|....*.
gi 238624126 461 PATRLEMRRRARLSVSRFSDQEFEGS 486
Cdd:cd03806 394 EEERLQRREAARSSAERFSDEEFERD 419
|
|
| PLN02949 |
PLN02949 |
transferase, transferring glycosyl groups |
26-496 |
0e+00 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215511 [Multi-domain] Cd Length: 463 Bit Score: 561.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 26 FYLSFLLTTILFLFIMGVRSWLQMKRKTRRvqdgrpAVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGV 105
Cdd:PLN02949 5 LILYHLLTSIVLLLVAIALSVLRARRSRKR------AVGFFHPYTNDGGGGERVLWCAVRAIQEENPDLDCVIYTGDHDA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 106 TAEEILDGARRRFNIRLPRPVKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFRy 185
Cdd:PLN02949 79 SPDSLAARARDRFGVELLSPPKVVHLRKRKWIEEETYPRFTMIGQSLGSVYLAWEALCKFTPLYFFDTSGYAFTYPLAR- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 186 LGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILA 265
Cdd:PLN02949 158 LFGCKVVCYTHYPTISSDMISRVRDRSSMYNNDASIARSFWLSTCKILYYRAFAWMYGLVGRCAHLAMVNSSWTKSHIEA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 266 LWRTPNRTSVVYPPCDVQAFLDVPIgEDNEEKEQkkchsLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPagrEAVKLVL 345
Cdd:PLN02949 238 LWRIPERIKRVYPPCDTSGLQALPL-ERSEDPPY-----IISVAQFRPEKAHALQLEAFALALEKLDADV---PRPKLQF 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 346 IGGCRNQEDEDRVLMLRGLCQELGIADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGG 425
Cdd:PLN02949 309 VGSCRNKEDEERLQKLKDRAKELGLDGDVEFHKNVSYRDLVRLLGGAVAGLHSMIDEHFGISVVEYMAAGAVPIAHNSAG 388
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 238624126 426 PKLDIVVPYDGGPTGFLADDEDNYADAMERILSMSPATRLEMRRRARLSVSRFSDQEFEGSFLSAMEPLMS 496
Cdd:PLN02949 389 PKMDIVLDEDGQQTGFLATTVEEYADAILEVLRMRETERLEIAAAARKRANRFSEQRFNEDFKDAIRPILN 459
|
|
| ALG11_N |
pfam15924 |
ALG11 mannosyltransferase N-terminus; |
60-267 |
3.01e-142 |
|
ALG11 mannosyltransferase N-terminus;
Pssm-ID: 464944 Cd Length: 209 Bit Score: 406.86 E-value: 3.01e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 60 RPAVAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNIRLPR-PVKFVFLKHRLLVE 138
Cdd:pfam15924 1 KGIVGFFHPYCNAGGGGERVLWCAVRATQRRYPNAICVVYTGDIDASKEEILAKVKSRFNIELDPsRIVFVYLRKRKLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 139 AKLYPHFTLLGQSVGSIFLGWEALTEFVPDLYIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNA 218
Cdd:pfam15924 81 ASTYPRFTLLGQSLGSIILAWEALSKLVPDVFIDTMGYAFTYPLVRLLGGCPVGAYVHYPTISTDMLSRVSSREAGYNND 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 238624126 219 DYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALW 267
Cdd:pfam15924 161 SAIASSGLLSKAKLIYYRLFALLYGLVGSFADVVMVNSSWTQNHIRSLW 209
|
|
| GT4_ALG2-like |
cd03805 |
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ... |
63-487 |
4.53e-36 |
|
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.
Pssm-ID: 340834 [Multi-domain] Cd Length: 392 Bit Score: 138.11 E-value: 4.53e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 63 VAFFHPYCnaG-GGGERVLWCALRALQNRYQDVSFvvYTG--DQGVTAEEILDGarrRFNIR-----LPRpvkfvflkhr 134
Cdd:cd03805 3 VAFLHPDL--GiGGAERLVVDAALALQSRGHEVTI--YTShhDPSHCFEETKDG---TLPVRvrgdwLPR---------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 135 llveaKLYPHFTLLGQSVGSIFLGWEALTEFV--PDLYI-DSMgfAFTLPVFRYLGGCQVGSYVHYPtistDMLSVVREr 211
Cdd:cd03805 66 -----SIFGRFHALCAYLRMLYLALYLLLFSGekYDVFIvDQV--SACVPLLKLFRPSKILFYCHFP----DQLLAQRK- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 212 nprfnnadyissnpvlSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHIL----ALWRTPNRtsVVYPPCDVQAFLD 287
Cdd:cd03805 134 ----------------SLLKRLYRKPFDWLEEFTTGMADQIVVNSNFTAGVFKktfpSLAKNPPE--VLYPCVDTDSFDS 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 288 VPIGEDNEEKEQKKC-HSLVSVGQFRPEKDHQLQIRAFKKLLDRKEvepaGREAVKLVLIGGC--RNQEDEDRVLMLRGL 364
Cdd:cd03805 196 TSEDPDPGDLIAKSNkKFFLSINRFERKKNIALAIEAFAKLKQKLP----EFENVRLVIAGGYdpRVAENVEYLEELQRL 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 365 CQEL-GIADRVEFKLNIPfQELKKDLTDATIG-LHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVpydgGPTGFL 442
Cdd:cd03805 272 AEELlNVEDQVLFLRSIS-DSQKEQLLSSALAlLYTPSNEHFGIVPLEAMYAGKPVIACNSGGPLETVVE----GVTGFL 346
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 238624126 443 AD-DEDNYADAMERILSMsPATRLEMRRRARLSVS-RFSDQEFEGSF 487
Cdd:cd03805 347 CEpTPEAFAEAMLKLAND-PDLADRMGAAGRKRVKeKFSREAFAERL 392
|
|
| Glycos_transf_1 |
pfam00534 |
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ... |
305-472 |
2.72e-27 |
|
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
Pssm-ID: 425737 [Multi-domain] Cd Length: 158 Bit Score: 107.36 E-value: 2.72e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 305 LVSVGQFRPEKDHQLQIRAFKKLLDRKEVepagreaVKLVLIGgcrNQEDEDRvlmLRGLCQELGIADRVEFKLNIPFQE 384
Cdd:pfam00534 5 ILFVGRLEPEKGLDLLIKAFALLKEKNPN-------LKLVIAG---DGEEEKR---LKKLAEKLGLGDNVIFLGFVSDED 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 385 LKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPYDggpTGFLAD--DEDNYADAMERILSmSPA 462
Cdd:pfam00534 72 LPELLKIADVFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPP-EVVKDGE---TGFLVKpnNAEALAEAIDKLLE-DEE 146
|
170
....*....|
gi 238624126 463 TRLEMRRRAR 472
Cdd:pfam00534 147 LRERLGENAR 156
|
|
| GT4_PimA-like |
cd03801 |
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
63-479 |
1.46e-23 |
|
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 101.85 E-value: 1.46e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 63 VAFFHPYCNAG-GGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEIldgarRRFNIRLPRPVKFVFLKHRLLVEAKL 141
Cdd:cd03801 2 ILLLSPELPPPvGGAERHVRELARALAARGHDVTVLTPADPGEPPEELE-----DGVIVPLLPSLAALLRARRLLRELRP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 142 YPHFtllgqsvgsiflgwealteFVPDL-YIDSMGFAFTLPVFRYLGGCQVGSYVHYPTistdmlsvvrernPRFNNADY 220
Cdd:cd03801 77 LLRL-------------------RKFDVvHAHGLLAALLAALLALLLGAPLVVTLHGAE-------------PGRLLLLL 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 221 ISSNPVLSAIKVIYYCVfallyglagscsDVIMVNSTWTLGHILAL-WRTPNRTSVVYPPCDVQAFlDVPIGEDNEEKEQ 299
Cdd:cd03801 125 AAERRLLARAEALLRRA------------DAVIAVSEALRDELRALgGIPPEKIVVIPNGVDLERF-SPPLRRKLGIPPD 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 300 KKchSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGgcRNQEDEDRVLMLrglcqELGIADRVEFKLN 379
Cdd:cd03801 192 RP--VLLFVGRLSPRKGVDLLLEALAKLLRR-------GPDVRLVIVG--GDGPLRAELEEL-----ELGLGDRVRFLGF 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 380 IPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLA--DDEDNYADAMERIL 457
Cdd:cd03801 256 VPDEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLP-EVVED---GEGGLVVppDDVEALADALLRLL 331
|
410 420
....*....|....*....|...
gi 238624126 458 SmSPATRLEMRRRARLSVS-RFS 479
Cdd:cd03801 332 A-DPELRARLGRAARERVAeRFS 353
|
|
| GT4_GT28_WabH-like |
cd03811 |
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ... |
63-484 |
3.57e-22 |
|
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.
Pssm-ID: 340839 [Multi-domain] Cd Length: 351 Bit Score: 97.81 E-value: 3.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 63 VAFFHPyCNAGGGGERVLWCALRALQNRYQDVSFVVYTGdqgvtaEEILDGARRRFNIRLPRPVKFVFLKHRLLVEAKLY 142
Cdd:cd03811 2 ILFVIP-SLSGGGAERVLLNLANALDKRGYDVTLVLLRD------EGDLDKQLNGDVKLIRLLIRVLKLIKLGLLKAILK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 143 phftllgqsVGSIFLgwealtEFVPDLYIDSMGFAFTLPVFRYLGGCQVgsyvhyptistdmlsVVRERNPRFNNadYIS 222
Cdd:cd03811 75 ---------LKRILK------RAKPDVVISFLGFATYIVAKLAAARSKV---------------IAWIHSSLSKL--YYL 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 223 SNPVLSAIKVIYYCvfallyglagscsDVIMVNSTWTLGHILAL-WRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKK 301
Cdd:cd03811 123 KKKLLLKLKLYKKA-------------DKIVCVSKGIKEDLIRLgPSPPEKIEVIYNPIDIDRIRALAKEPILNEPEDGP 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 302 chSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGgcrNQEDEDRvlmLRGLCQELGIADRVEF---KL 378
Cdd:cd03811 190 --VILAVGRLDPQKGHDLLIEAFAKLRKK-------YPDVKLVILG---DGPLREE---LEKLAKELGLAERVIFlgfQS 254
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 379 NiPFQELKKdltdATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpyDGGPTGFLADDEDNYADAMERILS 458
Cdd:cd03811 255 N-PYPYLKK----ADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPR-EIL---DDGENGLLVPDGDAAALAGILAAL 325
|
410 420
....*....|....*....|....*.
gi 238624126 459 MSPATRLEMRRRARLSVSRFSDQEFE 484
Cdd:cd03811 326 LQKKLDAALRERLAKAQEAVFREYTI 351
|
|
| GT4_sucrose_synthase |
cd03800 |
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ... |
244-478 |
2.04e-19 |
|
sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.
Pssm-ID: 340830 [Multi-domain] Cd Length: 398 Bit Score: 89.99 E-value: 2.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 244 LAGSCSDVIMVNSTWTLGHILALWRT-PNRTSVVYPPCDVQAFldVPIGEDNEE-----KEQKKcHSLVSVGQFRPEKDH 317
Cdd:cd03800 159 QILEAADRVIASTPQEADELISLYGAdPSRINVVPPGVDLERF--FPVDRAEARrarllLPPDK-PVVLALGRLDPRKGI 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 318 QLQIRAFKKLLDRkevepagREAVKLVLIGGCRNQEDEDRVLMLRGLCQELGIADRVEFKLNIPFQELKKDLTDATIGLH 397
Cdd:cd03800 236 DTLVRAFAQLPEL-------RELANLVLVGGPSDDPLSMDREELAELAEELGLIDRVRFPGRVSRDDLPELYRAADVFVV 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 398 TMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLAD--DEDNYADAMERILsMSPATRLEMRRRARLSV 475
Cdd:cd03800 309 PSLYEPFGLTAIEAMACGTPVVATAVGGLQ-DIVRD---GRTGLLVDphDPEALAAALRRLL-DDPALWQRLSRAGLERA 383
|
...
gi 238624126 476 SRF 478
Cdd:cd03800 384 RAH 386
|
|
| GT4_WlbH-like |
cd03798 |
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ... |
306-483 |
5.70e-18 |
|
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.
Pssm-ID: 340828 [Multi-domain] Cd Length: 376 Bit Score: 85.51 E-value: 5.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 306 VSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGgcrNQEDEDRvlmLRGLCQELGIADRVEFKLNIPFQEL 385
Cdd:cd03798 204 LFVGRLIPRKGIDLLLEAFARLAKA-------RPDVVLLIVG---DGPLREA---LRALAEDLGLGDRVTFTGRLPHEQV 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 386 KKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpyDGGPTGFLAD--DEDNYADAMERILsMSPAT 463
Cdd:cd03798 271 PAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIP-EVV---GDPETGLLVPpgDADALAAALRRAL-AEPYL 345
|
170 180
....*....|....*....|
gi 238624126 464 RLEMRRRARLSVSRFSDQEF 483
Cdd:cd03798 346 RELGEAARARVAERFSWVKA 365
|
|
| GT4_MtfB-like |
cd03809 |
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
248-479 |
3.58e-16 |
|
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.
Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 80.10 E-value: 3.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 248 CSDVIMVNSTWTLGHILALWRTP-NRTSVVYPPCDVQAFLDVPIGEDNEEKEQKkCHSLVSVGQFRPEKDHQLQIRAFKK 326
Cdd:cd03809 138 RADAIITVSEATRDDIIKFYGVPpEKIVVIPLGVDPSFFPPESAAVLIAKYLLP-EPYFLYVGTLEPRKNHERLLKAFAL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 327 LLDRKEVepagreaVKLVLIGGcrnqeDEDRVLMLRGLCQELGIADRVEFKLNIPFQELKKDLTDATI----GLHtmwnE 402
Cdd:cd03809 217 LKKQGGD-------LKLVIVGG-----KGWEDEELLDLVKKLGLGGRVRFLGYVSDEDLPALYRGARAfvfpSLY----E 280
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238624126 403 HFGIGIVECMAAGTIILAhkSGGPKLDIVVpydgGPTGFLAD--DEDNYADAMERILSmSPATRLEMRRRARLSVSRFS 479
Cdd:cd03809 281 GFGLPVLEAMACGTPVIA--SNISVLPEVA----GDAALYFDplDPESIADAILRLLE-DPSLREELIRKGLERAKKFS 352
|
|
| GT4_UGDG-like |
cd03817 |
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ... |
275-479 |
2.10e-14 |
|
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.
Pssm-ID: 340844 [Multi-domain] Cd Length: 372 Bit Score: 74.62 E-value: 2.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 275 VVYPPCDVQAFLDVPIGEDNEE---KEQKKchSLVSVGQFRPEKDHQLQIRAFKKLLDRKEvepagreaVKLVLIG-GCR 350
Cdd:cd03817 173 VIPNGIDLDKFEKPLNTEERRKlglPPDEP--ILLYVGRLAKEKNIDFLLRAFAELKKEPN--------IKLVIVGdGPE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 351 NQEdedrvlmLRGLCQELGIADRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDI 430
Cdd:cd03817 243 REE-------LKELARELGLADKVIFTGFVPREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVVAAKDPAAS-EL 314
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 238624126 431 VvpyDGGPTGFL-ADDEDNYADAMERILSMsPATRLEMRRRARLSVSRFS 479
Cdd:cd03817 315 V---EDGENGFLfEPNDETLAEKLLHLREN-LELLRKLSKNAEISAREFA 360
|
|
| GT4_WbnK-like |
cd03807 |
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ... |
305-479 |
1.73e-13 |
|
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.
Pssm-ID: 340836 [Multi-domain] Cd Length: 362 Bit Score: 71.58 E-value: 1.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 305 LVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIG-GCRNQEDEdrvLMLRglcqELGIADRVEFKLNIpfQ 383
Cdd:cd03807 193 IGIVGRLHPVKDHSDLLRAAALLVET-------HPDLRLLLVGrGPERPNLE---RLLL----ELGLEDRVHLLGER--S 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 384 ELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGpKLDIVVPydggPTGFL--ADDEDNYADAMERILSMsP 461
Cdd:cd03807 257 DVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGG-AAELVDD----GTGFLvpAGDPQALADAIRALLED-P 330
|
170
....*....|....*....
gi 238624126 462 ATRLEMRRRARLSV-SRFS 479
Cdd:cd03807 331 EKRARLGRAARERIaNEFS 349
|
|
| Glycosyltransferase_GTB-type |
cd01635 |
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
250-437 |
1.29e-12 |
|
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340816 [Multi-domain] Cd Length: 235 Bit Score: 67.43 E-value: 1.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 250 DVIMVNSTW--TLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKL 327
Cdd:cd01635 56 DVVHAHSPHaaALAALLAARLLGIPIVVTVHGPDSLESTRSELLALARLLVSLPLADKVSVGRLVPEKGIDLLLEALALL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 328 ldrkevePAGREAVKLVLIGGCRNQEDEDRVLmlrglcQELGIADRVEFKLNIPFQELKKDLT-DATIGLHTMWNEHFGI 406
Cdd:cd01635 136 -------KARLPDLVLVLVGGGGEREEEEALA------AALGLLERVVIIGGLVDDEVLELLLaAADVFVLPSRSEGFGL 202
|
170 180 190
....*....|....*....|....*....|.
gi 238624126 407 GIVECMAAGTIILAHKSGGPKLDIVVPYDGG 437
Cdd:cd01635 203 VLLEAMAAGKPVIATDVGGIPEFVVDGENGL 233
|
|
| GT4_AviGT4-like |
cd03802 |
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ... |
265-481 |
2.94e-12 |
|
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.
Pssm-ID: 340832 [Multi-domain] Cd Length: 333 Bit Score: 67.70 E-value: 2.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 265 ALWRTPNRTSVVYPPCDVQAFLDVPIGEDNeekeqkkchsLVSVGQFRPEKDHQLQIRAFKKlldrkevepAGReavKLV 344
Cdd:cd03802 142 AATPPIDYLTVVHNGLDPADYRFQPDPEDY----------LAFLGRIAPEKGLEDAIRVARR---------AGL---PLK 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 345 LIGGCRNQEDEDRVlmlrglcQELGIADRVEFKLNIPFQELKKDLTDATIGLHT-MWNEHFGIGIVECMAAGTIILAHKS 423
Cdd:cd03802 200 IAGKVRDEDYFYYL-------QEPLPGPRIEFIGEVGHDEKQELLGGARALLFPiNWDEPFGLVMIEAMACGTPVIAYRR 272
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 424 GGPkLDIVVPydgGPTGFLADDEDNYADAMERILSMSPATrleMRRRA--RLSVSRFSDQ 481
Cdd:cd03802 273 GGL-PEVIQH---GETGFLVDSVEEMAEAIANIDRIDRAA---CRRYAedRFSAARMADR 325
|
|
| GT4_WbaZ-like |
cd03804 |
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ... |
250-487 |
1.72e-11 |
|
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.
Pssm-ID: 340833 [Multi-domain] Cd Length: 356 Bit Score: 65.38 E-value: 1.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 250 DVIMVNSTWTLGHIlalWRTPNRTS-VVYPPCDVQAFLDVPIGEDneekeqkkchSLVSVGQFRPEKDHQLQIRAFKKLl 328
Cdd:cd03804 159 DLFIANSQFVARRI---KKFYGREStVIYPPVDTDAFAPAADKED----------YYLTASRLVPYKRIDLAVEAFNEL- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 329 drkevepaGReavKLVLIGgcrNQEDEDRvlmLRGlcqelgIADR-VEFKLNIPFQELKKDLTDATiGLHTMWNEHFGIG 407
Cdd:cd03804 225 --------PK---RLVVIG---DGPDLDR---LRA------MASPnVEFLGYQPDEVLKELLSKAR-AFVFAAEEDFGIV 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 408 IVECMAAGTIILAHKSGGpKLDIVVPydgGPTGFLADDEDNYA--DAMERILSMSPATRLEmrrRARLSVSRFSDQEFEG 485
Cdd:cd03804 281 PVEAQACGTPVIAFGKGG-ALETVRP---GPTGILFGEQTVESlkAAVEEFEQNFDRFKPQ---AIRANAERFSRARFRQ 353
|
..
gi 238624126 486 SF 487
Cdd:cd03804 354 EI 355
|
|
| GT4_AmsD-like |
cd03820 |
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ... |
63-479 |
2.13e-11 |
|
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.
Pssm-ID: 340847 [Multi-domain] Cd Length: 351 Bit Score: 65.34 E-value: 2.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 63 VAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEildgarrrfnirLPRPVKFVFLKHRLLVEAKLY 142
Cdd:cd03820 2 IAIVIPSISNAGGAERVAINLANHLAKKGYDVTIISLDSAEKPPFYE------------LDDNIKIKNLGDRKYSHFKLL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 143 PHFtllgQSVGSIFLgwEALTEFVPDLYIDSMGFAFTLPvfrylggcqvgsyvhyPTISTDMLSVVRERNPRFNNADYIS 222
Cdd:cd03820 70 LKY----FKKVRRLR--KYLKNNKPDVVISFRTSLLTFL----------------ALIGLKSKLIVWEHNNYEAYNKGLR 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 223 SnpvlsaikviyYCVFALLYGLAgscsDVIMVNSTWTLghILALWRTPNRTSVVYPPCDvqaFLDVPIGEDNEEKeqkkc 302
Cdd:cd03820 128 R-----------LLLRRLLYKRA----DKIVVLTEADK--LKKYKQPNSNVVVIPNPLS---FPSEEPSTNLKSK----- 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 303 hSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGGCrnqEDEDRvlmLRGLCQELGIADRVEFKLNIpf 382
Cdd:cd03820 183 -RILAVGRLTYQKGFDLLIEAWALIAKK-------HPDWKLRIYGDG---PEREE---LEKLIDKLGLEDRVKLLGPT-- 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 383 QELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKS-GGPKlDIVvpyDGGPTGFLADDED--NYADAMERILSm 459
Cdd:cd03820 247 KNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCpTGPS-EII---EDGENGLLVPNGDvdALAEALLRLME- 321
|
410 420
....*....|....*....|
gi 238624126 460 SPATRLEMRRRARLSVSRFS 479
Cdd:cd03820 322 DEELRKKMGKNARKNAERFS 341
|
|
| RfaB |
COG0438 |
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ... |
389-496 |
7.15e-11 |
|
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440207 [Multi-domain] Cd Length: 123 Bit Score: 59.62 E-value: 7.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 389 LTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLAD--DEDNYADAMERILSmSPATRLE 466
Cdd:COG0438 18 LAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLP-EVIED---GETGLLVPpgDPEALAEAILRLLE-DPELRRR 92
|
90 100 110
....*....|....*....|....*....|.
gi 238624126 467 MRRRAR-LSVSRFSDQEFEGSFLSAMEPLMS 496
Cdd:COG0438 93 LGEAAReRAEERFSWEAIAERLLALYEELLA 123
|
|
| Glyco_trans_1_4 |
pfam13692 |
Glycosyl transferases group 1; |
305-458 |
1.92e-10 |
|
Glycosyl transferases group 1;
Pssm-ID: 463957 [Multi-domain] Cd Length: 138 Bit Score: 58.68 E-value: 1.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 305 LVSVGQFRPE-KDHQLQIRAFKKLLDRkevepagREAVKLVLIGGCRNQEDEDRVLmlrglcqelGIADRVEFklnIPF- 382
Cdd:pfam13692 4 ILFVGRLHPNvKGVDYLLEAVPLLRKR-------DNDVRLVIVGDGPEEELEELAA---------GLEDRVIF---TGFv 64
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 238624126 383 QELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVpydgGPTGFLA--DDEDNYADAMERILS 458
Cdd:pfam13692 65 EDLAELLAAADVFVLPSLYEGFGLKLLEAMAAGLPVVATDVGGIP-ELVD----GENGLLVppGDPEALAEAILRLLE 137
|
|
| GT4_CapM-like |
cd03808 |
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ... |
237-482 |
4.57e-10 |
|
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.
Pssm-ID: 340837 [Multi-domain] Cd Length: 358 Bit Score: 61.07 E-value: 4.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 237 VFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPIGEDNEEKEqkkcHSLVSVGQFRPEKD 316
Cdd:cd03808 128 LYLLLEKLALLFTDKVIFVNEDDRDLAIKKGIIKKKKTVLIPGSGVDLDRFQYSPESLPSEK----VVFLFVARLLKDKG 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 317 HQLQIRAFKKLLDRKevepagrEAVKLVLIGGCRnqEDEDRVLMLrglcQELGIADRVEF---KLNIPfqelkKDLTDAT 393
Cdd:cd03808 204 IDELIEAAKILKKKG-------PNVRFLLVGDGE--LENPSEILI----EKLGLEGRIEFlgfRSDVP-----ELLAESD 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 394 IGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVVPydgGPTGFLAD--DEDNYADAMERILSmSPATRLEMRRRA 471
Cdd:cd03808 266 VFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCR-ELVID---GVNGFLVPpgDVEALADAIEKLIE-DPELRKEMGEAA 340
|
250
....*....|..
gi 238624126 472 RLSV-SRFSDQE 482
Cdd:cd03808 341 RKRVeEKFDEEK 352
|
|
| GT4_BshA-like |
cd04962 |
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ... |
292-479 |
1.31e-09 |
|
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340859 [Multi-domain] Cd Length: 370 Bit Score: 59.67 E-value: 1.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 292 EDNEEKEQKKCHS----LVSVGQFRPEKDHQLQIRAFKKLldRKEVePAgreavKLVLIGgcrnqEDEDRVLMLRgLCQE 367
Cdd:cd04962 182 PAGALKRRLLAPPdekvVIHVSNFRPVKRIDDVVRVFARV--RRKI-PA-----KLLLVG-----DGPERVPAEE-LARE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 368 LGIADRVEFKLNIPfqELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGpkLDIVVpyDGGPTGFLAD--D 445
Cdd:cd04962 248 LGVEDRVLFLGKQD--DVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGG--IPEVV--KHGETGFLSDvgD 321
|
170 180 190
....*....|....*....|....*....|....*
gi 238624126 446 EDNYADAMERILSmSPATRLEMRRRARL-SVSRFS 479
Cdd:cd04962 322 VDAMAKSALSILE-DDELYNRMGRAARKrAAERFD 355
|
|
| GT4-like |
cd03814 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
305-492 |
8.78e-09 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.
Pssm-ID: 340842 [Multi-domain] Cd Length: 365 Bit Score: 57.30 E-value: 8.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 305 LVSVGQFRPEKDhqlqIRAFKKLLDRkevePAGREAVKLVLIGGCRNQEdedrVLMLRGLCQE-LGIADRvefklnipfQ 383
Cdd:cd03814 201 LLYVGRLAPEKN----LEALLDADLP----LAASPPVRLVVVGDGPARA----ELEARGPDVIfTGFLTG---------E 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 384 ELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpyDGGPTGFLAD--DEDNYADAMERiLSMSP 461
Cdd:cd03814 260 ELARAYASADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPR-DIV---RPGGTGALVEpgDAAAFAAALRA-LLEDP 334
|
170 180 190
....*....|....*....|....*....|.
gi 238624126 462 ATRLEMRRRARLSVSRFSDQEFEGSFLSAME 492
Cdd:cd03814 335 ELRRRMAARARAEAERYSWEAFLDNLLDYYA 365
|
|
| GT4_WavL-like |
cd03819 |
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ... |
308-473 |
4.07e-08 |
|
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.
Pssm-ID: 340846 [Multi-domain] Cd Length: 345 Bit Score: 55.05 E-value: 4.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 308 VGQFRPEKDHQLQIRAFKKLLDRKEVepagreavkLVLIGGCRNQEDEDRVLMlrglcQELGIADRVEFKLNIPfqELKK 387
Cdd:cd03819 188 VGRLSPEKGWLLLVDAAAELKDEPDF---------RLLVAGDGPERDEIRRLV-----ERLGLRDRVTFTGFRE--DVPA 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 388 DLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPkLDIVVPydgGPTGFLADDEDN--YADAMERiLSMSPATRL 465
Cdd:cd03819 252 ALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGA-REIVVH---GRTGLLVPPGDAeaLADAIRA-AKLLPEARE 326
|
....*...
gi 238624126 466 EMRRRARL 473
Cdd:cd03819 327 KLQAAAAL 334
|
|
| GT4_WbuB-like |
cd03794 |
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ... |
270-479 |
1.95e-07 |
|
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
Pssm-ID: 340825 [Multi-domain] Cd Length: 391 Bit Score: 53.11 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 270 PNRTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVepagreavKLVLIGGC 349
Cdd:cd03794 185 KEKIIVIPNWADLEEFKPPPKDELRKKLGLDDKFVVVYAGNIGKAQGLETLLEAAERLKRRPDI--------RFLFVGDG 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 350 RNQEDEDRVLMLRGLcqelgiaDRVEFKLNIPFQELKKDLTDATIGLHTMWNEHFGIGIV-----ECMAAGTIILAHKSG 424
Cdd:cd03794 257 DEKERLKELAKARGL-------DNVTFLGRVPKEEVPELLSAADVGLVPLKDNPANRGSSpsklfEYMAAGKPILASDDG 329
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 238624126 425 GPKLDIVVpydgGPTGFLADDEDN--YADAMERiLSMSPATRLEMRRRAR-LSVSRFS 479
Cdd:cd03794 330 GSDLAVEI----NGCGLVVEPGDPeaLADAILE-LLDDPELRRAMGENGReLAEEKFS 382
|
|
| GT4-like |
cd03813 |
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ... |
219-482 |
4.83e-07 |
|
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.
Pssm-ID: 340841 [Multi-domain] Cd Length: 474 Bit Score: 51.95 E-value: 4.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 219 DYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWTLGHILALWRTPNRTSVVYPPCDVQAFLDVPigednEEKE 298
Cdd:cd03813 215 EILQSTWIMGYIKKLWIRFFERLGKLAYQQADKIISLYEGNRRRQIRLGADPDKTRVIPNGIDIQRFAPAR-----EERP 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 299 QKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRkevepagREAVKLVLIGGcrNQEDEDRVLMLRGLCQELGIADRVEFkl 378
Cdd:cd03813 290 EKEPPVVGLVGRVVPIKDVKTFIRAFKLVRRA-------MPDAEGWLIGP--EDEDPEYAQECKRLVASLGLENKVKF-- 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 379 nIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKlDIVvpYDG----GPTGFL---ADDEDnYAD 451
Cdd:cd03813 359 -LGFQNIKEYYPKLGLLVLTSISEGQPLVILEAMASGVPVVATDVGSCR-ELI--YGAddalGQAGLVvppADPEA-LAE 433
|
250 260 270
....*....|....*....|....*....|.
gi 238624126 452 AMERILSmSPATRLEMRRRARLSVSRFSDQE 482
Cdd:cd03813 434 ALIKLLR-DPELRQAFGEAGRKRVEKYYTLE 463
|
|
| GT4_trehalose_phosphorylase |
cd03792 |
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ... |
277-477 |
1.94e-06 |
|
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.
Pssm-ID: 340823 [Multi-domain] Cd Length: 378 Bit Score: 50.01 E-value: 1.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 277 YPPCDVQAFLDVPIGEDNEEKeqkkchSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVepagreaVKLVLIGGcRNQEDED 356
Cdd:cd03792 178 LSPADIRYYLEKPFVIDPERP------YILQVARFDPSKDPLGVIDAYKLFKRRAEE-------PQLVICGH-GAVDDPE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 357 RVLMLRGLCQELGIADRVEF-KLNIPFQELKKDLTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVvpyd 435
Cdd:cd03792 244 GSVVYEEVMEYAGDDHDIHVlRLPPSDQEINALQRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVI---- 319
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 238624126 436 GGPTGFLADDEDNYADAMERILSmSPATRLEMRRRARLSVSR 477
Cdd:cd03792 320 DGETGFLVNSVEGAAVRILRLLT-DPELRRKMGLAAREHVRD 360
|
|
| GT4_GtfA-like |
cd04949 |
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ... |
297-480 |
6.04e-06 |
|
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340855 [Multi-domain] Cd Length: 328 Bit Score: 48.07 E-value: 6.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 297 KEQKKcHSLVSVGQFRPEKDHQLQIRAFKKLldRKEVePagreAVKLVLIGgcRNQEDEDrvlmLRGLCQELGIADRVEF 376
Cdd:cd04949 156 HERKS-NKIITISRLAPEKQLDHLIEAVAKA--VKKV-P----EITLDIYG--YGEEREK----LKKLIEELHLEDNVFL 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 377 K--LNIPFQELKkdltDATIGLHTMWNEHFGIGIVECMAAGTIILAHKsggpkldivVPYdgGPTGFLADDE-------- 446
Cdd:cd04949 222 KgyHSNLDQEYQ----DAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYD---------VKY--GPSELIEDGEngyliekn 286
|
170 180 190
....*....|....*....|....*....|....*.
gi 238624126 447 --DNYADAMERILSmSPATRLEMRRRARLSVSRFSD 480
Cdd:cd04949 287 niDALADKIIELLN-DPEKLQQFSEESYKIAEKYST 321
|
|
| GT4_ExpE7-like |
cd03823 |
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ... |
308-481 |
9.67e-06 |
|
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).
Pssm-ID: 340850 [Multi-domain] Cd Length: 357 Bit Score: 47.71 E-value: 9.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 308 VGQFRPEKDHQLQIRAFKKLlDRKEVEpagreavkLVLIGGCRNQEdedrvlmlrglCQELGIADRVEFKLNIPFQELKK 387
Cdd:cd03823 197 IGRLTEEKGIDLLVEAFKRL-PREDIE--------LVIAGHGPLSD-----------ERQIEGGRRIAFLGRVPTDDIKD 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 388 --DLTDATIgLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVvpydGGPTGFL--ADDEDNYADAMERI-----LS 458
Cdd:cd03823 257 fyEKIDVLV-VPSIWPEPFGLVVREAIAAGLPVIASDLGGIAELIQ----PGVNGLLfaPGDAEDLAAAMRRLltdpaLL 331
|
170 180
....*....|....*....|...
gi 238624126 459 MSPATRLEMRRRARLSVSRFSDQ 481
Cdd:cd03823 332 ERLRAGAEPPRSTESQAEEYLKL 354
|
|
| PLN02871 |
PLN02871 |
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase |
402-479 |
2.11e-05 |
|
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
Pssm-ID: 215469 [Multi-domain] Cd Length: 465 Bit Score: 47.01 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 402 EHFGIGIVECMAAGTIILAHKSGGPKlDIVVPYDGGPTGFLADDEDnYADAMERI--LSMSPATRLEMRRRARLSVSRFS 479
Cdd:PLN02871 342 ETLGFVVLEAMASGVPVVAARAGGIP-DIIPPDQEGKTGFLYTPGD-VDDCVEKLetLLADPELRERMGAAAREEVEKWD 419
|
|
| GT4_WbdM_like |
cd04951 |
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ... |
285-479 |
5.77e-05 |
|
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.
Pssm-ID: 340857 [Multi-domain] Cd Length: 360 Bit Score: 45.13 E-value: 5.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 285 FLDVPIGEDNEEKEQKKCHSL---------VSVGQFRPEKDHQLQIRAFKKLLDRKEvepagreAVKLVLIGgcrnqEDE 355
Cdd:cd04951 162 GIDLNKFKKDINVRLKIRNKLnlkndefviLNVGRLTEAKDYPNLLLAISELILSKN-------DFKLLIAG-----DGP 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 356 DRVLMLRGLCQeLGIADRVEFklnIPFQELKKDLTDAT--IGLHTMWnEHFGIGIVECMAAGTIILAHKSGGPKlDIVVP 433
Cdd:cd04951 230 LRNELERLICN-LNLVDRVIL---LGQISNISEYYNAAdlFVLSSEW-EGFGLVVAEAMACERPVVATDAGGVA-EVVGD 303
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 238624126 434 YDggptgFLADDEDNY--ADAMERILSMSPATRLEMRRRARLSVSRFS 479
Cdd:cd04951 304 HN-----YVVPVSDPQllAEKIKEIFDMSDEERDILGNKNEYIAKNFS 346
|
|
| GT4_Bme6-like |
cd03821 |
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ... |
305-479 |
6.90e-05 |
|
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.
Pssm-ID: 340848 [Multi-domain] Cd Length: 377 Bit Score: 45.05 E-value: 6.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 305 LVSVGQFRPEKDHQLQIRAFKKLLDrkevepAGREaVKLVLIGgcrnqEDEDRVLMLRGLCQELGIADRVEFKLNIPFQE 384
Cdd:cd03821 207 ILFLGRIHPKKGLDLLIRAARKLAE------QGRD-WHLVIAG-----PDDGAYPAFLQLQSSLGLGDRVTFTGPLYGEA 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 385 LKKDLTDATIGLHTMWNEHFGIGIVECMAAGT-IILAHKSGGPKLdivvpYDGGpTGFLADDEDNY-ADAMERILS--MS 460
Cdd:cd03821 275 KWALYASADLFVLPSYSENFGNVVAEALACGLpVVITDKCGLSEL-----VEAG-CGVVVDPNVSSlAEALAEALRdpAD 348
|
170
....*....|....*....
gi 238624126 461 PATRLEMRRRARLSVSRFS 479
Cdd:cd03821 349 RKRLGEMARRARQVEENFS 367
|
|
| GT4_WcaC-like |
cd03825 |
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ... |
375-481 |
3.32e-04 |
|
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.
Pssm-ID: 340851 [Multi-domain] Cd Length: 364 Bit Score: 42.70 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238624126 375 EFKLNIPFQELKKDLTDATIGLHTMWN-----------EHFGIGIVECMAAGTIILAHKSGGPkLDIVvpyDGGPTGFLA 443
Cdd:cd03825 236 PQIVILPFDIISLGYIDDDEQLVDIYSaadlfvhpslaDNLPNTLLEAMACGTPVVAFDTGGS-PEIV---QHGVTGYLV 311
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 238624126 444 DDED--NYADAMERILsMSPATRLEMRRRAR-LSVSRFSDQ 481
Cdd:cd03825 312 PPGDvqALAEAIEWLL-ANPKERESLGERARaLAENHFDQR 351
|
|
| GT5_Glycogen_synthase_DULL1-like |
cd03791 |
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 ... |
402-471 |
8.21e-03 |
|
Glycogen synthase GlgA and similar proteins; This family is most closely related to the GT5 family of glycosyltransferases. Glycogen synthase (EC:2.4.1.21) catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family includes starch synthases of plants, such as DULL1 in Zea mays and glycogen synthases of various organisms.
Pssm-ID: 340822 [Multi-domain] Cd Length: 474 Bit Score: 38.70 E-value: 8.21e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 238624126 402 EHFGIGIVECMAAGTIILAHKSGGPKlDIVVPYD---GGPTGFLADDEDNYA--DAMERILSM--SPATRLEMRRRA 471
Cdd:cd03791 379 EPCGLVQMYAMRYGTLPIVRRTGGLA-DTVFDYDpetGEGTGFVFEDYDAEAllAALRRALALyrNPELWRKLQKNA 454
|
|
| |
