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Conserved domains on  [gi|156071459|ref|NP_001143|]
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ADP/ATP translocase 2 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 7-296 5.05e-158

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 442.28  E-value: 5.05e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459   7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK--QYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 84
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459  85 QALNFAFKDKYKQIFlGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKaGAEREFRGLGDCLVKI 164
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGK-GGDREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459 165 YKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGML-PDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSG 243
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSG 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 156071459 244 RKGT-DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKK 296
Cdd:PTZ00169 244 RKAKsEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQK 297
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 7-296 5.05e-158

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 442.28  E-value: 5.05e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459   7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK--QYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 84
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459  85 QALNFAFKDKYKQIFlGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKaGAEREFRGLGDCLVKI 164
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGK-GGDREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459 165 YKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGML-PDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSG 243
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSG 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 156071459 244 RKGT-DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKK 296
Cdd:PTZ00169 244 RKAKsEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQK 297
Mito_carr pfam00153
Mitochondrial carrier protein;
6-101 1.36e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 105.43  E-value: 1.36e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459    6 VSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQitadKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQ 85
Cdd:pfam00153   3 LSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|....*.
gi 156071459   86 ALNFAFKDKYKQIFLG 101
Cdd:pfam00153  79 AIYFGTYETLKRLLLK 94
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 7-296 5.05e-158

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 442.28  E-value: 5.05e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459   7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK--QYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPT 84
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459  85 QALNFAFKDKYKQIFlGGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKaGAEREFRGLGDCLVKI 164
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGK-GGDREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459 165 YKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGML-PDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSG 243
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSG 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 156071459 244 RKGT-DIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKK 296
Cdd:PTZ00169 244 RKAKsEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQK 297
Mito_carr pfam00153
Mitochondrial carrier protein;
6-101 1.36e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 105.43  E-value: 1.36e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459    6 VSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQitadKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQ 85
Cdd:pfam00153   3 LSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|....*.
gi 156071459   86 ALNFAFKDKYKQIFLG 101
Cdd:pfam00153  79 AIYFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
109-206 8.84e-26

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 98.11  E-value: 8.84e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459  109 FWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAERefRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKG--RGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|....*...
gi 156071459  189 AAYFGIYDTAKGMLPDPK 206
Cdd:pfam00153  79 AIYFGTYETLKRLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
209-297 2.27e-17

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 75.77  E-value: 2.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459  209 HIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTdiMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV- 287
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKS--KGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIy 81

                          90
                  ....*....|
gi 156071459  288 LVLYDEIKKY 297
Cdd:pfam00153  82 FGTYETLKRL 91
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 116-271 7.99e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 37.21  E-value: 7.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459 116 NLASGGAAGATSLCFVYPLDFARTRLAADvgkagaerefrglgdclvKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIY 195
Cdd:PTZ00168   6 NLVTGALSGVIVDAVLYPIDSIKTNIQAK------------------KSFSFSDIKKLYSGILPTLVGTVPASAFFYCFY 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156071459 196 DTAKGMLPDpKNTHIVIS--WMIAQTVTAVAGLT-SYPFDTVRRRMMMqSGRkgtdimyTGTLDCWRKIARDEG-----G 267
Cdd:PTZ00168  68 ELSKKLLTE-YRENISKTnlYLISTSIAEITACIvRLPFEIVKQNMQV-SGN-------ISVLKTIYEITQREGlpsflG 138


                 ....
gi 156071459 268 KAFF 271
Cdd:PTZ00168 139 KSYF 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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