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Conserved domains on  [gi|186505715|ref|NP_001118448|]
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Putative lysine decarboxylase family protein [Arabidopsis thaliana]

Protein Classification

LOG family protein( domain architecture ID 10508359)

LOG (Lonely Guy) family protein similar to Arabidopsis thaliana cytokinin riboside 5'-monophosphate phosphoribohydrolases, which are cytokinin-activating enzymes working in the direct activation pathway, converting inactive cytokinin nucleotides to the biologically active free-base forms

CATH:  3.40.50.450
EC:  3.2.2.-
Gene Ontology:  GO:0016799|GO:0009691
PubMed:  28374778|29525484
SCOP:  4001074

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lysine_decarbox pfam03641
Possible lysine decarboxylase; The members of this family share a highly conserved motif ...
 1-130 2.96e-62

Possible lysine decarboxylase; The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.


:

Pssm-ID: 397621  Cd Length: 130  Bit Score: 187.81  E-value: 2.96e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715    1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:pfam03641   1 MGAVADGALEAGGRVIGIIPKILLPEEIPNPIVTELIIVPDMHERKAAMAELADAFVALPGGFGTLEELFEILTWIQLGI 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 186505715   81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQL 130
Cdd:pfam03641  81 HQKPIVLLNPDGYYDPLLEFIDHMVDEGFISPEARELIIVVDDPEELLEK 130
 
Name Accession Description Interval E-value
Lysine_decarbox pfam03641
Possible lysine decarboxylase; The members of this family share a highly conserved motif ...
 1-130 2.96e-62

Possible lysine decarboxylase; The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.


Pssm-ID: 397621  Cd Length: 130  Bit Score: 187.81  E-value: 2.96e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715    1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:pfam03641   1 MGAVADGALEAGGRVIGIIPKILLPEEIPNPIVTELIIVPDMHERKAAMAELADAFVALPGGFGTLEELFEILTWIQLGI 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 186505715   81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQL 130
Cdd:pfam03641  81 HQKPIVLLNPDGYYDPLLEFIDHMVDEGFISPEARELIIVVDDPEELLEK 130
PpnN COG1611
Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport ...
 1-140 1.57e-56

Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport and metabolism];


Pssm-ID: 441219  Cd Length: 184  Bit Score: 174.91  E-value: 1.57e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715   1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:COG1611   44 MGAVADGALEAGGRSIGVIPHFLVEREVANPYLTELIVVDYMHERKAMMLELADAFVALPGGFGTLDELFEVLTLAQLGK 123

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715  81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQLLEEYVPKHDD 140
Cdd:COG1611  124 HPKPIVLLNGNGFWDPLLDWLDHMLEEGFISPEDLDLLLVVDDPEEALDALEAYEPPYAS 183
TIGR00730 TIGR00730
TIGR00730 family protein; This model represents one branch of a subfamily of proteins of ...
 1-134 8.69e-44

TIGR00730 family protein; This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved]


Pssm-ID: 129813 [Multi-domain]  Cd Length: 178  Bit Score: 142.65  E-value: 8.69e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715    1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:TIGR00730  45 MGAIADAAMENGGTAVGVNPSGLFSGEVVHQNLTELIEVNGMHERKAMMAELADAFIAMPGGFGTLEELFEVLTWAQLGI 124

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 186505715   81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQLLEEY 134
Cdd:TIGR00730 125 HQKPIILFNVNGHFDGLVEWLKYSIQEGFISESHLKLIHVVSRPDELIEQVQNY 178
 
Name Accession Description Interval E-value
Lysine_decarbox pfam03641
Possible lysine decarboxylase; The members of this family share a highly conserved motif ...
 1-130 2.96e-62

Possible lysine decarboxylase; The members of this family share a highly conserved motif PGGXGTXXE that is probably functionally important. This family includes proteins annotated as lysine decarboxylases, although the evidence for this is not clear.


Pssm-ID: 397621  Cd Length: 130  Bit Score: 187.81  E-value: 2.96e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715    1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:pfam03641   1 MGAVADGALEAGGRVIGIIPKILLPEEIPNPIVTELIIVPDMHERKAAMAELADAFVALPGGFGTLEELFEILTWIQLGI 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 186505715   81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQL 130
Cdd:pfam03641  81 HQKPIVLLNPDGYYDPLLEFIDHMVDEGFISPEARELIIVVDDPEELLEK 130
PpnN COG1611
Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport ...
 1-140 1.57e-56

Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family [Nucleotide transport and metabolism];


Pssm-ID: 441219  Cd Length: 184  Bit Score: 174.91  E-value: 1.57e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715   1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:COG1611   44 MGAVADGALEAGGRSIGVIPHFLVEREVANPYLTELIVVDYMHERKAMMLELADAFVALPGGFGTLDELFEVLTLAQLGK 123

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715  81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQLLEEYVPKHDD 140
Cdd:COG1611  124 HPKPIVLLNGNGFWDPLLDWLDHMLEEGFISPEDLDLLLVVDDPEEALDALEAYEPPYAS 183
TIGR00730 TIGR00730
TIGR00730 family protein; This model represents one branch of a subfamily of proteins of ...
 1-134 8.69e-44

TIGR00730 family protein; This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved]


Pssm-ID: 129813 [Multi-domain]  Cd Length: 178  Bit Score: 142.65  E-value: 8.69e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 186505715    1 MGLISQAVHDGGRHVLGIIPKSLAPREITGESIGEVITVSTMHQRKAEMGRQADAFIALPGGYGTFEELLEVITWSQLGI 80
Cdd:TIGR00730  45 MGAIADAAMENGGTAVGVNPSGLFSGEVVHQNLTELIEVNGMHERKAMMAELADAFIAMPGGFGTLEELFEVLTWAQLGI 124

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 186505715   81 HTKPVGLLNVDGFYDSLLTFIDKAVDEGFVSSTARRIIVSAPNAPQLLQLLEEY 134
Cdd:TIGR00730 125 HQKPIILFNVNGHFDGLVEWLKYSIQEGFISESHLKLIHVVSRPDELIEQVQNY 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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