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Conserved domains on  [gi|145329202|ref|NP_001077930|]
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Translocon-associated protein (TRAP), alpha subunit [Arabidopsis thaliana]

Protein Classification

translocon-associated protein subunit alpha( domain architecture ID 4307)

translocon-associated protein subunit alpha is part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins

Gene Ontology:  GO:0005789|GO:0005509
TCDB:  3.A.5

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TRAP_alpha super family cl04314
Translocon-associated protein (TRAP), alpha subunit; The alpha-subunit of the TRAP complex ...
 26-181 5.24e-19

Translocon-associated protein (TRAP), alpha subunit; The alpha-subunit of the TRAP complex (TRAP alpha) is a single-spanning membrane protein of the endoplasmic reticulum (ER) which is found in proximity of nascent polypeptide chains translocating across the membrane.


The actual alignment was detected with superfamily member pfam03896:

Pssm-ID: 461085  Cd Length: 279  Bit Score: 82.06  E-value: 5.24e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145329202   26 SDAEDHSSLVDDVVGENTDDAVEEDDhdldMNLSSFPGVETVCVF--PKNSAKLVPAGEETELLVGLKNEGKTRVGVMGI 103
Cdd:pfam03896  36 VEGEDEEVVGEDAESETEEEEEEEDE----DELKSSPDADTTILFtkPAGTGLELPAGEIVEFLVGFTNKGSEDFVVESL 111

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145329202  104 RASVHLPYDHKLLVQNLTMLRLnNASIPTSLQATFPYIFAVSQYLQPGAFDLVGYIIY-DVEGKPYQSVFYNGTIEVVE 181
Cdd:pfam03896 112 EASFRYPMDFNFYIQNFTALPY-NTVVKPGHQATFAYSFIPAEAFAGRPFGLVINLNYrDTEGNQFQEAVFNETVNIVE 189
 
Name Accession Description Interval E-value
TRAP_alpha pfam03896
Translocon-associated protein (TRAP), alpha subunit; The alpha-subunit of the TRAP complex ...
 26-181 5.24e-19

Translocon-associated protein (TRAP), alpha subunit; The alpha-subunit of the TRAP complex (TRAP alpha) is a single-spanning membrane protein of the endoplasmic reticulum (ER) which is found in proximity of nascent polypeptide chains translocating across the membrane.


Pssm-ID: 461085  Cd Length: 279  Bit Score: 82.06  E-value: 5.24e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145329202   26 SDAEDHSSLVDDVVGENTDDAVEEDDhdldMNLSSFPGVETVCVF--PKNSAKLVPAGEETELLVGLKNEGKTRVGVMGI 103
Cdd:pfam03896  36 VEGEDEEVVGEDAESETEEEEEEEDE----DELKSSPDADTTILFtkPAGTGLELPAGEIVEFLVGFTNKGSEDFVVESL 111

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145329202  104 RASVHLPYDHKLLVQNLTMLRLnNASIPTSLQATFPYIFAVSQYLQPGAFDLVGYIIY-DVEGKPYQSVFYNGTIEVVE 181
Cdd:pfam03896 112 EASFRYPMDFNFYIQNFTALPY-NTVVKPGHQATFAYSFIPAEAFAGRPFGLVINLNYrDTEGNQFQEAVFNETVNIVE 189
 
Name Accession Description Interval E-value
TRAP_alpha pfam03896
Translocon-associated protein (TRAP), alpha subunit; The alpha-subunit of the TRAP complex ...
 26-181 5.24e-19

Translocon-associated protein (TRAP), alpha subunit; The alpha-subunit of the TRAP complex (TRAP alpha) is a single-spanning membrane protein of the endoplasmic reticulum (ER) which is found in proximity of nascent polypeptide chains translocating across the membrane.


Pssm-ID: 461085  Cd Length: 279  Bit Score: 82.06  E-value: 5.24e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145329202   26 SDAEDHSSLVDDVVGENTDDAVEEDDhdldMNLSSFPGVETVCVF--PKNSAKLVPAGEETELLVGLKNEGKTRVGVMGI 103
Cdd:pfam03896  36 VEGEDEEVVGEDAESETEEEEEEEDE----DELKSSPDADTTILFtkPAGTGLELPAGEIVEFLVGFTNKGSEDFVVESL 111

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 145329202  104 RASVHLPYDHKLLVQNLTMLRLnNASIPTSLQATFPYIFAVSQYLQPGAFDLVGYIIY-DVEGKPYQSVFYNGTIEVVE 181
Cdd:pfam03896 112 EASFRYPMDFNFYIQNFTALPY-NTVVKPGHQATFAYSFIPAEAFAGRPFGLVINLNYrDTEGNQFQEAVFNETVNIVE 189
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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