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Conserved domains on  [gi|157819057|ref|NP_001103060|]
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uncharacterized protein LOC690415 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
23-63 1.64e-08

Keratin, high sulfur B2 protein;


:

Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 49.30  E-value: 1.64e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157819057   23 CPESCCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPC 63
Cdd:pfam13885   2 CQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCC 42
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 23-160 3.70e-08

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 51.33  E-value: 3.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157819057   23 CPESCCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPCLLCTPVscvsspccqssCCTPSCCQQSSCQPACCTSSPC 102
Cdd:pfam01500  20 CGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQTS-----------CCQPTCCQTSSCQTGCGGIGYG 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157819057  103 QQPCGVTLCCKPVCCTPICSGSSSCCQQSSCQSSCCQPSCCVTL----CCRPVCCKPVCCTP 160
Cdd:pfam01500  89 QEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHaqasCCRPSYCGQSCCRP 150
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
199-239 3.79e-03

Keratin, high sulfur B2 protein;


:

Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 34.28  E-value: 3.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157819057  199 CRPACCVPtSSCCASSCQPSCCRPASCVSLLCRPACSCTTC 239
Cdd:pfam13885   2 CQPSCCQP-SCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSC 41
 
Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
23-63 1.64e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 49.30  E-value: 1.64e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157819057   23 CPESCCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPC 63
Cdd:pfam13885   2 CQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCC 42
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 23-160 3.70e-08

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 51.33  E-value: 3.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157819057   23 CPESCCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPCLLCTPVscvsspccqssCCTPSCCQQSSCQPACCTSSPC 102
Cdd:pfam01500  20 CGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQTS-----------CCQPTCCQTSSCQTGCGGIGYG 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157819057  103 QQPCGVTLCCKPVCCTPICSGSSSCCQQSSCQSSCCQPSCCVTL----CCRPVCCKPVCCTP 160
Cdd:pfam01500  89 QEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHaqasCCRPSYCGQSCCRP 150
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
199-239 3.79e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 34.28  E-value: 3.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157819057  199 CRPACCVPtSSCCASSCQPSCCRPASCVSLLCRPACSCTTC 239
Cdd:pfam13885   2 CQPSCCQP-SCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSC 41
 
Name Accession Description Interval E-value
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
23-63 1.64e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 49.30  E-value: 1.64e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157819057   23 CPESCCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPC 63
Cdd:pfam13885   2 CQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCC 42
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
27-63 2.88e-08

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 48.53  E-value: 2.88e-08
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 157819057   27 CCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPC 63
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCC 37
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 23-160 3.70e-08

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 51.33  E-value: 3.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157819057   23 CPESCCEPCGCAPSCCQPSCCVPSCCQSSCCAPSCCAPTPCLLCTPVscvsspccqssCCTPSCCQQSSCQPACCTSSPC 102
Cdd:pfam01500  20 CGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQTS-----------CCQPTCCQTSSCQTGCGGIGYG 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157819057  103 QQPCGVTLCCKPVCCTPICSGSSSCCQQSSCQSSCCQPSCCVTL----CCRPVCCKPVCCTP 160
Cdd:pfam01500  89 QEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHaqasCCRPSYCGQSCCRP 150
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 84-239 2.34e-07

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 49.02  E-value: 2.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157819057   84 PSCCQQSSCQPACCTSSPCQQPCGVTLCCKPVCCTPICsgsssccqqsscqssccqpsccvTLCCRPVCCKPVCCtpICS 163
Cdd:pfam01500  27 PCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPCCQ-----------------------TSCCQPTCCQTSSC--QTG 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157819057  164 ASSSSCCQPSCCAPVCCKPVCCKPCSSLSLLCSPVCRPACCVPTSSCCASSCQPSCCRPASCVSLLCRPACSCTTC 239
Cdd:pfam01500  82 CGGIGYGQEGSSGAVSSRTRWCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCS 157
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
37-103 1.04e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 41.60  E-value: 1.04e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157819057   37 CCQPSCCVPSCCQSSCCAPSCCaptpcllctpvscvsspccqssccTPSCCQQSSCQPACCTSSPCQ 103
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCC------------------------QPSCCQPSCCRPSCCRSSCCQ 43
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
83-120 3.33e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 40.06  E-value: 3.33e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 157819057   83 TPSCCQQSSCQPACCTSSPCQQPCGVTLCCKPVCCTPI 120
Cdd:pfam13885   8 QPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
199-239 3.79e-03

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 34.28  E-value: 3.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157819057  199 CRPACCVPtSSCCASSCQPSCCRPASCVSLLCRPACSCTTC 239
Cdd:pfam13885   2 CQPSCCQP-SCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSC 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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