NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

827-1066

7.15e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.51 E-value: 7.15e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  827 QLLDALEEARTKHEQIETSIRESCAQDRE-AIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDR-LQSELRQ 904
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIaRLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  905 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHYR 984
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAE-----AEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  985 AERDRQLDELVvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQL 1064
Cdd:COG1196   387 ELLEALRAAAE---LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463


                  ..
gi 386767627 1065 EL 1066
Cdd:COG1196   464 LL 465

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

783-1151

8.80e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.25 E-value: 8.80e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   783 RERWVRENTKKIKELTVKGLEAEInkmncdhqrEVTELKRTHQmQLLDALEEARTKHEQIETSIREscAQDREAIIEKER 862
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEK---------ALAELRKELE-ELEEELEQLRKELEELSRQISA--LRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   863 TAIRERFERQ------LEEEQRTQAEQRQKLTEEFAA---ERDRLQSELRQRENEHQArrqeaLREQEQELEQAKFEMQE 933
Cdd:TIGR02168  743 EQLEERIAQLskelteLEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA-----LREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   934 RMAKQEEKYQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVrmeadALQHKEEHELKM 1013
Cdd:TIGR02168  818 EAANLRERLESLERRIAATER---RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1014 NRLKEKYEK---DLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1090
Cdd:TIGR02168  890 ALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767627  1091 IQ----------SELGVLNERHKQEMDQLQKRvHQTIQRQEETIEILKGDndaLRQQCLKLNAVIRQQRKD 1151
Cdd:TIGR02168  970 ARrrlkrlenkiKELGPVNLAAIEEYEELKER-YDFLTAQKEDLTEAKET---LEEAIEEIDREARERFKD 1036

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

754-1050

3.20e-11

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 67.84 E-value: 3.20e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   754 ESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKG-LEAEINKMNCDHQREVT---------ELKRT 823
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaIYAEQERMAMERERELErirqeerkrELERI 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   824 HQMQL------LDALEEARTKHEQIETSIRESC-AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD 896
Cdd:pfam17380  366 RQEEIameisrMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   897 RLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwKTEHENKTKLAQAEKE 976
Cdd:pfam17380  446 REMERVRLEEQERQ-QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA-MIEEERKRKLLEKEME 523

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767627   977 NAIRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEADA 1050
Cdd:pfam17380  524 ERQKAIYEEERRREAEE--ERRKQQEMEERRRIQEQMRKATE--ERSRLEAMEREREMMRQIVESEKARAEYEA 593

PTZ00121

MAEBL; Provisional

698-1072

1.07e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 1.07e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  698 EKQKSLRAEKSTAAAKLR-DQKKHYEEVVTRHQGFIEQLLKDKGSLCEKvAALTRRLESQNQAWEHRLETELARTKETTM 776
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAKK-AEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  777 AGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSirescaqdrea 856
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA----------- 1628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  857 iiEKERTAIRERfeRQLEEEQRTQAEQRQKlteefAAERDRLQSELRQRENEHQARRQEALREQEQElEQAKFEMQERMA 936
Cdd:PTZ00121 1629 --EEEKKKVEQL--KKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEA 1698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  937 KQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnAIRQHYRAERDRQLDElvvrmEADALQHKEEHELKMNRL 1016
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-AEEDKKKAEEAKKDEE-----EKKKIAHLKKEEEKKAEE 1772

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627 1017 KEKyEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKM 1072
Cdd:PTZ00121 1773 IRK-EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

700-941

5.48e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 5.48e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  700 QKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhRLETELARTkETTMAGE 779
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-ALEAELAEL-EKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  780 KIRRERWVRENTKKIKELTVKGLEAEINKMNcdHQREVTELKRThqMQLLDALEEARTkhEQIETsiresCAQDREAIIE 859
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLL--SPEDFLDAVRR--LQYLKYLAPARR--EQAEE-----LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  860 KERTAIRERfeRQLEEEQRTQAEQRQKLTEEfAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQE 939
Cdd:COG4942   165 LRAELEAER--AELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAE-LQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 386767627  940 EK 941
Cdd:COG4942   241 ER 242

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

666-948

1.57e-05

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.98 E-value: 1.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   666 QLARRVIALSLRANElaNAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRH----QGFIEQLLKDKGS 741
Cdd:pfam09731  139 SKAESATAVAKEAKD--DAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVInlakQSEEEAAPPLLDA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   742 LCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKirRERWVRENTKKIKELTV------KGLEAEINKMNCDHQR 815
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASE--RIVFQQELVSIFPDIIPvlkednLLSNDDLNSLIAHAHR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   816 EVTELKRthQMQLLDALEEARtkheqIETSIRESCAQDREAIiEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFaaeR 895
Cdd:pfam09731  295 EIDQLSK--KLAELKKREEKH-----IERALEKQKEELDKLA-EELSARLEEVRAADEAQLRLEFEREREEIRESY---E 363

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 386767627   896 DRLQSELRQRENEHQARRQEALREQEQELE-QAKFEMQERMAKQEEKYQNRVNT 948
Cdd:pfam09731  364 EKLRTELERQAEAHEEHLKDVLVEQEIELQrEFLQDIKEKVEEERAGRLLKLNE 417

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

999-1150

6.23e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 6.23e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  999 EADALQHK-EEHELKMNRLKEKYekDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDI- 1076
Cdd:COG3206   183 QLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1077 ----IMERDRLRDNLNADIQSELGVLNERH------KQEMDQLQKRVHQTIQRQEETIEIlkgDNDALRQQCLKLNAVIR 1146
Cdd:COG3206   261 qspvIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEA---ELEALQAREASLQAQLA 337


                  ....
gi 386767627 1147 QQRK 1150
Cdd:COG3206   338 QLEA 341

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

826-938

1.37e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 45.26 E-value: 1.37e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  826 MQLLDALEEA--RTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRTQAEQRQKLTEEFAAERDRLQS 900
Cdd:cd16269   176 LQSKEAEAEAilQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQrelEQKLEDQERSYEEHLRQLKEKMEEERENLLK 255

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 386767627  901 ELrQRENEHQarrqeaLREQEQELEQAKFEMQERMAKQ 938
Cdd:cd16269   256 EQ-ERALESK------LKEQEALLEEGFKEQAELLQEE 286

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

666-957

1.63e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.20 E-value: 1.63e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   666 QLARRVIALSLRANELANAIHMSKEHVFQLRG---------EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLL 736
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   737 KDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRrerwvrENTKKIKELT--VKGLEAEINKMNCDHQ 814
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE------ELESELEALLneRASLEEALALLRSELE 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   815 REVTELK--RTHQMQLLDALEEARTKHEQIETsirescaqdREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFA 892
Cdd:TIGR02168  898 ELSEELRelESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627   893 AERDRLqSELRQR-------------ENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF 957
Cdd:TIGR02168  969 EARRRL-KRLENKikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENF 1045

growth_prot_Scy

NF041483

polarized growth protein Scy;

750-1062

1.84e-04

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 45.97 E-value: 1.84e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  750 TRRLESQNQAWEHRLETELARTkETTMAGEKIRRERwVRENTKKIKE--------LTVKGLEAE--INKMNCDHQR---E 816
Cdd:NF041483  433 AKTVELQEEARRLRGEAEQLRA-EAVAEGERIRGEA-RREAVQQIEEaartaeelLTKAKADADelRSTATAESERvrtE 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  817 VTELKRTHQMQLLDALEEARTKHEQIETsirESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQkltEEFAAERD 896
Cdd:NF041483  511 AIERATTLRRQAEETLERTRAEAERLRA---EAEEQAEEVRAAAERAA------RELREETERAIAARQ---AEAAEELT 578

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  897 RLQSELRQRenehQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE 976
Cdd:NF041483  579 RLHTEAEER----LTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAERLRTEAAADASAARAEGE 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  977 NA---IRQHYRAERDRQLDELV-----VRMEADALQHK--EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGK-- 1044
Cdd:NF041483  655 NVavrLRSEAAAEAERLKSEAQesadrVRAEAAAAAERvgTEAAEALAAAQEEAARRRREAEETLGSARAEADQERERar 734

                         330       340
                  ....*....|....*....|....
gi 386767627 1045 ------LAEADAQVRNSQAEVKQL 1062
Cdd:NF041483  735 eqseelLASARKRVEEAQAEAQRL 758

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

944-1124

9.68e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 43.67 E-value: 9.68e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  944 NRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA--IRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNrlkEKYE 1021
Cdd:NF012221 1533 NVVATSESSQQADAVSKHAKQDDAAQNALADKERAeaDRQRLEQEKQQQLAA--ISGSQSQLESTDQNALETN---GQAQ 1607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1022 KDLVLAES--VEKSLREK---------YAETRGklaEADAQVRNSQAE--VKQLQLELSHSKKMCGDIIME-RDRLRDNL 1087
Cdd:NF012221 1608 RDAILEESraVTKELTTLaqgldaldsQATYAG---ESGDQWRNPFAGglLDRVQEQLDDAKKISGKQLADaKQRHVDNQ 1684

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767627 1088 ----NADIQSELGVLN-ERHKQEMDQ-LQKRVHQTIQRQEETI 1124
Cdd:NF012221 1685 qkvkDAVAKSEAGVAQgEQNQANAEQdIDDAKADAEKRKDDAL 1727

PRK11281

mechanosensitive channel MscK;

996-1150

6.68e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 6.68e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  996 VRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLqlelshsKKMCGD 1075
Cdd:PRK11281   41 VQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQ-KEETEQLKQQLAQAPAKLRQAQAELEAL-------KDDNDE 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1076 IIMER------DRLRDNLN------ADIQSELGVLN----------ERHKQEMDQLQKRVhQTIQRQEETIEILKGDNDA 1133
Cdd:PRK11281  113 ETRETlstlslRQLESRLAqtldqlQNAQNDLAEYNsqlvslqtqpERAQAALYANSQRL-QQIRNLLKGGKVGGKALRP 191

                         170       180
                  ....*....|....*....|..
gi 386767627 1134 LRQQCLK-----LNAVIRQQRK 1150
Cdd:PRK11281  192 SQRVLLQaeqalLNAQNDLQRK 213

OmpH

smart00935

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

880-955

7.85e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.

Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 37.95 E-value: 7.85e-03

                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627    880 QAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQA 955
Cdd:smart00935   12 ESPAGKAAQKQLEKEFKKRQAELEKLEKELQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQK 87

Name

Accession

Description

Interval

E-value

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

827-1066

7.15e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.51 E-value: 7.15e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  827 QLLDALEEARTKHEQIETSIRESCAQDRE-AIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDR-LQSELRQ 904
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAElAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIaRLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  905 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHYR 984
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAE-----AEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  985 AERDRQLDELVvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQL 1064
Cdd:COG1196   387 ELLEALRAAAE---LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463


                  ..
gi 386767627 1065 EL 1066
Cdd:COG1196   464 LL 465

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

698-1030

8.40e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 76.13 E-value: 8.40e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  698 EKQ-KSLRAEKSTA--AAKLRDQKKHYEEVVTRHQgfIEQLLKDKGSLCEKVAALTRRLESQnQAWEHRLETELARTKEt 774
Cdd:COG1196   199 ERQlEPLERQAEKAerYRELKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEEL-EAELAELEAELEELRL- 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  775 tmageKIRRERwvrentKKIKELtvKGLEAEINKmncdhQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDR 854
Cdd:COG1196   275 -----ELEELE------LELEEA--QAEEYELLA-----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  855 EAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQER 934
Cdd:COG1196   337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL-RAAAELAAQLEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  935 MAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRmEADALQHKEEHELKMN 1014
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLL 494

                         330
                  ....*....|....*.
gi 386767627 1015 RLKEKYEKDLVLAESV 1030
Cdd:COG1196   495 LLLEAEADYEGFLEGV 510

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

783-1151

8.80e-14

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 76.25 E-value: 8.80e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   783 RERWVRENTKKIKELTVKGLEAEInkmncdhqrEVTELKRTHQmQLLDALEEARTKHEQIETSIREscAQDREAIIEKER 862
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEK---------ALAELRKELE-ELEEELEQLRKELEELSRQISA--LRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   863 TAIRERFERQ------LEEEQRTQAEQRQKLTEEFAA---ERDRLQSELRQRENEHQArrqeaLREQEQELEQAKFEMQE 933
Cdd:TIGR02168  743 EQLEERIAQLskelteLEAEIEELEERLEEAEEELAEaeaEIEELEAQIEQLKEELKA-----LREALDELRAELTLLNE 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   934 RMAKQEEKYQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVrmeadALQHKEEHELKM 1013
Cdd:TIGR02168  818 EAANLRERLESLERRIAATER---RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA-----LLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1014 NRLKEKYEK---DLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1090
Cdd:TIGR02168  890 ALLRSELEElseELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767627  1091 IQ----------SELGVLNERHKQEMDQLQKRvHQTIQRQEETIEILKGDndaLRQQCLKLNAVIRQQRKD 1151
Cdd:TIGR02168  970 ARrrlkrlenkiKELGPVNLAAIEEYEELKER-YDFLTAQKEDLTEAKET---LEEAIEEIDREARERFKD 1036

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

694-1068

1.29e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 1.29e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  694 QLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKE 773
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  774 -TTMAGEKIRRERWVRENTKKIKELTVKGLEAEinkmncDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREScAQ 852
Cdd:COG1196   297 lARLEQDIARLEERRRELEERLEELEEELAELE------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL-LE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  853 DREAIIEKERTaiRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENehQARRQEALREQEQELEQAKFEMQ 932
Cdd:COG1196   370 AEAELAEAEEE--LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE--LEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  933 ERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKenairqhyRAERDRQLDELVVRMEADALQHKEEHELK 1012
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--------AAARLLLLLEAEADYEGFLEGVKAALLLA 517

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627 1013 MNRLKEKYEKDLVLAESVEkslrEKYAETRGKLAEADAQVRNSQAEVKQLQLELSH 1068
Cdd:COG1196   518 GLRGLAGAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

818-1149

2.96e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 2.96e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  818 TELKRTHQMQLLDALEEARTKHEQIETSIREscaqdreaiiekeRTAIRERFERQLEEEQRTQAEQRQKLTEEfAAERDR 897
Cdd:COG1196   220 EELKELEAELLLLKLRELEAELEELEAELEE-------------LEAELEELEAELAELEAELEELRLELEEL-ELELEE 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  898 LQSELRQRENEHQA--RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEK 975
Cdd:COG1196   286 AQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  976 ENAIRQHYRAERDRQLDELVVRmEADALQHKEEHELKMNRLKEkyekdlvlAESVEKSLREKYAETRGKLAEADAQVRNS 1055
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEE-LLEALRAAAELAAQLEELEE--------AEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1056 QAEVKQLQLELSHSKKmcgdiimERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRvhQTIQRQEETIEILKGDNDALR 1135
Cdd:COG1196   437 EEEEEEALEEAAEEEA-------ELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFL 507

                         330
                  ....*....|....
gi 386767627 1136 QQCLKLNAVIRQQR 1149
Cdd:COG1196   508 EGVKAALLLAGLRG 521

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

754-1050

3.20e-11

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 67.84 E-value: 3.20e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   754 ESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKG-LEAEINKMNCDHQREVT---------ELKRT 823
Cdd:pfam17380  286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAaIYAEQERMAMERERELErirqeerkrELERI 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   824 HQMQL------LDALEEARTKHEQIETSIRESC-AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERD 896
Cdd:pfam17380  366 RQEEIameisrMRELERLQMERQQKNERVRQELeAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   897 RLQSELRQRENEHQaRRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwKTEHENKTKLAQAEKE 976
Cdd:pfam17380  446 REMERVRLEEQERQ-QQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQA-MIEEERKRKLLEKEME 523

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767627   977 NAIRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEADA 1050
Cdd:pfam17380  524 ERQKAIYEEERRREAEE--ERRKQQEMEERRRIQEQMRKATE--ERSRLEAMEREREMMRQIVESEKARAEYEA 593

PTZ00121

MAEBL; Provisional

698-1072

1.07e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 66.32 E-value: 1.07e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  698 EKQKSLRAEKSTAAAKLR-DQKKHYEEVVTRHQGFIEQLLKDKGSLCEKvAALTRRLESQNQAWEHRLETELARTKETTM 776
Cdd:PTZ00121 1481 EAKKADEAKKKAEEAKKKaDEAKKAAEAKKKADEAKKAEEAKKADEAKK-AEEAKKADEAKKAEEKKKADELKKAEELKK 1559

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  777 AGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSirescaqdrea 856
Cdd:PTZ00121 1560 AEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA----------- 1628

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  857 iiEKERTAIRERfeRQLEEEQRTQAEQRQKlteefAAERDRLQSELRQRENEHQARRQEALREQEQElEQAKFEMQERMA 936
Cdd:PTZ00121 1629 --EEEKKKVEQL--KKKEAEEKKKAEELKK-----AEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEA 1698

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  937 KQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnAIRQHYRAERDRQLDElvvrmEADALQHKEEHELKMNRL 1016
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE-AEEDKKKAEEAKKDEE-----EKKKIAHLKKEEEKKAEE 1772

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627 1017 KEKyEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKM 1072
Cdd:PTZ00121 1773 IRK-EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM 1827

PTZ00121

MAEBL; Provisional

677-1111

2.13e-10

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.55 E-value: 2.13e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  677 RANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEV--VTRHQGFIEQLLKDKGSLCEKVAALTRRLE 754
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKkkADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  755 SQNQAWEHRLETELARTKETTMAGEKIRRERwvrENTKKIKELTVKGLE---AEINKMNCDHQREVTELKRTHQMQLLDA 831
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKA---EEAKKAEEAKKKAEEakkADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  832 lEEARTKHEQIETSIRESCAQD-REAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQ 910
Cdd:PTZ00121 1500 -DEAKKAAEAKKKADEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNM 1578

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  911 A-RRQEALREQEQ-------ELEQAKFEMQERMAKQEEKYQNRVNTI---EQQYQADFELWKTEHENKTK---LAQAEKE 976
Cdd:PTZ00121 1579 AlRKAEEAKKAEEarieevmKLYEEEKKMKAEEAKKAEEAKIKAEELkkaEEEKKKVEQLKKKEAEEKKKaeeLKKAEEE 1658

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  977 NAIRQHY---RAERDRQLDELVVRME------ADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAE 1047
Cdd:PTZ00121 1659 NKIKAAEeakKAEEDKKKAEEAKKAEedekkaAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE 1738

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 386767627 1048 ADAQVRNSQaEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQLQK 1111
Cdd:PTZ00121 1739 AEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801

mukB

chromosome partition protein MukB;

815-1150

2.13e-10

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 65.36 E-value: 2.13e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  815 REVTELKRTHQmqlldALEEARTKHEQIetsireSCAQDREAIIEKERTAIRERfERQLE--EEQRTQAEQRQKLTEEFA 892
Cdd:PRK04863  807 FDVQKLQRLHQ-----AFSRFIGSHLAV------AFEADPEAELRQLNRRRVEL-ERALAdhESQEQQQRSQLEQAKEGL 874

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  893 AERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQermakqeeKYQNRVNTIEQQY------QADFELWKTEHEn 966
Cdd:PRK04863  875 SALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRFVQ--------QHGNALAQLEPIVsvlqsdPEQFEQLKQDYQ- 945

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  967 ktklaQAEKenaiRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKyekdlvlaesveksLREKYAETRGKLA 1046
Cdd:PRK04863  946 -----QAQQ----TQRDAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEK--------------LRQRLEQAEQERT 1002

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1047 EADAQVRNSQAEVKQlqlelshSKKMCGDIIMERDRLRDNLNADIQ--SELGV-----LNERHKQEMDQLQKRVHQTIQR 1119
Cdd:PRK04863 1003 RAREQLRQAQAQLAQ-------YNQVLASLKSSYDAKRQMLQELKQelQDLGVpadsgAEERARARRDELHARLSANRSR 1075

                         330       340       350
                  ....*....|....*....|....*....|....
gi 386767627 1120 Q---EETIEILKGDNDALRQQCLKLNAVIRQQRK 1150
Cdd:PRK04863 1076 RnqlEKQLTFCEAEMDNLTKKLRKLERDYHEMRE 1109

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

852-1134

9.68e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.16 E-value: 9.68e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   852 QDREAIIEKERTAIRERFER--QLEEEQRTQAEQRQKLTEEFAAERDRLQSElRQRENEHQARRQEALREQEQELEQAKF 929
Cdd:TIGR02169  680 RERLEGLKRELSSLQSELRRieNRLDELSQELSDASRKIGEIEKEIEQLEQE-EEKLKERLEELEEDLSSLEQEIENVKS 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   930 EMQE---RMAKQEE---KYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDElvvRMEADAL 1003
Cdd:TIGR02169  759 ELKEleaRIEELEEdlhKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK---EYLEKEI 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1004 QHKEEhelKMNRLKEKyekdlvlaesvEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKmcgdiimERDRL 1083
Cdd:TIGR02169  836 QELQE---QRIDLKEQ-----------IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK-------ERDEL 894

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 386767627  1084 rdnlnadiQSELGVLNERHKQEMDQLQKRVHQtIQRQEETIEILKGDNDAL 1134
Cdd:TIGR02169  895 --------EAQLRELERKIEELEAQIEKKRKR-LSELKAKLEALEEELSEI 936

PTZ00121

MAEBL; Provisional

688-1047

1.22e-09

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.85 E-value: 1.22e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  688 SKEHVFQLRGEKQKSL-----RAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLceKVAALTRRLESQNQAWEH 762
Cdd:PTZ00121 1062 AKAHVGQDEGLKPSYKdfdfdAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAK--KKAEDARKAEEARKAEDA 1139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  763 R-----------------------LETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTE 819
Cdd:PTZ00121 1140 RkaeearkaedakrveiarkaedaRKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARK 1219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  820 LKRTHQMQLLDALEEARTKHEqietsirESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQ 899
Cdd:PTZ00121 1220 AEDAKKAEAVKKAEEAKKDAE-------EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  900 SELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNrvntIEQQYQADfELWKTEHENKTKLAQAEKENAI 979
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAA-EAAKAEAEAAADEAEAAEEKAE 1367

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767627  980 RQHYRAERDRQldelvvrmEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLRE-KYAETRGKLAE 1047
Cdd:PTZ00121 1368 AAEKKKEEAKK--------KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAkKKADEAKKKAE 1428

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

783-1061

1.84e-09

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 60.70 E-value: 1.84e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   783 RERWVRENtKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETsiRESCAQDREAIIEKER 862
Cdd:pfam13868   24 RDAQIAEK-KRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQIEE--REQKRQEEYEEKLQER 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   863 TAIRERFERQLEEEQRTQAEQRQKLTE------EFAAERDRLQSELRQRENE----------HQARRQEALREQEQELEQ 926
Cdd:pfam13868  101 EQMDEIVERIQEEDQAEAEEKLEKQRQlreeidEFNEEQAEWKELEKEEEREederileylkEKAEREEEREAEREEIEE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   927 AKFEMQERMAKQEEKYQNRvntIEQQYQADFELWKTEHENKTK---LAQAEKENAIRQHYRAERDRQLDELVVRMEADAL 1003
Cdd:pfam13868  181 EKEREIARLRAQQEKAQDE---KAERDELRAKLYQEEQERKERqkeREEAEKKARQRQELQQAREEQIELKERRLAEEAE 257

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627  1004 QHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQ 1061
Cdd:pfam13868  258 REEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELE 315

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

712-1118

5.54e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.17 E-value: 5.54e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  712 AKLRDQKKHYEEVVTRHQGfIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKettmAGEKIRRERWVRENT 791
Cdd:COG4717    81 KEAEEKEEEYAELQEELEE-LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAE----LAELPERLEELEERL 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  792 KKIKEL--TVKGLEAEINKmncdHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREscAQDREAIIEKERTAIRERF 869
Cdd:COG4717   156 EELRELeeELEELEAELAE----LQEELEELLEQLSLATEEELQDLAEELEELQQRLAE--LEEELEEAQEELEELEEEL 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  870 ErQLEEEQRTQAEQRQKLTEE-----------FAAERDRLQSELRQREN-------------EHQARRQEALREQEQELE 925
Cdd:COG4717   230 E-QLENELEAAALEERLKEARlllliaaallaLLGLGGSLLSLILTIAGvlflvlgllallfLLLAREKASLGKEAEELQ 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  926 QAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEN--AIRQHYRAERDRQLDELVVRMEAD-- 1001
Cdd:COG4717   309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeeLQLEELEQEIAALLAEAGVEDEEElr 388

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1002 --ALQHKEEHELK--MNRLKEKYEKDL-----VLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHskkm 1072
Cdd:COG4717   389 aaLEQAEEYQELKeeLEELEEQLEELLgeleeLLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ---- 464

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 386767627 1073 cgdiiMERDRLRDNLNADIQSELGVLNERHKQE---------MDQLQKRVHQTIQ 1118
Cdd:COG4717   465 -----LEEDGELAELLQELEELKAELRELAEEWaalklalelLEEAREEYREERL 514

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

853-1150

6.67e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 60.35 E-value: 6.67e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  853 DREAIIEKERTAIRErFERQLEEEQRTQAEQRQKLTEefAAER----DRLQSELRQRENEHQARRQEALREQEQELEQAK 928
Cdd:COG3096   833 DPEAELAALRQRRSE-LERELAQHRAQEQQLRQQLDQ--LKEQlqllNKLLPQANLLADETLADRLEELREELDAAQEAQ 909

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  929 FEMQeRMAKQEEKYQNRVNTIeQQYQADFELWKTEHENktklAQAEKENAIRQHYraerdrQLDELVVRMEADALQHKEE 1008
Cdd:COG3096   910 AFIQ-QHGKALAQLEPLVAVL-QSDPEQFEQLQADYLQ----AKEQQRRLKQQIF------ALSEVVQRRPHFSYEDAVG 977

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1009 HELKMNRLKEKYEKDLVLAESvekslrekyaetrgKLAEADAQVRNSQAEVKQLQLELSHSKKmcgdiimERDRLRDNLN 1088
Cdd:COG3096   978 LLGENSDLNEKLRARLEQAEE--------------ARREAREQLRQAQAQYSQYNQVLASLKS-------SRDAKQQTLQ 1036

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767627 1089 ADIQ--SELGVLN-----ERHKQEMDQLQKRVHQTIQRQ---EETIEILKGDNDALRQQCLKLNAVIRQQRK 1150
Cdd:COG3096  1037 ELEQelEELGVQAdaeaeERARIRRDELHEELSQNRSRRsqlEKQLTRCEAEMDSLQKRLRKAERDYKQERE 1108

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

864-1066

1.56e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.01 E-value: 1.56e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  864 AIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHqarrqEALREQEQELEQAKfEMQERMAKQEEKYQ 943
Cdd:COG4717    42 FIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKE-----EEYAELQEELEELE-EELEELEAELEELR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  944 NRVNTIEQQYQAdFELWKTEHENKTKLAQAEKE-NAIRQHY--RAERDRQLDELvvrmEADALQHKEEHELKMNRLKEKY 1020
Cdd:COG4717   116 EELEKLEKLLQL-LPLYQELEALEAELAELPERlEELEERLeeLRELEEELEEL----EAELAELQEELEELLEQLSLAT 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 386767627 1021 EKDLvlaesveKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLEL 1066
Cdd:COG4717   191 EEEL-------QDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

844-1150

1.75e-08

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.93 E-value: 1.75e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   844 TSIRESCAQDREAIIEkeRTAIRERFERQLEEEQRTQAEQRQKLteefaAERDRLQSELRQRENEHQARRQEALREQEQE 923
Cdd:TIGR02169  145 TDFISMSPVERRKIID--EIAGVAEFDRKKEKALEELEEVEENI-----ERLDLIIDEKRQQLERLRREREKAERYQALL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   924 LEQAKFEMQER------MAKQEEKYQNRVNTIEQQyQADF-----ELWKTEHENKTKLAQAEKE---------NAIR--- 980
Cdd:TIGR02169  218 KEKREYEGYELlkekeaLERQKEAIERQLASLEEE-LEKLteeisELEKRLEEIEQLLEELNKKikdlgeeeqLRVKeki 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   981 ---QHYRAERDRQLDELVVRME-ADALQHKEEHEL-----KMNRLKEKYEKDLVLAESVE---KSLREKYAETRGKLAEA 1048
Cdd:TIGR02169  297 gelEAEIASLERSIAEKERELEdAEERLAKLEAEIdkllaEIEELEREIEEERKRRDKLTeeyAELKEELEDLRAELEEV 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1049 DAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLN------ADIQSELGVLNERHKQ---EMDQLQKRVHQTIQR 1119
Cdd:TIGR02169  377 DKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQrlseelADLNAAIAGIEAKINEleeEKEDKALEIKKQEWK 456

                          330       340       350
                   ....*....|....*....|....*....|.
gi 386767627  1120 QEETIEILKGDNDALRQQCLKLNAVIRQQRK 1150
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSK 487

DUF5401

pfam17380

Family of unknown function (DUF5401); This is a family of unknown function found in ...

827-1136

2.47e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.

Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 58.21 E-value: 2.47e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   827 QLLDALEEARTKHEQIETSIRESCAQDREAIiEKERTAIRERFERQLEE-EQRTQAE---------QRQKLTEEFAAERD 896
Cdd:pfam17380  273 QLLHIVQHQKAVSERQQQEKFEKMEQERLRQ-EKEEKAREVERRRKLEEaEKARQAEmdrqaaiyaEQERMAMERERELE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   897 RLQSELRQRENEhQARRQEALREQEQ--ELEQAKFEMQER--MAKQEEKYQNRVNTIEQQYQADFELWKTEHENktklAQ 972
Cdd:pfam17380  352 RIRQEERKRELE-RIRQEEIAMEISRmrELERLQMERQQKneRVRQELEAARKVKILEEERQRKIQQQKVEMEQ----IR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   973 AEKENAIRQHYR---AERDRQLDElvVRMEadalQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEAD 1049
Cdd:pfam17380  427 AEQEEARQREVRrleEERAREMER--VRLE----EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1050 AQVRnsqaevKQLQLELSHSKKMCGDIIMErdrlRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEET---IEI 1126
Cdd:pfam17380  501 LEER------KQAMIEEERKRKLLEKEMEE----RQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEErsrLEA 570

                          330
                   ....*....|
gi 386767627  1127 LKGDNDALRQ 1136
Cdd:pfam17380  571 MEREREMMRQ 580

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

851-1151

2.97e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.02 E-value: 2.97e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  851 AQDREAIIE--------KERtaiRERFERQLEEeqrtqAEQR----QKLTEEFAAERDRLQselRQREnehQARRQEALR 918
Cdd:COG1196   154 PEERRAIIEeaagiskyKER---KEEAERKLEA-----TEENlerlEDILGELERQLEPLE---RQAE---KAERYRELK 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  919 EqeqELEQAKFEM--------QERMAKQEEKYQNRVNTIEQQyQADFELWKTEHEnKTKLAQAEKENAIRQhyRAERDRQ 990
Cdd:COG1196   220 E---ELKELEAELlllklrelEAELEELEAELEELEAELEEL-EAELAELEAELE-ELRLELEELELELEE--AQAEEYE 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  991 LDELVVRMEADaLQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSK 1070
Cdd:COG1196   293 LLAELARLEQD-IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1071 KMCGDIIMERDRLRDNLNADIQSELGVLNERhkQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRK 1150
Cdd:COG1196   372 AELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449


                  .
gi 386767627 1151 D 1151
Cdd:COG1196   450 E 450

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

673-1009

3.01e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 58.43 E-value: 3.01e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  673 ALSLRANELANAIHMSKEHvfQLRGEKQKSLRAEKSTAAAklrdqkkHYEEVVT--RHQGFIEQLLKDkgslcekVAALT 750
Cdd:COG3096   297 ARRQLAEEQYRLVEMAREL--EELSARESDLEQDYQAASD-------HLNLVQTalRQQEKIERYQED-------LEELT 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  751 RRLESQNQAWEHRLEtELARTKETTMAGEKirrerwvrentkkikelTVKGLEAEInkmnCDHQREVTELK-RTHQ-MQL 828
Cdd:COG3096   361 ERLEEQEEVVEEAAE-QLAEAEARLEAAEE-----------------EVDSLKSQL----ADYQQALDVQQtRAIQyQQA 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  829 LDALEEARTKHEQIETSIrESCAQDREAIIEKERTAIRERFE-RQ---LEEEQRTQAEQRQKLTEEFAAERDRLQSELRQ 904
Cdd:COG3096   419 VQALEKARALCGLPDLTP-ENAEDYLAAFRAKEQQATEEVLElEQklsVADAARRQFEKAYELVCKIAGEVERSQAWQTA 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  905 RENEHQARRQEALREQEQELEQAKFEMQERMAKQE--EKYQNRVN-TIEQQYQA--DFELWKTEHENKTKLAQAEKENAI 979
Cdd:COG3096   498 RELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQnaERLLEEFCqRIGQQLDAaeELEELLAELEAQLEELEEQAAEAV 577

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 386767627  980 RQhyRAERDRQLDELVVRME------------ADALQHKEEH 1009
Cdd:COG3096   578 EQ--RSELRQQLEQLRARIKelaarapawlaaQDALERLREQ 617

PTZ00121

MAEBL; Provisional

698-1122

1.56e-07

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.92 E-value: 1.56e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  698 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTrhqgfIEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMA 777
Cdd:PTZ00121 1288 EKKKADEAKKAEEKKKADEAKKKAEEAKK-----ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  778 GEKIRRERWVRENTKKikeltvkglEAEINKMNCDHQREVTELKRThqmqlldaLEEARTKHEQIETSIRESCAQDrEAI 857
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKK---------KADAAKKKAEEKKKADEAKKK--------AEEDKKKADELKKAAAAKKKAD-EAK 1424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  858 IEKERTAIRERFERQLEEEQRTQaEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQE--QELEQAKFEMQE-R 934
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKAEEAKKAD-EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEakKKAEEAKKKADEaK 1503

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  935 MAKQEEKYQNRVNTIEQQYQADfELWKTEHENKtklaqAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMN 1014
Cdd:PTZ00121 1504 KAAEAKKKADEAKKAEEAKKAD-EAKKAEEAKK-----ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKN 1577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1015 RLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSE 1094
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657

                         410       420
                  ....*....|....*....|....*...
gi 386767627 1095 LGVLNERHKQEMDQLQKRVHQTIQRQEE 1122
Cdd:PTZ00121 1658 ENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

698-955

1.58e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.83 E-value: 1.58e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   698 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRhQGFIEQLLKDKGSLCEKVAALTRRLESQNQAwEHRLETELARTKEttma 777
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQEL-EEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRE---- 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   778 gekiRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIREscaqdREAI 857
Cdd:TIGR02168  310 ----RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE-----LEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   858 IEKERTAIRERfERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQ---ER 934
Cdd:TIGR02168  381 LETLRSKVAQL-ELQIASLNNEIERLEARL-ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQeelER 458

                          250       260
                   ....*....|....*....|.
gi 386767627   935 MAKQEEKYQNRVNTIEQQYQA 955
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDA 479

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

710-1151

2.93e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.92 E-value: 2.93e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  710 AAAKLRDQKKHYEEVVTRHQGFIEQLLKdkgslcekvAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRE 789
Cdd:COG4913   243 ALEDAREQIELLEPIRELAERYAAARER---------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  790 NTKKIKELTVKGLEAEINKMNCDHQReVTELKRthqmqLLDALEEARTKHEQIETSIRESCAQdreaiIEKERTAIRERF 869
Cdd:COG4913   314 LEARLDALREELDELEAQIRGNGGDR-LEQLER-----EIERLERELEERERRRARLEALLAA-----LGLPLPASAEEF 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  870 ERQLEEEQRtQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQE--ALREQ----EQELEQAKFEMQER--------- 934
Cdd:COG4913   383 AALRAEAAA-LLEALEEELEALEEALAEAEAALRDLRRELRELEAEiaSLERRksniPARLLALRDALAEAlgldeaelp 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  935 -------MAKQEEKYQNRVNT----------IEQQYQADFelwkTEHENKTKLAQaekenaiRQHYRAERDRQLDELVVR 997
Cdd:COG4913   462 fvgelieVRPEEERWRGAIERvlggfaltllVPPEHYAAA----LRWVNRLHLRG-------RLVYERVRTGLPDPERPR 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  998 MEADALQHK---EEHELKmNRLKEKYEK--DLVLAESVEKSLREKYAETR-------GKLAEADAQVRNS---------- 1055
Cdd:COG4913   531 LDPDSLAGKldfKPHPFR-AWLEAELGRrfDYVCVDSPEELRRHPRAITRagqvkgnGTRHEKDDRRRIRsryvlgfdnr 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1056 ------QAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAdiqseLGVLNERHKQEMDQLQkrVHQTIQRQEETIEILKG 1129
Cdd:COG4913   610 aklaalEAELAELEEELAEAEERLEALEAELDALQERREA-----LQRLAEYSWDEIDVAS--AEREIAELEAELERLDA 682

                         490       500
                  ....*....|....*....|....*
gi 386767627 1130 DND---ALRQQCLKLNAVIRQQRKD 1151
Cdd:COG4913   683 SSDdlaALEEQLEELEAELEELEEE 707

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

744-1071

3.23e-07

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.69 E-value: 3.23e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   744 EKVAALTRRLEsQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKEL--TVKGLEAEINKMNcdhqREVTELK 821
Cdd:TIGR02169  211 ERYQALLKEKR-EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELekRLEEIEQLLEELN----KKIKDLG 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   822 RTHQMQLLDALEEARTKHEQIETSIRESC-----AQDREAIIEKERTAIRERFErQLEEEQRTQAeqrqklteefaAERD 896
Cdd:TIGR02169  286 EEEQLRVKEKIGELEAEIASLERSIAEKEreledAEERLAKLEAEIDKLLAEIE-ELEREIEEER-----------KRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   897 RLQSELRQRENEHQARRQEAlreqeqeleqakfemqermakqeekyqnrvntieQQYQADFELWKTEHenktKLAQAEKE 976
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAEL----------------------------------EEVDKEFAETRDEL----KDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   977 NAIRQHY--RAERDRQLDELvVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRN 1054
Cdd:TIGR02169  396 KLKREINelKRELDRLQEEL-QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ-EWKLEQLAADLSKYEQELYD 473

                          330
                   ....*....|....*..
gi 386767627  1055 SQAEVKQLQLELSHSKK 1071
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQR 490

mukB

chromosome partition protein MukB;

673-1019

3.43e-07

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 54.96 E-value: 3.43e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  673 ALSLRAnELANA---IHMSKEHVFQLRGEKQKSLRAEKSTAAAkLRDQKKHYEEVVT--RHQGFIEQLLKDkgslcekVA 747
Cdd:PRK04863  288 ALELRR-ELYTSrrqLAAEQYRLVEMARELAELNEAESDLEQD-YQAASDHLNLVQTalRQQEKIERYQAD-------LE 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  748 ALTRRLESQNQAWEHRLETELARTKETTMAGEKIRR---------ERWVRENTKKIK------------------ELTVK 800
Cdd:PRK04863  359 ELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDElksqladyqQALDVQQTRAIQyqqavqalerakqlcglpDLTAD 438

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  801 GLEAEINKMNcDHQREVTElKRTHQMQLLDALEEARTKHEQIETSI----------------RESCAQDREAIIEKERT- 863
Cdd:PRK04863  439 NAEDWLEEFQ-AKEQEATE-ELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsrseawdvaRELLRRLREQRHLAEQLq 516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  864 AIRERF---ERQLEEEQR-----TQAEQRQKLTEEFAAERDRLQSELRQRENEHQArRQEALREQ----EQELEQAKFEM 931
Cdd:PRK04863  517 QLRMRLselEQRLRQQQRaerllAEFCKRLGKNLDDEDELEQLQEELEARLESLSE-SVSEARERrmalRQQLEQLQARI 595

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  932 QERMAKQEE--KYQNRVNTIEQQYQADFElwKTEHENKTKLAQAEKENAIRQHYR--AERDRQLDElvvrmEADALQHKE 1007
Cdd:PRK04863  596 QRLAARAPAwlAAQDALARLREQSGEEFE--DSQDVTEYMQQLLERERELTVERDelAARKQALDE-----EIERLSQPG 668

                         410
                  ....*....|...
gi 386767627 1008 EHEL-KMNRLKEK 1019
Cdd:PRK04863  669 GSEDpRLNALAER 681

PRK12704

phosphodiesterase; Provisional

820-944

5.69e-07

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 53.63 E-value: 5.69e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  820 LKRTHQMQLLDALEEARtkhEQIETSIRESCAQDREAIIE--KERTAIRERFERQLEEEQR--TQAEQRQKLTEEFAaer 895
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAK---RILEEAKKEAEAIKKEALLEakEEIHKLRNEFEKELRERRNelQKLEKRLLQKEENL--- 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 386767627  896 DRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEEKYQN 944
Cdd:PRK12704   99 DRKLELLEKREEELEKKEKE-LEQKQQELEKKEEELEELIEEQLQELER 146

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

744-994

6.34e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 6.34e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  744 EKVAALTRRLESQNQAWEhRLETELARTKETTMAGEKIRRERWVrentkkikELTVKGLEAEINkmncDHQREVTELKRT 823
Cdd:COG4913   617 AELAELEEELAEAEERLE-ALEAELDALQERREALQRLAEYSWD--------EIDVASAEREIA----ELEAELERLDAS 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  824 HQMqlLDALEE----ARTKHEQIETSIREscAQDREAIIEKERTAIRERFER---QLEE-EQRTQAEQRQKLTEEFAAE- 894
Cdd:COG4913   684 SDD--LAALEEqleeLEAELEELEEELDE--LKGEIGRLEKELEQAEEELDElqdRLEAaEDLARLELRALLEERFAAAl 759

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  895 RDRLQSELRQRENEHQARRQEALREQEQELEQA--------KFEMQERMAKQE--EKYQNRVNTIEQ----QYQADFElw 960
Cdd:COG4913   760 GDAVERELRENLEERIDALRARLNRAEEELERAmrafnrewPAETADLDADLEslPEYLALLDRLEEdglpEYEERFK-- 837

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 386767627  961 ktehENKTKLAQAEKENAIRQHYRAERD--RQLDEL 994
Cdd:COG4913   838 ----ELLNENSIEFVADLLSKLRRAIREikERIDPL 869

PRK02224

DNA double-strand break repair Rad50 ATPase;

792-1151

6.54e-07

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.89 E-value: 6.54e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  792 KKIKEL--TVKGLEAEINKM-----NCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAiiEKERTA 864
Cdd:PRK02224  199 KEEKDLheRLNGLESELAELdeeieRYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAET--EREREE 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  865 IRERFerqleeeqRTQAEQRQKLTEEFAAERDRlqSELRQRENEHQARRQEALREQEQELEQAKfeMQERMAKQE----- 939
Cdd:PRK02224  277 LAEEV--------RDLRERLEELEEERDDLLAE--AGLDDADAEAVEARREELEDRDEELRDRL--EECRVAAQAhneea 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  940 EKYQNRVNTIEQQYQadfELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEaDAlqhkeehelkmnrlkek 1019
Cdd:PRK02224  345 ESLREDADDLEERAE---ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG-DA----------------- 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1020 yEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSK-KMCG---------DIIMERDRLRDNLNA 1089
Cdd:PRK02224  404 -PVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcPECGqpvegsphvETIEEDRERVEELEA 482

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627 1090 ---DIQSELGVLNERHKQ---------EMDQLQ---KRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRKD 1151
Cdd:PRK02224  483 eleDLEEEVEEVEERLERaedlveaedRIERLEerrEDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA 559

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

814-1143

6.71e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.91 E-value: 6.71e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   814 QREVTELK----RTHQMQLLDALEEARTKHEQIEtsIRESCAQD----REAIIEKERTAIRERFErQLEEEQRTQAEQRQ 885
Cdd:TIGR02168  173 RRKETERKlertRENLDRLEDILNELERQLKSLE--RQAEKAERykelKAELRELELALLVLRLE-ELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   886 KLTEEFAAERDRLQ-------------SELRQRENEHQARRQEALREQEqELEQAKFEMQERMAKQEEKYQNRVNTIEQQ 952
Cdd:TIGR02168  250 EAEEELEELTAELQeleekleelrlevSELEEEIEELQKELYALANEIS-RLEQQKQILRERLANLERQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   953 YQADFELWKTEHENKTKLAQAEKEnairqhyraerdrqldelvvrMEADALQHKEEHELKMNrLKEKYEKDLVLAEsvek 1032
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEE---------------------LESLEAELEELEAELEE-LESRLEELEEQLE---- 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1033 SLREKYAETRGKLAEADAQVRNSQAEVKQLQLELshsKKMCGDIIMERDRLRDNLNADIQSELgvlnERHKQEMDQLQKR 1112
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRR---ERLQQEIEELLKKLEEAELKELQAEL----EELEEELEELQEE 455

                          330       340       350
                   ....*....|....*....|....*....|....
gi 386767627  1113 VHQTIQR---QEETIEILKGDNDALRQQCLKLNA 1143
Cdd:TIGR02168  456 LERLEEAleeLREELEEAEQALDAAERELAQLQA 489

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

814-994

8.46e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 8.46e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  814 QREVTELKRTHQmQLLDA------LEEARTKHEQIETSIREscAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKL 887
Cdd:COG4913   231 VEHFDDLERAHE-ALEDAreqielLEPIRELAERYAAARER--LAELEYLRAALRLWFAQRRLELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  888 TeefaAERDRLQS---ELRQRENEHQARRQEA----LREQEQELEQAKFEMQERmAKQEEKYQNRVNTIEQQY---QADF 957
Cdd:COG4913   308 E----AELERLEArldALREELDELEAQIRGNggdrLEQLEREIERLERELEER-ERRRARLEALLAALGLPLpasAEEF 382

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 386767627  958 -ELWKTEHENKTKLAQAEK--ENAIRQHYRAERD--RQLDEL 994
Cdd:COG4913   383 aALRAEAAALLEALEEELEalEEALAEAEAALRDlrRELREL 424

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

867-1066

1.11e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 52.59 E-value: 1.11e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   867 ERFERQLEEEQRTQAEQRQKLteEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRV 946
Cdd:pfam07888   30 ELLQNRLEECLQERAELLQAQ--EAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELS 107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   947 NTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHElkmnrLKEKYEKDLVL 1026
Cdd:pfam07888  108 ASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEA-----ERKQLQAKLQQ 182

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 386767627  1027 AESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLEL 1066
Cdd:pfam07888  183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKL 222

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

851-1004

1.21e-06

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 52.18 E-value: 1.21e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  851 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQeqelEQAKfe 930
Cdd:COG2268   188 ALGRRKIAEIIRDARIAEAEAERETEIAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAEERREA----ETAR-- 261

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767627  931 mqermAKQEEKYqnRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQ-----HYRAERDRQLDELVVRMEADALQ 1004
Cdd:COG2268   262 -----AEAEAAY--EIAEANAEREVQRQLEIAEREREIELQEKEAEREEAEleadvRKPAEAEKQAAEAEAEAEAEAIR 333

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

662-1133

1.74e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.53 E-value: 1.74e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   662 LPNHQLARRVIALSLRANELANAIHMSKEHVFQLRGEKqKSLRAEKSTAAAKLrdqkkhyEEVVTRHQGFIEQLLKDKGS 741
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLH-FGYKSDETLIASRQ-------EERQETSAELNQLLRTLDDQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   742 LCEKVAALTRRLESQNQAWEHRlETELARTKETTMAGEKIRRERWVRE--------NTKKIKELTVKGLEAEINKMNCDH 813
Cdd:pfam12128  299 WKEKRDELNGELSAADAAVAKD-RSELEALEDQHGAFLDADIETAAADqeqlpswqSELENLEERLKALTGKHQDVTAKY 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   814 QRE--------VTELKRTHQMqlLDALEEARTK--------HEQIETSIRESC-AQDREAIIEKERTAIRERFER----- 871
Cdd:pfam12128  378 NRRrskikeqnNRDIAGIKDK--LAKIREARDRqlavaeddLQALESELREQLeAGKLEFNEEEYRLKSRLGELKlrlnq 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   872 -QLEEEQRTQAEQ--------RQKLTEEFaAERDRLQSELRQreneHQARRQEALREQEQElEQAKFEMQERMAKQEEKY 942
Cdd:pfam12128  456 aTATPELLLQLENfderieraREEQEAAN-AEVERLQSELRQ----ARKRRDQASEALRQA-SRRLEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   943 QNRVNTIEQQYQADFELWKtehENKTKLAQAEKENAIRQHYRAERDRQLDELV---VRMEADALQHKE--EHELKMNRLK 1017
Cdd:pfam12128  530 FPQAGTLLHFLRKEAPDWE---QSIGKVISPELLHRTDLDPEVWDGSVGGELNlygVKLDLKRIDVPEwaASEEELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1018 EKYEKDLVLAESVEKSLREKYAETRGKLAEADAQ-------VRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNAD 1090
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREetfartaLKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 386767627  1091 IQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDA 1133
Cdd:pfam12128  687 LEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA 729

PRK02224

DNA double-strand break repair Rad50 ATPase;

829-1101

1.80e-06

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.35 E-value: 1.80e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  829 LDALEE-------ARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEqrqklTEEFAAERDRLQS- 900
Cdd:PRK02224  161 LGKLEEyrerasdARLGVERVLSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEE-----IERYEEQREQAREt 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  901 --ELRQRENEHQARRQEAlreqeQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELwktEHENKTKLAQAEKENA 978
Cdd:PRK02224  236 rdEADEVLEEHEERREEL-----ETLEAEIEDLRETIAETEREREELAEEVRDLRERLEEL---EEERDDLLAEAGLDDA 307

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  979 ------IRQHYRAERDRQLDELVVRMEADALQHKEEHElkmnRLKEKYEKdlvlAESVEKSLREKYAETRGKLAEADAQV 1052
Cdd:PRK02224  308 daeaveARREELEDRDEELRDRLEECRVAAQAHNEEAE----SLREDADD----LEERAEELREEAAELESELEEAREAV 379

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 386767627 1053 RNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDnLNADIQSELGVLNER 1101
Cdd:PRK02224  380 EDRREEIEELEEEIEELRERFGDAPVDLGNAED-FLEELREERDELRER 427

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

903-1143

3.16e-06

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.60 E-value: 3.16e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   903 RQRENEHQARRQE--ALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIR 980
Cdd:TIGR02168  666 AKTNSSILERRREieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   981 QHYRAERDRQLDELVVRME------ADALQHKEEHELKMNRLKEKYEKDLVLAesveKSLREKYAETRGKLAEADAQVRN 1054
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEeleerlEEAEEELAEAEAEIEELEAQIEQLKEEL----KALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1055 SQAEVKQLQLELSHSKKMCGDIIMERDRLRDNL--NADIQSELGVLNERHKQEMDQLQKRVHQTIQR----------QEE 1122
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIesLAAEIEELEELIEELESELEALLNERASLEEAlallrseleeLSE 901

                          250       260
                   ....*....|....*....|.
gi 386767627  1123 TIEILKGDNDALRQQCLKLNA 1143
Cdd:TIGR02168  902 ELRELESKRSELRRELEELRE 922

PRK12704

phosphodiesterase; Provisional

854-1027

3.74e-06

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.93 E-value: 3.74e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  854 REAIIEKERTAIRERFERQLEEEQR-TQAEQRQKLTE---EFAAERDRLQSELRQRENEHQaRRQEALREQEQELEQakf 929
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRILEEAKKeAEAIKKEALLEakeEIHKLRNEFEKELRERRNELQ-KLEKRLLQKEENLDR--- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  930 eMQERMAKQEEKYQNRVNTIEQQYQaDFELWKTEHENKTKLAQAEKENaIRQHYRAE-RDRQLDELVVRMEADALQH-KE 1007
Cdd:PRK12704  101 -KLELLEKREEELEKKEKELEQKQQ-ELEKKEEELEELIEEQLQELER-ISGLTAEEaKEILLEKVEEEARHEAAVLiKE 177

                         170       180
                  ....*....|....*....|
gi 386767627 1008 EHELKMNRLKEKYEKDLVLA 1027
Cdd:PRK12704  178 IEEEAKEEADKKAKEILAQA 197

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

800-1127

4.06e-06

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.22 E-value: 4.06e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   800 KGLEAEINKMncdhQREVTELKRtHQMQLLDALEEARTKHEQIETSIrESCAQDREAiiEKERTAIRERFERQLEEEQrt 879
Cdd:TIGR02169  684 EGLKRELSSL----QSELRRIEN-RLDELSQELSDASRKIGEIEKEI-EQLEQEEEK--LKERLEELEEDLSSLEQEI-- 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   880 qaeqrqkltEEFAAERDRLQSELRQREnEHQARRQEALREQEQELEQAKF-EMQERMAKQEE---KYQNRVNTIEQQyqa 955
Cdd:TIGR02169  754 ---------ENVKSELKELEARIEELE-EDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEevsRIEARLREIEQK--- 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   956 dfelwktEHENKTKLAQAEKENAIRQHYRAERDRQLDELvvrmeadalqHKEEHELKMNrlKEKYEKDLVLAESVEKSLR 1035
Cdd:TIGR02169  821 -------LNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI----------EKEIENLNGK--KEELEEELEELEAALRDLE 881

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1036 EKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLnADIQSELGVLNERHKQEMDqlQKRVHQ 1115
Cdd:TIGR02169  882 SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL-SEIEDPKGEDEEIPEEELS--LEDVQA 958

                          330
                   ....*....|..
gi 386767627  1116 TIQRQEETIEIL 1127
Cdd:TIGR02169  959 ELQRVEEEIRAL 970

PRK03918

DNA double-strand break repair ATPase Rad50;

732-1067

4.21e-06

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.22 E-value: 4.21e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  732 IEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNc 811
Cdd:PRK03918  340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK- 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  812 dhqREVTELKrthqmqllDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRErferqLEEEQRTQAEQRQKLTEEF 891
Cdd:PRK03918  419 ---KEIKELK--------KAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKR-----IEKELKEIEEKERKLRKEL 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  892 AAERDRLQSELRQRENEHQArrqEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLA 971
Cdd:PRK03918  483 RELEKVLKKESELIKLKELA---EQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  972 QAEKEnairqhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVE---------KSLREKYAETR 1042
Cdd:PRK03918  560 ELEKK-------LDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKelereekelKKLEEELDKAF 632

                         330       340
                  ....*....|....*....|....*
gi 386767627 1043 GKLAEADAQVRNSQAEVKQLQLELS 1067
Cdd:PRK03918  633 EELAETEKRLEELRKELEELEKKYS 657

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

790-1154

4.62e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 4.62e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  790 NTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERF 869
Cdd:COG4717    69 NLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  870 E---------RQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQEE 940
Cdd:COG4717   149 EeleerleelRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE-LQQRLAELEEELEEAQEELEELEE 227

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  941 KYQNRVNTIEQQYQAD-----------------------------------------------FELWKTEHENKTKLAQA 973
Cdd:COG4717   228 ELEQLENELEAAALEErlkearlllliaaallallglggsllsliltiagvlflvlgllallfLLLAREKASLGKEAEEL 307

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  974 EKENAIRQHYRAERDRQLDEL---------VVRMEADALQHKEEHELKMNRLKEKYEKDlVLAESVEKSLREKYAETRGK 1044
Cdd:COG4717   308 QALPALEELEEEELEELLAALglppdlspeELLELLDRIEELQELLREAEELEEELQLE-ELEQEIAALLAEAGVEDEEE 386

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1045 LAEADAQVRnsqaEVKQLQLELSHSKKMCGDIIMERDRLRDNLN-ADIQSELGVLnERHKQEMDQLQKRVHQTIQRQEET 1123
Cdd:COG4717   387 LRAALEQAE----EYQELKEELEELEEQLEELLGELEELLEALDeEELEEELEEL-EEELEELEEELEELREELAELEAE 461

                         410       420       430
                  ....*....|....*....|....*....|...
gi 386767627 1124 IEILKGDN--DALRQQCLKLNAVIRQQRKDYCV 1154
Cdd:COG4717   462 LEQLEEDGelAELLQELEELKAELRELAEEWAA 494

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

698-1108

4.69e-06

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.99 E-value: 4.69e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   698 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLcekvAALTRRLESQNQAWEHRLETELARTKETTma 777
Cdd:pfam12128  478 EEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSAL----DELELQLFPQAGTLLHFLRKEAPDWEQSI-- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   778 GEKIRRERWVREN-------TKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESC 850
Cdd:pfam12128  552 GKVISPELLHRTDldpevwdGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN 631

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   851 AQDREAIIEKERTAI-----RERFeRQLEEEQRTQAEQRQKLTEE---FAAERDR-LQSELRQRENEHQA---------- 911
Cdd:pfam12128  632 GELEKASREETFARTalknaRLDL-RRLFDEKQSEKDKKNKALAErkdSANERLNsLEAQLKQLDKKHQAwleeqkeqkr 710

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   912 ----RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQaEKENAIRQHYRAER 987
Cdd:pfam12128  711 eartEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKR-EIRTLERKIERIAV 789

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   988 DRQ-LDELVVRMEADALQHK--------------EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQV 1052
Cdd:pfam12128  790 RRQeVLRYFDWYQETWLQRRprlatqlsnieraiSELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 386767627  1053 R-----NSQAEVKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSELGVLNERHKQEMDQ 1108
Cdd:pfam12128  870 SklatlKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHSGSGLAE 930

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

818-994

4.70e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 4.70e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  818 TELKRTHQMQLLDALEEARTKHEQIETSIRE----SCAQDREAIIEKERTAIRERFERQLEeeqrtQAEQRQKLTEEFAA 893
Cdd:COG4717   332 PDLSPEELLELLDRIEELQELLREAEELEEElqleELEQEIAALLAEAGVEDEEELRAALE-----QAEEYQELKEELEE 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  894 ERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEqQYQADFELWKTEHEN---KTKL 970
Cdd:COG4717   407 LEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELE-QLEEDGELAELLQELeelKAEL 485

                         170       180       190
                  ....*....|....*....|....*....|..
gi 386767627  971 AQAEKENA--------IRQHYRAERDRQLDEL 994
Cdd:COG4717   486 RELAEEWAalklalelLEEAREEYREERLPPV 517

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

755-954

5.32e-06

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 50.34 E-value: 5.32e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   755 SQNQAWEHRLETElaRTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKmncdHQREVTELKRTHQMQLLDalEE 834
Cdd:pfam15709  329 EQEKASRDRLRAE--RAEMRRLEVERKRREQEEQRRLQQEQLERAEKMREELEL----EQQRRFEEIRLRKQRLEE--ER 400

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   835 ARTKHEQIETSIRESCAQDREAIIEKE--RTAIRERFERQLEEEQRTQAE-QRQKLTEEFAAERDRLQSELRQREnehqa 911
Cdd:pfam15709  401 QRQEEEERKQRLQLQAAQERARQQQEEfrRKLQELQRKKQQEEAERAEAEkQRQKELEMQLAEEQKRLMEMAEEE----- 475

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 386767627   912 rRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQ 954
Cdd:pfam15709  476 -RLEYQRQKQEAEEKARLEAEERRQKEEEAARLALEEAMKQAQ 517

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

700-941

5.48e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 5.48e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  700 QKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhRLETELARTkETTMAGE 779
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA-ALEAELAEL-EKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  780 KIRRERWVRENTKKIKELTVKGLEAEINKMNcdHQREVTELKRThqMQLLDALEEARTkhEQIETsiresCAQDREAIIE 859
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALLL--SPEDFLDAVRR--LQYLKYLAPARR--EQAEE-----LRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  860 KERTAIRERfeRQLEEEQRTQAEQRQKLTEEfAAERDRLQSELRQRENEHQARRQEaLREQEQELEQAKFEMQERMAKQE 939
Cdd:COG4942   165 LRAELEAER--AELEALLAELEEERAALEAL-KAERQKLLARLEKELAELAAELAE-LQQEAEELEALIARLEAEAAAAA 240


                  ..
gi 386767627  940 EK 941
Cdd:COG4942   241 ER 242

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

833-1110

7.85e-06

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.22 E-value: 7.85e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   833 EEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFE------------------------RQLEEEQRTQAEQRQKL- 887
Cdd:pfam12128  214 PKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNtlesaelrlshlhfgyksdetliaSRQEERQETSAELNQLLr 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   888 --TEEFAAERDRLQSELR-QRENEHQARRQ-EALREQEQELEQAKFEMQERMAKQEEKYQN--------------RVNTI 949
Cdd:pfam12128  294 tlDDQWKEKRDELNGELSaADAAVAKDRSElEALEDQHGAFLDADIETAAADQEQLPSWQSelenleerlkaltgKHQDV 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   950 EQQYQAdfELWKTEHENKTKLAQAEKEnaiRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKyekdlvlaes 1029
Cdd:pfam12128  374 TAKYNR--RRSKIKEQNNRDIAGIKDK---LAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE---------- 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1030 vEKSLREKYAETRGKLAEADA------QVRNSQAEVKQLQLELSHSKKMCGDIIMER---DRLRDNLNADIQSELGVLNE 1100
Cdd:pfam12128  439 -EYRLKSRLGELKLRLNQATAtpelllQLENFDERIERAREEQEAANAEVERLQSELrqaRKRRDQASEALRQASRRLEE 517

                          330
                   ....*....|
gi 386767627  1101 RhKQEMDQLQ 1110
Cdd:pfam12128  518 R-QSALDELE 526

PRK00409

recombination and DNA strand exchange inhibitor protein; Reviewed

855-976

1.29e-05

recombination and DNA strand exchange inhibitor protein; Reviewed

Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 49.44 E-value: 1.29e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  855 EAIIEKERTAI---RERFERQLE--EEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKf 929
Cdd:PRK00409  501 ENIIEEAKKLIgedKEKLNELIAslEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAI- 579

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 386767627  930 emqeRMAKQE-EKYQNRVNTIEQQYQADFELWKTEhENKTKLAQAEKE 976
Cdd:PRK00409  580 ----KEAKKEaDEIIKELRQLQKGGYASVKAHELI-EARKRLNKANEK 622

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

833-974

1.33e-05

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 49.18 E-value: 1.33e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   833 EEARTKHEQIETS--IRESCAQDREAIIEkertAIRERFERQLEEEQRTQAEQR-QKLTEEFAAERDRLQSE-------- 901
Cdd:pfam15709  359 EQRRLQQEQLERAekMREELELEQQRRFE----EIRLRKQRLEEERQRQEEEERkQRLQLQAAQERARQQQEefrrklqe 434

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627   902 LRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEK----YQNRVNTIEQQYQADFELWKTEHENKTKLAQAE 974
Cdd:pfam15709  435 LQRKKQQEEAERAEAEKQRQKELEMQLAEEQKRLMEMAEEerleYQRQKQEAEEKARLEAEERRQKEEEAARLALEE 511

Mitofilin

pfam09731

Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ...

666-948

1.57e-05

Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 48.98 E-value: 1.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   666 QLARRVIALSLRANElaNAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRH----QGFIEQLLKDKGS 741
Cdd:pfam09731  139 SKAESATAVAKEAKD--DAIQAVKAHTDSLKEASDTAEISREKATDSALQKAEALAEKLKEVInlakQSEEEAAPPLLDA 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   742 LCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKirRERWVRENTKKIKELTV------KGLEAEINKMNCDHQR 815
Cdd:pfam09731  217 APETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASE--RIVFQQELVSIFPDIIPvlkednLLSNDDLNSLIAHAHR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   816 EVTELKRthQMQLLDALEEARtkheqIETSIRESCAQDREAIiEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFaaeR 895
Cdd:pfam09731  295 EIDQLSK--KLAELKKREEKH-----IERALEKQKEELDKLA-EELSARLEEVRAADEAQLRLEFEREREEIRESY---E 363

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 386767627   896 DRLQSELRQRENEHQARRQEALREQEQELE-QAKFEMQERMAKQEEKYQNRVNT 948
Cdd:pfam09731  364 EKLRTELERQAEAHEEHLKDVLVEQEIELQrEFLQDIKEKVEEERAGRLLKLNE 417

YqiK

COG2268

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

829-1014

1.58e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];

Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 48.72 E-value: 1.58e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  829 LDALEEARTKhEQIETSIRESCAQDREAII---EKERTAIRERFERQLEEEQRTQAEQRqklteefaAERDRLQSELRQR 905
Cdd:COG2268   186 LDALGRRKIA-EIIRDARIAEAEAERETEIaiaQANREAEEAELEQEREIETARIAEAE--------AELAKKKAEERRE 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  906 ENEHQARRQEALREQEQELEQAKfEMQERMAKQEEkyQNRVNTIEQQYQAdfelwKTEHENKTKLAQAEKENAIRQHyRA 985
Cdd:COG2268   257 AETARAEAEAAYEIAEANAEREV-QRQLEIAERER--EIELQEKEAEREE-----AELEADVRKPAEAEKQAAEAEA-EA 327

                         170       180
                  ....*....|....*....|....*....
gi 386767627  986 ERDRQLDELVVrmEADALQHKEEHELKMN 1014
Cdd:COG2268   328 EAEAIRAKGLA--EAEGKRALAEAWNKLG 354

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

910-1150

1.63e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.63e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  910 QARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE----NAIRQHYRA 985
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElaelEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  986 ERDRQLDELVVRMeaDALQhkeehelKMNRlkEKYEKDLVLAESVEKSLR-----EKYAETRGKLAEadaQVRNSQAEVK 1060
Cdd:COG4942    98 ELEAQKEELAELL--RALY-------RLGR--QPPLALLLSPEDFLDAVRrlqylKYLAPARREQAE---ELRADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1061 QLQLELSHskkmcgdiimERDRLRdNLNADIQSELGVLnERHKQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLK 1140
Cdd:COG4942   164 ALRAELEA----------ERAELE-ALLAELEEERAAL-EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|
gi 386767627 1141 LNAVIRQQRK 1150
Cdd:COG4942   232 LEAEAAAAAE 241

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

666-1121

2.26e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 2.26e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  666 QLARRVIALSLRANELANAIHMSK----EHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKG- 740
Cdd:COG4913   259 ELAERYAAARERLAELEYLRAALRlwfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGd 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  741 ---SLCEKVAALTRRLESQNQAWEhRLETELARTKETTMAGEKI---RRERWVR-----ENTKKIKELTVKGLEAEINKM 809
Cdd:COG4913   339 rleQLEREIERLERELEERERRRA-RLEALLAALGLPLPASAEEfaaLRAEAAAllealEEELEALEEALAEAEAALRDL 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  810 NCDH---QREVTELKRT------HQMQLLDALEEA-----------------RTKHEQIETSI-------------RESC 850
Cdd:COG4913   418 RRELrelEAEIASLERRksnipaRLLALRDALAEAlgldeaelpfvgelievRPEEERWRGAIervlggfaltllvPPEH 497

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  851 AQDREAIIEKERTAIRERFER---QLEEEQRTQAEQRQ---KLTEEFAAERDRLQSELRQREN----------------- 907
Cdd:COG4913   498 YAAALRWVNRLHLRGRLVYERvrtGLPDPERPRLDPDSlagKLDFKPHPFRAWLEAELGRRFDyvcvdspeelrrhprai 577

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  908 -------------EHQARRQ---------------EALREQEQELEQAKFEMQERMAKQEEKYQNRvntieQQYQADFEL 959
Cdd:COG4913   578 tragqvkgngtrhEKDDRRRirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDAL-----QERREALQR 652

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  960 WKTEHENKTKLAQAEKEnairqhyRAERDRQLDELvvRMEADALQhkeehelkmnRLKEKYEKdlvlAESVEKSLREKYA 1039
Cdd:COG4913   653 LAEYSWDEIDVASAERE-------IAELEAELERL--DASSDDLA----------ALEEQLEE----LEAELEELEEELD 709

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1040 ETRGKLAEADAQVRNSQAEVKQLQLELShskkmcGDIIMERDRLRDNLNADIQSELGvlNERHKQEMDQLQKRVHQTIQR 1119
Cdd:COG4913   710 ELKGEIGRLEKELEQAEEELDELQDRLE------AAEDLARLELRALLEERFAAALG--DAVERELRENLEERIDALRAR 781


                  ..
gi 386767627 1120 QE 1121
Cdd:COG4913   782 LN 783

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

866-1067

3.08e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 3.08e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  866 RERFERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQREnehqaRRQEALREQEQELEQAKFEMQERMA---KQEEKY 942
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKEL-AALKKEEKALLKQLAALE-----RRIAALARRIRALEQELAALEAELAeleKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  943 QNRVNTIEQQYQADF-ELWKTEHENKTKL-------AQAEKENAIRQHYRAERDRQLDELVVRME--ADALQHKEEHELK 1012
Cdd:COG4942    96 RAELEAQKEELAELLrALYRLGRQPPLALllspedfLDAVRRLQYLKYLAPARREQAEELRADLAelAALRAELEAERAE 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 386767627 1013 MNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELS 1067
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230

FAM184

pfam15665

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

806-1024

3.17e-05

Family with sequence similarity 184, A and B; The function of FAM184 is not known.

Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 46.19 E-value: 3.17e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   806 INKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAiiekertairerfeRQLEEEQRTQAEQRQ 885
Cdd:pfam15665    5 LNTKNDEHEAEIQALKEAHEEEIQQILAETREKILQYKSKIGEELDLKRRI--------------QTLEESLEQHERMKR 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   886 KLTEEFAAERDRLQSELRQRENEHQARrqeaLREQEQELEQAKFEMQER-------MAKQEEKYQNRVNTIEQQYQADFE 958
Cdd:pfam15665   71 QALTEFEQYKRRVEERELKAEAEHRQR----VVELSREVEEAKRAFEEKlesfeqlQAQFEQEKRKALEELRAKHRQEIQ 146

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627   959 LWKTEHENKTKLAQAEKENaIRQHYRAERDrQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDL 1024
Cdd:pfam15665  147 ELLTTQRAQSASSLAEQEK-LEELHKAELE-SLRKEVEDLRKEKKKLAEEYEQKLSKAQAFYEREL 210

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

770-1143

3.20e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.43 E-value: 3.20e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   770 RTKETTMAGEKIRRERWVRENTKKIKeltvKGLEAEINKMncDHQREVTELKRTHQMQLLDALEEARTKHEQietSIRES 849
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKK----KSLHGKAELL--TLRSQLLTLCTPCMPDTYHERKQVLEKELK---HLREA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   850 CAQDRE--AIIEKERTAIRERFERQLE-EEQRTQAEQRQKLTEEFAAERDRLQ---------------SELRQRENEHQA 911
Cdd:TIGR00618  235 LQQTQQshAYLTQKREAQEEQLKKQQLlKQLRARIEELRAQEAVLEETQERINrarkaaplaahikavTQIEQQAQRIHT 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   912 RRQEALREQEQELEQAKFEMQERMAKQEEKyqnrvnTIEQQYQADFELWKTEHENKTK-LAQAEKENAIRQHYRAERdrq 990
Cdd:TIGR00618  315 ELQSKMRSRAKLLMKRAAHVKQQSSIEEQR------RLLQTLHSQEIHIRDAHEVATSiREISCQQHTLTQHIHTLQ--- 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   991 ldelvvrmeadalQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAEtRGKLAEADAQVRNSQAEVKQLQLELSHSK 1070
Cdd:TIGR00618  386 -------------QQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDL-QGQLAHAKKQQELQQRYAELCAAAITCTA 451

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 386767627  1071 KMCGDIIMERDRLRDNLNADIQSElgvlnerhkQEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNA 1143
Cdd:TIGR00618  452 QCEKLEKIHLQESAQSLKEREQQL---------QTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNP 515

TPH

pfam13868

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...

761-1019

3.63e-05

Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 47.22 E-value: 3.63e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   761 EHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHE 840
Cdd:pfam13868   87 QKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYLKEKAE 166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   841 QIETSIREscaqdrEAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQ 920
Cdd:pfam13868  167 REEEREAE------REEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   921 EQELEQAKFEMQERMAKQEEKYQNRVntieqqyqadfeLWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEA 1000
Cdd:pfam13868  241 REEQIELKERRLAEEAEREEEEFERM------------LRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAA 308

                          250
                   ....*....|....*....
gi 386767627  1001 DALQHKEEHELKMNRLKEK 1019
Cdd:pfam13868  309 EREEELEEGERLREEEAER 327

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

864-1062

3.74e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.49 E-value: 3.74e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  864 AIRERFERQLEEE--QRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEM----QERMAK 937
Cdd:PRK09510   59 AVVEQYNRQQQQQksAKRAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAAlkqkQAEEAA 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  938 QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAirqhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLK 1017
Cdd:PRK09510  139 AKAAAAAKAKAEAEAKRAAAAAKKAAAEAKKKAEAEAAKKA-----AAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAA 213

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 386767627 1018 EKYEKDLVLAESV-EKSLREKYAETRGKLAEADAQVRNSQAEVKQL 1062
Cdd:PRK09510  214 EAKKKAAAEAKAAaAKAAAEAKAAAEKAAAAKAAEKAAAAKAAAEV 259

mukB

chromosome partition protein MukB;

813-1137

4.27e-05

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.03 E-value: 4.27e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  813 HQREVTELKRthqmQLLDALEEARTKHEQIETSIRESCAQ-DREAIIEKERTAIRERFerQLEEEQRTQAEQRQKLTEEF 891
Cdd:PRK04863  284 HLEEALELRR----ELYTSRRQLAAEQYRLVEMARELAELnEAESDLEQDYQAASDHL--NLVQTALRQQEKIERYQADL 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  892 AAERDRL--QSELRQRENEHQARRQEALREQEQELEQAK---------FEMQERMAKQeekYQNRVNTIEQQYQ----AD 956
Cdd:PRK04863  358 EELEERLeeQNEVVEEADEQQEENEARAEAAEEEVDELKsqladyqqaLDVQQTRAIQ---YQQAVQALERAKQlcglPD 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  957 FEL-----WKTEHENKTKLA-----QAEK-----ENAIRQHYRAErdrqldELVVRMeADALQHKEEHElKMNRLKEKYE 1021
Cdd:PRK04863  435 LTAdnaedWLEEFQAKEQEAteellSLEQklsvaQAAHSQFEQAY------QLVRKI-AGEVSRSEAWD-VARELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1022 KDLVLAESVEkSLREKYAETRGKLaeadaqvrNSQAEVKQLQLELSHskkmcgdiimerdrlRDNLNADIQSELGVLNER 1101
Cdd:PRK04863  507 EQRHLAEQLQ-QLRMRLSELEQRL--------RQQQRAERLLAEFCK---------------RLGKNLDDEDELEQLQEE 562

                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 386767627 1102 HKQEMDQLQKRVHQTIQRQEET---IEILKGDNDALRQQ 1137
Cdd:PRK04863  563 LEARLESLSESVSEARERRMALrqqLEQLQARIQRLAAR 601

tolA

PRK09510

cell envelope integrity inner membrane protein TolA; Provisional

830-978

5.16e-05

cell envelope integrity inner membrane protein TolA; Provisional

Pssm-ID: 236545 [Multi-domain] Cd Length: 387 Bit Score: 47.11 E-value: 5.16e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  830 DALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAErdrlQSELRQRENEH 909
Cdd:PRK09510   76 RAEEQRKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAK----AAAAAKAKAEA 151

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767627  910 QARRQEALREQEQElEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA 978
Cdd:PRK09510  152 EAKRAAAAAKKAAA-EAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKA 219

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

828-1059

5.58e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.45 E-value: 5.58e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  828 LLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQKLTEEFAAERDRLqSELRQREN 907
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEA------EEKEEEYAELQEELEELEEELEELEAEL-EELREELE 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  908 EHqaRRQEALREQEQELEQAKFEMQErmakqeekYQNRVNTIEQQYQAdfelwktEHENKTKLAQAEKEnaiRQHYRAER 987
Cdd:COG4717   120 KL--EKLLQLLPLYQELEALEAELAE--------LPERLEELEERLEE-------LRELEEELEELEAE---LAELQEEL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 386767627  988 DRQLDELVVRMEADALQHKEEHELKMNRLKEkYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEV 1059
Cdd:COG4717   180 EELLEQLSLATEEELQDLAEELEELQQRLAE-LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARL 250

Caldesmon

pfam02029

Caldesmon;

840-1128

6.00e-05

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 47.17 E-value: 6.00e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   840 EQIETSIRESCAQDREAIIEKERTAIRERfERQLEEEQRTQAEQRQKLTEEFAA--ERDRLQSELRQRENEHQARRQEAL 917
Cdd:pfam02029    5 EEAARERRRRAREERRRQKEEEEPSGQVT-ESVEPNEHNSYEEDSELKPSGQGGldEEEAFLDRTAKREERRQKRLQEAL 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   918 REQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDrqldelvvR 997
Cdd:pfam02029   84 ERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEVRQAEE--------E 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   998 MEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAeadAQVRNSQAEVKQLQLELSHSKKMCGDII 1077
Cdd:pfam02029  156 GEEEEDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGH---PEVKSQNGEEEVTKLKVTTKRRQGGLSQ 232

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 386767627  1078 MERDRLRDNLNADIQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIEILK 1128
Cdd:pfam02029  233 SQEREEEAEVFLEAEQKLEELRRRRQEKESEEFEKLRQKQQEAELELEELK 283

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

999-1150

6.23e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.32 E-value: 6.23e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  999 EADALQHK-EEHELKMNRLKEKYekDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLELSHSKKMCGDI- 1076
Cdd:COG3206   183 QLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELl 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1077 ----IMERDRLRDNLNADIQSELGVLNERH------KQEMDQLQKRVHQTIQRQEETIEIlkgDNDALRQQCLKLNAVIR 1146
Cdd:COG3206   261 qspvIQQLRAQLAELEAELAELSARYTPNHpdvialRAQIAALRAQLQQEAQRILASLEA---ELEALQAREASLQAQLA 337


                  ....
gi 386767627 1147 QQRK 1150
Cdd:COG3206   338 QLEA 341

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

673-1011

6.81e-05

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.27 E-value: 6.81e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   673 ALSLRANELANAIHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRDQKKHYEEV----VTRHQGFIEQllkdkgSLCEKVAA 748
Cdd:TIGR00618  574 ILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQdlqdVRLHLQQCSQ------ELALKLTA 647

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   749 LTRRLEsqNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQL 828
Cdd:TIGR00618  648 LHALQL--TLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIEN 725

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   829 LD--ALEEARTKHEQIETSIRESCAQDREAIieKERTAIRER-FERQLEEEQR-TQAEQRQKLTEEFAAERDRLQSELRQ 904
Cdd:TIGR00618  726 ASssLGSDLAAREDALNQSLKELMHQARTVL--KARTEAHFNnNEEVTAALQTgAELSHLAAEIQFFNRLREEDTHLLKT 803

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   905 RENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQnRVNTIEQQYQADfelwkteHENKTKLAQAEKENAiRQHYR 984
Cdd:TIGR00618  804 LEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSA-TLGEITHQLLKY-------EECSKQLAQLTQEQA-KIIQL 874

                          330       340
                   ....*....|....*....|....*..
gi 386767627   985 AERDRQLDELVVRMEADALQhKEEHEL 1011
Cdd:TIGR00618  875 SDKLNGINQIKIQFDGDALI-KFLHEI 900

ClpA

COG0542

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...

822-939

7.13e-05

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.00 E-value: 7.13e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  822 RTHQMQLLDALEEARTKHEQIETsirescaqDREAIIEKERTAIRERFERqLEEEQRTQAEQRQKLTEEFAAERDRLQSE 901
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEI--------EKEALKKEQDEASFERLAE-LRDELAELEEELEALKARWEAEKELIEEI 473

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 386767627  902 LRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQE 939
Cdd:COG0542   474 QELKEELEQRYGKIPELEKELAELEEELAELAPLLREE 511

PRK07353

F0F1 ATP synthase subunit B'; Validated

860-927

7.77e-05

F0F1 ATP synthase subunit B'; Validated

Pssm-ID: 235999 [Multi-domain] Cd Length: 140 Bit Score: 43.84 E-value: 7.77e-05

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 386767627  860 KERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSE-LRQRENEHQARRQEALREQEQELEQA 927
Cdd:PRK07353   49 KERLAEAEKLEAQYEQQLASARKQAQAVIAEAEAEADKLAAEaLAEAQAEAQASKEKARREIEQQKQAA 117

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

788-1002

1.07e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.07e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  788 RENTKKIKEL--TVKGLEAEINKMNCDHQREVTELKRTHQM--QLLDALEEARTKHEQIETSIREscAQDREAIIEKERT 863
Cdd:COG4942    23 AEAEAELEQLqqEIAELEKELAALKKEEKALLKQLAALERRiaALARRIRALEQELAALEAELAE--LEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  864 AIRERFERQLEEEQRTQAEQRQKL---TEEFAAERDRLQ-----SELRQRENEHQARRQEALREQEQELEQAKFEMQERM 935
Cdd:COG4942   101 AQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQylkylAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627  936 AKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnairqhyraerDRQLDELVVRMEADA 1002
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE-----------AEELEALIARLEAEA 236

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

826-938

1.37e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 45.26 E-value: 1.37e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  826 MQLLDALEEA--RTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRTQAEQRQKLTEEFAAERDRLQS 900
Cdd:cd16269   176 LQSKEAEAEAilQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQrelEQKLEDQERSYEEHLRQLKEKMEEERENLLK 255

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 386767627  901 ELrQRENEHQarrqeaLREQEQELEQAKFEMQERMAKQ 938
Cdd:cd16269   256 EQ-ERALESK------LKEQEALLEEGFKEQAELLQEE 286

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

852-1039

1.51e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 1.51e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  852 QDREAiiekertAIRERfERQLEEEQRTQAEQR--QKLTEE----FAA-------ERDRLQSELRQRENEHQARRQEALR 918
Cdd:COG3096   232 QDMEA-------ALREN-RMTLEAIRVTQSDRDlfKHLITEatnyVAAdymrhanERRELSERALELRRELFGARRQLAE 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  919 EQEQeleqakfemQERMAKQEEKYQNRVNTIEQQYQAdfelwKTEHENK--TKLAQAEKenaiRQHYRAErdrqLDELVV 996
Cdd:COG3096   304 EQYR---------LVEMARELEELSARESDLEQDYQA-----ASDHLNLvqTALRQQEK----IERYQED----LEELTE 361

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767627  997 RMEADALQHKEEHElkmnrLKEKYEKDLVLAESVEKSLREKYA 1039
Cdd:COG3096   362 RLEEQEEVVEEAAE-----QLAEAEARLEAAEEEVDSLKSQLA 399

PRK02224

DNA double-strand break repair Rad50 ATPase;

816-1068

1.55e-04

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.19 E-value: 1.55e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  816 EVTELKRTHQMQLLDALEEARTKHEQIETSIrESCAQDREAiiEKERTAIRERFER--QLEEEQRTQAEQRQKLTEEFAA 893
Cdd:PRK02224  468 ETIEEDRERVEELEAELEDLEEEVEEVEERL-ERAEDLVEA--EDRIERLEERREDleELIAERRETIEEKRERAEELRE 544

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  894 ERDRLQSELRQRENEHQARRQEAlreqEQELEQAKfEMQERMAKQEEKYQnRVNTIEQQYQADFELWKTEHENKTKLAQ- 972
Cdd:PRK02224  545 RAAELEAEAEEKREAAAEAEEEA----EEAREEVA-ELNSKLAELKERIE-SLERIRTLLAAIADAEDEIERLREKREAl 618

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  973 AEKENAIRQHYRAERDRQlDELVVRMEADALQHKEEHelkmnrlKEKYEKDLvlaESVEKSLREKyAETRGKLAEADAQV 1052
Cdd:PRK02224  619 AELNDERRERLAEKRERK-RELEAEFDEARIEEARED-------KERAEEYL---EQVEEKLDEL-REERDDLQAEIGAV 686

                         250
                  ....*....|....*.
gi 386767627 1053 RNSQAEVKQLQLELSH 1068
Cdd:PRK02224  687 ENELEELEELRERREA 702

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

666-957

1.63e-04

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 46.20 E-value: 1.63e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   666 QLARRVIALSLRANELANAIHMSKEHVFQLRG---------EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLL 736
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEelaeaeaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   737 KDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRrerwvrENTKKIKELT--VKGLEAEINKMNCDHQ 814
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE------ELESELEALLneRASLEEALALLRSELE 897

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   815 REVTELK--RTHQMQLLDALEEARTKHEQIETsirescaqdREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFA 892
Cdd:TIGR02168  898 ELSEELRelESKRSELRRELEELREKLAQLEL---------RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627   893 AERDRLqSELRQR-------------ENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADF 957
Cdd:TIGR02168  969 EARRRL-KRLENKikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNENF 1045

growth_prot_Scy

NF041483

polarized growth protein Scy;

750-1062

1.84e-04

polarized growth protein Scy;

Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 45.97 E-value: 1.84e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  750 TRRLESQNQAWEHRLETELARTkETTMAGEKIRRERwVRENTKKIKE--------LTVKGLEAE--INKMNCDHQR---E 816
Cdd:NF041483  433 AKTVELQEEARRLRGEAEQLRA-EAVAEGERIRGEA-RREAVQQIEEaartaeelLTKAKADADelRSTATAESERvrtE 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  817 VTELKRTHQMQLLDALEEARTKHEQIETsirESCAQDREAIIEKERTAirerfeRQLEEEQRTQAEQRQkltEEFAAERD 896
Cdd:NF041483  511 AIERATTLRRQAEETLERTRAEAERLRA---EAEEQAEEVRAAAERAA------RELREETERAIAARQ---AEAAEELT 578

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  897 RLQSELRQRenehQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKE 976
Cdd:NF041483  579 RLHTEAEER----LTAAEEALADARAEAERIRREAAEETERLRTEAAERIRTLQAQAEQEAERLRTEAAADASAARAEGE 654

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  977 NA---IRQHYRAERDRQLDELV-----VRMEADALQHK--EEHELKMNRLKEKYEKDLVLAESVEKSLREKYAETRGK-- 1044
Cdd:NF041483  655 NVavrLRSEAAAEAERLKSEAQesadrVRAEAAAAAERvgTEAAEALAAAQEEAARRRREAEETLGSARAEADQERERar 734

                         330       340
                  ....*....|....*....|....
gi 386767627 1045 ------LAEADAQVRNSQAEVKQL 1062
Cdd:NF041483  735 eqseelLASARKRVEEAQAEAQRL 758

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

851-1067

2.15e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 44.84 E-value: 2.15e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   851 AQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEF-AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKF 929
Cdd:TIGR02794   64 KKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAkQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERK 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   930 EMQERMAKQEEKyqnrvNTIEQQYQAdfelwKTEHENKTKLAQAEKENAirqhyrAERDRQLDELVVRMEADALQHKEEH 1009
Cdd:TIGR02794  144 AKEEAAKQAEEE-----AKAKAAAEA-----KKKAEEAKKKAEAEAKAK------AEAEAKAKAEEAKAKAEAAKAKAAA 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627  1010 ELKMNRLKEKYEKDLVLAESVEKSLRekyAETRGKLAEADAQVRNSQAEVKQLQLELS 1067
Cdd:TIGR02794  208 EAAAKAEAEAAAAAAAEAERKADEAE---LGDIFGLASGSNAEKQGGARGAAAGSEVD 262

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

864-1066

2.25e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.39 E-value: 2.25e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  864 AIRERFERQLEEEQRTQAEQRQKLTEEfaaERDRLQSELRQRENEHQARRQE----ALREQEQELEQAKFEMQERMAK-- 937
Cdd:COG3206   156 ALAEAYLEQNLELRREEARKALEFLEE---QLPELRKELEEAEAALEEFRQKnglvDLSEEAKLLLQQLSELESQLAEar 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  938 -QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDE--LVVRMEA--DALQHKEEHELK 1012
Cdd:COG3206   233 aELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNhpDVIALRAqiAALRAQLQQEAQ 312

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 386767627 1013 mnRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQvrnsQAEVKQLQLEL 1066
Cdd:COG3206   313 --RILASLEAELEALQAREASLQAQLAQLEARLAELPEL----EAELRRLEREV 360

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

732-933

2.50e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 2.50e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  732 IEQLLKDKGSLCEKVAALTRRLESQNQAWEHRLETELARTKETTmagekiRRERWVRENTKKIKELTVKGLEAEINKMnc 811
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA------RLEAALRRAVTLAGRLREVTLEGEGGSA-- 658

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  812 dhQREVTELKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEF 891
Cdd:COG1196   659 --GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 386767627  892 AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQE 933
Cdd:COG1196   737 LLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778

MAP7

pfam05672

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is ...

847-951

2.85e-04

MAP7 (E-MAP-115) family; The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilising protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.

Pssm-ID: 461709 [Multi-domain] Cd Length: 153 Bit Score: 42.34 E-value: 2.85e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   847 RESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQ---- 922
Cdd:pfam05672   27 REREEQERLEKEEEERLRKEELRRRAEEERARREEEARRLEEERRREEEERQRKAEEEAEEREQREQEEQERLQKQkeea 106

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 386767627   923 ------ELEQAKFEMQERMAKQEEKYQNRVNTIEQ 951
Cdd:pfam05672  107 eakareEAERQRQEREKIMQQEEQERLERKKRIEE 141

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

833-1013

2.89e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 44.94 E-value: 2.89e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   833 EEARTKHEQIETSIRESCAQDREAIIEKERTairERFERQLEEEQRTQAE------QRQKLTEEFAAERDRLQSELRQRE 906
Cdd:pfam15709  341 ERAEMRRLEVERKRREQEEQRRLQQEQLERA---EKMREELELEQQRRFEeirlrkQRLEEERQRQEEEERKQRLQLQAA 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   907 NEHQARRQEALREQEQELEQAKfemQERMAKQEEKYQNRVNTIEQQYQAdfelwktEHENKTKLAQAEKENAIRQHYRAE 986
Cdd:pfam15709  418 QERARQQQEEFRRKLQELQRKK---QQEEAERAEAEKQRQKELEMQLAE-------EQKRLMEMAEEERLEYQRQKQEAE 487

                          170       180
                   ....*....|....*....|....*..
gi 386767627   987 RDRQLdelvvrmEADALQHKEEHELKM 1013
Cdd:pfam15709  488 EKARL-------EAEERRQKEEEAARL 507

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

666-1065

3.63e-04

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 44.50 E-value: 3.63e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   666 QLARRVIALSLRANELANAIHMSKEHVFQLRgEKQKslraEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEK 745
Cdd:pfam07888   70 QWERQRRELESRVAELKEELRQSREKHEELE-EKYK----ELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQR 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   746 VaaLTRrlesqnqawehrlETELARTKETTmagEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQrevtELKRTHQ 825
Cdd:pfam07888  145 V--LER-------------ETELERMKERA---KKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ----ELRNSLA 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   826 MQLLDALeeaRTKHEQIETSIRESCAQDREAIIEKERTAIRERFERqLEEEQRTQAEQRQKLtEEFAAERDRLQSELrqr 905
Cdd:pfam07888  203 QRDTQVL---QLQDTITTLTQKLTTAHRKEAENEALLEELRSLQER-LNASERKVEGLGEEL-SSMAAQRDRTQAEL--- 274

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   906 eneHQARRQEAlrEQEQELEQAKFEMQERMAKqeekyqnrvntieqqyqadfelWKTEHENKTKLAQAEKEnairqhyra 985
Cdd:pfam07888  275 ---HQARLQAA--QLTLQLADASLALREGRAR----------------------WAQERETLQQSAEADKD--------- 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   986 eRDRQLDELVVRMEAdALQhkeehELKMNRLKEKYEkdlvLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLQLE 1065
Cdd:pfam07888  319 -RIEKLSAELQRLEE-RLQ-----EERMEREKLEVE----LGREKDCN-RVQLSESRRELQELKASLRVAQKEKEQLQAE 386

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

825-955

3.85e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 3.85e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  825 QMQLLDA---LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERF---ERQLEEEQRT--------QA--EQRQKLT 888
Cdd:COG3206   225 ESQLAEAraeLAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLaelEAELAELSARytpnhpdvIAlrAQIAALR 304

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627  889 EEFAAERDRLQSELRQrENEHQARRQEALREQEQELEQAKFEMQERMAKQEEkYQNRVNTIEQQYQA 955
Cdd:COG3206   305 AQLQQEAQRILASLEA-ELEALQAREASLQAQLAQLEARLAELPELEAELRR-LEREVEVARELYES 369

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

763-1125

3.90e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 44.96 E-value: 3.90e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   763 RLETELARTKETTMagEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDhQREVTELKRT-------HQMQLLDALEEA 835
Cdd:pfam02463  170 KKKEALKKLIEETE--NLAELIIDLEELKLQELKLKEQAKKALEYYQLKE-KLELEEEYLLyldylklNEERIDLLQELL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   836 RTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERdRLQSELRQRENEHQARRQE 915
Cdd:pfam02463  247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLE-RRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   916 ALREQEQELEQAKFEMQErMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnairqhyRAERDRQLDELV 995
Cdd:pfam02463  326 AEKELKKEKEEIEELEKE-LKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER-------LSSAAKLKEEEL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   996 VRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKyaetrgklaeaDAQVRNSQAEVKQLQLELSHSKKMCGD 1075
Cdd:pfam02463  398 ELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI-----------ELKQGKLTEEKEELEKQELKLLKDELE 466

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 386767627  1076 IIMERDRLrdnlnadiQSELGVLNERHKQEMDQLQKRVHQTIQRQEETIE 1125
Cdd:pfam02463  467 LKKSEDLL--------KETQLVKLQEQLELLLSRQKLEERSQKESKARSG 508

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

666-1066

4.42e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.54 E-value: 4.42e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  666 QLARRVIALSLRANELANAIHMSKEHvfqlRGEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSLCEK 745
Cdd:COG1196   334 ELEEELEELEEELEEAEEELEEAEAE----LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  746 VAALTRRLESQNQAWEHRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGLEAEINKMNCDHQREVTELKRTHQ 825
Cdd:COG1196   410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  826 MQLLDALEEARTKHEQIETSIRESCAQDREAII-----------EKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAE 894
Cdd:COG1196   490 AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  895 RD--------------RLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERM----AKQEEKYQNRVNTIEQQYQAD 956
Cdd:COG1196   570 KAgratflpldkirarAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlvAARLEAALRRAVTLAGRLREV 649

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  957 FELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLRE 1036
Cdd:COG1196   650 TLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 386767627 1037 KYAETRGKLAE-----------------ADAQVRNSQAEVKQLQLEL 1066
Cdd:COG1196   730 LEAEREELLEElleeeelleeealeelpEPPDLEELERELERLEREI 776

GBP_C

cd16269

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...

832-955

4.62e-04

Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 43.72 E-value: 4.62e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  832 LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRtqaEQRQKLTEEfaaERdRLQSELRQRENEHQA 911
Cdd:cd16269   176 LQSKEAEAEAILQADQALTEKEKEIEAERAKAEAAEQERKLLEEQQR---ELEQKLEDQ---ER-SYEEHLRQLKEKMEE 248

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 386767627  912 RRQEALREQEQELEQakfEMQERMAKQEEKYQNRVNTIEQQYQA 955
Cdd:cd16269   249 ERENLLKEQERALES---KLKEQEALLEEGFKEQAELLQEEIRS 289

Caldesmon

pfam02029

Caldesmon;

698-943

5.45e-04

Caldesmon;

Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 44.09 E-value: 5.45e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   698 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKDKGSlCEKVAALTRRLESQNQAW---EHRLETELARTKET 774
Cdd:pfam02029   84 ERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSRLGR-YKEEETEIREKEYQENKWsteVRQAEEEGEEEEDK 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   775 TMAGEKIRRERWVRENTKKI---KELTVKgleaEINKMNCDHQREVTELKrTHQMQLLDALEEARTKHEQIETSIRESCA 851
Cdd:pfam02029  163 SEEAEEVPTENFAKEEVKDEkikKEKKVK----YESKVFLDQKRGHPEVK-SQNGEEEVTKLKVTTKRRQGGLSQSQERE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   852 QDREAIIEKERTAIRERFERQ-LEEEQRTQAEQRQKLTEEFAAERDRLQSELRQ-RENEHQARRQEALREQ---EQELEQ 926
Cdd:pfam02029  238 EEAEVFLEAEQKLEELRRRRQeKESEEFEKLRQKQQEAELELEELKKKREERRKlLEEEEQRRKQEEAERKlreEEEKRR 317

                          250
                   ....*....|....*..
gi 386767627   927 AKFEMQERMAKQEEKYQ 943
Cdd:pfam02029  318 MKEEIERRRAEAAEKRQ 334

GBP_C

pfam02841

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...

866-994

6.10e-04

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.

Pssm-ID: 460721 [Multi-domain] Cd Length: 297 Bit Score: 43.04 E-value: 6.10e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   866 RERFERQLEEEQR--TQAEQ--RQKLTEEFAAERDRLQSE----LRQRENEHQARRQEALREQEQELEQAKFEMQERMAK 937
Cdd:pfam02841  157 RDKLEAKYNQVPRkgVKAEEvlQEFLQSKEAVEEAILQTDqaltAKEKAIEAERAKAEAAEAEQELLREKQKEEEQMMEA 236

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627   938 QEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDEL 994
Cdd:pfam02841  237 QERSYQEHVKQLIEKMEAEREQLLAEQERMLEHKLQEQEELLKEGFKTEAESLQKEI 293

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

881-1120

6.68e-04

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 43.30 E-value: 6.68e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   881 AEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEAlrEQEQELEQAKFEMQErmAKQEEkyQNRVNTIEQQYQADFELW 960
Cdd:TIGR02794   53 NRIQQQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQ--ARQKELEQRAAAEKA--AKQAE--QAAKQAEEKQKQAEEAKA 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   961 KTEHENKtklAQAEKENAIRQHYRAERDRqldELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLREKyAE 1040
Cdd:TIGR02794  127 KQAAEAK---AKAEAEAERKAKEEAAKQA---EEEAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAK-AE 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1041 TRGKLAEADAQVRNSQAevKQLQLELSHSKKMCGDIIMERDRLRDNLNADIQSelGVLNERHKQEMDQLQKRVHQTIQRQ 1120
Cdd:TIGR02794  200 AAKAKAAAEAAAKAEAE--AAAAAAAEAERKADEAELGDIFGLASGSNAEKQG--GARGAAAGSEVDKYAAIIQQAIQQN 275

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

799-1125

6.83e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.95 E-value: 6.83e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   799 VKGLEAEINKMNCDHQREVTELKRThQMQLLDALEEARTKHEQIeTSIRESCAQDREAIIEKERTAIRER-----FERQL 873
Cdd:pfam15921   87 VKDLQRRLNESNELHEKQKFYLRQS-VIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHELeaakcLKEDM 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   874 EEEQRTQAEQRQKLTEEFAAERDRLQSELRQREN-------EHQARR-----------QEALREQEQELEQAK---FEMQ 932
Cdd:pfam15921  165 LEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyEHDSMStmhfrslgsaiSKILRELDTEISYLKgriFPVE 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   933 ERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENK----TKLAQAEKENA---------IRQHYRAERD---RQLDEL-- 994
Cdd:pfam15921  245 DQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEitglTEKASSARSQAnsiqsqleiIQEQARNQNSmymRQLSDLes 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   995 -VVRMEADALQHKEEHELKMnrlkEKYEKDLVLAES---VEKSLREKYAETRGKLaeaDAQVRNSQAEV----KQLQLEL 1066
Cdd:pfam15921  325 tVSQLRSELREAKRMYEDKI----EELEKQLVLANSeltEARTERDQFSQESGNL---DDQLQKLLADLhkreKELSLEK 397

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627  1067 SHSKKM----CGDIIMeRDRLR---DNLNADIQsELGVLNERHKQEMDQLQKRVHQTIQRQEETIE 1125
Cdd:pfam15921  398 EQNKRLwdrdTGNSIT-IDHLRrelDDRNMEVQ-RLEALLKAMKSECQGQMERQMAAIQGKNESLE 461

PRK12704

phosphodiesterase; Provisional

792-956

6.87e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.61 E-value: 6.87e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  792 KKIKELTVKGLEAEINKMNCDHQREVTELKRTHQMQLLDALEEARTKHEQiETSIRESCAQDREA-IIEKErtairERFE 870
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEK-ELRERRNELQKLEKrLLQKE-----ENLD 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  871 RQLEEeqrtqAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQ----ELEQAKFEMQERMaKQEEKYQ--N 944
Cdd:PRK12704  100 RKLEL-----LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisglTAEEAKEILLEKV-EEEARHEaaV 173

                         170
                  ....*....|..
gi 386767627  945 RVNTIEQQYQAD 956
Cdd:PRK12704  174 LIKEIEEEAKEE 185

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

673-1128

7.13e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.95 E-value: 7.13e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   673 ALSLRANELANAIHMSKEHVFQLrgekQKSLRAEKSTAAAKLrdqkkhyEEVVTRHQGFIEQLLKDKGSlceKVAALTRR 752
Cdd:pfam15921  221 AISKILRELDTEISYLKGRIFPV----EDQLEALKSESQNKI-------ELLLQQHQDRIEQLISEHEV---EITGLTEK 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   753 LESqnqawehrletelARTKETTMAGE-KIRRERWVRENTKKIKEL-----TVKGLEAEINKMNCDHQREVTELKRthQM 826
Cdd:pfam15921  287 ASS-------------ARSQANSIQSQlEIIQEQARNQNSMYMRQLsdlesTVSQLRSELREAKRMYEDKIEELEK--QL 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   827 QLLDA-LEEARTKHEQIEtsiRESCAQDREaiIEKERTAIRERferqlEEEQRTQAEQRQKLTEEFAAER---DRLQSEL 902
Cdd:pfam15921  352 VLANSeLTEARTERDQFS---QESGNLDDQ--LQKLLADLHKR-----EKELSLEKEQNKRLWDRDTGNSitiDHLRREL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   903 RQRENEHQarRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKT-------------- 968
Cdd:pfam15921  422 DDRNMEVQ--RLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTakkmtlessertvs 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   969 --KLAQAEKENAIR------QHYRAERDRQLDELV-VRMEADALQHKEEH----ELKMNR-------LKEKYEKDLVL-- 1026
Cdd:pfam15921  500 dlTASLQEKERAIEatnaeiTKLRSRVDLKLQELQhLKNEGDHLRNVQTEcealKLQMAEkdkvieiLRQQIENMTQLvg 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1027 -------AESVEKSLREK-YAETRGKLAE-------ADAQVRNSQAEVKQLQLEL-------SHSKKMCGDIIMERDRLR 1084
Cdd:pfam15921  580 qhgrtagAMQVEKAQLEKeINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKvklvnagSERLRAVKDIKQERDQLL 659

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 386767627  1085 DNLNADiQSELGVLNErhkqEMDQLQKRVHQTIQRQEETIEILK 1128
Cdd:pfam15921  660 NEVKTS-RNELNSLSE----DYEVLKRNFRNKSEEMETTTNKLK 698

DUF4670

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins ...

875-1065

8.37e-04

Domain of unknown function (DUF4670); This family of proteins is found in eukaryotes. Proteins in this family are typically between 373 and 763 amino acids in length.

Pssm-ID: 464815 [Multi-domain] Cd Length: 522 Bit Score: 43.40 E-value: 8.37e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   875 EEQRTQAEQRQKLT---EEFAAERDRL---QSELRQRENEHQARRQEALREQEQEleqaKFEMQERMAKQEEKYQNRV-- 946
Cdd:pfam15709  312 EEERSEEDPSKALLekrEQEKASRDRLraeRAEMRRLEVERKRREQEEQRRLQQE----QLERAEKMREELELEQQRRfe 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   947 -NTIEQQYQADFELWKTEHENKTKLA-QAEKENAIRQhyRAERDRQLDELVVRMEADALQHKEEHELKMNRLKEKY-EKD 1023
Cdd:pfam15709  388 eIRLRKQRLEEERQRQEEEERKQRLQlQAAQERARQQ--QEEFRRKLQELQRKKQQEEAERAEAEKQRQKELEMQLaEEQ 465

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 386767627  1024 LVLAESVEKS----LREKYAETRGKLAEADAQVRNSQAEVKQLQLE 1065
Cdd:pfam15709  466 KRLMEMAEEErleyQRQKQEAEEKARLEAEERRQKEEEAARLALEE 511

tolA_full

TIGR02794

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...

831-997

8.83e-04

Pssm-ID: 274303 [Multi-domain] Cd Length: 346 Bit Score: 42.91 E-value: 8.83e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   831 ALEEARTKHEQIETSIREScAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQ 910
Cdd:TIGR02794   79 EAEKQRAAEQARQKELEQR-AAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEEAAKQAEEEAK 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   911 ARRQEAlREQEQELEQAKFEmQERMAKQEEKYQNRVNtiEQQYQADFELWKTEHENKTKLAQAEKENAirqhyRAERDRQ 990
Cdd:TIGR02794  158 AKAAAE-AKKKAEEAKKKAE-AEAKAKAEAEAKAKAE--EAKAKAEAAKAKAAAEAAAKAEAEAAAAA-----AAEAERK 228


                   ....*..
gi 386767627   991 LDELVVR 997
Cdd:TIGR02794  229 ADEAELG 235

MARTX_Nterm

NF012221

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...

944-1124

9.68e-04

Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 43.67 E-value: 9.68e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  944 NRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA--IRQHYRAERDRQLDElvVRMEADALQHKEEHELKMNrlkEKYE 1021
Cdd:NF012221 1533 NVVATSESSQQADAVSKHAKQDDAAQNALADKERAeaDRQRLEQEKQQQLAA--ISGSQSQLESTDQNALETN---GQAQ 1607

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1022 KDLVLAES--VEKSLREK---------YAETRGklaEADAQVRNSQAE--VKQLQLELSHSKKMCGDIIME-RDRLRDNL 1087
Cdd:NF012221 1608 RDAILEESraVTKELTTLaqgldaldsQATYAG---ESGDQWRNPFAGglLDRVQEQLDDAKKISGKQLADaKQRHVDNQ 1684

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 386767627 1088 ----NADIQSELGVLN-ERHKQEMDQ-LQKRVHQTIQRQEETI 1124
Cdd:NF012221 1685 qkvkDAVAKSEAGVAQgEQNQANAEQdIDDAKADAEKRKDDAL 1727

PRK12705

hypothetical protein; Provisional

820-958

1.30e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.77 E-value: 1.30e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  820 LKRTHQMQLLDALEEARTKHEQIETSIRESCAQDREaiiEKERTAIRERFERQLEEEQRTQAEQRQ-------KLTEEFA 892
Cdd:PRK12705   31 LAKEAERILQEAQKEAEEKLEAALLEAKELLLRERN---QQRQEARREREELQREEERLVQKEEQLdaraeklDNLENQL 107

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627  893 AERDR-LQSELRQRENEHQARRQEALREQEQELEQAKFEMQERM-AKQEEKYQNRVNTIEQQYQADFE 958
Cdd:PRK12705  108 EEREKaLSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLdAELEEEKAQRVKKIEEEADLEAE 175

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

832-1053

1.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 1.31e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  832 LEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFErQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQA 911
Cdd:COG3206   184 LPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS-ELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQS 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  912 RRQEALREQEQELEQAKFEMQERMAKQEEKYQ---NRVNTIEQQYQAdfelwktehENKTKLAQAEKENAIRQHYRAERD 988
Cdd:COG3206   263 PVIQQLRAQLAELEAELAELSARYTPNHPDVIalrAQIAALRAQLQQ---------EAQRILASLEAELEALQAREASLQ 333

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 386767627  989 RQLDELVVRMEADAlqhkeEHELKMNRLKEKYEkdlvLAESVEKSLREKYAETRGKLAEADAQVR 1053
Cdd:COG3206   334 AQLAQLEARLAELP-----ELEAELRRLEREVE----VARELYESLLQRLEEARLAEALTVGNVR 389

Myosin_tail_1

pfam01576

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

698-1149

2.02e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.47 E-value: 2.02e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   698 EKQKSLRAEKSTAAAKLRDQKKHYEEVVtrhqGFIEQLLKDKGSLCEKVAALTRRLESQNQAWEhrletELARTKEttma 777
Cdd:pfam01576  510 EAKRNVERQLSTLQAQLSDMKKKLEEDA----GTLEALEEGKKRLQRELEALTQQLEEKAAAYD-----KLEKTKN---- 576

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   778 geKIRRErwvrentkkIKELTVkgleaeinkmNCDHQRevtelkrthqmQLLDALEEARTKHEQI---ETSIRESCAQDR 854
Cdd:pfam01576  577 --RLQQE---------LDDLLV----------DLDHQR-----------QLVSNLEKKQKKFDQMlaeEKAISARYAEER 624

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   855 EAI----IEKERTAIRerFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRqeALREQEQELEQAKFE 930
Cdd:pfam01576  625 DRAeaeaREKETRALS--LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELER--SKRALEQQVEEMKTQ 700

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   931 MQER----MAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKEnaIRQHyRAERDrqlDELVVRMEADALQHK 1006
Cdd:pfam01576  701 LEELedelQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQ--VREL-EAELE---DERKQRAQAVAAKKK 774

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1007 EEHELK--------MNRLKEKYEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNS-------QAEVKQLQLELSHSKK 1071
Cdd:pfam01576  775 LELDLKeleaqidaANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESekklknlEAELLQLQEDLAASER 854

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1072 MCGDIIMERDRLRDNLNADIQSELGVLNERHkqemdQLQKRVHQTIQRQEE---TIEILKGDNDALRQQCLKLNAVIRQQ 1148
Cdd:pfam01576  855 ARRQAQQERDELADEIASGASGKSALQDEKR-----RLEARIAQLEEELEEeqsNTELLNDRLRKSTLQVEQLTTELAAE 929


                   .
gi 386767627  1149 R 1149
Cdd:pfam01576  930 R 930

mukB

chromosome partition protein MukB;

864-996

2.19e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 2.19e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  864 AIRERFERQleEEQRTQAEQRQKLTEEFAAERDRLQSELRqreNEHQARRQEaLREQEQELE----QAKFEMQERMAKQE 939
Cdd:PRK04863  989 KLRQRLEQA--EQERTRAREQLRQAQAQLAQYNQVLASLK---SSYDAKRQM-LQELKQELQdlgvPADSGAEERARARR 1062

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627  940 EKYQNRVNTIEQQyqadfelwKTEHENKTKLAQAEKENAIRQHYRAERD-RQLDELVV 996
Cdd:PRK04863 1063 DELHARLSANRSR--------RNQLEKQLTFCEAEMDNLTKKLRKLERDyHEMREQVV 1112

OmpH

pfam03938

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...

853-953

2.29e-03

Pssm-ID: 461098 [Multi-domain] Cd Length: 140 Bit Score: 39.48 E-value: 2.29e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   853 DREAIIEK--ERTAIRERFER---QLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEaLREQEQELEQa 927
Cdd:pfam03938    6 DMQKILEEspEGKAAQAQLEKkfkKRQAELEAKQKELQKLYEELQKDGALLEEEREEKEQELQKKEQE-LQQLQQKAQQ- 83

                           90       100
                   ....*....|....*....|....*.
gi 386767627   928 kfEMQERMAKQEEKYQNRVNTIEQQY 953
Cdd:pfam03938   84 --ELQKKQQELLQPIQDKINKAIKEV 107

MukB

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

812-1093

2.41e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.25 E-value: 2.41e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  812 DHQREVTElKRTHQMQLLDALEEARTKHEQ--------IETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQ 883
Cdd:COG3096   272 DYMRHANE-RRELSERALELRRELFGARRQlaeeqyrlVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEKIE 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  884 RQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQAK---------FEMQERMAKQeekYQNRVNTIEQQYQ 954
Cdd:COG3096   351 RYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKsqladyqqaLDVQQTRAIQ---YQQAVQALEKARA 427

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  955 ---------ADFELWKTEH------------ENKTKLAQAEKenAIRQHYRA-ERDRQLDELVVRMEA-----DALQHKE 1007
Cdd:COG3096   428 lcglpdltpENAEDYLAAFrakeqqateevlELEQKLSVADA--ARRQFEKAyELVCKIAGEVERSQAwqtarELLRRYR 505

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1008 EHELKMNR---LKEKY---EKDLVLAESVEKSLREKYAETRGKLAEADaQVRNSQAEVKQLQLELSHSKKMCGDIIMERD 1081
Cdd:COG3096   506 SQQALAQRlqqLRAQLaelEQRLRQQQNAERLLEEFCQRIGQQLDAAE-ELEELLAELEAQLEELEEQAAEAVEQRSELR 584

                         330
                  ....*....|..
gi 386767627 1082 RLRDNLNADIQS 1093
Cdd:COG3096   585 QQLEQLRARIKE 596

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

788-978

2.59e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.74 E-value: 2.59e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  788 RENTKKIKELT--VKGLEAEINKMncdhQREVTELKRTHQmQLLDALEEARTKHEQIETSIrescaQDREAIIEKERTAI 865
Cdd:COG3883    19 QAKQKELSELQaeLEAAQAELDAL----QAELEELNEEYN-ELQAELEALQAEIDKLQAEI-----AEAEAEIEERREEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  866 RERFERQLEEEQ------------------------RTQAEQRQKLTEEFAAERDRLQSELRQRENEhqarrQEALREQE 921
Cdd:COG3883    89 GERARALYRSGGsvsyldvllgsesfsdfldrlsalSKIADADADLLEELKADKAELEAKKAELEAK-----LAELEALK 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627  922 QELEQAKFEMQERMAKQEEKYqNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENA 978
Cdd:COG3883   164 AELEAAKAELEAQQAEQEALL-AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219

PRK03918

DNA double-strand break repair ATPase Rad50;

854-1150

3.10e-03

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 3.10e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  854 REAIIEKERTAIRERFERQLEEEQRTQAEQRqKLTEEFAAERDRLQSELRQRENEHQARRQEALREQE-QELEQAKFEMQ 932
Cdd:PRK03918  187 RTENIEELIKEKEKELEEVLREINEISSELP-ELREELEKLEKEVKELEELKEEIEELEKELESLEGSkRKLEEKIRELE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  933 ERMAKQEEKYQN------RVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHYRAERDRQLDELVVRMEADALQHK 1006
Cdd:PRK03918  266 ERIEELKKEIEEleekvkELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1007 EEHEL--KMNRLKEK---YEKDLVLAESVEKSLREKYAETRGKLAEADAQVRNSQAEVkqlQLELSHSKKMCGDIIMERD 1081
Cdd:PRK03918  346 KLKELekRLEELEERhelYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEI---EEEISKITARIGELKKEIK 422

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 386767627 1082 RLRDNLNAdIQSELGV-------LNERHKQEmdqLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAVIRQQRK 1150
Cdd:PRK03918  423 ELKKAIEE-LKKAKGKcpvcgreLTEEHRKE---LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494

HCR

pfam07111

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...

736-1144

3.41e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.

Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 41.66 E-value: 3.41e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   736 LKDKGSLCEKVAALTRRLESQnqaweHRLETELARTKETTMAgEKIRRERWVRE-----NTKKIKELTVKGLE-----AE 805
Cdd:pfam07111   55 LEGSQALSQQAELISRQLQEL-----RRLEEEVRLLRETSLQ-QKMRLEAQAMEldalaVAEKAGQAEAEGLRaalagAE 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   806 INKMNCDH--QREVTELKRTHQMQlLDALEEArtkHEQIETSIrescaqdreaiiekerTAIRERFERQLEE-EQRTQAE 882
Cdd:pfam07111  129 MVRKNLEEgsQRELEEIQRLHQEQ-LSSLTQA---HEEALSSL----------------TSKAEGLEKSLNSlETKRAGE 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   883 QRQKLTEEFAAERDRLQSELRQRENEHQARRQEALRE------------QEQELEQAK-FEMQERMAKQEEKYQNRVNTI 949
Cdd:pfam07111  189 AKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKyvgeqvppevhsQTWELERQElLDTMQHLQEDRADLQATVELL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   950 EQQYQADFELWKTEHENKTKLAQ------AEKENAIRQHYRAERDRQLdELVVRMEADALQHKEEHELKMNRLKEKYEKd 1023
Cdd:pfam07111  269 QVRVQSLTHMLALQEEELTRKIQpsdslePEFPKKCRSLLNRWREKVF-ALMVQLKAQDLEHRDSVKQLRGQVAELQEQ- 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1024 lVLAESVEKSLREKyaetrgKLAEADAQVRNSQAEVKQLQLELSHSKkmcgdiimERDRLRDNLNADIQSELGVLnerhK 1103
Cdd:pfam07111  347 -VTSQSQEQAILQR------ALQDKAAEVEVERMSAKGLQMELSRAQ--------EARRRQQQQTASAEEQLKFV----V 407

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 386767627  1104 QEMDQLQKRVHQTIQRQEETIEILKGDNDALRQQCLKLNAV 1144
Cdd:pfam07111  408 NAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTI 448

PRK12705

hypothetical protein; Provisional

883-1019

3.45e-03

hypothetical protein; Provisional

Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.23 E-value: 3.45e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  883 QRQKLTEEFAAERDRLQSELRQRENEHQARRQEAL-REQEQELEQAKFEMQE------RMAKQEEKYQNRVNTIEQQYQA 955
Cdd:PRK12705   27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLlRERNQQRQEARREREElqreeeRLVQKEEQLDARAEKLDNLENQ 106

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627  956 DFELWKTEHENKTKLAQAEKENAiRQHYRA---ERDRQLDELVVRMEADAlqhKEEHELKMNRLKEK 1019
Cdd:PRK12705  107 LEEREKALSARELELEELEKQLD-NELYRVaglTPEQARKLLLKLLDAEL---EEEKAQRVKKIEEE 169

RNase_Y_N

pfam12072

RNase Y N-terminal region;

820-951

3.53e-03

RNase Y N-terminal region;

Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 39.87 E-value: 3.53e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   820 LKRTHQMQLLDALEEARtkhEQIETSIRESCAQDREAIIEKERTAIRERfeRQLEEEQRtqaEQRQKLteefaaerDRLQ 899
Cdd:pfam12072   21 RKSIAEAKIGSAEELAK---RIIEEAKKEAETKKKEALLEAKEEIHKLR--AEAERELK---ERRNEL--------QRQE 84

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627   900 SELRQRE------NEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQ 951
Cdd:pfam12072   85 RRLLQKEetldrkDESLEKKEESLEKKEKELEAQQQQLEEKEEELEELIEEQRQELER 142

HlpA

COG2825

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...

851-927

3.57e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 39.43 E-value: 3.57e-03

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 386767627  851 AQDREAIIEKERTAIRERfERQLEEEQRTQ-AEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQELEQA 927
Cdd:COG2825    52 FKKRQAELQKLEKELQAL-QEKLQKEAATLsEEERQKKERELQKKQQELQRKQQEAQQDLQKRQQELLQPILEKIQKA 128

rad50

TIGR00606

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

682-1083

3.93e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 3.93e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   682 ANAIHMSKEHVFQLRgEKQKSLRAEKSTAAAKLRDQKKHYEEVVTRhqgfiEQLLKDkgslCEKVAALTRRLESQNQAWE 761
Cdd:TIGR00606  736 QSIIDLKEKEIPELR-NKLQKVNRDIQRLKNDIEEQETLLGTIMPE-----EESAKV----CLTDVTIMERFQMELKDVE 805

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   762 HRLETELARTKETTMAGEKIRRERWVRENTKKIKELTVKGleAEINKMNCDHQREVTELK------RTHQMQLLDALEEA 835
Cdd:TIGR00606  806 RKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKI--ELNRKLIQDQQEQIQHLKsktnelKSEKLQIGTNLQRR 883

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   836 RTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQR-------ENE 908
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIhgymkdiENK 963

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   909 HQARRQEALREQEQELEQAKFEMQErmakqEEKYQNRVNTIEQQYQADFELWKT-EHENKTKLAQAEKENAIRQ--HYRA 985
Cdd:TIGR00606  964 IQDGKDDYLKQKETELNTVNAQLEE-----CEKHQEKINEDMRLMRQDIDTQKIqERWLQDNLTLRKRENELKEveEELK 1038

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   986 ERDRQLDELVVrmeadaLQHKEEHelkmNRLKEkyEKDLVLAESVEKSLREKYAETRGKLAEAD---AQVRNSQAEVKQL 1062
Cdd:TIGR00606 1039 QHLKEMGQMQV------LQMKQEH----QKLEE--NIDLIKRNHVLALGRQKGYEKEIKHFKKElrePQFRDAEEKYREM 1106

                          410       420
                   ....*....|....*....|.
gi 386767627  1063 QLELSHSKKMCGDIIMERDRL 1083
Cdd:TIGR00606 1107 MIVMRTTELVNKDLDIYYKTL 1127

PRK09039

peptidoglycan -binding protein;

798-948

4.00e-03

peptidoglycan -binding protein;

Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 40.72 E-value: 4.00e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  798 TVKGLEAEINKMNcdhqREVTELKrthqmQLLdALEEARTkheqieTSIRESCAQDREAIIEKErtAIRERFERQLEE-- 875
Cdd:PRK09039   47 EISGKDSALDRLN----SQIAELA-----DLL-SLERQGN------QDLQDSVANLRASLSAAE--AERSRLQALLAEla 108

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 386767627  876 EQRTQAEQR-QKLTEEFAAERDRLQSELRQRENEHQarRQEALREQEQELEQAKFEMQERMAKQEEKYQ---NRVNT 948
Cdd:PRK09039  109 GAGAAAEGRaGELAQELDSEKQVSARALAQVELLNQ--QIAALRRQLAALEAALDASEKRDRESQAKIAdlgRRLNV 183

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

698-941

4.30e-03

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.03 E-value: 4.30e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   698 EKQKSLRAEKSTAAAKLRDQKKHYEEVVTRHQGFIEQLLKdkgsLCEKVAALTRRLesqNQAWEHRLETELARTKETTMa 777
Cdd:pfam07888  171 AERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQ----LQDTITTLTQKL---TTAHRKEAENEALLEELRSL- 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   778 gekirRERWVrentkkIKELTVKGLEAEINKMNCDHQREVTELKRTH------QMQLLD---ALEEARTKHEQIETSIRE 848
Cdd:pfam07888  243 -----QERLN------ASERKVEGLGEELSSMAAQRDRTQAELHQARlqaaqlTLQLADaslALREGRARWAQERETLQQ 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   849 SCAQDREAIiEKERTAIrERFERQLEEEQRtqaeQRQKLTEEFAAERD--RLQ-SELRQRENEHQARRQEALREQEQELE 925
Cdd:pfam07888  312 SAEADKDRI-EKLSAEL-QRLEERLQEERM----EREKLEVELGREKDcnRVQlSESRRELQELKASLRVAQKEKEQLQA 385

                          250
                   ....*....|....*.
gi 386767627   926 QaKFEMQERMAKQEEK 941
Cdd:pfam07888  386 E-KQELLEYIRQLEQR 400

PHA02562

endonuclease subunit; Provisional

871-1083

4.66e-03

endonuclease subunit; Provisional

Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.15 E-value: 4.66e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  871 RQLEEEQRTQAEQRQKLTEEFAAERDrLQSELRQRENEHQARRQ---EALREQEQELEQAKFEMQERMA---KQEEKYQN 944
Cdd:PHA02562  177 RELNQQIQTLDMKIDHIQQQIKTYNK-NIEEQRKKNGENIARKQnkyDELVEEAKTIKAEIEELTDELLnlvMDIEDPSA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  945 RVNTIEQ----------QYQADFELWKTEHENKTKLAQ-----------AEKENAIRQHYRAERDRQlDELVVRMEADAL 1003
Cdd:PHA02562  256 ALNKLNTaaakikskieQFQKVIKMYEKGGVCPTCTQQisegpdritkiKDKLKELQHSLEKLDTAI-DELEEIMDEFNE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1004 QHKEEHELKMNRLKEKYEkdlvLAESVEKSLREKYAetrgkLAEADAQVRNSQAEVKQLQLELSHSKKMCGDIIMERDRL 1083
Cdd:PHA02562  335 QSKKLLELKNKISTNKQS----LITLVDKAKKVKAA-----IEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHR 405

COG4372

Uncharacterized protein, contains DUF3084 domain [Function unknown];

827-1005

4.97e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];

Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 40.66 E-value: 4.97e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  827 QLLDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIR-ERFERQLEEEQRTQAEQRQKLtEEFAAERDRLQSELRQR 905
Cdd:COG4372    42 KLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEElEELNEQLQAAQAELAQAQEEL-ESLQEEAEELQEELEEL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  906 ENEHQA--RRQEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFELWKTEHENKTKLAQAEKENAIRQHY 983
Cdd:COG4372   121 QKERQDleQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEE 200

                         170       180
                  ....*....|....*....|..
gi 386767627  984 RAERDRQLDELVVRMEADALQH 1005
Cdd:COG4372   201 ELAEAEKLIESLPRELAEELLE 222

rne

PRK10811

ribonuclease E; Reviewed

866-954

5.26e-03

ribonuclease E; Reviewed

Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 5.26e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  866 RERFERQLEEEQRTQAEQRQKLTEEFAAERDRLQSELRQRENEHQARRQEALREQEQEleqAKFEMQERMAKQEEKYQNR 945
Cdd:PRK10811  636 REENRRNRRQAQQQTAETRESQQAEVTEKARTQDEQQQAPRRERQRRRNDEKRQAQQE---AKALNVEEQSVQETEQEER 712


                  ....*....
gi 386767627  946 VNTIEQQYQ 954
Cdd:PRK10811  713 VQQVQPRRK 721

CusB_dom_1

pfam00529

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...

891-1069

6.08e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.

Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 40.10 E-value: 6.08e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   891 FAAERDRLQSELRQreNEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQnRVNTIEQQYQADFELWKTEHENKTKL 970
Cdd:pfam00529   56 YQAALDSAEAQLAK--AQAQVARLQAELDRLQALESELAISRQDYDGATAQLR-AAQAAVKAAQAQLAQAQIDLARRRVL 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   971 AqaeKENAIRQhyraerdRQLDELvvRMEADALQHkeehelkmNRLKEKYEKDLVLAEsVEKSLREKYAETRGKLAEADA 1050
Cdd:pfam00529  133 A---PIGGISR-------ESLVTA--GALVAQAQA--------NLLATVAQLDQIYVQ-ITQSAAENQAEVRSELSGAQL 191

                          170
                   ....*....|....*....
gi 386767627  1051 QVRNSQAEVKQLQLELSHS 1069
Cdd:pfam00529  192 QIAEAEAELKLAKLDLERT 210

CCCAP

pfam15964

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...

821-1140

6.17e-03

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.

Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 40.66 E-value: 6.17e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   821 KRTHQMQLLDALEEARTKHEQIETSIRESCAQ----DREAIIEKERTAI------------RERFERQLEEEQRTQAEQR 884
Cdd:pfam15964  308 ERDDLMSALVSVRSSLAEAQQRESSAYEQVKQavqmTEEANFEKTKALIqceqlkselerqKERLEKELASQQEKRAQEK 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   885 QKLTEEFAAERDRLQSE---LRQRENEHQARRQEALREQEQELEQAKfEMQERMAKQEEKYQNRVNtiEQQYQAdfelwk 961
Cdd:pfam15964  388 EALRKEMKKEREELGATmlaLSQNVAQLEAQVEKVTREKNSLVSQLE-EAQKQLASQEMDVTKVCG--EMRYQL------ 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   962 teheNKTKLAQAEKENAIRQhYRAERDRQL---DELVVRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSLR--- 1035
Cdd:pfam15964  459 ----NQTKMKKDEAEKEHRE-YRTKTGRQLeikDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLGESEHqlh 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  1036 ----EKYAETRGKLAEADAQVRNSQAEVKQL-----QLELSHSKKmcgdiIMERDRLRDNLN---ADIQSELGVLNERHK 1103
Cdd:pfam15964  534 ltrlEKESIQQSFSNEAKAQALQAQQREQELtqkmqQMEAQHDKT-----VNEQYSLLTSQNtfiAKLKEECCTLAKKLE 608

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 386767627  1104 QEMDQLQKRVHQTIQRQE---ETIEILKGDNDALRQQCLK 1140
Cdd:pfam15964  609 EITQKSRSEVEQLSQEKEylqDRLEKLQKRNEELEEQCVQ 648

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

819-1005

6.21e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 6.21e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  819 ELKRTHQMQLLDA-LEEARTKHEQIETSIREscAQDREAIIEKERTAIRERFE------RQLEEEQRTQAEQRQKLTEEF 891
Cdd:COG1579     5 DLRALLDLQELDSeLDRLEHRLKELPAELAE--LEDELAALEARLEAAKTELEdlekeiKRLELEIEEVEARIKKYEEQL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  892 AAERDRLQSELRQRENEHQARRQEALREQEQELEQAKFEMQERMAKQEEKYQNRvntieqqyQADFELWKTEHEnkTKLA 971
Cdd:COG1579    83 GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAEL--------EAELEEKKAELD--EELA 152

                         170       180       190
                  ....*....|....*....|....*....|....
gi 386767627  972 QAEKEnairqhyRAERDRQLDELVVRMEADALQH 1005
Cdd:COG1579   153 ELEAE-------LEELEAEREELAAKIPPELLAL 179

PRK11281

mechanosensitive channel MscK;

996-1150

6.68e-03

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 40.67 E-value: 6.68e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627  996 VRMEADALQHKEEHELKMNRLKEKYEKDLVLAESVEKSlREKYAETRGKLAEADAQVRNSQAEVKQLqlelshsKKMCGD 1075
Cdd:PRK11281   41 VQAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQ-KEETEQLKQQLAQAPAKLRQAQAELEAL-------KDDNDE 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627 1076 IIMER------DRLRDNLN------ADIQSELGVLN----------ERHKQEMDQLQKRVhQTIQRQEETIEILKGDNDA 1133
Cdd:PRK11281  113 ETRETlstlslRQLESRLAqtldqlQNAQNDLAEYNsqlvslqtqpERAQAALYANSQRL-QQIRNLLKGGKVGGKALRP 191

                         170       180
                  ....*....|....*....|..
gi 386767627 1134 LRQQCLK-----LNAVIRQQRK 1150
Cdd:PRK11281  192 SQRVLLQaeqalLNAQNDLQRK 213

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

685-1122

6.77e-03

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 40.72 E-value: 6.77e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   685 IHMSKEHVFQLRGEKQKSLRAEKSTAAAKLRdqKKHYEEVVTRHQGFIEQLlKDKGSLCEKVAA--------LTRRLESQ 756
Cdd:TIGR00618  427 AHAKKQQELQQRYAELCAAAITCTAQCEKLE--KIHLQESAQSLKEREQQL-QTKEQIHLQETRkkavvlarLLELQEEP 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   757 NQAWEHRLETELARTKETTMAGEKIRRERWvrENTKKIKELTVKGLEAEinkmnCDHQREvtelkrthQMQLLDALEEAR 836
Cdd:TIGR00618  504 CPLCGSCIHPNPARQDIDNPGPLTRRMQRG--EQTYAQLETSEEDVYHQ-----LTSERK--------QRASLKEQMQEI 568

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   837 TKHEQIETSIRESCAQDREaIIEKERTAIRERFERQLEEEQRTQAEQR-QKLTEEFAAERDRLQSELRQRENEHQARRQE 915
Cdd:TIGR00618  569 QQSFSILTQCDNRSKEDIP-NLQNITVRLQDLTEKLSEAEDMLACEQHaLLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   916 ALREQEQELEQAKFEMQERMAKQEEKYQNRVNTIEQQYQADFEL---WKTEHENKTKLAQAEKENA-----IRQHYRAER 987
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQltyWKEMLAQCQTLLRELETHIeeydrEFNEIENAS 727

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   988 DRQLDELVVRMEADALQHKEEHELKMNRLKEKYEKDLV--LAESVEKSLREKYAETRGKLAEADAQVRNSQAEVKQLQLE 1065
Cdd:TIGR00618  728 SSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNnnEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAE 807

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 386767627  1066 LSHSKKMCGDIIMERDRLrdnLNADIQSELGVLNERHKQ--EMDQLQKRVHQTIQRQEE 1122
Cdd:TIGR00618  808 IGQEIPSDEDILNLQCET---LVQEEEQFLSRLEEKSATlgEITHQLLKYEECSKQLAQ 863

Filament

pfam00038

Intermediate filament protein;

796-954

7.15e-03

Intermediate filament protein;

Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 39.90 E-value: 7.15e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   796 ELTVKGLEAEINKMNCDHQREVTELKRTHQMQllDALEEARTKHEQIETSIRESCAQDREAIIEKERTAIRERFERQLEE 875
Cdd:pfam00038  123 EAKIESLKEELAFLKKNHEEEVRELQAQVSDT--QVNVEMDAARKLDLTSALAEIRAQYEEIAAKNREEAEEWYQSKLEE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 386767627   876 EQR---TQAEQRQKLTEEFAAER---DRLQSELrqrenehqarrqEALREQEQELEQAKFEMQERMAKQEEKYQNRVNTI 949
Cdd:pfam00038  201 LQQaaaRNGDALRSAKEEITELRrtiQSLEIEL------------QSLKKQKASLERQLAETEERYELQLADYQELISEL 268


                   ....*
gi 386767627   950 EQQYQ 954
Cdd:pfam00038  269 EAELQ 273

DUF4670