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Conserved domains on  [gi|161078585|ref|NP_001097904|]
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HDC15381 [Drosophila melanogaster]

Protein Classification

DM4/DM12 family protein( domain architecture ID 10545161)

DM4/DM12 family protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
123-203 5.26e-27

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


:

Pssm-ID: 462285  Cd Length: 86  Bit Score: 98.91  E-value: 5.26e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078585  123 RVWLYDVVETGLERLGdRNAGACLLKCICEISQRPFMH-NSIFGEILNAVLVPSLDNVPE-----KYLHARNAGKAGANC 196
Cdd:pfam07841   1 RRDLYRKLEELLERYG-FDGRACLLRAICEAAQRPLPEnNGLLGELLHILFTPSSSEDEElddddEYLEAERAGRSGADC 79

                  ....*..
gi 161078585  197 RKTYSDC 203
Cdd:pfam07841  80 AQLYPEC 86
 
Name Accession Description Interval E-value
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
123-203 5.26e-27

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


Pssm-ID: 462285  Cd Length: 86  Bit Score: 98.91  E-value: 5.26e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078585  123 RVWLYDVVETGLERLGdRNAGACLLKCICEISQRPFMH-NSIFGEILNAVLVPSLDNVPE-----KYLHARNAGKAGANC 196
Cdd:pfam07841   1 RRDLYRKLEELLERYG-FDGRACLLRAICEAAQRPLPEnNGLLGELLHILFTPSSSEDEElddddEYLEAERAGRSGADC 79

                  ....*..
gi 161078585  197 RKTYSDC 203
Cdd:pfam07841  80 AQLYPEC 86
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
120-208 1.12e-24

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


Pssm-ID: 214785  Cd Length: 95  Bit Score: 93.16  E-value: 1.12e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078585   120 DETRVWLYDVVETGLERLGdRNAGACLLKCICEISQRPFMHNSIFGEILNAVLVPS---LDNVPEKYLHARNAGKAGANC 196
Cdd:smart00718   3 DRSRRLLYEALENLLDQLG-FNGRACLLRAICESAQKLDDHRGLLGELLRIVLTPPdelEEVLDPDYREAYRAGRAGGDC 81
                           90
                   ....*....|..
gi 161078585   197 RKTYSDCSKAFW 208
Cdd:smart00718  82 DRLYSHCPLSLL 93
 
Name Accession Description Interval E-value
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
123-203 5.26e-27

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


Pssm-ID: 462285  Cd Length: 86  Bit Score: 98.91  E-value: 5.26e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078585  123 RVWLYDVVETGLERLGdRNAGACLLKCICEISQRPFMH-NSIFGEILNAVLVPSLDNVPE-----KYLHARNAGKAGANC 196
Cdd:pfam07841   1 RRDLYRKLEELLERYG-FDGRACLLRAICEAAQRPLPEnNGLLGELLHILFTPSSSEDEElddddEYLEAERAGRSGADC 79

                  ....*..
gi 161078585  197 RKTYSDC 203
Cdd:pfam07841  80 AQLYPEC 86
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
120-208 1.12e-24

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


Pssm-ID: 214785  Cd Length: 95  Bit Score: 93.16  E-value: 1.12e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078585   120 DETRVWLYDVVETGLERLGdRNAGACLLKCICEISQRPFMHNSIFGEILNAVLVPS---LDNVPEKYLHARNAGKAGANC 196
Cdd:smart00718   3 DRSRRLLYEALENLLDQLG-FNGRACLLRAICESAQKLDDHRGLLGELLRIVLTPPdelEEVLDPDYREAYRAGRAGGDC 81
                           90
                   ....*....|..
gi 161078585   197 RKTYSDCSKAFW 208
Cdd:smart00718  82 DRLYSHCPLSLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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