|
Name |
Accession |
Description |
Interval |
E-value |
| Importin_rep_6 |
pfam18829 |
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
761-870 |
3.30e-42 |
|
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry represents two consecutive repeat units and includes sequences captured by pfam18808.
:
Pssm-ID: 465881 Cd Length: 110 Bit Score: 149.56 E-value: 3.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 761 VLSEIMHSFAKCIELMGDGCLNNEHFEELGGILKAKLEEHFKNQEVRQAKRQDEDYDEQVEETLQDEDENDVYILTKVSD 840
Cdd:pfam18829 1 VLAEYYSSLAECIEVLGPNCLSDEQMEEFIKAINSNLTEYFERVKEREEERKDDDYDEEVEEDLEEEEETDEELLSEINK 80
|
90 100 110
....*....|....*....|....*....|
gi 224496028 841 ILHSIFSSYREKVLPWFEQLLQLIVNLICP 870
Cdd:pfam18829 81 AIHAIFKTHKTAFLPYFEQLLPTVVAFLND 110
|
|
| Importin_rep_4 |
pfam18808 |
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
264-353 |
1.19e-30 |
|
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit.
:
Pssm-ID: 408579 Cd Length: 90 Bit Score: 116.02 E-value: 1.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 264 DTNLTNMQRQLALEVIVTLSETAAAMLRKHTNIVAQSVPQMLTMMVDLEEDEEWAMADELEDDDFDSNAVAGESALDRIA 343
Cdd:pfam18808 1 NKDLDDAARQVALELLVTLAEAAPGMCRKQPQFTNALVPICLSMMTEVDDAEDWYTSDDLDDDDNEDNYVFGEQALDRLA 80
|
90
....*....|
gi 224496028 344 CGLGGKIILP 353
Cdd:pfam18808 81 CRLGGKALLP 90
|
|
| KAP95 super family |
cl27231 |
Karyopherin (importin) beta [Intracellular trafficking and secretion]; |
9-630 |
1.71e-12 |
|
Karyopherin (importin) beta [Intracellular trafficking and secretion];
The actual alignment was detected with superfamily member COG5215:
Pssm-ID: 227540 [Multi-domain] Cd Length: 858 Bit Score: 71.89 E-value: 1.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 9 LLLSNLMSPDNTVRKQSEEAYDTIPG---QTKITFLLQAIRDASAAEEVKQMAAVLLRRLLSSS-------FEEVYPNLT 78
Cdd:COG5215 9 LGKNHVLSPDPNARLRAEAQLLELQSgdfEQFISLLVQVLCDLNSNDQLRMVAGLILKNSLHANdpelqkgCSQRWLGMR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 79 VDIQTAIKTELLAGIRSeastnIRKKTCDIAAELARNLIDDD-GNNQWPEILKFLFDSV-NSQDVGLREAALHIFWNF-- 154
Cdd:COG5215 89 HESKEQVKGMALRALKS-----PEPRFCTMAAQLLAAIARMElPNSLWPGLMEEMVRNVgDEQPVSGKCESLGICGYHce 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 155 ---PGIFGNQQQhymeVIKRMLVQCMQDQENPQIRTLSARAA-------ASFILSNEGNTALlkhfsdllpgILQAVNES 224
Cdd:COG5215 164 seaPEDLIQMSN----VILFAIVMGALKNETTSAVRLAALKAlmdslmfVQGNFCYEEERNY----------FMQVVCEA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 225 CYRGDDSVLKS----LVEIA----DTAPKYLRPNLEATLQLSLK----------------LCADTNLTNMQRQLALEVIV 280
Cdd:COG5215 230 TQGNDEELQHAafgcLNKIMmlyyKFMQSYMENALAALTGRFMKsqndevaiqavefwstICEEEIDGEMEDKYLPEVPA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 281 TLSETAAAMlrkhtniVAQSVPQMLTMMVDLEEDEEwamadeleDDDFDSNAVAGeSALDRIACGLGGKIILPMIkQHIM 360
Cdd:COG5215 310 QNHGFARAA-------VADVLPELLSLLEKQGEDYY--------GDDWNPSMAAS-SCLQLFAQLKGDKIMRPVL-GFVE 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 361 QMLQNPDWKYRHAGLMALSAIGEG-CHQQMEAILSEIVSFVLLFCQDPHPRVRYAACNAIGQMATDFAPTFQKKFH-DKV 438
Cdd:COG5215 373 QNIRSESWANREAAVMAFGSVMHGpCEDCLTKIVPQALPGIENEMSDSCLWVKSTTAWCFGAIADHVAMIISPCGHlVLE 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 439 ISALLQTMEDqsNPRVQAHAAAALINFTEDCPK------TLLVPY----LDSLVQ---------HLHVIMVAKLQELIQK 499
Cdd:COG5215 453 VSASLIGLMD--CPFRSINCSWRKENLVDHIAKavreveSFLAKFylaiLNALVKgtelalnesNLRVSLFSALGTLILI 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 500 GTKLVLEqvvtSIASVADTAEEKFvpyyDLFMPSLKHIVENAIQKELRLLRGKTIECISLIgLAVGKEKFMPDASAVMQL 579
Cdd:COG5215 531 CPDAVSD----ILAGFYDYTSKKL----DECISVLGQILATEDQLLVEELQSNYIGVLEAI-IRTRRRDIEDVEDQLMEL 601
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 224496028 580 LLKT--QTDFNDLEDDdpqISYMISAwarMCKILGKEFQQYLPVVMgPLMKTA 630
Cdd:COG5215 602 FIRIleSTKPTTAFGD---VYTAISA---LSTSLEERFEQYASKFI-PYLTRA 647
|
|
| Importin_rep_5 super family |
cl40106 |
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
1001-1050 |
6.80e-06 |
|
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit and includes sequences not captured by pfam18808.
The actual alignment was detected with superfamily member pfam18816:
Pssm-ID: 465877 Cd Length: 52 Bit Score: 44.01 E-value: 6.80e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 224496028 1001 DKEEAVHTFNYLCDLIESNNPIVLGpdntNLPKIFAIIADGVANESVKGE 1050
Cdd:pfam18816 1 DEEAAPFAYRFLAELIEQNHPAVTS----QIPKVVDSVVQALEHKSLSGK 46
|
|
| HEAT_EZ |
pfam13513 |
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
915-962 |
2.90e-03 |
|
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
:
Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 36.96 E-value: 2.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 224496028 915 PEVRQAAAYGVGVMAQFGGENYRPAFTEAVPLLVGVIQSADSRAKENV 962
Cdd:pfam13513 1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAA 48
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Importin_rep_6 |
pfam18829 |
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
761-870 |
3.30e-42 |
|
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry represents two consecutive repeat units and includes sequences captured by pfam18808.
Pssm-ID: 465881 Cd Length: 110 Bit Score: 149.56 E-value: 3.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 761 VLSEIMHSFAKCIELMGDGCLNNEHFEELGGILKAKLEEHFKNQEVRQAKRQDEDYDEQVEETLQDEDENDVYILTKVSD 840
Cdd:pfam18829 1 VLAEYYSSLAECIEVLGPNCLSDEQMEEFIKAINSNLTEYFERVKEREEERKDDDYDEEVEEDLEEEEETDEELLSEINK 80
|
90 100 110
....*....|....*....|....*....|
gi 224496028 841 ILHSIFSSYREKVLPWFEQLLQLIVNLICP 870
Cdd:pfam18829 81 AIHAIFKTHKTAFLPYFEQLLPTVVAFLND 110
|
|
| Importin_rep_4 |
pfam18808 |
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
264-353 |
1.19e-30 |
|
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit.
Pssm-ID: 408579 Cd Length: 90 Bit Score: 116.02 E-value: 1.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 264 DTNLTNMQRQLALEVIVTLSETAAAMLRKHTNIVAQSVPQMLTMMVDLEEDEEWAMADELEDDDFDSNAVAGESALDRIA 343
Cdd:pfam18808 1 NKDLDDAARQVALELLVTLAEAAPGMCRKQPQFTNALVPICLSMMTEVDDAEDWYTSDDLDDDDNEDNYVFGEQALDRLA 80
|
90
....*....|
gi 224496028 344 CGLGGKIILP 353
Cdd:pfam18808 81 CRLGGKALLP 90
|
|
| KAP95 |
COG5215 |
Karyopherin (importin) beta [Intracellular trafficking and secretion]; |
9-630 |
1.71e-12 |
|
Karyopherin (importin) beta [Intracellular trafficking and secretion];
Pssm-ID: 227540 [Multi-domain] Cd Length: 858 Bit Score: 71.89 E-value: 1.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 9 LLLSNLMSPDNTVRKQSEEAYDTIPG---QTKITFLLQAIRDASAAEEVKQMAAVLLRRLLSSS-------FEEVYPNLT 78
Cdd:COG5215 9 LGKNHVLSPDPNARLRAEAQLLELQSgdfEQFISLLVQVLCDLNSNDQLRMVAGLILKNSLHANdpelqkgCSQRWLGMR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 79 VDIQTAIKTELLAGIRSeastnIRKKTCDIAAELARNLIDDD-GNNQWPEILKFLFDSV-NSQDVGLREAALHIFWNF-- 154
Cdd:COG5215 89 HESKEQVKGMALRALKS-----PEPRFCTMAAQLLAAIARMElPNSLWPGLMEEMVRNVgDEQPVSGKCESLGICGYHce 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 155 ---PGIFGNQQQhymeVIKRMLVQCMQDQENPQIRTLSARAA-------ASFILSNEGNTALlkhfsdllpgILQAVNES 224
Cdd:COG5215 164 seaPEDLIQMSN----VILFAIVMGALKNETTSAVRLAALKAlmdslmfVQGNFCYEEERNY----------FMQVVCEA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 225 CYRGDDSVLKS----LVEIA----DTAPKYLRPNLEATLQLSLK----------------LCADTNLTNMQRQLALEVIV 280
Cdd:COG5215 230 TQGNDEELQHAafgcLNKIMmlyyKFMQSYMENALAALTGRFMKsqndevaiqavefwstICEEEIDGEMEDKYLPEVPA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 281 TLSETAAAMlrkhtniVAQSVPQMLTMMVDLEEDEEwamadeleDDDFDSNAVAGeSALDRIACGLGGKIILPMIkQHIM 360
Cdd:COG5215 310 QNHGFARAA-------VADVLPELLSLLEKQGEDYY--------GDDWNPSMAAS-SCLQLFAQLKGDKIMRPVL-GFVE 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 361 QMLQNPDWKYRHAGLMALSAIGEG-CHQQMEAILSEIVSFVLLFCQDPHPRVRYAACNAIGQMATDFAPTFQKKFH-DKV 438
Cdd:COG5215 373 QNIRSESWANREAAVMAFGSVMHGpCEDCLTKIVPQALPGIENEMSDSCLWVKSTTAWCFGAIADHVAMIISPCGHlVLE 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 439 ISALLQTMEDqsNPRVQAHAAAALINFTEDCPK------TLLVPY----LDSLVQ---------HLHVIMVAKLQELIQK 499
Cdd:COG5215 453 VSASLIGLMD--CPFRSINCSWRKENLVDHIAKavreveSFLAKFylaiLNALVKgtelalnesNLRVSLFSALGTLILI 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 500 GTKLVLEqvvtSIASVADTAEEKFvpyyDLFMPSLKHIVENAIQKELRLLRGKTIECISLIgLAVGKEKFMPDASAVMQL 579
Cdd:COG5215 531 CPDAVSD----ILAGFYDYTSKKL----DECISVLGQILATEDQLLVEELQSNYIGVLEAI-IRTRRRDIEDVEDQLMEL 601
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 224496028 580 LLKT--QTDFNDLEDDdpqISYMISAwarMCKILGKEFQQYLPVVMgPLMKTA 630
Cdd:COG5215 602 FIRIleSTKPTTAFGD---VYTAISA---LSTSLEERFEQYASKFI-PYLTRA 647
|
|
| HEAT_EZ |
pfam13513 |
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
368-422 |
5.77e-09 |
|
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 53.14 E-value: 5.77e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 224496028 368 WKYRHAGLMALSAIGEGCHQQMEAILSEIVSFVLLFCQDPHPRVRYAACNAIGQM 422
Cdd:pfam13513 1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
|
|
| Importin_rep_5 |
pfam18816 |
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
1001-1050 |
6.80e-06 |
|
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit and includes sequences not captured by pfam18808.
Pssm-ID: 465877 Cd Length: 52 Bit Score: 44.01 E-value: 6.80e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 224496028 1001 DKEEAVHTFNYLCDLIESNNPIVLGpdntNLPKIFAIIADGVANESVKGE 1050
Cdd:pfam18816 1 DEEAAPFAYRFLAELIEQNHPAVTS----QIPKVVDSVVQALEHKSLSGK 46
|
|
| HEAT_EZ |
pfam13513 |
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
915-962 |
2.90e-03 |
|
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 36.96 E-value: 2.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 224496028 915 PEVRQAAAYGVGVMAQFGGENYRPAFTEAVPLLVGVIQSADSRAKENV 962
Cdd:pfam13513 1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAA 48
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Importin_rep_6 |
pfam18829 |
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
761-870 |
3.30e-42 |
|
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry represents two consecutive repeat units and includes sequences captured by pfam18808.
Pssm-ID: 465881 Cd Length: 110 Bit Score: 149.56 E-value: 3.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 761 VLSEIMHSFAKCIELMGDGCLNNEHFEELGGILKAKLEEHFKNQEVRQAKRQDEDYDEQVEETLQDEDENDVYILTKVSD 840
Cdd:pfam18829 1 VLAEYYSSLAECIEVLGPNCLSDEQMEEFIKAINSNLTEYFERVKEREEERKDDDYDEEVEEDLEEEEETDEELLSEINK 80
|
90 100 110
....*....|....*....|....*....|
gi 224496028 841 ILHSIFSSYREKVLPWFEQLLQLIVNLICP 870
Cdd:pfam18829 81 AIHAIFKTHKTAFLPYFEQLLPTVVAFLND 110
|
|
| Importin_rep_4 |
pfam18808 |
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
264-353 |
1.19e-30 |
|
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit.
Pssm-ID: 408579 Cd Length: 90 Bit Score: 116.02 E-value: 1.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 264 DTNLTNMQRQLALEVIVTLSETAAAMLRKHTNIVAQSVPQMLTMMVDLEEDEEWAMADELEDDDFDSNAVAGESALDRIA 343
Cdd:pfam18808 1 NKDLDDAARQVALELLVTLAEAAPGMCRKQPQFTNALVPICLSMMTEVDDAEDWYTSDDLDDDDNEDNYVFGEQALDRLA 80
|
90
....*....|
gi 224496028 344 CGLGGKIILP 353
Cdd:pfam18808 81 CRLGGKALLP 90
|
|
| KAP95 |
COG5215 |
Karyopherin (importin) beta [Intracellular trafficking and secretion]; |
9-630 |
1.71e-12 |
|
Karyopherin (importin) beta [Intracellular trafficking and secretion];
Pssm-ID: 227540 [Multi-domain] Cd Length: 858 Bit Score: 71.89 E-value: 1.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 9 LLLSNLMSPDNTVRKQSEEAYDTIPG---QTKITFLLQAIRDASAAEEVKQMAAVLLRRLLSSS-------FEEVYPNLT 78
Cdd:COG5215 9 LGKNHVLSPDPNARLRAEAQLLELQSgdfEQFISLLVQVLCDLNSNDQLRMVAGLILKNSLHANdpelqkgCSQRWLGMR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 79 VDIQTAIKTELLAGIRSeastnIRKKTCDIAAELARNLIDDD-GNNQWPEILKFLFDSV-NSQDVGLREAALHIFWNF-- 154
Cdd:COG5215 89 HESKEQVKGMALRALKS-----PEPRFCTMAAQLLAAIARMElPNSLWPGLMEEMVRNVgDEQPVSGKCESLGICGYHce 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 155 ---PGIFGNQQQhymeVIKRMLVQCMQDQENPQIRTLSARAA-------ASFILSNEGNTALlkhfsdllpgILQAVNES 224
Cdd:COG5215 164 seaPEDLIQMSN----VILFAIVMGALKNETTSAVRLAALKAlmdslmfVQGNFCYEEERNY----------FMQVVCEA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 225 CYRGDDSVLKS----LVEIA----DTAPKYLRPNLEATLQLSLK----------------LCADTNLTNMQRQLALEVIV 280
Cdd:COG5215 230 TQGNDEELQHAafgcLNKIMmlyyKFMQSYMENALAALTGRFMKsqndevaiqavefwstICEEEIDGEMEDKYLPEVPA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 281 TLSETAAAMlrkhtniVAQSVPQMLTMMVDLEEDEEwamadeleDDDFDSNAVAGeSALDRIACGLGGKIILPMIkQHIM 360
Cdd:COG5215 310 QNHGFARAA-------VADVLPELLSLLEKQGEDYY--------GDDWNPSMAAS-SCLQLFAQLKGDKIMRPVL-GFVE 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 361 QMLQNPDWKYRHAGLMALSAIGEG-CHQQMEAILSEIVSFVLLFCQDPHPRVRYAACNAIGQMATDFAPTFQKKFH-DKV 438
Cdd:COG5215 373 QNIRSESWANREAAVMAFGSVMHGpCEDCLTKIVPQALPGIENEMSDSCLWVKSTTAWCFGAIADHVAMIISPCGHlVLE 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 439 ISALLQTMEDqsNPRVQAHAAAALINFTEDCPK------TLLVPY----LDSLVQ---------HLHVIMVAKLQELIQK 499
Cdd:COG5215 453 VSASLIGLMD--CPFRSINCSWRKENLVDHIAKavreveSFLAKFylaiLNALVKgtelalnesNLRVSLFSALGTLILI 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 500 GTKLVLEqvvtSIASVADTAEEKFvpyyDLFMPSLKHIVENAIQKELRLLRGKTIECISLIgLAVGKEKFMPDASAVMQL 579
Cdd:COG5215 531 CPDAVSD----ILAGFYDYTSKKL----DECISVLGQILATEDQLLVEELQSNYIGVLEAI-IRTRRRDIEDVEDQLMEL 601
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 224496028 580 LLKT--QTDFNDLEDDdpqISYMISAwarMCKILGKEFQQYLPVVMgPLMKTA 630
Cdd:COG5215 602 FIRIleSTKPTTAFGD---VYTAISA---LSTSLEERFEQYASKFI-PYLTRA 647
|
|
| HEAT_EZ |
pfam13513 |
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
368-422 |
5.77e-09 |
|
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 53.14 E-value: 5.77e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 224496028 368 WKYRHAGLMALSAIGEGCHQQMEAILSEIVSFVLLFCQDPHPRVRYAACNAIGQM 422
Cdd:pfam13513 1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
|
|
| HEAT_2 |
pfam13646 |
HEAT repeats; This family includes multiple HEAT repeats. |
361-462 |
7.21e-08 |
|
HEAT repeats; This family includes multiple HEAT repeats.
Pssm-ID: 433376 [Multi-domain] Cd Length: 88 Bit Score: 50.80 E-value: 7.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 361 QMLQNPDWKYRHAGLMALSAIGEgchqqmeailSEIVSFVLLFCQDPHPRVRYAACNAIGQMATdfaptfqkkfhDKVIS 440
Cdd:pfam13646 7 ALLRDPDPEVRAAAIRALGRIGD----------PEAVPALLELLKDEDPAVRRAAAEALGKIGD-----------PEALP 65
|
90 100
....*....|....*....|..
gi 224496028 441 ALLQTMEDQSNPRVQAHAAAAL 462
Cdd:pfam13646 66 ALLELLRDDDDDVVRAAAAEAL 87
|
|
| HEAT |
COG1413 |
HEAT repeat [General function prediction only]; |
357-479 |
9.31e-08 |
|
HEAT repeat [General function prediction only];
Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 51.94 E-value: 9.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 357 QHIMQMLQNPDWKYRHAGLMALSAIGEgchqqmeailSEIVSFVLLFCQDPHPRVRYAACNAIGQMATdfaptfqkkfhD 436
Cdd:COG1413 19 PALIAALADEDPDVRAAAARALGRLGD----------PRAVPALLEALKDPDPEVRAAAAEALGRIGD-----------P 77
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 224496028 437 KVISALLQTMEDqSNPRVQAHAAAALINFTEDCPKTLLVPYLD 479
Cdd:COG1413 78 EAVPALIAALKD-EDPEVRRAAAEALGRLGDPAAVPALLEALK 119
|
|
| HEAT |
COG1413 |
HEAT repeat [General function prediction only]; |
348-462 |
2.66e-07 |
|
HEAT repeat [General function prediction only];
Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 50.78 E-value: 2.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 224496028 348 GKIILPMIKQHIMQMLQNPDWKYRHAGLMALSAIGEgchqqmeailSEIVSFVLLFCQDPHPRVRYAACNAIGQMATDFA 427
Cdd:COG1413 41 GRLGDPRAVPALLEALKDPDPEVRAAAAEALGRIGD----------PEAVPALIAALKDEDPEVRRAAAEALGRLGDPAA 110
|
90 100 110
....*....|....*....|....*....|....*
gi 224496028 428 ptfqkkfhdkvISALLQTMEDQsNPRVQAHAAAAL 462
Cdd:COG1413 111 -----------VPALLEALKDP-DWEVRRAAARAL 133
|
|
| Importin_rep_5 |
pfam18816 |
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ... |
1001-1050 |
6.80e-06 |
|
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit and includes sequences not captured by pfam18808.
Pssm-ID: 465877 Cd Length: 52 Bit Score: 44.01 E-value: 6.80e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 224496028 1001 DKEEAVHTFNYLCDLIESNNPIVLGpdntNLPKIFAIIADGVANESVKGE 1050
Cdd:pfam18816 1 DEEAAPFAYRFLAELIEQNHPAVTS----QIPKVVDSVVQALEHKSLSGK 46
|
|
| Vac14_Fab1_bd |
pfam12755 |
Vacuolar 14 Fab1-binding region; Vac14 is a scaffold for the Fab1 kinase complex, a complex ... |
370-418 |
3.13e-05 |
|
Vacuolar 14 Fab1-binding region; Vac14 is a scaffold for the Fab1 kinase complex, a complex that allows for the dynamic interconversion of PI3P and PI(3,5)P2p (phosphoinositide phosphate (PIP) lipids, that are generated transiently on the cytoplasmic face of selected intracellular membranes). This interconversion is regulated by at least five proteins in yeast: the lipid kinase Fab1p, lipid phosphatase Fig4p, the Fab1p activator Vac7p, the Fab1p inhibitor Atg18p, and Vac14p, a protein required for the activity of both Fab1p and Fig4p. This domain appears to be the one responsible for binding to Fab1. The full length Vac14 in yeasts is likely to be a protein carrying a succession of HEAT repeats, most of which have now degenerated. This regulatory system is crucial for the proper functioning of the mammalian nervous system.
Pssm-ID: 403838 Cd Length: 97 Bit Score: 43.74 E-value: 3.13e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 224496028 370 YRHAGLMALSAIGEGCHQQMEAILSEIVSFVLLFCQDPHPRVRYAACNA 418
Cdd:pfam12755 2 ARKGGLIGLAATAIALGKDIAPYLDDIIPPVLACFSDQDSRVRYYACES 50
|
|
| HEAT_EZ |
pfam13513 |
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
409-465 |
4.98e-05 |
|
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 41.97 E-value: 4.98e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 224496028 409 PRVRYAACNAIGQMAtDFAPTFQKKFHDKVISALLQTMEDqSNPRVQAHAAAALINF 465
Cdd:pfam13513 1 WRVREAAALALGSLA-EGGPDLLAPAVPELLPALLPLLND-DSDLVREAAAWALGRL 55
|
|
| HEAT |
pfam02985 |
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see ... |
396-423 |
6.60e-04 |
|
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514).
Pssm-ID: 460773 Cd Length: 31 Bit Score: 37.89 E-value: 6.60e-04
10 20
....*....|....*....|....*...
gi 224496028 396 IVSFVLLFCQDPHPRVRYAACNAIGQMA 423
Cdd:pfam02985 1 LLPLLLKLLNDPSPEVREAAAEALGELA 28
|
|
| HEAT |
COG1413 |
HEAT repeat [General function prediction only]; |
348-423 |
2.41e-03 |
|
HEAT repeat [General function prediction only];
Pssm-ID: 441023 [Multi-domain] Cd Length: 137 Bit Score: 39.23 E-value: 2.41e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 224496028 348 GKIILPMIKQHIMQMLQNPDWKYRHAGLMALSAIGEgchqqmeailSEIVSFVLLFCQDPHPRVRYAACNAIGQMA 423
Cdd:COG1413 72 GRIGDPEAVPALIAALKDEDPEVRRAAAEALGRLGD----------PAAVPALLEALKDPDWEVRRAAARALGRLG 137
|
|
| HEAT_EZ |
pfam13513 |
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ... |
915-962 |
2.90e-03 |
|
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.
Pssm-ID: 463906 [Multi-domain] Cd Length: 55 Bit Score: 36.96 E-value: 2.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 224496028 915 PEVRQAAAYGVGVMAQFGGENYRPAFTEAVPLLVGVIQSADSRAKENV 962
Cdd:pfam13513 1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAA 48
|
|
| IBN_N |
pfam03810 |
Importin-beta N-terminal domain; |
40-95 |
5.75e-03 |
|
Importin-beta N-terminal domain;
Pssm-ID: 397745 [Multi-domain] Cd Length: 72 Bit Score: 36.45 E-value: 5.75e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 224496028 40 FLLQAIRDASAAEEVKQMAAVLLRRLLSSSFEEVYPNLTVDIQTAIKTELLAGIRS 95
Cdd:pfam03810 17 KLLQILSNSENPLEVRQLAALYLKNLITRHWEEEKNSLPPEEKEQIKNNLLNLLGS 72
|
|
| HEAT |
pfam02985 |
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see ... |
902-931 |
7.94e-03 |
|
HEAT repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514).
Pssm-ID: 460773 Cd Length: 31 Bit Score: 34.81 E-value: 7.94e-03
10 20 30
....*....|....*....|....*....|
gi 224496028 902 FLRPMMQSLCDTSPEVRQAAAYGVGVMAQF 931
Cdd:pfam02985 1 LLPLLLKLLNDPSPEVREAAAEALGELAEV 30
|
|
| |
