NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|158187542|ref|NP_001094129|]
View 

cell division cycle protein 23 homolog [Rattus norvegicus]

Protein Classification

ANAPC8 and TPR domain-containing protein( domain architecture ID 12049631)

ANAPC8 and TPR domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ANAPC8 pfam04049
Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of ...
 45-148 1.25e-31

Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).


:

Pssm-ID: 427675  Cd Length: 140  Bit Score: 119.24  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542   45 ERGLLHSSKWSAELAFSLPALPL-------------SELQPPPPLTEED-------AQDVDAYTLAKAYFDVKEYDRAAH 104
Cdd:pfam04049  15 ERCLYQSAKWAAELLNGLPPPDDdddpsdtdpdspmSESPLPARTPNPDpeearleAKEYDKYLLAKSYFDCKEFDRCAA 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 158187542  105 FLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKN 148
Cdd:pfam04049  95 VLKDCKSQKSLFLALYAKYLAGEKRKEEESEMVLGPQDGGNTVN 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
325-495 1.10e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.16  E-value: 1.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 325 EIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 405 LGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESE 484
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|.
gi 158187542 485 QAAQCYIKYIQ 495
Cdd:COG0457  162 EALELLEKLEA 172
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 234-405 1.51e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 1.51e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 234 LAHIYTELQLIEEALQKYQHLIDVgFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLlyvrsmk 313
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALAL-NPDNAEALFNLGNLLLALGRLEEALAALRRALALNP---DFAEAYLNL------- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 314 selsylahnlceidkyrvetccviGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393
Cdd:COG3914  153 ------------------------GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208

                        170
                 ....*....|..
gi 158187542 394 VNKRDYRAWYGL 405
Cdd:COG3914  209 LDPDNADAHSNL 220
 
Name Accession Description Interval E-value
ANAPC8 pfam04049
Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of ...
 45-148 1.25e-31

Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).


Pssm-ID: 427675  Cd Length: 140  Bit Score: 119.24  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542   45 ERGLLHSSKWSAELAFSLPALPL-------------SELQPPPPLTEED-------AQDVDAYTLAKAYFDVKEYDRAAH 104
Cdd:pfam04049  15 ERCLYQSAKWAAELLNGLPPPDDdddpsdtdpdspmSESPLPARTPNPDpeearleAKEYDKYLLAKSYFDCKEFDRCAA 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 158187542  105 FLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKN 148
Cdd:pfam04049  95 VLKDCKSQKSLFLALYAKYLAGEKRKEEESEMVLGPQDGGNTVN 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
325-495 1.10e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.16  E-value: 1.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 325 EIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 405 LGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESE 484
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|.
gi 158187542 485 QAAQCYIKYIQ 495
Cdd:COG0457  162 EALELLEKLEA 172
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 234-405 1.51e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 1.51e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 234 LAHIYTELQLIEEALQKYQHLIDVgFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLlyvrsmk 313
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALAL-NPDNAEALFNLGNLLLALGRLEEALAALRRALALNP---DFAEAYLNL------- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 314 selsylahnlceidkyrvetccviGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393
Cdd:COG3914  153 ------------------------GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208

                        170
                 ....*....|..
gi 158187542 394 VNKRDYRAWYGL 405
Cdd:COG3914  209 LDPDNADAHSNL 220
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 344-407 1.12e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 50.70  E-value: 1.12e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158187542 344 RSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN-KRDYRAWYGLGQ 407
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpDGGYEKYLYLGQ 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 336-529 1.88e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  336 VIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMP 415
Cdd:TIGR02917 606 MLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRT 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  416 FYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKmALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:TIGR02917 686 ESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ-NAIKLHRALLASGNTAEAVKTLEAWLK 764

                         170       180       190
                  ....*....|....*....|....*....|....
gi 158187542  496 diyscgetvEHLEESTAFRYLAQYYFKCKLWDEA 529
Cdd:TIGR02917 765 ---------THPNDAVLRTALAELYLAQKDYDKA 789
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 273-491 1.09e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 44.80  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 273 YHNIRDIDKALSIFNELRK--QDPYRIEnmdtfsnllyvrsmkselsyLAHNLCEIdkyrvetccviGNYYSLRSQHEKA 350
Cdd:PRK11788 151 YQQEKDWQKAIDVAERLEKlgGDSLRVE--------------------IAHFYCEL-----------AQQALARGDLDAA 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 351 ALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKrDYRAwyglgqtyEILKMpfyclyyyrrahqlrp 430
Cdd:PRK11788 200 RALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDP-EYLS--------EVLPK---------------- 254

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158187542 431 ndsrmlvaLGECYEKLNQLVEAKKC---YWRAYAVGDVEKMalvkLAKLHEQLtESEQAAQCYI 491
Cdd:PRK11788 255 --------LMECYQALGDEAEGLEFlrrALEEYPGADLLLA----LAQLLEEQ-EGPEAAQALL 305
TPR_11 pfam13414
TPR repeat;
372-410 1.36e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.36e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 158187542  372 GHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYE 410
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYY 39
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 367-398 7.14e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 7.14e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 158187542   367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRD 398
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
ANAPC8 pfam04049
Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of ...
 45-148 1.25e-31

Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).


Pssm-ID: 427675  Cd Length: 140  Bit Score: 119.24  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542   45 ERGLLHSSKWSAELAFSLPALPL-------------SELQPPPPLTEED-------AQDVDAYTLAKAYFDVKEYDRAAH 104
Cdd:pfam04049  15 ERCLYQSAKWAAELLNGLPPPDDdddpsdtdpdspmSESPLPARTPNPDpeearleAKEYDKYLLAKSYFDCKEFDRCAA 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 158187542  105 FLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKN 148
Cdd:pfam04049  95 VLKDCKSQKSLFLALYAKYLAGEKRKEEESEMVLGPQDGGNTVN 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
325-495 1.10e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 103.16  E-value: 1.10e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 325 EIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 405 LGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESE 484
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|.
gi 158187542 485 QAAQCYIKYIQ 495
Cdd:COG0457  162 EALELLEKLEA 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 228-495 4.48e-23

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.42  E-value: 4.48e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 228 WMKEFFLAHIYTELQLIEEALQKYQHLIDVgFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM-----DT 302
Cdd:COG2956    8 ALGWYFKGLNYLLNGQPDKAIDLLEEALEL-DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALlelaqDY 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 303 FSNLLYVRSMKselsyLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTS 382
Cdd:COG2956   87 LKAGLLDRAEE-----LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 383 AAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV 462
Cdd:COG2956  162 EAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALEL 241

                        250       260       270
                 ....*....|....*....|....*....|...
gi 158187542 463 gDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:COG2956  242 -DPSDDLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 254-529 2.20e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 97.11  E-value: 2.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 254 LIDVGFSKSSYIVsqiAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVET 333
Cdd:COG2956    2 LLPVAAALGWYFK---GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 334 CCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILK 413
Cdd:COG2956   79 LLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 414 MPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKY 493
Cdd:COG2956  159 DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKA 238

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 158187542 494 iqdiyscgetVEHLEESTAFRYLAQYYFKCKLWDEA 529
Cdd:COG2956  239 ----------LELDPSDDLLLALADLLERKEGLEAA 264
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 338-561 1.95e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 88.63  E-value: 1.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFY 417
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 418 CLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDI 497
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158187542 498 YSCGEtvehleestAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGE 561
Cdd:COG2956  175 PDCAR---------ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPE 229
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 322-561 2.25e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 88.63  E-value: 2.25e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 322 NLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRA 401
Cdd:COG2956   33 EALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 402 WYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLT 481
Cdd:COG2956  113 LRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 482 ESEQAAQCYIKYIQdiyscgetvEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGE 561
Cdd:COG2956  193 DYEEAIAALERALE---------QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEA 263
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
358-561 7.29e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 86.21  E-value: 7.29e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 358 LKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLV 437
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 438 ALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQdiyscgetvEHLEESTAFRYLA 517
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALE---------LDPDDADALYNLG 151

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 158187542 518 QYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGE 561
Cdd:COG0457  152 IALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEV 195
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 338-461 1.90e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 89.28  E-value: 1.90e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFY 417
Cdd:COG3914   85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 158187542 418 CLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYA 461
Cdd:COG3914  165 AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 337-461 7.16e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.84  E-value: 7.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPF 416
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 158187542 417 YCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYA 461
Cdd:COG4783   90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 340-545 5.05e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 78.50  E-value: 5.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 340 YYSLRSQHEKAALYFQRALKLNPRYLGAWtlmgheYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCL 419
Cdd:COG3914   59 LLALAAGEAAAAAAALLLLAALLELAALL------LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEAL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 420 YYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV--GDVEkmALVKLAKLHEQLTESEQAAQCYIKYIQdi 497
Cdd:COG3914  133 AALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELdpDNAE--ALNNLGNALQDLGRLEEAIAAYRRALE-- 208

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 158187542 498 yscgetvEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREE 545
Cdd:COG3914  209 -------LDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSE 249
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 325-432 2.36e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 76.19  E-value: 2.36e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 325 EIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404
Cdd:COG3914  106 ALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185

                         90       100
                 ....*....|....*....|....*...
gi 158187542 405 LGQTYEILKMPFYCLYYYRRAHQLRPND 432
Cdd:COG3914  186 LGNALQDLGRLEEAIAAYRRALELDPDN 213
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 268-432 5.62e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 5.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 268 QIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLlyvrsmkselsylahnlceidkyrvetccviGNYYSLRSQH 347
Cdd:COG4783    9 ALAQALLLAGDYDEAEALLEKALELDP---DNPEAFALL-------------------------------GEILLQLGDL 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQ 427
Cdd:COG4783   55 DEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134


                 ....*
gi 158187542 428 LRPND 432
Cdd:COG4783  135 LDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 349-459 1.79e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 67.34  E-value: 1.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 349 KAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQL 428
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|.
gi 158187542 429 RPNDSRMLVALGECYEKLNQLVEAKKcYWRA 459
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIA-AWQK 110
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 337-433 1.87e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 1.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPF 416
Cdd:COG4235   23 LGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYA 102

                         90
                 ....*....|....*..
gi 158187542 417 YCLYYYRRAHQLRPNDS 433
Cdd:COG4235  103 EAIAAWQKLLALLPADA 119
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 234-405 1.51e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 1.51e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 234 LAHIYTELQLIEEALQKYQHLIDVgFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLlyvrsmk 313
Cdd:COG3914   84 AALLLQALGRYEEALALYRRALAL-NPDNAEALFNLGNLLLALGRLEEALAALRRALALNP---DFAEAYLNL------- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 314 selsylahnlceidkyrvetccviGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393
Cdd:COG3914  153 ------------------------GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208

                        170
                 ....*....|..
gi 158187542 394 VNKRDYRAWYGL 405
Cdd:COG3914  209 LDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 367-495 2.77e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 2.77e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKL 446
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 158187542 447 NQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
340-431 5.35e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.33  E-value: 5.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 340 YYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQaYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCL 419
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|..
gi 158187542 420 YYYRRAHQLRPN 431
Cdd:COG3063   80 AYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 368-535 6.24e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.51  E-value: 6.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 368 WTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLN 447
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 448 QLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQdiyscgetvEHLEESTAFRYLAQYYFKCKLWD 527
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK---------LGPENAHAYCELAELYLEQGDYD 161


                 ....*...
gi 158187542 528 EASTCAQK 535
Cdd:COG2956  162 EAIEALEK 169
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 383-495 9.51e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.94  E-value: 9.51e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 383 AAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV 462
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 158187542 463 GDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA 113
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
338-448 5.11e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.85  E-value: 5.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFY 417
Cdd:COG4785   80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                         90       100       110
                 ....*....|....*....|....*....|.
gi 158187542 418 CLYYYRRAHQLRPNDSRMLVALGECYEKLNQ 448
Cdd:COG4785  160 AIADLEKALELDPNDPERALWLYLAERKLDP 190
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 375-461 9.60e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.58  E-value: 9.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 375 YMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                 ....*..
gi 158187542 455 CYWRAYA 461
Cdd:COG5010  144 ALQRALG 150
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 341-430 2.46e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 2.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 341 YSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY 420
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                         90
                 ....*....|
gi 158187542 421 YYRRAHQLRP 430
Cdd:COG5010  144 ALQRALGTSP 153
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 337-538 3.46e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.54  E-value: 3.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR---DYRAWYGLGQTYEILK 413
Cdd:COG3914   13 AAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAAlllLAALLELAALLLQALG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 414 MPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKY 493
Cdd:COG3914   93 RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRA 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 158187542 494 IQdiyscgetvEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCA 538
Cdd:COG3914  173 LE---------LDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 344-407 1.12e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 50.70  E-value: 1.12e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158187542 344 RSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN-KRDYRAWYGLGQ 407
Cdd:cd24142   13 QGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpDGGYEKYLYLGQ 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
172-401 1.85e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 1.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 172 LYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWlelcnlitdkemlkflslpdtwmkeFFLAHIYTELQLIEEALQKY 251
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEAL-------------------------YNLGLAYLRLGRYEEALADY 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 252 QHLIDVGfSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLlyvrsmkselsylahnlceidkyrv 331
Cdd:COG0457   66 EQALELD-PDDAEALNNLGLALQALGRYEEALEDYDKALELDP---DDAEALYNL------------------------- 116

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 332 etccviGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRA 401
Cdd:COG0457  117 ------GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 374-456 1.27e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.60  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 374 EYMEMKNTSAAIQAYRHAIEVNKRDY---RAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSR---MLVALGECYEKLN 447
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELG 81


                 ....*....
gi 158187542 448 QLVEAKKCY 456
Cdd:COG1729   82 DYDKARATL 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 336-529 1.88e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  336 VIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMP 415
Cdd:TIGR02917 606 MLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRT 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  416 FYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKmALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:TIGR02917 686 ESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ-NAIKLHRALLASGNTAEAVKTLEAWLK 764

                         170       180       190
                  ....*....|....*....|....*....|....
gi 158187542  496 diyscgetvEHLEESTAFRYLAQYYFKCKLWDEA 529
Cdd:TIGR02917 765 ---------THPNDAVLRTALAELYLAQKDYDKA 789
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
421-495 2.42e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 2.42e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 158187542 421 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKcYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:COG3063   14 YYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALE 87
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 269-492 3.54e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 3.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  269 IAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLLYVRSMKSELSYLAHNL---CEIDKyrvetccviGNYYSLRS 345
Cdd:TIGR02917 437 LILSYLRSGQFDKALAAAKKLEKKQP---DNASLHNLLGAIYLGKGDLAKAREAFekaLSIEP---------DFFPAAAN 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  346 QH---------EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPF 416
Cdd:TIGR02917 505 LAridiqegnpDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLK 584

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158187542  417 YCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIK 492
Cdd:TIGR02917 585 KALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKR 660
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
325-400 3.95e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 3.95e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158187542 325 EIDKYRVETCCVIGNYYSLRSQHEKAaLYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYR 400
Cdd:COG3063   20 ELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSALR 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 383-495 6.45e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 6.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 383 AAIQAYRHAIEVNKRDYRAWYGLGQTYEILKmpfyclyYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV 462
Cdd:COG5010   45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLA-------LLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL 117

                         90       100       110
                 ....*....|....*....|....*....|...
gi 158187542 463 GDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:COG5010  118 SPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 422-556 8.06e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 8.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 422 YRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQdiyscg 501
Cdd:COG4235    6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA------ 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 158187542 502 etvEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQL 556
Cdd:COG4235   80 ---LDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 273-491 1.09e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 44.80  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 273 YHNIRDIDKALSIFNELRK--QDPYRIEnmdtfsnllyvrsmkselsyLAHNLCEIdkyrvetccviGNYYSLRSQHEKA 350
Cdd:PRK11788 151 YQQEKDWQKAIDVAERLEKlgGDSLRVE--------------------IAHFYCEL-----------AQQALARGDLDAA 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 351 ALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKrDYRAwyglgqtyEILKMpfyclyyyrrahqlrp 430
Cdd:PRK11788 200 RALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQDP-EYLS--------EVLPK---------------- 254

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 158187542 431 ndsrmlvaLGECYEKLNQLVEAKKC---YWRAYAVGDVEKMalvkLAKLHEQLtESEQAAQCYI 491
Cdd:PRK11788 255 --------LMECYQALGDEAEGLEFlrrALEEYPGADLLLA----LAQLLEEQ-EGPEAAQALL 305
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 337-495 1.78e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 44.69  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  337 IGNYYSLRSQHEKAALYFQRALKLNP---------------RYlgaWTLM--GHEYMEMKNTSAAIQAYRHAIEVNKRDY 399
Cdd:PRK11447  309 LGQAYSQQGDRARAVAQFEKALALDPhssnrdkwesllkvnRY---WLLIqqGDAALKANNLAQAERLYQQARQVDNTDS 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  400 RAWYGLGQTYEILKMPFYCLYYYRRAHQLRP-NDS--RMLVAL--GECYEK----LNQLVEAKKcywraYAVGDVEK-MA 469
Cdd:PRK11447  386 YAVLGLGDVAMARKDYAAAERYYQQALRMDPgNTNavRGLANLyrQQSPEKalafIASLSASQR-----RSIDDIERsLQ 460

                         170       180
                  ....*....|....*....|....*.
gi 158187542  470 LVKLAKLHEQLTESEQAAQCYIKYIQ 495
Cdd:PRK11447  461 NDRLAQQAEALENQGKWAQAAELQRQ 486
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 278-456 1.85e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 1.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  278 DIDKALSIFNELRKQDPYRIEnmdTFSNLLYVRSMKSE----LSYLAHNLcEIDKYRVETCCVIGNYYSLRSQHEKAALY 353
Cdd:TIGR02917 616 DLNKAVSSFKKLLALQPDSAL---ALLLLADAYAVMKNyakaITSLKRAL-ELKPDNTEAQIGLAQLLLAAKRTESAKKI 691

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542  354 FQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRD------YRAWYGLGQTYEILKMpfycLYYYRRAHq 427
Cdd:TIGR02917 692 AKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSqnaiklHRALLASGNTAEAVKT----LEAWLKTH- 766

                         170       180
                  ....*....|....*....|....*....
gi 158187542  428 lrPNDSRMLVALGECYEKLNQLVEAKKCY 456
Cdd:TIGR02917 767 --PNDAVLRTALAELYLAQKDYDKAIKHY 793
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 398-455 1.99e-04

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 41.51  E-value: 1.99e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 158187542  398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKC 455
Cdd:TIGR02552  50 NSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGEPESALKA 107
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 397-535 8.88e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 8.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 397 RDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKL 476
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 158187542 477 HEQLTESEQAAQCYIKYIQdiyscgetvEHLEESTAFRYLAQYYFKCKLWDEASTCAQK 535
Cdd:COG4783   82 LLKAGDYDEALALLEKALK---------LDPEHPEAYLRLARAYRALGRPDEAIAALEK 131
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 172-364 1.06e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 172 LYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLElcnlitdkemlkflslpdtwmkeffLAHIYTELQLIEEALQKY 251
Cdd:COG3914  115 LFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLN-------------------------LGEALRRLGRLEEAIAAL 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 252 QHLIDVgFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFSNLLYVRsMKSELSYLAHNLCEIDKYRV 331
Cdd:COG3914  170 RRALEL-DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP---DNADAHSNLLFAL-RQACDWEVYDRFEELLAALA 244

                        170       180       190
                 ....*....|....*....|....*....|...
gi 158187542 332 ETCCVIGNYYSLRSQHEKAALYFQRALKLNPRY 364
Cdd:COG3914  245 RGPSELSPFALLYLPDDDPAELLALARAWAQLV 277
TPR_11 pfam13414
TPR repeat;
372-410 1.36e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.36e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 158187542  372 GHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYE 410
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYY 39
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 418-495 1.54e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 41.07  E-value: 1.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 418 CLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV---GDVEKmaLVKLAklheQLTESEQAAQCYIKYI 494
Cdd:cd24142   19 ALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELdpdGGYEK--YLYLG----QLSGGEEALQYYEKGI 92


                 .
gi 158187542 495 Q 495
Cdd:cd24142   93 E 93
TPR_1 pfam00515
Tetratricopeptide repeat;
331-364 2.72e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 2.72e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 158187542  331 VETCCVIGNYYSLRSQHEKAALYFQRALKLNPRY 364
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 371-436 4.04e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 39.24  E-value: 4.04e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158187542  371 MGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRML 436
Cdd:TIGR02521  37 LALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVL 102
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 337-396 4.24e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 4.24e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK 396
Cdd:COG5010   94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 424-490 4.33e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.51  E-value: 4.33e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 158187542 424 RAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVG-DVEkmALVKLAKLHEQLTESEQAAQCY 490
Cdd:COG3071  249 KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRpSAE--AYAELARLLEQLGDPEEAAEHY 314
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 225-362 4.37e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 4.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 225 PDTWMkefFLAHIYTELQLIEEALQKYQHLIDVgFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPyriENMDTFS 304
Cdd:COG4235   17 AEGWL---LLGRAYLRLGRYDEALAAYEKALRL-DPDNADALLDLAEALLAAGDTEEAEELLERALALDP---DNPEALY 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 158187542 305 NLlyvrsmkselsylahnlceidkyrvetccviGNYYSLRSQHEKAALYFQRALKLNP 362
Cdd:COG4235   90 LL-------------------------------GLAAFQQGDYAEAIAAWQKLLALLP 116
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 346-433 5.08e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 5.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158187542 346 QHEKAALYFQRALKLNPR--YLG-AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYR---AWYGLGQTYEILKMPFYCL 419
Cdd:COG1729    8 DYDEAIAAFKAFLKRYPNspLAPdALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKAR 87

                         90
                 ....*....|....
gi 158187542 420 YYYRRAHQLRPNDS 433
Cdd:COG1729   88 ATLEELIKKYPDSE 101
TPR_1 pfam00515
Tetratricopeptide repeat;
367-398 5.97e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 5.97e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 158187542  367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRD 398
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 367-398 7.14e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 7.14e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 158187542   367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRD 398
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH