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Conserved domains on  [gi|221330346|ref|NP_001137686|]
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uncharacterized protein Dmel_CG30460, isoform G [Drosophila melanogaster]

Protein Classification

C2HC-type zinc finger protein( domain architecture ID 10621545)

C2HC-type zinc finger protein similar to Homo sapiens zinc finger protein 474 (ZNF474), a testis-specific zinc finger protein

CATH:  4.10.320.30
Gene Ontology:  GO:0008270
PubMed:  1280325|17210253|12665246
SCOP:  4003606

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 250-274 5.88e-07

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


:

Pssm-ID: 464037  Cd Length: 25  Bit Score: 46.80  E-value: 5.88e-07
                           10        20
                   ....*....|....*....|....*
gi 221330346   250 QLTPCPCCSRTFAVDTLRKHVVICE 274
Cdd:pfam13913    1 ELVPCPICGRTFNPDRLAKHEKICK 25
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 414-435 5.03e-04

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


:

Pssm-ID: 464037  Cd Length: 25  Bit Score: 38.71  E-value: 5.03e-04
                           10        20
                   ....*....|....*....|..
gi 221330346   414 RCPHCDRTFNPKAFDRHVEWCK 435
Cdd:pfam13913    4 PCPICGRTFNPDRLAKHEKICK 25
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1190-1291 9.15e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330346 1190 GSSGGRGEEAQRSSSGLPAPNPTHQVVAS-SPSADSDELSSLDGYPMSSSQGSRRGASSKLSTDSAYGSSNSPYSLSRQR 1268
Cdd:PHA03307  289 SSPRERSPSPSPSSPGSGPAPSSPRASSSsSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368

                          90       100
                  ....*....|....*....|...
gi 221330346 1269 SSELQAGTLQSQGLMRPHTASAK 1291
Cdd:PHA03307  369 PRPSRAPSSPAASAGRPTRRRAR 391
 
Name Accession Description Interval E-value
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 250-274 5.88e-07

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 46.80  E-value: 5.88e-07
                           10        20
                   ....*....|....*....|....*
gi 221330346   250 QLTPCPCCSRTFAVDTLRKHVVICE 274
Cdd:pfam13913    1 ELVPCPICGRTFNPDRLAKHEKICK 25
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 414-435 5.03e-04

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 38.71  E-value: 5.03e-04
                           10        20
                   ....*....|....*....|..
gi 221330346   414 RCPHCDRTFNPKAFDRHVEWCK 435
Cdd:pfam13913    4 PCPICGRTFNPDRLAKHEKICK 25
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1190-1291 9.15e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330346 1190 GSSGGRGEEAQRSSSGLPAPNPTHQVVAS-SPSADSDELSSLDGYPMSSSQGSRRGASSKLSTDSAYGSSNSPYSLSRQR 1268
Cdd:PHA03307  289 SSPRERSPSPSPSSPGSGPAPSSPRASSSsSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368

                          90       100
                  ....*....|....*....|...
gi 221330346 1269 SSELQAGTLQSQGLMRPHTASAK 1291
Cdd:PHA03307  369 PRPSRAPSSPAASAGRPTRRRAR 391
 
Name Accession Description Interval E-value
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 250-274 5.88e-07

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 46.80  E-value: 5.88e-07
                           10        20
                   ....*....|....*....|....*
gi 221330346   250 QLTPCPCCSRTFAVDTLRKHVVICE 274
Cdd:pfam13913    1 ELVPCPICGRTFNPDRLAKHEKICK 25
zf-C2HC_2 pfam13913
zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.
 414-435 5.03e-04

zinc-finger of a C2HC-type; This family contains a number of divergent C2H2 type zinc fingers.


Pssm-ID: 464037  Cd Length: 25  Bit Score: 38.71  E-value: 5.03e-04
                           10        20
                   ....*....|....*....|..
gi 221330346   414 RCPHCDRTFNPKAFDRHVEWCK 435
Cdd:pfam13913    4 PCPICGRTFNPDRLAKHEKICK 25
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1190-1291 9.15e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 9.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221330346 1190 GSSGGRGEEAQRSSSGLPAPNPTHQVVAS-SPSADSDELSSLDGYPMSSSQGSRRGASSKLSTDSAYGSSNSPYSLSRQR 1268
Cdd:PHA03307  289 SSPRERSPSPSPSSPGSGPAPSSPRASSSsSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368

                          90       100
                  ....*....|....*....|...
gi 221330346 1269 SSELQAGTLQSQGLMRPHTASAK 1291
Cdd:PHA03307  369 PRPSRAPSSPAASAGRPTRRRAR 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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