NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|157822783|ref|NP_001102689|]
View 

transmembrane protein 243 [Rattus norvegicus]

Protein Classification

TMEM243 family protein( domain architecture ID 10566815)

TMEM243 family protein is a DUF2678 domain-containing protein; similar to Homo sapiens transmembrane protein 243, also known as MDR1- and mitochondrial taxol resistance-associated protein (MM-TRAG), a novel intracellular mitochondrial protein associated with the taxol- and doxorubicin-resistant phenotype in human cancer cell lines

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF2678 pfam10856
Protein of unknown function (DUF2678); This family of proteins has no known function.
 1-118 4.06e-64

Protein of unknown function (DUF2678); This family of proteins has no known function.


:

Pssm-ID: 463191  Cd Length: 118  Bit Score: 190.40  E-value: 4.06e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157822783    1 MEDFATRTYGTSGLDNRPLFGETSAKDRIINLVVGGLTTLLILVTLVSAFLFPQLPPKPLNIFFAVCISLSSITACILIY 80
Cdd:pfam10856   1 MDDFRTRTYGTSGLDNRPLFGETSARDRIINLAVGGLTSLLVLVTVISSFVFPTLPPKPLNIFFAVCILLICSSVLVLIF 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 157822783   81 WYRQGDLEPKFRNLIYYILFSIIMLCICANLYFHDVGR 118
Cdd:pfam10856  81 WYRQGDLEPKFRNLIYYMIGSIILLCLCANLYFHDVGR 118
 
Name Accession Description Interval E-value
DUF2678 pfam10856
Protein of unknown function (DUF2678); This family of proteins has no known function.
 1-118 4.06e-64

Protein of unknown function (DUF2678); This family of proteins has no known function.


Pssm-ID: 463191  Cd Length: 118  Bit Score: 190.40  E-value: 4.06e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157822783    1 MEDFATRTYGTSGLDNRPLFGETSAKDRIINLVVGGLTTLLILVTLVSAFLFPQLPPKPLNIFFAVCISLSSITACILIY 80
Cdd:pfam10856   1 MDDFRTRTYGTSGLDNRPLFGETSARDRIINLAVGGLTSLLVLVTVISSFVFPTLPPKPLNIFFAVCILLICSSVLVLIF 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 157822783   81 WYRQGDLEPKFRNLIYYILFSIIMLCICANLYFHDVGR 118
Cdd:pfam10856  81 WYRQGDLEPKFRNLIYYMIGSIILLCLCANLYFHDVGR 118
 
Name Accession Description Interval E-value
DUF2678 pfam10856
Protein of unknown function (DUF2678); This family of proteins has no known function.
 1-118 4.06e-64

Protein of unknown function (DUF2678); This family of proteins has no known function.


Pssm-ID: 463191  Cd Length: 118  Bit Score: 190.40  E-value: 4.06e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157822783    1 MEDFATRTYGTSGLDNRPLFGETSAKDRIINLVVGGLTTLLILVTLVSAFLFPQLPPKPLNIFFAVCISLSSITACILIY 80
Cdd:pfam10856   1 MDDFRTRTYGTSGLDNRPLFGETSARDRIINLAVGGLTSLLVLVTVISSFVFPTLPPKPLNIFFAVCILLICSSVLVLIF 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 157822783   81 WYRQGDLEPKFRNLIYYILFSIIMLCICANLYFHDVGR 118
Cdd:pfam10856  81 WYRQGDLEPKFRNLIYYMIGSIILLCLCANLYFHDVGR 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH