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Conserved domains on  [gi|189181750|ref|NP_001121186|]
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transcription factor HIVEP3 isoform b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
1877-2394 7.42e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 7.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1877 PSSEAPPPGPPHAL-RADSSPILGPQPPDaPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPwlGPAPLGSVEKDtg 1955
Cdd:PHA03247 2551 PPPPLPPAAPPAAPdRSVPPPRPAPRPSE-PAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPP--SPLPPDTHAPD-- 2625
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1956 salsykPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPARepQASAPSPPGLHVDPGRGmgalpcgsPRLQLSP 2035
Cdd:PHA03247 2626 ------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR--RARRLGRAAQASSPPQR--------PRRRAAR 2689
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2036 LTLCPL---------GRELAPRAHVLSklegttdPGLPrySPTRRWSPGQAESPPRSAPPGKWALAGPGSPsAGEHGPgl 2106
Cdd:PHA03247 2690 PTVGSLtsladppppPPTPEPAPHALV-------SATP--LPPGPAAARQASPALPAAPAPPAVPAGPATP-GGPARP-- 2757
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2107 GLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDfhghilarteenifshlPLHSQHL 2186
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA-----------------PAAALPP 2820
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2187 TRAPCPLIPiggiqmvqARPGAHPTLLPGPTAAWVSGFSGGGSDLTGArEAQERG--RWSPTESSSASVSPVAKVSKFTL 2264
Cdd:PHA03247 2821 AASPAGPLP--------PPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG-DVRRRPpsRSPAAKPAAPARPPVRRLARPAV 2891
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2265 SSELEGGDYPKErertggGPGRPPdwTPHgtgAPAEPTPTHSPCTPPDTLPRPPQgrraaqswSPRLESPRAPTNPEPSA 2344
Cdd:PHA03247 2892 SRSTESFALPPD------QPERPP--QPQ---APPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGA 2952
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 189181750 2345 TPPLDRSSSVGCLAEASARFPArTRNLSGEPRTRQDSPKPSGSgEPRAHP 2394
Cdd:PHA03247 2953 GEPSGAVPQPWLGALVPGRVAV-PRFRVPQPAPSREAPASSTP-PLTGHS 3000
zf-H2C2_2 pfam13465
Zinc-finger double domain;
207-231 3.70e-06

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.44  E-value: 3.70e-06
                           10        20
                   ....*....|....*....|....*
gi 189181750   207 LQKHIRSHTGERPYPCGPCGFSFKT 231
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1768-1793 1.25e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 1.25e-05
                           10        20
                   ....*....|....*....|....*.
gi 189181750  1768 MLKKHIRTHTDVRPYVCKHCHFAFKT 1793
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
1754-1776 1.28e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


:

Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.75  E-value: 1.28e-04
                           10        20
                   ....*....|....*....|...
gi 189181750  1754 YVCEECGIRCKKPSMLKKHIRTH 1776
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
1779-1812 9.18e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 9.18e-03
                            10        20        30
                    ....*....|....*....|....*....|....
gi 189181750   1779 VRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQE 1812
Cdd:smart00451    1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKK 34
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
1877-2394 7.42e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 7.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1877 PSSEAPPPGPPHAL-RADSSPILGPQPPDaPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPwlGPAPLGSVEKDtg 1955
Cdd:PHA03247 2551 PPPPLPPAAPPAAPdRSVPPPRPAPRPSE-PAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPP--SPLPPDTHAPD-- 2625
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1956 salsykPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPARepQASAPSPPGLHVDPGRGmgalpcgsPRLQLSP 2035
Cdd:PHA03247 2626 ------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR--RARRLGRAAQASSPPQR--------PRRRAAR 2689
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2036 LTLCPL---------GRELAPRAHVLSklegttdPGLPrySPTRRWSPGQAESPPRSAPPGKWALAGPGSPsAGEHGPgl 2106
Cdd:PHA03247 2690 PTVGSLtsladppppPPTPEPAPHALV-------SATP--LPPGPAAARQASPALPAAPAPPAVPAGPATP-GGPARP-- 2757
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2107 GLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDfhghilarteenifshlPLHSQHL 2186
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA-----------------PAAALPP 2820
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2187 TRAPCPLIPiggiqmvqARPGAHPTLLPGPTAAWVSGFSGGGSDLTGArEAQERG--RWSPTESSSASVSPVAKVSKFTL 2264
Cdd:PHA03247 2821 AASPAGPLP--------PPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG-DVRRRPpsRSPAAKPAAPARPPVRRLARPAV 2891
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2265 SSELEGGDYPKErertggGPGRPPdwTPHgtgAPAEPTPTHSPCTPPDTLPRPPQgrraaqswSPRLESPRAPTNPEPSA 2344
Cdd:PHA03247 2892 SRSTESFALPPD------QPERPP--QPQ---APPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGA 2952
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 189181750 2345 TPPLDRSSSVGCLAEASARFPArTRNLSGEPRTRQDSPKPSGSgEPRAHP 2394
Cdd:PHA03247 2953 GEPSGAVPQPWLGALVPGRVAV-PRFRVPQPAPSREAPASSTP-PLTGHS 3000
zf-H2C2_2 pfam13465
Zinc-finger double domain;
207-231 3.70e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.44  E-value: 3.70e-06
                           10        20
                   ....*....|....*....|....*
gi 189181750   207 LQKHIRSHTGERPYPCGPCGFSFKT 231
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1768-1793 1.25e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 1.25e-05
                           10        20
                   ....*....|....*....|....*.
gi 189181750  1768 MLKKHIRTHTDVRPYVCKHCHFAFKT 1793
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
1754-1776 1.28e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.75  E-value: 1.28e-04
                           10        20
                   ....*....|....*....|...
gi 189181750  1754 YVCEECGIRCKKPSMLKKHIRTH 1776
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
ZnF_C2H2 smart00355
zinc finger;
1754-1776 5.49e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 36.29  E-value: 5.49e-03
                            10        20
                    ....*....|....*....|...
gi 189181750   1754 YVCEECGIRCKKPSMLKKHIRTH 1776
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRTH 23
ZnF_C2H2 smart00355
zinc finger;
1782-1803 6.05e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 36.29  E-value: 6.05e-03
                            10        20
                    ....*....|....*....|..
gi 189181750   1782 YVCKHCHFAFKTKGNLTKHMKS 1803
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRT 22
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
1779-1812 9.18e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 9.18e-03
                            10        20        30
                    ....*....|....*....|....*....|....
gi 189181750   1779 VRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQE 1812
Cdd:smart00451    1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKK 34
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
1877-2394 7.42e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 58.41  E-value: 7.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1877 PSSEAPPPGPPHAL-RADSSPILGPQPPDaPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPwlGPAPLGSVEKDtg 1955
Cdd:PHA03247 2551 PPPPLPPAAPPAAPdRSVPPPRPAPRPSE-PAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPP--SPLPPDTHAPD-- 2625
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1956 salsykPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPARepQASAPSPPGLHVDPGRGmgalpcgsPRLQLSP 2035
Cdd:PHA03247 2626 ------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR--RARRLGRAAQASSPPQR--------PRRRAAR 2689
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2036 LTLCPL---------GRELAPRAHVLSklegttdPGLPrySPTRRWSPGQAESPPRSAPPGKWALAGPGSPsAGEHGPgl 2106
Cdd:PHA03247 2690 PTVGSLtsladppppPPTPEPAPHALV-------SATP--LPPGPAAARQASPALPAAPAPPAVPAGPATP-GGPARP-- 2757
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2107 GLDPRVLFPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRPFSALHDfhghilarteenifshlPLHSQHL 2186
Cdd:PHA03247 2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA-----------------PAAALPP 2820
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2187 TRAPCPLIPiggiqmvqARPGAHPTLLPGPTAAWVSGFSGGGSDLTGArEAQERG--RWSPTESSSASVSPVAKVSKFTL 2264
Cdd:PHA03247 2821 AASPAGPLP--------PPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG-DVRRRPpsRSPAAKPAAPARPPVRRLARPAV 2891
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2265 SSELEGGDYPKErertggGPGRPPdwTPHgtgAPAEPTPTHSPCTPPDTLPRPPQgrraaqswSPRLESPRAPTNPEPSA 2344
Cdd:PHA03247 2892 SRSTESFALPPD------QPERPP--QPQ---APPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGA 2952
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 189181750 2345 TPPLDRSSSVGCLAEASARFPArTRNLSGEPRTRQDSPKPSGSgEPRAHP 2394
Cdd:PHA03247 2953 GEPSGAVPQPWLGALVPGRVAV-PRFRVPQPAPSREAPASSTP-PLTGHS 3000
PHA03247 PHA03247
large tegument protein UL36; Provisional
1979-2403 2.98e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.02  E-value: 2.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1979 PPLARKHSLTKNDSSPQRCSPA---REPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKL 2055
Cdd:PHA03247 2560 PPAAPDRSVPPPRPAPRPSEPAvtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPD 2639
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2056 EGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKwaLAGPGSPSAGEHGPGLgldprvlfPPAPLPHKLLSRSPETCASPW 2135
Cdd:PHA03247 2640 PHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR--AAQASSPPQRPRRRAA--------RPTVGSLTSLADPPPPPPTPE 2709
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2136 KAESRSPSCSPGPAHPLSSRpfsalhdfhghilarteeNIFSHLPLHSQHLTRAPCPLIPIGgiqmvQARPGAHPTLLPG 2215
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAAAR------------------QASPALPAAPAPPAVPAGPATPGG-----PARPARPPTTAGP 2766
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2216 PTAAWVSGFSGGgsdltgareaqergrwsPTESSSASVSPVAKVSKFTLSSELEGGDYPkerertGGGPGRPPDWTPHGT 2295
Cdd:PHA03247 2767 PAPAPPAAPAAG-----------------PPRRLTRPAVASLSESRESLPSPWDPADPP------AAVLAPAAALPPAAS 2823
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2296 GAPAEPTPTHS-PCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGE 2374
Cdd:PHA03247 2824 PAGPLPPPTSAqPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPD 2903
                         410       420
                  ....*....|....*....|....*....
gi 189181750 2375 PRTRQDSPKPSGSGEPRAHPHQPEDRVPP 2403
Cdd:PHA03247 2904 QPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932
zf-H2C2_2 pfam13465
Zinc-finger double domain;
207-231 3.70e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.44  E-value: 3.70e-06
                           10        20
                   ....*....|....*....|....*
gi 189181750   207 LQKHIRSHTGERPYPCGPCGFSFKT 231
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1875-2117 1.14e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1875 SRPSSEAPPPGPPHALRAD----SSPILGPQPPDAPASGTEATRGSSVS-------------EAERLTASSCSMSSQSMP 1937
Cdd:PHA03307  187 SSPPAEPPPSTPPAAASPRpprrSSPISASASSPAPAPGRSAADDAGASssdssssessgcgWGPENECPLPRPAPITLP 266
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1938 GLPWLGPAPL------GSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSP- 2010
Cdd:PHA03307  267 TRIWEASGWNgpssrpGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPs 346
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2011 PGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRS--APPGK 2088
Cdd:PHA03307  347 PSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAgaASGAF 426
                         250       260       270
                  ....*....|....*....|....*....|.
gi 189181750 2089 WALAGPGSPSaGEHGPGLGLDP--RVLFPPA 2117
Cdd:PHA03307  427 YARYPLLTPS-GEPWPGSPPPPpgRVRYGGL 456
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1768-1793 1.25e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 1.25e-05
                           10        20
                   ....*....|....*....|....*.
gi 189181750  1768 MLKKHIRTHTDVRPYVCKHCHFAFKT 1793
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1993-2384 2.88e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.78  E-value: 2.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1993 SPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRL-----QLSPLTLCPLG-RELAPRAHVLSKLEGTTDPGLPRY 2066
Cdd:PHA03307   39 SQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTeapanESRSTPTWSLStLAPASPAREGSPTPPGPSSPDPPP 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2067 SPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASP-WKAESRSPSCS 2145
Cdd:PHA03307  119 PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPsSPPAEPPPSTP 198
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2146 PGPAHPLSSRPFSALHDFHGHI-----------LARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLP 2214
Cdd:PHA03307  199 PAAASPRPPRRSSPISASASSPapapgrsaaddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP 278
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2215 GPTAAWVSGFSGGGSDLTGAREAQERGRWSPT------ESSSASVSPVAKVSKFTLSSELEGGDYPKERERtGGGPGRPP 2288
Cdd:PHA03307  279 SSRPGPASSSSSPRERSPSPSPSSPGSGPAPSsprassSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSR-SPSPSRPP 357
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2289 DWTPhGTGAPAEPTPTHSPCTPPDTLPRPPqgRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSvgclAEASARFPART 2368
Cdd:PHA03307  358 PPAD-PSSPRKRPRPSRAPSSPAASAGRPT--RRRARAAVAGRARRRDATGRFPAGRPRPSPLDA----GAASGAFYARY 430
                         410
                  ....*....|....*...
gi 189181750 2369 RNL--SGEPRTRQDSPKP 2384
Cdd:PHA03307  431 PLLtpSGEPWPGSPPPPP 448
PHA03247 PHA03247
large tegument protein UL36; Provisional
1883-2160 6.75e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 6.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1883 PPGPPHALRADSSPILGPQPPdAPASGTEATRGSSVSEAERLTASSCSMSSQSMP--GLPWLGPAPLGSVEKDTGSALSY 1960
Cdd:PHA03247 2722 PPGPAAARQASPALPAAPAPP-AVPAGPATPGGPARPARPPTTAGPPAPAPPAAPaaGPPRRLTRPAVASLSESRESLPS 2800
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1961 KPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPS-PPGLHVDPG---------RGMGALPCGSPR 2030
Cdd:PHA03247 2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlPLGGSVAPGgdvrrrppsRSPAAKPAAPAR 2880
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2031 LQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKwalagPGSPSAGEHGPGLGLDP 2110
Cdd:PHA03247 2881 PPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR-----PQPPLAPTTDPAGAGEP 2955
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 189181750 2111 RVLFPPAPLPHKLLSRSPET-CASPWKAESRSPSCSpgPAHPLSSRPFSAL 2160
Cdd:PHA03247 2956 SGAVPQPWLGALVPGRVAVPrFRVPQPAPSREAPAS--STPPLTGHSLSRV 3004
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
1754-1776 1.28e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 40.75  E-value: 1.28e-04
                           10        20
                   ....*....|....*....|...
gi 189181750  1754 YVCEECGIRCKKPSMLKKHIRTH 1776
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
2275-2403 2.10e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 2.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2275 KERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPP-------QGRRAAQSWSPRLESPRAPTNPEPSATPP 2347
Cdd:PRK12323  437 RQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAParaapaaAPAPADDDPPPWEELPPEFASPAPAQPDA 516
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 189181750 2348 LDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQP---EDRVPP 2403
Cdd:PRK12323  517 APAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPrasASGLPD 575
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
1876-2156 2.33e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 46.70  E-value: 2.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1876 RPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTG 1955
Cdd:PHA03307   91 SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSR 170
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1956 SALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTknDSSPQRCSPAREPQASAPSPPGLHVDPGRG---MGALPCGSPRLQ 2032
Cdd:PHA03307  171 QAALPLSSPEETARAPSSPPAEPPPSTPPAAAS--PRPPRRSSPISASASSPAPAPGRSAADDAGassSDSSSSESSGCG 248
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2033 LSPLTLCPLGRE------LAPRAHVLSKLEGTT-------DPGLPRYSPTRRWSPGQAESPPRSAPPGKWA------LAG 2093
Cdd:PHA03307  249 WGPENECPLPRPapitlpTRIWEASGWNGPSSRpgpasssSSPRERSPSPSPSSPGSGPAPSSPRASSSSSssressSSS 328
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 189181750 2094 PGSPSAGEHGPGLGLDPrvlfPPAPLPHKLLSRSPETCASPWKAESRSPSCSPGPAHPLSSRP 2156
Cdd:PHA03307  329 TSSSSESSRGAAVSPGP----SPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTR 387
PHA03247 PHA03247
large tegument protein UL36; Provisional
2041-2403 3.87e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 3.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2041 LGRELAPRAHVLSKLEGTTDPGLPRY--SPTRRW--SPGQAESPPRSAPPGKWALAGPGSPSAG---EHGPGLGLDPRVL 2113
Cdd:PHA03247 2455 FARTILGAPFSLSLLLGELFPGAPVYrrPAEARFpfAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpDEPVGEPVHPRML 2534
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2114 F---------------PPAPLPHKLLSRSPETCASPwkaesrsPSCSPGPAHP-LSSRpfsalhdfhghilarteenifS 2177
Cdd:PHA03247 2535 TwirgleelasddagdPPPPLPPAAPPAAPDRSVPP-------PRPAPRPSEPaVTSR---------------------A 2586
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2178 HLPLHSQHLTRAPCPLIPIG---GIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVS 2254
Cdd:PHA03247 2587 RRPDAPPQSARPRAPVDDRGdprGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRR 2666
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2255 PVAKVSKFTLSSELEGGDYPKERERTGG--------GPGRPPDWTPHGTgAPAEPTPT-------HSPCTPPDTLPRPP- 2318
Cdd:PHA03247 2667 ARRLGRAAQASSPPQRPRRRAARPTVGSltsladppPPPPTPEPAPHAL-VSATPLPPgpaaarqASPALPAAPAPPAVp 2745
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2319 -----------QGRRAAQSWSPRLESPRAP-TNPEPSATPPLDRSSSVGCLAEASARFPA------RTRNLSGEPRTRQD 2380
Cdd:PHA03247 2746 agpatpggparPARPPTTAGPPAPAPPAAPaAGPPRRLTRPAVASLSESRESLPSPWDPAdppaavLAPAAALPPAASPA 2825
                         410       420
                  ....*....|....*....|...
gi 189181750 2381 SPKPSGSGEPRAHPHQPEDRVPP 2403
Cdd:PHA03247 2826 GPLPPPTSAQPTAPPPPPGPPPP 2848
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
1782-1803 3.87e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.59  E-value: 3.87e-04
                           10        20
                   ....*....|....*....|..
gi 189181750  1782 YVCKHCHFAFKTKGNLTKHMKS 1803
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRT 22
PHA03247 PHA03247
large tegument protein UL36; Provisional
1877-2160 9.02e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 9.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1877 PSSEAPP--PGPPHALRADSSPILgPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDT 1954
Cdd:PHA03247 2775 PAAGPPRrlTRPAVASLSESRESL-PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1955 GSALSYKPVS---PRRPWSPSKEAGSRPP---LARKHSLTKNDSSPQ-RCSPAREPQASAPSPP----GLHVDPGRGMGA 2023
Cdd:PHA03247 2854 GSVAPGGDVRrrpPSRSPAAKPAAPARPPvrrLARPAVSRSTESFALpPDQPERPPQPQAPPPPqpqpQPPPPPQPQPPP 2933
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2024 LPCGSPRLQLSPLTLCPLGRElaPRAHVLSKLEGTTDPGlpRYSPTRRWSPGQAESPPRSAPPGKwALAGPGSPSAGEHG 2103
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGE--PSGAVPQPWLGALVPG--RVAVPRFRVPQPAPSREAPASSTP-PLTGHSLSRVSSWA 3008
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 189181750 2104 PGLGLDPRVLFPPAPLPHKLLSRSPETCAS--------PWKAESRSPSCSPGPAH-PLSSRPFSAL 2160
Cdd:PHA03247 3009 SSLALHEETDPPPVSLKQTLWPPDDTEDSDadslfdsdSERSDLEALDPLPPEPHdPFAHEPDPAT 3074
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1880-2099 1.94e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 1.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1880 EAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTG-SAL 1958
Cdd:PRK12323  371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGaPAP 450
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 1959 SYKPVSPRRPWSPSKEAGSRPPLArkhsltKNDSSPQRCSPAREPQASAPSPPGLHVDPgrgmGALPCGSPRlqlspltl 2038
Cdd:PRK12323  451 APAPAAAPAAAARPAAAGPRPVAA------AAAAAPARAAPAAAPAPADDDPPPWEELP----PEFASPAPA-------- 512
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 189181750 2039 cPLGRELAPRAHVLSKLEGTTDPGLPRysPTRRWSPGQAESPPRSAPPGKWALAGPGSPSA 2099
Cdd:PRK12323  513 -QPDAAPAGWVAESIPDPATADPDDAF--ETLAPAPAAAPAPRAAAATEPVVAPRPPRASA 570
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2276-2405 4.71e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 4.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2276 ERERTGGGPGRPPDwTPHGTGAPAEPTPTHSPCTPPdtlpRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPlDRSSSVG 2355
Cdd:PRK07764  382 ERRLGVAGGAGAPA-AAAPSAAAAAPAAAPAPAAAA----PAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNA-PAGGAPS 455
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 189181750 2356 CLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA 2405
Cdd:PRK07764  456 PPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAG 505
ZnF_C2H2 smart00355
zinc finger;
1754-1776 5.49e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 36.29  E-value: 5.49e-03
                            10        20
                    ....*....|....*....|...
gi 189181750   1754 YVCEECGIRCKKPSMLKKHIRTH 1776
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRTH 23
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
2277-2403 5.90e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 5.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2277 RERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGC 2356
Cdd:PHA03307  102 REGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE 181
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 189181750 2357 LAEASARfPARTRNLSGEPRTRQDSPKPSGSgePRAHPHQPEDRVPP 2403
Cdd:PHA03307  182 TARAPSS-PPAEPPPSTPPAAASPRPPRRSS--PISASASSPAPAPG 225
ZnF_C2H2 smart00355
zinc finger;
1782-1803 6.05e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 36.29  E-value: 6.05e-03
                            10        20
                    ....*....|....*....|..
gi 189181750   1782 YVCKHCHFAFKTKGNLTKHMKS 1803
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRT 22
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
2280-2403 6.29e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 6.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 189181750 2280 TGGGPGRPPDwtPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQ------SWSPRLESPRAPTNPEPSATPPLDRSSS 2353
Cdd:PRK07764  617 APAAPAAPAA--PAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPdasdggDGWPAKAGGAAPAAPPPAPAPAAPAAPA 694
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 189181750 2354 VGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPrahPHQPEDRVPP 2403
Cdd:PRK07764  695 GAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAP---SPAADDPVPL 741
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
1779-1812 9.18e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 35.69  E-value: 9.18e-03
                            10        20        30
                    ....*....|....*....|....*....|....
gi 189181750   1779 VRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQE 1812
Cdd:smart00451    1 TGGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKK 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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