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Conserved domains on  [gi|221307504|ref|NP_001138268|]
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protein C3orf33 homolog [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YncB super family cl43444
Endonuclease YncB, thermonuclease family [Replication, recombination and repair];
114-217 9.99e-05

Endonuclease YncB, thermonuclease family [Replication, recombination and repair];


The actual alignment was detected with superfamily member COG1525:

Pssm-ID: 441134 [Multi-domain]  Cd Length: 164  Bit Score: 41.59  E-value: 9.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307504 114 VRLAGVElTSEGHHWIG----------QQLR---PAETVWLRLIARQNE---TLhCLVSVNkgslfNTCVNEELLRLGLA 177
Cdd:COG1525   48 VRLAGID-APELGQPCGpeqpcgeearQALRallAGKTVTLEPDEGRDRygrLL-AYVYVD-----GRDLNEELVREGLA 120
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 221307504 178 RTSPLVVLDPHSQiywslykRLLRAESKAEKKGKGLWKEE 217
Cdd:COG1525  121 WAYRRYSPDKYAD-------RYLAAEAEARAARRGLWSDA 153
PRK14165 super family cl32962
winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional
67-131 4.88e-03

winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional


The actual alignment was detected with superfamily member PRK14165:

Pssm-ID: 184548 [Multi-domain]  Cd Length: 217  Bit Score: 37.35  E-value: 4.88e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307504  67 RFIERNIIIRGRLRNITEKGLEV---EHIPisvplLSRLLAKRQteallDVRLAGVELT--SEGHHWIGQ 131
Cdd:PRK14165  49 GYITRTIVPRGQLITITEKGLDVlynEYAD-----YSRIFSIKD-----NLELEGNVVKglGEGKYYINI 108
 
Name Accession Description Interval E-value
YncB COG1525
Endonuclease YncB, thermonuclease family [Replication, recombination and repair];
114-217 9.99e-05

Endonuclease YncB, thermonuclease family [Replication, recombination and repair];


Pssm-ID: 441134 [Multi-domain]  Cd Length: 164  Bit Score: 41.59  E-value: 9.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307504 114 VRLAGVElTSEGHHWIG----------QQLR---PAETVWLRLIARQNE---TLhCLVSVNkgslfNTCVNEELLRLGLA 177
Cdd:COG1525   48 VRLAGID-APELGQPCGpeqpcgeearQALRallAGKTVTLEPDEGRDRygrLL-AYVYVD-----GRDLNEELVREGLA 120
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 221307504 178 RTSPLVVLDPHSQiywslykRLLRAESKAEKKGKGLWKEE 217
Cdd:COG1525  121 WAYRRYSPDKYAD-------RYLAAEAEARAARRGLWSDA 153
SNc cd00175
Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and ...
167-216 1.78e-04

Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds.


Pssm-ID: 238102  Cd Length: 129  Bit Score: 40.34  E-value: 1.78e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 221307504 167 VNEELLRLGLARtsplvVLDPHSQiYWSLYKRLLRAESKAEKKGKGLWKE 216
Cdd:cd00175   86 IAEELVKEGLAR-----VYRYYPD-DSEYYDELLEAEEAAKKARKGLWSD 129
SNase pfam00565
Staphylococcal nuclease homolog; Present in all three domains of cellular life. Four copies in ...
164-216 2.64e-04

Staphylococcal nuclease homolog; Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.


Pssm-ID: 395448  Cd Length: 106  Bit Score: 39.23  E-value: 2.64e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 221307504  164 NTCVNEELLRLGLARTSPLV-VLDPHsqiywslYKRLLRAESKAEKKGKGLWKE 216
Cdd:pfam00565  60 GKNINEELVKEGLAWVYKAYpPNFKH-------YDELLAAEEEAKKKKKGLWSD 106
PRK14165 PRK14165
winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional
67-131 4.88e-03

winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional


Pssm-ID: 184548 [Multi-domain]  Cd Length: 217  Bit Score: 37.35  E-value: 4.88e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307504  67 RFIERNIIIRGRLRNITEKGLEV---EHIPisvplLSRLLAKRQteallDVRLAGVELT--SEGHHWIGQ 131
Cdd:PRK14165  49 GYITRTIVPRGQLITITEKGLDVlynEYAD-----YSRIFSIKD-----NLELEGNVVKglGEGKYYINI 108
SNc smart00318
Staphylococcal nuclease homologues;
167-216 5.38e-03

Staphylococcal nuclease homologues;


Pssm-ID: 214615  Cd Length: 137  Bit Score: 36.09  E-value: 5.38e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 221307504   167 VNEELLRLGLARTSPLVVLDPHSqiywslYKRLLRAESKAEKKGKGLWKE 216
Cdd:smart00318  94 IAEELVKEGLAKVYRYADKDEYV------YDELLEAEEAAKKARKGLWSD 137
 
Name Accession Description Interval E-value
YncB COG1525
Endonuclease YncB, thermonuclease family [Replication, recombination and repair];
114-217 9.99e-05

Endonuclease YncB, thermonuclease family [Replication, recombination and repair];


Pssm-ID: 441134 [Multi-domain]  Cd Length: 164  Bit Score: 41.59  E-value: 9.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307504 114 VRLAGVElTSEGHHWIG----------QQLR---PAETVWLRLIARQNE---TLhCLVSVNkgslfNTCVNEELLRLGLA 177
Cdd:COG1525   48 VRLAGID-APELGQPCGpeqpcgeearQALRallAGKTVTLEPDEGRDRygrLL-AYVYVD-----GRDLNEELVREGLA 120
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 221307504 178 RTSPLVVLDPHSQiywslykRLLRAESKAEKKGKGLWKEE 217
Cdd:COG1525  121 WAYRRYSPDKYAD-------RYLAAEAEARAARRGLWSDA 153
SNc cd00175
Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and ...
167-216 1.78e-04

Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds.


Pssm-ID: 238102  Cd Length: 129  Bit Score: 40.34  E-value: 1.78e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 221307504 167 VNEELLRLGLARtsplvVLDPHSQiYWSLYKRLLRAESKAEKKGKGLWKE 216
Cdd:cd00175   86 IAEELVKEGLAR-----VYRYYPD-DSEYYDELLEAEEAAKKARKGLWSD 129
SNase pfam00565
Staphylococcal nuclease homolog; Present in all three domains of cellular life. Four copies in ...
164-216 2.64e-04

Staphylococcal nuclease homolog; Present in all three domains of cellular life. Four copies in the transcriptional coactivator p100: these, however, appear to lack the active site residues of Staphylococcal nuclease. Positions 14 (Asp-21), 34 (Arg-35), 39 (Asp-40), 42 (Glu-43) and 110 (Arg-87) [SNase numbering in parentheses] are thought to be involved in substrate-binding and catalysis.


Pssm-ID: 395448  Cd Length: 106  Bit Score: 39.23  E-value: 2.64e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 221307504  164 NTCVNEELLRLGLARTSPLV-VLDPHsqiywslYKRLLRAESKAEKKGKGLWKE 216
Cdd:pfam00565  60 GKNINEELVKEGLAWVYKAYpPNFKH-------YDELLAAEEEAKKKKKGLWSD 106
PRK14165 PRK14165
winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional
67-131 4.88e-03

winged helix-turn-helix domain-containing protein/riboflavin kinase; Provisional


Pssm-ID: 184548 [Multi-domain]  Cd Length: 217  Bit Score: 37.35  E-value: 4.88e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221307504  67 RFIERNIIIRGRLRNITEKGLEV---EHIPisvplLSRLLAKRQteallDVRLAGVELT--SEGHHWIGQ 131
Cdd:PRK14165  49 GYITRTIVPRGQLITITEKGLDVlynEYAD-----YSRIFSIKD-----NLELEGNVVKglGEGKYYINI 108
SNc smart00318
Staphylococcal nuclease homologues;
167-216 5.38e-03

Staphylococcal nuclease homologues;


Pssm-ID: 214615  Cd Length: 137  Bit Score: 36.09  E-value: 5.38e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 221307504   167 VNEELLRLGLARTSPLVVLDPHSqiywslYKRLLRAESKAEKKGKGLWKE 216
Cdd:smart00318  94 IAEELVKEGLAKVYRYADKDEYV------YDELLEAEEAAKKARKGLWSD 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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