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Conserved domains on  [gi|157823551|ref|NP_001099540|]
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microtubule-associated protein 1S [Rattus norvegicus]

Protein Classification

ComEC/Rec2 family competence protein( domain architecture ID 707784)

ComEC/Rec2 family competence protein similar to Bacillus subtilis ComE operon protein 3, which is required for DNA internalization; the comE operon is required for the binding and uptake of transforming DNA

CATH:  3.60.15.10
Gene Ontology:  GO:0016020|GO:0030420
PubMed:  7968523|8901420
SCOP:  3001057

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
457-860 1.08e-03

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  457 PSRANSQDSLASRDSTRKEPVRGTVGATSRSAVRREPALATRDQKKDTKPGPTRstVRDVRRSGPGVVTTKPRVSQNGPR 536
Cdd:PHA03247 2607 DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGR--VSRPRRARRLGRAAQASSPPQRPR 2684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  537 APVPaappaapapefPGEAENIVESERPPAPSPTlsPAQSPPPTAPGNsperlslsplrpePAPDASPSATTPTLTTPSL 616
Cdd:PHA03247 2685 RRAA-----------RPTVGSLTSLADPPPPPPT--PEPAPHALVSAT-------------PLPPGPAAARQASPALPAA 2738
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  617 PAELGSPHSTEVDESLSVSFEQVLPAGDAGLSLPLRLA----RRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSAR 692
Cdd:PHA03247 2739 PAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAagppRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  693 SQERPPETPPTSVSESLPTLSDSDPVPVADSDDDAGSESAARD------PLPTPRVPPPLPDAPGICMVDPEALPPRARQ 766
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  767 PLSTANSSRGRKAPARPSSASAAPRAATVAAKTKGPVGDRSR-PLSARSEPADKPGRVPLTRKPSVPKTVPKMASATRNS 845
Cdd:PHA03247 2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQpPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFR 2978
                         410
                  ....*....|....*
gi 157823551  846 SGPSSRPAPLAAGSP 860
Cdd:PHA03247 2979 VPQPAPSREAPASST 2993
ComEC super family cl28169
DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily ...
242-300 7.72e-03

DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily [Intracellular trafficking, secretion, and vesicular transport];


The actual alignment was detected with superfamily member COG2333:

Pssm-ID: 441904 [Multi-domain]  Cd Length: 253  Bit Score: 39.07  E-value: 7.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157823551 242 GLGDAAFF-AVNGFTVLVNGGSNPKSSFWKLV-------RHLDRVDAVLVTHAGADSLPGLNSLLRR 300
Cdd:COG2333    9 GQGDAILIrTPDGKTILIDTGPRPSFDAGERVvlpylraLGIRRLDLLVLTHPDADHIGGLAAVLEA 75
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
457-860 1.08e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  457 PSRANSQDSLASRDSTRKEPVRGTVGATSRSAVRREPALATRDQKKDTKPGPTRstVRDVRRSGPGVVTTKPRVSQNGPR 536
Cdd:PHA03247 2607 DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGR--VSRPRRARRLGRAAQASSPPQRPR 2684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  537 APVPaappaapapefPGEAENIVESERPPAPSPTlsPAQSPPPTAPGNsperlslsplrpePAPDASPSATTPTLTTPSL 616
Cdd:PHA03247 2685 RRAA-----------RPTVGSLTSLADPPPPPPT--PEPAPHALVSAT-------------PLPPGPAAARQASPALPAA 2738
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  617 PAELGSPHSTEVDESLSVSFEQVLPAGDAGLSLPLRLA----RRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSAR 692
Cdd:PHA03247 2739 PAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAagppRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  693 SQERPPETPPTSVSESLPTLSDSDPVPVADSDDDAGSESAARD------PLPTPRVPPPLPDAPGICMVDPEALPPRARQ 766
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  767 PLSTANSSRGRKAPARPSSASAAPRAATVAAKTKGPVGDRSR-PLSARSEPADKPGRVPLTRKPSVPKTVPKMASATRNS 845
Cdd:PHA03247 2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQpPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFR 2978
                         410
                  ....*....|....*
gi 157823551  846 SGPSSRPAPLAAGSP 860
Cdd:PHA03247 2979 VPQPAPSREAPASST 2993
ComEC COG2333
DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily ...
242-300 7.72e-03

DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441904 [Multi-domain]  Cd Length: 253  Bit Score: 39.07  E-value: 7.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157823551 242 GLGDAAFF-AVNGFTVLVNGGSNPKSSFWKLV-------RHLDRVDAVLVTHAGADSLPGLNSLLRR 300
Cdd:COG2333    9 GQGDAILIrTPDGKTILIDTGPRPSFDAGERVvlpylraLGIRRLDLLVLTHPDADHIGGLAAVLEA 75
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
457-860 1.08e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  457 PSRANSQDSLASRDSTRKEPVRGTVGATSRSAVRREPALATRDQKKDTKPGPTRstVRDVRRSGPGVVTTKPRVSQNGPR 536
Cdd:PHA03247 2607 DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGR--VSRPRRARRLGRAAQASSPPQRPR 2684
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  537 APVPaappaapapefPGEAENIVESERPPAPSPTlsPAQSPPPTAPGNsperlslsplrpePAPDASPSATTPTLTTPSL 616
Cdd:PHA03247 2685 RRAA-----------RPTVGSLTSLADPPPPPPT--PEPAPHALVSAT-------------PLPPGPAAARQASPALPAA 2738
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  617 PAELGSPHSTEVDESLSVSFEQVLPAGDAGLSLPLRLA----RRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSAR 692
Cdd:PHA03247 2739 PAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAagppRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  693 SQERPPETPPTSVSESLPTLSDSDPVPVADSDDDAGSESAARD------PLPTPRVPPPLPDAPGICMVDPEALPPRARQ 766
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrrrppSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  767 PLSTANSSRGRKAPARPSSASAAPRAATVAAKTKGPVGDRSR-PLSARSEPADKPGRVPLTRKPSVPKTVPKMASATRNS 845
Cdd:PHA03247 2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQpPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFR 2978
                         410
                  ....*....|....*
gi 157823551  846 SGPSSRPAPLAAGSP 860
Cdd:PHA03247 2979 VPQPAPSREAPASST 2993
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
455-860 1.68e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.47  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  455 EVPSRANSQDSLASRDSTRKEPVRGTVGATSRSAVRREPALATRDQKKDTKPGPTRSTVRDVRRSGPGVVTTKPRVSQNG 534
Cdd:PHA03307   66 EPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPG 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  535 PRAPVPAappaapapEFPGEAENIVESERPPAPSPTLsPAQSPPPTAPGNSPERLSLSPLRPEPAPDASPSATTPTLTTP 614
Cdd:PHA03307  146 PPPAASP--------PAAGASPAAVASDAASSRQAAL-PLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISAS 216
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  615 SLPAELGSPHSTEVDESLSVSFEQVLPAGDAGLSLPLRLARRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSARSQ 694
Cdd:PHA03307  217 ASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSP 296
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  695 ERPPETPPTSVSESLPTLSDSDpVPVADSDDDAGSESaardplptprvppplPDAPGICMVDPEALPPRARQPLSTANSS 774
Cdd:PHA03307  297 SPSPSSPGSGPAPSSPRASSSS-SSSRESSSSSTSSS---------------SESSRGAAVSPGPSPSRSPSPSRPPPPA 360
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157823551  775 RGRKAPARPSSASAAPRAATVAAKtkgPVGDRSRPLSARSE-PADKPGRVPLTRKPSVPktvpkMASATRNSSGPSSRPA 853
Cdd:PHA03307  361 DPSSPRKRPRPSRAPSSPAASAGR---PTRRRARAAVAGRArRRDATGRFPAGRPRPSP-----LDAGAASGAFYARYPL 432

                  ....*..
gi 157823551  854 PLAAGSP 860
Cdd:PHA03307  433 LTPSGEP 439
ComEC COG2333
DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily ...
242-300 7.72e-03

DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441904 [Multi-domain]  Cd Length: 253  Bit Score: 39.07  E-value: 7.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 157823551 242 GLGDAAFF-AVNGFTVLVNGGSNPKSSFWKLV-------RHLDRVDAVLVTHAGADSLPGLNSLLRR 300
Cdd:COG2333    9 GQGDAILIrTPDGKTILIDTGPRPSFDAGERVvlpylraLGIRRLDLLVLTHPDADHIGGLAAVLEA 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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