|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00309 |
PTZ00309 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
31-510 |
1.40e-94 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 240353 [Multi-domain] Cd Length: 542 Bit Score: 305.91 E-value: 1.40e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 31 VSIILLGATGDLAKKYLWQGLFQLYLDeaGK-GHSFSFHGAALTAPQQGQKLMDKALeslscPKDLVPSRCDELKA-QFL 108
Cdd:PTZ00309 55 LTIIVLGASGDLAKKKTFPALFQLYCE--GLlPSEVNIVGYARSKMSDVERWKKETL-----ARFFKRLDDRECHLeQFL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 109 QLSQYR--QLKTVEDYQTLNKDIETQVQQDGLWEAG--RVFYFSVPPFAYADIARNINSSCRPHPGaWLRVVFEKPFGHD 184
Cdd:PTZ00309 128 KHISYIsgSYDEDEDFKRLNKLIERMEEAFQGPEKGgnRLFYLALPPSVFASVCEGIHRGCMSKNG-WVRVIVEKPFGRD 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 185 HLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGV 264
Cdd:PTZ00309 207 LESSEELSNQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANR-VFEPLWNRNNIACVQITFKEDIGTEGRGGYFDSYGI 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 265 IRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQ----VRQELQKPDGfqSLTP 340
Cdd:PTZ00309 286 IRDVMQNHLLQILALLAME-KPVSLSAEDIRDEKVKVLKCIEPIKMEECVLGQYTASADGsipgYLEDEGVPKD--STTP 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 341 TFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNrayctqgerhwVPErsrclpqqIVFY---IGHGEL----- 412
Cdd:PTZ00309 363 TFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFKG-----------VDE--------FRPSgddTQRNELviraq 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 413 GHPAILVSKNLFKPSLPAQSWKGVQDQPGLHLFGrplsdyyayrpVREQDAYSTLLSHIFHCRKESFITTENLLASWVFW 492
Cdd:PTZ00309 424 PSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYN-----------VRLPDAYERLILDALLGDSTNFVRKDELDVAWRIF 492
|
490 500
....*....|....*....|
gi 157821675 493 TPLLDSL-SFEV-PRLYPGG 510
Cdd:PTZ00309 493 TPLLHQIdRGEVkPEPYPFG 512
|
|
| pgl |
TIGR01198 |
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ... |
562-797 |
1.20e-90 |
|
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273494 [Multi-domain] Cd Length: 233 Bit Score: 284.65 E-value: 1.20e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 562 ITAWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGhySFPWAYTHLWLVDERCVPLSDPDSNFQG 641
Cdd:TIGR01198 1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALAAQ--PLDWSRIHLFLGDERYVPLDHADSNTGL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 642 LQAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVAN---SSFDLVLLGMGTDGHTASLFPQSPRGLDG 718
Cdd:TIGR01198 79 AREALLDRVAIPASNIHPMPTEL-----SDIEEAAELYEQELAAAFQPivfPVFDLLLLGMGPDGHTASLFPHTPALQET 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 719 DQLV-VLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPlSGQLVWYMDYEAFLG 797
Cdd:TIGR01198 154 ERLVtVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEAEPYPLPAAGVLH-SGKTLWLLDYAAARK 232
|
|
| Glucosamine_iso |
pfam01182 |
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; |
564-788 |
3.61e-83 |
|
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
Pssm-ID: 460101 [Multi-domain] Cd Length: 222 Bit Score: 264.48 E-value: 3.61e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 564 AWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQ 643
Cdd:pfam01182 1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLDWSRVHVFWGDERCVPPDDPDSNYGMAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 644 AHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVANSS---FDLVLLGMGTDGHTASLFPQSPRGLDGDQ 720
Cdd:pfam01182 81 EALLSHVPIPASNVHPIPASA-----ADPEEAAAAYEAELRELLPDLElpvFDLVLLGMGPDGHTASLFPGSPALEETDR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 721 LVV-LTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV-GHEPKKWPISGVVPLSGQLVW 788
Cdd:pfam01182 156 LVVaVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADA---LRRAlAGDPDPLPAALVRPGAGETVW 222
|
|
| zwf |
TIGR00871 |
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ... |
33-510 |
4.44e-83 |
|
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273312 [Multi-domain] Cd Length: 487 Bit Score: 273.43 E-value: 4.44e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLY----LDEagkghSFSFHGAALTAPQQGQ--KLMDKALESlSCPKDLvpsrcDELKAQ 106
Cdd:TIGR00871 5 LVIFGASGDLARKKLFPALYRLFrnglLPP-----DFRIVGVARRDWSVEEfrKVVREAIIK-FETDEI-----DEQWDE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 107 FLQLSQYR--QLKTVEDYQTLNKDIEtQVQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHD 184
Cdd:TIGR00871 74 FAQRLSYVsgDVDDDESYDSLAELLE-QLDKTYGTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQGKWSRVVVEKPFGHD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 185 HLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGV 264
Cdd:TIGR00871 153 LASAQELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQ-IFEPLWNRRYIDHVQITVAESFGVEGRGGYYDKSGA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 265 IRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQK--SNAILGQYQAysGQVRQElQKP-----DGF-- 335
Cdd:TIGR00871 232 LRDMVQNHLLQLLALVAME-PPVSFDADSIRDEKVKVLKALRPIDPddNNTVRGQYGA--GEIGGV-SVPgyleeEGVdk 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 336 QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNrayctqgerhwVP-------ERSRCLPQQIVFYIG 408
Cdd:TIGR00871 308 DSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRD-----------VPsllfkanERDANPRNALVIRIQ 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 409 HGElghpAILVSKNLFKPSLPAQswkgVQDqpgLHLFGRPLSDYYAYRPvreqDAYSTLLSHIFHCRKESFITTENLLAS 488
Cdd:TIGR00871 377 PDE----GVYLKFNAKKPGLNFE----TRP---VKLDFSYASRFGELLP----EAYERLLLDALLGDHTLFARDDEVEEA 441
|
490 500
....*....|....*....|....*
gi 157821675 489 WVFWTPLLDSL---SFEVPRLYPGG 510
Cdd:TIGR00871 442 WRIVTPILEAWaanKGPSPPNYPAG 466
|
|
| 6PGL |
cd01400 |
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ... |
567-790 |
1.47e-78 |
|
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.
Pssm-ID: 238694 [Multi-domain] Cd Length: 219 Bit Score: 252.10 E-value: 1.47e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 567 EELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGhYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHL 646
Cdd:cd01400 1 EALAEALADRIAEALAAAIAKRGRFSLALSGGSTPKPLYELLAAA-PALDWSKVHVFLGDERCVPPDDPDSNYRLAREAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 647 LQHVRVPYYNIHPMPVHLHqrlcaeEDQGAQTYASEISALVANS-SFDLVLLGMGTDGHTASLFPQSPR-GLDGDQLVVL 724
Cdd:cd01400 80 LSHVAIPAANIHPIPTELG------PEDAAAAYEKELRALFGGVpPFDLVLLGMGPDGHTASLFPGHPAlLEETDRLVVA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157821675 725 TE-SPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSGQLVWYM 790
Cdd:cd01400 154 VTdSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEA---LKRAlaGPDPEELPAARVLPRPGEVLWFL 219
|
|
| Zwf |
COG0364 |
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ... |
33-380 |
1.98e-78 |
|
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440133 [Multi-domain] Cd Length: 495 Bit Score: 261.55 E-value: 1.98e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLYLDeagkGH---SFSFHGAALTaPQQGQKLMDKALESLscpKDLVPSRCDELK-AQFL 108
Cdd:COG0364 12 LVIFGATGDLARRKLLPALYNLYRD----GLlpeGFRIIGVARR-DWSDEEFREEVREAL---EEFSRKPFDEEVwERFL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 109 QLSQYRQL--KTVEDYQTLNKDIEtqvQQDGLWEAG-RVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDH 185
Cdd:COG0364 84 ERLHYVSGdfTDPEGYERLKELLE---ELDEERTPGnRVFYLATPPSLFGPICENLGAAGLATEGGWRRVVIEKPFGHDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 186 LSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVI 265
Cdd:COG0364 161 ASARELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANA-LFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGAL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 266 RDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKS----NAILGQYQAysGQV--------RQElqkpD 333
Cdd:COG0364 240 RDMVQNHLLQLLCLVAME-PPASLDADAIRDEKVKVLRALRPITPEdvaeNTVRGQYTA--GWIggepvpgyREE----P 312
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 157821675 334 GF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKN 380
Cdd:COG0364 313 GVapDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKP 361
|
|
| G6PD_C |
pfam02781 |
Glucose-6-phosphate dehydrogenase, C-terminal domain; |
233-518 |
1.13e-64 |
|
Glucose-6-phosphate dehydrogenase, C-terminal domain;
Pssm-ID: 460694 Cd Length: 295 Bit Score: 217.69 E-value: 1.13e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 233 LWNRHHVERVEIILKETVDAGGRASFYEEYGVIRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKS- 311
Cdd:pfam02781 13 LWNRNYIDHVQITVAETLGVEGRGGYYDQAGALRDMVQNHLLQLLALVAME-PPVSFDAEDIRDEKVKVLRSLRPITPEd 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 312 ---NAILGQYQA--YSGQV----RQELQKPDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNra 382
Cdd:pfam02781 92 vedNVVRGQYGAgwIGGEPvpgyREEEGVPPD--SRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEIRIQFKD-- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 383 yctqgerhwVP-----ERSRCLPQQIVFYIGHGElghpAILVSKNLFKpslpaqswkgvqdqPGLHLFGRPLS---DYYA 454
Cdd:pfam02781 168 ---------VPhnlfrDPGTLPPNELVIRIQPDE----GIYLKFNAKV--------------PGLGMRLRPVEldfSYSD 220
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157821675 455 YRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLSFEVPRLYPGG----AENDHLLD 518
Cdd:pfam02781 221 RFGERIPEAYERLLLDVMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEKPPPYPAGswgpKAADELLA 288
|
|
| NagB |
COG0363 |
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ... |
566-794 |
4.14e-55 |
|
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440132 [Multi-domain] Cd Length: 248 Bit Score: 189.99 E-value: 4.14e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 566 PEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYS--FPWAYTHLWLVDERC-VPLSDPDSNFQGL 642
Cdd:COG0363 10 AEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEELARLHKEggLDWSRVHVFNLDEYVgLPPDHPQSNRRFM 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 643 QAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPRGLDGDQLV 722
Cdd:COG0363 90 REALLDHVDIPPENIHIPDGEA-----EDPEAAAARYEALIAEA---GGIDLQLLGIGEDGHIAFNFPGSPFLSETDRVV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 723 VLTESPFR------------PHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSgQLVW 788
Cdd:COG0363 162 TLDESTRQanarffgsipkvPPQAITLGIPTIMKAREILLLATGENKAEA---VAAAleGPVTEEVPASILQGHP-NVTW 237
|
....*.
gi 157821675 789 YMDYEA 794
Cdd:COG0363 238 FLDEAA 243
|
|
| PLN02360 |
PLN02360 |
probable 6-phosphogluconolactonase |
567-794 |
3.17e-30 |
|
probable 6-phosphogluconolactonase
Pssm-ID: 166001 [Multi-domain] Cd Length: 268 Bit Score: 120.35 E-value: 3.17e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 567 EELISKLANDIEAAAVQAVRRFGKFHLALSGGSSpIALFQQLATGHY--SFPWAYTHLWLVDERCVPLSDPDSNFQGLQA 644
Cdd:PLN02360 20 DELSTDLAEYIAELSEASVKERGVFAIALSGGSL-ISFMGKLCEAPYnkTVDWAKWYIFWADERVVAKNHADSNYKLAKD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 645 HLLQHVRVPYYNIHPmpvhLHQRLCAEEdqGAQTYASEISALVANSS-----------FDLVLLGMGTDGHTASLFPQSP 713
Cdd:PLN02360 99 GLLSKVPVVPSHVYS----INDTVTAEE--AATDYEFAIRQLVKTRTigvsdisdcpkFDLILLGMGSDGHVASLFPNHP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 714 R-GLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTL-VSRVGHEP--KKWPISGVVPLSGQLVWY 789
Cdd:PLN02360 173 AlEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKANAVHLaIDDVTEGPdaPSLPARMVQPTKGKLVWF 252
|
....*
gi 157821675 790 MDYEA 794
Cdd:PLN02360 253 LDKPA 257
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00309 |
PTZ00309 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
31-510 |
1.40e-94 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 240353 [Multi-domain] Cd Length: 542 Bit Score: 305.91 E-value: 1.40e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 31 VSIILLGATGDLAKKYLWQGLFQLYLDeaGK-GHSFSFHGAALTAPQQGQKLMDKALeslscPKDLVPSRCDELKA-QFL 108
Cdd:PTZ00309 55 LTIIVLGASGDLAKKKTFPALFQLYCE--GLlPSEVNIVGYARSKMSDVERWKKETL-----ARFFKRLDDRECHLeQFL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 109 QLSQYR--QLKTVEDYQTLNKDIETQVQQDGLWEAG--RVFYFSVPPFAYADIARNINSSCRPHPGaWLRVVFEKPFGHD 184
Cdd:PTZ00309 128 KHISYIsgSYDEDEDFKRLNKLIERMEEAFQGPEKGgnRLFYLALPPSVFASVCEGIHRGCMSKNG-WVRVIVEKPFGRD 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 185 HLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGV 264
Cdd:PTZ00309 207 LESSEELSNQLEPLFDESQLYRIDHYLGKEMVQNLIVLRFANR-VFEPLWNRNNIACVQITFKEDIGTEGRGGYFDSYGI 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 265 IRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQ----VRQELQKPDGfqSLTP 340
Cdd:PTZ00309 286 IRDVMQNHLLQILALLAME-KPVSLSAEDIRDEKVKVLKCIEPIKMEECVLGQYTASADGsipgYLEDEGVPKD--STTP 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 341 TFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNrayctqgerhwVPErsrclpqqIVFY---IGHGEL----- 412
Cdd:PTZ00309 363 TFAAAVLHINNDRWEGVPFILEAGKALEERYVEIRIQFKG-----------VDE--------FRPSgddTQRNELviraq 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 413 GHPAILVSKNLFKPSLPAQSWKGVQDQPGLHLFGrplsdyyayrpVREQDAYSTLLSHIFHCRKESFITTENLLASWVFW 492
Cdd:PTZ00309 424 PSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYN-----------VRLPDAYERLILDALLGDSTNFVRKDELDVAWRIF 492
|
490 500
....*....|....*....|
gi 157821675 493 TPLLDSL-SFEV-PRLYPGG 510
Cdd:PTZ00309 493 TPLLHQIdRGEVkPEPYPFG 512
|
|
| pgl |
TIGR01198 |
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ... |
562-797 |
1.20e-90 |
|
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273494 [Multi-domain] Cd Length: 233 Bit Score: 284.65 E-value: 1.20e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 562 ITAWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGhySFPWAYTHLWLVDERCVPLSDPDSNFQG 641
Cdd:TIGR01198 1 VFSNSAELAEALAERIATKLQTALAERGQFSLALSGGRSPIALLEALAAQ--PLDWSRIHLFLGDERYVPLDHADSNTGL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 642 LQAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVAN---SSFDLVLLGMGTDGHTASLFPQSPRGLDG 718
Cdd:TIGR01198 79 AREALLDRVAIPASNIHPMPTEL-----SDIEEAAELYEQELAAAFQPivfPVFDLLLLGMGPDGHTASLFPHTPALQET 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 719 DQLV-VLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPlSGQLVWYMDYEAFLG 797
Cdd:TIGR01198 154 ERLVtVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEAEPYPLPAAGVLH-SGKTLWLLDYAAARK 232
|
|
| PRK05722 |
PRK05722 |
glucose-6-phosphate 1-dehydrogenase; Validated |
33-380 |
3.14e-83 |
|
glucose-6-phosphate 1-dehydrogenase; Validated
Pssm-ID: 235579 [Multi-domain] Cd Length: 495 Bit Score: 274.31 E-value: 3.14e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLYLDeagkGH---SFSFHGAALTA--PQQGQKLMDKALESLSCPKdlvpsRCDELKAQF 107
Cdd:PRK05722 12 LVIFGATGDLARRKLLPALYNLYKA----GLlpeDFRIIGVARRDwsDEDFREVVREALKEFARTP-----FDEEVWERF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 108 LQLSQYRQ--LKTVEDYQTLNKDIETQVQQDGLwEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDH 185
Cdd:PRK05722 83 LSRLYYVSgdVTDPESYERLKELLEELDEERGT-GGNRVFYLATPPSLFGTICENLAAAGLNEGGGWRRVVIEKPFGHDL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 186 LSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNrkAL-DGLWNRHHVERVEIILKETVDAGGRASFYEEYGV 264
Cdd:PRK05722 162 ASARELNDQVGEVFKEEQIYRIDHYLGKETVQNLLALRFAN--ALfEPLWNRNYIDHVQITVAETVGVEGRGGYYDKSGA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 265 IRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQ----KSNAILGQYQAysGQV--------RQELQKP 332
Cdd:PRK05722 240 LRDMVQNHLLQLLALVAME-PPASLDADSIRDEKVKVLRALRPITpedvKENTVRGQYTA--GWIggkpvpgyREEEGVN 316
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 157821675 333 DgfQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKN 380
Cdd:PRK05722 317 P--DSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPKKVTEIVIVFKP 362
|
|
| Glucosamine_iso |
pfam01182 |
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; |
564-788 |
3.61e-83 |
|
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
Pssm-ID: 460101 [Multi-domain] Cd Length: 222 Bit Score: 264.48 E-value: 3.61e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 564 AWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQ 643
Cdd:pfam01182 1 PDAEALAQALAERLAEALEAALAERGRFTLALSGGSTPKPLYELLAAAPARLDWSRVHVFWGDERCVPPDDPDSNYGMAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 644 AHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALVANSS---FDLVLLGMGTDGHTASLFPQSPRGLDGDQ 720
Cdd:pfam01182 81 EALLSHVPIPASNVHPIPASA-----ADPEEAAAAYEAELRELLPDLElpvFDLVLLGMGPDGHTASLFPGSPALEETDR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 721 LVV-LTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV-GHEPKKWPISGVVPLSGQLVW 788
Cdd:pfam01182 156 LVVaVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADA---LRRAlAGDPDPLPAALVRPGAGETVW 222
|
|
| zwf |
TIGR00871 |
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ... |
33-510 |
4.44e-83 |
|
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]
Pssm-ID: 273312 [Multi-domain] Cd Length: 487 Bit Score: 273.43 E-value: 4.44e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLY----LDEagkghSFSFHGAALTAPQQGQ--KLMDKALESlSCPKDLvpsrcDELKAQ 106
Cdd:TIGR00871 5 LVIFGASGDLARKKLFPALYRLFrnglLPP-----DFRIVGVARRDWSVEEfrKVVREAIIK-FETDEI-----DEQWDE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 107 FLQLSQYR--QLKTVEDYQTLNKDIEtQVQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHD 184
Cdd:TIGR00871 74 FAQRLSYVsgDVDDDESYDSLAELLE-QLDKTYGTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQGKWSRVVVEKPFGHD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 185 HLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGV 264
Cdd:TIGR00871 153 LASAQELNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQ-IFEPLWNRRYIDHVQITVAESFGVEGRGGYYDKSGA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 265 IRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQK--SNAILGQYQAysGQVRQElQKP-----DGF-- 335
Cdd:TIGR00871 232 LRDMVQNHLLQLLALVAME-PPVSFDADSIRDEKVKVLKALRPIDPddNNTVRGQYGA--GEIGGV-SVPgyleeEGVdk 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 336 QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNrayctqgerhwVP-------ERSRCLPQQIVFYIG 408
Cdd:TIGR00871 308 DSNTETFAALKLEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRD-----------VPsllfkanERDANPRNALVIRIQ 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 409 HGElghpAILVSKNLFKPSLPAQswkgVQDqpgLHLFGRPLSDYYAYRPvreqDAYSTLLSHIFHCRKESFITTENLLAS 488
Cdd:TIGR00871 377 PDE----GVYLKFNAKKPGLNFE----TRP---VKLDFSYASRFGELLP----EAYERLLLDALLGDHTLFARDDEVEEA 441
|
490 500
....*....|....*....|....*
gi 157821675 489 WVFWTPLLDSL---SFEVPRLYPGG 510
Cdd:TIGR00871 442 WRIVTPILEAWaanKGPSPPNYPAG 466
|
|
| PLN02539 |
PLN02539 |
glucose-6-phosphate 1-dehydrogenase |
29-496 |
3.03e-81 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 178154 [Multi-domain] Cd Length: 491 Bit Score: 268.90 E-value: 3.03e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 29 GHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTaPQQGQKLMDKALESLSCPKDlvpsRCDELKAQFL 108
Cdd:PLN02539 16 GCLSIIVLGASGDLAKKKTFPALFNLYRQGFLPPDEVHIFGYARS-KITDEELRDRIRGYLKDEKN----APAEAVSKFL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 109 QLSQYRQ--LKTVEDYQTLNKDI-ETQVQQDGLWEAG-RVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHD 184
Cdd:PLN02539 91 QLIKYVSgaYDSEEGFRRLDKEIsEHEISKNSAEGSSrRLFYLALPPSVYPPVCKMIKKCCMNKSGLWTRIVVEKPFGKD 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 185 HLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDgLWNRHHVERVEIILKETVDAGGRASFYEEYGV 264
Cdd:PLN02539 171 LESAEELSSQIGELFDESQLYRIDHYLGKELVQNLLVLRFANRFFLP-LWNRDNIANVQIVFREDFGTEGRGGYFDEYGI 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 265 IRDTLQNHLTEILTLVAMELPPNISSSaAVLQHKLQAFQALRGLQKSNAILGQYQAYsgqvRQELQKPDGfqSLTPTFAG 344
Cdd:PLN02539 250 IRDIIQNHLLQVLCLVAMEKPVSLKPE-HIRDEKVKVLQSVEPIKDEEVVLGQYEGY----RDDPTVPDD--SNTPTFAS 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 345 VLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNrayctqgerhwVP-ERSRCLPQqivfyighgelghpailvSKNL 423
Cdd:PLN02539 323 VVLRINNERWEGVPFILKAGKALDSRKAEIRVQFKD-----------VPgDIFKCQKQ------------------GRNE 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 424 F----KPSlPAQSWKGVQDQPGLHLFGRP----LSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPL 495
Cdd:PLN02539 374 FvirlQPS-EAMYMKLTVKQPGLEMSTVQseldLSYGQRYQDVVIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPL 452
|
.
gi 157821675 496 L 496
Cdd:PLN02539 453 L 453
|
|
| 6PGL |
cd01400 |
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ... |
567-790 |
1.47e-78 |
|
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.
Pssm-ID: 238694 [Multi-domain] Cd Length: 219 Bit Score: 252.10 E-value: 1.47e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 567 EELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGhYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHL 646
Cdd:cd01400 1 EALAEALADRIAEALAAAIAKRGRFSLALSGGSTPKPLYELLAAA-PALDWSKVHVFLGDERCVPPDDPDSNYRLAREAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 647 LQHVRVPYYNIHPMPVHLHqrlcaeEDQGAQTYASEISALVANS-SFDLVLLGMGTDGHTASLFPQSPR-GLDGDQLVVL 724
Cdd:cd01400 80 LSHVAIPAANIHPIPTELG------PEDAAAAYEKELRALFGGVpPFDLVLLGMGPDGHTASLFPGHPAlLEETDRLVVA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157821675 725 TE-SPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSGQLVWYM 790
Cdd:cd01400 154 VTdSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEA---LKRAlaGPDPEELPAARVLPRPGEVLWFL 219
|
|
| Zwf |
COG0364 |
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ... |
33-380 |
1.98e-78 |
|
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440133 [Multi-domain] Cd Length: 495 Bit Score: 261.55 E-value: 1.98e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLYLDeagkGH---SFSFHGAALTaPQQGQKLMDKALESLscpKDLVPSRCDELK-AQFL 108
Cdd:COG0364 12 LVIFGATGDLARRKLLPALYNLYRD----GLlpeGFRIIGVARR-DWSDEEFREEVREAL---EEFSRKPFDEEVwERFL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 109 QLSQYRQL--KTVEDYQTLNKDIEtqvQQDGLWEAG-RVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDH 185
Cdd:COG0364 84 ERLHYVSGdfTDPEGYERLKELLE---ELDEERTPGnRVFYLATPPSLFGPICENLGAAGLATEGGWRRVVIEKPFGHDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 186 LSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVI 265
Cdd:COG0364 161 ASARELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANA-LFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGAL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 266 RDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKS----NAILGQYQAysGQV--------RQElqkpD 333
Cdd:COG0364 240 RDMVQNHLLQLLCLVAME-PPASLDADAIRDEKVKVLRALRPITPEdvaeNTVRGQYTA--GWIggepvpgyREE----P 312
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 157821675 334 GF--QSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKN 380
Cdd:COG0364 313 GVapDSTTETFVALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKP 361
|
|
| PRK12853 |
PRK12853 |
glucose-6-phosphate dehydrogenase; |
33-517 |
1.44e-71 |
|
glucose-6-phosphate dehydrogenase;
Pssm-ID: 237233 [Multi-domain] Cd Length: 482 Bit Score: 242.50 E-value: 1.44e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLYLDEAgKGHSFSFHGAALTAPQQGQ--KLMDKALESLScPKDLVPSRCDelkaQFLQL 110
Cdd:PRK12853 11 LVIFGATGDLARRKLLPALYRLARAGL-LPEDLRIIGVGRDDWSDEQwrARVRESLRAFG-ADGFDDAVWD----RLAAR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 111 SQYRQ--LKTVEDYQTLNKDIETQVQqdglweagRVFYFSVPPFAYADIARNINSS-CRPhpgAWLRVVFEKPFGHDHLS 187
Cdd:PRK12853 85 LSYVQgdVTDPADYARLAEALGPGGN--------PVFYLAVPPSLFAPVVENLGAAgLLP---EGRRVVLEKPFGHDLAS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 188 AQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVIRD 267
Cdd:PRK12853 154 ARALNATLAKVFDEDQIYRIDHFLGKETVQNLLALRFANA-LLEPLWNRNHIDHVQITVAETLGVEGRGGFYDATGALRD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 268 TLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKSNAIL--GQYQAysGQV--------RQELQKPDGfqS 337
Cdd:PRK12853 233 MVQNHLLQLLALVAME-PPASFDADAVRDEKAKVLRAIRPLDPDDVHTvrGQYTA--GTVggepvpgyREEPGVDPD--S 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 338 LTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNRAYCTQGERHwvpersRCLPQQIVFYIGHGELGHPAI 417
Cdd:PRK12853 308 RTETFVALKLEIDNWRWAGVPFYLRTGKRLAERRTEIVITFKPVPHALFRGTG------VEPPNRLVIRLQPDEGISLEL 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 418 LVSknlfkpslpaqswkgvqdQPGLHLFGRPLSDYYAYR-PVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLL 496
Cdd:PRK12853 382 NVK------------------RPGPGMRLRPVELDADYAdDERPLEAYERLLLDVLRGDPTLFVRADEVEAAWRIVDPVL 443
|
490 500
....*....|....*....|....*..
gi 157821675 497 D--SLSFEVPRLYPGG----AENDHLL 517
Cdd:PRK12853 444 DawAADPVPPHEYPAGswgpAAADALL 470
|
|
| PLN02640 |
PLN02640 |
glucose-6-phosphate 1-dehydrogenase |
23-511 |
3.90e-70 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 215344 [Multi-domain] Cd Length: 573 Bit Score: 241.46 E-value: 3.90e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 23 QAQEFRGHVSIILLGATGDLAKKYLWQGLFQLYLdEAGKGHSFSFHGAALTAPQQgQKLMDKALESLSCPKDlVPSRCDE 102
Cdd:PLN02640 81 HAEKGESTLSITVVGASGDLAKKKIFPALFALFY-EDWLPENFTVFGYARTKLTD-EELRDMISSTLTCRID-QRENCGD 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 103 LKAQFLQLSQYR--QLKTVEDYQTLNKDIETQvqqdglwEAG----RVFYFSVPPFAYADIARNINSSCRPHPGaWLRVV 176
Cdd:PLN02640 158 KMDQFLKRCFYHsgQYDSEEDFAELNKKLKEK-------EAGklsnRLFYLSIPPNIFVDVVRCASLRASSENG-WTRVI 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 177 FEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRA 256
Cdd:PLN02640 230 VEKPFGRDSESSGELTRCLKQYLTEEQIFRIDHYLGKELVENLSVLRFSNL-VFEPLWSRNYIRNVQLIFSEDFGTEGRG 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 257 SFYEEYGVIRDTLQNHLTEILTLVAMELPPNISSSaAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQVR------QELQ 330
Cdd:PLN02640 309 GYFDNYGIIRDIMQNHLLQILALFAMETPVSLDAE-DIRNEKVKVLRSMKPLQLEDVIVGQYKGHSKGGKsypaytDDPT 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 331 KPDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKN-------RAYCTQGERhwvpersrcLPQQI 403
Cdd:PLN02640 388 VPKH--SLTPTFAAAALFINNARWDGVPFLMKAGKALHTRRAEIRVQFRHvpgnlykRNFGTDLDK---------ATNEL 456
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 404 VFYIGHGElghpAILVSKNLFKPSLpaqswkgvqdqpGLHLFGRPLSDYYAYRPVRE-QDAYSTLLSHIFHCRKESFITT 482
Cdd:PLN02640 457 VLRVQPDE----AIYLKINNKVPGL------------GMRLDRSDLNLLYRARYPREiPDAYERLLLDAIEGERRLFIRS 520
|
490 500 510
....*....|....*....|....*....|.
gi 157821675 483 ENLLASWVFWTPLLDSLSFE--VPRLYPGGA 511
Cdd:PLN02640 521 DELDAAWALFTPLLKELEEKkiIPELYPYGS 551
|
|
| PLN02333 |
PLN02333 |
glucose-6-phosphate 1-dehydrogenase |
31-511 |
1.51e-69 |
|
glucose-6-phosphate 1-dehydrogenase
Pssm-ID: 215191 [Multi-domain] Cd Length: 604 Bit Score: 240.65 E-value: 1.51e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 31 VSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHsFSFHGAALTapqqgqKLMDKAL-----ESLSCPKDlVPSRCDELKA 105
Cdd:PLN02333 118 VSITVVGASGDLAKKKIFPALFALYYEGCLPEH-FTIFGYARS------KMTDAELrnmvsKTLTCRID-KRENCGEKME 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 106 QFLQLSQYR--QLKTVEDYQTLNKDIETQvqqdglwEAGRV----FYFSVPPFAYADIARNINSSCRPHPGaWLRVVFEK 179
Cdd:PLN02333 190 EFLKRCFYHsgQYDSQEHFAELDKKLKEH-------EGGRVsnrlFYLSIPPNIFVDAVKCASSSASSVNG-WTRVIVEK 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 180 PFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFY 259
Cdd:PLN02333 262 PFGRDSESSAALTKSLKQYLEEDQIFRIDHYLGKELVENLSVLRFSNL-IFEPLWSRQYIRNVQFIFSEDFGTEGRGGYF 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 260 EEYGVIRDTLQNHLTEILTLVAMELPPNISSSaAVLQHKLQAFQALRGLQKSNAILGQYQAYS-GQVR-----QELQKPD 333
Cdd:PLN02333 341 DNYGIIRDIMQNHLLQILALFAMETPVSLDAE-DIRNEKVKVLRSMRPIQLEDVVIGQYKSHTkGGVTypaytDDKTVPK 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 334 GfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFK-------NRAYCTQGERhwvpersrcLPQQIVFY 406
Cdd:PLN02333 420 G--SLTPTFAAAALFIDNARWDGVPFLMKAGKALHTKSAEIRVQFRhvpgnlyNRNFGTDLDQ---------ATNELVIR 488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 407 IGHGElghpAILVSKNLFKPSLpaqswkGVQ-DQPGLHLfgrplsdYYAYRPVRE-QDAYSTLLSHIFHCRKESFITTEN 484
Cdd:PLN02333 489 VQPDE----AIYLKINNKVPGL------GMRlDRSNLNL-------LYAARYSKEiPDAYERLLLDAIEGERRLFIRSDE 551
|
490 500
....*....|....*....|....*....
gi 157821675 485 LLASWVFWTPLLDSLSFE--VPRLYPGGA 511
Cdd:PLN02333 552 LDAAWALFTPLLKELEEKkiIPEYYPYGS 580
|
|
| G6PD_C |
pfam02781 |
Glucose-6-phosphate dehydrogenase, C-terminal domain; |
233-518 |
1.13e-64 |
|
Glucose-6-phosphate dehydrogenase, C-terminal domain;
Pssm-ID: 460694 Cd Length: 295 Bit Score: 217.69 E-value: 1.13e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 233 LWNRHHVERVEIILKETVDAGGRASFYEEYGVIRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKS- 311
Cdd:pfam02781 13 LWNRNYIDHVQITVAETLGVEGRGGYYDQAGALRDMVQNHLLQLLALVAME-PPVSFDAEDIRDEKVKVLRSLRPITPEd 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 312 ---NAILGQYQA--YSGQV----RQELQKPDGfqSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNra 382
Cdd:pfam02781 92 vedNVVRGQYGAgwIGGEPvpgyREEEGVPPD--SRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEIRIQFKD-- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 383 yctqgerhwVP-----ERSRCLPQQIVFYIGHGElghpAILVSKNLFKpslpaqswkgvqdqPGLHLFGRPLS---DYYA 454
Cdd:pfam02781 168 ---------VPhnlfrDPGTLPPNELVIRIQPDE----GIYLKFNAKV--------------PGLGMRLRPVEldfSYSD 220
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157821675 455 YRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLSFEVPRLYPGG----AENDHLLD 518
Cdd:pfam02781 221 RFGERIPEAYERLLLDVMRGDQTLFVRSDEVEAAWRIVDPILEAWDEEKPPPYPAGswgpKAADELLA 288
|
|
| PRK12854 |
PRK12854 |
glucose-6-phosphate 1-dehydrogenase; Provisional |
33-510 |
2.54e-64 |
|
glucose-6-phosphate 1-dehydrogenase; Provisional
Pssm-ID: 237234 [Multi-domain] Cd Length: 484 Bit Score: 222.99 E-value: 2.54e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 33 IILLGATGDLAKKYLWQGLFQLYLDE--------AGKGHSfsfhgaALTAPQQGQKLMDKALESLSCPKDlvpsrcDELK 104
Cdd:PRK12854 14 FVLFGATGDLAKRKLLPGLFHLARAGllppdwriVGTGRG------DVSAEAFREHARDALDEFGARKLD------DGEW 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 105 AQFLQLSQYRQLK-TVEDYQTLnKDIETQVQQDGLWEAGRVFYFSVPPFAYADIARNInsscrphPGAWL----RVVFEK 179
Cdd:PRK12854 82 ARFAKRLRYVPGGfLSAGPGAL-AAAVAAARAELGGDARLVHYLAVPPSAFLDVTRAL-------GEAGLaegsRVVMEK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 180 PFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRkALDGLWNRHHVERVEIILKETVDAGGRASFY 259
Cdd:PRK12854 154 PFGTDLASAEALNAAVHEVFDESQIFRIDHFLGKEAAQNILAFRFANG-LFEPIWNREFIDHVQIDVPETLGVDTRAAFY 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 260 EEYGVIRDTLQNHLTEILTLVAMElPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYsgqvRQElqkpDGF--QS 337
Cdd:PRK12854 233 DATGAYRDMVVTHLFQVLAFVAME-PPTALEPDAISEEKNKVFRSMRPLDPAEVVRGQYSGY----RDE----PGVapDS 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 338 LTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNrayctqgerhwvPERSrclpqqiVFYIGHGELGHPAI 417
Cdd:PRK12854 304 TTETFVALKVWIDNWRWAGVPFYLRTGKRMAEGQRIISIAFRE------------PPYS-------MFPAGSVGAQGPDH 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 418 LvSKNLFKPSLPAQSWKGVQDQPGLHLfgRPLSDYYAYRPVREQ----DAYSTLLSHIFHCRKESFITTENLLASWVFWT 493
Cdd:PRK12854 365 L-TFDLADNSKVSLSFYGKRPGPGMRL--DKLSLQFSLKDTGPKgdvlEAYERLILDALRGDHTLFTTADGIESLWEVSQ 441
|
490
....*....|....*..
gi 157821675 494 PLLDSLSfeVPRLYPGG 510
Cdd:PRK12854 442 PLLEDPP--PVKPYAPG 456
|
|
| NagB |
COG0363 |
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ... |
566-794 |
4.14e-55 |
|
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway
Pssm-ID: 440132 [Multi-domain] Cd Length: 248 Bit Score: 189.99 E-value: 4.14e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 566 PEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYS--FPWAYTHLWLVDERC-VPLSDPDSNFQGL 642
Cdd:COG0363 10 AEELAAAAAERAAERIAEAIAEKGRAVLGLAGGSTPLGLYEELARLHKEggLDWSRVHVFNLDEYVgLPPDHPQSNRRFM 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 643 QAHLLQHVRVPYYNIHPMPVHLhqrlcAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPRGLDGDQLV 722
Cdd:COG0363 90 REALLDHVDIPPENIHIPDGEA-----EDPEAAAARYEALIAEA---GGIDLQLLGIGEDGHIAFNFPGSPFLSETDRVV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 723 VLTESPFR------------PHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRV--GHEPKKWPISGVVPLSgQLVW 788
Cdd:COG0363 162 TLDESTRQanarffgsipkvPPQAITLGIPTIMKAREILLLATGENKAEA---VAAAleGPVTEEVPASILQGHP-NVTW 237
|
....*.
gi 157821675 789 YMDYEA 794
Cdd:COG0363 238 FLDEAA 243
|
|
| G6PD_N |
pfam00479 |
Glucose-6-phosphate dehydrogenase, NAD binding domain; |
34-216 |
2.93e-41 |
|
Glucose-6-phosphate dehydrogenase, NAD binding domain;
Pssm-ID: 459827 [Multi-domain] Cd Length: 178 Bit Score: 149.11 E-value: 2.93e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 34 ILLGATGDLAKKYLWQGLFQLYLDeagkGH---SFSFHGAALTaPQQGQKLMDKALESLSCPKDlvpsRCDELKAQFLQL 110
Cdd:pfam00479 1 VIFGATGDLAKRKLFPALYNLYRD----GLlpeGFRIIGVARR-DLSDEEFRERVREALKEFKE----LDEEKWDRFLER 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 111 SQYRQ--LKTVEDYQTLNKDIEtqvQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSA 188
Cdd:pfam00479 72 LHYVSgdFDDPESYEKLKERLE---EHEDETRGNRLFYLAVPPSLFGPIAENLGRAGLSEEGGWRRVVIEKPFGHDLESA 148
|
170 180
....*....|....*....|....*...
gi 157821675 189 QQLASELGSFFQEEEMYRVDHYLGKQAV 216
Cdd:pfam00479 149 RELNDQLAKVFKEEQIYRIDHYLGKETV 176
|
|
| PLN02360 |
PLN02360 |
probable 6-phosphogluconolactonase |
567-794 |
3.17e-30 |
|
probable 6-phosphogluconolactonase
Pssm-ID: 166001 [Multi-domain] Cd Length: 268 Bit Score: 120.35 E-value: 3.17e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 567 EELISKLANDIEAAAVQAVRRFGKFHLALSGGSSpIALFQQLATGHY--SFPWAYTHLWLVDERCVPLSDPDSNFQGLQA 644
Cdd:PLN02360 20 DELSTDLAEYIAELSEASVKERGVFAIALSGGSL-ISFMGKLCEAPYnkTVDWAKWYIFWADERVVAKNHADSNYKLAKD 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 645 HLLQHVRVPYYNIHPmpvhLHQRLCAEEdqGAQTYASEISALVANSS-----------FDLVLLGMGTDGHTASLFPQSP 713
Cdd:PLN02360 99 GLLSKVPVVPSHVYS----INDTVTAEE--AATDYEFAIRQLVKTRTigvsdisdcpkFDLILLGMGSDGHVASLFPNHP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 714 R-GLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTL-VSRVGHEP--KKWPISGVVPLSGQLVWY 789
Cdd:PLN02360 173 AlEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKANAVHLaIDDVTEGPdaPSLPARMVQPTKGKLVWF 252
|
....*
gi 157821675 790 MDYEA 794
Cdd:PLN02360 253 LDKPA 257
|
|
| GlcN6P_deaminase |
cd01399 |
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ... |
578-777 |
2.02e-13 |
|
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.
Pssm-ID: 238693 [Multi-domain] Cd Length: 232 Bit Score: 70.59 E-value: 2.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 578 EAAA---VQAVRRFGKFHLALSGGSSPIALFQQLATGHYS--FPWAYTHLWLVDERcVPLS--DPDSNFQGLQAHLLQHV 650
Cdd:cd01399 5 EAAAeliAELIREKPPAVLGLATGSTPLGVYEELIELHKEggLSFSNVTTFNLDEY-VGLPpdHPQSYHYFMRENLFDHI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 651 RVPYYNIHPMPVhlhqrLCAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTAslFPQSPRGLDGD-QLVVLTES-- 727
Cdd:cd01399 84 DIKPENIHIPDG-----NAADLEAECRRYEALIAEA---GGIDLQLLGIGENGHIG--FNEPGSSLDSRtRVVTLDEStr 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157821675 728 -----PFR-----PHQRMSLSLPLINRAKKVAVLVMGRTKREIttlVSRVGHEP--KKWPIS 777
Cdd:cd01399 154 qanarFFDgdedvPTQAITMGIGTIMKAKEILLLATGEGKAEA---VKKALEGPvtEECPAS 212
|
|
| SugarP_isomerase |
cd00458 |
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate ... |
590-705 |
6.40e-08 |
|
SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium, the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate. 6PGL converts 6-phosphoglucono-1,5-lactone to 6-phosphogluconate, the second step of the oxidative phase of the pentose phosphate pathway.
Pssm-ID: 238258 Cd Length: 169 Bit Score: 53.13 E-value: 6.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 590 KFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLhqrlc 669
Cdd:cd00458 21 DMVIGLGTGSTPAYFYKLLGEKLKRGEISDIVGFPTDERYVPLDSDQSNFRQAKLLAFEHDIIPASNVHYVDTSL----- 95
|
90 100 110
....*....|....*....|....*....|....*.
gi 157821675 670 AEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHT 705
Cdd:cd00458 96 PIEKACEKYEREILDQV---DAIDLAVDGAGYRAGT 128
|
|
| PTZ00285 |
PTZ00285 |
glucosamine-6-phosphate isomerase; Provisional |
591-777 |
2.83e-07 |
|
glucosamine-6-phosphate isomerase; Provisional
Pssm-ID: 140308 Cd Length: 253 Bit Score: 52.45 E-value: 2.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 591 FHLALSGGSSPIALFQQLATGH----YSFPWAYThlWLVDERC-VPLSDPDSNFQGLQAHLLQHVrvpyyNIHPMPVHLH 665
Cdd:PTZ00285 35 FVLGLPTGSTPLPTYQELIRAYregrVSFSNVVT--FNMDEYVgLPRDHPQSYHYFMKENFFDHV-----DIKEENRHIL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 666 QRLCAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPRGlDGDQLVVLTESPFR-------------PH 732
Cdd:PTZ00285 108 NGTAPDLEEECRRYEEKIRAV---GGIDLFLAGIGTDGHIAFNEPGSSLD-SRTRVKSLNQETIDanarffgndiskvPT 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 157821675 733 QRMSLSLPLINRAKKVAVLVMGRTKREITT--LVSRVGHepkKWPIS 777
Cdd:PTZ00285 184 MALTVGIRTIMEAREVLLLATGASKAIAVArcVEGGVTH---MCPAS 227
|
|
| PRK02122 |
PRK02122 |
glucosamine-6-phosphate deaminase-like protein; Validated |
566-760 |
8.45e-06 |
|
glucosamine-6-phosphate deaminase-like protein; Validated
Pssm-ID: 235005 [Multi-domain] Cd Length: 652 Bit Score: 49.26 E-value: 8.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 566 PEELISKLANDIeAAAVQAVRRFGKFH-LALSGGSSPIALFQQLATGH----YSFPWAYThlWLVDERcVPLS--DPDSN 638
Cdd:PRK02122 36 SEEASRAVAQEI-ATLIRERQAEGKPCvLGLATGSSPIGVYAELIRMHreegLSFKNVIT--FNLDEY-YPMQpdSLQSY 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 639 FQGLQAHLLQHVRVPYYNIHPMPVHLHQrlcAEEDQGAQTYASEISALvanSSFDLVLLGMGTDGHTASLFPQSPRGlDG 718
Cdd:PRK02122 112 HRFMKENLFDHVDIPPENIHIPDGTIPK---EEIDEYCRDYEEKIEAA---GGIDFQLLGIGRTGHIGFNEPGSGRN-SR 184
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 157821675 719 DQLVVLTESPFR------------PHQRMSLSLPLINRAKKVAVLVMGRTKREI 760
Cdd:PRK02122 185 TRLVTLDHITRRdaasdffgeenvPRKAITMGVGTILKARRIVLLAWGEHKAPI 238
|
|
| nagB |
PRK00443 |
glucosamine-6-phosphate deaminase; Provisional |
574-777 |
2.66e-05 |
|
glucosamine-6-phosphate deaminase; Provisional
Pssm-ID: 179028 [Multi-domain] Cd Length: 261 Bit Score: 46.75 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 574 ANDIEAAAVQAVRRFGK-FHLALSGGSSPIALFQQLATGHYS--FPWAYTHLWLVDE-RCVPLSDPDS--NFqgLQAHLL 647
Cdd:PRK00443 17 ARHIANRINAFLPTKERpFVLGLATGSSPLETYKALIELHKAgkVDFSRVTTFNLDEyVGLPADHPESyrYF--MRENFF 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 648 QHVrvpyyNIHPMPVHLHQRLCAEEDQGAQTYASEIsalVANSSFDLVLLGMGTDGHTAslF--PQSPrgLDGDQLVV-L 724
Cdd:PRK00443 95 DHV-----DIPPENINLLNGNAPDPEAECRRYEEKI---KSAGGIDLQILGIGENGHIA--FnePGSS--FASRTRIKtL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157821675 725 TESPFR-------------PHQRMSLSLPLINRAKKVAVLVMGRTKREIT--TLVSRVGHEpkkWPIS 777
Cdd:PRK00443 163 TEDTRIansrffdgdieqvPKYALTVGVGTILDAKEIMLLAPGHNKAEAVkaAVEGPVNHM---WPAS 227
|
|
| PRK12358 |
PRK12358 |
glucosamine-6-phosphate deaminase; |
590-704 |
2.71e-03 |
|
glucosamine-6-phosphate deaminase;
Pssm-ID: 183470 Cd Length: 239 Bit Score: 40.12 E-value: 2.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157821675 590 KFHLALSGGSSPIALFQQLATGHYSFPW-AYTHLWLVDErcVPLSDPDS---NFQGLQAHLLQHVRVPYYNIHPMPVhlh 665
Cdd:PRK12358 29 RVNLAITAGSTPKGMYEYLITLVKGKAWyDNVHYYNFDE--IPFRGKEGegvTITNLRNLFFTPAGIKEENIHKLTI--- 103
|
90 100 110
....*....|....*....|....*....|....*....
gi 157821675 666 qrlcaeedqgaQTYASEISALVANSSFDLVLLGMGTDGH 704
Cdd:PRK12358 104 -----------DNYREHDQKLARDGGLDLVVLGLGADGH 131
|
|
|