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Conserved domains on  [gi|169259762|ref|NP_001108558|]
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protein mono-ADP-ribosyltransferase PARP12b [Danio rerio]

Protein Classification

WWE domain-containing protein( domain architecture ID 10251524)

WWE domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WWE pfam02825
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
 357-425 1.12e-09

WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.


:

Pssm-ID: 460715 [Multi-domain]  Cd Length: 66  Bit Score: 54.22  E-value: 1.12e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169259762  357 IWYYKGDHENWIEYGHPDdkqratsvtSRELEKSFQEDN-NAEVTVIKGNRHYYVSFQDMYQRNPKHNTK 425
Cdd:pfam02825   1 VWEWEDDNGGWHPYDPEV---------SSLIEEAYQKGKpSVDLSITTAGFPYTIDFKSMTQTNKDTGTT 61
WWE super family cl46925
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
 286-349 2.46e-04

Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;


The actual alignment was detected with superfamily member smart00678:

Pssm-ID: 128922 [Multi-domain]  Cd Length: 73  Bit Score: 39.25  E-value: 2.46e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169259762   286 YKWELYDGKG-WREL--RNMEDIERAYC--DPKNEYSPGSRP--VNFVSMTKNGDPVRRLSTVSSVSKPAH 349
Cdd:smart00678   1 YVWEYEGRNGkWWPYdpRVSEDIEEAYAagKKLCELSICGFPytIDFNAMTQYNQATGTTRKVRRVTYSPY 71
 
Name Accession Description Interval E-value
WWE pfam02825
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
 357-425 1.12e-09

WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.


Pssm-ID: 460715 [Multi-domain]  Cd Length: 66  Bit Score: 54.22  E-value: 1.12e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169259762  357 IWYYKGDHENWIEYGHPDdkqratsvtSRELEKSFQEDN-NAEVTVIKGNRHYYVSFQDMYQRNPKHNTK 425
Cdd:pfam02825   1 VWEWEDDNGGWHPYDPEV---------SSLIEEAYQKGKpSVDLSITTAGFPYTIDFKSMTQTNKDTGTT 61
WWE smart00678
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
 286-349 2.46e-04

Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;


Pssm-ID: 128922 [Multi-domain]  Cd Length: 73  Bit Score: 39.25  E-value: 2.46e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169259762   286 YKWELYDGKG-WREL--RNMEDIERAYC--DPKNEYSPGSRP--VNFVSMTKNGDPVRRLSTVSSVSKPAH 349
Cdd:smart00678   1 YVWEYEGRNGkWWPYdpRVSEDIEEAYAagKKLCELSICGFPytIDFNAMTQYNQATGTTRKVRRVTYSPY 71
WWE smart00678
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
 356-428 8.20e-03

Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;


Pssm-ID: 128922 [Multi-domain]  Cd Length: 73  Bit Score: 35.01  E-value: 8.20e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 169259762   356 WIWYYKGDHENWIEYghpddkqraTSVTSRELEKSFQEDNNAEVTVIKGNRhYYVSFQDMYQRNPKHNTKRRV 428
Cdd:smart00678   1 YVWEYEGRNGKWWPY---------DPRVSEDIEEAYAAGKKLCELSICGFP-YTIDFNAMTQYNQATGTTRKV 63
 
Name Accession Description Interval E-value
WWE pfam02825
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
 357-425 1.12e-09

WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.


Pssm-ID: 460715 [Multi-domain]  Cd Length: 66  Bit Score: 54.22  E-value: 1.12e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 169259762  357 IWYYKGDHENWIEYGHPDdkqratsvtSRELEKSFQEDN-NAEVTVIKGNRHYYVSFQDMYQRNPKHNTK 425
Cdd:pfam02825   1 VWEWEDDNGGWHPYDPEV---------SSLIEEAYQKGKpSVDLSITTAGFPYTIDFKSMTQTNKDTGTT 61
WWE smart00678
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
 286-349 2.46e-04

Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;


Pssm-ID: 128922 [Multi-domain]  Cd Length: 73  Bit Score: 39.25  E-value: 2.46e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 169259762   286 YKWELYDGKG-WREL--RNMEDIERAYC--DPKNEYSPGSRP--VNFVSMTKNGDPVRRLSTVSSVSKPAH 349
Cdd:smart00678   1 YVWEYEGRNGkWWPYdpRVSEDIEEAYAagKKLCELSICGFPytIDFNAMTQYNQATGTTRKVRRVTYSPY 71
WWE smart00678
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
 356-428 8.20e-03

Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;


Pssm-ID: 128922 [Multi-domain]  Cd Length: 73  Bit Score: 35.01  E-value: 8.20e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 169259762   356 WIWYYKGDHENWIEYghpddkqraTSVTSRELEKSFQEDNNAEVTVIKGNRhYYVSFQDMYQRNPKHNTKRRV 428
Cdd:smart00678   1 YVWEYEGRNGKWWPY---------DPRVSEDIEEAYAAGKKLCELSICGFP-YTIDFNAMTQYNQATGTTRKV 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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