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Conserved domains on  [gi|161377437|ref|NP_001094121|]
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phosphatidylinositol-glycan biosynthesis class X protein precursor [Rattus norvegicus]

Protein Classification

PIG-X/PBN1 family protein( domain architecture ID 10550877)

PIG-X/PBN1 family protein similar to human phosphatidylinositol-glycan biosynthesis class X protein, an essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PIG-X pfam08320
PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of ...
 48-244 1.66e-54

PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.


:

Pssm-ID: 462426  Cd Length: 207  Bit Score: 174.47  E-value: 1.66e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437   48 KDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPTGLFVDPYELASLRERNitEAVMVSESFNLEAPSYLSTE--SAVLI- 124
Cdd:pfam08320   1 PTGLHPTLQLTLSSASLKPPDKECKLHAYLTLPSSVFVDKYQLASLDPLF--ALVLLSGEVDLEAPEYKISEwgSEVLLe 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437  125 ---YARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMHCDQEFPIlkcwAQSEVAAPCSLKS-------EE 194
Cdd:pfam08320  79 lapPPTTDNSSPGEWTVTLPLHLRYLRPSSESGYTTVELPWPVVFWACDSTAEE----GTLLVKNPFDRVNlgydglfGP 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 161377437  195 ICQWKNMQYKSI---LKNLTVQVPVGLTIHTSLVCSVTLLITVLCSTLILLAV 244
Cdd:pfam08320 155 KTVFYHLHPSPApgsVLVLSLEVPVGDTSHAAWVEIGTLLVVLLGFLWILWKL 207
 
Name Accession Description Interval E-value
PIG-X pfam08320
PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of ...
 48-244 1.66e-54

PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.


Pssm-ID: 462426  Cd Length: 207  Bit Score: 174.47  E-value: 1.66e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437   48 KDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPTGLFVDPYELASLRERNitEAVMVSESFNLEAPSYLSTE--SAVLI- 124
Cdd:pfam08320   1 PTGLHPTLQLTLSSASLKPPDKECKLHAYLTLPSSVFVDKYQLASLDPLF--ALVLLSGEVDLEAPEYKISEwgSEVLLe 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437  125 ---YARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMHCDQEFPIlkcwAQSEVAAPCSLKS-------EE 194
Cdd:pfam08320  79 lapPPTTDNSSPGEWTVTLPLHLRYLRPSSESGYTTVELPWPVVFWACDSTAEE----GTLLVKNPFDRVNlgydglfGP 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 161377437  195 ICQWKNMQYKSI---LKNLTVQVPVGLTIHTSLVCSVTLLITVLCSTLILLAV 244
Cdd:pfam08320 155 KTVFYHLHPSPApgsVLVLSLEVPVGDTSHAAWVEIGTLLVVLLGFLWILWKL 207
PIG-X smart00780
PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of ...
 50-246 3.03e-38

PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.


Pssm-ID: 197872  Cd Length: 203  Bit Score: 132.52  E-value: 3.03e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437    50 GFHRDLLIKVKFGESIEDLQTCRLLIKHYIPTGLFVDPYELASLRERNITEAVMVSESFNLEAPSYLSTE--SAVLIYAR 127
Cdd:smart00780   4 GLHPKLEIDLTSIPPDEDDEECALHAYLTLPSTLFIDKYQLSFLAHHNLTTLRLLFGEVDLEAPEYKLNGwgSEVLFELA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437   128 QDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMHCDQEFPILKCWAQSEVAAPCSLKSEEICQWKNMQYKSIL 207
Cdd:smart00780  84 PDDGCAKGWINTVPLHLRYLRPASGTGYVSIELPNPKVFWACDTEDGTLSCSPFDVTGLGYEGLFTEDTVFYHLNPTPDP 163

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 161377437   208 KNLTVQVPVGLTIHTSLVCSVTLLITVLCSTLILLAVFK 246
Cdd:smart00780 164 GSLEINVPVGDTSDFPVIELVTLLVVLIGFLYILYKLFR 202
 
Name Accession Description Interval E-value
PIG-X pfam08320
PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of ...
 48-244 1.66e-54

PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.


Pssm-ID: 462426  Cd Length: 207  Bit Score: 174.47  E-value: 1.66e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437   48 KDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPTGLFVDPYELASLRERNitEAVMVSESFNLEAPSYLSTE--SAVLI- 124
Cdd:pfam08320   1 PTGLHPTLQLTLSSASLKPPDKECKLHAYLTLPSSVFVDKYQLASLDPLF--ALVLLSGEVDLEAPEYKISEwgSEVLLe 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437  125 ---YARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMHCDQEFPIlkcwAQSEVAAPCSLKS-------EE 194
Cdd:pfam08320  79 lapPPTTDNSSPGEWTVTLPLHLRYLRPSSESGYTTVELPWPVVFWACDSTAEE----GTLLVKNPFDRVNlgydglfGP 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 161377437  195 ICQWKNMQYKSI---LKNLTVQVPVGLTIHTSLVCSVTLLITVLCSTLILLAV 244
Cdd:pfam08320 155 KTVFYHLHPSPApgsVLVLSLEVPVGDTSHAAWVEIGTLLVVLLGFLWILWKL 207
PIG-X smart00780
PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of ...
 50-246 3.03e-38

PIG-X / PBN1; Mammalian PIG-X and yeast PBN1 are essential components of glycosylphosphatidylinositol-mannosyltransferase I. These enzymes are involved in the transfer of sugar molecules.


Pssm-ID: 197872  Cd Length: 203  Bit Score: 132.52  E-value: 3.03e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437    50 GFHRDLLIKVKFGESIEDLQTCRLLIKHYIPTGLFVDPYELASLRERNITEAVMVSESFNLEAPSYLSTE--SAVLIYAR 127
Cdd:smart00780   4 GLHPKLEIDLTSIPPDEDDEECALHAYLTLPSTLFIDKYQLSFLAHHNLTTLRLLFGEVDLEAPEYKLNGwgSEVLFELA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161377437   128 QDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMHCDQEFPILKCWAQSEVAAPCSLKSEEICQWKNMQYKSIL 207
Cdd:smart00780  84 PDDGCAKGWINTVPLHLRYLRPASGTGYVSIELPNPKVFWACDTEDGTLSCSPFDVTGLGYEGLFTEDTVFYHLNPTPDP 163

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 161377437   208 KNLTVQVPVGLTIHTSLVCSVTLLITVLCSTLILLAVFK 246
Cdd:smart00780 164 GSLEINVPVGDTSDFPVIELVTLLVVLIGFLYILYKLFR 202
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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