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Conserved domains on  [gi|442630671|ref|NP_001097528|]
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uncharacterized protein Dmel_CG14826, isoform C [Drosophila melanogaster]

Protein Classification

DM4/DM12 family protein( domain architecture ID 10653853)

DM4/DM12 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
117-210 3.25e-32

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


:

Pssm-ID: 214785  Cd Length: 95  Bit Score: 112.42  E-value: 3.25e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630671   117 YADDARLLVYTALEEYMGRRNNDrsmGRQCLLRSICENAQ-IHHHIGVFSEIMDIVLSPG---KADLDNDYHDAYAAGRA 192
Cdd:smart00718   1 PHDRSRRLLYEALENLLDQLGFN---GRACLLRAICESAQkLDDHRGLLGELLRIVLTPPdelEEVLDPDYREAYRAGRA 77

                           90
                   ....*....|....*...
gi 442630671   193 GANCLGLYSACPRGHNFL 210
Cdd:smart00718  78 GGDCDRLYSHCPLSLLLL 95
 
Name Accession Description Interval E-value
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
117-210 3.25e-32

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


Pssm-ID: 214785  Cd Length: 95  Bit Score: 112.42  E-value: 3.25e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630671   117 YADDARLLVYTALEEYMGRRNNDrsmGRQCLLRSICENAQ-IHHHIGVFSEIMDIVLSPG---KADLDNDYHDAYAAGRA 192
Cdd:smart00718   1 PHDRSRRLLYEALENLLDQLGFN---GRACLLRAICESAQkLDDHRGLLGELLRIVLTPPdelEEVLDPDYREAYRAGRA 77

                           90
                   ....*....|....*...
gi 442630671   193 GANCLGLYSACPRGHNFL 210
Cdd:smart00718  78 GGDCDRLYSHCPLSLLLL 95
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
 122-203 7.58e-26

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


Pssm-ID: 462285  Cd Length: 86  Bit Score: 95.83  E-value: 7.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630671  122 RLLVYTALEEYMGRRNNDrsmGRQCLLRSICENAQI--HHHIGVFSEIMDIVLSPGKA-----DLDNDYHDAYAAGRAGA 194
Cdd:pfam07841   1 RRDLYRKLEELLERYGFD---GRACLLRAICEAAQRplPENNGLLGELLHILFTPSSSedeelDDDDEYLEAERAGRSGA 77


                  ....*....
gi 442630671  195 NCLGLYSAC 203
Cdd:pfam07841  78 DCAQLYPEC 86
 
Name Accession Description Interval E-value
DM4_12 smart00718
DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;
117-210 3.25e-32

DM4/DM12 family of domains in Drosophila melanogaster proteins of unknown function;


Pssm-ID: 214785  Cd Length: 95  Bit Score: 112.42  E-value: 3.25e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630671   117 YADDARLLVYTALEEYMGRRNNDrsmGRQCLLRSICENAQ-IHHHIGVFSEIMDIVLSPG---KADLDNDYHDAYAAGRA 192
Cdd:smart00718   1 PHDRSRRLLYEALENLLDQLGFN---GRACLLRAICESAQkLDDHRGLLGELLRIVLTPPdelEEVLDPDYREAYRAGRA 77

                           90
                   ....*....|....*...
gi 442630671   193 GANCLGLYSACPRGHNFL 210
Cdd:smart00718  78 GGDCDRLYSHCPLSLLLL 95
DM4_12 pfam07841
DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed ...
 122-203 7.58e-26

DM4/DM12 family; This family contains sequences derived from hypothetical proteins expressed by two insect species, D. melanogaster and A. gambiae. The region in question is approximately 115 amino acid residues long and contains four highly- conserved cysteine residues.


Pssm-ID: 462285  Cd Length: 86  Bit Score: 95.83  E-value: 7.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442630671  122 RLLVYTALEEYMGRRNNDrsmGRQCLLRSICENAQI--HHHIGVFSEIMDIVLSPGKA-----DLDNDYHDAYAAGRAGA 194
Cdd:pfam07841   1 RRDLYRKLEELLERYGFD---GRACLLRAICEAAQRplPENNGLLGELLHILFTPSSSedeelDDDDEYLEAERAGRSGA 77


                  ....*....
gi 442630671  195 NCLGLYSAC 203
Cdd:pfam07841  78 DCAQLYPEC 86
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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