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Conserved domains on  [gi|157823787|ref|NP_001102967|]
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putative nucleotidyltransferase MAB21L1 [Rattus norvegicus]

Protein Classification

Mab-21 family protein( domain architecture ID 10505530)

Mab-21 family protein, similar to Caenorhabditis elegans Mab-21 (Protein male abnormal 21) which acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
 62-241 1.47e-47

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


:

Pssm-ID: 460873  Cd Length: 191  Bit Score: 159.51  E-value: 1.47e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787   62 RYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSlPGCAVLKLSD---------GRKRSMSLWVEFiTASGYLSARKIRSRF 132
Cdd:pfam03281   1 YYENLKVLSPDEFDVMLPLRGPMNDLIIVMGV-PGYVVLKLTRwryylhnpvGRPESLSQWLEF-TAEGYLSAAKVLSRF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787  133 QTLVAQAVDKC---SYRDVVKMVADTSEVKLRI---RDRYVVQITPAFKCTGIWPRSaAHWPLPHIPWPGPNRVAEVKAE 206
Cdd:pfam03281  79 QSLVEKALNTVndsIYGLVYKREKGGPAVTLAIetsEDQYSVDLVPAIECPGIWPKS-ARWPRCLKRWPSQKVLRKIKSE 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 157823787  207 GFNLLSKEchslAGKQSSAESDAWVLQFAEAENRL 241
Cdd:pfam03281 158 GFHLVAKS----SPWPSSDENYSWRLSFSQAEKVL 188
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 246-344 3.68e-35

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


:

Pssm-ID: 466416  Cd Length: 102  Bit Score: 124.27  E-value: 3.68e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787  246 CRKKCLSILKTLRD---RHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLP 322
Cdd:pfam20266   1 CRKKCLRILKKLKEpgkRDVKTELSKICSYHLKTLFLWECEKHPDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHFFIP 80

                          90       100
                  ....*....|....*....|..
gi 157823787  323 NLDLFQGKPHSALENAAKQTWR 344
Cdd:pfam20266  81 KLNLFQSLSRKELDDLAKKLED 102
 
Name Accession Description Interval E-value
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
 62-241 1.47e-47

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 460873  Cd Length: 191  Bit Score: 159.51  E-value: 1.47e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787   62 RYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSlPGCAVLKLSD---------GRKRSMSLWVEFiTASGYLSARKIRSRF 132
Cdd:pfam03281   1 YYENLKVLSPDEFDVMLPLRGPMNDLIIVMGV-PGYVVLKLTRwryylhnpvGRPESLSQWLEF-TAEGYLSAAKVLSRF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787  133 QTLVAQAVDKC---SYRDVVKMVADTSEVKLRI---RDRYVVQITPAFKCTGIWPRSaAHWPLPHIPWPGPNRVAEVKAE 206
Cdd:pfam03281  79 QSLVEKALNTVndsIYGLVYKREKGGPAVTLAIetsEDQYSVDLVPAIECPGIWPKS-ARWPRCLKRWPSQKVLRKIKSE 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 157823787  207 GFNLLSKEchslAGKQSSAESDAWVLQFAEAENRL 241
Cdd:pfam03281 158 GFHLVAKS----SPWPSSDENYSWRLSFSQAEKVL 188
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 246-344 3.68e-35

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 124.27  E-value: 3.68e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787  246 CRKKCLSILKTLRD---RHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLP 322
Cdd:pfam20266   1 CRKKCLRILKKLKEpgkRDVKTELSKICSYHLKTLFLWECEKHPDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHFFIP 80

                          90       100
                  ....*....|....*....|..
gi 157823787  323 NLDLFQGKPHSALENAAKQTWR 344
Cdd:pfam20266  81 KLNLFQSLSRKELDDLAKKLED 102
 
Name Accession Description Interval E-value
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
 62-241 1.47e-47

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 460873  Cd Length: 191  Bit Score: 159.51  E-value: 1.47e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787   62 RYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSlPGCAVLKLSD---------GRKRSMSLWVEFiTASGYLSARKIRSRF 132
Cdd:pfam03281   1 YYENLKVLSPDEFDVMLPLRGPMNDLIIVMGV-PGYVVLKLTRwryylhnpvGRPESLSQWLEF-TAEGYLSAAKVLSRF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787  133 QTLVAQAVDKC---SYRDVVKMVADTSEVKLRI---RDRYVVQITPAFKCTGIWPRSaAHWPLPHIPWPGPNRVAEVKAE 206
Cdd:pfam03281  79 QSLVEKALNTVndsIYGLVYKREKGGPAVTLAIetsEDQYSVDLVPAIECPGIWPKS-ARWPRCLKRWPSQKVLRKIKSE 157

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 157823787  207 GFNLLSKEchslAGKQSSAESDAWVLQFAEAENRL 241
Cdd:pfam03281 158 GFHLVAKS----SPWPSSDENYSWRLSFSQAEKVL 188
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 246-344 3.68e-35

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 124.27  E-value: 3.68e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823787  246 CRKKCLSILKTLRD---RHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLP 322
Cdd:pfam20266   1 CRKKCLRILKKLKEpgkRDVKTELSKICSYHLKTLFLWECEKHPDDSDWDKENLSDRFLGLLEELHKCLRNGKLPHFFIP 80

                          90       100
                  ....*....|....*....|..
gi 157823787  323 NLDLFQGKPHSALENAAKQTWR 344
Cdd:pfam20266  81 KLNLFQSLSRKELDDLAKKLED 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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