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Conserved domains on  [gi|209977054|ref|NP_001129689|]
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transmembrane protein 51 isoform 1 [Homo sapiens]

Protein Classification

MFS transporter( domain architecture ID 10634019)

major facilitator superfamily (MFS) transporter facilitates the transport across cytoplasmic or internal membranes of one or more from a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TMEM51 pfam15345
Transmembrane protein 51; This family of proteins is found in eukaryotes. Proteins in this ...
7-240 8.84e-105

Transmembrane protein 51; This family of proteins is found in eukaryotes. Proteins in this family are typically between 233 and 253 amino acids in length.


:

Pssm-ID: 464663  Cd Length: 237  Bit Score: 303.18  E-value: 8.84e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054    7 ANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSAAEKPTAQGSNKTE---VGGGILKSKTFSVAYVLVGAGVMLLLLSICL 83
Cdd:pfam15345   1 NSGSHYALTALGVGMLALGIVMIVWNVVPGFGAADKPTASGGNSSKpggDGGGILKSKTSSVAYVLVGAGVALLLLSICL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054   84 SIRDKRKQRQGEDLAHVQHPTGAGPhaqeEDSQEEEEEDEEAASRYYVPSYEEVMNTNYSEARgeEQNPRLSI-SLPSYE 162
Cdd:pfam15345  81 GVRNKRRRRQREEEGARAGPHLQEP----SRSQEEEETAEEDASRYYVPSYEEVVNSGYYPVR--QSNLRPSSsQLPSYE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054  163 SLTGLDETTPT-----STRADVEASPGNPPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRINLPDKNVPPPSIEPLTPPP 237
Cdd:pfam15345 155 SLTGLDENTGTgpaeaPPAAPAEPPPAAPPSRSNSRAGRRLKPLKVRRIKSEKLHLKDFRLNLSQPNQGPVTIEPLTPPP 234

                  ...
gi 209977054  238 QYD 240
Cdd:pfam15345 235 QYE 237
 
Name Accession Description Interval E-value
TMEM51 pfam15345
Transmembrane protein 51; This family of proteins is found in eukaryotes. Proteins in this ...
7-240 8.84e-105

Transmembrane protein 51; This family of proteins is found in eukaryotes. Proteins in this family are typically between 233 and 253 amino acids in length.


Pssm-ID: 464663  Cd Length: 237  Bit Score: 303.18  E-value: 8.84e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054    7 ANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSAAEKPTAQGSNKTE---VGGGILKSKTFSVAYVLVGAGVMLLLLSICL 83
Cdd:pfam15345   1 NSGSHYALTALGVGMLALGIVMIVWNVVPGFGAADKPTASGGNSSKpggDGGGILKSKTSSVAYVLVGAGVALLLLSICL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054   84 SIRDKRKQRQGEDLAHVQHPTGAGPhaqeEDSQEEEEEDEEAASRYYVPSYEEVMNTNYSEARgeEQNPRLSI-SLPSYE 162
Cdd:pfam15345  81 GVRNKRRRRQREEEGARAGPHLQEP----SRSQEEEETAEEDASRYYVPSYEEVVNSGYYPVR--QSNLRPSSsQLPSYE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054  163 SLTGLDETTPT-----STRADVEASPGNPPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRINLPDKNVPPPSIEPLTPPP 237
Cdd:pfam15345 155 SLTGLDENTGTgpaeaPPAAPAEPPPAAPPSRSNSRAGRRLKPLKVRRIKSEKLHLKDFRLNLSQPNQGPVTIEPLTPPP 234

                  ...
gi 209977054  238 QYD 240
Cdd:pfam15345 235 QYE 237
 
Name Accession Description Interval E-value
TMEM51 pfam15345
Transmembrane protein 51; This family of proteins is found in eukaryotes. Proteins in this ...
7-240 8.84e-105

Transmembrane protein 51; This family of proteins is found in eukaryotes. Proteins in this family are typically between 233 and 253 amino acids in length.


Pssm-ID: 464663  Cd Length: 237  Bit Score: 303.18  E-value: 8.84e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054    7 ANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSAAEKPTAQGSNKTE---VGGGILKSKTFSVAYVLVGAGVMLLLLSICL 83
Cdd:pfam15345   1 NSGSHYALTALGVGMLALGIVMIVWNVVPGFGAADKPTASGGNSSKpggDGGGILKSKTSSVAYVLVGAGVALLLLSICL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054   84 SIRDKRKQRQGEDLAHVQHPTGAGPhaqeEDSQEEEEEDEEAASRYYVPSYEEVMNTNYSEARgeEQNPRLSI-SLPSYE 162
Cdd:pfam15345  81 GVRNKRRRRQREEEGARAGPHLQEP----SRSQEEEETAEEDASRYYVPSYEEVVNSGYYPVR--QSNLRPSSsQLPSYE 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209977054  163 SLTGLDETTPT-----STRADVEASPGNPPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRINLPDKNVPPPSIEPLTPPP 237
Cdd:pfam15345 155 SLTGLDENTGTgpaeaPPAAPAEPPPAAPPSRSNSRAGRRLKPLKVRRIKSEKLHLKDFRLNLSQPNQGPVTIEPLTPPP 234

                  ...
gi 209977054  238 QYD 240
Cdd:pfam15345 235 QYE 237
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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