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Conserved domains on  [gi|221330874|ref|NP_001137889|]
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farmer, isoform J [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
rne super family cl35953
ribonuclease E; Reviewed
634-751 5.02e-07

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 53.50  E-value: 5.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTEAPLEEKASEPVAAASEEVktlVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAA--VEPKPVASEE 711
Cdd:PRK10811  858 QREAEEVQVQPVVAEVPVAAAVEP---VVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAApvTEQPQVITES 934
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 221330874  712 VKAPAESVPAASEEVKVKVEPEAEKVLADPKPETKVTSET 751
Cdd:PRK10811  935 DVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPE 974
 
Name Accession Description Interval E-value
rne PRK10811
ribonuclease E; Reviewed
634-751 5.02e-07

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 53.50  E-value: 5.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTEAPLEEKASEPVAAASEEVktlVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAA--VEPKPVASEE 711
Cdd:PRK10811  858 QREAEEVQVQPVVAEVPVAAAVEP---VVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAApvTEQPQVITES 934
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 221330874  712 VKAPAESVPAASEEVKVKVEPEAEKVLADPKPETKVTSET 751
Cdd:PRK10811  935 DVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPE 974
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
632-746 1.76e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 44.45  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  632 KREATDTEAPLEEKASEP---VAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEpkpvA 708
Cdd:TIGR02794  63 AKKEQERQKKLEQQAEEAekqRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAE----A 138
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 221330874  709 SEEVKAPAESVPAASEEVKVKVEPEAEK----VLADPKPETK 746
Cdd:TIGR02794 139 EAERKAKEEAAKQAEEEAKAKAAAEAKKkaeeAKKKAEAEAK 180
 
Name Accession Description Interval E-value
rne PRK10811
ribonuclease E; Reviewed
634-751 5.02e-07

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 53.50  E-value: 5.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTEAPLEEKASEPVAAASEEVktlVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAA--VEPKPVASEE 711
Cdd:PRK10811  858 QREAEEVQVQPVVAEVPVAAAVEP---VVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAApvTEQPQVITES 934
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 221330874  712 VKAPAESVPAASEEVKVKVEPEAEKVLADPKPETKVTSET 751
Cdd:PRK10811  935 DVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPE 974
rne PRK10811
ribonuclease E; Reviewed
634-747 1.38e-06

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 51.96  E-value: 1.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTEAPLEEKASEPVAAASEEVktLVEPVPAASEVSKAEVEPAA---ASEVSKVDVEPAAAASEEVKAAVEPKPVASE 710
Cdd:PRK10811  896 EEPVVVAEPQPEEVVVVETTHPEV--IAAPVTEQPQVITESDVAVAqevAEHAEPVVEPQDETADIEEAAETAEVVVAEP 973
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 221330874  711 EVKAPAESVPAASEEVKVKVEPEAEKVLADPKPETKV 747
Cdd:PRK10811  974 EVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEAT 1010
rne PRK10811
ribonuclease E; Reviewed
634-750 2.31e-06

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 51.19  E-value: 2.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTEAPLEEKASEPVAAASEEVKtlVEPV-------PAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEPKP 706
Cdd:PRK10811  871 AEVPVAAAVEPVVSAPVVEAVAEVV--EEPVvvaepqpEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEP 948
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 221330874  707 VASEEVKAPAESVPAASEEVKVkVEPEAEKVLADPKPETKVTSE 750
Cdd:PRK10811  949 VVEPQDETADIEEAAETAEVVV-AEPEVVAQPAAPVVAEVAAEV 991
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
631-750 4.36e-06

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 49.80  E-value: 4.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 631 KKREATDTEAPLEEKASEPVAAASEEV---KTLVEPVPAASEVSKAEVEpAAASEVSKVDVEPAAAASEEVKAAVEPKPV 707
Cdd:PRK09510 118 KQAEEAAKQAALKQKQAEEAAAKAAAAakaKAEAEAKRAAAAAKKAAAE-AKKKAEAEAAKKAAAEAKKKAEAEAAAKAA 196
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 221330874 708 ASEEVKAPAESVPAASEEVKVKVEPEAEKVLADPKPETKVTSE 750
Cdd:PRK09510 197 AEAKKKAEAEAKKKAAAEAKKKAAAEAKAAAAKAAAEAKAAAE 239
rne PRK10811
ribonuclease E; Reviewed
643-751 1.25e-05

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 48.88  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  643 EEKASEPVAAASEEVKTL--VEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAA--VEPKPVASEE-----VK 713
Cdd:PRK10811  862 EEVQVQPVVAEVPVAAAVepVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAApvTEQPQVITESdvavaQE 941
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 221330874  714 APAESVPAASEEVKVKVEPEAEKVLADPKPETKVTSET 751
Cdd:PRK10811  942 VAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQP 979
PTZ00121 PTZ00121
MAEBL; Provisional
628-750 3.68e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 3.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  628 RLHKKREATDTEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEPKPV 707
Cdd:PTZ00121 1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKI 1730
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 221330874  708 ASEEVKAPAESVPAASEEVKVKvEPEAEKVLADPKPETKVTSE 750
Cdd:PTZ00121 1731 KAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEE 1772
PTZ00121 PTZ00121
MAEBL; Provisional
631-742 7.20e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 7.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  631 KKREATDTEAPLE--EKASEPVAAASEEVKTLVEPVPA--ASEVSKAEVEPAAASEVSKvdvepaaaaSEEVKAAVEPKP 706
Cdd:PTZ00121 1569 AKKAEEDKNMALRkaEEAKKAEEARIEEVMKLYEEEKKmkAEEAKKAEEAKIKAEELKK---------AEEEKKKVEQLK 1639
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 221330874  707 VASEEVKAPAESVPAASEEVKVKVEPEAEKVLADPK 742
Cdd:PTZ00121 1640 KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKK 1675
rne PRK10811
ribonuclease E; Reviewed
638-746 7.44e-05

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 46.19  E-value: 7.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  638 TEAPLEEKASEPVAAASEEVKTLVEP--VPAASEVSkAEVEPAAASEVSKVDVEPAAAASEEVkaAVEPKPVASEEVkaP 715
Cdd:PRK10811  908 EVVVVETTHPEVIAAPVTEQPQVITEsdVAVAQEVA-EHAEPVVEPQDETADIEEAAETAEVV--VAEPEVVAQPAA--P 982
                          90       100       110
                  ....*....|....*....|....*....|.
gi 221330874  716 AESVPAASEEVKVKVEPEAEKVLADPKPETK 746
Cdd:PRK10811  983 VVAEVAAEVETVTAVEPEVAPAQVPEATVEH 1013
rne PRK10811
ribonuclease E; Reviewed
634-729 7.57e-05

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 46.19  E-value: 7.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTE---APLEEKA---SEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVskVDVEPAAAASEEVKAAVEPKPV 707
Cdd:PRK10811  913 ETTHPEviaAPVTEQPqviTESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEV--VVAEPEVVAQPAAPVVAEVAAE 990
                          90       100
                  ....*....|....*....|..
gi 221330874  708 ASEEVKAPAESVPAASEEVKVK 729
Cdd:PRK10811  991 VETVTAVEPEVAPAQVPEATVE 1012
PTZ00121 PTZ00121
MAEBL; Provisional
631-750 8.60e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 8.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  631 KKREATDTEAPLEEKASEPVAAASEEVKtlvepVPAASEVSKAEVEPAAASEVSKVDVEPAAAA------SEEVKAAVEP 704
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEELKKAEEENK-----IKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAealkkeAEEAKKAEEL 1707
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 221330874  705 KPVASEEVKApAESVPAASEEVKVKVEPEAEKVLADPKP--ETKVTSE 750
Cdd:PTZ00121 1708 KKKEAEEKKK-AEELKKAEEENKIKAEEAKKEAEEDKKKaeEAKKDEE 1754
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
632-746 1.76e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 44.45  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  632 KREATDTEAPLEEKASEP---VAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEpkpvA 708
Cdd:TIGR02794  63 AKKEQERQKKLEQQAEEAekqRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAE----A 138
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 221330874  709 SEEVKAPAESVPAASEEVKVKVEPEAEK----VLADPKPETK 746
Cdd:TIGR02794 139 EAERKAKEEAAKQAEEEAKAKAAAEAKKkaeeAKKKAEAEAK 180
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
638-743 1.83e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.71  E-value: 1.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 638 TEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEPKPVaseevkAPAE 717
Cdd:PRK14951 378 KKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVAL------APAP 451
                         90       100
                 ....*....|....*....|....*.
gi 221330874 718 SVPAASEEVKVKVEPEAEKVLADPKP 743
Cdd:PRK14951 452 PAQAAPETVAIPVRVAPEPAVASAAP 477
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
646-749 1.83e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.71  E-value: 1.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 646 ASEPVAAASEEVKTLVEPV---PAASEVSKAEVEPAAASEVSKVDVEPAAAAseevkAAVEPKPVASEEVKAPA---ESV 719
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEaaaPAAAPVAQAAAAPAPAAAPAAAASAPAAPP-----AAAPPAPVAAPAAAAPAaapAAA 441
                         90       100       110
                 ....*....|....*....|....*....|...
gi 221330874 720 PAASEEVKVKVEPEAEKVLADPK---PETKVTS 749
Cdd:PRK14951 442 PAAVALAPAPPAQAAPETVAIPVrvaPEPAVAS 474
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
631-736 3.07e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 43.64  E-value: 3.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 631 KKREATDTEAPLEEKASEPVAAASEE---VKTLVEPVPAASEVSKAEVEPAAASEVSKvDVEPAAAASEEVKAAVEPKPV 707
Cdd:PRK09510 140 KAAAAAKAKAEAEAKRAAAAAKKAAAeakKKAEAEAAKKAAAEAKKKAEAEAAAKAAA-EAKKKAEAEAKKKAAAEAKKK 218
                         90       100
                 ....*....|....*....|....*....
gi 221330874 708 ASEEVKAPAEsvpAASEEVKVKVEPEAEK 736
Cdd:PRK09510 219 AAAEAKAAAA---KAAAEAKAAAEKAAAA 244
rne PRK10811
ribonuclease E; Reviewed
635-748 3.47e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 44.26  E-value: 3.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  635 ATDTEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAAsevskVDVEPAAAASEEVKAAVEPKPVASEEVKA 714
Cdd:PRK10811  848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAE-----VVEEPVVVAEPQPEEVVVVETTHPEVIAA 922
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 221330874  715 PAESVPAASEE----VKVKVEPEAEKVLADPKPETKVT 748
Cdd:PRK10811  923 PVTEQPQVITEsdvaVAQEVAEHAEPVVEPQDETADIE 960
PTZ00121 PTZ00121
MAEBL; Provisional
629-740 4.16e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 4.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  629 LHKKREATDTEAPLEEKASEPVAAAsEEVKTLVEPVPAASEVSKAEVEPAA-ASEVSKVDVEPAAAASEEVKAAVEPKPV 707
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKAEEAKKKA-DAAKKKAEEAKKAAEAAKAEAEAAAdEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 221330874  708 ASEEVKApAESVPAASEEVKVKVE----PEAEKVLAD 740
Cdd:PTZ00121 1386 KAEEKKK-ADEAKKKAEEDKKKADelkkAAAAKKKAD 1421
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
634-744 4.23e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 43.70  E-value: 4.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 634 EATDTEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAASevskvDVEPAAAASEEVkAAVEPKPVASEEVK 713
Cdd:PRK07994 400 PPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAAS-----RARPVNSALERL-ASVRPAPSALEKAP 473
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 221330874 714 APAE-----SVPAASEEVKVKVEPEAEK--VLADPKPE 744
Cdd:PRK07994 474 AKKEayrwkATNPVEVKKEPVATPKALKkaLEHEKTPE 511
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
645-732 4.27e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 43.40  E-value: 4.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 645 KASEPVAAASEEVKTLVEPVPAASEVSKAEVEPA-AASEVSKVDVEPAAAASEEVKAAVEPKPVASEEVKAPAESVPAAS 723
Cdd:PTZ00436 218 KAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAkAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAA 297

                 ....*....
gi 221330874 724 EEVKVKVEP 732
Cdd:PTZ00436 298 APAKAAAAP 306
PTZ00121 PTZ00121
MAEBL; Provisional
631-750 5.46e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 5.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  631 KKREATDTEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSK-AEVEPAAASEVSKVDVEPAAA-----ASEEVKAAVEP 704
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKkAEEDKKKADELKKAAAAKKKAdeakkKAEEKKKADEA 1436
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 221330874  705 KPVASE-----EVKAPAESVPAAsEEVKVKVEPEAEKVLADPKPETKVTSE 750
Cdd:PTZ00121 1437 KKKAEEakkadEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKKAEEAKKAD 1486
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
639-751 7.21e-04

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 42.66  E-value: 7.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 639 EAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEPKPVASEEVKAP--A 716
Cdd:PRK13108 322 EPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEADIEREQPGDLAGQAPAAHQVDAEAASAAPeeP 401
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 221330874 717 ESVPAASEEVKVKVEPEAEKVLADP-KPETKVTSET 751
Cdd:PRK13108 402 AALASEAHDETEPEVPEKAAPIPDPaKPDELAVAGP 437
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
638-732 8.14e-04

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 42.24  E-value: 8.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 638 TEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPA-AASEVSKVDVEPAAAASEEVKAAVEPKPVASEEVKAPA 716
Cdd:PTZ00436 232 AAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAkAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAA 311
                         90
                 ....*....|....*.
gi 221330874 717 ESVPAASEEVKVKVEP 732
Cdd:PTZ00436 312 APAKAAAPPAKAAAPP 327
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
640-736 1.18e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.86  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 640 APLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPA-AASEVSKVDVEPAAAASEEVKAAVEPKPVASEEVKAPAES 718
Cdd:PTZ00436 255 APPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAkAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPP 334
                         90
                 ....*....|....*...
gi 221330874 719 VPAASEEVKVKVEPEAEK 736
Cdd:PTZ00436 335 AKAAAPPAKAAAAPVGKK 352
PTZ00121 PTZ00121
MAEBL; Provisional
631-736 1.23e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  631 KKREATDTEAPLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEVKAAVEPKPVASE 710
Cdd:PTZ00121 1613 KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692
                          90       100
                  ....*....|....*....|....*.
gi 221330874  711 EVKAPAESVPAAsEEVKVKVEPEAEK 736
Cdd:PTZ00121 1693 ALKKEAEEAKKA-EELKKKEAEEKKK 1717
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
640-732 1.32e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.86  E-value: 1.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 640 APLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPA-AASEVSKVDVEPAAAASEEVKAAVEPKPVASEEVKAPAES 718
Cdd:PTZ00436 248 AAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAkAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPPAKAAAPP 327
                         90
                 ....*....|....
gi 221330874 719 VPAASEEVKVKVEP 732
Cdd:PTZ00436 328 AKAATPPAKAAAPP 341
PTZ00436 PTZ00436
60S ribosomal protein L19-like protein; Provisional
640-732 1.96e-03

60S ribosomal protein L19-like protein; Provisional


Pssm-ID: 185616 [Multi-domain]  Cd Length: 357  Bit Score: 41.09  E-value: 1.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 640 APLEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPA-AASEVSKVDVEPAAAASEEVKAAVEPKPVASEEVKAPAES 718
Cdd:PTZ00436 241 AAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAkAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAPAKAAAPP 320
                         90
                 ....*....|....
gi 221330874 719 VPAASEEVKVKVEP 732
Cdd:PTZ00436 321 AKAAAPPAKAATPP 334
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
628-736 2.08e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 41.33  E-value: 2.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 628 RLHKKREATDTEaplEEKASEPVAAASEEVKTLVEPVPAASEVSKAEVEPAAAsevskvdVEPAAAASEE----VKAAVE 703
Cdd:PRK09510 105 QLEKERLAAQEQ---KKQAEEAAKQAALKQKQAEEAAAKAAAAAKAKAEAEAK-------RAAAAAKKAAaeakKKAEAE 174
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 221330874 704 PKPVASEEVKAPAESVPA--ASEEVKVKVEPEAEK 736
Cdd:PRK09510 175 AAKKAAAEAKKKAEAEAAakAAAEAKKKAEAEAKK 209
PRK12373 PRK12373
NADH-quinone oxidoreductase subunit E;
564-745 3.77e-03

NADH-quinone oxidoreductase subunit E;


Pssm-ID: 237082 [Multi-domain]  Cd Length: 400  Bit Score: 40.56  E-value: 3.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 564 PVVILPQEYYSNCEENSINQLtnIDSFPLGVQPGVSFSLHSVLTGSAPKDQcmcPCSCTQNLPnrlhkkREATDTEAPLE 643
Cdd:PRK12373 145 PMVQIGKDYYEDLTPERLEEI--IDAFAAGKGPVVKPGPQIGRYASEPAGG---LTSLTEEAG------KARYNASKALA 213
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 644 EKASEPVAAA-SEEVKTLVEPVPAASEVSKAE--------VEPAAASEVSKVdvEPAAAASEevKAAVEPKPVASEEVKA 714
Cdd:PRK12373 214 EDIGDTVKRIdGTEVPLLAPWQGDAAPVPPSEaarpksadAETNAALKTPAT--APKAAAKN--AKAPEAQPVSGTAAAE 289
                        170       180       190
                 ....*....|....*....|....*....|..
gi 221330874 715 PAESVPAASEEVKVK-VEPEAEKVLADPKPET 745
Cdd:PRK12373 290 PAPKEAAKAAAAAAKpALEDKPRPLGIARPGG 321
rne PRK10811
ribonuclease E; Reviewed
650-752 4.77e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.41  E-value: 4.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  650 VAAASEEV---KTLVE-PVPAASEVSKAEVEPAAASEVSKVDVEPAAAASEEvkaAVEPKPVASEEVKAPAESVPAASEE 725
Cdd:PRK10811  829 VACASPEMasgKVWIRyPVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVE---PVVSAPVVEAVAEVVEEPVVVAEPQ 905
                          90       100       110
                  ....*....|....*....|....*....|
gi 221330874  726 VK--VKVEPEAEKVLADPKPE-TKVTSETN 752
Cdd:PRK10811  906 PEevVVVETTHPEVIAAPVTEqPQVITESD 935
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
626-736 5.86e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 39.44  E-value: 5.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  626 PNRLhkKREATDTEAPLEEKASEPVAAASEEVKTlvepvPAASEVSKAEVEPAAASEVSKVDVEPAA-AASEEVKAAVEP 704
Cdd:TIGR02794  52 ANRI--QQQKKPAAKKEQERQKKLEQQAEEAEKQ-----RAAEQARQKELEQRAAAEKAAKQAEQAAkQAEEKQKQAEEA 124
                          90       100       110
                  ....*....|....*....|....*....|....
gi 221330874  705 KPVASEEVKAPAESV--PAASEEVKVKVEPEAEK 736
Cdd:TIGR02794 125 KAKQAAEAKAKAEAEaeRKAKEEAAKQAEEEAKA 158
flhF PRK06995
flagellar biosynthesis protein FlhF;
648-743 7.07e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 39.56  E-value: 7.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874 648 EPVAAASEEVKTLVEPVPAASEVSKAEVEPAAAsevskVDVEPAAAASEEVKAAVEPKPVASEEVKAPAESVPAASEEVK 727
Cdd:PRK06995  39 EIVALADSDLAALAPPAAAAPAAAQPPPAAAPA-----AVSRPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEA 113
                         90
                 ....*....|....*.
gi 221330874 728 VKVEPEAEKVLADPKP 743
Cdd:PRK06995 114 QAPAAPAERAAAENAA 129
L12 TIGR00855
ribosomal protein L7/L12; Ribosomal proteins L7 and L12 are synonymous except for ...
634-731 8.08e-03

ribosomal protein L7/L12; Ribosomal proteins L7 and L12 are synonymous except for post-translational modification of the N-terminal amino acid. THis model resembles pfam00542 but matches the full length of prokaryotic and organellar proteins rather than just the C-terminus. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273301 [Multi-domain]  Cd Length: 123  Bit Score: 37.05  E-value: 8.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  634 EATDTEAPLEEK----ASEPVAAASEEVKTLVEPVPAASEVSkAEVEPAAAS--EVSKVDVEPAAAASEEVKAAVE--PK 705
Cdd:TIGR00855  17 ELSELVKALEEKfgvsAAAPVAAGAAGAAAGAAAAEEKTEFD-VILKGAGDNkiAVIKVVREITGLGLKEAKDLVEgaPK 95
                          90       100
                  ....*....|....*....|....*.
gi 221330874  706 PVASEEVKAPAESVPAASEEVKVKVE 731
Cdd:TIGR00855  96 ALKEGVSKEEAEELKKKLEEAGAKVE 121
rne PRK10811
ribonuclease E; Reviewed
633-722 9.91e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 39.25  E-value: 9.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330874  633 REATDTEAPLEEKASEPVAAASEEVKTLVEPVPAASE-------VSKAEVEPAAASEVSKVD--VEPAAAASEEVKAAVE 703
Cdd:PRK10811  932 TESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVvvaepevVAQPAAPVVAEVAAEVETvtAVEPEVAPAQVPEATV 1011
                          90       100
                  ....*....|....*....|.
gi 221330874  704 PKPVASEEV-KAPA-ESVPAA 722
Cdd:PRK10811 1012 EHNHATAPMtRAPApEYVPEA 1032
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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