|
Name |
Accession |
Description |
Interval |
E-value |
| UDPGT |
pfam00201 |
UDP-glucoronosyl and UDP-glucosyl transferase; |
21-519 |
0e+00 |
|
UDP-glucoronosyl and UDP-glucosyl transferase;
Pssm-ID: 278624 [Multi-domain] Cd Length: 499 Bit Score: 614.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 21 GRVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEVVDYLWIHF-HELWMNETI 99
Cdd:pfam00201 1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGKPSNLKFETYPTSATKEELENPFPKRqMQWFEEASF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 100 STYEKTLEVWQLMS-LFRAHSEELVkglFDVGLLKTLRDSNYDVLFSDLTMPFSDLMAQKLNIPHVLSMRISFASALERL 178
Cdd:pfam00201 81 GTVWSYFSALQEYSdGYRVTCKELV---GNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 179 CGQMPVPQSYVPAAVAQghLTDRMSFTERVENMLLYITHTAMFQLTTKfTFDHIYAEISGEPTTMCETIGKTDIWLIRTY 258
Cdd:pfam00201 158 SGGLPSPPSYVPVILSD--LSDHMTFMERVKNMLIMLYFDFWFQCFPR-KWDQFASEVLGRPVTLPELMSKASVWLIRSY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 259 WDFEYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVFSLGSMIKNLTVQKANTIAAALGQISQKVVWRYSG 338
Cdd:pfam00201 235 WDLEFPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 339 KTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLE 418
Cdd:pfam00201 315 TKPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 419 SKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIT 498
Cdd:pfam00201 395 SEDLLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACV 474
|
490 500
....*....|....*....|.
gi 221307477 499 ALITFLWVKACCFLFRRCVRK 519
Cdd:pfam00201 475 ATVAFITFKCCLFGYRKFVGK 495
|
|
| GT1_Gtf-like |
cd03784 |
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ... |
22-460 |
2.12e-71 |
|
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
Pssm-ID: 340817 [Multi-domain] Cd Length: 404 Bit Score: 233.60 E-value: 2.12e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 22 RVLVMP-GEYSHWHNMRPVIEALVDKNHSVTVLvgsssptvphTQKERFEYHVFKVNMEkeVVDYLWIHFHELWMNETIS 100
Cdd:cd03784 2 RILFVPfPGQGHVNPMLPLAKALAARGHEVTVA----------TPPFNFADLVEAAGLT--FVPVGDDPDELELDSETNL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 101 TYEktlEVWQLMSLFRAHSEELVKGLFDvgllKTLRDSNYDVLFSDLTMPFSDLMAQKLNIPHVL---SMRISFASALER 177
Cdd:cd03784 70 GPD---SLLELLRRLLKAADELLDDLLA----ALRSSWKPDLVIADPFAYAGPLVAEELGIPSVRlftGPATLLSAYLHP 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 178 LCGQMPVPQSYVPAAVAQGHLTDRMSFTERVenmllYITHTAMFQLTTKFTFDHIYaeisgepttmceTIGKTDIWLirt 257
Cdd:cd03784 143 FGVLNLLLSSLLEPELFLDPLLEVLDRLRER-----LGLPPFSLVLLLLRLVPPLY------------VIGPTFPSL--- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 258 ywdfeYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVFSLGSMIKNLTVQKANTIAAALGQISQKVVWRY- 336
Cdd:cd03784 203 -----PPDRPRLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVg 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 337 --SGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDF 414
Cdd:cd03784 278 pdPLGGLERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDK 357
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 221307477 415 FTLESKDLVDALKTVLNNPSYKESIMRLSRIH-HDQPMKPLDQAVYW 460
Cdd:cd03784 358 DELTAEELAKAVREVLEDESYRRAAELLAELReEDGAPSAADVVERL 404
|
|
| egt |
PHA03392 |
ecdysteroid UDP-glucosyltransferase; Provisional |
254-485 |
1.03e-42 |
|
ecdysteroid UDP-glucosyltransferase; Provisional
Pssm-ID: 223071 [Multi-domain] Cd Length: 507 Bit Score: 159.35 E-value: 1.03e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 254 LIRTYWDFEYPRPFPPNFKFVGG--LQCKPAKPLAKELEEFVQSSGDhGIVVFSLGSMIKnltvqkANTIAA-------- 323
Cdd:PHA03392 250 FVNVHPVFDNNRPVPPSVQYLGGlhLHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSID------TNDMDNeflqmllr 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 324 ALGQISQKVVWRYSGKTPE-TLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMH 402
Cdd:PHA03392 323 TFKKLPYNVLWKYDGEVEAiNLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNK 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 403 LKSKGAAVVLDFFTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKG-AKHLRVQAHELS 481
Cdd:PHA03392 403 YVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVS 482
|
....
gi 221307477 482 WYQY 485
Cdd:PHA03392 483 YSDY 486
|
|
| YjiC |
COG1819 |
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]; |
261-444 |
1.30e-37 |
|
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
Pssm-ID: 441424 [Multi-domain] Cd Length: 268 Bit Score: 139.22 E-value: 1.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 261 FEYPRP-FPPNFKFVGGLQCKPAKplakELEEFVQSSGDHGIVVFSLGSMIkNLTVQKANTIAAALGQISQKVVWRYSGK 339
Cdd:COG1819 85 LEYPRPpDPANVRFVGPLLPDGPA----ELPPWLEEDAGRPLVYVTLGTSA-NDRADLLRAVLEALADLGVRVVVTTGGL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 340 TPETLAP---NTKIYDWIPQNDLLghPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFT 416
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALL--PRADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237
|
170 180
....*....|....*....|....*...
gi 221307477 417 LESKDLVDALKTVLNNPSYKESIMRLSR 444
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLAA 265
|
|
| MGT |
TIGR01426 |
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ... |
264-444 |
4.37e-21 |
|
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
Pssm-ID: 273616 [Multi-domain] Cd Length: 392 Bit Score: 95.14 E-value: 4.37e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 264 PRPFPPN-------FKFVGglqckPAKPLAKELEEFVQSSGDHGIVVFSLGSmIKNLTVQKANTIAAALGQISQKVVWRY 336
Cdd:TIGR01426 188 PKAFQPAgetfddsFTFVG-----PCIGDRKEDGSWERPGDGRPVVLISLGT-VFNNQPSFYRTCVEAFRDLDWHVVLSV 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 337 SGKT-PETLA---PNTKIYDWIPQNDLLghPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVL 412
Cdd:TIGR01426 262 GRGVdPADLGelpPNVEVRQWVPQLEIL--KKADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHL 339
|
170 180 190
....*....|....*....|....*....|..
gi 221307477 413 DFFTLESKDLVDALKTVLNNPSYKESIMRLSR 444
Cdd:TIGR01426 340 PPEEVTAEKLREAVLAVLSDPRYAERLRKMRA 371
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| UDPGT |
pfam00201 |
UDP-glucoronosyl and UDP-glucosyl transferase; |
21-519 |
0e+00 |
|
UDP-glucoronosyl and UDP-glucosyl transferase;
Pssm-ID: 278624 [Multi-domain] Cd Length: 499 Bit Score: 614.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 21 GRVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEVVDYLWIHF-HELWMNETI 99
Cdd:pfam00201 1 GKVLVWPMDGSHWMNMKGILEELVQRGHEVTVLRPSASISIGPGKPSNLKFETYPTSATKEELENPFPKRqMQWFEEASF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 100 STYEKTLEVWQLMS-LFRAHSEELVkglFDVGLLKTLRDSNYDVLFSDLTMPFSDLMAQKLNIPHVLSMRISFASALERL 178
Cdd:pfam00201 81 GTVWSYFSALQEYSdGYRVTCKELV---GNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEKV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 179 CGQMPVPQSYVPAAVAQghLTDRMSFTERVENMLLYITHTAMFQLTTKfTFDHIYAEISGEPTTMCETIGKTDIWLIRTY 258
Cdd:pfam00201 158 SGGLPSPPSYVPVILSD--LSDHMTFMERVKNMLIMLYFDFWFQCFPR-KWDQFASEVLGRPVTLPELMSKASVWLIRSY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 259 WDFEYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVFSLGSMIKNLTVQKANTIAAALGQISQKVVWRYSG 338
Cdd:pfam00201 235 WDLEFPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMVSNIPEEKANAIASALAQIPQKVLWRFDG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 339 KTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFTLE 418
Cdd:pfam00201 315 TKPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTLNVLTMT 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 419 SKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIT 498
Cdd:pfam00201 395 SEDLLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIGFLLACV 474
|
490 500
....*....|....*....|.
gi 221307477 499 ALITFLWVKACCFLFRRCVRK 519
Cdd:pfam00201 475 ATVAFITFKCCLFGYRKFVGK 495
|
|
| GT1_Gtf-like |
cd03784 |
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ... |
22-460 |
2.12e-71 |
|
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
Pssm-ID: 340817 [Multi-domain] Cd Length: 404 Bit Score: 233.60 E-value: 2.12e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 22 RVLVMP-GEYSHWHNMRPVIEALVDKNHSVTVLvgsssptvphTQKERFEYHVFKVNMEkeVVDYLWIHFHELWMNETIS 100
Cdd:cd03784 2 RILFVPfPGQGHVNPMLPLAKALAARGHEVTVA----------TPPFNFADLVEAAGLT--FVPVGDDPDELELDSETNL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 101 TYEktlEVWQLMSLFRAHSEELVKGLFDvgllKTLRDSNYDVLFSDLTMPFSDLMAQKLNIPHVL---SMRISFASALER 177
Cdd:cd03784 70 GPD---SLLELLRRLLKAADELLDDLLA----ALRSSWKPDLVIADPFAYAGPLVAEELGIPSVRlftGPATLLSAYLHP 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 178 LCGQMPVPQSYVPAAVAQGHLTDRMSFTERVenmllYITHTAMFQLTTKFTFDHIYaeisgepttmceTIGKTDIWLirt 257
Cdd:cd03784 143 FGVLNLLLSSLLEPELFLDPLLEVLDRLRER-----LGLPPFSLVLLLLRLVPPLY------------VIGPTFPSL--- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 258 ywdfeYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVFSLGSMIKNLTVQKANTIAAALGQISQKVVWRY- 336
Cdd:cd03784 203 -----PPDRPRLPSVLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVRDLPEELLELIAEALASLGQRFLWVVg 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 337 --SGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDF 414
Cdd:cd03784 278 pdPLGGLERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDK 357
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 221307477 415 FTLESKDLVDALKTVLNNPSYKESIMRLSRIH-HDQPMKPLDQAVYW 460
Cdd:cd03784 358 DELTAEELAKAVREVLEDESYRRAAELLAELReEDGAPSAADVVERL 404
|
|
| egt |
PHA03392 |
ecdysteroid UDP-glucosyltransferase; Provisional |
254-485 |
1.03e-42 |
|
ecdysteroid UDP-glucosyltransferase; Provisional
Pssm-ID: 223071 [Multi-domain] Cd Length: 507 Bit Score: 159.35 E-value: 1.03e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 254 LIRTYWDFEYPRPFPPNFKFVGG--LQCKPAKPLAKELEEFVQSSGDhGIVVFSLGSMIKnltvqkANTIAA-------- 323
Cdd:PHA03392 250 FVNVHPVFDNNRPVPPSVQYLGGlhLHKKPPQPLDDYLEEFLNNSTN-GVVYVSFGSSID------TNDMDNeflqmllr 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 324 ALGQISQKVVWRYSGKTPE-TLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMH 402
Cdd:PHA03392 323 TFKKLPYNVLWKYDGEVEAiNLPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNK 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 403 LKSKGAAVVLDFFTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKG-AKHLRVQAHELS 481
Cdd:PHA03392 403 YVELGIGRALDTVTVSAAQLVLAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIRNKHgNTSLKTKAANVS 482
|
....
gi 221307477 482 WYQY 485
Cdd:PHA03392 483 YSDY 486
|
|
| YjiC |
COG1819 |
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]; |
261-444 |
1.30e-37 |
|
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
Pssm-ID: 441424 [Multi-domain] Cd Length: 268 Bit Score: 139.22 E-value: 1.30e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 261 FEYPRP-FPPNFKFVGGLQCKPAKplakELEEFVQSSGDHGIVVFSLGSMIkNLTVQKANTIAAALGQISQKVVWRYSGK 339
Cdd:COG1819 85 LEYPRPpDPANVRFVGPLLPDGPA----ELPPWLEEDAGRPLVYVTLGTSA-NDRADLLRAVLEALADLGVRVVVTTGGL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 340 TPETLAP---NTKIYDWIPQNDLLghPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVLDFFT 416
Cdd:COG1819 160 DPAELGPlpdNVRVVDYVPQDALL--PRADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLALPPRR 237
|
170 180
....*....|....*....|....*...
gi 221307477 417 LESKDLVDALKTVLNNPSYKESIMRLSR 444
Cdd:COG1819 238 LTAEALRAALRRLLADPSYRERAARLAA 265
|
|
| MGT |
TIGR01426 |
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ... |
264-444 |
4.37e-21 |
|
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
Pssm-ID: 273616 [Multi-domain] Cd Length: 392 Bit Score: 95.14 E-value: 4.37e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 264 PRPFPPN-------FKFVGglqckPAKPLAKELEEFVQSSGDHGIVVFSLGSmIKNLTVQKANTIAAALGQISQKVVWRY 336
Cdd:TIGR01426 188 PKAFQPAgetfddsFTFVG-----PCIGDRKEDGSWERPGDGRPVVLISLGT-VFNNQPSFYRTCVEAFRDLDWHVVLSV 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 337 SGKT-PETLA---PNTKIYDWIPQNDLLghPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSKGAAVVL 412
Cdd:TIGR01426 262 GRGVdPADLGelpPNVEVRQWVPQLEIL--KKADAFITHGGMNSTMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHL 339
|
170 180 190
....*....|....*....|....*....|..
gi 221307477 413 DFFTLESKDLVDALKTVLNNPSYKESIMRLSR 444
Cdd:TIGR01426 340 PPEEVTAEKLREAVLAVLSDPRYAERLRKMRA 371
|
|
| PLN00164 |
PLN00164 |
glucosyltransferase; Provisional |
302-413 |
1.55e-11 |
|
glucosyltransferase; Provisional
Pssm-ID: 215084 [Multi-domain] Cd Length: 480 Bit Score: 66.62 E-value: 1.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 302 VVF-SLGSMiKNLTVQKANTIAAALGQISQKVVWRYSGKTP-----------ETLAPN-----TKIY-----DWIPQNDL 359
Cdd:PLN00164 274 VVFlCFGSM-GFFDAPQVREIAAGLERSGHRFLWVLRGPPAagsrhptdadlDELLPEgflerTKGRglvwpTWAPQKEI 352
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 221307477 360 LGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHL-KSKGAAVVLD 413
Cdd:PLN00164 353 LAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNAFELvADMGVAVAMK 407
|
|
| PLN02210 |
PLN02210 |
UDP-glucosyl transferase |
291-397 |
7.39e-10 |
|
UDP-glucosyl transferase
Pssm-ID: 215127 [Multi-domain] Cd Length: 456 Bit Score: 61.21 E-value: 7.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 291 EFVQSSGDHGIVVFSLGSMIKNLTVQkANTIAAALGQISQKVVW----RYSGKTPETLAPNTK-----IYDWIPQNDLLG 361
Cdd:PLN02210 261 EWLDKQARSSVVYISFGSMLESLENQ-VETIAKALKNRGVPFLWvirpKEKAQNVQVLQEMVKegqgvVLEWSPQEKILS 339
|
90 100 110
....*....|....*....|....*....|....*.
gi 221307477 362 HPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQP 397
Cdd:PLN02210 340 HMAISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQP 375
|
|
| PLN02555 |
PLN02555 |
limonoid glucosyltransferase |
265-403 |
1.64e-09 |
|
limonoid glucosyltransferase
Pssm-ID: 178170 [Multi-domain] Cd Length: 480 Bit Score: 60.20 E-value: 1.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 265 RPFPPNFKF-------VGGLQCKPAKPLAKELEEFVQSSgdhgIVVFSLGSMIkNLTVQKANTIAAALGQISQKVVW--- 334
Cdd:PLN02555 240 KPVGPLFKMaktpnsdVKGDISKPADDCIEWLDSKPPSS----VVYISFGTVV-YLKQEQIDEIAYGVLNSGVSFLWvmr 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 335 ---RYSGKTP--------ETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHL 403
Cdd:PLN02555 315 pphKDSGVEPhvlpeeflEKAGDKGKIVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYL 394
|
|
| PLN02992 |
PLN02992 |
coniferyl-alcohol glucosyltransferase |
244-413 |
5.91e-09 |
|
coniferyl-alcohol glucosyltransferase
Pssm-ID: 178572 [Multi-domain] Cd Length: 481 Bit Score: 58.45 E-value: 5.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 244 CETIGKTDIWLIRTYWDFEyPRPF-----PPNFKFVGGLQCKPAKPLAKELE---------EFVQSSGDHGIVVFSLGSM 309
Cdd:PLN02992 195 GLAYPKADGILVNTWEEME-PKSLkslqdPKLLGRVARVPVYPIGPLCRPIQssktdhpvlDWLNKQPNESVLYISFGSG 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 310 iKNLTVQKANTIAAALGQISQKVVW------------RY----SGKT--------PETLAPNTK-----IYDWIPQNDLL 360
Cdd:PLN02992 274 -GSLSAKQLTELAWGLEMSQQRFVWvvrppvdgsacsAYfsanGGETrdntpeylPEGFVSRTHdrgfvVPSWAPQAEIL 352
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 221307477 361 GHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSK-GAAVVLD 413
Cdd:PLN02992 353 AHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNAALLSDElGIAVRSD 406
|
|
| PLN02173 |
PLN02173 |
UDP-glucosyl transferase family protein |
301-404 |
8.83e-09 |
|
UDP-glucosyl transferase family protein
Pssm-ID: 177830 [Multi-domain] Cd Length: 449 Bit Score: 57.73 E-value: 8.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 301 IVVFSLGSMIKnLTVQKANTIAAALGQISQKVVWRYS--GKTP----ETLAPNTK-IYDWIPQNDLLGHPKTKAFITHGG 373
Cdd:PLN02173 266 VVYIAFGSMAK-LSSEQMEEIASAISNFSYLWVVRASeeSKLPpgflETVDKDKSlVLKWSPQLQVLSNKAIGCFMTHCG 344
|
90 100 110
....*....|....*....|....*....|.
gi 221307477 374 TNGLYEAIYHGVPMVGLPLFGDQPDNLMHLK 404
Cdd:PLN02173 345 WNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQ 375
|
|
| PLN02448 |
PLN02448 |
UDP-glycosyltransferase family protein |
305-399 |
1.20e-08 |
|
UDP-glycosyltransferase family protein
Pssm-ID: 215247 [Multi-domain] Cd Length: 459 Bit Score: 57.32 E-value: 1.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 305 SLGSMiknLTVQKANT--IAAALGQISQKVVWRYSGKTP---ETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYE 379
Cdd:PLN02448 280 SLGSF---LSVSSAQMdeIAAGLRDSGVRFLWVARGEASrlkEICGDMGLVVPWCDQLKVLCHSSVGGFWTHCGWNSTLE 356
|
90 100
....*....|....*....|
gi 221307477 380 AIYHGVPMVGLPLFGDQPDN 399
Cdd:PLN02448 357 AVFAGVPMLTFPLFWDQPLN 376
|
|
| PLN02207 |
PLN02207 |
UDP-glycosyltransferase |
278-445 |
2.29e-08 |
|
UDP-glycosyltransferase
Pssm-ID: 177857 [Multi-domain] Cd Length: 468 Bit Score: 56.58 E-value: 2.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 278 QCKPAKPLAK--ELEEFVQSSGDHGIVVFSLGSMiKNLTVQKANTIAAALGQISQKVVW--RYSGKTPETLAPNT----- 348
Cdd:PLN02207 252 QPHPEQDLARrdELMKWLDDQPEASVVFLCFGSM-GRLRGPLVKEIAHGLELCQYRFLWslRTEEVTNDDLLPEGfldrv 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 349 ----KIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDN-LMHLKSKGAAVVLDF-FTLESKDL 422
Cdd:PLN02207 331 sgrgMICGWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNaFLMVKELKLAVELKLdYRVHSDEI 410
|
170 180 190
....*....|....*....|....*....|.
gi 221307477 423 VD------ALKTVLN--NPSYKESIMRLSRI 445
Cdd:PLN02207 411 VNaneietAIRCVMNkdNNVVRKRVMDISQM 441
|
|
| PLN02554 |
PLN02554 |
UDP-glycosyltransferase family protein |
349-403 |
9.47e-08 |
|
UDP-glycosyltransferase family protein
Pssm-ID: 215304 Cd Length: 481 Bit Score: 54.41 E-value: 9.47e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 221307477 349 KIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHL 403
Cdd:PLN02554 345 KVIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNAFEM 399
|
|
| PLN02410 |
PLN02410 |
UDP-glucoronosyl/UDP-glucosyl transferase family protein |
291-404 |
1.66e-07 |
|
UDP-glucoronosyl/UDP-glucosyl transferase family protein
Pssm-ID: 178032 [Multi-domain] Cd Length: 451 Bit Score: 53.89 E-value: 1.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 291 EFVQSSGDHGIVVFSLGSmIKNLTVQKANTIAAALGQISQKVVW----------RYSGKTPETLAP----NTKIYDWIPQ 356
Cdd:PLN02410 256 EWLNKQKKNSVIFVSLGS-LALMEINEVMETASGLDSSNQQFLWvirpgsvrgsEWIESLPKEFSKiisgRGYIVKWAPQ 334
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 221307477 357 NDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLK 404
Cdd:PLN02410 335 KEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLE 382
|
|
| PLN02167 |
PLN02167 |
UDP-glycosyltransferase family protein |
261-410 |
2.99e-07 |
|
UDP-glycosyltransferase family protein
Pssm-ID: 215112 [Multi-domain] Cd Length: 475 Bit Score: 52.88 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 261 FEY----PRPFPPNFKfVGGLQCKPAKP-----------LAKELEEFVQSSgdhgIVVFSLGSMiKNLTVQKANTIAAAL 325
Cdd:PLN02167 232 FDYfsrlPENYPPVYP-VGPILSLKDRTspnldssdrdrIMRWLDDQPESS----VVFLCFGSL-GSLPAPQIKEIAQAL 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 326 GQISQKVVWRYSGKTPETLAPNTK--------------IYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLP 391
Cdd:PLN02167 306 ELVGCRFLWSIRTNPAEYASPYEPlpegfmdrvmgrglVCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWP 385
|
170 180
....*....|....*....|
gi 221307477 392 LFGDQPDNLMHL-KSKGAAV 410
Cdd:PLN02167 386 MYAEQQLNAFTMvKELGLAV 405
|
|
| PLN02534 |
PLN02534 |
UDP-glycosyltransferase |
350-396 |
1.27e-06 |
|
UDP-glycosyltransferase
Pssm-ID: 215293 [Multi-domain] Cd Length: 491 Bit Score: 51.01 E-value: 1.27e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 221307477 350 IYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQ 396
Cdd:PLN02534 348 IKGWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQ 394
|
|
| PLN03015 |
PLN03015 |
UDP-glucosyl transferase |
291-410 |
1.49e-06 |
|
UDP-glucosyl transferase
Pssm-ID: 178589 [Multi-domain] Cd Length: 470 Bit Score: 50.85 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 291 EFVQSSGDHGIVVFSLGSMiKNLTVQKANTIAAALGQISQKVVW-----------------RYSGKTPETLAPNTK---- 349
Cdd:PLN03015 259 EWLDKQGERSVVYVCLGSG-GTLTFEQTVELAWGLELSGQRFVWvlrrpasylgasssdddQVSASLPEGFLDRTRgvgl 337
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221307477 350 -IYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSK-GAAV 410
Cdd:PLN03015 338 vVTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNATLLTEEiGVAV 400
|
|
| PLN02863 |
PLN02863 |
UDP-glucoronosyl/UDP-glucosyl transferase family protein |
350-396 |
3.54e-06 |
|
UDP-glucoronosyl/UDP-glucosyl transferase family protein
Pssm-ID: 215465 Cd Length: 477 Bit Score: 49.48 E-value: 3.54e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 221307477 350 IYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQ 396
Cdd:PLN02863 347 IRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQ 393
|
|
| PLN02152 |
PLN02152 |
indole-3-acetate beta-glucosyltransferase |
292-399 |
4.59e-06 |
|
indole-3-acetate beta-glucosyltransferase
Pssm-ID: 177813 [Multi-domain] Cd Length: 455 Bit Score: 49.28 E-value: 4.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 292 FVQSSGDHGIVVFSLGSMIKnLTVQKANTIAAALGQISQKVVWRYSGKT---------PET-----------LAPNTKIY 351
Cdd:PLN02152 254 WLDSKTESSVIYVSFGTMVE-LSKKQIEELARALIEGKRPFLWVITDKLnreakiegeEETeiekiagfrheLEEVGMIV 332
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 221307477 352 DWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDN 399
Cdd:PLN02152 333 SWCSQIEVLRHRAVGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPAN 380
|
|
| PLN03007 |
PLN03007 |
UDP-glucosyltransferase family protein |
301-396 |
7.80e-06 |
|
UDP-glucosyltransferase family protein
Pssm-ID: 178584 [Multi-domain] Cd Length: 482 Bit Score: 48.32 E-value: 7.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 301 IVVFSLGSMiKNLTVQKANTIAAALGQISQKVVWRYSGKT---------PETLAPNTK-----IYDWIPQNDLLGHPKTK 366
Cdd:PLN03007 287 VIYLSFGSV-ASFKNEQLFEIAAGLEGSGQNFIWVVRKNEnqgekeewlPEGFEERTKgkgliIRGWAPQVLILDHQATG 365
|
90 100 110
....*....|....*....|....*....|
gi 221307477 367 AFITHGGTNGLYEAIYHGVPMVGLPLFGDQ 396
Cdd:PLN03007 366 GFVTHCGWNSLLEGVAAGLPMVTWPVGAEQ 395
|
|
| PLN03004 |
PLN03004 |
UDP-glycosyltransferase |
350-399 |
7.86e-06 |
|
UDP-glycosyltransferase
Pssm-ID: 178581 Cd Length: 451 Bit Score: 48.53 E-value: 7.86e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 221307477 350 IYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDN 399
Cdd:PLN03004 338 VKSWAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFN 387
|
|
| PLN02562 |
PLN02562 |
UDP-glycosyltransferase |
301-442 |
4.73e-05 |
|
UDP-glycosyltransferase
Pssm-ID: 215305 Cd Length: 448 Bit Score: 46.03 E-value: 4.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 301 IVVFSLGSMIKNLTVQKANTIAAALGQISQKVVWRYSGKTPETLAP--------NTKIYDWIPQNDLLGHPKTKAFITHG 372
Cdd:PLN02562 275 VIYISFGSWVSPIGESNVRTLALALEASGRPFIWVLNPVWREGLPPgyvervskQGKVVSWAPQLEVLKHQAVGCYLTHC 354
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 221307477 373 GTNGLYEAIYHGVPMVGLPLFGDQPDNLMHLKSK-GAAVVLDFFTleSKDLVDALKTVLNNPSYKESIMRL 442
Cdd:PLN02562 355 GWNSTMEAIQCQKRLLCYPVAGDQFVNCAYIVDVwKIGVRISGFG--QKEVEEGLRKVMEDSGMGERLMKL 423
|
|
| PLN02670 |
PLN02670 |
transferase, transferring glycosyl groups |
246-413 |
1.30e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 178275 [Multi-domain] Cd Length: 472 Bit Score: 41.43 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 246 TIGKTDIWLIRTYWDFEyprpfPPNFKFVGGLQCKPAKPLA--------------------KELEEFVQSSGDHGIVVFS 305
Cdd:PLN02670 210 AIGGSDVVIIRSSPEFE-----PEWFDLLSDLYRKPIIPIGflppvieddeeddtidvkgwVRIKEWLDKQRVNSVVYVA 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 306 LGSMiKNLTVQKANTIAAALGQISQKVVWRYSGKTPETLAPNTKIYD---------------WIPQNDLLGHPKTKAFIT 370
Cdd:PLN02670 285 LGTE-ASLRREEVTELALGLEKSETPFFWVLRNEPGTTQNALEMLPDgfeervkgrgmihvgWVPQVKILSHESVGGFLT 363
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 221307477 371 HGGTNGLYEAIYHGVPMVGLPLFGDQPDN--LMHLKSKGAAVVLD 413
Cdd:PLN02670 364 HCGWNSVVEGLGFGRVLILFPVLNEQGLNtrLLHGKKLGLEVPRD 408
|
|
| PLN02208 |
PLN02208 |
glycosyltransferase family protein |
353-447 |
1.93e-03 |
|
glycosyltransferase family protein
Pssm-ID: 177858 Cd Length: 442 Bit Score: 40.77 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 353 WIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQP--DNLMHLKSKGAAVV----LDFFTLESkdLVDAL 426
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQVlfTRLMTEEFEVSVEVsrekTGWFSKES--LSNAI 395
|
90 100
....*....|....*....|.
gi 221307477 427 KTVLNNPSykeSIMRLSRIHH 447
Cdd:PLN02208 396 KSVMDKDS---DLGKLVRSNH 413
|
|
| GT28_MurG |
cd03785 |
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ... |
248-446 |
3.16e-03 |
|
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
Pssm-ID: 340818 [Multi-domain] Cd Length: 350 Bit Score: 39.89 E-value: 3.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 248 GKTDIWLIR------TYWDFEYPRPFPPNFKFVGGLQCKPAKPLAKELEEFVQSSGDHGIVVF--SLGSMIKNLTVQKAn 319
Cdd:cd03785 125 GLANRLLSRfadkvaVSFPETKKYFPAAKVVVTGNPVREEILNLRKELKRFGLPPDKPTLLVFggSQGARAINRAVPKA- 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 320 tiAAALGQISQKVVW--------RYSGKTPEtLAPNTKIYDWIPQ-------NDLLghpktkafITHGGTNGLYEAIYHG 384
Cdd:cd03785 204 --LPKLLERGIQVIHqtgkgdydEVKKLYED-LGINVKVFPFIDDmaaayaaADLV--------ISRAGASTIAELTAAG 272
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307477 385 VPMVGLPLF----GDQPDNLMHLKSKGAAVVLDFFTLESKDLVDALKTVLNNP----SYKESIMRLSRIH 446
Cdd:cd03785 273 KPAILIPYPyaadDHQEANARALEKAGAAIVIDQEELTPEVLAEAILDLLNDPerlkKMAEAAKKLAKPD 342
|
|
| Glyco_tran_28_C |
pfam04101 |
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ... |
369-441 |
6.83e-03 |
|
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.
Pssm-ID: 427711 [Multi-domain] Cd Length: 166 Bit Score: 37.69 E-value: 6.83e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 221307477 369 ITHGGTNGLYEAIYHGVPMVGLPL----FGDQPDNLMHLKSKGAAVVLDFFTLESKDLVDALKTVLNNPSYKESIMR 441
Cdd:pfam04101 76 ISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNPLRLAEMAK 152
|
|
| |
