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Conserved domains on  [gi|161078050|ref|NP_001097689|]
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diphthamide biosynthesis 4, isoform B [Drosophila melanogaster]

Protein Classification

diphthamide biosynthesis protein 4( domain architecture ID 10446362)

diphthamide biosynthesis protein 4 (DPH4) is a J domain-containing CSL-type zinc finger protein that is required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-72 2.42e-21

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 82.52  E-value: 2.42e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050    3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDK-------NPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
zf-CSL pfam05207
CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which ...
 138-179 4.48e-09

CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which chelate zinc. This domain is often found associated with a pfam00226 domain. This domain is named after the conserved motif of the final cysteine.


:

Pssm-ID: 398744  Cd Length: 55  Bit Score: 50.32  E-value: 4.48e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 161078050  138 SYAYDCRCGGQYLFdgPADDDESPEVIVECNECSLVIIVKQA 179
Cdd:pfam05207  16 SYYYPCRCGDEFEI--TEEDLEEGEVVVQCPSCSLWIKVIYD 55
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-72 2.42e-21

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 82.52  E-value: 2.42e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050    3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDK-------NPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-78 3.95e-18

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 75.14  E-value: 3.95e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161078050   1 MPDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqLDDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYDAELLQS 78
Cdd:COG2214    4 LKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDR---GGELKALAEEL---FQRLNEAYEVLSDPERRAEYDRELGQS 75
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-64 1.29e-16

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 69.88  E-value: 1.29e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKD 64
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDK-------NPDDPEAEEKFKEINEAYEVLSD 55
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-65 7.50e-15

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 65.72  E-value: 7.50e-15
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 161078050     2 PDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSD-FNAINAAWNTLKDP 65
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDK-------NPGDKEEAEEkFKEINEAYEVLSDP 58
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1-72 2.19e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 69.92  E-value: 2.19e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161078050   1 MPDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14292   1 MMDYYELLGVSRTASADEIKSAYRKLALKYHPDR-----NKEKGAAEK---FAQINEAYAVLSDAEKRAHYD 64
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-72 3.44e-13

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 66.47  E-value: 3.44e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050    3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDR-----NKDKEAEEK---FKEINEAYEVLSDPEKRAQYD 62
zf-CSL pfam05207
CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which ...
 138-179 4.48e-09

CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which chelate zinc. This domain is often found associated with a pfam00226 domain. This domain is named after the conserved motif of the final cysteine.


Pssm-ID: 398744  Cd Length: 55  Bit Score: 50.32  E-value: 4.48e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 161078050  138 SYAYDCRCGGQYLFdgPADDDESPEVIVECNECSLVIIVKQA 179
Cdd:pfam05207  16 SYYYPCRCGDEFEI--TEEDLEEGEVVVQCPSCSLWIKVIYD 55
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-72 4.10e-06

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 45.97  E-value: 4.10e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:NF037946   6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDR-----NKAPDAAEI---FAEINEAYEVLSNPEKRANYD 67
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-72 2.42e-21

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 82.52  E-value: 2.42e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050    3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDK-------NPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-78 3.95e-18

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 75.14  E-value: 3.95e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161078050   1 MPDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqLDDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYDAELLQS 78
Cdd:COG2214    4 LKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDR---GGELKALAEEL---FQRLNEAYEVLSDPERRAEYDRELGQS 75
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-73 9.24e-18

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 75.51  E-value: 9.24e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYDA 73
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDR-------NPGDPEAEEKFKEINEAYEVLSDPEKRAAYDR 64
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-64 1.29e-16

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 69.88  E-value: 1.29e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKD 64
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDK-------NPDDPEAEEKFKEINEAYEVLSD 55
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-65 7.50e-15

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 65.72  E-value: 7.50e-15
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 161078050     2 PDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSD-FNAINAAWNTLKDP 65
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDK-------NPGDKEEAEEkFKEINEAYEVLSDP 58
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1-72 2.19e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 69.92  E-value: 2.19e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161078050   1 MPDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14292   1 MMDYYELLGVSRTASADEIKSAYRKLALKYHPDR-----NKEKGAAEK---FAQINEAYAVLSDAEKRAHYD 64
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-72 1.78e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 67.09  E-value: 1.78e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDR-------NPGDKEAEEKFKEIKEAYEVLSDPQKRAAYD 67
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 3-72 3.44e-13

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 66.47  E-value: 3.44e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050    3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDR-----NKDKEAEEK---FKEINEAYEVLSDPEKRAQYD 62
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 3-72 8.94e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 65.18  E-value: 8.94e-13
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14291   4 DYYEILGVSRNATQEEIKKAYRRLARKYHPDF-----NKNPEAEEK---FKEINEAYQVLSDPEKRKLYD 65
PRK14279 PRK14279
molecular chaperone DnaJ;
3-72 1.85e-12

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 64.37  E-value: 1.85e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14279  10 DFYKELGVSSDASAEEIKKAYRKLARELHPDA-------NPGDPAAEERFKAVSEAHDVLSDPAKRKEYD 72
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 3-72 2.75e-12

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 64.05  E-value: 2.75e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14277   6 DYYEILGVDRNATEEEIKKAYRRLAKKYHPDL-------NPGDKEAEQKFKEINEAYEILSDPQKRAQYD 68
PRK14295 PRK14295
molecular chaperone DnaJ;
3-72 5.70e-12

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 62.94  E-value: 5.70e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14295  10 DYYKVLGVPKDATEAEIKKAYRKLAREYHPDA-------NKGDAKAEERFKEISEAYDVLSDEKKRKEYD 72
PRK14289 PRK14289
molecular chaperone DnaJ;
3-72 1.02e-11

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 62.16  E-value: 1.02e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14289   6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDK-------NPGDKEAEEKFKEAAEAYDVLSDPDKRSRYD 68
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 3-72 1.21e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 61.49  E-value: 1.21e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14299   5 DYYAILGVPKNASQDEIKKAFKKLARKYHPDV-----NKSPGAEEK---FKEINEAYTVLSDPEKRRIYD 66
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
1-65 2.19e-11

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 56.73  E-value: 2.19e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161078050   1 MPDFYELLNVPSTASFDEIKCSYKQLILQCHPDKLRQlddpnPGSEA------QNSDfnAINAAWNTLKDP 65
Cdd:COG1076    3 LDDAFELLGLPPDADDAELKRAYRKLQREHHPDRLAA-----GLPEEeqrlalQKAA--AINEAYETLKDP 66
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 3-72 3.22e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 60.63  E-value: 3.22e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDK-------NPGDAEAEKRFKEVSEAYEVLSDAQKRESYD 64
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 3-72 4.39e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 60.59  E-value: 4.39e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14281   4 DYYEVLGVSRSADKDEIKKAYRKLALKYHPDK-------NPDNKEAEEHFKEVNEAYEVLSNDDKRRRYD 66
PRK14297 PRK14297
molecular chaperone DnaJ;
3-72 4.44e-11

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 60.57  E-value: 4.44e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14297   5 DYYEVLGLEKGASDDEIKKAFRKLAIKYHPDK-------NKGNKEAEEKFKEINEAYQVLSDPQKKAQYD 67
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 3-72 6.89e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 59.78  E-value: 6.89e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14294   5 DYYEILGVTRDASEEEIKKSYRKLAMKYHPDR-------NPGDKEAEELFKEAAEAYEVLSDPKKRGIYD 67
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 3-72 9.32e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 59.42  E-value: 9.32e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQNSdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14282   5 DYYEILGVSRNATQEEIKRAYKRLVKEWHPDR-----HPENRKEAEQK-FKEIQEAYEVLSDPQKRAMYD 68
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 3-72 1.29e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 59.09  E-value: 1.29e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14298   6 DYYEILGLSKDASVEDIKKAYRKLAMKYHPDK-----NKEPDAEEK---FKEISEAYAVLSDAEKRAQYD 67
PRK14293 PRK14293
molecular chaperone DnaJ;
1-72 6.97e-10

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 56.92  E-value: 6.97e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161078050   1 MPDFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14293   2 AADYYEILGVSRDADKDELKRAYRRLARKYHPDV-----NKEPGAEDR---FKEINRAYEVLSDPETRARYD 65
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 3-72 8.26e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 56.67  E-value: 8.26e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14301   5 DYYEVLGVSRDASEDEIKKAYRKLALQYHPDR-------NPDNPEAEQKFKEAAEAYEVLRDAEKRARYD 67
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 4-72 8.99e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 56.54  E-value: 8.99e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161078050   4 FYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14286   6 YYDILGVSKSANDEEIKSAYRKLAIKYHPDK-------NKGNKESEEKFKEATEAYEILRDPKKRQAYD 67
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 3-72 2.17e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 55.40  E-value: 2.17e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14287   5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPDV-----NKAPDAEDK---FKEVKEAYDTLSDPQKKAHYD 66
zf-CSL pfam05207
CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which ...
 138-179 4.48e-09

CSL zinc finger; This is a zinc binding motif which contains four cysteine residues which chelate zinc. This domain is often found associated with a pfam00226 domain. This domain is named after the conserved motif of the final cysteine.


Pssm-ID: 398744  Cd Length: 55  Bit Score: 50.32  E-value: 4.48e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 161078050  138 SYAYDCRCGGQYLFdgPADDDESPEVIVECNECSLVIIVKQA 179
Cdd:pfam05207  16 SYYYPCRCGDEFEI--TEEDLEEGEVVVQCPSCSLWIKVIYD 55
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 3-72 8.76e-09

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 53.52  E-value: 8.76e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQnSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14278   4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDV-------NPDEEAQ-EKFKEISVAYEVLSDPEKRRIVD 65
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 3-72 4.27e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 51.55  E-value: 4.27e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDklrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14300   4 DYYQILGVSKTASQADLKKAYLKLAKQYHPD--------TTDAKDAEKKFKEINAAYDVLKDEQKRAAYD 65
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 3-72 4.51e-08

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 51.63  E-value: 4.51e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14276   5 EYYDRLGVSKDASQDEIKKAYRKLSKKYHPDI-----NKEPGAEEK---YKEVQEAYETLSDPQKRAAYD 66
PRK10266 PRK10266
curved DNA-binding protein;
3-85 8.01e-08

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 50.59  E-value: 8.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKLRQlddpnPGSEAQnsdFNAINAAWNTLKDPIRRKHYDaellqsKFRA 82
Cdd:PRK10266   5 DYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKE-----PDAEAR---FKEVAEAWEVLSDEQRRAEYD------QLWQ 70


                 ...
gi 161078050  83 HSN 85
Cdd:PRK10266  71 HRN 73
PRK14280 PRK14280
molecular chaperone DnaJ;
3-72 1.10e-07

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 50.49  E-value: 1.10e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpnpgSEAQNSD--FNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14280   5 DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDI----------NKEEGADekFKEISEAYEVLSDDQKRAQYD 66
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 3-72 1.48e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 49.93  E-value: 1.48e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSD-FNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14290   4 DYYKILGVDRNASQEDIKKAFRELAKKWHPDL-------HPGNKAEAEEkFKEISEAYEVLSDPQKRRQYD 67
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 3-72 2.05e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 49.60  E-value: 2.05e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14285   4 DYYEILGLSKGASKDEIKKAYRKIAIKYHPDK-------NKGNKEAESIFKEATEAYEVLIDDNKRAQYD 66
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 4-72 4.14e-07

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 49.05  E-value: 4.14e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161078050   4 FYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpnpGSEAQNsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PTZ00037  30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDK---------GGDPEK--FKEISRAYEVLSDPEKRKIYD 87
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 3-72 8.55e-07

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 48.02  E-value: 8.55e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14296   5 DYYEVLGVSKTASEQEIRQAYRKLAKQYHPDL-----NKSPDAHDK---MVEINEAADVLLDKDKRKQYD 66
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 3-72 3.47e-06

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 45.97  E-value: 3.47e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14283   6 DYYEVLGVDRNADKKEIKKAYRKLARKYHPDV-----SEEEGAEEK---FKEISEAYAVLSDDEKRQRYD 67
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-72 4.10e-06

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 45.97  E-value: 4.10e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqldDPNPGSEAQnsdFNAINAAWNTLKDPIRRKHYD 72
Cdd:NF037946   6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDR-----NKAPDAAEI---FAEINEAYEVLSNPEKRANYD 67
PRK14288 PRK14288
molecular chaperone DnaJ;
4-72 4.40e-05

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 42.75  E-value: 4.40e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161078050   4 FYELLNVPSTASFDEIKCSYKQLILQCHPDKlrqlddpNPGSEAQNSDFNAINAAWNTLKDPIRRKHYD 72
Cdd:PRK14288   5 YYEILEVEKHSNQETIKKSYRKLALKYHPDR-------NAGDKEAEEKFKLINEAYGVLSDEKKRALYD 66
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 5-33 5.21e-05

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 40.99  E-value: 5.21e-05
                         10        20
                 ....*....|....*....|....*....
gi 161078050   5 YELLNVPSTASFDEIKCSYKQLILQCHPD 33
Cdd:PTZ00100  68 YKILNISPTASKERIREAHKQLMLRNHPD 96
hscB TIGR00714
Fe-S protein assembly co-chaperone HscB; This model describes the small subunit, Hsc20 (20K ...
 23-108 2.99e-04

Fe-S protein assembly co-chaperone HscB; This model describes the small subunit, Hsc20 (20K heat shock cognate protein) of a pair of proteins Hsc66-Hsc20, related to the DnaK-DnaJ heat shock proteins, which also serve as molecular chaperones. Hsc20, unlike DnaJ, appears not to have chaperone activity on its own, but to act solely as a regulatory subunit for Hsc66 (i.e., to be a co-chaperone). The gene for Hsc20 in E. coli, hscB, is not induced by heat shock. [Protein fate, Protein folding and stabilization]


Pssm-ID: 211601 [Multi-domain]  Cd Length: 155  Bit Score: 39.48  E-value: 2.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161078050   23 YKQLILQCHPDKLRQLDDPNPGSEAQNSdfnaINAAWNTLKDPIRRKHYDAELLQSKFRAHSNIYATvVLSEMQRIQV-- 100
Cdd:TIGR00714  12 YRQLQAQYHPDASGMAQEQLAASQQSTT----LNQAYHTLKDPLRRAEYMLKLLNIDLTQEQTSERD-TAFPMELLKVrd 86

                          90
                  ....*....|.
gi 161078050  101 ---EIEEDDDE 108
Cdd:TIGR00714  87 eldEIEQMDDE 97
djlA PRK09430
co-chaperone DjlA;
3-35 1.93e-03

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 37.87  E-value: 1.93e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 161078050   3 DFYELLNVPSTASFDEIKCSYKQLILQCHPDKL 35
Cdd:PRK09430 201 DAYKVLGVSESDDDQEIKRAYRKLMSEHHPDKL 233
hscB PRK05014
co-chaperone HscB; Provisional
 3-71 4.96e-03

co-chaperone HscB; Provisional


Pssm-ID: 179914 [Multi-domain]  Cd Length: 171  Bit Score: 36.04  E-value: 4.96e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 161078050   3 DFYELLNVPstASFD----EIKCSYKQLILQCHPDKLRQlddpnpGSEAQNS---DFNA-INAAWNTLKDPIRRKHY 71
Cdd:PRK05014   2 DYFTLFGLP--ARYDidtqLLASRYQELQRQFHPDKFAN------ASERERLlavQQAAtINDAYQTLKHPLKRAEY 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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