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Conserved domains on  [gi|281371339|ref|NP_001094153|]
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kelch domain-containing protein 8A isoform 1 [Rattus norvegicus]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 19803719)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-337 6.15e-46

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 157.63  E-value: 6.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  58 QWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQlPVKVVEMYNIDEGKWKKRSVLREAAMGISVTA-KDYRVYAAGGMG 136
Cdd:COG3055    2 TWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGS-ASNSFEVYDPATNTWSELAPLPGPPRHHAAAVaQDGKLYVFGGFT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 137 LDLRPHNYLQH---YDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKR- 212
Cdd:COG3055   81 GANPSSTPLNDvyvYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRd 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 213 AFSSFVTLDNHLYSLGGlrqgrlyrqpkflrtmDVFDMEQGGWLKMERsffLKKRRADFVAGGLSGRVIVAGGLGNqptV 292
Cdd:COG3055  161 HLAAAVLPDGKILVIGG----------------RNGSGFSNTWTTLAP---LPTARAGHAAAVLGGKILVFGGESG---F 218

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 281371339 293 LETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQG 337
Cdd:COG3055  219 SDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETKP 263
NanM super family cl34543
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-101 2.38e-12

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG3055:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 66.33  E-value: 2.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  10 QWKRLAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMDCfEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGT 89
Cdd:COG3055  186 TWTTLAPLPTARAGHAAAVLGGKILVFGG--ESGFSDEV-EAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETK 262

                         90
                 ....*....|....*
gi 281371339  90 NQLP---VKVVEMYN 101
Cdd:COG3055  263 PGVRtplVTSAEVYD 277
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-337 6.15e-46

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 157.63  E-value: 6.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  58 QWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQlPVKVVEMYNIDEGKWKKRSVLREAAMGISVTA-KDYRVYAAGGMG 136
Cdd:COG3055    2 TWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGS-ASNSFEVYDPATNTWSELAPLPGPPRHHAAAVaQDGKLYVFGGFT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 137 LDLRPHNYLQH---YDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKR- 212
Cdd:COG3055   81 GANPSSTPLNDvyvYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRd 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 213 AFSSFVTLDNHLYSLGGlrqgrlyrqpkflrtmDVFDMEQGGWLKMERsffLKKRRADFVAGGLSGRVIVAGGLGNqptV 292
Cdd:COG3055  161 HLAAAVLPDGKILVIGG----------------RNGSGFSNTWTTLAP---LPTARAGHAAAVLGGKILVFGGESG---F 218

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 281371339 293 LETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQG 337
Cdd:COG3055  219 SDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETKP 263
PHA03098 PHA03098
kelch-like protein; Provisional
 5-209 7.75e-26

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 107.93  E-value: 7.75e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339   5 NVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVI 84
Cdd:PHA03098 317 DTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIY-NSISLNTVESWKPGESKWREEPPLIFPRYNPCVVNVNNLIYVI 395

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  85 GGVGTNQLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPH--NYLQHYDMLKDMWVSLAPMP 162
Cdd:PHA03098 396 GGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISYIDNIKvyNIVESYNPVTNKWTELSSLN 475

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 281371339 163 TPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIP 209
Cdd:PHA03098 476 FPRINASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTNTWTLFCKFP 522
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-101 2.38e-12

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 66.33  E-value: 2.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  10 QWKRLAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMDCfEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGT 89
Cdd:COG3055  186 TWTTLAPLPTARAGHAAAVLGGKILVFGG--ESGFSDEV-EAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETK 262

                         90
                 ....*....|....*
gi 281371339  90 NQLP---VKVVEMYN 101
Cdd:COG3055  263 PGVRtplVTSAEVYD 277
PHA03098 PHA03098
kelch-like protein; Provisional
 1-108 5.36e-11

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 63.63  E-value: 5.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339   1 MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCD--DNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALG 78
Cdd:PHA03098 408 VECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISyiDNIKVYNIVESYNPVTNKWTELSSLNFPRINASLCIFN 487

                         90       100       110
                 ....*....|....*....|....*....|
gi 281371339  79 KRIMVIGGVgTNQLPVKVVEMYNIDEGKWK 108
Cdd:PHA03098 488 NKIYVVGGD-KYEYYINEIEVYDDKTNTWT 516
Kelch smart00612
Kelch domain;
32-79 1.24e-10

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 56.03  E-value: 1.24e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 281371339    32 QVYAIGGCDdNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGK 79
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch smart00612
Kelch domain;
279-326 1.30e-09

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 53.33  E-value: 1.30e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 281371339   279 RVIVAGGLGNQpTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKN 326
Cdd:smart00612   1 KIYVVGGFDGG-QRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 20-66 1.39e-09

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 53.00  E-value: 1.39e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 281371339   20 RRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTSLPSLP 66
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFD-GNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch_6 pfam13964
Kelch motif;
278-316 3.08e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 43.86  E-value: 3.08e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 281371339  278 GRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPTPR 316
Cdd:pfam13964  12 GYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
58-337 6.15e-46

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 157.63  E-value: 6.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  58 QWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQlPVKVVEMYNIDEGKWKKRSVLREAAMGISVTA-KDYRVYAAGGMG 136
Cdd:COG3055    2 TWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGS-ASNSFEVYDPATNTWSELAPLPGPPRHHAAAVaQDGKLYVFGGFT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 137 LDLRPHNYLQH---YDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKR- 212
Cdd:COG3055   81 GANPSSTPLNDvyvYDPATNTWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQLAPLPTPRd 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 213 AFSSFVTLDNHLYSLGGlrqgrlyrqpkflrtmDVFDMEQGGWLKMERsffLKKRRADFVAGGLSGRVIVAGGLGNqptV 292
Cdd:COG3055  161 HLAAAVLPDGKILVIGG----------------RNGSGFSNTWTTLAP---LPTARAGHAAAVLGGKILVFGGESG---F 218

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 281371339 293 LETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQG 337
Cdd:COG3055  219 SDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETKP 263
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
5-229 2.17e-36

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 132.59  E-value: 2.17e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339   5 NVKDFQWKRLAPLP-SRRVYCSLLETGGQVYAIGGCD---DNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKR 80
Cdd:COG3055   44 DPATNTWSELAPLPgPPRHHAAAVAQDGKLYVFGGFTganPSSTPLNDVYVYDPATNTWTKLAPMPTPRGGATALLLDGK 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  81 IMVIGGVGTNQlPVKVVEMYNIDEGKWKKRSVLREAAMGIS-VTAKDYRVYAAGGmgldlrphnylQHYDMLKDMWVSLA 159
Cdd:COG3055  124 IYVVGGWDDGG-NVAWVEVYDPATGTWTQLAPLPTPRDHLAaAVLPDGKILVIGG-----------RNGSGFSNTWTTLA 191

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 160 PMPTPRYAATSFLRGSKIYVLGGrqSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGG 229
Cdd:COG3055  192 PLPTARAGHAAAVLGGKILVFGG--ESGFSDEVEAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGG 259
PHA03098 PHA03098
kelch-like protein; Provisional
 5-209 7.75e-26

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 107.93  E-value: 7.75e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339   5 NVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVI 84
Cdd:PHA03098 317 DTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIY-NSISLNTVESWKPGESKWREEPPLIFPRYNPCVVNVNNLIYVI 395

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  85 GGVGTNQLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPH--NYLQHYDMLKDMWVSLAPMP 162
Cdd:PHA03098 396 GGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISYIDNIKvyNIVESYNPVTNKWTELSSLN 475

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 281371339 163 TPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIP 209
Cdd:PHA03098 476 FPRINASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTNTWTLFCKFP 522
PHA03098 PHA03098
kelch-like protein; Provisional
 11-255 8.50e-25

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 104.85  E-value: 8.50e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  11 WKRLAPLPSRRVYCSLLETGgQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGTN 90
Cdd:PHA03098 276 INTIIDIHYVYCFGSVVLNN-VIYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNS 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  91 qLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATS 170
Cdd:PHA03098 355 -ISLNTVESWKPGESKWREEPPLIFPRYNPCVVNVNNLIYVIGGISKNDELLKTVECFSLNTNKWSKGSPLPISHYGGCA 433

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 171 FLRGSKIYVLGGRQSKYAVNAF---EVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGlrqgrlYRQPKFLRTMDV 247
Cdd:PHA03098 434 IYHDGKIYVIGGISYIDNIKVYnivESYNPVTNKWTELSSLNFPRINASLCIFNNKIYVVGG------DKYEYYINEIEV 507


                 ....*...
gi 281371339 248 FDMEQGGW 255
Cdd:PHA03098 508 YDDKTNTW 515
PHA03098 PHA03098
kelch-like protein; Provisional
 129-333 7.26e-19

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 87.52  E-value: 7.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 129 VYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNI 208
Cdd:PHA03098 297 IYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKWREEPPL 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 209 PCKRAFSSFVTLDNHLYSLGGlrqgrLYRQPKFLRTMDVFDMEQGGWLKMERsffLKKRRADFVAGGLSGRVIVAGGLG- 287
Cdd:PHA03098 377 IFPRYNPCVVNVNNLIYVIGG-----ISKNDELLKTVECFSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGISy 448

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 281371339 288 -NQPTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGG 333
Cdd:PHA03098 449 iDNIKVYNIVESYNPVTNKWTELSSLNFPRINASLCIFNNKIYVVGG 495
PLN02153 PLN02153
epithiospecifier protein
 128-333 3.17e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 69.63  E-value: 3.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 128 RVYAAGGmglDLRPHnylQHYDmlKDMWV--------SLAPM--PTPR---YAATSFLRGSKIYVLGGRQSKYAVNAFEV 194
Cdd:PLN02153  34 KLYSFGG---ELKPN---EHID--KDLYVfdfnthtwSIAPAngDVPRiscLGVRMVAVGTKLYIFGGRDEKREFSDFYS 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 195 FDIESRSWTKFPNI-----PCKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMER--SFFLKKR 267
Cdd:PLN02153 106 YDTVKNEWTFLTKLdeeggPEARTFHSMASDENHVYVFGGVSKGGLMKTPERFRTIEAYNIADGKWVQLPDpgENFEKRG 185

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 281371339 268 RADFVAggLSGRVIVAGGL-------GNQPTVLETAEAFHPEKNKW---EALPPMPTPRCACSSIVFKNCLLAVGG 333
Cdd:PLN02153 186 GAGFAV--VQGKIWVVYGFatsilpgGKSDYESNAVQFFDPASGKWtevETTGAKPSARSVFAHAVVGKYIIIFGG 259
PHA03098 PHA03098
kelch-like protein; Provisional
 143-335 3.68e-13

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 70.18  E-value: 3.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 143 NYLQHYDMLKDMWVSLAPmpTPRYAATSFLRGSKIYVLGGR-QSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLD 221
Cdd:PHA03098 265 NYITNYSPLSEINTIIDI--HYVYCFGSVVLNNVIYFIGGMnKNNLSVNSVVSYDTKTKSWNKVPELIYPRKNPGVTVFN 342

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 222 NHLYSLGGLRQGRLyrqpkfLRTMDVFDMEQGGWlkmERSFFLKKRRADFVAGGLSGRVIVAGGLGNQPTVLETAEAFHP 301
Cdd:PHA03098 343 NRIYVIGGIYNSIS------LNTVESWKPGESKW---REEPPLIFPRYNPCVVNVNNLIYVIGGISKNDELLKTVECFSL 413

                        170       180       190
                 ....*....|....*....|....*....|....
gi 281371339 302 EKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVS 335
Cdd:PHA03098 414 NTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGIS 447
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-101 2.38e-12

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 66.33  E-value: 2.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  10 QWKRLAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMDCfEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGT 89
Cdd:COG3055  186 TWTTLAPLPTARAGHAAAVLGGKILVFGG--ESGFSDEV-EAYDPATNTWTALGELPTPRHGHAAVLTDGKVYVIGGETK 262

                         90
                 ....*....|....*
gi 281371339  90 NQLP---VKVVEMYN 101
Cdd:COG3055  263 PGVRtplVTSAEVYD 277
PHA03098 PHA03098
kelch-like protein; Provisional
 1-108 5.36e-11

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 63.63  E-value: 5.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339   1 MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCD--DNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALG 78
Cdd:PHA03098 408 VECFSLNTNKWSKGSPLPISHYGGCAIYHDGKIYVIGGISyiDNIKVYNIVESYNPVTNKWTELSSLNFPRINASLCIFN 487

                         90       100       110
                 ....*....|....*....|....*....|
gi 281371339  79 KRIMVIGGVgTNQLPVKVVEMYNIDEGKWK 108
Cdd:PHA03098 488 NKIYVVGGD-KYEYYINEIEVYDDKTNTWT 516
Kelch smart00612
Kelch domain;
32-79 1.24e-10

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 56.03  E-value: 1.24e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 281371339    32 QVYAIGGCDdNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGK 79
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch smart00612
Kelch domain;
279-326 1.30e-09

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 53.33  E-value: 1.30e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 281371339   279 RVIVAGGLGNQpTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKN 326
Cdd:smart00612   1 KIYVVGGFDGG-QRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 20-66 1.39e-09

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 53.00  E-value: 1.39e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 281371339   20 RRVYCSLLETGGQVYAIGGCDdNGVPMDCFEVYSPEADQWTSLPSLP 66
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFD-GNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch smart00612
Kelch domain;
176-222 1.05e-06

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 44.86  E-value: 1.05e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 281371339   176 KIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDN 222
Cdd:smart00612   1 KIYVVGGFDGGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGVAVING 47
Kelch_6 pfam13964
Kelch motif;
278-316 3.08e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 43.86  E-value: 3.08e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 281371339  278 GRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPTPR 316
Cdd:pfam13964  12 GYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 267-313 3.91e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 43.37  E-value: 3.91e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 281371339  267 RRADFVAGGLSGRVIVAGGLGNQpTVLETAEAFHPEKNKWEALPPMP 313
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGN-QSLNSVEVYDPETNTWSKLPSMP 46
Kelch_6 pfam13964
Kelch motif;
164-212 5.23e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 43.09  E-value: 5.23e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 281371339  164 PRYAATSFLRGSKIYVLGGR-QSKYAVNAFEVFDIESRSWTKFPNIPCKR 212
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYtNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_6 pfam13964
Kelch motif;
21-69 6.24e-06

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 42.71  E-value: 6.24e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 281371339   21 RVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTAR 69
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
PHA02790 PHA02790
Kelch-like protein; Provisional
 129-337 7.63e-06

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 47.34  E-value: 7.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 129 VYAAGGMgLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIesrSWTKFPNI 208
Cdd:PHA02790 274 VYLIGGW-MNNEIHNNAIAVNYISNNWIPIPPMNSPRLYASGVPANNKLYVVGGLPNPTSVERWFHGDA---AWVNMPSL 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 209 PCKRAFSSFVTLDNHLYSLGGLRQGRlyrqpkflRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGglsGRVIVAGglgn 288
Cdd:PHA02790 350 LKPRCNPAVASINNVIYVIGGHSETD--------TTTEYLLPNHDQWQFGPSTYYPHYKSCALVFG---RRLFLVG---- 414

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 281371339 289 qptvlETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQG 337
Cdd:PHA02790 415 -----RNAEFYCESSNTWTLIDDPIYPRDNPELIIVDNKLLLIGGFYRG 458
PLN02193 PLN02193
nitrile-specifier protein
 174-333 1.12e-05

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 46.87  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 174 GSKIYVLGGRQSKYAVNAFEVFDIESRSW---TKFPNIPCKRAFSSFVTLDNHLYSLGGLrqGRLYRqpkfLRTMDVFDM 250
Cdd:PLN02193 228 GSTLYVFGGRDASRQYNGFYSFDTTTNEWkllTPVEEGPTPRSFHSMAADEENVYVFGGV--SATAR----LKTLDSYNI 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 251 EQGGWlkmersFFLKKRRADFVAGGLSGRVIVAGGL----GNQPTVLETAEAFHPEKNKW---EALPPMPTPRCACSSIV 323
Cdd:PLN02193 302 VDKKW------FHCSTPGDSFSIRGGAGLEVVQGKVwvvyGFNGCEVDDVHYYDPVQDKWtqvETFGVRPSERSVFASAA 375

                        170
                 ....*....|
gi 281371339 324 FKNCLLAVGG 333
Cdd:PLN02193 376 VGKHIVIFGG 385
PLN02153 PLN02153
epithiospecifier protein
 21-248 1.14e-05

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 46.52  E-value: 1.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  21 RVYC---SLLETGGQVYAIGGCDDNGVPMDcFEVYSPEADQWTSLPSL-----PTARAGVAITALGKRIMVIGGV---GT 89
Cdd:PLN02153  73 RISClgvRMVAVGTKLYIFGGRDEKREFSD-FYSYDTVKNEWTFLTKLdeeggPEARTFHSMASDENHVYVFGGVskgGL 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  90 NQLP--VKVVEMYNIDEGKWKK-----RSVLREAAMGISVT-AKDYRVYAAGGM----GLDLRPHNYLQHYDMLKDMWVS 157
Cdd:PLN02153 152 MKTPerFRTIEAYNIADGKWVQlpdpgENFEKRGGAGFAVVqGKIWVVYGFATSilpgGKSDYESNAVQFFDPASGKWTE 231

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 158 L---APMPTPRYAATSFLRGSKIYVLGGR-----QSKYA----VNAFEVFDIESRSWTKF-----PNIPckRAFSSFVTL 220
Cdd:PLN02153 232 VettGAKPSARSVFAHAVVGKYIIIFGGEvwpdlKGHLGpgtlSNEGYALDTETLVWEKLgecgePAMP--RGWTAYTTA 309

                        250       260       270
                 ....*....|....*....|....*....|
gi 281371339 221 DnhLYSLGGL--RQGRLyrqPKFLRTMDVF 248
Cdd:PLN02153 310 T--VYGKNGLlmHGGKL---PTNERTDDLY 334
Kelch_3 pfam13415
Galactose oxidase, central domain;
30-77 2.32e-05

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 41.12  E-value: 2.32e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 281371339   30 GGQVYAIGGCDDNGVPMDC-FEVYSPEADQWTSLPSLPTARAGVAITAL 77
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNdLYVYDLDTNTWTQIGDLPPPRSGHSATYI 49
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 164-207 8.80e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 39.52  E-value: 8.80e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 281371339  164 PRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPN 207
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPS 44
Kelch_6 pfam13964
Kelch motif;
118-165 1.30e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 39.24  E-value: 1.30e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 281371339  118 MGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPR 165
Cdd:pfam13964   3 TFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch smart00612
Kelch domain;
128-170 1.33e-04

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 39.08  E-value: 1.33e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 281371339   128 RVYAAGGMGlDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATS 170
Cdd:smart00612   1 KIYVVGGFD-GGQRLKSVEVYDPETNKWTPLPSMPTPRSGHGV 42
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 68-109 1.77e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 38.75  E-value: 1.77e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 281371339   68 ARAGVAITALGKRIMVIGGVGTNQlPVKVVEMYNIDEGKWKK 109
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ-SLNSVEVYDPETNTWSK 41
PHA02713 PHA02713
hypothetical protein; Provisional
 14-114 2.41e-04

hypothetical protein; Provisional


Pssm-ID: 165086 [Multi-domain]  Cd Length: 557  Bit Score: 42.69  E-value: 2.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  14 LAPLPSRRVYCSLLETGGQVYAIGGcdDNGVPMD-CFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGG--VGTN 90
Cdd:PHA02713 335 LPPMIKNRCRFSLAVIDDTIYAIGG--QNGTNVErTIECYTMGDDKWKMLPDMPIALSSYGMCVLDQYIYIIGGrtEHID 412

                         90       100
                 ....*....|....*....|....
gi 281371339  91 QLPVKVVEMYNIDEGKWKKRSVLR 114
Cdd:PHA02713 413 YTSVHHMNSIDMEEDTHSSNKVIR 436
Kelch_4 pfam13418
Galactose oxidase, central domain;
20-67 3.26e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.98  E-value: 3.26e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 281371339   20 RRVYCSLLETG-GQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPT 67
Cdd:pfam13418   1 PRAYHTSTSIPdDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
PHA02790 PHA02790
Kelch-like protein; Provisional
 166-332 3.41e-04

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 42.34  E-value: 3.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 166 YAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGLrqgrlyrqPKFLRTM 245
Cdd:PHA02790 263 HMCTSTHVGEVVYLIGGWMNNEIHNNAIAVNYISNNWIPIPPMNSPRLYASGVPANNKLYVVGGL--------PNPTSVE 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339 246 DVFDMEQgGWLKMERsffLKKRRADFVAGGLSGRVIVAGGLGNQPTvleTAEAFHPEKNKWEALPPMPTPRCACSSIVFK 325
Cdd:PHA02790 335 RWFHGDA-AWVNMPS---LLKPRCNPAVASINNVIYVIGGHSETDT---TTEYLLPNHDQWQFGPSTYYPHYKSCALVFG 407


                 ....*..
gi 281371339 326 NCLLAVG 332
Cdd:PHA02790 408 RRLFLVG 414
PLN02193 PLN02193
nitrile-specifier protein
 31-86 2.14e-03

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 39.94  E-value: 2.14e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 281371339  31 GQVYAIGGCddNGVPMDCFEVYSPEADQWTSLPSL---PTARAGVAITALGKRIMVIGG 86
Cdd:PLN02193 329 GKVWVVYGF--NGCEVDDVHYYDPVQDKWTQVETFgvrPSERSVFASAAVGKHIVIFGG 385
PHA02713 PHA02713
hypothetical protein; Provisional
 99-252 2.68e-03

hypothetical protein; Provisional


Pssm-ID: 165086 [Multi-domain]  Cd Length: 557  Bit Score: 39.61  E-value: 2.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  99 MYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIY 178
Cdd:PHA02713 276 VYNINTMEYSVISTIPNHIINYASAIVDNEIIIAGGYNFNNPSLNKVYKINIENKIHVELPPMIKNRCRFSLAVIDDTIY 355

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 281371339 179 VLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGLRQGRLYRQpkfLRTMDVFDMEQ 252
Cdd:PHA02713 356 AIGGQNGTNVERTIECYTMGDDKWKMLPDMPIALSSYGMCVLDQYIYIIGGRTEHIDYTS---VHHMNSIDMEE 426
Kelch_4 pfam13418
Galactose oxidase, central domain;
267-314 3.05e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 35.28  E-value: 3.05e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 281371339  267 RRADFVAGGL-SGRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPT 314
Cdd:pfam13418   1 PRAYHTSTSIpDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
Kelch_4 pfam13418
Galactose oxidase, central domain;
164-210 3.64e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.90  E-value: 3.64e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 281371339  164 PR-YAATSFLRGSKIYVLGGRQSKYAV-NAFEVFDIESRSWTKFPNIPC 210
Cdd:pfam13418   1 PRaYHTSTSIPDDTIYLFGGEGEDGTLlSDLWVFDLSTNEWTRLGSLPS 49
Kelch smart00612
Kelch domain;
80-124 4.99e-03

Kelch domain;


Pssm-ID: 128874 [Multi-domain]  Cd Length: 47  Bit Score: 34.46  E-value: 4.99e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 281371339    80 RIMVIGGVGTNQlPVKVVEMYNIDEGKWKKRSVLREAAMGISVTA 124
Cdd:smart00612   1 KIYVVGGFDGGQ-RLKSVEVYDPETNKWTPLPSMPTPRSGHGVAV 44
PHA02790 PHA02790
Kelch-like protein; Provisional
 11-202 5.98e-03

Kelch-like protein; Provisional


Pssm-ID: 165153 [Multi-domain]  Cd Length: 480  Bit Score: 38.49  E-value: 5.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  11 WKRLAPLPSRRVYCSLLETGGQVYAIGGCDDngvPMDCFEVYSPEAdQWTSLPSLPTARAGVAITALGKRIMVIGGVGTN 90
Cdd:PHA02790 299 WIPIPPMNSPRLYASGVPANNKLYVVGGLPN---PTSVERWFHGDA-AWVNMPSLLKPRCNPAVASINNVIYVIGGHSET 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281371339  91 QlpvKVVEMYNIDEGKWKkrsvlreaaMGISVTAKDYRVYA-AGGMGLDLRPHNyLQHYDMLKDMWVSLAPMPTPRYAAT 169
Cdd:PHA02790 375 D---TTTEYLLPNHDQWQ---------FGPSTYYPHYKSCAlVFGRRLFLVGRN-AEFYCESSNTWTLIDDPIYPRDNPE 441

                        170       180       190
                 ....*....|....*....|....*....|...
gi 281371339 170 SFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSW 202
Cdd:PHA02790 442 LIIVDNKLLLIGGFYRGSYIDTIEVYNNRTYSW 474
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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