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Conserved domains on  [gi|161076122|ref|NP_001104426|]
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uncharacterized protein Dmel_CG40228, isoform C [Drosophila melanogaster]

Protein Classification

transcription elongation factor 1 family protein( domain architecture ID 10523973)

transcription elongation factor 1 (ELOF1) family protein may be a transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions

Gene Ontology:  GO:0046872|GO:0008023|GO:0006368
PubMed:  16260625

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Elf1 pfam05129
Transcription elongation factor Elf1 like; This family of short proteins contains a putative ...
 2-79 3.66e-38

Transcription elongation factor Elf1 like; This family of short proteins contains a putative zinc binding domain with four conserved cysteines. Swiss:P36053 has been identified as a transcription elongation factor in Saccharomyces cerevisiae.


:

Pssm-ID: 461556  Cd Length: 77  Bit Score: 121.51  E-value: 3.66e-38
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161076122   2 GRRKSKRKPPPKRKniEPLDQQFNCPFCNHEKSCEVKMDKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDACE 79
Cdd:pfam05129  1 GKRKKKPKKKKKKK--PKLPTVFTCPFCNHEKSVSVKIDKKDGIAILSCGVCGLSFQTEINPLSEPVDVYSDWIDACE 76
 
Name Accession Description Interval E-value
Elf1 pfam05129
Transcription elongation factor Elf1 like; This family of short proteins contains a putative ...
 2-79 3.66e-38

Transcription elongation factor Elf1 like; This family of short proteins contains a putative zinc binding domain with four conserved cysteines. Swiss:P36053 has been identified as a transcription elongation factor in Saccharomyces cerevisiae.


Pssm-ID: 461556  Cd Length: 77  Bit Score: 121.51  E-value: 3.66e-38
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161076122   2 GRRKSKRKPPPKRKniEPLDQQFNCPFCNHEKSCEVKMDKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDACE 79
Cdd:pfam05129  1 GKRKKKPKKKKKKK--PKLPTVFTCPFCNHEKSVSVKIDKKDGIAILSCGVCGLSFQTEINPLSEPVDVYSDWIDACE 76
PRK14892 PRK14892
putative transcription elongation factor Elf1; Provisional
 1-77 1.99e-08

putative transcription elongation factor Elf1; Provisional


Pssm-ID: 184886  Cd Length: 99  Bit Score: 46.97  E-value: 1.99e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 161076122  1 MGRRKSKRKPPPKRKNIEPldQQFNCPFCNhEKSCEVKmdKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDA 77
Cdd:PRK14892  1 MGRRRKKRKKIIRPKPKLP--KIFECPRCG-KVSISVK--IKKNIAIITCGNCGLYTEFEVPSVYDEVDVYNKFIDL 72
 
Name Accession Description Interval E-value
Elf1 pfam05129
Transcription elongation factor Elf1 like; This family of short proteins contains a putative ...
 2-79 3.66e-38

Transcription elongation factor Elf1 like; This family of short proteins contains a putative zinc binding domain with four conserved cysteines. Swiss:P36053 has been identified as a transcription elongation factor in Saccharomyces cerevisiae.


Pssm-ID: 461556  Cd Length: 77  Bit Score: 121.51  E-value: 3.66e-38
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161076122   2 GRRKSKRKPPPKRKniEPLDQQFNCPFCNHEKSCEVKMDKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDACE 79
Cdd:pfam05129  1 GKRKKKPKKKKKKK--PKLPTVFTCPFCNHEKSVSVKIDKKDGIAILSCGVCGLSFQTEINPLSEPVDVYSDWIDACE 76
PRK14892 PRK14892
putative transcription elongation factor Elf1; Provisional
 1-77 1.99e-08

putative transcription elongation factor Elf1; Provisional


Pssm-ID: 184886  Cd Length: 99  Bit Score: 46.97  E-value: 1.99e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 161076122  1 MGRRKSKRKPPPKRKNIEPldQQFNCPFCNhEKSCEVKmdKSRNTAKITCRVCLEDFQTGINFLSEPIDVYNDWVDA 77
Cdd:PRK14892  1 MGRRRKKRKKIIRPKPKLP--KIFECPRCG-KVSISVK--IKKNIAIITCGNCGLYTEFEVPSVYDEVDVYNKFIDL 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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