|
Name |
Accession |
Description |
Interval |
E-value |
| Ubl_RB1CC1 |
cd17060 |
ubiquitin-like (Ubl) domain found in retinoblastoma 1-inducible coiled-coil protein 1 (RB1CC1) ... |
2-76 |
2.58e-40 |
|
ubiquitin-like (Ubl) domain found in retinoblastoma 1-inducible coiled-coil protein 1 (RB1CC1) and similar proteins; RB1CC1, also termed FAK family kinase-interacting protein of 200 kDa (FIP200), is the mammalian counterpart of the yeast Atg17 gene and functions as a component of the ULK1/Atg13/RB1CC1/Atg101 complex essential for induction of autophagy. RB1CC1 is a key signaling node to regulate cellular proliferation and differentiation. As a DNA-binding transcription factor, RB1CC1 has been implicated in the regulation of retinoblastoma 1 (RB1) expression. RB1CC1 contains a conserved ubiquitin-like (Ubl) domain with a beta-grasp Ubl fold, as well as a nuclear localization signal (KPRK), a leucine zipper motif and a coiled-coil structure.
Pssm-ID: 340580 Cd Length: 75 Bit Score: 143.48 E-value: 2.58e-40
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157824101 2 KLYVFLVNTGTTLTFDTELTVQTVADLKHAIQSKYKIAVQHQVLVVNGGECMTADRRVCTYSAGTDTNPIFLFNK 76
Cdd:cd17060 1 MLYVFLVNTGTMLTFDMSLAVQSVSDLKEAIEEKTKIPVEKQVLLVSGGESLDPDKRVSSYSAGTDTNPIFLFNK 75
|
|
| ATG11 |
pfam10377 |
Autophagy-related protein 11; The function of this family is conflicting. In the fission yeast, ... |
1456-1582 |
1.26e-26 |
|
Autophagy-related protein 11; The function of this family is conflicting. In the fission yeast, Schizosaccharomyces pombe, this protein has been shown to interact with the telomere cap complex and it is also required for dimerization and kinase activation of Atg1. However, in budding yeast, Saccharomyces cerevisiae, this protein is called ATG11 and is shown to be involved in autophagy.
Pssm-ID: 463063 Cd Length: 130 Bit Score: 106.53 E-value: 1.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1456 LERTLQlKEEENKRlnqrlmsQSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDN-----YVLFTVSPTLYFLHSESLP 1530
Cdd:pfam10377 14 LAKKLT-KENKSKR-------EKLEKLQSEAHEKITLKNFKVGDLALFLPTRRHNDlstppWAAFNVGAPHYFLKADSLL 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 157824101 1531 ALdlkpgegasgvSRRPWVLGKVMEKEYCQAK---KAQNRFKVPLGTKFYRVKAV 1582
Cdd:pfam10377 86 AL-----------KSREWFVGRITSIEERVVDlsdKDSNPFKLSKGTVWYLVTAE 129
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
864-1370 |
2.72e-15 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 81.61 E-value: 2.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 864 QELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQklleMENIMHTQ 943
Cdd:TIGR04523 162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQ----LKDNIEKK 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 944 NSEIKELK---QSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKeledtlhirhTEEFEKVITDHKVSLEKLKKENQQK 1020
Cdd:TIGR04523 238 QQEINEKTteiSNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK----------IKELEKQLNQLKSEISDLNNQKEQD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1021 IDQMLESHASAIQEKEQQLQ----ELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEEsRTQQKETLKSLLE---QET 1093
Cdd:TIGR04523 308 WNKELKSELKNQEKKLEEIQnqisQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE-KQNEIEKLKKENQsykQEI 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1094 ENLRTEINKLNQKIHDNSESYQvglselrslmtiEKDQCISELisrhEEESNILKAELDSVTALHHQAFEIEKKLKEQIV 1173
Cdd:TIGR04523 387 KNLESQINDLESKIQNQEKLNQ------------QKDEQIKKL----QQEKELLEKEIERLKETIIKNNSEIKDLTNQDS 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1174 ELQTKLNsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAmnheqDKEQLIQKLNFEKdeaiqtaldefklerelve 1253
Cdd:TIGR04523 451 VKELIIK-NLDNTRESLETQLKVLSRSINKIKQNLEQKQKELK-----SKEKELKKLNEEK------------------- 505
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1254 KELLEKVKHLENQIAKSpafesaredssslvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA----------E 1323
Cdd:TIGR04523 506 KELEEKVKDLTKKISSL--------------KEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEkeideknkeiE 571
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 157824101 1324 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSED 1370
Cdd:TIGR04523 572 ELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
827-1317 |
5.57e-15 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 80.45 E-value: 5.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 827 KEQCDLSNYLKCTAVEIRNI---IDKVKCSL--------EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLK 895
Cdd:TIGR04523 166 KQKEELENELNLLEKEKLNIqknIDKIKNKLlklelllsNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKT 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 896 EDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVL-----EDLKKlHDEKIE 970
Cdd:TIGR04523 246 TEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWnkelkSELKN-QEKKLE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 971 SLRAEFQCLEQ--NHLKE----LEDTLHIRHTE--EFEKVITDHKVSLEKLKKENQQKIDQmLESHASAIQEKEQQLQEL 1042
Cdd:TIGR04523 325 EIQNQISQNNKiiSQLNEqisqLKKELTNSESEnsEKQRELEEKQNEIEKLKKENQSYKQE-IKNLESQINDLESKIQNQ 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1043 KVKVSDLSDMRCKLEVELALKEaetDEIKILLEEsRTQQKETLKSLLEQETEnLRTEINKLNQKIhdnsESYQVGLSELr 1122
Cdd:TIGR04523 404 EKLNQQKDEQIKKLQQEKELLE---KEIERLKET-IIKNNSEIKDLTNQDSV-KELIIKNLDNTR----ESLETQLKVL- 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1123 slmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELqTKLNSELSALEKQKDEKITQQEEKYK 1202
Cdd:TIGR04523 474 -----------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDL-TKKISSLKEKIEKLESEKKEKESKIS 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1203 ALIQNLEKDKQRLAMNHEQDKEQLIQKlNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSS 1282
Cdd:TIGR04523 542 DLEDELNKDDFELKKENLEKEIDEKNK-EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELE 620
|
490 500 510
....*....|....*....|....*....|....*...
gi 157824101 1283 LVAELQEKLQEEKAKF---LEQLEEQEKRKNEEMQNVR 1317
Cdd:TIGR04523 621 KAKKENEKLSSIIKNIkskKNKLKQEVKQIKETIKEIR 658
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
870-1371 |
7.51e-15 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 80.06 E-value: 7.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 870 KIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKE 949
Cdd:TIGR04523 119 KNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLK 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 950 LKQsREMVLEDLKKLHDE---KIESLRAEFQCLEQNhLKELEDTLHIRHTE--EFEKVITDHKVSLEKLKKENQQKIDQm 1024
Cdd:TIGR04523 199 LEL-LLSNLKKKIQKNKSlesQISELKKQNNQLKDN-IEKKQQEINEKTTEisNTQTQLNQLKDEQNKIKKQLSEKQKE- 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1025 LESHASAIQEKEQQLQELKVKVSDLSdmrcklevelalKEAETDEIKILLEESRTQQKEtlKSLLEQETENLRTEINKLN 1104
Cdd:TIGR04523 276 LEQNNKKIKELEKQLNQLKSEISDLN------------NQKEQDWNKELKSELKNQEKK--LEEIQNQISQNNKIISQLN 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1105 QKIHDNSESYQVGLSElrslmTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQiVELQTKLNSELS 1184
Cdd:TIGR04523 342 EQISQLKKELTNSESE-----NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ-EKLNQQKDEQIK 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1185 ALEKQKdEKITQQEEKYKALIQNLEKDKQRLAmNHEQDKEQLIQKLNFEKDEaIQTALDEFKLERELVEKELLEKVKHLE 1264
Cdd:TIGR04523 416 KLQQEK-ELLEKEIERLKETIIKNNSEIKDLT-NQDSVKELIIKNLDNTRES-LETQLKVLSRSINKIKQNLEQKQKELK 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1265 NQIAKSPAFESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIIN 1344
Cdd:TIGR04523 493 SKEKELKKLNEEKKELEEKVKDLTKKISSLKEK-IEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIE 571
|
490 500
....*....|....*....|....*..
gi 157824101 1345 DLSDKLKSTMQQQERDKDLIESLSEDR 1371
Cdd:TIGR04523 572 ELKQTQKSLKKKQEEKQELIDQKEKEK 598
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
943-1311 |
2.15e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.95 E-value: 2.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 943 QNSEIKELKQSREMVLEDLKKLHDEkIESLRAEFQCLEQNhLKELEDTLhirhtEEFEKVITDHKVSLEKLKKEnQQKID 1022
Cdd:TIGR02168 675 RRREIEELEEKIEELEEKIAELEKA-LAELRKELEELEEE-LEQLRKEL-----EELSRQISALRKDLARLEAE-VEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1023 QMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEtlkslleqetenLRTEINK 1102
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE------------LRAELTL 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1103 LNQKIHDNSESYQVGLSELRSLmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSE 1182
Cdd:TIGR02168 815 LNEEAANLRERLESLERRIAAT---------ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1183 LSALEKQKDEKITQQEEkykalIQNLEKDKQRLamnheqdkEQLIQKLNfEKDEAIQTALDEFKLERELVEKELLEKVK- 1261
Cdd:TIGR02168 886 EEALALLRSELEELSEE-----LRELESKRSEL--------RRELEELR-EKLAQLELRLEGLEVRIDNLQERLSEEYSl 951
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 157824101 1262 HLENQIAKSPAFESAREDSSSLVAELQEKLQE-----EKAkfLEQLEEQEKRKNE 1311
Cdd:TIGR02168 952 TLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnLAA--IEEYEELKERYDF 1004
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1025-1308 |
2.33e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.36 E-value: 2.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1025 LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQETENLRTEINK 1102
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEyeLLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1103 LNQKIHDNSESYQVGLSELRSLmtIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSE 1182
Cdd:COG1196 307 LEERRRELEERLEELEEELAEL--EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1183 LSALEKQKdekitQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLnfEKDEAIQTALDEFKLERELVEKELLEKVKH 1262
Cdd:COG1196 385 AEELLEAL-----RAAAELAAQLEELEEAEEALLERLERLEEELEELE--EALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 157824101 1263 LENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKR 1308
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1055-1369 |
3.31e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.09 E-value: 3.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1055 KLEVELALKEAETDEIKILLEESRTQQKEtlkslLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekdqciS 1134
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEE-----LEEELEQLRKELEELSRQISALRKDLARLEAEVEQL---------E 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1135 ELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKdEKITQQEEKYKALIQNLEKDKQR 1214
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRER 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1215 LAmNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEK-----ELLEKVKHLENQIAKS-PAFESAREDSSSLVAELQ 1288
Cdd:TIGR02168 826 LE-SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELeelieELESELEALLNERASLeEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1289 EKlqEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLS 1368
Cdd:TIGR02168 905 EL--ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
.
gi 157824101 1369 E 1369
Cdd:TIGR02168 983 E 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
958-1318 |
4.96e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 74.32 E-value: 4.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 958 LEDLKKLHDEKIESLRAEFQCLEQnhLKELEDTLhirhtEEFEK-VITDHKVSLEKLKKENQQKIDQM---LESHASAIQ 1033
Cdd:TIGR02168 191 LEDILNELERQLKSLERQAEKAER--YKELKAEL-----RELELaLLVLRLEELREELEELQEELKEAeeeLEELTAELQ 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1034 EKEQQLQELKVKVSdlsdmrcKLEVELALKEAETDEIKILLEEsrtqqketlkslLEQETENLRTEINKLNQKIhdnsES 1113
Cdd:TIGR02168 264 ELEEKLEELRLEVS-------ELEEEIEELQKELYALANEISR------------LEQQKQILRERLANLERQL----EE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1114 YQVGLSELRSlmtieKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKqkdek 1193
Cdd:TIGR02168 321 LEAQLEELES-----KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ----- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1194 ITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQlIQKLNFEKDEAiqtALDEFKLERELVEKELLEKVKHLENQIAKSPAF 1273
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLERLEDRRERLQQE-IEELLKKLEEA---ELKELQAELEELEEELEELQEELERLEEALEEL 466
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 157824101 1274 ESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRT 1318
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKA 510
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
930-1367 |
9.07e-13 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.13 E-value: 9.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 930 DQKLLEMENIMHTQNSEIKELKQsREMVLEDLKKLHDEKIESLRAEFQCLEqnhlKELEDTLHIRHTEEFEkvitdhKVS 1009
Cdd:TIGR04523 60 DKNLNKDEEKINNSNNKIKILEQ-QIKDLNDKLKKNKDKINKLNSDLSKIN----SEIKNDKEQKNKLEVE------LNK 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1010 LEKLKKENQQKIDQMLEShasaIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQ--QKETLKS 1087
Cdd:TIGR04523 129 LEKQKKENKKNIDKFLTE----IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKllKLELLLS 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1088 LLE---QETENLRTEINKLNQK---IHDNSESYQVGLSELRSLMTIEKDQcISELISRHEEESNILKAELDSVTalhhqa 1161
Cdd:TIGR04523 205 NLKkkiQKNKSLESQISELKKQnnqLKDNIEKKQQEINEKTTEISNTQTQ-LNQLKDEQNKIKKQLSEKQKELE------ 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1162 fEIEKKLKEQIVELQtKLNSELSALEKQKDEKITQqeeKYKALIQNLEKDKQRLAM---NHEQDKEQLIQKLNFEKDEAI 1238
Cdd:TIGR04523 278 -QNNKKIKELEKQLN-QLKSEISDLNNQKEQDWNK---ELKSELKNQEKKLEEIQNqisQNNKIISQLNEQISQLKKELT 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1239 QTALDEFKLERELVEKE-LLEKVKHlENQiAKSPAFESAREDSSSLVAEL--QEKLQEEKAKFLEQLEEQEKRKNEEMQN 1315
Cdd:TIGR04523 353 NSESENSEKQRELEEKQnEIEKLKK-ENQ-SYKQEIKNLESQINDLESKIqnQEKLNQQKDEQIKKLQQEKELLEKEIER 430
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 157824101 1316 VRTSLIAEQQTNFNtvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESL 1367
Cdd:TIGR04523 431 LKETIIKNNSEIKD--LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI 480
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
855-1372 |
1.08e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.43 E-value: 1.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 855 EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLL 934
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 935 EMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNHLKELEDTLHIRHT-EEFEKVITDHKVSLEKL 1013
Cdd:COG1196 320 ELEEELAELEEELEELEEELEELEEELEEA-EEELEEAEAELAEAEEALLEAEAELAEAEEElEELAEELLEALRAAAEL 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1014 KKENQQKIDQM------LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKS 1087
Cdd:COG1196 399 AAQLEELEEAEeallerLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1088 L--LEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSvtALHHQAFEIE 1165
Cdd:COG1196 479 LaeLLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAA--ALQNIVVEDD 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1166 KKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEF 1245
Cdd:COG1196 557 EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1246 KLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQ 1325
Cdd:COG1196 637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 157824101 1326 TNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRA 1372
Cdd:COG1196 717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE 763
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1033-1358 |
1.25e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.05 E-value: 1.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1033 QEKEQQLQELKVKVSdLSDMRcKLEVELALKEAETDEIKILLEESRTQQKEtlkslLEQETENLRTEINKLNQKIHDNSE 1112
Cdd:COG1196 216 RELKEELKELEAELL-LLKLR-ELEAELEELEAELEELEAELEELEAELAE-----LEAELEELRLELEELELELEEAQA 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1113 SYQVGLSELRSLmtiEKDqciselISRHEEESNILKAELDsvtalhhqafeiekKLKEQIVELQTKLnSELSALEKQKDE 1192
Cdd:COG1196 289 EEYELLAELARL---EQD------IARLEERRRELEERLE--------------ELEEELAELEEEL-EELEEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1193 KITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDE-AIQTALDEFKLERELVEKELLEKVKHLENQiaksp 1271
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlEALRAAAELAAQLEELEEAEEALLERLERL----- 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1272 afESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLK 1351
Cdd:COG1196 420 --EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
....*..
gi 157824101 1352 STMQQQE 1358
Cdd:COG1196 498 EAEADYE 504
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
948-1311 |
1.38e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.18 E-value: 1.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 948 KELKQSREMVLEDLKKLHDEKiESLRAEFQCLEqNHLKELEDTLhirhtEEFEKVITDHKVSLEKLKKEnQQKIDQMLES 1027
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKREL-SSLQSELRRIE-NRLDELSQEL-----SDASRKIGEIEKEIEQLEQE-EEKLKERLEE 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1028 HASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQKI 1107
Cdd:TIGR02169 742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1108 ---HDNSESYQVGLSELRSLMTIEKDQCISelISRHEEESNILKAELDSVTAlhhqafEIEKKLKEQIVELQtKLNSELS 1184
Cdd:TIGR02169 822 nrlTLEKEYLEKEIQELQEQRIDLKEQIKS--IEKEIENLNGKKEELEEELE------ELEAALRDLESRLG-DLKKERD 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1185 ALEKQKDE---KITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKEL--LEK 1259
Cdd:TIGR02169 893 ELEAQLRElerKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIraLEP 972
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 157824101 1260 VKHLENQiakspAFESAREDSSSLVaELQEKLQEEKAKFLEQLEEQEKRKNE 1311
Cdd:TIGR02169 973 VNMLAIQ-----EYEEVLKRLDELK-EKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
842-1388 |
2.04e-12 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 72.40 E-value: 2.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 842 EIRNIIDKVKCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDA 921
Cdd:PRK03918 177 RIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRK 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 922 IvcmqhekDQKLLEMENIMHTQNSEIKELKQSREMvLEDLKKLHDE--KIESLRAEFQCLEQNHLKELED-TLHIRHTEE 998
Cdd:PRK03918 257 L-------EEKIRELEERIEELKKEIEELEEKVKE-LKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRlEEEINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 999 FEKVITDHKVSLEKLKKENQQkidqmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLevelalKEAETDEIKILLEESR 1078
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKE-----LEKRLEELEERHELYEEAKAKKEELERLKKRL------TGLTPEKLEKELEELE 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1079 TQQKEtlkslLEQETENLRTEINKLNQKIHDNSESyqvgLSELRSlMTIEKDQCISELISRHEEE-SNILKAELDSVTAL 1157
Cdd:PRK03918 398 KAKEE-----IEEEISKITARIGELKKEIKELKKA----IEELKK-AKGKCPVCGRELTEEHRKElLEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1158 HHQAFEIEKKLKEQIVELQTKLN--SELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQ----DKEQLIQKLN 1231
Cdd:PRK03918 468 LKEIEEKERKLRKELRELEKVLKkeSELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKliklKGEIKSLKKE 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1232 FEKDEAIQTALDEFKLERELVEKELLEKVKHLENQiakspAFESAREDSSSLvAELQ------------EKLQEEKAKFL 1299
Cdd:PRK03918 548 LEKLEELKKKLAELEKKLDELEEELAELLKELEEL-----GFESVEELEERL-KELEpfyneylelkdaEKELEREEKEL 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1300 EQLEEQEKRKNEEMQNVRTSL------IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:PRK03918 622 KKLEEELDKAFEELAETEKRLeelrkeLEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
|
570
....*....|....*
gi 157824101 1374 LLEEKKKLEEEVSKL 1388
Cdd:PRK03918 702 ELEEREKAKKELEKL 716
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
858-1355 |
2.47e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 72.07 E-value: 2.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 858 LKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKdsefaiiKHEKDAIVCMQhekdqkllemE 937
Cdd:pfam15921 100 LHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNT-------VHELEAAKCLK----------E 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 938 NIMHTQNSEIKELkqsREMVLEDLKKLHDekIESLRAEFQCLEQNHLKELED--TLHIRHT-EEFEKVIT--DHKVS--- 1009
Cdd:pfam15921 163 DMLEDSNTQIEQL---RKMMLSHEGVLQE--IRSILVDFEEASGKKIYEHDSmsTMHFRSLgSAISKILRelDTEISylk 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1010 ---------LEKLKKENQQKIDQMLESHASAIqekEQQLQELKVKVSDLSDmrcKLEVELALKEAETDEIKILLEESRTQ 1080
Cdd:pfam15921 238 grifpvedqLEALKSESQNKIELLLQQHQDRI---EQLISEHEVEITGLTE---KASSARSQANSIQSQLEIIQEQARNQ 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1081 QKETLKSL--LEQETENLRTEINKLNQKIHDNSESYQVGL----SELRSLMTiEKDQciselisrHEEESNILKAELDSV 1154
Cdd:pfam15921 312 NSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLvlanSELTEART-ERDQ--------FSQESGNLDDQLQKL 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1155 TA-LHHQAFE--IEKKLKEQIVELQTKLNSELSALEKQKDEKiTQQEEKYKALIQNLEKDKQrlamNHEQDKEQLIQKLN 1231
Cdd:pfam15921 383 LAdLHKREKElsLEKEQNKRLWDRDTGNSITIDHLRRELDDR-NMEVQRLEALLKAMKSECQ----GQMERQMAAIQGKN 457
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1232 --FEKDEAIQTALDEfklerelvEKELLEKVkhLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLE--------- 1300
Cdd:pfam15921 458 esLEKVSSLTAQLES--------TKEMLRKV--VEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEitklrsrvd 527
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 1301 -QLEEQEKRKNEE--MQNVRTSLIAeqqtnfntvLTREKMRKENIINDLSDKLKSTMQ 1355
Cdd:pfam15921 528 lKLQELQHLKNEGdhLRNVQTECEA---------LKLQMAEKDKVIEILRQQIENMTQ 576
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
855-1318 |
6.59e-12 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 70.52 E-value: 6.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 855 EITLKEKH-QQELQSLKIEYECKLNT---LEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVC------ 924
Cdd:pfam05483 286 ELIEKKDHlTKELEDIKMSLQRSMSTqkaLEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCsleell 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 925 ------MQHEKDQ-KLLEMEniMHTQNSEIKE---LKQSREMVLEDLKKLHDEK---------IESLRAEFQCLEQN--- 982
Cdd:pfam05483 366 rteqqrLEKNEDQlKIITME--LQKKSSELEEmtkFKNNKEVELEELKKILAEDeklldekkqFEKIAEELKGKEQElif 443
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 983 ---------HLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQQ---KIDQMLESHASAIQEKEQQLQELKVKVSDLS 1050
Cdd:pfam05483 444 llqarekeiHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltaHCDKLLLENKELTQEASDMTLELKKHQEDII 523
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1051 DmrCKLEVELALKEAETdeikilLEESRTQQKETLKSLLEqETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKD 1130
Cdd:pfam05483 524 N--CKKQEERMLKQIEN------LEEKEMNLRDELESVRE-EFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILEN 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1131 QCiselisrheeesNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEkITQQEEKYKALIQNLEK 1210
Cdd:pfam05483 595 KC------------NNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELE-LASAKQKFEEIIDNYQK 661
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1211 DKQRLAMNHEQDKEQlIQKLNFEKDEAIQTALD-EFKLERELVEK-ELLEKVKH-----LENQIAKSPAFESAREDSSSL 1283
Cdd:pfam05483 662 EIEDKKISEEKLLEE-VEKAKAIADEAVKLQKEiDKRCQHKIAEMvALMEKHKHqydkiIEERDSELGLYKNKEQEQSSA 740
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 157824101 1284 VAELQEKLQEEKAKFLE-------QLEEQEKRKNEEMQNVRT 1318
Cdd:pfam05483 741 KAALEIELSNIKAELLSlkkqleiEKEEKEKLKMEAKENTAI 782
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
935-1363 |
9.91e-12 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 70.46 E-value: 9.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 935 EMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKiESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKLK 1014
Cdd:TIGR00606 574 QLEDWLHSKSKEINQTRDRLAKLNKELASLEQNK-NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSS 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1015 KEN----------QQKIDQMLESHASA------IQEKEQQLQE----LKVKVSDLSDMRCKLEVELALKEAETDEIKILL 1074
Cdd:TIGR00606 653 KQRamlagatavySQFITQLTDENQSCcpvcqrVFQTEAELQEfisdLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLA 732
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1075 EesrtqQKETLKSLLEQETENLRTEINKLNQKIhdnsesyqvglSELRSlmTIEKDQCISELISRHEEESNILKAELDSV 1154
Cdd:TIGR00606 733 P-----GRQSIIDLKEKEIPELRNKLQKVNRDI-----------QRLKN--DIEEQETLLGTIMPEEESAKVCLTDVTIM 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1155 TALHHQAFEIEKKLKEQIVELQTklnSELSALEKQKDEKITQQEEKYKALIQNLEKDkQRLAMNHEQDKEQLIQKLNFEK 1234
Cdd:TIGR00606 795 ERFQMELKDVERKIAQQAAKLQG---SDLDRTVQQVNQEKQEKQHELDTVVSKIELN-RKLIQDQQEQIQHLKSKTNELK 870
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1235 DEAIQtaLDEFKLERELVEKELLEKVKHLENQIAkspAFESAREDSSSLvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1314
Cdd:TIGR00606 871 SEKLQ--IGTNLQRRQQFEEQLVELSTEVQSLIR---EIKDAKEQDSPL-ETFLEKDQQEKEELISSKETSNKKAQDKVN 944
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 157824101 1315 NVRTSL---IAEQQTNFNTV---LTREKMRKENIINDLSDKLKSTMQQQER-DKDL 1363
Cdd:TIGR00606 945 DIKEKVkniHGYMKDIENKIqdgKDDYLKQKETELNTVNAQLEECEKHQEKiNEDM 1000
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1142-1373 |
3.55e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 68.42 E-value: 3.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1142 EESNILKAELdsvTALHHQAFEIE-KKLKEQIVELQTKLNSELSALEkQKDEKITQQEEKYKALIQNLEKDKQRLAmNHE 1220
Cdd:COG1196 220 EELKELEAEL---LLLKLRELEAElEELEAELEELEAELEELEAELA-ELEAELEELRLELEELELELEEAQAEEY-ELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1221 QDKEQLIQKLNFEKD--EAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKF 1298
Cdd:COG1196 295 AELARLEQDIARLEErrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157824101 1299 LEQLEEQEKRKNEEMQNVRTSL-IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
859-1372 |
3.80e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.16 E-value: 3.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 859 KEKHQQELQSLKIEYEcklnTLEKDSEENVNKILKLKEDLVSLEEalqnkdsEFAIIKHEKDAIVCMQHEKDQKLLEMEN 938
Cdd:TIGR02168 304 KQILRERLANLERQLE----ELEAQLEELESKLDELAEELAELEE-------KLEELKEELESLEAELEELEAELEELES 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 939 IMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNH------LKELEDTLHIRHTEEFEKVITDHKVSLEK 1012
Cdd:TIGR02168 373 RLEELEEQLETLRSKVAQLELQIASL-NNEIERLEARLERLEDRRerlqqeIEELLKKLEEAELKELQAELEELEEELEE 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1013 LKKENQQKIDQmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESR--TQQKETLKSLLE 1090
Cdd:TIGR02168 452 LQEELERLEEA-LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglSGILGVLSELIS 530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1091 QEtENLRTEINK-----LNQKIHDNSESYQVGLSELRS----------LMTIEKDQCISELISRHEEESNILKAELDSVT 1155
Cdd:TIGR02168 531 VD-EGYEAAIEAalggrLQAVVVENLNAAKKAIAFLKQnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1156 A-----------LHH--------QAFEIEKKLKEQ--IVELQTKL------------NSELSALEKQKD-EKITQQEEKY 1201
Cdd:TIGR02168 610 FdpklrkalsylLGGvlvvddldNALELAKKLRPGyrIVTLDGDLvrpggvitggsaKTNSSILERRREiEELEEKIEEL 689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1202 KALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKE-LLEKVKHLENQIAKSPAFESAREDS 1280
Cdd:TIGR02168 690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEELEER 769
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1281 sslVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSLIAEQQ--TNFNTVLTREKMRKENIINDLSDKLKS---TMQ 1355
Cdd:TIGR02168 770 ---LEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAelTLLNEEAANLRERLESLERRIAATERRledLEE 845
|
570
....*....|....*..
gi 157824101 1356 QQERDKDLIESLSEDRA 1372
Cdd:TIGR02168 846 QIEELSEDIESLAAEIE 862
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
829-1255 |
3.84e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.09 E-value: 3.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 829 QCDLSNYLKCTAVEIRNIIDKVKcsleitlkekhqqelqslkieyecklNTLEKDSeenvnKILKLKEDlvsLEEALQNK 908
Cdd:TIGR02169 141 QGDVTDFISMSPVERRKIIDEIA--------------------------GVAEFDR-----KKEKALEE---LEEVEENI 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 909 DSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQnHLKELE 988
Cdd:TIGR02169 187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI-ERQLASLEEELEKLTE-EISELE 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 989 DTLhirhtEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETD 1068
Cdd:TIGR02169 265 KRL-----EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1069 EIKillEESRTQQKEtlKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekDQCISELISRHEEesniLK 1148
Cdd:TIGR02169 340 ELE---REIEEERKR--RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY-----REKLEKLKREINE----LK 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1149 AELDSVTALHHQAFEIEKKLKEQIVELQTKLNsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLamnheQDKEQLIQ 1228
Cdd:TIGR02169 406 RELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL-----YDLKEEYD 479
|
410 420
....*....|....*....|....*..
gi 157824101 1229 KLNFEKDEaiqtaldefkLERELVEKE 1255
Cdd:TIGR02169 480 RVEKELSK----------LQRELAEAE 496
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1064-1392 |
5.09e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 5.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1064 EAETDEIKILLEES------RTQQKETLKSLLEQET-----ENLRTEINKLNQKIHDNSESYQvglsELRSLMTIEKDQC 1132
Cdd:TIGR02168 151 EAKPEERRAIFEEAagiskyKERRKETERKLERTREnldrlEDILNELERQLKSLERQAEKAE----RYKELKAELRELE 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1133 ISELISRHEEesniLKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNsELSALEKQKDEKITQQEEKYKAL---IQNLE 1209
Cdd:TIGR02168 227 LALLVLRLEE----LREELEELQEELKEAEEELEELTAELQELEEKLE-ELRLEVSELEEEIEELQKELYALaneISRLE 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1210 KDKQRLAMNHEQDKEQlIQKLNFEKDEAIQTaLDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQE 1289
Cdd:TIGR02168 302 QQKQILRERLANLERQ-LEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1290 KLQEEKAKFLeQLEEQEKRKNEEMQNVRTSL--IAEQQTNFNTVLT-----REKMRKENIINDLSDKLKSTMQQQERDKD 1362
Cdd:TIGR02168 380 QLETLRSKVA-QLELQIASLNNEIERLEARLerLEDRRERLQQEIEellkkLEEAELKELQAELEELEEELEELQEELER 458
|
330 340 350
....*....|....*....|....*....|
gi 157824101 1363 LIESLSEDRARLLEEKKKLEEEVSKLRTSS 1392
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQ 488
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
855-1373 |
1.18e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 1.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 855 EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKD---- 930
Cdd:TIGR02168 247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEaqle 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 931 ---QKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLH-------------DEKIESLRAEFQCLEQ------NHLKELE 988
Cdd:TIGR02168 327 eleSKLDELAEELAELEEKLEELKEELESLEAELEELEaeleelesrleelEEQLETLRSKVAQLELqiaslnNEIERLE 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 989 DTLHI--RHTEEFEKVITDHKVSLEKLKKENQQ----KIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELAL 1062
Cdd:TIGR02168 407 ARLERleDRRERLQQEIEELLKKLEEAELKELQaeleELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1063 KEAETDEIKILLEESRTQQKETLKSLLEQE---------------TENLRTEINK-----LNQKIHDNSESYQVGLSELR 1122
Cdd:TIGR02168 487 LQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvDEGYEAAIEAalggrLQAVVVENLNAAKKAIAFLK 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1123 S----------LMTIEKDQCISELISRHEEESNILKAELDSVTA-----------LHH--------QAFEIEKKLKEQ-- 1171
Cdd:TIGR02168 567 QnelgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFdpklrkalsylLGGvlvvddldNALELAKKLRPGyr 646
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1172 IVELQTKL------------NSELSALEKQKD-EKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAI 1238
Cdd:TIGR02168 647 IVTLDGDLvrpggvitggsaKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1239 QTALDEFKLERELVEKELLEKV-----KHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKF------LEQLEEQEK 1307
Cdd:TIGR02168 727 QISALRKDLARLEAEVEQLEERiaqlsKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlkeeLKALREALD 806
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157824101 1308 RKNEEMQNVRTSliAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:TIGR02168 807 ELRAELTLLNEE--AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE 870
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1114-1373 |
1.90e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 62.65 E-value: 1.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1114 YQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALE--KQKD 1191
Cdd:COG1196 218 LKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYelLAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1192 EKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQ-----KLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQ 1266
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEEleeelEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1267 IAKSPAFESAREDSSSLVAELQEKLQ------EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQT--NFNTVLTREKMR 1338
Cdd:COG1196 378 EEELEELAEELLEALRAAAELAAQLEeleeaeEALLERLERLEEELEELEEALAELEEEEEEEEEAleEAAEEEAELEEE 457
|
250 260 270
....*....|....*....|....*....|....*
gi 157824101 1339 KENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
861-1320 |
2.46e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.50 E-value: 2.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 861 KHQQELQSL--KIEYEC-KLNTLEKDSEENVNKILKLKEDLVSlEEALQNKDSefaiiKHEKDaivcMQHEKDQKLLEME 937
Cdd:pfam01576 240 KKEEELQAAlaRLEEETaQKNNALKKIRELEAQISELQEDLES-ERAARNKAE-----KQRRD----LGEELEALKTELE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 938 NIMHTQNSEiKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELED-TLHIRHTEEFEKVITDHKVSLEKLKKE 1016
Cdd:pfam01576 310 DTLDTTAAQ-QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEElTEQLEQAKRNKANLEKAKQALESENAE 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1017 NQQKIDQMLESHASAIQEK---EQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESrtqqketlksllEQET 1093
Cdd:pfam01576 389 LQAELRTLQQAKQDSEHKRkklEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEA------------EGKN 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1094 ENLRTEINKLNQKIHDNSESYQ----VGLSELRSLMTIEKDQciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLK 1169
Cdd:pfam01576 457 IKLSKDVSSLESQLQDTQELLQeetrQKLNLSTRLRQLEDER--NSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1170 ------EQIVELQTKLNSELSALEKQKDEKITQQE--EKYKALIQN------LEKDKQR-LAMNHEQDKEQLIQKLNFEK 1234
Cdd:pfam01576 535 edagtlEALEEGKKRLQRELEALTQQLEEKAAAYDklEKTKNRLQQelddllVDLDHQRqLVSNLEKKQKKFDQMLAEEK 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1235 DEAIQTALDEFKLERELVEKE--LLEKVKHLENQIAKSPAFESAREdssSLVAELQEKL--QEEKAKFLEQLEEQEKRKN 1310
Cdd:pfam01576 615 AISARYAEERDRAEAEAREKEtrALSLARALEEALEAKEELERTNK---QLRAEMEDLVssKDDVGKNVHELERSKRALE 691
|
490
....*....|
gi 157824101 1311 EEMQNVRTSL 1320
Cdd:pfam01576 692 QQVEEMKTQL 701
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
851-1107 |
3.68e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.61 E-value: 3.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 851 KCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKD 930
Cdd:TIGR02168 744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 931 QKLLEMENIMHTQNSEIKELKQSREMVLEDlkklhdekIESLRAEfqcleQNHLKELEDTLHIRHtEEFEKVITDHKVSL 1010
Cdd:TIGR02168 824 ERLESLERRIAATERRLEDLEEQIEELSED--------IESLAAE-----IEELEELIEELESEL-EALLNERASLEEAL 889
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1011 EKLKKENQQKIDQmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELA-LKEAETDEIKILLEESrtqqkETLKSLL 1089
Cdd:TIGR02168 890 ALLRSELEELSEE-LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnLQERLSEEYSLTLEEA-----EALENKI 963
|
250
....*....|....*...
gi 157824101 1090 EQETENLRTEINKLNQKI 1107
Cdd:TIGR02168 964 EDDEEEARRRLKRLENKI 981
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
856-1308 |
4.06e-09 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 61.78 E-value: 4.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 856 ITLKEKHQQELQSLKIEYECKLNTLEKDSEEnvnKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLE 935
Cdd:pfam12128 271 ETLIASRQEERQETSAELNQLLRTLDDQWKE---KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 936 MENIMHTQNSEikelkqsremvLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHT------EEFEKVITDHKVS 1009
Cdd:pfam12128 348 QLPSWQSELEN-----------LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDklakirEARDRQLAVAEDD 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1010 LEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDL---SDMRCKLEV-ELALKEAETDEIKILLEESRTQQKET- 1084
Cdd:pfam12128 417 LQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQAtatPELLLQLENfDERIERAREEQEAANAEVERLQSELRq 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1085 LKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMT-IEKD-----QCISELISRHEEESNILKAELDSVTA-- 1156
Cdd:pfam12128 497 ARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHfLRKEapdweQSIGKVISPELLHRTDLDPEVWDGSVgg 576
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1157 --------LHHQAFEI------EKKLKEQIVELQTKLNSELS---ALEKQ------KDEKITQQEEKYKALIQNLEKDKQ 1213
Cdd:pfam12128 577 elnlygvkLDLKRIDVpewaasEEELRERLDKAEEALQSAREkqaAAEEQlvqangELEKASREETFARTALKNARLDLR 656
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1214 RLAMNHEQDKEQLIQKLNFEKDEAIQ--TALDEFKLERELVEKELLEKVKH--LENQIAKSPAF---ESAREDSSSLVAE 1286
Cdd:pfam12128 657 RLFDEKQSEKDKKNKALAERKDSANErlNSLEAQLKQLDKKHQAWLEEQKEqkREARTEKQAYWqvvEGALDAQLALLKA 736
|
490 500
....*....|....*....|..
gi 157824101 1287 LQEKLQEEKAKFLEQLEEQEKR 1308
Cdd:pfam12128 737 AIAARRSGAKAELKALETWYKR 758
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1027-1291 |
4.19e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 60.55 E-value: 4.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1027 SHASAIQEKEQQLQELKVKVSDLSDmrcklevELALKEAETDEIKILLEESRTQQKETLKSL--LEQETENLRTEINKLN 1104
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEK-------ELAALKKEEKALLKQLAALERRIAALARRIraLEQELAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1105 QKIHDNSESYQVGLSELRSLMTiekdqcISELISRHEEESNILKAElDSVTALHhqAFEIEKKLKEQIVELQTKLNSELS 1184
Cdd:COG4942 90 KEIAELRAELEAQKEELAELLR------ALYRLGRQPPLALLLSPE-DFLDAVR--RLQYLKYLAPARREQAEELRADLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1185 ALEKQKDEKITQQEEKyKALIQNLEKDKQRLAMNhEQDKEQLIQKLNFEKdEAIQTALDEFKLErelvEKELLEKVKHLE 1264
Cdd:COG4942 161 ELAALRAELEAERAEL-EALLAELEEERAALEAL-KAERQKLLARLEKEL-AELAAELAELQQE----AEELEALIARLE 233
|
250 260
....*....|....*....|....*..
gi 157824101 1265 NQIAkspafESAREDSSSLVAELQEKL 1291
Cdd:COG4942 234 AEAA-----AAAERTPAAGFAALKGKL 255
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
892-1243 |
4.27e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.62 E-value: 4.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 892 LKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLH------ 965
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEedlssl 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 966 DEKIESLRAEFQCLEQ---------NHLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQ---QKIDQMLESHASAIQ 1033
Cdd:TIGR02169 750 EQEIENVKSELKELEArieeleedlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1034 EKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQETENLRTEINKLNQKIHDNS 1111
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLgdLKKERDELEAQLRELERKIEELE 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1112 ESYQ---VGLSELRSLMTIEKDQcISELISRHEEESNILKAELDsvtalhhqafeiEKKLKEQIVELQtklnSELSALEK 1188
Cdd:TIGR02169 910 AQIEkkrKRLSELKAKLEALEEE-LSEIEDPKGEDEEIPEEELS------------LEDVQAELQRVE----EEIRALEP 972
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 157824101 1189 QKDEKITQQEEKYKALiQNLEKDKQRLAMNHEQDKEqLIQKLNFEKDEAIQTALD 1243
Cdd:TIGR02169 973 VNMLAIQEYEEVLKRL-DELKEKRAKLEEERKAILE-RIEEYEKKKREVFMEAFE 1025
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1012-1369 |
1.02e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.08 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1012 KLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAET---DEIKILLEESRTQQKETLKSL 1088
Cdd:PRK03918 175 KRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVkelEELKEEIEELEKELESLEGSK 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1089 ---------LEQETENLRTEINKLNQKIHDNSE--SYQVGLSELRSLM--TIEKDQCISELISRHEEESNILKAELDSVT 1155
Cdd:PRK03918 255 rkleekireLEERIEELKKEIEELEEKVKELKElkEKAEEYIKLSEFYeeYLDELREIEKRLSRLEEEINGIEERIKELE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1156 ALHHQAFEIEKKLKEqivelqtkLNSELSALEKQkdekiTQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKD 1235
Cdd:PRK03918 335 EKEERLEELKKKLKE--------LEKRLEELEER-----HELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1236 EaIQTALDEFKLER---ELVEKELLEKVKHLENQIAKSPAF--ESAREDSSSLVAELQEKLqEEKAKFLEQLEEQEKRKN 1310
Cdd:PRK03918 402 E-IEEEISKITARIgelKKEIKELKKAIEELKKAKGKCPVCgrELTEEHRKELLEEYTAEL-KRIEKELKEIEEKERKLR 479
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1311 EEMQNVRTSLIAEQQtnfntvLTREKMRKENIINdLSDKLKS-TMQQQERDKDLIESLSE 1369
Cdd:PRK03918 480 KELRELEKVLKKESE------LIKLKELAEQLKE-LEEKLKKyNLEELEKKAEEYEKLKE 532
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
847-1538 |
1.25e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.99 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 847 IDKVKCSLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKI----LKLKEDLVSLEEALQNKDSEFAIIKHEKD-- 920
Cdd:pfam02463 164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKaleyYQLKEKLELEEEYLLYLDYLKLNEERIDLlq 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 921 ---AIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNH-LKELEDTLHIRHT 996
Cdd:pfam02463 244 ellRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKvDDEEKLKESEKEK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 997 EEFEKVITDHKVS---LEKLKKE-------NQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAE 1066
Cdd:pfam02463 324 KKAEKELKKEKEEieeLEKELKEleikreaEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1067 TDEIKILLEESRTQ----QKETLKSLLEQETENLRTEINKLNQKIHDNSESYQV------GLSELRSLMTIEKDQCISEL 1136
Cdd:pfam02463 404 EKEAQLLLELARQLedllKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQElkllkdELELKKSEDLLKETQLVKLQ 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1137 ISR------------------HEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQT--KLNSELSALEKQKDEKITQ 1196
Cdd:pfam02463 484 EQLelllsrqkleersqkeskARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKvaISTAVIVEVSATADEVEER 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1197 QEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLN--------------FEKDEAIQTALDEFKLERELVEKELLEKVKH 1262
Cdd:pfam02463 564 QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlaqldkatLEADEDDKRAKVVEGILKDTELTKLKESAKA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1263 LENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQ-------------------------LEEQEKRKNEEMQNVR 1317
Cdd:pfam02463 644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQekaeselakeeilrrqleikkkeqrEKEELKKLKLEAEELL 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1318 TSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRTSSVLPSA 1397
Cdd:pfam02463 724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1398 PVLAAPELYGACAPELPGEPERSAMETTDEGRVDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEEN-KRLNQRLMS 1476
Cdd:pfam02463 804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLlKEEELEEQK 883
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157824101 1477 QSLSSVSSRHSEKIAIRDFQVGDLVLIILDERHDNYVLFTVSPTLYFLHSESLPALDLKPGE 1538
Cdd:pfam02463 884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
948-1245 |
1.43e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 1.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 948 KELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHlKELEDTLHIRHTEefekvITDHKVSLEKLKKEnQQKIDQMLES 1027
Cdd:TIGR02168 220 AELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEK-----LEELRLEVSELEEE-IEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1028 HASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQETENLRTEINKLNQ 1105
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELesLEAELEELEAELEELES 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1106 KIHDnsesYQVGLSELRSlmtiekdqciseLISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNS---- 1181
Cdd:TIGR02168 373 RLEE----LEEQLETLRS------------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEaelk 436
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 1182 ELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHE--QDKEQLIQKLNFEKD--EAIQTALDEF 1245
Cdd:TIGR02168 437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQalDAAERELAQLQARLDslERLQENLEGF 504
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
896-1370 |
2.43e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 59.21 E-value: 2.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 896 EDLVSLEEALQNKDSEFAIiKHEKDA----IVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREM-------VLEDLKKL 964
Cdd:TIGR00618 341 EEQRRLLQTLHSQEIHIRD-AHEVATsireISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIlqreqatIDTRTSAF 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 965 HDEKIESLRAEFQC-LEQNHLKELEdtLHIRHTEEFEKVITDHKVSLEKLKKENQQKI---DQMLESHASAIQEKEQQLQ 1040
Cdd:TIGR00618 420 RDLQGQLAHAKKQQeLQQRYAELCA--AAITCTAQCEKLEKIHLQESAQSLKEREQQLqtkEQIHLQETRKKAVVLARLL 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1041 ELKVKVSDLsdmrCKLEVELALKEAETDEIKILleESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSE 1120
Cdd:TIGR00618 498 ELQEEPCPL----CGSCIHPNPARQDIDNPGPL--TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS 571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1121 LRSLmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKL----KEQIVELQTKLNS-ELSALEKQKDEKIT 1195
Cdd:TIGR00618 572 FSIL---------TQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLaceqHALLRKLQPEQDLqDVRLHLQQCSQELA 642
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1196 QQEEKYKALIQNLEKDKQR--LAMNHEQDKEQLIQKLNFEKdeAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAF 1273
Cdd:TIGR00618 643 LKLTALHALQLTLTQERVRehALSIRVLPKELLASRQLALQ--KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1274 ESAREDSSSLVAELQ-------EKLQEEKAKFLEQLEEQEkrkNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDL 1346
Cdd:TIGR00618 721 NEIENASSSLGSDLAaredalnQSLKELMHQARTVLKART---EAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREED 797
|
490 500
....*....|....*....|....*.
gi 157824101 1347 SDKLKSTMQQ--QERDKDLIESLSED 1370
Cdd:TIGR00618 798 THLLKTLEAEigQEIPSDEDILNLQC 823
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
892-1369 |
2.93e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.58 E-value: 2.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 892 LKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDekies 971
Cdd:pfam05483 215 FKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIE----- 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 972 lraefqclEQNHL-KELEDTlhirhteefeKVITDHKVSLEKLKKENQQ----KIDQMLESHASAIQEKEQQLQELKVKV 1046
Cdd:pfam05483 290 --------KKDHLtKELEDI----------KMSLQRSMSTQKALEEDLQiatkTICQLTEEKEAQMEELNKAKAAHSFVV 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1047 SDLSDMRCKLE----VELALKEAETDEIKILLEE-----SRTQQKETLKSLLEQETENLRTEINKlNQKIHDNSESYQVG 1117
Cdd:pfam05483 352 TEFEATTCSLEellrTEQQRLEKNEDQLKIITMElqkksSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKI 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1118 LSELRSlmtieKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKlNSELSA------------ 1185
Cdd:pfam05483 431 AEELKG-----KEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK-NIELTAhcdklllenkel 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1186 ----------LEKQKDEKIT--QQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQ-----KLNFEKDEAIQTALDEFKLE 1248
Cdd:pfam05483 505 tqeasdmtleLKKHQEDIINckKQEERMLKQIENLEEKEMNLRDELESVREEFIQkgdevKCKLDKSEENARSIEYEVLK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1249 RELVEKELLEKVKHLENQIA-KSPAFESAREDSSSL-----VAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA 1322
Cdd:pfam05483 585 KEKQMKILENKCNNLKKQIEnKNKNIEELHQENKALkkkgsAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIE 664
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 157824101 1323 EQQTNFNTVLtrEKMRKENIINDLSDKLkstmqQQERDKDLIESLSE 1369
Cdd:pfam05483 665 DKKISEEKLL--EEVEKAKAIADEAVKL-----QKEIDKRCQHKIAE 704
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
855-1369 |
3.07e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 58.90 E-value: 3.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 855 EITLKEKHQQELQSLKIEYECKLNTLE---KDSEENVNKILKLKEDLVSL------------------EEALQNKDSEFA 913
Cdd:TIGR00606 225 QITSKEAQLESSREIVKSYENELDPLKnrlKEIEHNLSKIMKLDNEIKALksrkkqmekdnselelkmEKVFQGTDEQLN 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 914 IIKHEKDAIVcmqHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKL------HDEKIE---------SLRAEFQC 978
Cdd:TIGR00606 305 DLYHNHQRTV---REKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLqlqadrHQEHIRardsliqslATRLELDG 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 979 LEQNHLKELE----DTLHIRHTEEFEKVITDHKVSL---EKLKKENQQKIDQMLESHASAIQEK----EQQLQELKVKVS 1047
Cdd:TIGR00606 382 FERGPFSERQiknfHTLVIERQEDEAKTAAQLCADLqskERLKQEQADEIRDEKKGLGRTIELKkeilEKKQEELKFVIK 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1048 DLSD----MRCKLEVELALKEAETDeIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQKIHD-NSESYQVGLSELR 1122
Cdd:TIGR00606 462 ELQQlegsSDRILELDQELRKAERE-LSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQlNHHTTTRTQMEML 540
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1123 SLMTIEKDQCISELISRHEEESNILKAELDSVTALhHQAFEIEKKLKEQIVELQTKLNSELSALEKQKD------EKITQ 1196
Cdd:TIGR00606 541 TKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQL-EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNhinnelESKEE 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1197 QEEKYKALI------QNLEKDKQRLAMNHEQDKEQL-------------IQKLNFEKDEAIQTALDEFKLERELVE---- 1253
Cdd:TIGR00606 620 QLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRamlagatavysqfITQLTDENQSCCPVCQRVFQTEAELQEfisd 699
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1254 -----KELLEKVKHLENQIAKspafESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSlIAEQQTNF 1328
Cdd:TIGR00606 700 lqsklRLAPDKLKSTESELKK----KEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND-IEEQETLL 774
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 157824101 1329 NTVLTREKMrKENIINDLSDKLKSTMQQQERDKDLIESLSE 1369
Cdd:TIGR00606 775 GTIMPEEES-AKVCLTDVTIMERFQMELKDVERKIAQQAAK 814
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
851-1370 |
5.52e-08 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 57.44 E-value: 5.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 851 KCSLEITLKEKHQQELQ--SLKIEYECKLNTLEKDSEENVNK-------ILKLKEDLVSLEEALQNKDSEFAIIKHEKDA 921
Cdd:pfam05557 8 KARLSQLQNEKKQMELEhkRARIELEKKASALKRQLDRESDRnqelqkrIRLLEKREAEAEEALREQAELNRLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 922 IVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMvledlkklHDEKIESLRAEFQCLEQNHlkeleDTLHIRHTeEFEK 1001
Cdd:pfam05557 88 LNKKLNEKESQLADAREVISCLKNELSELRRQIQR--------AELELQSTNSELEELQERL-----DLLKAKAS-EAEQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1002 VITDHKVSLEKLkKENQQKIdQMLESHasaIQEKEQQLQELKVKVSDLSDMRcKLEVELalkEAETDEIKILLEESRTqq 1081
Cdd:pfam05557 154 LRQNLEKQQSSL-AEAEQRI-KELEFE---IQSQEQDSEIVKNSKSELARIP-ELEKEL---ERLREHNKHLNENIEN-- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1082 ketlKSLLEQETENLRTEINKLnQKIHDNSESYQVGLS----ELRSLMTIEKDQCIS----ELISRH----EEESNILKA 1149
Cdd:pfam05557 223 ----KLLLKEEVEDLKRKLERE-EKYREEAATLELEKEkleqELQSWVKLAQDTGLNlrspEDLSRRieqlQQREIVLKE 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1150 ELDSVT----ALHHQAFEIEKKLK---EQIVELQTKLNSELSALEKQKDEKI--TQQEEKYKALIQNLEKDkqrLAM-NH 1219
Cdd:pfam05557 298 ENSSLTssarQLEKARRELEQELAqylKKIEDLNKKLKRHKALVRRLQRRVLllTKERDGYRAILESYDKE---LTMsNY 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1220 EQDK-------EQLIQKLNfEKDEAIQTALDefKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQ 1292
Cdd:pfam05557 375 SPQLlerieeaEDMTQKMQ-AHNEEMEAQLS--VAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEVDSLRRKLE 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1293 EEKAkfleQLEEQEKRKNE-EMQNVRTSLiaeqQTNFNTVLTREKMRKENIINDLSDKLKSTMQQ----QERDKDLIESL 1367
Cdd:pfam05557 452 TLEL----ERQRLREQKNElEMELERRCL----QGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKlqaeIERLKRLLKKL 523
|
...
gi 157824101 1368 SED 1370
Cdd:pfam05557 524 EDD 526
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
863-1314 |
5.81e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 57.88 E-value: 5.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 863 QQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQnkdsefaiikHEKDAIVCMQHEK---DQKLLEME-- 937
Cdd:pfam01576 70 KQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLD----------EEEAARQKLQLEKvttEAKIKKLEed 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 938 -NIMHTQNSEI-KELKQSREMVLEDLKKLHDE--KIESLraefqcleqNHLKEledtlhirhteEFEKVITDHKVSLEKL 1013
Cdd:pfam01576 140 iLLLEDQNSKLsKERKLLEERISEFTSNLAEEeeKAKSL---------SKLKN-----------KHEAMISDLEERLKKE 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1014 KKENQQ--KIDQMLESHASAIQEKeqqlqelkvkVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--- 1088
Cdd:pfam01576 200 EKGRQEleKAKRKLEGESTDLQEQ----------IAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIrel 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1089 ------LEQETENLRTEINKLNQKIHDNSESYQVGLSELRSlmTIEKDQCISELISRHEEESNILKAELDSVTALHHQaf 1162
Cdd:pfam01576 270 eaqiseLQEDLESERAARNKAEKQRRDLGEELEALKTELED--TLDTTAAQQELRSKREQEVTELKKALEEETRSHEA-- 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1163 eiekklkeQIVELQTKLNSELsalekqkdEKITQQEEKYKALIQNLEKDKQ-------------RLAMNHEQDKEQLIQK 1229
Cdd:pfam01576 346 --------QLQEMRQKHTQAL--------EELTEQLEQAKRNKANLEKAKQalesenaelqaelRTLQQAKQDSEHKRKK 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1230 LNFEKDEaIQTALDEFKLERElvekELLEKVKHLENQI---------AKSPAFESAREDSS--SLVAELQEKLQEE---- 1294
Cdd:pfam01576 410 LEGQLQE-LQARLSESERQRA----ELAEKLSKLQSELesvssllneAEGKNIKLSKDVSSleSQLQDTQELLQEEtrqk 484
|
490 500 510
....*....|....*....|....*....|....
gi 157824101 1295 -------------KAKFLEQLEEQ-EKRKNEEMQ 1314
Cdd:pfam01576 485 lnlstrlrqledeRNSLQEQLEEEeEAKRNVERQ 518
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
859-1254 |
8.14e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 57.22 E-value: 8.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 859 KEKHQQELQSLKiEYECKLNTLEKdSEENVNKilKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMEN 938
Cdd:PRK01156 348 YDDLNNQILELE-GYEMDYNSYLK-SIESLKK--KIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 939 IMHTQNSEIKELKQSREMVLEDLKKLH-------------DEKIESLRAEFQcleqNHLKELEDtlHIRHTEEFEKVITD 1005
Cdd:PRK01156 424 KVSSLNQRIRALRENLDELSRNMEMLNgqsvcpvcgttlgEEKSNHIINHYN----EKKSRLEE--KIREIEIEVKDIDE 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1006 HKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEvelALKEaETDEIKI-LLEESRTQQKET 1084
Cdd:PRK01156 498 KIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYE---EIKN-RYKSLKLeDLDSKRTSWLNA 573
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1085 LKSLLEQETENLRTEINKLNQKIHDNSEsyqvGLSELRSlmTIEKDQC-ISELISRHEEESNILKAELDSVTALHHQAFE 1163
Cdd:PRK01156 574 LAVISLIDIETNRSRSNEIKKQLNDLES----RLQEIEI--GFPDDKSyIDKSIREIENEANNLNNKYNEIQENKILIEK 647
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1164 IEKK---LKEQIVELQTKLNSelsalEKQKDEKITQQEEKYKAL---IQNLEKDKQRLAMNHE---QDKEQLIQKLN--- 1231
Cdd:PRK01156 648 LRGKidnYKKQIAEIDSIIPD-----LKEITSRINDIEDNLKKSrkaLDDAKANRARLESTIEilrTRINELSDRINdin 722
|
410 420
....*....|....*....|....*
gi 157824101 1232 --FEKDEAIQTALDEFKLERELVEK 1254
Cdd:PRK01156 723 etLESMKKIKKAIGDLKRLREAFDK 747
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
996-1325 |
1.02e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 996 TEEFEKVITDHKVSLEKLKkENQQKIDQMLEshasaiqEKEQQLQEL------KVKVSDLSDMRCKLEVELALKEaetde 1069
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVE-ENIERLDLIID-------EKRQQLERLrrerekAERYQALLKEKREYEGYELLKE----- 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1070 ikilLEESRTQQKETLKSL--LEQETENLRTEINKLNQKIHdnsesyqvglSELRSLMTIEKDqcISELisrHEEESNIL 1147
Cdd:TIGR02169 232 ----KEALERQKEAIERQLasLEEELEKLTEEISELEKRLE----------EIEQLLEELNKK--IKDL---GEEEQLRV 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1148 KAELDSVTALHHQAFEIEKKLKEQIVELQ---TKLNSELSALEKQK---DEKITQQEEKYKALIQNLEKDKQRLAmnheq 1221
Cdd:TIGR02169 293 KEKIGELEAEIASLERSIAEKERELEDAEerlAKLEAEIDKLLAEIeelEREIEEERKRRDKLTEEYAELKEELE----- 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1222 DKEQLIQklnfEKDEAIQTALDEFKLERELVEK--------------------ELLEKVKHLENQIA----KSPAFESAR 1277
Cdd:TIGR02169 368 DLRAELE----EVDKEFAETRDELKDYREKLEKlkreinelkreldrlqeelqRLSEELADLNAAIAgieaKINELEEEK 443
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 157824101 1278 EDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSLIAEQQ 1325
Cdd:TIGR02169 444 EDKALEIKKQEWKLEQLAAD-LSKYEQELYDLKEEYDRVEKELSKLQR 490
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
855-1370 |
1.12e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.07 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 855 EITLKEKHQQELQSLKIEYECKLNTLEKDSEE--NVNKILKLKEDLVSLEEALQNKDSEfaiiKHEKDAIVCMQHEKDQK 932
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAEEAKKKADAAKKKAEE----AKKAAEAAKAEAEAAAD 1357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 933 LLEMENimhtQNSEIKELKQSREMV-LEDLKKLHDEKIESlraefqclEQNHLKELEDTlhiRHTEEFEKVITDHKVSLE 1011
Cdd:PTZ00121 1358 EAEAAE----EKAEAAEKKKEEAKKkADAAKKKAEEKKKA--------DEAKKKAEEDK---KKADELKKAAAAKKKADE 1422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1012 KLKKENQQKIDQMLESHAsaiqEKEQQLQELKVKVSDlsdmrcKLEVELALKEAE----TDEIKILLEESRTQQKetlks 1087
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKA----EEAKKADEAKKKAEE------AKKAEEAKKKAEeakkADEAKKKAEEAKKADE----- 1487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1088 lLEQETENLRTEINKLNQKIHDNSESyqvglSELRSLMTIEK-DQCISELISRHEEESNilKAELDSVTALHHQAFEIEK 1166
Cdd:PTZ00121 1488 -AKKKAEEAKKKADEAKKAAEAKKKA-----DEAKKAEEAKKaDEAKKAEEAKKADEAK--KAEEKKKADELKKAEELKK 1559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1167 KLKEQIVElQTKLNSELSALEKQKDEKITQQEEKYKALIQNL-EKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEF 1245
Cdd:PTZ00121 1560 AEEKKKAE-EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQL 1638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1246 KlERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQL--EEQEKRKNEEMQNVRtsliAE 1323
Cdd:PTZ00121 1639 K-KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALkkEAEEAKKAEELKKKE----AE 1713
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 157824101 1324 QqtnfntVLTREKMRKENIINDLsdKLKSTMQQQERDKDLIESLSED 1370
Cdd:PTZ00121 1714 E------KKKAEELKKAEEENKI--KAEEAKKEAEEDKKKAEEAKKD 1752
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1004-1237 |
1.12e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.93 E-value: 1.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1004 TDHKVSLEKLKKENQQKIDQM---LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAEtdeikilLEESRTQ 1080
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELekeLAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE-------LAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1081 QKEtlkslLEQETENLRTEINKLNQKIHDNSE--SYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALH 1158
Cdd:COG4942 92 IAE-----LRAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1159 HQAFEIEKKLKEQIVELQTKLNsELSALEKQKDE---KITQQEEKYKALIQNLEKDKQRLamnheqdkEQLIQKLNFEKD 1235
Cdd:COG4942 167 AELEAERAELEALLAELEEERA-ALEALKAERQKllaRLEKELAELAAELAELQQEAEEL--------EALIARLEAEAA 237
|
..
gi 157824101 1236 EA 1237
Cdd:COG4942 238 AA 239
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
947-1373 |
1.51e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.20 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 947 IKELKQSREMVLEDLKKLHDEKIE-SLRAEFQCLEQNhLKELEDTLH---------IRHTEEFEKVITDHKVSLEKLKkE 1016
Cdd:PRK02224 178 VERVLSDQRGSLDQLKAQIEEKEEkDLHERLNGLESE-LAELDEEIEryeeqreqaRETRDEADEVLEEHEERREELE-T 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1017 NQQKIDQMLESHASAIQEKE---QQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQ-- 1091
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREelaEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrv 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1092 -------ETENLRTEINKL---NQKIHDNSESYQVGLSELRSLMTIEKDQcISEL---ISRHEEESNILKAELDSVTALH 1158
Cdd:PRK02224 336 aaqahneEAESLREDADDLeerAEELREEAAELESELEEAREAVEDRREE-IEELeeeIEELRERFGDAPVDLGNAEDFL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1159 HQAFEIEKKLKEQIVELQTKLNSELSALEKQKD----EKITQ--QEEKYKALIQNLEKDKQRLAmNHEQDKEQLIQKLNf 1232
Cdd:PRK02224 415 EELREERDELREREAELEATLRTARERVEEAEAlleaGKCPEcgQPVEGSPHVETIEEDRERVE-ELEAELEDLEEEVE- 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1233 EKDEAIQTALDEFKLERELveKELLEKVKHLENQIA--------KSPAFESAREDSSSLVAELQEK------LQEEKAKF 1298
Cdd:PRK02224 493 EVEERLERAEDLVEAEDRI--ERLEERREDLEELIAerretieeKRERAEELRERAAELEAEAEEKreaaaeAEEEAEEA 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1299 LEQLEEQEKRKN------EEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLS-DKLKStmqQQERDKDL-------- 1363
Cdd:PRK02224 571 REEVAELNSKLAelkeriESLERIRTLLAAIADAEDEIERLREKREALAELNDERrERLAE---KRERKRELeaefdear 647
|
490
....*....|
gi 157824101 1364 IESLSEDRAR 1373
Cdd:PRK02224 648 IEEAREDKER 657
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
853-1302 |
1.86e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 56.20 E-value: 1.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 853 SLEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQK 932
Cdd:PRK02224 306 DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREE 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 933 LLEMEnimhtqnSEIKELKQSREMVLEDLKKLHDEKiESLRAEFQCLEQNhLKELEDTLhirhtEEFEKVITDHKVSLEK 1012
Cdd:PRK02224 386 IEELE-------EEIEELRERFGDAPVDLGNAEDFL-EELREERDELRER-EAELEATL-----RTARERVEEAEALLEA 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1013 LK-KENQQKIDQmlESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVEL----ALKEAET-----DEIKILLEESRTQQK 1082
Cdd:PRK02224 452 GKcPECGQPVEG--SPHVETIEEDRERVEELEAELEDLEEEVEEVEERLeraeDLVEAEDrierlEERREDLEELIAERR 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1083 ETLKSLLEQeTENLRTEINKLNQKIHDNSESYQvglsELRSlmtiEKDQCISElISRHEEESNILKAELDSVTALHHQAF 1162
Cdd:PRK02224 530 ETIEEKRER-AEELRERAAELEAEAEEKREAAA----EAEE----EAEEAREE-VAELNSKLAELKERIESLERIRTLLA 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1163 EIEkKLKEQIVELQTKLnSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNfEKDEAIQTAL 1242
Cdd:PRK02224 600 AIA-DAEDEIERLREKR-EALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVE-EKLDELREER 676
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157824101 1243 DEFK-----LERELVE-KELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQL 1302
Cdd:PRK02224 677 DDLQaeigaVENELEElEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRNVETLERM 742
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
840-1475 |
1.94e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.30 E-value: 1.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 840 AVEIRNIIDKVKCSLEITLKEKHQQElQSLKIEYECKLNTLEKDSEEnvnkiLKLKEDLVSLEEALQNKDSEFAIIKHEK 919
Cdd:PTZ00121 1196 AEDARKAEAARKAEEERKAEEARKAE-DAKKAEAVKKAEEAKKDAEE-----AKKAEEERNNEEIRKFEEARMAHFARRQ 1269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 920 DAIVCMQHEKDQKLLEMENImhtqnSEIKELKQSREM-VLEDLKKLHDEKieslraefqcleqnhlkeledtlhiRHTEE 998
Cdd:PTZ00121 1270 AAIKAEEARKADELKKAEEK-----KKADEAKKAEEKkKADEAKKKAEEA-------------------------KKADE 1319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 999 FEKVITDHKVSLEKLKK--ENQQKIDQMLESHASAIQEKEQQLQElKVKVSDLSDMRCKLEVELALKEAE----TDEIKI 1072
Cdd:PTZ00121 1320 AKKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEE-KAEAAEKKKEEAKKKADAAKKKAEekkkADEAKK 1398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1073 LLEESRTQQKETLKSLLEQ----ETENLRTEINKLNQKIHDNSESYQVglSELRSlmTIEKDQCISELISRHEEESNILK 1148
Cdd:PTZ00121 1399 KAEEDKKKADELKKAAAAKkkadEAKKKAEEKKKADEAKKKAEEAKKA--DEAKK--KAEEAKKAEEAKKKAEEAKKADE 1474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1149 A-----ELDSVTALHHQAFEIEKKLKE--QIVELQTKLNSELSALEKQKDEKITQQEEKYKA--LIQNLEKDK-QRLAMN 1218
Cdd:PTZ00121 1475 AkkkaeEAKKADEAKKKAEEAKKKADEakKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAdeAKKAEEKKKaDELKKA 1554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1219 HEQDKEQLIQKLNFEKDEAIQTALDEFKLER-ELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAK 1297
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKAEEaKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK 1634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1298 F--LEQLEEQEKRKNEEMQNvrtsliAEQQtnfNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLL 1375
Cdd:PTZ00121 1635 VeqLKKKEAEEKKKAEELKK------AEEE---NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1376 EEKKKLEEEVSKlrtssvlpSAPVLAAPELYGACAPELPGEPERSAmETTDEGRVDSAMETSMMsvQENMLSEEKQRIML 1455
Cdd:PTZ00121 1706 ELKKKEAEEKKK--------AEELKKAEEENKIKAEEAKKEAEEDK-KKAEEAKKDEEEKKKIA--HLKKEEEKKAEEIR 1774
|
650 660
....*....|....*....|
gi 157824101 1456 LERTLQLKEEENKRLNQRLM 1475
Cdd:PTZ00121 1775 KEKEAVIEEELDEEDEKRRM 1794
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1166-1472 |
3.44e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 3.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1166 KKLKEQIVELQ--------TKLNSELSALEKQKDEKiTQQEEKYKALIQNLEKDKQ--RLAMNHEQDKEQLIQKLNFEKD 1235
Cdd:TIGR02168 216 KELKAELRELElallvlrlEELREELEELQEELKEA-EEELEELTAELQELEEKLEelRLEVSELEEEIEELQKELYALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1236 EAIQtaldefKLERELVEKEllEKVKHLENQIAKSPA----FESAREDSSSLVAELQEKLQEEKAKFlEQLEEQEKRKNE 1311
Cdd:TIGR02168 295 NEIS------RLEQQKQILR--ERLANLERQLEELEAqleeLESKLDELAEELAELEEKLEELKEEL-ESLEAELEELEA 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1312 EMQNvRTSLIAEQQTNFNTVltrekmRKEniINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEekkkleeevsklRTS 1391
Cdd:TIGR02168 366 ELEE-LESRLEELEEQLETL------RSK--VAQLELQIASLNNEIERLEARLERLEDRRERLQQ------------EIE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1392 SVLPSAPVLAAPELYGACAPELPGEPERSAMETTDEGRVDSAME-----TSMMSVQENMLSEEKQRIMLLERTLQLKEEE 1466
Cdd:TIGR02168 425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREeleeaEQALDAAERELAQLQARLDSLERLQENLEGF 504
|
....*.
gi 157824101 1467 NKRLNQ 1472
Cdd:TIGR02168 505 SEGVKA 510
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
894-1302 |
4.49e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.84 E-value: 4.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 894 LKEDLVSLEEALQnkdSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTqnseikeLKQSREmvleDLKKLHDEKiESLR 973
Cdd:pfam12128 602 LRERLDKAEEALQ---SAREKQAAAEEQLVQANGELEKASREETFARTA-------LKNARL----DLRRLFDEK-QSEK 666
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 974 AEFQcleqnhlkeledtlhiRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQE-KEQQLQELKVKVSDLSDM 1052
Cdd:pfam12128 667 DKKN----------------KALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREaRTEKQAYWQVVEGALDAQ 730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1053 RCKLEVELALKEAETD-EIKILleesRTQQKETLKSLL--EQETENLRTEINKLNQKIhdnsESYQVGLSELRSLMTIEK 1129
Cdd:pfam12128 731 LALLKAAIAARRSGAKaELKAL----ETWYKRDLASLGvdPDVIAKLKREIRTLERKI----ERIAVRRQEVLRYFDWYQ 802
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1130 DQCISELISRHEEESNILKAELdsvtalhhqafEIEKKLKEQIVELQT---KLNSELSALEKQKDEkITQQEEKYKALIQ 1206
Cdd:pfam12128 803 ETWLQRRPRLATQLSNIERAIS-----------ELQQQLARLIADTKLrraKLEMERKASEKQQVR-LSENLRGLRCEMS 870
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1207 nlekdkqRLAMNHE-QDKEQLIQKLNFEKDeaiqtALDEFKLERELVEKELLEKVKHLENQIAKSPA------FESARED 1279
Cdd:pfam12128 871 -------KLATLKEdANSEQAQGSIGERLA-----QLEDLKLKRDYLSESVKKYVEHFKNVIADHSGsglaetWESLREE 938
|
410 420
....*....|....*....|....
gi 157824101 1280 SSSLVAELQEKLQEEK-AKFLEQL 1302
Cdd:pfam12128 939 DHYQNDKGIRLLDYRKlVPYLEQW 962
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1030-1241 |
5.24e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 53.68 E-value: 5.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1030 SAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEtlkslLEQETENLRTEINKLNQKIHD 1109
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDK-----LQAEIAEAEAEIEERREELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1110 NSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALhhqafeieKKLKEQIVELQTKLNSELSALEKQ 1189
Cdd:COG3883 91 RARALYRSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEEL--------KADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 1190 KDEKITQQEE------KYKALIQNLEKDKQRLamnhEQDKEQLIQKLNFEKDEAIQTA 1241
Cdd:COG3883 163 KAELEAAKAEleaqqaEQEALLAQLSAEEAAA----EAQLAELEAELAAAEAAAAAAA 216
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
928-1320 |
6.60e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 6.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 928 EKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhdEKIESLRAEFQCLEQ--NHLKELEDTLhiRHTEEFEKVITD 1005
Cdd:COG4717 85 EKEEEYAELQEELEELEEELEELEAELEELREELEKL--EKLLQLLPLYQELEAleAELAELPERL--EELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1006 HKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKilleesrtQQKETL 1085
Cdd:COG4717 161 LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE--------EELEQL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1086 KSLLEQEtenlrteinKLNQKIHDNSESYqVGLSELRSLMTIekdqcISELISRHEEESNILKA----------ELDSVT 1155
Cdd:COG4717 233 ENELEAA---------ALEERLKEARLLL-LIAAALLALLGL-----GGSLLSLILTIAGVLFLvlgllallflLLAREK 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1156 ALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKIT------QQEEKYKALIQNLEKDKQRLAMN-HEQDKEQLIQ 1228
Cdd:COG4717 298 ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEellellDRIEELQELLREAEELEEELQLEeLEQEIAALLA 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1229 KLNFEKDEAIQTALDEFKLERelvekELLEKVKHLENQIAKSPAFESAREDSSSLvAELQEKLQEEKAKfLEQLEEQEKR 1308
Cdd:COG4717 378 EAGVEDEEELRAALEQAEEYQ-----ELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEE-LEELEEELEE 450
|
410
....*....|..
gi 157824101 1309 KNEEMQNVRTSL 1320
Cdd:COG4717 451 LREELAELEAEL 462
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
837-1252 |
6.76e-07 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 54.19 E-value: 6.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 837 KCTAVEIRNIIDKVKCSLEITLKEKHQQEL-QSLKIEYECKLNTLEKDSEENVNKIL----------KLKEDLVSLEEAL 905
Cdd:COG5185 143 LDEIADIEASYGEVETGIIKDIFGKLTQELnQNLKKLEIFGLTLGLLKGISELKKAEpsgtvnsikeSETGNLGSESTLL 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 906 QNKDSEFAIIKHEKDAIVCMQHEKDQKLL--EMENIMhTQNSEIKE--LKQSREMVledlKKLhDEKIESLRAEFQCLEQ 981
Cdd:COG5185 223 EKAKEIINIEEALKGFQDPESELEDLAQTsdKLEKLV-EQNTDLRLekLGENAESS----KRL-NENANNLIKQFENTKE 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 982 NhLKELEDTLHIR-HTEEFEKVI--TDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDmrcklEV 1058
Cdd:COG5185 297 K-IAEYTKSIDIKkATESLEEQLaaAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVG-----EV 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1059 ELALKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEINklNQKIHDNSESyqvglselrslmtiEKDQCISELIS 1138
Cdd:COG5185 371 ELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLED--TLKAADRQIE--------------ELQRQIEQATS 434
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1139 RHEEESNILKAELDSVTALHHqafEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMN 1218
Cdd:COG5185 435 SNEEVSKLLNELISELNKVMR---EADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQ 511
|
410 420 430
....*....|....*....|....*....|....
gi 157824101 1219 HEQDKEQLIQKLNFEKDEAIQTALDEFKLERELV 1252
Cdd:COG5185 512 LEGVRSKLDQVAESLKDFMRARGYAHILALENLI 545
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
852-1215 |
6.98e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 54.30 E-value: 6.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 852 CSLEITlkEKHQQELQSlkiEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALqnkdsefaiikhekdaivcmqhEKDQ 931
Cdd:PRK03918 441 CGRELT--EEHRKELLE---EYTAELKRIEKELKEIEEKERKLRKELRELEKVL----------------------KKES 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 932 KLLEMENIMhtqnSEIKELKQSREMV-LEDLKKlHDEKIESLRAEFQCLEQNhLKELEDTLhiRHTEEFEKVITDHKVSL 1010
Cdd:PRK03918 494 ELIKLKELA----EQLKELEEKLKKYnLEELEK-KAEEYEKLKEKLIKLKGE-IKSLKKEL--EKLEELKKKLAELEKKL 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1011 EKLKKENQQKIDQMLESHASAIQEKEQQLQEL-------------KVKVSDLSDMRCKLEVELALKEAETDEIKILLEES 1077
Cdd:PRK03918 566 DELEEELAELLKELEELGFESVEELEERLKELepfyneylelkdaEKELEREEKELKKLEEELDKAFEELAETEKRLEEL 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1078 RTQQKETLKSLLEQETENLRTEINKLNQKIhdnsESYQVGLSELRSLM-----TIEKDQCISELISRHEEESNILKAELD 1152
Cdd:PRK03918 646 RKELEELEKKYSEEEYEELREEYLELSREL----AGLRAELEELEKRReeikkTLEKLKEELEEREKAKKELEKLEKALE 721
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157824101 1153 SVTALHHQAFEIEKKLKEQIVELQTKLNSELSalekqkdEKITqqEEKYKALIQNLEKDKQRL 1215
Cdd:PRK03918 722 RVEELREKVKKYKALLKERALSKVGEIASEIF-------EELT--EGKYSGVRVKAEENKVKL 775
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
864-1272 |
7.16e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 53.97 E-value: 7.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 864 QELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiiKHEKDAIvcmQHEKDQKLLEMEnimhtQ 943
Cdd:pfam17380 247 EDVTTMTPEYTVRYNGQTMTENEFLNQLLHIVQHQKAVSERQQQEKFE----KMEQERL---RQEKEEKAREVE-----R 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 944 NSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKvSLEKLKKENQQK--- 1020
Cdd:pfam17380 315 RRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMR-ELERLQMERQQKner 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1021 IDQMLES-HASAIQEKEQQLQELKVKVsdlsdmrcklevelalkeaETDEIKILLEESRTQQKETLKSLLEQETENLRTE 1099
Cdd:pfam17380 394 VRQELEAaRKVKILEEERQRKIQQQKV-------------------EMEQIRAEQEEARQREVRRLEEERAREMERVRLE 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1100 INKLNQKIhdnsesyqvglselrslmtiekdqcisELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKl 1179
Cdd:pfam17380 455 EQERQQQV---------------------------ERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQ- 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1180 nselSALEKQKDEKITQQE--EKYKALIQnlekDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELL 1257
Cdd:pfam17380 507 ----AMIEEERKRKLLEKEmeERQKAIYE----EERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMM 578
|
410
....*....|....*
gi 157824101 1258 EKVKHLENQIAKSPA 1272
Cdd:pfam17380 579 RQIVESEKARAEYEA 593
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
937-1370 |
7.25e-07 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 54.45 E-value: 7.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 937 ENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFqcleqNHLKELEDTLH-IRHTEEFEKVITDHKVSLEKLKK 1015
Cdd:PTZ00440 420 EDVLKENSQKIADYALYSNLEIIEIKKKYDEKINELKKSI-----NQLKTLISIMKsFYDLIISEKDSMDSKEKKESSDS 494
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1016 ENQQKIDQML------ESHASAIQEKEQQLQELKVKVSDLsdmrcKLEVELALKEAETDEIKILLEESRTQQKETLKSLL 1089
Cdd:PTZ00440 495 NYQEKVDELLqiinsiKEKNNIVNNNFKNIEDYYITIEGL-----KNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDI 569
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1090 EQETENLRTEINKLNQKIHDNSESYQV--GLSELRSLMTIEKDQCISELISRHEEESNI--------LKAELDSVTAL-- 1157
Cdd:PTZ00440 570 KNKIKYIEENVDHIKDIISLNDEIDNIiqQIEELINEALFNKEKFINEKNDLQEKVKYIlnkfykgdLQELLDELSHFld 649
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1158 HHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLA-MNHEQDKEQLIQKLN--FEK 1234
Cdd:PTZ00440 650 DHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMKSDNIDNIIKNLKKELQNLLSLKENIIkKQLNNIEQDISNSLNqyTIK 729
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1235 DEAIQTALDEFKlerelVEKELLEKVKHLENQIakspafesaredssslvaelqeklqeeKAKFLEQLEEQEKR------ 1308
Cdd:PTZ00440 730 YNDLKSSIEEYK-----EEEEKLEVYKHQIINR---------------------------KNEFILHLYENDKDlpdgkn 777
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 1309 -KNEEMQNVRTSLIAEQQTNFNTVLTRE--KMRKENI--INDLSDKLKS-TMQQQERDKDLIESLSED 1370
Cdd:PTZ00440 778 tYEEFLQYKDTILNKENKISNDINILKEnkKNNQDLLnsYNILIQKLEAhTEKNDEELKQLLQKFPTE 845
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
854-1373 |
7.79e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.89 E-value: 7.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 854 LEITLKEKHQQELQSLKIEYECKLNTLEKD---SEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDaivcmqhEKD 930
Cdd:PRK02224 192 LKAQIEEKEEKDLHERLNGLESELAELDEEierYEEQREQARETRDEADEVLEEHEERREELETLEAEIE-------DLR 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 931 QKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEkieslrAEFQCLEQNHLKELEDTLHIRHtEEFEKVITDHKVSL 1010
Cdd:PRK02224 265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAE------AGLDDADAEAVEARREELEDRD-EELRDRLEECRVAA 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1011 EKLKKE---NQQKIDQmLESHASAIQEK----EQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEES---RTQ 1080
Cdd:PRK02224 338 QAHNEEaesLREDADD-LEERAEELREEaaelESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAedfLEE 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1081 QKETLKSLLEQETEnLRTEINKLNQKIHDNSESYQVG--------LSELRSLMTIEKDQcisELISRHEEESNILKAELD 1152
Cdd:PRK02224 417 LREERDELREREAE-LEATLRTARERVEEAEALLEAGkcpecgqpVEGSPHVETIEEDR---ERVEELEAELEDLEEEVE 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1153 SVTALHHQAfeieKKLKEQIVELQTKLNsELSALEKQKDEKITQQEEKYKAlIQNLEKDKQRLAMNHEQdKEQLIQKLNF 1232
Cdd:PRK02224 493 EVEERLERA----EDLVEAEDRIERLEE-RREDLEELIAERRETIEEKRER-AEELRERAAELEAEAEE-KREAAAEAEE 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1233 EKDEAIQTALDefkLERELVE-KELLEKVKHLENQIAkspafesAREDSSSLVAELQEKLQEekakfLEQLEEQEKRKNE 1311
Cdd:PRK02224 566 EAEEAREEVAE---LNSKLAElKERIESLERIRTLLA-------AIADAEDEIERLREKREA-----LAELNDERRERLA 630
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157824101 1312 EMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLkstmqqqerdkdliESLSEDRAR 1373
Cdd:PRK02224 631 EKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKL--------------DELREERDD 678
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
853-1371 |
1.78e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 52.90 E-value: 1.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 853 SLEITLKEKhQQELQSLKIEYECKlNTLEKDSEEN--VNKILKLKE-DLVSLEEALQNKDSEFAIIKHEKDaIVCMQHEK 929
Cdd:pfam10174 196 HLEVLLDQK-EKENIHLREELHRR-NQLQPDPAKTkaLQTVIEMKDtKISSLERNIRDLEDEVQMLKTNGL-LHTEDREE 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 930 DQKLLE--------MENIMHTQNSEIKelKQSREMV-----LEDLK------KLHDEKI-ESLRAEFQclEQNHLKELED 989
Cdd:pfam10174 273 EIKQMEvykshskfMKNKIDQLKQELS--KKESELLalqtkLETLTnqnsdcKQHIEVLkESLTAKEQ--RAAILQTEVD 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 990 TLHIRhTEEFEKVITDHKVSLEKLKKEN------------------------QQKIDQMLEShasaIQEKEQQLQELKVK 1045
Cdd:pfam10174 349 ALRLR-LEEKESFLNKKTKQLQDLTEEKstlageirdlkdmldvkerkinvlQKKIENLQEQ----LRDKDKQLAGLKER 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1046 VSDLSDMRCKLEVELA-LKEAETDEIKILleESRTQQKETLKSLLEQETENLRTEINKLNQKihdnsesyqvgLSELRSL 1124
Cdd:pfam10174 424 VKSLQTDSSNTDTALTtLEEALSEKERII--ERLKEQREREDRERLEELESLKKENKDLKEK-----------VSALQPE 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1125 MTiEKDQCISELisrHEEESNILKAELDSVTALHHQAFEIEKKlKEQIVELQTKLnselsaLEKQKDEKITQQEEKYKAL 1204
Cdd:pfam10174 491 LT-EKESSLIDL---KEHASSLASSGLKKDSKLKSLEIAVEQK-KEECSKLENQL------KKAHNAEEAVRTNPEINDR 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1205 IQNLEKDKQRLAmnHEQDKEQliqklnfEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIakspafesarEDSSSLV 1284
Cdd:pfam10174 560 IRLLEQEVARYK--EESGKAQ-------AEVERLLGILREVENEKNDKDKKIAELESLTLRQM----------KEQNKKV 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1285 AELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEqqtnfnTVLTREKMRKEniINDLSDKLKSTMQQ-QERDKDL 1363
Cdd:pfam10174 621 ANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEE------LMGALEKTRQE--LDATKARLSSTQQSlAEKDGHL 692
|
....*...
gi 157824101 1364 iESLSEDR 1371
Cdd:pfam10174 693 -TNLRAER 699
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
896-1308 |
2.17e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 52.20 E-value: 2.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 896 EDLVSLEEALQNKDSEFAIIKHEKDAIVcMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIEsLRAE 975
Cdd:pfam07888 4 DELVTLEEESHGEEGGTDMLLVVPRAEL-LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRE-LESR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 976 FQCLEQN--HLKELEDTLHIRHTEE--FEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQ---EKEQQLQELKVKVSD 1048
Cdd:pfam07888 82 VAELKEElrQSREKHEELEEKYKELsaSSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQrvlERETELERMKERAKK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1049 LSDMRCKLEVElalKEAETDEIKILLEESRTQQKE--TLKSLLEQ---ETENLRTEINKLNQKI---HDNSESYQVGLSE 1120
Cdd:pfam07888 162 AGAQRKEEEAE---RKQLQAKLQQTEEELRSLSKEfqELRNSLAQrdtQVLQLQDTITTLTQKLttaHRKEAENEALLEE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1121 LRSLmtiekdqciSELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALekqKDEKITQQEEK 1200
Cdd:pfam07888 239 LRSL---------QERLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLAL---REGRARWAQER 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1201 yKALIQNLEKDKQRlamnheqdkeqlIQKLNFEKdEAIQTALDEFKLERELVEKEL-LEKVKhleNQIAKSPAFESARED 1279
Cdd:pfam07888 307 -ETLQQSAEADKDR------------IEKLSAEL-QRLEERLQEERMEREKLEVELgREKDC---NRVQLSESRRELQEL 369
|
410 420 430
....*....|....*....|....*....|.
gi 157824101 1280 SSSLVAELQEK--LQEEKAKFLEQLEEQEKR 1308
Cdd:pfam07888 370 KASLRVAQKEKeqLQAEKQELLEYIRQLEQR 400
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
860-1326 |
2.34e-06 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 52.77 E-value: 2.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 860 EKHQQELQSLKIEYEcKLNTLEKDSEENVNKILKLKEDLVSLE----EALQNKDSEFAIIKHEKDAIVcmQHEKDQKLLE 935
Cdd:COG5022 878 ELAERQLQELKIDVK-SISSLKLVNLELESEIIELKKSLSSDLienlEFKTELIARLKKLLNNIDLEE--GPSIEYVKLP 954
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 936 MENIMHTQNSEIKELKQSREMVLEDLKKLHDEKI----ESLR-----AEFQCLE---QNHLKELEDTLHI--RHTEEFEK 1001
Cdd:COG5022 955 ELNKLHEVESKLKETSEEYEDLLKKSTILVREGNkansELKNfkkelAELSKQYgalQESTKQLKELPVEvaELQSASKI 1034
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1002 VITDHKvSLEKLKKENQQKIDQMLEshasaIQEKEQQLQELKVKVSDLSDMRCKLE----VELALKEAETDEIKILLEES 1077
Cdd:COG5022 1035 ISSEST-ELSILKPLQKLKGLLLLE-----NNQLQARYKALKLRRENSLLDDKQLYqlesTENLLKTINVKDLEVTNRNL 1108
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1078 RTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTAL 1157
Cdd:COG5022 1109 VKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALY 1188
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1158 ---HHQAFEIEKKLKEQIVELQTKLNSELSALEKQKD---EKITQQEEKYK---ALIQNLEKDKQRlamnhEQDKEQLIQ 1228
Cdd:COG5022 1189 dekSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKlisEGWVPTEYSTSlkgFNNLNKKFDTPA-----SMSNEKLLS 1263
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1229 KLNfekdeaiqtaLDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAkfleqlEEQEKR 1308
Cdd:COG5022 1264 LLN----------SIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATEVNYNSE------ELDDWC 1327
|
490
....*....|....*...
gi 157824101 1309 KNEEMQNVRTSLIAEQQT 1326
Cdd:COG5022 1328 REFEISDVDEELEELIQA 1345
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
928-1471 |
2.40e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.66 E-value: 2.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 928 EKDQKLLEMEnimhtqnsEIKELKQSREMVLEDLKKLHDeKIESLRAEFQCLEQnhlkeledtlhirHTEEFEKVITDHK 1007
Cdd:TIGR00618 164 EKKELLMNLF--------PLDQYTQLALMEFAKKKSLHG-KAELLTLRSQLLTL-------------CTPCMPDTYHERK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1008 VSLEKLKKENQQKIDQMLESHASAIQEKEQQ---------LQELKVKVSDLSDMRCKLE-----VELALKEAETDEIKIL 1073
Cdd:TIGR00618 222 QVLEKELKHLREALQQTQQSHAYLTQKREAQeeqlkkqqlLKQLRARIEELRAQEAVLEetqerINRARKAAPLAAHIKA 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1074 LEESRTQQKETLKSLleQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEkdqcisELISRHEEESNILKAELDS 1153
Cdd:TIGR00618 302 VTQIEQQAQRIHTEL--QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE------IHIRDAHEVATSIREISCQ 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1154 VTALHHQAfeieKKLKEQIVELQTKLNSelsalekQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFE 1233
Cdd:TIGR00618 374 QHTLTQHI----HTLQQQKTTLTQKLQS-------LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAEL 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1234 KDEAIQTALDEFKLeRELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAkfleQLEEQEKRKNEEM 1313
Cdd:TIGR00618 443 CAAAITCTAQCEKL-EKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPC----PLCGSCIHPNPAR 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1314 QNvrtSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLR--TS 1391
Cdd:TIGR00618 518 QD---IDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQniTV 594
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1392 SVLPSAPVLAAPELYGACAP---ELPGEPERSAMETTDEGRVDS---AMETSMMSVQENMLSEEKQRIMLLERTLQLKEE 1465
Cdd:TIGR00618 595 RLQDLTEKLSEAEDMLACEQhalLRKLQPEQDLQDVRLHLQQCSqelALKLTALHALQLTLTQERVREHALSIRVLPKEL 674
|
....*.
gi 157824101 1466 ENKRLN 1471
Cdd:TIGR00618 675 LASRQL 680
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1076-1326 |
3.30e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 51.37 E-value: 3.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1076 ESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekdqciselisrhEEESNILKAELDSVT 1155
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEAL----------------QAEIDKLQAEIAEAE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1156 AlhhqafEIEKK---LKEQIVELQTK--LNSELSALEKQKD--------EKITQQEEKYKALIQNLEKDKQRLamnhEQD 1222
Cdd:COG3883 79 A------EIEERreeLGERARALYRSggSVSYLDVLLGSESfsdfldrlSALSKIADADADLLEELKADKAEL----EAK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1223 KEQLIQKLNfekdeaiqtaldefklERELVEKELLEKVKHLENQIAKspafesaREDSSSLVAELQEKLQEEKAKFLEQL 1302
Cdd:COG3883 149 KAELEAKLA----------------ELEALKAELEAAKAELEAQQAE-------QEALLAQLSAEEAAAEAQLAELEAEL 205
|
250 260
....*....|....*....|....
gi 157824101 1303 EEQEKRKNEEMQNVRTSLIAEQQT 1326
Cdd:COG3883 206 AAAEAAAAAAAAAAAAAAAAAAAA 229
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
790-1475 |
3.64e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.89 E-value: 3.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 790 RAALHVQLEKCRVaaQDSHISIQTIKDDLCHFRTfVQKEQCDLSNYL--KCTAVEIRNIIDKVKCSLEITLKEKHQQ--- 864
Cdd:TIGR00618 202 RSQLLTLCTPCMP--DTYHERKQVLEKELKHLRE-ALQQTQQSHAYLtqKREAQEEQLKKQQLLKQLRARIEELRAQeav 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 865 -ELQSLKIEYECKLNTLEKDSEenvnKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIV------CMQHEKDQKLLEME 937
Cdd:TIGR00618 279 lEETQERINRARKAAPLAAHIK----AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVkqqssiEEQRRLLQTLHSQE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 938 NIMHTQNSEIKELKQSREMVLEDLKKLH--DEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKlKK 1015
Cdd:TIGR00618 355 IHIRDAHEVATSIREISCQQHTLTQHIHtlQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKK-QQ 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1016 ENQQKIDQMLESHAsaiqekEQQLQELKVKVSDLSDMRCKLEvelALKEAETDEIKILLEESRTQQKETLKSLLEQETEN 1095
Cdd:TIGR00618 434 ELQQRYAELCAAAI------TCTAQCEKLEKIHLQESAQSLK---EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPC 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1096 LRTEinklnQKIHDNSESYQVGLS------------ELRSLMTIEKD---QCISEL--ISRHEEESNILKAELDSVTALH 1158
Cdd:TIGR00618 505 PLCG-----SCIHPNPARQDIDNPgpltrrmqrgeqTYAQLETSEEDvyhQLTSERkqRASLKEQMQEIQQSFSILTQCD 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1159 HQAFEIEKKLKEQIVELQtKLNSELSALEKQKDEKITQQEEKykaliQNLEKDKQRLAMnHEQDKEQLIQKLNFEKdEAI 1238
Cdd:TIGR00618 580 NRSKEDIPNLQNITVRLQ-DLTEKLSEAEDMLACEQHALLRK-----LQPEQDLQDVRL-HLQQCSQELALKLTAL-HAL 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1239 QTALDEFKLERELVEKELLEKVKHLENQiAKSPAFESAREDSSSLVAELQEKLqeEKAKFLEQLEEQEKRKNEEMQNVRT 1318
Cdd:TIGR00618 652 QLTLTQERVREHALSIRVLPKELLASRQ-LALQKMQSEKEQLTYWKEMLAQCQ--TLLRELETHIEEYDREFNEIENASS 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1319 SLIAEQQTNFNTVltrekmrkENIINDLSDKLKSTMQQQERD---KDLIESLSEDRARLLEEKKKLEEEVSKLRTSSVLP 1395
Cdd:TIGR00618 729 SLGSDLAAREDAL--------NQSLKELMHQARTVLKARTEAhfnNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHL 800
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1396 SAPVLAAPELYgacAPElpGEPERSAMETTDEGRVDsametsmmsvQENMLSEEKQRIMLLERTLQLKEEENKRLNQRLM 1475
Cdd:TIGR00618 801 LKTLEAEIGQE---IPS--DEDILNLQCETLVQEEE----------QFLSRLEEKSATLGEITHQLLKYEECSKQLAQLT 865
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1156-1311 |
3.91e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 3.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1156 ALHHQAFEIEKKLKE---QIVELQTKLNSELSALEKQKDEKitqqeEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNF 1232
Cdd:COG1579 14 ELDSELDRLEHRLKElpaELAELEDELAALEARLEAAKTEL-----EDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157824101 1233 EKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1311
Cdd:COG1579 89 KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
993-1343 |
7.53e-06 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 50.71 E-value: 7.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 993 IRHTEEFEKVITDhKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQelkVKVSDLSDMRCKLEVELALKEAETDEIKi 1072
Cdd:pfam15818 24 TQYEEQIGKIIVE-TQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQ---MKMCALEEEKGKYQLATEIKEKEIEGLK- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1073 lleesrtqqkETLKSLlEQETENLRTEINKLNQKIHDN---SESYQVGLSELRSLMT----------------------- 1126
Cdd:pfam15818 99 ----------ETLKAL-QVSKYSLQKKVSEMEQKLQLHllaKEDHHKQLNEIEKYYAtitgqfglvkenhgkleqnvqea 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1127 IEKDQCISELISRHEEESNILKAELDSVTA--------LHHQAFE--IEKKLKEQ-IVELQTKLNSELsALEKQKDEKIT 1195
Cdd:pfam15818 168 IQLNKRLSALNKKQESEICSLKKELKKVTSdlikskvtCQYKMGEenINLTIKEQkFQELQERLNMEL-ELNKKINEEIT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1196 Q-QEEKYKALI--QNLEKDKQRLAM-NHEQDKEQLIQKLNFekdeaiQTALDEFKLERELVeKELLEKVKHLENQ----- 1266
Cdd:pfam15818 247 HiQEEKQDIIIsfQHMQQLLQQQTQaNTEMEAELKALKENN------QTLERDNELQREKV-KENEEKFLNLQNEhekal 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1267 -IAKSPAFESARE-----DSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVrtsliaeqqTNFNTVLTREKMrkE 1340
Cdd:pfam15818 320 gTWKKHVEELNGEineikNELSSLKETHIKLQEHYNKLCNQKKFEEDKKFQNVPEV---------NNENSEMSTEKS--E 388
|
...
gi 157824101 1341 NII 1343
Cdd:pfam15818 389 NLI 391
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
858-1106 |
8.30e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.79 E-value: 8.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 858 LKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEME 937
Cdd:TIGR04523 423 LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLN 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 938 NIMHTQNSEIKELKQSREMVLEDLKKLHDEKIEslraefqclEQNHLKELEDTLHirhTEEFEKvitdHKVSLEKLKKEN 1017
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLKEKIEKLESEKKE---------KESKISDLEDELN---KDDFEL----KKENLEKEIDEK 566
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1018 QQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESR--TQQKETLKSL---LEQE 1092
Cdd:TIGR04523 567 NKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEklSSIIKNIKSKknkLKQE 646
|
250
....*....|....
gi 157824101 1093 TENLRTEINKLNQK 1106
Cdd:TIGR04523 647 VKQIKETIKEIRNK 660
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1077-1373 |
1.39e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.74 E-value: 1.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1077 SRTQQKETLKSLleqETENLRTEinkLNQKIHDNSESYQVGLSELRSLMTIEKDQCIselISRHEEESNILKAELDSVTa 1156
Cdd:pfam17380 285 SERQQQEKFEKM---EQERLRQE---KEEKAREVERRRKLEEAEKARQAEMDRQAAI---YAEQERMAMERERELERIR- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1157 LHHQAFEIEKKLKEQI-VELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKD 1235
Cdd:pfam17380 355 QEERKRELERIRQEEIaMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1236 EAIQTALDEFKLERELVEKELLEKVKHLEnQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQN 1315
Cdd:pfam17380 435 REVRRLEEERAREMERVRLEEQERQQQVE-RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEER 513
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 1316 VRTSLIAEQQTNFNTVLTREKMRKEniinDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:pfam17380 514 KRKLLEKEMEERQKAIYEEERRREA----EEERRKQQEMEERRRIQEQMRKATEERSR 567
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1074-1323 |
1.43e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.91 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1074 LEESRTQQK--------ETLKSLlEQETENLRTEINKLnQKIHDNSESYQVGLSELRSLmtiekDQCISEL-ISRHEEES 1144
Cdd:COG4913 218 LEEPDTFEAadalvehfDDLERA-HEALEDAREQIELL-EPIRELAERYAAARERLAEL-----EYLRAALrLWFAQRRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1145 NILKAELDSVTALHHQAFEIEKKLKEQIVELQTklnsELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQdke 1224
Cdd:COG4913 291 ELLEAELEELRAELARLEAELERLEARLDALRE----ELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR--- 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1225 qliqklnfekdeaIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESA-REDSSSLVAELQEkLQEEKAKFLEQLE 1303
Cdd:COG4913 364 -------------LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEAlEEALAEAEAALRD-LRRELRELEAEIA 429
|
250 260
....*....|....*....|...
gi 157824101 1304 EQEKRKN---EEMQNVRTSLIAE 1323
Cdd:COG4913 430 SLERRKSnipARLLALRDALAEA 452
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1164-1361 |
1.44e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1164 IEKKLKEQIVELQTK-------LNSELSALEKQKDEkITQQEEKYKALIQNLEKDKQRLAMNhEQDKEQLIQKLNF-EKD 1235
Cdd:COG4717 47 LLERLEKEADELFKPqgrkpelNLKELKELEEELKE-AEEKEEEYAELQEELEELEEELEEL-EAELEELREELEKlEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1236 EAIQTALDEFK-LERELveKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1314
Cdd:COG4717 125 LQLLPLYQELEaLEAEL--AELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 157824101 1315 NVRTSlIAEQQTNFNTvLTREKMRKENIINDLSDKLKSTMQQQERDK 1361
Cdd:COG4717 203 ELQQR-LAELEEELEE-AQEELEELEEELEQLENELEAAALEERLKE 247
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1064-1389 |
1.48e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 1.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1064 EAETDEIKILLeeSRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESyqvgLSELRSLmtIEKDQCISELISRHEEE 1143
Cdd:PRK03918 175 KRRIERLEKFI--KRTENIEELIKEKEKELEEVLREINEISSELPELREE----LEKLEKE--VKELEELKEEIEELEKE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1144 SNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLnSELSALEKQKDEKITQQE--EKYKALIQNLEKDKQRLamnheq 1221
Cdd:PRK03918 247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV-KELKELKEKAEEYIKLSEfyEEYLDELREIEKRLSRL------ 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1222 dkEQLIqklnfekdEAIQTALDEF-KLERELveKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQ----EKLQEEKA 1296
Cdd:PRK03918 320 --EEEI--------NGIEERIKELeEKEERL--EELKKKLKELEKRLEELEERHELYEEAKAKKEELErlkkRLTGLTPE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1297 KFLEQLEEQEKRKNEEMQNVRTsliaeqqtnfntvLTREKMRKENIINDLSD---KLKSTMQQ---------QERDKDLI 1364
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISK-------------ITARIGELKKEIKELKKaieELKKAKGKcpvcgreltEEHRKELL 454
|
330 340
....*....|....*....|....*
gi 157824101 1365 ESLSEDRARLLEEKKKLEEEVSKLR 1389
Cdd:PRK03918 455 EEYTAELKRIEKELKEIEEKERKLR 479
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
849-1349 |
1.51e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 50.05 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 849 KVKCSLEITLKEKHQQELQS-LKIEYECKLN------TLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIK----- 916
Cdd:TIGR01612 525 IIGFDIDQNIKAKLYKEIEAgLKESYELAKNwkklihEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINklkle 604
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 917 -HEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKEL-KQSREMVLEDLKKlHDEKIESLRAEFQCLEQNHLKELEDTLH-- 992
Cdd:TIGR01612 605 lKEKIKNISDKNEYIKKAIDLKKIIENNNAYIDELaKISPYQVPEHLKN-KDKIYSTIKSELSKIYEDDIDALYNELSsi 683
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 993 -----IRHTEEFEKvITDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVkvsdlsDMRCKLEVELalkeaeT 1067
Cdd:TIGR01612 684 vkenaIDNTEDKAK-LDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIV------EIKKHIHGEI------N 750
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1068 DEIKILLEESRTQQKETLKSLLEQETENlrTEINKLNQKI-----HDNSESYQVGLSELRSLMTIEKDQCISELISRHEE 1142
Cdd:TIGR01612 751 KDLNKILEDFKNKEKELSNKINDYAKEK--DELNKYKSKIseiknHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKED 828
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1143 ES----NILKAELDSVTALHHQAFEIEKKLKEQI-------VELQTKLNSELSalekqkDEKITQQEEKY---KALIQNL 1208
Cdd:TIGR01612 829 EIfkiiNEMKFMKDDFLNKVDKFINFENNCKEKIdseheqfAELTNKIKAEIS------DDKLNDYEKKFndsKSLINEI 902
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1209 EKdkqrlAMNHEQDKEQLIQKLN--FEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSsslvae 1286
Cdd:TIGR01612 903 NK-----SIEEEYQNINTLKKVDeyIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNT------ 971
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157824101 1287 LQEKLQEEKAKFLE-QLEEQEKRKNEEMQNVrTSLIAEQQTNFNTVLTREKMRKENIINDLSDK 1349
Cdd:TIGR01612 972 LIDKINELDKAFKDaSLNDYEAKNNELIKYF-NDLKANLGKNKENMLYHQFDEKEKATNDIEQK 1034
|
|
| CCDC73 |
pfam15818 |
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ... |
881-1311 |
2.20e-05 |
|
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.
Pssm-ID: 464893 [Multi-domain] Cd Length: 1048 Bit Score: 49.56 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 881 EKDSEENVNKILKLKEDLVSLEEALQNKDSefAIIKHEKDAIVCMQHEKDQKL--LEMENIMHTQNSEIKElkQSREMVL 958
Cdd:pfam15818 23 ETQYEEQIGKIIVETQELKWQKETLQNQKE--TLAKQHKEAMAVFKKQLQMKMcaLEEEKGKYQLATEIKE--KEIEGLK 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 959 EDLKKLHDEKIeSLRAEFQCLEQN---HLKELEDtlHIRHTEEFEK---VITDH----KVSLEKLKKENQQKIDqmLESH 1028
Cdd:pfam15818 99 ETLKALQVSKY-SLQKKVSEMEQKlqlHLLAKED--HHKQLNEIEKyyaTITGQfglvKENHGKLEQNVQEAIQ--LNKR 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1029 ASAIQEKEQQ-----LQELKVKVSDLsdMRCKLEVELALKEaetDEIKILLEESRTQQKetlkslleQETENLRTEIN-K 1102
Cdd:pfam15818 174 LSALNKKQESeicslKKELKKVTSDL--IKSKVTCQYKMGE---ENINLTIKEQKFQEL--------QERLNMELELNkK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1103 LNQKIHDNSESYQVGLSELrslmtiekdQCISELISRHEEESNILKAELdsvtalhhqafeieKKLKEQivelqtklNSE 1182
Cdd:pfam15818 241 INEEITHIQEEKQDIIISF---------QHMQQLLQQQTQANTEMEAEL--------------KALKEN--------NQT 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1183 LSALEKQKDEKITQQEEKYkaliQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLER---ELVEKELLEK 1259
Cdd:pfam15818 290 LERDNELQREKVKENEEKF----LNLQNEHEKALGTWKKHVEELNGEINEIKNELSSLKETHIKLQEhynKLCNQKKFEE 365
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 157824101 1260 VKHLEN-QIAKSPAFESAREDSSSLVAE----LQEKLQEEKAKFLEQLEEQEKRKNE 1311
Cdd:pfam15818 366 DKKFQNvPEVNNENSEMSTEKSENLIIQkynsEQEIREENTKSFCSDTEYRETEKKK 422
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
814-1390 |
2.56e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 49.28 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 814 IKDDLCH--FRTFVQKEQCDLSNYLKCTAVEIRNIIDKVkcsleitlkEKHQQELQSLKI-------EYECKLNTLEKDS 884
Cdd:TIGR01612 1089 IKEKLKHynFDDFGKEENIKYADEINKIKDDIKNLDQKI---------DHHIKALEEIKKksenyidEIKAQINDLEDVA 1159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 885 E-----ENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIvcmqhEKDQKLLEME---NIMHTQN------SEIKEL 950
Cdd:TIGR01612 1160 DkaisnDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEI-----EKDKTSLEEVkgiNLSYGKNlgklflEKIDEE 1234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 951 KQSREMVLEDLKK----LHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITdhkvsleklKKENQQKIdqmle 1026
Cdd:TIGR01612 1235 KKKSEHMIKAMEAyiedLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHII---------SKKHDENI----- 1300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1027 shaSAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRT---------------QQKETLKSLlEQ 1091
Cdd:TIGR01612 1301 ---SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANiynilklnkikkiidEVKEYTKEI-EE 1376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1092 ETENLRTEINK---LNQKIHDNSeSYQVGLSELRSLMtieKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKL 1168
Cdd:TIGR01612 1377 NNKNIKDELDKsekLIKKIKDDI-NLEECKSKIESTL---DDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENV 1452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1169 KEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEK--------DKQRLAMNH-----EQDKEQLIQKLNFEKD 1235
Cdd:TIGR01612 1453 LLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHIDKskgckdeaDKNAKAIEKnkelfEQYKKDVTELLNKYSA 1532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1236 EAIQTALDEFKLERELVEKEllekVKHLENQIakspafesaredssSLVAELQE----KLQEEKAKFLEQLEEQEKrKNE 1311
Cdd:TIGR01612 1533 LAIKNKFAKTKKDSEIIIKE----IKDAHKKF--------------ILEAEKSEqkikEIKKEKFRIEDDAAKNDK-SNK 1593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1312 EMQNVRTSL---------IAEQQTNFNTVLTREKMRKENI----INDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEK 1378
Cdd:TIGR01612 1594 AAIDIQLSLenfenkflkISDIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDKK 1673
|
650
....*....|..
gi 157824101 1379 KKLEEEVSKLRT 1390
Cdd:TIGR01612 1674 KELDELDSEIEK 1685
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1010-1373 |
2.60e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.00 E-value: 2.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1010 LEKLKKENQQKIDQmLESHASAIQEKEQQLQELKVKVSDLSDM---------RCKLEVELALKEAETDEIKILLEESRTQ 1080
Cdd:COG4717 83 AEEKEEEYAELQEE-LEELEEELEELEAELEELREELEKLEKLlqllplyqeLEALEAELAELPERLEELEERLEELREL 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1081 QKEtlKSLLEQETENLRTEINKLNQK--------IHDNSESYQVGLSELRSLmtiekdqciSELISRHEEESNILKAELD 1152
Cdd:COG4717 162 EEE--LEELEAELAELQEELEELLEQlslateeeLQDLAEELEELQQRLAEL---------EEELEEAQEELEELEEELE 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1153 SVTALhHQAFEIEKKLKEQIVELqtKLNSELSALEKQKDEKITQQEEKYKAL--------IQNLEKDKQRLAMNHEQDKE 1224
Cdd:COG4717 231 QLENE-LEAAALEERLKEARLLL--LIAAALLALLGLGGSLLSLILTIAGVLflvlgllaLLFLLLAREKASLGKEAEEL 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1225 QLIQKLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDS--SSLVAELQEKLQEEKAKFLEQL 1302
Cdd:COG4717 308 QALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELqlEELEQEIAALLAEAGVEDEEEL 387
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157824101 1303 EEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENiINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:COG4717 388 RAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD-EEELEEELEELEEELEELEEELEELREELAE 457
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
773-1370 |
2.66e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 773 SRRMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHISIQTIKDDLCHFRTFVQKEQCDLSNYLKCTAVEIRNIIDKVKC 852
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 853 SLEitLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQK 932
Cdd:TIGR02169 309 SIA--EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 933 LLEMENIMHTQNSEIKELKQSREMVLEDLKKLHdEKIESLRAEFQCLEQNHlKELEDTLhirhteefekvitdhKVSLEK 1012
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLS-EELADLNAAIAGIEAKI-NELEEEK---------------EDKALE 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1013 LKKENQQkidqmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKE--------- 1083
Cdd:TIGR02169 450 IKKQEWK-----LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvh 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1084 -TLKSLLEQE-----------------------------TENLRTE---------INKLNQKIHDNSESYQVG------- 1117
Cdd:TIGR02169 525 gTVAQLGSVGeryataievaagnrlnnvvveddavakeaIELLKRRkagratflpLNKMRDERRDLSILSEDGvigfavd 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1118 ------------------------LSELRSLM------TIEKD-----------------------------QCISELIS 1138
Cdd:TIGR02169 605 lvefdpkyepafkyvfgdtlvvedIEAARRLMgkyrmvTLEGElfeksgamtggsraprggilfsrsepaelQRLRERLE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1139 RHEEESNILKAELDSVTALHHQAF-----------EIEK----------KLKEQIVELQTKLNSELSALEKQKDE----- 1192
Cdd:TIGR02169 685 GLKRELSSLQSELRRIENRLDELSqelsdasrkigEIEKeieqleqeeeKLKERLEELEEDLSSLEQEIENVKSElkele 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1193 -KITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFE--KDEAIQTALDEfKLERELVEKELLEK-VKHLENQI- 1267
Cdd:TIGR02169 765 aRIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsRIEARLREIEQ-KLNRLTLEKEYLEKeIQELQEQRi 843
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1268 ---AKSPAFESAREDSSSLVAELQEKLqEEKAKFLEQLEEQEKRKNEEMQNVRTSLiAEQQTNFNTvLTREKMRKENIIN 1344
Cdd:TIGR02169 844 dlkEQIKSIEKEIENLNGKKEELEEEL-EELEAALRDLESRLGDLKKERDELEAQL-RELERKIEE-LEAQIEKKRKRLS 920
|
730 740
....*....|....*....|....*.
gi 157824101 1345 DLSDKLKSTMQQQERDKDLIESLSED 1370
Cdd:TIGR02169 921 ELKAKLEALEEELSEIEDPKGEDEEI 946
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
827-1370 |
2.88e-05 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 49.06 E-value: 2.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 827 KEQCDLSNYLKCTavEIRNIIDKVKcsleitlkeKHQQELQSLKIE-YECKLNTLEKDSEENVNKILKLKEDLVSLEEAL 905
Cdd:PTZ00440 672 KNEYEKLEFMKSD--NIDNIIKNLK---------KELQNLLSLKENiIKKQLNNIEQDISNSLNQYTIKYNDLKSSIEEY 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 906 QNKDSEFAIIKHE----KDAIVCMQHEKDQKLLEMENIM-----HTQNSEIKELKQSREMV-LEDLKKLHDEKIESLRAE 975
Cdd:PTZ00440 741 KEEEEKLEVYKHQiinrKNEFILHLYENDKDLPDGKNTYeeflqYKDTILNKENKISNDINiLKENKKNNQDLLNSYNIL 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 976 FQCLEQNHLKELEDTLHIRHTEEfEKVITDHKVSLEKLKKENQQKIDQMLEShasaIQEKEQQLQELK-VKVSDLSDMRC 1054
Cdd:PTZ00440 821 IQKLEAHTEKNDEELKQLLQKFP-TEDENLNLKELEKEFNENNQIVDNIIKD----IENMNKNINIIKtLNIAINRSNSN 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1055 KLEVElALKEAETDEIKILleESRTQQKETLKSLLEQETENLRTEINKLNQKIhdNSESYQVGLSELRslMTIEKdqcis 1134
Cdd:PTZ00440 896 KQLVE-HLLNNKIDLKNKL--EQHMKIINTDNIIQKNEKLNLLNNLNKEKEKI--EKQLSDTKINNLK--MQIEK----- 963
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1135 eLISRHEEesniLKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQR 1214
Cdd:PTZ00440 964 -TLEYYDK----SKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILNKKIDDLIKKQHDDIIELIDKLIKEKGK 1038
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1215 lamNHEQDKEQLIQKLNFEKD--EAIQTALDEFKLERELVE---KELLEKVKHLENQIakspafesarEDSSSLVAELQE 1289
Cdd:PTZ00440 1039 ---EIEEKVDQYISLLEKMKTklSSFHFNIDIKKYKNPKIKeeiKLLEEKVEALLKKI----------DENKNKLIEIKN 1105
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1290 KLQEEKAKFLEQLEEQE-----KRKN-----EEMQNVRTSLIA--EQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQ 1357
Cdd:PTZ00440 1106 KSHEHVVNADKEKNKQTehynkKKKSlekiyKQMEKTLKELENmnLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKS 1185
|
570
....*....|...
gi 157824101 1358 ERDKDLIESLSED 1370
Cdd:PTZ00440 1186 KTIMEEIESYKKD 1198
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
954-1190 |
3.42e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 3.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 954 REMVLEDlKKLHDEkIESLRAEFQCLEQNH-----LKELEDTL-HIR-HTEEFEKVITDHKVsLEKLKKENQQKIDQ-ML 1025
Cdd:COG4913 214 REYMLEE-PDTFEA-ADALVEHFDDLERAHealedAREQIELLePIReLAERYAAARERLAE-LEYLRAALRLWFAQrRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1026 ESHASAIQEKEQQLQELKVKVSDLsdmrcklEVELALKEAETDEIKILLEESRTQQKETLksllEQETENLRTEINKLNQ 1105
Cdd:COG4913 291 ELLEAELEELRAELARLEAELERL-------EARLDALREELDELEAQIRGNGGDRLEQL----EREIERLERELEERER 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1106 KihdnSESYQVGLSELR-SLMTIEKDqcISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQtklnSELS 1184
Cdd:COG4913 360 R----RARLEALLAALGlPLPASAEE--FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE----AEIA 429
|
....*.
gi 157824101 1185 ALEKQK 1190
Cdd:COG4913 430 SLERRK 435
|
|
| MAP65_ASE1 |
pfam03999 |
Microtubule associated protein (MAP65/ASE1 family); |
925-1153 |
3.44e-05 |
|
Microtubule associated protein (MAP65/ASE1 family);
Pssm-ID: 427641 [Multi-domain] Cd Length: 477 Bit Score: 48.46 E-value: 3.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 925 MQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLED--------------LKKLHDEKiESLRAEFQCLEQNHLKELEDt 990
Cdd:pfam03999 102 LRKEKAPRLAEIKELLEQLQQLCEELGEEPLPLLIDplpsleelesfrkhLENLRNEK-ERRLEEVNELKKQIKLLMEE- 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 991 LHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDmrcKLEVELALKEAETDEI 1070
Cdd:pfam03999 180 LDLVPGTDFEEDLLCESEDNFCLSRENIDKLRKLIKQLEEQKAEREEKIDDLREKILELWN---RLQVPQEEQESFVREN 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1071 KILLEESRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAE 1150
Cdd:pfam03999 257 NSLSQDTIDALREELQRLEELKKKNIKKLIEDLRVEIEELWDKLFYSTEQRKRFIPFFEELYTEDLLELHELELKRLKEE 336
|
...
gi 157824101 1151 LDS 1153
Cdd:pfam03999 337 YES 339
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
928-1106 |
4.46e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.84 E-value: 4.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 928 EKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNhLKELEDTLhirhtEEFEKVITDHK 1007
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL-ERRIAALARRIRALEQE-LAALEAEL-----AELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1008 VSLEKLKKE---------------------NQQKIDQ---MLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALK 1063
Cdd:COG4942 97 AELEAQKEElaellralyrlgrqpplalllSPEDFLDavrRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 157824101 1064 EAETDEIKIL---LEESRTQQKETLKSlLEQETENLRTEINKLNQK 1106
Cdd:COG4942 177 EALLAELEEEraaLEALKAERQKLLAR-LEKELAELAAELAELQQE 221
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
855-1067 |
4.74e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.45 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 855 EITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAivcMQHEKDQKLL 934
Cdd:COG4942 35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA---QKEELAELLR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 935 EMEniMHTQNSEIKELKQS--------REMVLEDLKKLHDEKIESLRAEfqcleQNHLKELEDTLHiRHTEEFEKVITDH 1006
Cdd:COG4942 112 ALY--RLGRQPPLALLLSPedfldavrRLQYLKYLAPARREQAEELRAD-----LAELAALRAELE-AERAELEALLAEL 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 157824101 1007 KVSLEKLKKENQQKiDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAET 1067
Cdd:COG4942 184 EEERAALEALKAER-QKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
1008-1329 |
4.89e-05 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 47.93 E-value: 4.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1008 VSLEKLKKENQQKidqmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLeVELALKEAetdeIKILLEESRTQQKETLKS 1087
Cdd:PLN03229 411 VPVDPERKVNMKK----REAVKTPVRELEGEVEKLKEQILKAKESSSKP-SELALNEM----IEKLKKEIDLEYTEAVIA 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1088 L-LEQETENLRTEINKLN-----------QKIHDNSESYQVGLSE----------LRSLMTIEKDQCISELISRHE---- 1141
Cdd:PLN03229 482 MgLQERLENLREEFSKANsqdqlmhpvlmEKIEKLKDEFNKRLSRapnylslkykLDMLNEFSRAKALSEKKSKAEklka 561
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1142 ----------------EESNILKAELDSVTAlhHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALI 1205
Cdd:PLN03229 562 einkkfkevmdrpeikEKMEALKAEVASSGA--SSGDELDDDLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDTA 639
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1206 QnlEKDKQRLAMNHEQDKEQLIQKL-NFEKDEAIQTALDEFKLERELVEK----ELLEKVKHLENQIAKSPAfesAREDS 1280
Cdd:PLN03229 640 E--QTPPPNLQEKIESLNEEINKKIeRVIRSSDLKSKIELLKLEVAKASKtpdvTEKEKIEALEQQIKQKIA---EALNS 714
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 157824101 1281 SSLvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFN 1329
Cdd:PLN03229 715 SEL-KEKFEELEAELAAARETAAESNGSLKNDDDKEEDSKEDGSRVEVN 762
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
825-1097 |
5.63e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.79 E-value: 5.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 825 VQKEQCDLSNYLKCTAVEIRNIIDKVKCSLEITLKEKHQQELQSLKIEYECKLntlekdseenvnkilkLKEDLVSLEEA 904
Cdd:pfam05483 539 LEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKI----------------LENKCNNLKKQ 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 905 LQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKK-LHDEKIEslraefqclEQNH 983
Cdd:pfam05483 603 IENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKeIEDKKIS---------EEKL 673
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 984 LKELEDTlhirhteefeKVITDHKVSLEK-LKKENQQKIDQM---LESHA----SAIQEKEQQLQELKVKVSDLSDMRCK 1055
Cdd:pfam05483 674 LEEVEKA----------KAIADEAVKLQKeIDKRCQHKIAEMvalMEKHKhqydKIIEERDSELGLYKNKEQEQSSAKAA 743
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 157824101 1056 LEVELALKEAETDEIKILLEESRtQQKETLKSLLEQETENLR 1097
Cdd:pfam05483 744 LEIELSNIKAELLSLKKQLEIEK-EEKEKLKMEAKENTAILK 784
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
874-1356 |
6.71e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 47.73 E-value: 6.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 874 ECKLNTLEKDSEenvNKILKLKEDLVSLEEALQNKDSEFAIIKHEKDAIVCMQHEKDQKLLEMENIMHTQNSEIKELK-- 951
Cdd:TIGR00606 690 EAELQEFISDLQ---SKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKnd 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 952 -QSREMVLEDLKKlHDEKIESLRAEFQCLEQNHLkELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQQK------IDQM 1024
Cdd:TIGR00606 767 iEEQETLLGTIMP-EEESAKVCLTDVTIMERFQM-ELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqheldtVVSK 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1025 LESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAetdeikilleesrtqqketlkslLEQETENLRTEINKLN 1104
Cdd:TIGR00606 845 IELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQ-----------------------FEEQLVELSTEVQSLI 901
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1105 QKIHDNSEsyqvglSELRSLMTIEKDQC-ISELISRHEEESNILKAELDsvtalhhqafEIEKKLKEQIVELQTKLNSel 1183
Cdd:TIGR00606 902 REIKDAKE------QDSPLETFLEKDQQeKEELISSKETSNKKAQDKVN----------DIKEKVKNIHGYMKDIENK-- 963
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1184 saLEKQKDEKITQQEEKYKALIQNLEKDKQRlAMNHEQDKEQLIQKLNFEK--DEAIQTALDEFKLERELveKELLEKVK 1261
Cdd:TIGR00606 964 --IQDGKDDYLKQKETELNTVNAQLEECEKH-QEKINEDMRLMRQDIDTQKiqERWLQDNLTLRKRENEL--KEVEEELK 1038
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1262 HLENQIAKSPAFESAREDSsslvaELQEKLQ---EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMR 1338
Cdd:TIGR00606 1039 QHLKEMGQMQVLQMKQEHQ-----KLEENIDlikRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTT 1113
|
490
....*....|....*...
gi 157824101 1339 KEnIINDLsDKLKSTMQQ 1356
Cdd:TIGR00606 1114 EL-VNKDL-DIYYKTLDQ 1129
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
854-1316 |
8.72e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 47.24 E-value: 8.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 854 LEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEFAIIKHEkdaivcmQHEKDQKL 933
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE-------LLEALRAA 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 934 LEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEfqclEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKL 1013
Cdd:COG1196 396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE----EEEEEALEEAAEEEAELEEEEEALLELLAELLEE 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1014 KKENQQKIDQMLESHASAIQEKEQQLQELK--------VKVSDLSDMRCKL--------EVELALKEAETDEIKILLEES 1077
Cdd:COG1196 472 AALLEAALAELLEELAEAAARLLLLLEAEAdyegflegVKAALLLAGLRGLagavavliGVEAAYEAALEAALAAALQNI 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1078 RTQQKETLKSLLEQETENLRTEINKL-NQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILkAELDSVTA 1156
Cdd:COG1196 552 VVEDDEVAAAAIEYLKAAKAGRATFLpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL-LGRTLVAA 630
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1157 LHHQAFEIEKKLKEQ--IVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQliqklnfek 1234
Cdd:COG1196 631 RLEAALRRAVTLAGRlrEVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA--------- 701
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1235 dEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQ 1314
Cdd:COG1196 702 -EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
|
..
gi 157824101 1315 NV 1316
Cdd:COG1196 781 PV 782
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
843-1108 |
1.04e-04 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 46.93 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 843 IRNIIDKVKCSLEitlKEKHQQ------ELQSLKIEYECKLNTLEKDSEENVNKILK---------LKEDLVSLEEALQN 907
Cdd:NF033838 67 LEKILSEIQKSLD---KRKHTQnvalnkKLSDIKTEYLYELNVLKEKSEAELTSKTKkeldaafeqFKKDTLEPGKKVAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 908 KDSEFAIIKHEKDAivcmQHEKDQ--------KLLEMEnimhTQNSEIKELKQSREMVLEDLKKLHDE--------KIES 971
Cdd:NF033838 144 ATKKVEEAEKKAKD----QKEEDRrnyptntyKTLELE----IAESDVEVKKAELELVKEEAKEPRDEekikqakaKVES 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 972 LRAEFQCLE--QNHLKELEDTLHIRHTEEFEKVITDHKVSLEKL------------------KKENQQKI------DQML 1025
Cdd:NF033838 216 KKAEATRLEkiKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDkpkrrakrgvlgepatpdKKENDAKSsdssvgEETL 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1026 ESHA----SAIQEKEQQLQELKVKVSDL--SDMRC-------KLEVELA-----LKEAETDEIKILLEESRT-----QQK 1082
Cdd:NF033838 296 PSPSlkpeKKVAEAEKKVEEAKKKAKDQkeEDRRNyptntykTLELEIAesdvkVKEAELELVKEEAKEPRNeekikQAK 375
|
330 340
....*....|....*....|....*...
gi 157824101 1083 ETLKSLLEQET--ENLRTEINKLNQKIH 1108
Cdd:NF033838 376 AKVESKKAEATrlEKIKTDRKKAEEEAK 403
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
773-1104 |
1.08e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 773 SRRMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHISIQTIKDDLCHFRTFVQKEQCDLSnYLKCTAVEIRNIIDKVKC 852
Cdd:TIGR02169 708 SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIE-ELEEDLHKLEEALNDLEA 786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 853 SLEITLKEKHQQELQSLKiEYECKLNTLEKDSEENVNKILKLKEdlvSLEEALQNKDSEFAIIKHEKDAIVCMQH----- 927
Cdd:TIGR02169 787 RLSHSRIPEIQAELSKLE-EEVSRIEARLREIEQKLNRLTLEKE---YLEKEIQELQEQRIDLKEQIKSIEKEIEnlngk 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 928 --EKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQnHLKELEDTLHIRHTEEFE----- 1000
Cdd:TIGR02169 863 keELEEELEELEAALRDLESRLGDLKKERDELEAQLREL-ERKIEELEAQIEKKRK-RLSELKAKLEALEEELSEiedpk 940
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1001 ---KVITDHKVSLEKLKKENQ---QKIDQMLESHASAIQEKEQQLQELKvkvsDLSDMRCKLevelalkEAETDEIKILL 1074
Cdd:TIGR02169 941 gedEEIPEEELSLEDVQAELQrveEEIRALEPVNMLAIQEYEEVLKRLD----ELKEKRAKL-------EEERKAILERI 1009
|
330 340 350
....*....|....*....|....*....|
gi 157824101 1075 EESRTQQKETLKSLLEQETENLRTEINKLN 1104
Cdd:TIGR02169 1010 EEYEKKKREVFMEAFEAINENFNEIFAELS 1039
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
845-1342 |
1.38e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.97 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 845 NIIDK-VKCSLEITLKEKhQQELQslKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEAL------QNKDSEFAIIKH 917
Cdd:TIGR01612 958 NLIEKsYKDKFDNTLIDK-INELD--KAFKDASLNDYEAKNNELIKYFNDLKANLGKNKENMlyhqfdEKEKATNDIEQK 1034
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 918 EKDAivcmqhekDQKLLEMENIMHTqnseikelkqSREMVLEDLKKLHDEKIESL------RAEFQCLEQNHLKE----- 986
Cdd:TIGR01612 1035 IEDA--------NKNIPNIEIAIHT----------SIYNIIDEIEKEIGKNIELLnkeileEAEINITNFNEIKEklkhy 1096
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 987 -LEDTL---HIRHTEEFEKVitdhkvsleklkKENQQKIDQMLESHASAIQE----KEQQLQELKVKVSDLSDMrckleV 1058
Cdd:TIGR01612 1097 nFDDFGkeeNIKYADEINKI------------KDDIKNLDQKIDHHIKALEEikkkSENYIDEIKAQINDLEDV-----A 1159
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1059 ELALKEAETDEIKILLEESRTqqKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQcISELIS 1138
Cdd:TIGR01612 1160 DKAISNDDPEEIEKKIENIVT--KIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEK-IDEEKK 1236
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1139 RHEEESNILKAELDSVTALHHQAFEIEKKLKeqiveLQTKLNSELSAL-------------EKQKDEKITQQEEKYKALI 1205
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDLDEIKEKSPEIENEMG-----IEMDIKAEMETFnishdddkdhhiiSKKHDENISDIREKSLKII 1311
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1206 QNLEKDKQRLAMNHEQDKEQL-IQKLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAK-SPAFESAREDSSSL 1283
Cdd:TIGR01612 1312 EDFSEESDINDIKKELQKNLLdAQKHNSDINLYLNEIANIYNILKLNKIKKIIDEVKEYTKEIEEnNKNIKDELDKSEKL 1391
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157824101 1284 VAELQE--KLQEEKAKFLEQLEeqEKRKNEEMQNVRTS--LIAEQQTNFNTVLTREKMRKENI 1342
Cdd:TIGR01612 1392 IKKIKDdiNLEECKSKIESTLD--DKDIDECIKKIKELknHILSEESNIDTYFKNADENNENV 1452
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
997-1328 |
1.53e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 46.29 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 997 EEFEKVITDHKVSL-EKLKKENQQKIDQMLESHAS---AIQEKEQQLQELKVKVSDLSDmrcklEVELALKEAETDEIKI 1072
Cdd:pfam09731 84 EEKKQVKIPRQSGVsSEVAEEEKEATKDAAEAKAQlpkSEQEKEKALEEVLKEAISKAE-----SATAVAKEAKDDAIQA 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1073 LLEE-------------SRTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISR 1139
Cdd:pfam09731 159 VKAHtdslkeasdtaeiSREKATDSALQKAEALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKA 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1140 HEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELqtklnSELSALEKqkdekitqqeEKYKALIQNLEKDKQRLamnh 1219
Cdd:pfam09731 239 QSLAKLVDQYKELVASERIVFQQELVSIFPDIIPVL-----KEDNLLSN----------DDLNSLIAHAHREIDQL---- 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1220 eqdkEQLIQKLNFEKDEAIQTALDEFKLERELVEKELLEKVK-HLENQIAKSPA-FESAREDS-----SSLVAELQEKLQ 1292
Cdd:pfam09731 300 ----SKKLAELKKREEKHIERALEKQKEELDKLAEELSARLEeVRAADEAQLRLeFEREREEIresyeEKLRTELERQAE 375
|
330 340 350
....*....|....*....|....*....|....*.
gi 157824101 1293 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNF 1328
Cdd:pfam09731 376 AHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGR 411
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1141-1278 |
1.58e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.31 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1141 EEESNILK--AELDSVTALHHQAFEIEKKLKEQIVELQTK----------LNSELSALEKqKDEKITQQEEKYKALIQNL 1208
Cdd:PRK12704 48 KKEAEAIKkeALLEAKEEIHKLRNEFEKELRERRNELQKLekrllqkeenLDRKLELLEK-REEELEKKEKELEQKQQEL 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1209 EKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDefKLERELvEKELLEKVKHLENQiAKSPAFESARE 1278
Cdd:PRK12704 127 EKKEEELEELIEEQLQELERISGLTAEEAKEILLE--KVEEEA-RHEAAVLIKEIEEE-AKEEADKKAKE 192
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1174-1389 |
2.06e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.53 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1174 ELQTKLNSELSALEKQKDE---KITQQEEKYKALIQNLEKDKQRLAmnheqDKEQLIQKLNfEKDEAIQTALDEFKLERE 1250
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAElekELAALKKEEKALLKQLAALERRIA-----ALARRIRALE-QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1251 LVEKELLEKVKHLENQIAKspAFESAREDSSSLVAELQEKLQEEK-AKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTnfn 1329
Cdd:COG4942 94 ELRAELEAQKEELAELLRA--LYRLGRQPPLALLLSPEDFLDAVRrLQYLKYLAPARREQAEELRADLAELAALRAE--- 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1330 tvLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEekkkleeEVSKLR 1389
Cdd:COG4942 169 --LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAA-------ELAELQ 219
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
945-1109 |
2.29e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.54 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 945 SEIKELKQSREMVLEDLKK----LHDEKIESLRAEFQCLEQNHLKELEDTLhiRHTEEFEKVITDHKVSLEKlKKENQQK 1020
Cdd:PRK12704 31 AKIKEAEEEAKRILEEAKKeaeaIKKEALLEAKEEIHKLRNEFEKELRERR--NELQKLEKRLLQKEENLDR-KLELLEK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1021 IDQMLESHASAIQEKEQQLQELKVKvsdlsdmrcklevelaLKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTEI 1100
Cdd:PRK12704 108 REEELEKKEKELEQKQQELEKKEEE----------------LEELIEEQLQELERISGLTAEEAKEILLEKVEEEARHEA 171
|
....*....
gi 157824101 1101 NKLNQKIHD 1109
Cdd:PRK12704 172 AVLIKEIEE 180
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1019-1175 |
2.87e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 2.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1019 QKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKE--TLKSL--LEQETE 1094
Cdd:COG1579 20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYeaLQKEIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1095 NLRTEINKLNQKI---HDNSESYQVGLSELRSLMTIEKDQcISELISRHEEESNILKAELDSVTAlhhQAFEIEKKLKEQ 1171
Cdd:COG1579 100 SLKRRISDLEDEIlelMERIEELEEELAELEAELAELEAE-LEEKKAELDEELAELEAELEELEA---EREELAAKIPPE 175
|
....
gi 157824101 1172 IVEL 1175
Cdd:COG1579 176 LLAL 179
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
936-1084 |
3.10e-04 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 44.62 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 936 MENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIEsLRAEFQCL--EQNHLKELEDTLHIRHTEEFEKVitdhKVSLEKL 1013
Cdd:smart00787 142 LEGLKEGLDENLEGLKEDYKLLMKELELLNSIKPK-LRDRKDALeeELRQLKQLEDELEDCDPTELDRA----KEKLKKL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1014 KKENQQKIDQmleshasaIQEKEQQLQELKVKVSDLSDMrcKLEVELALKEAET----------DEIKILLEESRTQQKE 1083
Cdd:smart00787 217 LQEIMIKVKK--------LEELEEELQELESKIEDLTNK--KSELNTEIAEAEKkleqcrgftfKEIEKLKEQLKLLQSL 286
|
.
gi 157824101 1084 T 1084
Cdd:smart00787 287 T 287
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1161-1318 |
3.27e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 45.59 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1161 AFEIEKKL----------KEQIVELQTKLN---SELSALEKQKDEKITQQEEkykaLIQNLEKDKQRLamnheqdkEQLI 1227
Cdd:PRK00409 490 AFEIAKRLglpeniieeaKKLIGEDKEKLNeliASLEELERELEQKAEEAEA----LLKEAEKLKEEL--------EEKK 557
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1228 QKLNFEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREdssslvaelqekLQEEKAKFLEQLEEQEK 1307
Cdd:PRK00409 558 EKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYASVKAHE------------LIEARKRLNKANEKKEK 625
|
170
....*....|.
gi 157824101 1308 RKNEEMQNVRT 1318
Cdd:PRK00409 626 KKKKQKEKQEE 636
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1015-1311 |
3.38e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.89 E-value: 3.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1015 KENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSL--LEQE 1092
Cdd:COG4372 9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELeeLNEQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1093 TENLRTEINKLNQKIHDNSESYQVGLSELRSLmtiekdqciselisrhEEESNILKAELDSVTALHHQAFEIEKKLKEQI 1172
Cdd:COG4372 89 LQAAQAELAQAQEELESLQEEAEELQEELEEL----------------QKERQDLEQQRKQLEAQIAELQSEIAEREEEL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1173 VELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELV 1252
Cdd:COG4372 153 KELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLG 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 157824101 1253 EKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNE 1311
Cdd:COG4372 233 LALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEA 291
|
|
| Caldesmon |
pfam02029 |
Caldesmon; |
948-1113 |
3.46e-04 |
|
Caldesmon;
Pssm-ID: 460421 [Multi-domain] Cd Length: 495 Bit Score: 45.24 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 948 KELKQSREM-VLEDLKKLHDE-KIESLRAEFQCLEQNHLKELEDTLHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQML 1025
Cdd:pfam02029 186 KEKKVKYESkVFLDQKRGHPEvKSQNGEEEVTKLKVTTKRRQGGLSQSQEREEEAEVFLEAEQKLEELRRRRQEKESEEF 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1026 ESHASAIQEKEQQLQELKVKvsdLSDMRCKLEVELALKEAETDEIKILLEESRTQQKEtlkslleqETENLRTEINKLNQ 1105
Cdd:pfam02029 266 EKLRQKQQEAELELEELKKK---REERRKLLEEEEQRRKQEEAERKLREEEEKRRMKE--------EIERRRAEAAEKRQ 334
|
....*...
gi 157824101 1106 KIHDNSES 1113
Cdd:pfam02029 335 KLPEDSSS 342
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
902-1472 |
3.60e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.55 E-value: 3.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 902 EEALQNKDSEFAIIKHEKDAIVCMQHEKDQKllemenimHTQNSEIKELKQSRemvLEDLKKLHDEKiESLRAEFQCLEQ 981
Cdd:pfam01576 4 EEEMQAKEEELQKVKERQQKAESELKELEKK--------HQQLCEEKNALQEQ---LQAETELCAEA-EEMRARLAARKQ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 982 nhlkELEDTLH---IRHTEEFEKVitdhkVSLEKLKKENQQKIdQMLESHASAIQEKEQQLQELKVKVsdlsdmrcklev 1058
Cdd:pfam01576 72 ----ELEEILHeleSRLEEEEERS-----QQLQNEKKKMQQHI-QDLEEQLDEEEAARQKLQLEKVTT------------ 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1059 ELALKEAEtDEIKILLEESRTQQKEtlKSLLEQETENLRTEINKLNQKihdnSESYQVGLSELRSLMTIEKDQCISELIS 1138
Cdd:pfam01576 130 EAKIKKLE-EDILLLEDQNSKLSKE--RKLLEERISEFTSNLAEEEEK----AKSLSKLKNKHEAMISDLEERLKKEEKG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1139 RHEEESNILKAELDSVTalhhqafeiekkLKEQIVELQTKLnSELSAlekqkdeKITQQEEKYKALIQNLEKDKqrLAMN 1218
Cdd:pfam01576 203 RQELEKAKRKLEGESTD------------LQEQIAELQAQI-AELRA-------QLAKKEEELQAALARLEEET--AQKN 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1219 HEQDKEQLIQKLNFEkdeaIQTALDEFKLERELVEK------ELLEKVK-HLENQIAKSPAFESAREDSSSLVAELQEKL 1291
Cdd:pfam01576 261 NALKKIRELEAQISE----LQEDLESERAARNKAEKqrrdlgEELEALKtELEDTLDTTAAQQELRSKREQEVTELKKAL 336
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1292 QEEKAKFLEQLEEQEKRKNEEMQNVRTSLiaEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQ----QQERDKDLIESL 1367
Cdd:pfam01576 337 EEETRSHEAQLQEMRQKHTQALEELTEQL--EQAKRNKANLEKAKQALESENAELQAELRTLQQakqdSEHKRKKLEGQL 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1368 SEDRARLLEEKKKLEEEVSKLRTSSVlpsapvlaapELYGACApeLPGEPERSAMETTDEGrvdSAMETSMMSVQENMLS 1447
Cdd:pfam01576 415 QELQARLSESERQRAELAEKLSKLQS----------ELESVSS--LLNEAEGKNIKLSKDV---SSLESQLQDTQELLQE 479
|
570 580
....*....|....*....|....*
gi 157824101 1448 EEKQRIMLLERTLQLKEEENKRLNQ 1472
Cdd:pfam01576 480 ETRQKLNLSTRLRQLEDERNSLQEQ 504
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
1186-1351 |
3.66e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.15 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1186 LEKQKDEKITQQEEKYKALIQNLEKDKQRLamnheqdkeqliqklnfeKDEAIQTALDEFKLERELVEKELLEK---VKH 1262
Cdd:PRK12704 25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAI------------------KKEALLEAKEEIHKLRNEFEKELRERrneLQK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1263 LENQIAKSpafESAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNvrtsLIAEQQTNFNTV--LTREKMRKE 1340
Cdd:PRK12704 87 LEKRLLQK---EENLDRKLELLEKREEELEKKEKE-LEQKQQELEKKEEELEE----LIEEQLQELERIsgLTAEEAKEI 158
|
170
....*....|.
gi 157824101 1341 nIINDLSDKLK 1351
Cdd:PRK12704 159 -LLEKVEEEAR 168
|
|
| ATG17_like |
pfam04108 |
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ... |
312-537 |
4.57e-04 |
|
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.
Pssm-ID: 427715 [Multi-domain] Cd Length: 360 Bit Score: 44.30 E-value: 4.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 312 NVQDRPNDVESLVRKCFDSMSRLDPKIIQPFMLECHQTIAKLDNQNMKAikgLEDRLYALDQMIASCSRLVNEQKELAQG 391
Cdd:pfam04108 127 ELQAAQESLDSDLKRFDDDLRDLQKELESLSSPSESISLIPTLLKELES---LEEEMASLLESLTNHYDQCVTAVKLTEG 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 392 FLANqMRAENLKDASVLPDLCLSHANQLMIMLQNHRKLLDIKQKCTTAKQELANNLHV------RLKWCCFVMLHADQDG 465
Cdd:pfam04108 204 GRAE-MLEVLENDARELDDVVPELQDRLDEMENNYERLQKLLEQKNSLIDELLSALQLiaeiqsRLPEYLAALKEFEERW 282
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157824101 466 EKLQALLRLVIELLERVRivEALSTVPQMYCLAVVEVVRRKMFIKHYREWAGALVKDGKQLYEAEKSKRESF 537
Cdd:pfam04108 283 EEEKETIEDYLSELEDLR--EFYEGFPSAYGSLLLEVERRREWAEKMKKILRKLAEELDRLQEEERKRREKF 352
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
983-1344 |
6.00e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 6.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 983 HLKELEDTLHIRHTEEFEKVITDHKVSLE---KLKKENQQKIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVE 1059
Cdd:TIGR01612 501 RMKDFKDIIDFMELYKPDEVPSKNIIGFDidqNIKAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKE 580
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1060 ---LALKEAETDEIKILLEESRTQQKETLKSLLEQeTENLRTEINKlnQKIHDNSESYQVGLSELRSLMTIE----KDQC 1132
Cdd:TIGR01612 581 ikdLFDKYLEIDDEIIYINKLKLELKEKIKNISDK-NEYIKKAIDL--KKIIENNNAYIDELAKISPYQVPEhlknKDKI 657
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1133 ISELISrheEESNILKAELDsvtALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDK 1212
Cdd:TIGR01612 658 YSTIKS---ELSKIYEDDID---ALYNELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKK 731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1213 QRLAMNHEQDKEQLIQKLNFEkdeaIQTALDEFKlerelvekellEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQ 1292
Cdd:TIGR01612 732 NELLDIIVEIKKHIHGEINKD----LNKILEDFK-----------NKEKELSNKINDYAKEKDELNKYKSKISEIKNHYN 796
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 157824101 1293 EEKAkfLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIIN 1344
Cdd:TIGR01612 797 DQIN--IDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLN 846
|
|
| Ubl_TBK1_like |
cd12219 |
ubiquitin-like (Ubl) domain found in non-canonical Inhibitor of kappa B kinases IKKepsilon and ... |
3-76 |
8.03e-04 |
|
ubiquitin-like (Ubl) domain found in non-canonical Inhibitor of kappa B kinases IKKepsilon and TBK1, and similar proteins; IKKepsilon and TBK1 (TRAF family member-associated NF-kappaB activator-binding kinase 1) are non-canonical members of IKK family. They have been characterized as activators of nuclear factor-kappaB (NF-kappaB), but they are not essential for NF-kappaB activation. They play critical roles in antiviral response via phosphorylation and activation of transcription factors IRF3, IRF7, STAT1 and STAT3. They are also involved in the survival, tumorigenesis and development of various cancers. Both IKKepsilon and TBK1 contain an N-terminal protein kinase domain followed a ubiquitin-like (Ubl) domain. The Ubl domain acts as a protein-protein interaction domain, and has been implicated in regulating kinase activity, which modulates interactions in the interferon pathway.
Pssm-ID: 340518 Cd Length: 77 Bit Score: 39.52 E-value: 8.03e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 3 LYVFLVNTGTTLTF---DTEltvqTVADLKHAIQSKYKIAVQHQVLVVNGGE-CMTADRRVCTYSAGTDTNPIFLFNK 76
Cdd:cd12219 4 IHVFSVSTCELLKIyldPTE----TLAEFQELIAEQTEIPAKNQLLLFEGQLlEEEVTLPVSDYPKTTEENPIILFNK 77
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1128-1359 |
8.17e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 8.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1128 EKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQtKLNSELSALEKQkdekITQQEEKYKALIQN 1207
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAE----LAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1208 LEKDKQRLA-------MNHEQDKEQLIqkLNFEkdeaiqtalDEFKLERELvekELLEKV-KHLENQIAkspAFESARED 1279
Cdd:COG4942 99 LEAQKEELAellralyRLGRQPPLALL--LSPE---------DFLDAVRRL---QYLKYLaPARREQAE---ELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1280 SSSLVAELQEKlQEEKAKFLEQLEEQEKRKNEEMQNvRTSLIAEQQTNFNTVLTR--EKMRKENIINDLSDKLKSTMQQQ 1357
Cdd:COG4942 162 LAALRAELEAE-RAELEALLAELEEERAALEALKAE-RQKLLARLEKELAELAAElaELQQEAEELEALIARLEAEAAAA 239
|
..
gi 157824101 1358 ER 1359
Cdd:COG4942 240 AE 241
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1038-1467 |
8.69e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 43.96 E-value: 8.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1038 QLQELKVKVSDLSDmrcklevELALKEAETDEIKILLEESRTQQKETLKSLLEQETEnLRTEINKLNQKIHDNSESYQVG 1117
Cdd:pfam05557 3 ELIESKARLSQLQN-------EKKQMELEHKRARIELEKKASALKRQLDRESDRNQE-LQKRIRLLEKREAEAEEALREQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1118 LSELRSLMTIEkdqcisELISRHEEESNILKAEL-DSVTALHHQAFEIEKKLKEQIVELQTKlNSELSALEKQKDEKITQ 1196
Cdd:pfam05557 75 AELNRLKKKYL------EALNKKLNEKESQLADArEVISCLKNELSELRRQIQRAELELQST-NSELEELQERLDLLKAK 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1197 QEEkYKALIQNLEKDKQRLAMNHEQDKEqLIQKLNFEKDEAIQTALDEFKLER----ELVEKELLEKVKHLENQI----- 1267
Cdd:pfam05557 148 ASE-AEQLRQNLEKQQSSLAEAEQRIKE-LEFEIQSQEQDSEIVKNSKSELARipelEKELERLREHNKHLNENIenkll 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1268 ---------AKSPAFESAREDSSSLVAELQEKLQEEKA-KFLEQLEEQEKRKNEEmqnVRTSLIAEQQTNF-----NTVL 1332
Cdd:pfam05557 226 lkeevedlkRKLEREEKYREEAATLELEKEKLEQELQSwVKLAQDTGLNLRSPED---LSRRIEQLQQREIvlkeeNSSL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1333 TREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRtsSVLPSAPVLAAPELYGacaPE 1412
Cdd:pfam05557 303 TSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYR--AILESYDKELTMSNYS---PQ 377
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 157824101 1413 LPgEPERSAMETTDEGRVDSAMETSMMSVQENMLSEEKQRIMLLERTLQLKEEEN 1467
Cdd:pfam05557 378 LL-ERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQE 431
|
|
| OmpH |
smart00935 |
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ... |
1178-1269 |
1.51e-03 |
|
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.
Pssm-ID: 214922 [Multi-domain] Cd Length: 140 Bit Score: 40.64 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1178 KLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELL 1257
Cdd:smart00935 18 AAQKQLEKEFKKRQAELEKLEKELQKLKEKLQKDAATLSEAAREKKEKELQKKVQEFQRKQQKLQQDLQKRQQEELQKIL 97
|
90
....*....|..
gi 157824101 1258 EKVKHLENQIAK 1269
Cdd:smart00935 98 DKINKAIKEVAK 109
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
957-1192 |
1.59e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 43.08 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 957 VLEDLKKLHDEKIESLRAEFQCLEqnhlkeledtLHIRHTEEFEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQEKE 1036
Cdd:PHA02562 164 VLSEMDKLNKDKIRELNQQIQTLD----------MKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1037 QQLQELKVKVS-------DLSDMRCKLEVELALKEAETDEIK------------------ILLEESRTQQKETLKSLLEQ 1091
Cdd:PHA02562 234 AEIEELTDELLnlvmdieDPSAALNKLNTAAAKIKSKIEQFQkvikmyekggvcptctqqISEGPDRITKIKDKLKELQH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1092 ETENLRTEINKLNQKIHDNSESyQVGLSELRSLMTIEKDQciselISRHEEESNILKAELDSVTAlhhqAFEIEKKLKEQ 1171
Cdd:PHA02562 314 SLEKLDTAIDELEEIMDEFNEQ-SKKLLELKNKISTNKQS-----LITLVDKAKKVKAAIEELQA----EFVDNAEELAK 383
|
250 260
....*....|....*....|.
gi 157824101 1172 IVELQTKLNSELSALEKQKDE 1192
Cdd:PHA02562 384 LQDELDKIVKTKSELVKEKYH 404
|
|
| FAM184 |
pfam15665 |
Family with sequence similarity 184, A and B; The function of FAM184 is not known. |
857-1046 |
1.70e-03 |
|
Family with sequence similarity 184, A and B; The function of FAM184 is not known.
Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 41.57 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 857 TLKEKHQQELQSLKIEYECKLNTLEKDSEENvnkiLKLKEDLVSLEEALQnkdsefaiikhekdaivcmQHEKDQKLLEM 936
Cdd:pfam15665 18 ALKEAHEEEIQQILAETREKILQYKSKIGEE----LDLKRRIQTLEESLE-------------------QHERMKRQALT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 937 ENIMHTQNSEIKELKQ-----------SREMvlEDLKKLHDEKIESLRAEFQCLEQNHLKELEDtLHIRHTEEFEKVITD 1005
Cdd:pfam15665 75 EFEQYKRRVEERELKAeaehrqrvvelSREV--EEAKRAFEEKLESFEQLQAQFEQEKRKALEE-LRAKHRQEIQELLTT 151
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 157824101 1006 HKVSLEKLKKEnQQKIDQMLESHASAIQEKEQQLQELKVKV 1046
Cdd:pfam15665 152 QRAQSASSLAE-QEKLEELHKAELESLRKEVEDLRKEKKKL 191
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
951-1106 |
2.02e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.89 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 951 KQSREMVLEDLKKLhDEKIESLraefqcleQNHLKELEDtlHIRHTEEFEKvitdhkvSLEKLKKENQQKIDQMLESHAS 1030
Cdd:PRK00409 505 EEAKKLIGEDKEKL-NELIASL--------EELERELEQ--KAEEAEALLK-------EAEKLKEELEEKKEKLQEEEDK 566
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 157824101 1031 AIQEKEQQLQElkvkvsdlsdmrcklevelALKEAeTDEIKILLEESRTQQKETLKSLLEQETENLRTEINKLNQK 1106
Cdd:PRK00409 567 LLEEAEKEAQQ-------------------AIKEA-KKEADEIIKELRQLQKGGYASVKAHELIEARKRLNKANEK 622
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
775-1369 |
2.08e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.12 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 775 RMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHI--------SIQTIKDDLCHFRTFVQKEQCDLSNyLKCTAVEIRNI 846
Cdd:TIGR01612 1611 KISDIKKKINDCLKETESIEKKISSFSIDSQDTELkengdnlnSLQEFLESLKDQKKNIEDKKKELDE-LDSEIEKIEID 1689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 847 IDKVKCSLEITLKEKHQQELQSLKIEYEcKLNTLEKDSEENVNKILKLKE-DLVSLEEALQNKDSEFAIIKHEKDAIVCM 925
Cdd:TIGR01612 1690 VDQHKKNYEIGIIEKIKEIAIANKEEIE-SIKELIEPTIENLISSFNTNDlEGIDPNEKLEEYNTEIGDIYEEFIELYNI 1768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 926 QhEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRA-EFQCLeQNHLKELEDTLHIRHTEEFEKV-- 1002
Cdd:TIGR01612 1769 I-AGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKKSKSYLDDIEAkEFDRI-INHFKKKLDHVNDKFTKEYSKIne 1846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1003 -ITDHKVSLEKLKKENQQK-----IDQMLESHASAIQEKEQQLQELKVKV-SDLSDMRCKLEVELALKEAET--DEIKI- 1072
Cdd:TIGR01612 1847 gFDDISKSIENVKNSTDENllfdiLNKTKDAYAGIIGKKYYSYKDEAEKIfINISKLANSINIQIQNNSGIDlfDNINIa 1926
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1073 LLEESRTQQKETLKSLLEQETE-NLRTEI-NKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNIL--- 1147
Cdd:TIGR01612 1927 ILSSLDSEKEDTLKFIPSPEKEpEIYTKIrDSYDTLLDIFKKSQDLHKKEQDTLNIIFENQQLYEKIQASNELKDTLsdl 2006
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1148 --KAE--LDSVTALHHQAFEIEK-----KLKEQIVEL--QTKLNSELSALEKQK-----DEKITQQEEKYKALIQNLEKD 1211
Cdd:TIGR01612 2007 kyKKEkiLNDVKLLLHKFDELNKlscdsQNYDTILELskQDKIKEKIDNYEKEKekfgiDFDVKAMEEKFDNDIKDIEKF 2086
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1212 KqrlamNHEQDKEQLIQKLNFEKDEAIQT--ALDE----FKLERELVEKELLEKvKHLENQIAKSPAfESAREDSSSLVA 1285
Cdd:TIGR01612 2087 E-----NNYKHSEKDNHDFSEEKDNIIQSkkKLKElteaFNTEIKIIEDKIIEK-NDLIDKLIEMRK-ECLLFSYATLVE 2159
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1286 ELQEKLQEEkAKFLEQLEEQEKRKNEEMQNVRTSL---IAEQQTNFNTVLTREKMrkENIINDLSDKLKSTMQQQERDKD 1362
Cdd:TIGR01612 2160 TLKSKVINH-SEFITSAAKFSKDFFEFIEDISDSLnddIDALQIKYNLNQTKKHM--ISILADATKDHNNLIEKEKEATK 2236
|
....*..
gi 157824101 1363 LIESLSE 1369
Cdd:TIGR01612 2237 IINNLTE 2243
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
870-1307 |
2.18e-03 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 42.73 E-value: 2.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 870 KIEYECKLN--TLEKDSEENVNKILKLKEDL------VSLEEALQNKDS-EFAIIKH-----------EKDAIVcMQHEK 929
Cdd:PTZ00108 928 TVHFTVKLNdgVLEQWEEEGIEKVFKLKSTIsttnmvLFDENGKIKKYSdALDILKEfylvrldlykkRKEYLL-GKLER 1006
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 930 DQKLLE--MENIMHTQNSEIKELKQSREMVLEDLKKL--------HDEKIESLRA--EFQCLEQNHLKELEDTLHIRHTE 997
Cdd:PTZ00108 1007 ELARLSnkVRFIKHVINGELVITNAKKKDLVKELKKLgyvrfkdiIKKKSEKITAeeEEGAEEDDEADDEDDEEELGAAV 1086
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 998 EFEKVItdhKVSLEKLKKEnqqKIDQMLESHAsaiqEKEQQLQELKVK------VSDLSdmrcklEVELALKEAETDEIK 1071
Cdd:PTZ00108 1087 SYDYLL---SMPIWSLTKE---KVEKLNAELE----KKEKELEKLKNTtpkdmwLEDLD------KFEEALEEQEEVEEK 1150
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1072 ILLEESRTQQKETLKSLLEQETEnLRTEINKLNQKIHDNSesyqvglselRSLMTIEKDQCISELISRHEEESNILKAEL 1151
Cdd:PTZ00108 1151 EIAKEQRLKSKTKGKASKLRKPK-LKKKEKKKKKSSADKS----------KKASVVGNSKRVDSDEKRKLDDKPDNKKSN 1219
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1152 DSVTALHHQAFEIEKKLKEQIVELQTKLN--SELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEqliqk 1229
Cdd:PTZ00108 1220 SSGSDQEDDEEQKTKPKKSSVKRLKSKKNnsSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDG----- 1294
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157824101 1230 lnfEKDEAIQTALDEFKLERELVEKELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQEK 1307
Cdd:PTZ00108 1295 ---ESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDD 1369
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
958-1259 |
2.26e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 42.52 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 958 LEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHT-EEFEKVITDHKVS-------LEKLKKENQQKIDQMLE--- 1026
Cdd:PRK04778 110 IESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLyRELRKSLLANRFSfgpaldeLEKQLENLEEEFSQFVElte 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1027 --SHASA---IQEKEQQLQELKVKVSDLSDMRCKLEVEL--ALKEAET------------DEIKIL--LEESRTQQKETL 1085
Cdd:PRK04778 190 sgDYVEAreiLDQLEEELAALEQIMEEIPELLKELQTELpdQLQELKAgyrelveegyhlDHLDIEkeIQDLKEQIDENL 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1086 KSLLEQETENLRTEINKLNQKIhdnSESYQVGLSELRSLMTIEKDQ-CISELISRHEEESNILKAELDSVTalhhQAFEi 1164
Cdd:PRK04778 270 ALLEELDLDEAEEKNEEIQERI---DQLYDILEREVKARKYVEKNSdTLPDFLEHAKEQNKELKEEIDRVK----QSYT- 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1165 ekkLKEQIVELQTKLNSELSALEKQKD---EKITQQEEKYKALIQNLEKDKQRLAM---NHEQDKEQLIQklnFEKDEAI 1238
Cdd:PRK04778 342 ---LNESELESVRQLEKQLESLEKQYDeitERIAEQEIAYSELQEELEEILKQLEEiekEQEKLSEMLQG---LRKDELE 415
|
330 340
....*....|....*....|..
gi 157824101 1239 -QTALDEFKLERELVeKELLEK 1259
Cdd:PRK04778 416 aREKLERYRNKLHEI-KRYLEK 436
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
919-1307 |
2.38e-03 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 42.36 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 919 KDAIVCMQHEKDQKLL-EMENIMHTQNSEIKELKQSREMVLeDLKK---LHDEKIESLRAEfqcLEQNHLKELEDTlhir 994
Cdd:pfam15742 4 GEKLKYQQQEEVQQLRqNLQRLQILCTSAEKELRYERGKNL-DLKQhnsLLQEENIKIKAE---LKQAQQKLLDST---- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 995 hteefeKVITDHKVSLEKLkkenQQKIDQM-LESHASAIQEKEQ-----QLQELKVKVSDLSDMRckLEVELALKEAEtd 1068
Cdd:pfam15742 76 ------KMCSSLTAEWKHC----QQKIRELeLEVLKQAQSIKSQnslqeKLAQEKSRVADAEEKI--LELQQKLEHAH-- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1069 eiKILLEESRTQQKETLKSLLEQETEN---LRTEINKLNQK---IHDNSESYQVGLSELRslmtiEKDQCISELISRHEE 1142
Cdd:pfam15742 142 --KVCLTDTCILEKKQLEERIKEASENeakLKQQYQEEQQKrklLDQNVNELQQQVRSLQ-----DKEAQLEMTNSQQQL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1143 ESNILKAELdsvtalhhQAFEIEKKLKEQIVELQTKLNSELSALEKQKDekitQQEEKYKALIQNLEKDKQRLAMNHEQD 1222
Cdd:pfam15742 215 RIQQQEAQL--------KQLENEKRKSDEHLKSNQELSEKLSSLQQEKE----ALQEELQQVLKQLDVHVRKYNEKHHHH 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1223 KEQLiqklnfekdeaiQTALDEFKLERELVEkellEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQL 1302
Cdd:pfam15742 283 KAKL------------RRAKDRLVHEVEQRD----ERIKQLENEIGILQQQSEKEKAFQKQVTAQNEILLLEKRKLLEQL 346
|
....*
gi 157824101 1303 EEQEK 1307
Cdd:pfam15742 347 TEQEE 351
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
763-1130 |
2.57e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 42.65 E-value: 2.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 763 LYSSVINAIDSRRMQDTSTRGNEGFGDRAALHVQLEKCRVAAQDSHISIQTIKDDlchfrtFVQKEQCDlsNYLKCTAVE 842
Cdd:TIGR00618 517 RQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS------FSILTQCD--NRSKEDIPN 588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 843 IRNIIDKVKCSLEITLKEKHQQ--ELQSLKIEYECKLNTLEKDSEENvnkilKLKEDLVSLEEALQNKDSEFAIIKHEKD 920
Cdd:TIGR00618 589 LQNITVRLQDLTEKLSEAEDMLacEQHALLRKLQPEQDLQDVRLHLQ-----QCSQELALKLTALHALQLTLTQERVREH 663
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 921 AIVCMQHEKdQKLLEMENIMHTQNSEIKELKQSREMVLEDLKKLHD--EKIESLRAEFQcleqnhlkELEDTLHIRHTEe 998
Cdd:TIGR00618 664 ALSIRVLPK-ELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLREleTHIEEYDREFN--------EIENASSSLGSD- 733
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 999 FEKVITDHKVSLEKLKKENQQKIDQMLESHASAIQE------KEQQLQELKVKVSDLSDMRCKLEVELALKEAETDE--- 1069
Cdd:TIGR00618 734 LAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEvtaalqTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeip 813
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157824101 1070 ----IKILLEESRTQQKETLKSLLEQETENLrTEINKLNQKIHDNSESYQVGLSELRSLMTIEKD 1130
Cdd:TIGR00618 814 sdedILNLQCETLVQEEEQFLSRLEEKSATL-GEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
860-1346 |
2.75e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 42.58 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 860 EKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiikhekdaiVCMQHEKDQKLLEMENi 939
Cdd:PRK01156 269 LEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAE-----------INKYHAIIKKLSVLQK- 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 940 MHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAefqcLEQNHLKeledtlhIRHTEEFEKVITDHKVSLEKLKKENQQ 1019
Cdd:PRK01156 337 DYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKS----IESLKKK-------IEEYSKNIERMSAFISEILKIQEIDPD 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1020 KIDQMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAE-----------TDEIKILLEESRTQqketlKSL 1088
Cdd:PRK01156 406 AIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgttlgEEKSNHIINHYNEK-----KSR 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1089 LEQETENLRTEINKLNQKIHDnsesyQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKL 1168
Cdd:PRK01156 481 LEEKIREIEIEVKDIDEKIVD-----LKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRY 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1169 KEQIVELQTKLNSELSALEKQKD----EKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEA--IQTAL 1242
Cdd:PRK01156 556 KSLKLEDLDSKRTSWLNALAVISlidiETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEAnnLNNKY 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1243 DEFKLERELVEkELLEKVKHLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFLEQLEEQ-EKRKNEEMQNVRTSLI 1321
Cdd:PRK01156 636 NEIQENKILIE-KLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRaRLESTIEILRTRINEL 714
|
490 500
....*....|....*....|....*.
gi 157824101 1322 AEQQTNFNTVLtrEKMRK-ENIINDL 1346
Cdd:PRK01156 715 SDRINDINETL--ESMKKiKKAIGDL 738
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
859-1040 |
2.81e-03 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 42.44 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 859 KEKHQQELQSLKIEYECKLNTLEKDSEENVNK-ILKLKEDLVSLEEALQN-KDSEFaiiKHEKDAIvcMQHEKDQKLLEM 936
Cdd:pfam09731 256 RIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSlIAHAHREIDQLSKKLAElKKREE---KHIERAL--EKQKEELDKLAE 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 937 ENIMHTQNSEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELEDTLHIRHTE---EFEKVITDhKVSLEK- 1012
Cdd:pfam09731 331 ELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLVEQEIElqrEFLQDIKE-KVEEERa 409
|
170 180 190
....*....|....*....|....*....|....*..
gi 157824101 1013 --LKKENQQK-----IDQMLESHASAIQE--KEQQLQ 1040
Cdd:pfam09731 410 grLLKLNELLanlkgLEKATSSHSEVEDEnrKAQQLW 446
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
1165-1325 |
3.01e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 41.72 E-value: 3.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1165 EKKLKEQIVELqTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAM----NHEQDKEQLIQKLNFEKDEAIQT 1240
Cdd:pfam15905 151 QKKMSSLSMEL-MKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQleekLVSTEKEKIEEKSETEKLLEYIT 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1241 AL-------DEFKLERELVEKELLEKVKHLEnqIAKSpAFESAREDSSSLVAELQEK---LQEEKAKFLEQLEEQEKRKN 1310
Cdd:pfam15905 230 ELscvseqvEKYKLDIAQLEELLKEKNDEIE--SLKQ-SLEEKEQELSKQIKDLNEKcklLESEKEELLREYEEKEQTLN 306
|
170
....*....|....*
gi 157824101 1311 EEMQNVRTSLIAEQQ 1325
Cdd:pfam15905 307 AELEELKEKLTLEEQ 321
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
958-1356 |
3.29e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 42.15 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 958 LEDLKKLH-----DEKIESLRAEFQCLEQNHLKELEDtlHIRHTEEFE---KVITDHKV--SLEKLKKENQQKIDQML-- 1025
Cdd:pfam06160 31 LSKVKKLNltgetQEKFEEWRKKWDDIVTKSLPDIEE--LLFEAEELNdkyRFKKAKKAldEIEELLDDIEEDIKQILee 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1026 --------ESHASAIQEKEQQLQELKvkvSDLSDMRCKLEVELALKEAETDEIKILLE--ESRTQQ------KETLKSLl 1089
Cdd:pfam06160 109 ldelleseEKNREEVEELKDKYRELR---KTLLANRFSYGPAIDELEKQLAEIEEEFSqfEELTESgdyleaREVLEKL- 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1090 EQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMT--IEKDQCISELISrhEEESNILKAELDSVTALHHQ-----AF 1162
Cdd:pfam06160 185 EEETDALEELMEDIPPLYEELKTELPDQLEELKEGYRemEEEGYALEHLNV--DKEIQQLEEQLEENLALLENleldeAE 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1163 EIEKKLKEQIVELQTKLNSELSA---LEKQKDEkITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKD-EAI 1238
Cdd:pfam06160 263 EALEEIEERIDQLYDLLEKEVDAkkyVEKNLPE-IEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGLEKQlEEL 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1239 QTALDEFKL---ERELVEKELLEKVKHLENQIAKspafesaredssslVAELQEKLQEEkakfLEQLEEQEKRKNEEMQN 1315
Cdd:pfam06160 342 EKRYDEIVErleEKEVAYSELQEELEEILEQLEE--------------IEEEQEEFKES----LQSLRKDELEAREKLDE 403
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 157824101 1316 VRTSLIAeqqtnfntvlTREKMRKENI----------INDLSDKLKSTMQQ 1356
Cdd:pfam06160 404 FKLELRE----------IKRLVEKSNLpglpesyldyFFDVSDEIEDLADE 444
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1075-1367 |
3.72e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1075 EESRTQQKETLKS--LLEQETENLrteinKLNQKIHDNSESYQVGLSELRSLMTIEkdqciselisrHEEESNILKAELD 1152
Cdd:COG3206 80 DSPLETQIEILKSrpVLERVVDKL-----NLDEDPLGEEASREAAIERLRKNLTVE-----------PVKGSNVIEISYT 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1153 SVTAlhHQAFEIEKKLKEQIVELQTKLNSELSaleKQKDEKITQQEEKYKALIQNLEKDKQRLAMNH-----EQDKEQLI 1227
Cdd:COG3206 144 SPDP--ELAAAVANALAEAYLEQNLELRREEA---RKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlSEEAKLLL 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1228 QKLNfekdeAIQTALDEFKLERELVE------KELLEKVKHLENQIAKSPAFESAREDSSSLVAELQE------------ 1289
Cdd:COG3206 219 QQLS-----ELESQLAEARAELAEAEarlaalRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAElsarytpnhpdv 293
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157824101 1290 -KLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTnfntvLTREKMRKENIINDLSDKLkSTMQQQERDKDLIESL 1367
Cdd:COG3206 294 iALRAQIAALRAQLQQEAQRILASLEAELEALQAREAS-----LQAQLAQLEARLAELPELE-AELRRLEREVEVAREL 366
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
844-1370 |
3.91e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 42.13 E-value: 3.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 844 RNIIDKVKCSLEITLKEKHQQELQSLKI-EYECKL----NTLEKDSEENVNKILKLKEDLVSLeeaLQNKDSEFAIIKHE 918
Cdd:PTZ00440 166 KNDLDNLIIVLENPEKYNVRKTLYDEKFnEYKNKKeafyNCLKNKKEDYDKKIKKINNEIRKL---LKNIKCTGNMCKTD 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 919 KDAIVCMQHEKDQKLLEMENIMHTQNsEIKELKQSREMVLEDLKKLHDEKIESLRAEFQCLEQNHLKELED--TLHIRHT 996
Cdd:PTZ00440 243 TYVDMVELYLLRVNEVPSNNYDNYLN-RAKELLESGSDLINKIKKELGDNKTIYSINFIQEEIGDIIKRYNfhLKKIEKG 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 997 EEFEKVITDHKVSLEKLKKENQQKI-------------DQMLESHASAIQEKEQQLQELKVKVsdLSDMRCKLEVELALK 1063
Cdd:PTZ00440 322 KEYIKRIQNNNIPPQVKKDELKKKYfesakhyasfkfsLEMLSMLDSLLIKKEKILNNLFNKL--FGDLKEKIETLLDSE 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1064 EAETD------EIKILLEESRTQQKETlKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQ---CIS 1134
Cdd:PTZ00440 400 YFISKytniisLSEHTLKAAEDVLKEN-SQKIADYALYSNLEIIEIKKKYDEKINELKKSINQLKTLISIMKSFydlIIS 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1135 ELISRHEEESNILK--AELDSVTALHHQAFEIEKKLK-------------EQIVELQTKLNSELSALE--KQKDEKITQQ 1197
Cdd:PTZ00440 479 EKDSMDSKEKKESSdsNYQEKVDELLQIINSIKEKNNivnnnfkniedyyITIEGLKNEIEGLIELIKyyLQSIETLIKD 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1198 EEKYKALI-----------QNLEKDKQRLAMNHE-----QDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELLEKVK 1261
Cdd:PTZ00440 559 EKLKRSMKndiknkikyieENVDHIKDIISLNDEidniiQQIEELINEALFNKEKFINEKNDLQEKVKYILNKFYKGDLQ 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1262 HLENQIAKSPAFESAREDSSSLVAELQEKLQEEKAKFleqlEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKEN 1341
Cdd:PTZ00440 639 ELLDELSHFLDDHKYLYHEAKSKEDLQTLLNTSKNEY----EKLEFMKSDNIDNIIKNLKKELQNLLSLKENIIKKQLNN 714
|
570 580
....*....|....*....|....*....
gi 157824101 1342 IINDLSDKLKSTMQQQERDKDLIESLSED 1370
Cdd:PTZ00440 715 IEQDISNSLNQYTIKYNDLKSSIEEYKEE 743
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1122-1261 |
3.92e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.74 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1122 RSLMTIEKDQcISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKY 1201
Cdd:PRK00409 508 KKLIGEDKEK-LNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEA 586
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1202 KALIQNLekdKQRLAMNHEQDKEQLIQklnfEKDEAIQTALDEFKlERELVEKELLEKVK 1261
Cdd:PRK00409 587 DEIIKEL---RQLQKGGYASVKAHELI----EARKRLNKANEKKE-KKKKKQKEKQEELK 638
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
854-1171 |
4.73e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.81 E-value: 4.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 854 LEITLKEKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQNKDSEfaiikhekdaivcmQHEKDQKL 933
Cdd:PLN02939 65 LQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDG--------------EQLSDFQL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 934 LEMENIMHTQNSEIKELKQSREMVLEDLKKLHDEKiESLRAEFQCLEQN----------------HLKELEDTLHIRHTE 997
Cdd:PLN02939 131 EDLVGMIQNAEKNILLLNQARLQALEDLEKILTEK-EALQGKINILEMRlsetdariklaaqekiHVEILEEQLEKLRNE 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 998 EFEKVITDHKV------SLEKLKKENQQKID--QMLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDE 1069
Cdd:PLN02939 210 LLIRGATEGLCvhslskELDVLKEENMLLKDdiQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSK 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1070 IKILLEESRTQQKETLKSLLEQETENLRTEINKL--NQKIHDNSESYQVGLSELR-SLMTIEKDQCISELISRHEEESNI 1146
Cdd:PLN02939 290 LSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLdqNQDLRDKVDKLEASLKEANvSKFSSYKVELLQQKLKLLEERLQA 369
|
330 340
....*....|....*....|....*....
gi 157824101 1147 LKAELDSVTALHHQAF----EIEKKLKEQ 1171
Cdd:PLN02939 370 SDHEIHSYIQLYQESIkefqDTLSKLKEE 398
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
944-1211 |
4.74e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 41.05 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 944 NSEIKELKQSREMVLEDLKKL---HDEKIESLRAEFQCLEQnhLKELEDtlhirhteEFEKVITDHKVSLEKLKKENQQK 1020
Cdd:COG1340 21 REEIEELKEKRDELNEELKELaekRDELNAQVKELREEAQE--LREKRD--------ELNEKVKELKEERDELNEKLNEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1021 IDQmLESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAET---DEIKILLEESRTQQKETLKSL----LEQET 1093
Cdd:COG1340 91 REE-LDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKelvEKIKELEKELEKAKKALEKNEklkeLRAEL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1094 ENLRTEINKLNQKIHDNSESYQvglselrslmtiEKDQCISELISRHEEesniLKAELDsvtALHHQAFEIEKK---LKE 1170
Cdd:COG1340 170 KELRKEAEEIHKKIKELAEEAQ------------ELHEEMIELYKEADE----LRKEAD---ELHKEIVEAQEKadeLHE 230
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 157824101 1171 QIVELQTKLNSELSALEKQKDEKITQQEEKYKALIQNLEKD 1211
Cdd:COG1340 231 EIIELQKELRELRKELKKLRKKQRALKREKEKEELEEKAEE 271
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
997-1472 |
4.79e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 4.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 997 EEFEKvITDHKVSLEKLKKENQQKIDQ---MLESHASAIQEkeqqLQELKVKVSDLSDMRCKLEVELALKEAETDEIKIL 1073
Cdd:pfam05483 85 KEAEK-IKKWKVSIEAELKQKENKLQEnrkIIEAQRKAIQE----LQFENEKVSLKLEEEIQENKDLIKENNATRHLCNL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1074 LEES--RTQQKETLKSLLEQETENLRTEINKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAEL 1151
Cdd:pfam05483 160 LKETcaRSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKE 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1152 DSVTALHHQAFEIEKKLKEqivelqtklnseLSALEKQKDEKITQQEEKYKALIQNLekdKQRLAMNHEQDKEQLIQKLN 1231
Cdd:pfam05483 240 KQVSLLLIQITEKENKMKD------------LTFLLEESRDKANQLEEKTKLQDENL---KELIEKKDHLTKELEDIKMS 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1232 FEKDEAIQTALDEfklERELVEKELLEKVKHLENQIAKSpafESAREDSSSLVAELQ------EKLQEEKAKFLEQLEEQ 1305
Cdd:pfam05483 305 LQRSMSTQKALEE---DLQIATKTICQLTEEKEAQMEEL---NKAKAAHSFVVTEFEattcslEELLRTEQQRLEKNEDQ 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1306 EKRKNEEMQNVRTSLiaEQQTNFN-----------TVLT-REKMRKENI-INDLSDKLKSTMQQ-----QERDKDlIESL 1367
Cdd:pfam05483 379 LKIITMELQKKSSEL--EEMTKFKnnkeveleelkKILAeDEKLLDEKKqFEKIAEELKGKEQElifllQAREKE-IHDL 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1368 SEDRARLLEEKKKLEEEVSKLRTSsvlpsapvLAAPELYGAcapELPGEPERSAMETTDEGRVDSAMETSMMSVQENMLS 1447
Cdd:pfam05483 456 EIQLTAIKTSEEHYLKEVEDLKTE--------LEKEKLKNI---ELTAHCDKLLLENKELTQEASDMTLELKKHQEDIIN 524
|
490 500
....*....|....*....|....*
gi 157824101 1448 EEKQRIMLLERTLQLKEEENKRLNQ 1472
Cdd:pfam05483 525 CKKQEERMLKQIENLEEKEMNLRDE 549
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
860-1361 |
5.25e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.70 E-value: 5.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 860 EKHQQELQSLKIEYECKLNTLEKDSEENVNKILKLKEDLVSLEEALQ--------------NKDSEFAIIKHEKDAIVCM 925
Cdd:pfam01576 425 ERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQdtqellqeetrqklNLSTRLRQLEDERNSLQEQ 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 926 QHEKDQKLLEMENIMHTQNSEIKELKQSREMVLEDLkklhdEKIESLRAEFQcleqnhlKELEDTlhirHTEEFEKVITD 1005
Cdd:pfam01576 505 LEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL-----EALEEGKKRLQ-------RELEAL----TQQLEEKAAAY 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1006 HKvsLEKLKKENQQKIDQML------ESHASAIQEKE----QQLQELKVKVSDLSDMRCKLEVELALKEA---------- 1065
Cdd:pfam01576 569 DK--LEKTKNRLQQELDDLLvdldhqRQLVSNLEKKQkkfdQMLAEEKAISARYAEERDRAEAEAREKETralslarale 646
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1066 ETDEIKILLEESRTQQK--------------------ETLKSLLEQETENLRTEINKLnqkiHDNSESYQVGLSELRSLM 1125
Cdd:pfam01576 647 EALEAKEELERTNKQLRaemedlvsskddvgknvhelERSKRALEQQVEEMKTQLEEL----EDELQATEDAKLRLEVNM 722
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1126 TIEKDQCISELISRHEEESNILKAELDSVTALHHQaFEIEKKLKEQIVELQTKLNSELSALEKQKDEKITQQEEKYKAL- 1204
Cdd:pfam01576 723 QALKAQFERDLQARDEQGEEKRRQLVKQVRELEAE-LEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLk 801
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1205 -IQNLEKDKQR-LAMNHEQDKEQLIQKLNFEKD------EAIQTALDEFKLER--ELVEKELLEKVKHLENQIAKSPAFE 1274
Cdd:pfam01576 802 kLQAQMKDLQReLEEARASRDEILAQSKESEKKlknleaELLQLQEDLAASERarRQAQQERDELADEIASGASGKSALQ 881
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1275 SAREDSSSLVAELQEKLQEEKAKfLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENiiNDLSDKLkSTM 1354
Cdd:pfam01576 882 DEKRRLEARIAQLEEELEEEQSN-TELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQN--KELKAKL-QEM 957
|
....*..
gi 157824101 1355 QQQERDK 1361
Cdd:pfam01576 958 EGTVKSK 964
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
940-1253 |
6.78e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 40.66 E-value: 6.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 940 MHTQNSEIKELKQSREMVLEDLKKLhDEKIESLRAEFQCLEQNhLKELEdtlhirhtEEFEKVITDHKVSLEKLKKENQQ 1019
Cdd:COG4372 40 LDKLQEELEQLREELEQAREELEQL-EEELEQARSELEQLEEE-LEELN--------EQLQAAQAELAQAQEELESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1020 KidqmlESHASAIQEKEQQLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKETLKSLLEQETENLRTE 1099
Cdd:COG4372 110 A-----EELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1100 INKLNQKIHDNSESYQVGLSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKL 1179
Cdd:COG4372 185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 157824101 1180 NSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVE 1253
Cdd:COG4372 265 LAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAE 338
|
|
| HlpA |
COG2825 |
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ... |
1178-1270 |
7.02e-03 |
|
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442073 [Multi-domain] Cd Length: 171 Bit Score: 39.05 E-value: 7.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1178 KLNSELSALEKQKDEKITQQEEKYKALIQNLEKDKQRLAMNHEQDKEQLIQKLNFEKDEAIQTALDEFKLERELVEKELL 1257
Cdd:COG2825 43 AAQKKLEKEFKKRQAELQKLEKELQALQEKLQKEAATLSEEERQKKERELQKKQQELQRKQQEAQQDLQKRQQELLQPIL 122
|
90
....*....|...
gi 157824101 1258 EKVKHLENQIAKS 1270
Cdd:COG2825 123 EKIQKAIKEVAKE 135
|
|
| GOLGA2L5 |
pfam15070 |
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ... |
1010-1306 |
7.10e-03 |
|
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.
Pssm-ID: 464485 [Multi-domain] Cd Length: 521 Bit Score: 40.82 E-value: 7.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1010 LEKLKKEN---QQKIDQMLESHASAIQEKEQ---QLQELKVKVSDLSDMRCKLEVELALKEAETDEIKILLEESRTQQKE 1083
Cdd:pfam15070 17 AENLKEEGavwQQKMQQLSEQVRTLREEKERsvsQVQELETSLAELKNQAAVPPAEEEQPPAGPSEEEQRLQEEAEQLQK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1084 TLKSL----------------LEQETENLRTEINKLNQKIHDNSESYQvglselRSLMTIEKDQC-ISELISRHEEESNI 1146
Cdd:pfam15070 97 ELEALagqlqaqvqdneqlsrLNQEQEQRLLELERAAERWGEQAEDRK------QILEDMQSDRAtISRALSQNRELKEQ 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1147 LkAELDS------------VTALH---HQAFEIEKKLKeqivELQTKLNS--ELSALEKQKDEKITQQEEKYKALIQNLE 1209
Cdd:pfam15070 171 L-AELQNgfvkltnenmelTSALQseqHVKKELAKKLG----QLQEELGElkETLELKSQEAQSLQEQRDQYLAHLQQYV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1210 KDKQRLAMNHEQDKEQLIQklnfekdeaiQTALDEfKLERELVEKELLEKVKHLENQIAKSpAFESAREDSSSLVAELQE 1289
Cdd:pfam15070 246 AAYQQLASEKEELHKQYLL----------QTQLMD-RLQHEEVQGKVAAEMARQELQETQE-RLEALTQQNQQLQAQLSL 313
|
330
....*....|....*..
gi 157824101 1290 KLQEEKAKFLEQLEEQE 1306
Cdd:pfam15070 314 LANPGEGDGLESEEEEE 330
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
1071-1318 |
8.09e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 40.68 E-value: 8.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1071 KILLEESRTQQKETLKSLLEQ---ETENLRTEINklNQKIHDNSESYQV---GLSELRSLMTIE----------KDQCIS 1134
Cdd:PRK05771 8 KVLIVTLKSYKDEVLEALHELgvvHIEDLKEELS--NERLRKLRSLLTKlseALDKLRSYLPKLnplreekkkvSVKSLE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1135 ELISRHEEESNILkaeLDSVTALHHQAFEIE---KKLKEQIVELQ--TKLNSELSAL-------------EKQKDEKITQ 1196
Cdd:PRK05771 86 ELIKDVEEELEKI---EKEIKELEEEISELEneiKELEQEIERLEpwGNFDLDLSLLlgfkyvsvfvgtvPEDKLEELKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1197 QEEKYKALIQNLEKDKQRLAM----NHEQDKEQLIQKLNFEKDE-----AIQTALDEFKLERELVEKELlekvKHLENQI 1267
Cdd:PRK05771 163 ESDVENVEYISTDKGYVYVVVvvlkELSDEVEEELKKLGFERLEleeegTPSELIREIKEELEEIEKER----ESLLEEL 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 157824101 1268 akspafesaredssslvAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRT 1318
Cdd:PRK05771 239 -----------------KELAKKYLEELLALYEYLEIELERAEALSKFLKT 272
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1118-1474 |
8.24e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.79 E-value: 8.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1118 LSELRSLMTIEKDQCISELISRHEEESNILKAELDSVTALHHQAFEIEKKLKEQIVELQTKLnSELSALEKQKD---EKI 1194
Cdd:PRK02224 189 LDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR-EELETLEAEIEdlrETI 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1195 TQQEEKYKALIQNLEkDKQRLAMNHEQDKEQLIQKLNFEK--DEAIQTALDEFKLERELVEKELLEK---VKHLENQIak 1269
Cdd:PRK02224 268 AETEREREELAEEVR-DLRERLEELEEERDDLLAEAGLDDadAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEA-- 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1270 spafESAREDSSSLVAELQEKlqEEKAKFLEqleeqekrknEEMQNVRTSlIAEQQTnfntvlTREKMRKEniINDLSDK 1349
Cdd:PRK02224 345 ----ESLREDADDLEERAEEL--REEAAELE----------SELEEAREA-VEDRRE------EIEELEEE--IEELRER 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1350 LKSTMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRtSSVLPSAPVLAA---PElygaCAPELPGEPERSAMETTD 1426
Cdd:PRK02224 400 FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR-ERVEEAEALLEAgkcPE----CGQPVEGSPHVETIEEDR 474
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 157824101 1427 EGRVDSAMETSMMSVQENMLSEEKQRIMLL---ERTLQLKEEENKRLNQRL 1474
Cdd:PRK02224 475 ERVEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELI 525
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
885-1373 |
9.84e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 9.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 885 EENVNKILKLKEDLVSLEEALQNKDSEFAIIKHE--KDAIVCMQHEKDQKLLEMEnimhTQNSEIKELKQSREMVLEDLK 962
Cdd:COG4913 258 RELAERYAAARERLAELEYLRAALRLWFAQRRLEllEAELEELRAELARLEAELE----RLEARLDALREELDELEAQIR 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 963 KLHDEKIESLRAEFQCLEQnHLKELEDTLhirhtEEFEKVITDHKVSLEKLKK---ENQQKIDQMLESHASAIQEKEQQL 1039
Cdd:COG4913 334 GNGGDRLEQLEREIERLER-ELEERERRR-----ARLEALLAALGLPLPASAEefaALRAEAAALLEALEEELEALEEAL 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1040 QELKVKVSDLSDMRCKLEVEL-----------------------ALKEAETD------EIKILLEESRTQ---------Q 1081
Cdd:COG4913 408 AEAEAALRDLRRELRELEAEIaslerrksniparllalrdalaeALGLDEAElpfvgeLIEVRPEEERWRgaiervlggF 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1082 KETLksLLEQETEN-LRTEINKLNQKIHDNSESYQVGLSELRsLMTIEKDQCISELISRHEEESNILKAEL--------- 1151
Cdd:COG4913 488 ALTL--LVPPEHYAaALRWVNRLHLRGRLVYERVRTGLPDPE-RPRLDPDSLAGKLDFKPHPFRAWLEAELgrrfdyvcv 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1152 DSVTALHHQAFEIEKklkeqivELQTKLNSelSALEKQKDEKITQQ-------EEKYKALIQNLEKDKQRLAmNHEQDKE 1224
Cdd:COG4913 565 DSPEELRRHPRAITR-------AGQVKGNG--TRHEKDDRRRIRSRyvlgfdnRAKLAALEAELAELEEELA-EAEERLE 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157824101 1225 QL--IQKLNFEKDEAIQTALDEFKLERELveKELLEKVKHLENQIAkspafesAREDSSSLVAELQEKLQEEKAKfLEQL 1302
Cdd:COG4913 635 ALeaELDALQERREALQRLAEYSWDEIDV--ASAEREIAELEAELE-------RLDASSDDLAALEEQLEELEAE-LEEL 704
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157824101 1303 EEQEKRKNEEMQNVRTSL--IAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRAR 1373
Cdd:COG4913 705 EEELDELKGEIGRLEKELeqAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDA 777
|
|
| |
