|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
620-1272 |
1.14e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.09 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 620 KQNQELKEAEEKLRSTNQDLCNQMRqmvqefdhdKQEAVARCERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQ 699
Cdd:PTZ00121 1170 RKAEDAKKAEAARKAEEVRKAEELR---------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 700 SQLRSDLDKMNKEMAAVQECYLE--VCREKDGLESTLRKTME-KAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQ 776
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAhfARRQAAIKAEEARKADElKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 777 SWLQEQAAGATQQAEK--ESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAVLAEEQARQV 854
Cdd:PTZ00121 1321 KKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA 1400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 855 QQEK----ELATKEALRKPEVELELKYCEIiaQKVETAVQNAR-SRWIQELPMLAEYKallRAQQQEWAKQQELAVAHRL 929
Cdd:PTZ00121 1401 EEDKkkadELKKAAAAKKKADEAKKKAEEK--KKADEAKKKAEeAKKADEAKKKAEEA---KKAEEAKKKAEEAKKADEA 1475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 930 SLALSEAK--EKWKSELENMKPNVMSVKELEE---KVHSLQKELELKDEEVpvIVRAEVAKARTEWNK----------EK 994
Cdd:PTZ00121 1476 KKKAEEAKkaDEAKKKAEEAKKKADEAKKAAEakkKADEAKKAEEAKKADE--AKKAEEAKKADEAKKaeekkkadelKK 1553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 995 QEEIHKIQEQNEEDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRKEwtlQEAQQTQVEIRQYEE 1074
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEE 1630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1075 DTltvlayllKDTQLEYGGDSQDKQLLEAMSACSSKWISVQYFEKVKACIQKALHDMLSlltdsvASEQEKRKvvksSAD 1154
Cdd:PTZ00121 1631 EK--------KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK------KAEEDEKK----AAE 1692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1155 TVSWTSSEGDSAVPVPLPDSTSVRCAQSSAwlKAEAETDKKICEIKglrcghcfQELEKEKQECQDLRRKlEKCRRHLQH 1234
Cdd:PTZ00121 1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELK--KAEEENKIKAEEAK--------KEAEEDKKKAEEAKKD-EEEKKKIAH 1761
|
650 660 670
....*....|....*....|....*....|....*...
gi 124487356 1235 LERTHRAAVEKLGEENSRVVEELIEENhDMKNKLEALR 1272
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEEELDEE-DEKRRMEVDK 1798
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
236-812 |
3.81e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.08 E-value: 3.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 236 KAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKL 315
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 316 TKKLRTTEITLESLKQQLVELHHS-----ESLQRAREHHESIVASLTQKHEEQVSSLQKNLDAT----------ITALQE 380
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAEElaeleEKLEELKEELESLEAELEELEAELEELESRLEELEeqletlrskvAQLELQ 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 381 QESI---CTRLKDHVQQLERNQEAVRLEKTELINRLTRS-LEDSQKQCAHL--LQSGSVQEVAQLQLQLQQAQKAHVLSE 454
Cdd:TIGR02168 395 IASLnneIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELeeELEELQEELERLEEALEELREELEEAE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 455 SMNKALQEELTELKDEI-----------SLYESAAEL--------GVLPG-------DSEGDLSIE--LTESCVDLGIKK 506
Cdd:TIGR02168 475 QALDAAERELAQLQARLdslerlqenleGFSEGVKALlknqsglsGILGVlselisvDEGYEAAIEaaLGGRLQAVVVEN 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 507 VNW--------KQSKANRVT----QQESPDEDPSKDELILKLKTQVQRLLtSNSVKR---------------HLVSQLQS 559
Cdd:TIGR02168 555 LNAakkaiaflKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVA-KDLVKFdpklrkalsyllggvLVVDDLDN 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 560 DLRECRETMEAFQQ-SKDGD--------SGMETKTDTSEKTTKQLWLESSEAINR--EDILQLKNEVQVLQKQNQELKEA 628
Cdd:TIGR02168 634 ALELAKKLRPGYRIvTLDGDlvrpggviTGGSAKTNSSILERRREIEELEEKIEEleEKIAELEKALAELRKELEELEEE 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 629 EEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQQHHE-AMKAQIRESLLAKHAVEKQHLLEVYEGTQ-------- 699
Cdd:TIGR02168 714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKElTELEAEIEELEERLEEAEEELAEAEAEIEeleaqieq 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 700 -----SQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTL---RKTMEKAQEQKRQLLEAREEYvrKLKLELEEKYQETL 771
Cdd:TIGR02168 794 lkeelKALREALDELRAELTLLNEEAANLRERLESLERRIaatERRLEDLEEQIEELSEDIESL--AAEIEELEELIEEL 871
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 124487356 772 KTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLDD 812
Cdd:TIGR02168 872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
596-1097 |
4.13e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 4.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 596 WLESSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFdHDKQEAVARCERTyQQHHEAMKAQ 675
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQD-IARLEERRRE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 676 IRESL---------LAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKR 746
Cdd:COG1196 314 LEERLeeleeelaeLEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 747 QLLEAREEYVRKLK-----LELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEwQSKLDDSLAAWRKTT 821
Cdd:COG1196 394 AAAELAAQLEELEEaeealLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE-EEALLELLAELLEEA 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 822 SDRGSQTEQVACPAAVSKAEAAAVLAEEQARQVQQEKELATKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELP 901
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 902 MLAEYKAllrAQQQEWAKQQELAVAHRLSLALSEAKEKWKSELENMKPNVMSV------KELEEKVHSLQKELELKDEEV 975
Cdd:COG1196 553 VEDDEVA---AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlvasdlREADARYYVLGDTLLGRTLVA 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 976 PVIVRAEVAKARTEWNKEKQEEIHKIQEQNEEDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRK 1055
Cdd:COG1196 630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 124487356 1056 EWTLQEAQQTQVEIRQYEEDTLTVLAYLLKDTQLEYGGDSQD 1097
Cdd:COG1196 710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
236-812 |
1.85e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.03 E-value: 1.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 236 KAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKL 315
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 316 TKKLRTTEITLESLKQQLVELhhSESLQRAREHHESIVASLTQKhEEQVSSLQKNLDATITALQEQESictRLKDHVQQL 395
Cdd:COG1196 301 EQDIARLEERRRELEERLEEL--EEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEE---ALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 396 ERNQEAVRLEKTELINRLTRSLEDSQKQcAHLLQSGSVQEVAQLQLQLQQAQKAHVLSESMNKALQEELTELKDEISLYE 475
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQL-EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 476 SAAEL-GVLPGDSEGDLSIELTESCVDLGIKKVNWKQSKANRVTQQESPDEDPSKDELILKLKTQVQRLLtsnsvkrHLV 554
Cdd:COG1196 454 LEEEEeALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-------GAV 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 555 SQLQSDLRECRETMEAFqqskDGDSGMETKTDTSEKTTKQLWLESSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRS 634
Cdd:COG1196 527 AVLIGVEAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 635 TNQDLcnqmRQMVQEFDHDKQEAVArcERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMA 714
Cdd:COG1196 603 LVASD----LREADARYYVLGDTLL--GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 715 AVQECyLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKES 794
Cdd:COG1196 677 AEAEL-EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755
|
570
....*....|....*...
gi 124487356 795 RQKLIQqlEKEWQSKLDD 812
Cdd:COG1196 756 LPEPPD--LEELERELER 771
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
308-1068 |
3.40e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 3.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 308 FRVSEEKLTKKLRTTEITLE-------SLKQQLVELH-HSESLQRARE--------HHESIVASLTQKHEE------QVS 365
Cdd:TIGR02168 170 YKERRKETERKLERTRENLDrledilnELERQLKSLErQAEKAERYKElkaelrelELALLVLRLEELREEleelqeELK 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 366 SLQKNLDATITALQEQESICTRLKDHVQQLERNQEAVR---LEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLq 442
Cdd:TIGR02168 250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL- 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 443 lqqaqkahvlsESMNKALQEELTELKDEISlyesaaelgvlpgdsegdlsiELTESCVDLGIKKVNWKQSKANRVTQQEs 522
Cdd:TIGR02168 329 -----------ESKLDELAEELAELEEKLE---------------------ELKEELESLEAELEELEAELEELESRLE- 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 523 pdedpSKDELILKLKTQVQRLltsnsvkRHLVSQLQSDLRECRETMEAFQQSKDGD----SGMETKTDTSEKTTKQLWLE 598
Cdd:TIGR02168 376 -----ELEEQLETLRSKVAQL-------ELQIASLNNEIERLEARLERLEDRRERLqqeiEELLKKLEEAELKELQAELE 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 599 SSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDL------CNQMRQMVQEFDhDKQEAVA------------- 659
Cdd:TIGR02168 444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqarLDSLERLQENLE-GFSEGVKallknqsglsgil 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 660 -------RCERTYQQhheAMKAQIRESL-----------------LAKHAVEKQHLLEVYEGTQSQLRSDldkmNKEMAA 715
Cdd:TIGR02168 523 gvlseliSVDEGYEA---AIEAALGGRLqavvvenlnaakkaiafLKQNELGRVTFLPLDSIKGTEIQGN----DREILK 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 716 VQECYLEVCREKDGLESTLRKTME-------------KAQEQKRQlLEAREEYV-----------------RKLKLELEE 765
Cdd:TIGR02168 596 NIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldNALELAKK-LRPGYRIVtldgdlvrpggvitggsAKTNSSILE 674
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 766 KYQETLKTERQSWLQEQAAGATQQAEKESRQKLiQQLEKEwqskLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAV 845
Cdd:TIGR02168 675 RRREIEELEEKIEELEEKIAELEKALAELRKEL-EELEEE----LEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 846 LAEEQARQVQQEKElaTKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALL-----RAQQQEWAKQ 920
Cdd:TIGR02168 750 AQLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllneEAANLRERLE 827
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 921 QELAVAHRLSLALSEAKEKWKSELENMKPNVMSVKELEEKVHSLQKELELKDEEvpvivRAEVAKARTEWNKEKQEEIHK 1000
Cdd:TIGR02168 828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE-----RASLEEALALLRSELEELSEE 902
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124487356 1001 IQEQNE-----EDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRKEWTLQEAQQTQVE 1068
Cdd:TIGR02168 903 LRELESkrselRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
228-1046 |
5.52e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.98 E-value: 5.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 228 IIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIaalEAQVEA 307
Cdd:pfam02463 196 KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEK---LAQVLK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 308 FRVSEEKLTKKLRTTEITLESLKQQLVElhHSESLQRAREHHESIVasltQKHEEQVSSLQKNLDATITALQEQESICTR 387
Cdd:pfam02463 273 ENKEEEKEKKLQEEELKLLAKEEEELKS--ELLKLERRKVDDEEKL----KESEKEKKKAEKELKKEKEEIEELEKELKE 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 388 LKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQLQQA--QKAHVLSESMNKALQEELT 465
Cdd:pfam02463 347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKeaQLLLELARQLEDLLKEEKK 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 466 ELKDEISLYESAAELGVLPgdsegdlSIELTESCVDLGIKKVNWKQSKANRVTQQESPDEDPSKDELILKLKTQVQRLLT 545
Cdd:pfam02463 427 EELEILEEEEESIELKQGK-------LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 546 SNsvkrhlvsqlqsdLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWLESSEAINREDILQLKNEVQVLQKQNQEL 625
Cdd:pfam02463 500 QK-------------ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 626 KEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSD 705
Cdd:pfam02463 567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 706 LDKMNKEmaaVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQaag 785
Cdd:pfam02463 647 GLRKGVS---LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE--- 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 786 ATQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACpaavskaeAAAVLAEEQARQVQQEKELATKEA 865
Cdd:pfam02463 721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSE--------LSLKEKELAEEREKTEKLKVEEEK 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 866 LRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQELAVAHRLSLALSEAKEKWKSELE 945
Cdd:pfam02463 793 EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQEL 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 946 NMKPNVMSVKELEEKVHSLQKELELKDEEVPVIVRAEVAKARTEWNKEKQEEIHKIQEQNEEDYRQFLEDHrNKINEVLA 1025
Cdd:pfam02463 873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLE-EADEKEKE 951
|
810 820
....*....|....*....|.
gi 124487356 1026 AAKEDFVKQKAELLLQKETEF 1046
Cdd:pfam02463 952 ENNKEEEEERNKRLLLAKEEL 972
|
|
| LCD1 |
pfam09798 |
DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. ... |
230-345 |
3.97e-04 |
|
DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. In Schizosaccharomyces pombe this protein is called Rad26 and in Saccharomyces cerevisiae it is called LCD1.
Pssm-ID: 462906 Cd Length: 615 Bit Score: 45.00 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 230 QLQVLNKAKERQLDSL---VEKLKDS-ERQVRYLSHQLLIVQDEKDGLalsLRESQQLFqngkeremqlEAQIAALEAQV 305
Cdd:pfam09798 5 KLELLQQEKEKELEKLknsYEELKSShEEELEKLKQEVQKLEDEKKFL---LNELRSLS----------ATSPASSQSHE 71
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 124487356 306 EAFRVSEEKLTKKLRTTEITLESLKQQLVELHHSESLQRA 345
Cdd:pfam09798 72 TDTDDSSSVSLKKRKIEESTAESLKQKYIRLQNNRIVDET 111
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
610-803 |
1.68e-03 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.56 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 610 QLKNEVQVLQKQNQElkEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARcertYQQHHEAMKAQIRES----LLAKHA 685
Cdd:cd16269 98 QLEEKKEEFCKQNEE--ASSKRCQALLQELSAPLEEKISQGSYSVPGGYQL----YLEDREKLVEKYRQVprkgVKAEEV 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 686 VekQHLLEVYEGT-QSQLRSD--LDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLlearEEYVRKLKLE 762
Cdd:cd16269 172 L--QEFLQSKEAEaEAILQADqaLTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQKLEDQERSY----EEHLRQLKEK 245
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 124487356 763 LEEKYQETLKTERQ---SWLQEQAAGATQQAEKESR--QKLIQQLE 803
Cdd:cd16269 246 MEEERENLLKEQERaleSKLKEQEALLEEGFKEQAEllQEEIRSLK 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
620-1272 |
1.14e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.09 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 620 KQNQELKEAEEKLRSTNQDLCNQMRqmvqefdhdKQEAVARCERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQ 699
Cdd:PTZ00121 1170 RKAEDAKKAEAARKAEEVRKAEELR---------KAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 700 SQLRSDLDKMNKEMAAVQECYLE--VCREKDGLESTLRKTME-KAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQ 776
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAhfARRQAAIKAEEARKADElKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 777 SWLQEQAAGATQQAEK--ESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAVLAEEQARQV 854
Cdd:PTZ00121 1321 KKKAEEAKKKADAAKKkaEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA 1400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 855 QQEK----ELATKEALRKPEVELELKYCEIiaQKVETAVQNAR-SRWIQELPMLAEYKallRAQQQEWAKQQELAVAHRL 929
Cdd:PTZ00121 1401 EEDKkkadELKKAAAAKKKADEAKKKAEEK--KKADEAKKKAEeAKKADEAKKKAEEA---KKAEEAKKKAEEAKKADEA 1475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 930 SLALSEAK--EKWKSELENMKPNVMSVKELEE---KVHSLQKELELKDEEVpvIVRAEVAKARTEWNK----------EK 994
Cdd:PTZ00121 1476 KKKAEEAKkaDEAKKKAEEAKKKADEAKKAAEakkKADEAKKAEEAKKADE--AKKAEEAKKADEAKKaeekkkadelKK 1553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 995 QEEIHKIQEQNEEDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRKEwtlQEAQQTQVEIRQYEE 1074
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEE 1630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1075 DTltvlayllKDTQLEYGGDSQDKQLLEAMSACSSKWISVQYFEKVKACIQKALHDMLSlltdsvASEQEKRKvvksSAD 1154
Cdd:PTZ00121 1631 EK--------KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK------KAEEDEKK----AAE 1692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1155 TVSWTSSEGDSAVPVPLPDSTSVRCAQSSAwlKAEAETDKKICEIKglrcghcfQELEKEKQECQDLRRKlEKCRRHLQH 1234
Cdd:PTZ00121 1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELK--KAEEENKIKAEEAK--------KEAEEDKKKAEEAKKD-EEEKKKIAH 1761
|
650 660 670
....*....|....*....|....*....|....*...
gi 124487356 1235 LERTHRAAVEKLGEENSRVVEELIEENhDMKNKLEALR 1272
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEEELDEE-DEKRRMEVDK 1798
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
588-1075 |
2.45e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 65.93 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 588 SEKTTKQLWLESSEAINREDILQLKNEVQvlqKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQQ 667
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEA---KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAA 1362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 668 HHEAMKAQIRESLLAKHAVE-KQHLLEVYEGTQSQLRSDLDKMNKEMAAVQEcylevcREKDGLESTLRKTME--KAQEQ 744
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKKKADAaKKKAEEKKKADEAKKKAEEDKKKADELKKAA------AAKKKADEAKKKAEEkkKADEA 1436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 745 KRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDR 824
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAK 1516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 825 GSQTEQVAcPAAVSKAEAAAVLAEEQARQVQQEKELATKEALRKPEvelELKYCEiiAQKVETAVQNARSRWIQELPMLA 904
Cdd:PTZ00121 1517 KAEEAKKA-DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAE---EKKKAE--EAKKAEEDKNMALRKAEEAKKAE 1590
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 905 EYKALLRAQQQEWAKQQELAVAHRLSLALSEAKEKWKSELENMKPNVMSVKELEEKvhslQKELELKDEEVPVIVRAEVA 984
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEK----KKAEELKKAEEENKIKAAEE 1666
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 985 KARTEWNKEKQEEIHKiqeqNEEDYRQFLEDHRNKINEvlaaakedfvKQKAELLLQKETEFQACLDQSRKEWTLQEAQQ 1064
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKK----AEEDEKKAAEALKKEAEE----------AKKAEELKKKEAEEKKKAEELKKAEEENKIKA 1732
|
490
....*....|.
gi 124487356 1065 TQVEiRQYEED 1075
Cdd:PTZ00121 1733 EEAK-KEAEED 1742
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
236-812 |
3.81e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.08 E-value: 3.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 236 KAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKL 315
Cdd:TIGR02168 235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 316 TKKLRTTEITLESLKQQLVELHHS-----ESLQRAREHHESIVASLTQKHEEQVSSLQKNLDAT----------ITALQE 380
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAEElaeleEKLEELKEELESLEAELEELEAELEELESRLEELEeqletlrskvAQLELQ 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 381 QESI---CTRLKDHVQQLERNQEAVRLEKTELINRLTRS-LEDSQKQCAHL--LQSGSVQEVAQLQLQLQQAQKAHVLSE 454
Cdd:TIGR02168 395 IASLnneIERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELeeELEELQEELERLEEALEELREELEEAE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 455 SMNKALQEELTELKDEI-----------SLYESAAEL--------GVLPG-------DSEGDLSIE--LTESCVDLGIKK 506
Cdd:TIGR02168 475 QALDAAERELAQLQARLdslerlqenleGFSEGVKALlknqsglsGILGVlselisvDEGYEAAIEaaLGGRLQAVVVEN 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 507 VNW--------KQSKANRVT----QQESPDEDPSKDELILKLKTQVQRLLtSNSVKR---------------HLVSQLQS 559
Cdd:TIGR02168 555 LNAakkaiaflKQNELGRVTflplDSIKGTEIQGNDREILKNIEGFLGVA-KDLVKFdpklrkalsyllggvLVVDDLDN 633
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 560 DLRECRETMEAFQQ-SKDGD--------SGMETKTDTSEKTTKQLWLESSEAINR--EDILQLKNEVQVLQKQNQELKEA 628
Cdd:TIGR02168 634 ALELAKKLRPGYRIvTLDGDlvrpggviTGGSAKTNSSILERRREIEELEEKIEEleEKIAELEKALAELRKELEELEEE 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 629 EEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQQHHE-AMKAQIRESLLAKHAVEKQHLLEVYEGTQ-------- 699
Cdd:TIGR02168 714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKElTELEAEIEELEERLEEAEEELAEAEAEIEeleaqieq 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 700 -----SQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTL---RKTMEKAQEQKRQLLEAREEYvrKLKLELEEKYQETL 771
Cdd:TIGR02168 794 lkeelKALREALDELRAELTLLNEEAANLRERLESLERRIaatERRLEDLEEQIEELSEDIESL--AAEIEELEELIEEL 871
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 124487356 772 KTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLDD 812
Cdd:TIGR02168 872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
596-1097 |
4.13e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.96 E-value: 4.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 596 WLESSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFdHDKQEAVARCERTyQQHHEAMKAQ 675
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQD-IARLEERRRE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 676 IRESL---------LAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKR 746
Cdd:COG1196 314 LEERLeeleeelaeLEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 747 QLLEAREEYVRKLK-----LELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEwQSKLDDSLAAWRKTT 821
Cdd:COG1196 394 AAAELAAQLEELEEaeealLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE-EEALLELLAELLEEA 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 822 SDRGSQTEQVACPAAVSKAEAAAVLAEEQARQVQQEKELATKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELP 901
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 902 MLAEYKAllrAQQQEWAKQQELAVAHRLSLALSEAKEKWKSELENMKPNVMSV------KELEEKVHSLQKELELKDEEV 975
Cdd:COG1196 553 VEDDEVA---AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDlvasdlREADARYYVLGDTLLGRTLVA 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 976 PVIVRAEVAKARTEWNKEKQEEIHKIQEQNEEDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRK 1055
Cdd:COG1196 630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 124487356 1056 EWTLQEAQQTQVEIRQYEEDTLTVLAYLLKDTQLEYGGDSQD 1097
Cdd:COG1196 710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
236-812 |
1.85e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.03 E-value: 1.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 236 KAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKL 315
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 316 TKKLRTTEITLESLKQQLVELhhSESLQRAREHHESIVASLTQKhEEQVSSLQKNLDATITALQEQESictRLKDHVQQL 395
Cdd:COG1196 301 EQDIARLEERRRELEERLEEL--EEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEE---ALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 396 ERNQEAVRLEKTELINRLTRSLEDSQKQcAHLLQSGSVQEVAQLQLQLQQAQKAHVLSESMNKALQEELTELKDEISLYE 475
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQL-EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 476 SAAEL-GVLPGDSEGDLSIELTESCVDLGIKKVNWKQSKANRVTQQESPDEDPSKDELILKLKTQVQRLLtsnsvkrHLV 554
Cdd:COG1196 454 LEEEEeALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-------GAV 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 555 SQLQSDLRECRETMEAFqqskDGDSGMETKTDTSEKTTKQLWLESSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRS 634
Cdd:COG1196 527 AVLIGVEAAYEAALEAA----LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVD 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 635 TNQDLcnqmRQMVQEFDHDKQEAVArcERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMA 714
Cdd:COG1196 603 LVASD----LREADARYYVLGDTLL--GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 715 AVQECyLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKES 794
Cdd:COG1196 677 AEAEL-EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755
|
570
....*....|....*...
gi 124487356 795 RQKLIQqlEKEWQSKLDD 812
Cdd:COG1196 756 LPEPPD--LEELERELER 771
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
308-1068 |
3.40e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.91 E-value: 3.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 308 FRVSEEKLTKKLRTTEITLE-------SLKQQLVELH-HSESLQRARE--------HHESIVASLTQKHEE------QVS 365
Cdd:TIGR02168 170 YKERRKETERKLERTRENLDrledilnELERQLKSLErQAEKAERYKElkaelrelELALLVLRLEELREEleelqeELK 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 366 SLQKNLDATITALQEQESICTRLKDHVQQLERNQEAVR---LEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLq 442
Cdd:TIGR02168 250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQkelYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL- 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 443 lqqaqkahvlsESMNKALQEELTELKDEISlyesaaelgvlpgdsegdlsiELTESCVDLGIKKVNWKQSKANRVTQQEs 522
Cdd:TIGR02168 329 -----------ESKLDELAEELAELEEKLE---------------------ELKEELESLEAELEELEAELEELESRLE- 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 523 pdedpSKDELILKLKTQVQRLltsnsvkRHLVSQLQSDLRECRETMEAFQQSKDGD----SGMETKTDTSEKTTKQLWLE 598
Cdd:TIGR02168 376 -----ELEEQLETLRSKVAQL-------ELQIASLNNEIERLEARLERLEDRRERLqqeiEELLKKLEEAELKELQAELE 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 599 SSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDL------CNQMRQMVQEFDhDKQEAVA------------- 659
Cdd:TIGR02168 444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqarLDSLERLQENLE-GFSEGVKallknqsglsgil 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 660 -------RCERTYQQhheAMKAQIRESL-----------------LAKHAVEKQHLLEVYEGTQSQLRSDldkmNKEMAA 715
Cdd:TIGR02168 523 gvlseliSVDEGYEA---AIEAALGGRLqavvvenlnaakkaiafLKQNELGRVTFLPLDSIKGTEIQGN----DREILK 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 716 VQECYLEVCREKDGLESTLRKTME-------------KAQEQKRQlLEAREEYV-----------------RKLKLELEE 765
Cdd:TIGR02168 596 NIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldNALELAKK-LRPGYRIVtldgdlvrpggvitggsAKTNSSILE 674
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 766 KYQETLKTERQSWLQEQAAGATQQAEKESRQKLiQQLEKEwqskLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAV 845
Cdd:TIGR02168 675 RRREIEELEEKIEELEEKIAELEKALAELRKEL-EELEEE----LEQLRKELEELSRQISALRKDLARLEAEVEQLEERI 749
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 846 LAEEQARQVQQEKElaTKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALL-----RAQQQEWAKQ 920
Cdd:TIGR02168 750 AQLSKELTELEAEI--EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllneEAANLRERLE 827
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 921 QELAVAHRLSLALSEAKEKWKSELENMKPNVMSVKELEEKVHSLQKELELKDEEvpvivRAEVAKARTEWNKEKQEEIHK 1000
Cdd:TIGR02168 828 SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE-----RASLEEALALLRSELEELSEE 902
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124487356 1001 IQEQNE-----EDYRQFLEDHRNKINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRKEWTLQEAQQTQVE 1068
Cdd:TIGR02168 903 LRELESkrselRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
626-938 |
3.69e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.41 E-value: 3.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 626 KEAEEKLRSTNQ------DLCNQMRQMV------------------QEFDHDKQEAVARcERTYQQHHEAMKAQIREslL 681
Cdd:COG1196 175 EEAERKLEATEEnlerleDILGELERQLeplerqaekaeryrelkeELKELEAELLLLK-LRELEAELEELEAELEE--L 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 682 AKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKL-K 760
Cdd:COG1196 252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEeE 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 761 LELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVAcpaaVSKA 840
Cdd:COG1196 332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE----ELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 841 EAAAVLAEEQARQVQQEKELATKEALRKPEVELELKYCEIIAQKVETAVQNARsrwiQELPMLAEYKALLRAQQQEWAKQ 920
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA----LLELLAELLEEAALLEAALAELL 483
|
330
....*....|....*...
gi 124487356 921 QELAVAHRLSLALSEAKE 938
Cdd:COG1196 484 EELAEAAARLLLLLEAEA 501
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
293-969 |
4.97e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.02 E-value: 4.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 293 QLEAQIAALEAQVEAfrvseeklTKKLRTteitlesLKQQLVELHHSESLQRAREHHESIvasltQKHEEQVSSLQKNLD 372
Cdd:COG1196 197 ELERQLEPLERQAEK--------AERYRE-------LKEELKELEAELLLLKLRELEAEL-----EELEAELEELEAELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 373 ATITALQEQESICTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEvaqlqlqlqqaqkahvl 452
Cdd:COG1196 257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE----------------- 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 453 sesmnkALQEELTELKDEISLYESAAElgvlpgdsegDLSIELTESCVDLGIKKVNWKQSKANRVTQQESPDEdpsKDEL 532
Cdd:COG1196 320 ------ELEEELAELEEELEELEEELE----------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE---AEEE 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 533 ILKLKTQVQRLLTSNSVKRHLVSQLQSDLRECRETMEAFQQSKDGdsgmetktdtsekttkqlwLESSEAINREDILQLK 612
Cdd:COG1196 381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE-------------------LEEALAELEEEEEEEE 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 613 NEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARcertyQQHHEAMKAQIRESLLAKHAVEKQHLL 692
Cdd:COG1196 442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA-----AARLLLLLEAEADYEGFLEGVKAALLL 516
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 693 EVYEGTQSQLrSDLDKMNKEMAAVQECYLEVcrekdGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLK 772
Cdd:COG1196 517 AGLRGLAGAV-AVLIGVEAAYEAALEAALAA-----ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 773 TERQSWLQEQAAG-ATQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEqvacpaavsKAEAAAVLAEEQA 851
Cdd:COG1196 591 ALARGAIGAAVDLvASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE---------VTLEGEGGSAGGS 661
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 852 RQVQQEKELATKEALRKPEVELELKycEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQELAVAHRLSL 931
Cdd:COG1196 662 LTGGSRRELLAALLEAEAELEELAE--RLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739
|
650 660 670
....*....|....*....|....*....|....*...
gi 124487356 932 ALSEAKEKWKSELENMKPNVMSVKELEEKVHSLQKELE 969
Cdd:COG1196 740 ELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
554-1078 |
5.45e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 58.23 E-value: 5.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 554 VSQLQSDLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWLESSEAINREDILQLKNEvqvlQKQNQELKEAEEKLR 633
Cdd:PTZ00121 1304 ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE----KAEAAEKKKEEAKKK 1379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 634 StnqdlcnqmrqmvqEFDHDKQEAVARCERTYQQHHEAMKaqiRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEM 713
Cdd:PTZ00121 1380 A--------------DAAKKKAEEKKKADEAKKKAEEDKK---KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEE 1442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 714 AAVQECYLEVCREKDGLESTLRKTME--KAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTerqswlQEQAAGATQQAE 791
Cdd:PTZ00121 1443 AKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK------AAEAKKKADEAK 1516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 792 KESRQKLIQQLEK-EWQSKLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAVLAEEQARQVQQEKELATKEALRKPE 870
Cdd:PTZ00121 1517 KAEEAKKADEAKKaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEE 1596
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 871 VELelKYCEIIAQKVETAVQNARSRWIQELPMLAE-----YKALLRAQQQEWAKQQELAVAHRLSlALSEAKEKWKSELE 945
Cdd:PTZ00121 1597 VMK--LYEEEKKMKAEEAKKAEEAKIKAEELKKAEeekkkVEQLKKKEAEEKKKAEELKKAEEEN-KIKAAEEAKKAEED 1673
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 946 NMKPNvmSVKELEEKVHSLQKELELKDEEVPvivRAEVAKARTEWNKEKQEEIHKIQEQNE---EDYRQFLEDHRNKINE 1022
Cdd:PTZ00121 1674 KKKAE--EAKKAEEDEKKAAEALKKEAEEAK---KAEELKKKEAEEKKKAEELKKAEEENKikaEEAKKEAEEDKKKAEE 1748
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 124487356 1023 vlaaAKEDFVKQKAELLLQKETEFQACLDQSRKEWTLQEAQQTQVEIRQYEEDTLT 1078
Cdd:PTZ00121 1749 ----AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI 1800
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
207-765 |
1.17e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 207 FEGLQQQFLGANETDSAENIHIIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQlfQN 286
Cdd:TIGR02168 346 LEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQ--EI 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 287 GKEREMQLEAQIAALEAQVEAFRVSEEKLTKKLRTTEITLESLKQQLVELHHSESLQRAREHHESIVASLTQKHEEQVSS 366
Cdd:TIGR02168 424 EELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 367 LQKNLDATITALQEQESICTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQLQQA 446
Cdd:TIGR02168 504 FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKG 583
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 447 QKAHVLSESMNKALQEELTELKDEISlYESAAELGVLP----------GDSEGDLSIELT--ESCVDLGIKKVNWK---- 510
Cdd:TIGR02168 584 TEIQGNDREILKNIEGFLGVAKDLVK-FDPKLRKALSYllggvlvvddLDNALELAKKLRpgYRIVTLDGDLVRPGgvit 662
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 511 ---QSKANRVTQQESPDEDPSKD-----ELILKLKTQVQRLLTSNSVKRHLVSQLQSDLRECRetmeafQQSKDGDSGME 582
Cdd:TIGR02168 663 ggsAKTNSSILERRREIEELEEKieeleEKIAELEKALAELRKELEELEEELEQLRKELEELS------RQISALRKDLA 736
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 583 TKTDTSEKTTKQLWLESSEAINREDilQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQ-------------- 648
Cdd:TIGR02168 737 RLEAEVEQLEERIAQLSKELTELEA--EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlrealdelraeltl 814
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 649 --EFDHDKQEAVARCERTY---QQHHEAMKAQIREslLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEV 723
Cdd:TIGR02168 815 lnEEAANLRERLESLERRIaatERRLEDLEEQIEE--LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALL 892
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 124487356 724 CREKDGLESTLRKTMEKAQEQKRQLLEAREEyVRKLKLELEE 765
Cdd:TIGR02168 893 RSELEELSEELRELESKRSELRRELEELREK-LAQLELRLEG 933
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
278-795 |
1.47e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.31 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 278 RESQQLF-QNGKEREM------QLEAQIAALEAQVEAFRVSEEKL---TKKLRTTEITLESLKQQLVELHHSESLQRARE 347
Cdd:COG4717 53 KEADELFkPQGRKPELnlkelkELEEELKEAEEKEEEYAELQEELeelEEELEELEAELEELREELEKLEKLLQLLPLYQ 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 348 HHESIVASLTQKhEEQVSSLQKNLDATITALQEQESICTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHL 427
Cdd:COG4717 133 ELEALEAELAEL-PERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAEL 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 428 LQS-GSVQEVAQLQLQLQQAQKAHVLSESMNKALQEELTELKDEISLYESAAELGVLPGDSEGDLSIELTESCVDLGIKK 506
Cdd:COG4717 212 EEElEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFL 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 507 VNWKQSKANRVTQQESPDEDPSKDELILKLKTQVQRLLTSNSVKRHLVSQLQSDLRECRETMEAFQQSKDgdsgmETKTD 586
Cdd:COG4717 292 LLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE-----ELQLE 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 587 TSEKTTKQLwLESSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQ 666
Cdd:COG4717 367 ELEQEIAAL-LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELE 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 667 QHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQecylevcrekdGLESTLRKTMEKAQEQKR 746
Cdd:COG4717 446 EELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALK-----------LALELLEEAREEYREERL 514
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 124487356 747 -QLLEAREEYVRKLkleLEEKYQETLKTERQSWLQEQAAGATQQAEKESR 795
Cdd:COG4717 515 pPVLERASEYFSRL---TDGRYRLIRIDEDLSLKVDTEDGRTRPVEELSR 561
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
288-805 |
4.44e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 288 KEREMQLEAQIAALEaqVEAFRVSEEKLTKKLRTTEITLESLKQQLVELHhsESLQRAREHHESIvasltqkhEEQVSSL 367
Cdd:COG1196 219 KEELKELEAELLLLK--LRELEAELEELEAELEELEAELEELEAELAELE--AELEELRLELEEL--------ELELEEA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 368 QKNLDATITALQEQESIctrlKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQLQQAQ 447
Cdd:COG1196 287 QAEEYELLAELARLEQD----IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 448 KAHVLSESMNKALQEELTELKDEISLYESAAELgvlpgDSEGDLSIELTESCVDLGIKKVNWKQSKANRVTQQEspDEDP 527
Cdd:COG1196 363 AEEALLEAEAELAEAEEELEELAEELLEALRAA-----AELAAQLEELEEAEEALLERLERLEEELEELEEALA--ELEE 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 528 SKDELILKLKTQVQRLLTSNSVKRHLVSQLQSDLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWLESSEAINRED 607
Cdd:COG1196 436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 608 ILQLKNEVQVLQKQNQELKEAEEKLRST-----NQDLCNQMRQMVQEFDHDKQEAVARCER-------------TYQQHH 669
Cdd:COG1196 516 LAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalQNIVVEDDEVAAAAIEYLKAAKAGRATFlpldkiraraalaAALARG 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 670 EAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLL 749
Cdd:COG1196 596 AIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 124487356 750 EAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKE 805
Cdd:COG1196 676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
228-1046 |
5.52e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.98 E-value: 5.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 228 IIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIaalEAQVEA 307
Cdd:pfam02463 196 KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEK---LAQVLK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 308 FRVSEEKLTKKLRTTEITLESLKQQLVElhHSESLQRAREHHESIVasltQKHEEQVSSLQKNLDATITALQEQESICTR 387
Cdd:pfam02463 273 ENKEEEKEKKLQEEELKLLAKEEEELKS--ELLKLERRKVDDEEKL----KESEKEKKKAEKELKKEKEEIEELEKELKE 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 388 LKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQLQQA--QKAHVLSESMNKALQEELT 465
Cdd:pfam02463 347 LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKeaQLLLELARQLEDLLKEEKK 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 466 ELKDEISLYESAAELGVLPgdsegdlSIELTESCVDLGIKKVNWKQSKANRVTQQESPDEDPSKDELILKLKTQVQRLLT 545
Cdd:pfam02463 427 EELEILEEEEESIELKQGK-------LTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 546 SNsvkrhlvsqlqsdLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWLESSEAINREDILQLKNEVQVLQKQNQEL 625
Cdd:pfam02463 500 QK-------------ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 626 KEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTYQQHHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSD 705
Cdd:pfam02463 567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 706 LDKMNKEmaaVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQaag 785
Cdd:pfam02463 647 GLRKGVS---LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE--- 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 786 ATQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACpaavskaeAAAVLAEEQARQVQQEKELATKEA 865
Cdd:pfam02463 721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSE--------LSLKEKELAEEREKTEKLKVEEEK 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 866 LRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQELAVAHRLSLALSEAKEKWKSELE 945
Cdd:pfam02463 793 EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQEL 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 946 NMKPNVMSVKELEEKVHSLQKELELKDEEVPVIVRAEVAKARTEWNKEKQEEIHKIQEQNEEDYRQFLEDHrNKINEVLA 1025
Cdd:pfam02463 873 LLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLE-EADEKEKE 951
|
810 820
....*....|....*....|.
gi 124487356 1026 AAKEDFVKQKAELLLQKETEF 1046
Cdd:pfam02463 952 ENNKEEEEERNKRLLLAKEEL 972
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
700-1346 |
5.90e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 54.76 E-value: 5.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 700 SQLRSDLDKMNKEMAAvqecylEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERqswl 779
Cdd:PTZ00121 1075 SYKDFDFDAKEDNRAD------EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEE---- 1144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 780 qeqaagaTQQAEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVAcPAAVSKAEAAAVLAEEQARQVQQEKE 859
Cdd:PTZ00121 1145 -------ARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKA-EELRKAEDARKAEAARKAEEERKAEE 1216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 860 LATKEALRKPEvelELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQElavaHRLSLALSEAKEK 939
Cdd:PTZ00121 1217 ARKAEDAKKAE---AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE----ARKADELKKAEEK 1289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 940 WKSELENMKPNVMSVKELEEKVHSLQKELELKDEEVPVIVRAEVAKARTEWNKEKQE-----------EIHKIQEQNEED 1008
Cdd:PTZ00121 1290 KKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEaakaeaeaaadEAEAAEEKAEAA 1369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1009 YRQfLEDHRNKINEVLAAAKE----DFVKQKAELLLQKETEFQACLDQSRKEwtlQEAQQTQVEIRQYEEdtltvlayLL 1084
Cdd:PTZ00121 1370 EKK-KEEAKKKADAAKKKAEEkkkaDEAKKKAEEDKKKADELKKAAAAKKKA---DEAKKKAEEKKKADE--------AK 1437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1085 KDTQLEYGGDSQDKQLLEAMSACSSkwisvqyfeKVKACIQKALHDMLSLLTDSVASEQEKRKV--VKSSADTVSWTSSE 1162
Cdd:PTZ00121 1438 KKAEEAKKADEAKKKAEEAKKAEEA---------KKKAEEAKKADEAKKKAEEAKKADEAKKKAeeAKKKADEAKKAAEA 1508
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1163 GDSAVPVPLPDSTSVRCAQSSAWLKAEAETDKKICEIKGLRCGHCFQELEKEKQecqdlRRKLEKCRRHLQHLERTHRAA 1242
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEE-----KKKAEEAKKAEEDKNMALRKA 1583
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1243 VEKLGEENSRVVEELIEENHDMKNKLEALRALCRTPPRSLSAGAAESAgpscsRQALEELRGQYIKAVRKIKR------- 1315
Cdd:PTZ00121 1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE-----KKKVEQLKKKEAEEKKKAEElkkaeee 1658
|
650 660 670
....*....|....*....|....*....|.
gi 124487356 1316 DMLRYIQESKERAAEMVKAEVLRERQETARK 1346
Cdd:PTZ00121 1659 NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
236-781 |
6.11e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 54.64 E-value: 6.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 236 KAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEK-------DGLALSLRESQQLFQNGK---EREMQLEAQIAALEAQV 305
Cdd:TIGR04523 148 KKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKlniqkniDKIKNKLLKLELLLSNLKkkiQKNKSLESQISELKKQN 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 306 EAFRVSEEKLTKKLRTTEITLESLKQQLVELhhSESLQRAREHHESIVASLTQkHEEQVSSLQK---NLDATITAL--QE 380
Cdd:TIGR04523 228 NQLKDNIEKKQQEINEKTTEISNTQTQLNQL--KDEQNKIKKQLSEKQKELEQ-NNKKIKELEKqlnQLKSEISDLnnQK 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 381 QESICTRLKDHVQQLERNQEAVRLEKTE---LINRLTRSLEDSQKQCAHllqsgsvqevaqlqlqlqqaqkahvlSESMN 457
Cdd:TIGR04523 305 EQDWNKELKSELKNQEKKLEEIQNQISQnnkIISQLNEQISQLKKELTN--------------------------SESEN 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 458 KALQEELTELKDEISLYESAAElgvlpGDSEGDLSIELTESCVDLGIKKV-NWKQSKANRVTQQESPDEDPSKD-----E 531
Cdd:TIGR04523 359 SEKQRELEEKQNEIEKLKKENQ-----SYKQEIKNLESQINDLESKIQNQeKLNQQKDEQIKKLQQEKELLEKEierlkE 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 532 LILKLKTQVQRLLTSNSVKRHLVSQLQSDLRECRETMEAFQQSkdgdsgMETKTDTSEKTTKQLWLESSE--AINREDIl 609
Cdd:TIGR04523 434 TIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRS------INKIKQNLEQKQKELKSKEKElkKLNEEKK- 506
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 610 QLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQ----EAVARCERTYQQHHEAMKaQIRESLLAKHA 685
Cdd:TIGR04523 507 ELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelkkENLEKEIDEKNKEIEELK-QTQKSLKKKQE 585
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 686 vEKQHLLEVYEGTQSQLRSDL-------DKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLLEARE---EY 755
Cdd:TIGR04523 586 -EKQELIDQKEKEKKDLIKEIeekekkiSSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNkwpEI 664
|
570 580
....*....|....*....|....*.
gi 124487356 756 VRKLKlELEEKYQETLKTERQsWLQE 781
Cdd:TIGR04523 665 IKKIK-ESKTKIDDIIELMKD-WLKE 688
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
239-816 |
6.24e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.54 E-value: 6.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 239 ERQLDSLvEKLKDSERQVRYLSHQLLIVQDEKDglALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKLTKK 318
Cdd:COG4913 248 REQIELL-EPIRELAERYAAARERLAELEYLRA--ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREE 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 319 LRTTE--------ITLESLKQQLvelhhsESLQRAREHHESIVASLtqkhEEQVSSLQKNLDATITALQEQESictRLKD 390
Cdd:COG4913 325 LDELEaqirgnggDRLEQLEREI------ERLERELEERERRRARL----EALLAALGLPLPASAEEFAALRA---EAAA 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 391 HVQQLERNQEAVRLEKTELINR---LTRSLEDSQKQCAHLLQSGSVqevaqlqlqlqQAQKAHVLSESMNKALQE----- 462
Cdd:COG4913 392 LLEALEEELEALEEALAEAEAAlrdLRRELRELEAEIASLERRKSN-----------IPARLLALRDALAEALGLdeael 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 463 ----ELTELKDEISLYESAAElGVLPGDSegdLSIELTESCVDLGIKKVNWKQSKANRVTQQESPD------EDPSKDEL 532
Cdd:COG4913 461 pfvgELIEVRPEEERWRGAIE-RVLGGFA---LTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGlpdperPRLDPDSL 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 533 ILKLKTQvqrlltSNSVKRHLVSQLQSDL-RECRETMEAFQQSKDG--DSGMeTKT-------DTSEKTTKQLWLESS-- 600
Cdd:COG4913 537 AGKLDFK------PHPFRAWLEAELGRRFdYVCVDSPEELRRHPRAitRAGQ-VKGngtrhekDDRRRIRSRYVLGFDnr 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 601 EAIN--REDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLcnqmrQMVQEFDHDKQEaVARCERTYQQhHEAMKAQIRE 678
Cdd:COG4913 610 AKLAalEAELAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSWDEID-VASAEREIAE-LEAELERLDA 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 679 SLLAKHAVEKQhlLEVYEGTQSQLRSDLDKMNKEMAAVQECylevcrekdglestlRKTMEKAQEQKRQLLEAREEYVRK 758
Cdd:COG4913 683 SSDDLAALEEQ--LEELEAELEELEEELDELKGEIGRLEKE---------------LEQAEEELDELQDRLEAAEDLARL 745
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 124487356 759 -LKLELEEKYQETLKTERQS----WLQEQAAGATQQAEKESRQ--KLIQQLEKEWQ---SKLDDSLAA 816
Cdd:COG4913 746 eLRALLEERFAAALGDAVERelreNLEERIDALRARLNRAEEEleRAMRAFNREWPaetADLDADLES 813
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
510-1042 |
9.29e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 54.38 E-value: 9.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 510 KQSKANRVTQQESPDEDPSKDEL-ILKLKTQVQRLLTSNSVKRhlVSQLQSDLRECRETMEAFQQSK-DGDSGMETKTDT 587
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKK--ADAAKKKAEEKKKADEAKKKAEeDKKKADELKKAA 1414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 588 SEKTTKQLWLESSEAINREDilQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAvarcERTYQQ 667
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKAD--EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA----KKADEA 1488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 668 HHEAMKAQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLEST--LRKTMEKAQ-EQ 744
Cdd:PTZ00121 1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAeeLKKAEEKKKaEE 1568
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 745 KRQLLEAREEYVRKLklELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKL-IQQLEKEWQSKldDSLAAWRKTTSD 823
Cdd:PTZ00121 1569 AKKAEEDKNMALRKA--EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIkAEELKKAEEEK--KKVEQLKKKEAE 1644
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 824 RGSQTEQVacpaaVSKAEAAAVLAEEQARQVQQEKELAtkEALRKPEvELELKYCEIIAQKVETA--VQNARSRWIQELP 901
Cdd:PTZ00121 1645 EKKKAEEL-----KKAEEENKIKAAEEAKKAEEDKKKA--EEAKKAE-EDEKKAAEALKKEAEEAkkAEELKKKEAEEKK 1716
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 902 MLAEYKallRAQQQEWAKQQELavahrlslalseakeKWKSELENMKPNVMSVKELEE-KVHSLQKELELKDEEVPVIVR 980
Cdd:PTZ00121 1717 KAEELK---KAEEENKIKAEEA---------------KKEAEEDKKKAEEAKKDEEEKkKIAHLKKEEEKKAEEIRKEKE 1778
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124487356 981 AEVAKARTEWNKEKQEEIHKIQEQNEEDYRQFLEDHrNKINEVLAAAKEDFVKQKAELLLQK 1042
Cdd:PTZ00121 1779 AVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGG-KEGNLVINDSKEMEDSAIKEVADSK 1839
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
725-1393 |
2.72e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.67 E-value: 2.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 725 REKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLELEEK--------------YQETLKTERQSWLQEQAAGATQQ- 789
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKkaleyyqlkeklelEEEYLLYLDYLKLNEERIDLLQEl 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 790 -AEKESRQKLIQQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACPAAVSKAEAAAVLAEEQARQVQQEKELATKEALRK 868
Cdd:pfam02463 246 lRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 869 PEVELELKYCEIIAQKVETAVQNarsrwIQELPMLAEYKALLRAQQQEWAKQQELAVAHRL--SLALSEAKEKWK--SEL 944
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELKELE-----IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLesERLSSAAKLKEEelELK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 945 ENMKPNVMSVKELEEKV----HSLQKELELKDEEVPVIVRAEVAKARTEWNKEKQEEIHKI--QEQNEEDYRQFLEDHRN 1018
Cdd:pfam02463 401 SEEEKEAQLLLELARQLedllKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLkdELELKKSEDLLKETQLV 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1019 KINEVLAAAKEDFVKQKAELLLQKETEFQACLDQSRKEWTLQEAQQTQVEIRQYEEdtlTVLAYLLKDTQLEYGGDSQDK 1098
Cdd:pfam02463 481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV---AVENYKVAISTAVIVEVSATA 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1099 QLLEAMSAC-SSKWISVQYFEKVKACIQKALHDMLSLLTDSVASEQEKRKVVKSSADTVSWTSSEGdsaVPVPLPDSTSV 1177
Cdd:pfam02463 558 DEVEERQKLvRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAK---VVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1178 RCAQSSAWLKAEAETDKKICEIKGLRCGHCFQELEKEKQECQDLRRKLEKcrRHLQHLERTHRAAVEKLGEENSRVVEEL 1257
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEK--AESELAKEEILRRQLEIKKKEQREKEEL 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1258 IEENHDMKNKL-----EALRALCRTPPRSLSAGAAESAGPSCSRQALEELRGQYIKAVRKIKRDMLRYIQESKERAAEMV 1332
Cdd:pfam02463 713 KKLKLEAEELLadrvqEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124487356 1333 KaEVLRERQETARKMRNYYLSCLQQILQDNGKEEGAEKKIMSAASKLATMAELLGTIAESD 1393
Cdd:pfam02463 793 E-EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLA 852
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
237-430 |
3.04e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.69 E-value: 3.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 237 AKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKLT 316
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 317 KKLRTTEitlESLKQQLVELH------------HSESLQRArEHHESIVASLTQKHEEQVSSLQKN---LDATITALQEQ 381
Cdd:COG4942 97 AELEAQK---EELAELLRALYrlgrqpplalllSPEDFLDA-VRRLQYLKYLAPARREQAEELRADlaeLAALRAELEAE 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 124487356 382 ESICTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQS 430
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
323-1100 |
3.94e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 52.04 E-value: 3.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 323 EITLESLKQQLVELHhsESLQRAREHHESIVASLTQK---HEEQVSSLQKNLDATITALQEQESICTRLKDHVQQLERNQ 399
Cdd:pfam15921 77 ERVLEEYSHQVKDLQ--RRLNESNELHEKQKFYLRQSvidLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 400 EAVRLEKTELINRLTRSLEDSQKqcAHLLQSGSVQEVAQLQLQLQQAQKAHVLSE---------SMNKALQEELTELKDE 470
Cdd:pfam15921 155 EAAKCLKEDMLEDSNTQIEQLRK--MMLSHEGVLQEIRSILVDFEEASGKKIYEHdsmstmhfrSLGSAISKILRELDTE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 471 IS-----LYESAAELGVLPGDSEGDLSIEL-----------TESCVDLG--IKKVNWKQSKANRVTQQESPDEDPSKDEL 532
Cdd:pfam15921 233 ISylkgrIFPVEDQLEALKSESQNKIELLLqqhqdrieqliSEHEVEITglTEKASSARSQANSIQSQLEIIQEQARNQN 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 533 ILKLKtQVQRLLTSnsvkrhlVSQLQSDLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWleSSEAINREDilQLK 612
Cdd:pfam15921 313 SMYMR-QLSDLEST-------VSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF--SQESGNLDD--QLQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 613 NEVQVLQKQNQELK-EAEEKLRSTNQDLCNQMR--QMVQEFDhDKQEAVARCERTYQQHHEAMKAQIRESLLAKHAveKQ 689
Cdd:pfam15921 381 KLLADLHKREKELSlEKEQNKRLWDRDTGNSITidHLRRELD-DRNMEVQRLEALLKAMKSECQGQMERQMAAIQG--KN 457
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 690 HLLEVYEGTQSQLRSdldkmNKEMaaVQECYLEVCREKDGLESTLRKT--MEKAQEQKRQLLEAREEYVRKLKLELEEKY 767
Cdd:pfam15921 458 ESLEKVSSLTAQLES-----TKEM--LRKVVEELTAKKMTLESSERTVsdLTASLQEKERAIEATNAEITKLRSRVDLKL 530
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 768 QET--LKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLddSLAAWRKTTSDrgsqteqvacpaavskaeaaav 845
Cdd:pfam15921 531 QELqhLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMT--QLVGQHGRTAG---------------------- 586
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 846 laEEQARQVQQEKELATKealrkpevELELKYCEIIAQKVETAVQNARSR----WIQELPMLAEYKALLRA----QQQEW 917
Cdd:pfam15921 587 --AMQVEKAQLEKEINDR--------RLELQEFKILKDKKDAKIRELEARvsdlELEKVKLVNAGSERLRAvkdiKQERD 656
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 918 AKQQELAVAHRLSLALSEAKEKWKSELENMKPNV-MSVKELEEKVHSLQKELE-----LKDEEVPVIVRAEVAKARTEWN 991
Cdd:pfam15921 657 QLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMeTTTNKLKMQLKSAQSELEqtrntLKSMEGSDGHAMKVAMGMQKQI 736
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 992 KEKQEEIHKIQEQ---------NEEDYRQFLEDHRNKINEVLAAAKEDFVKQKAEL---------LLQKETEFQACLDQS 1053
Cdd:pfam15921 737 TAKRGQIDALQSKiqfleeamtNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELevlrsqerrLKEKVANMEVALDKA 816
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 124487356 1054 rkewTLQEAQQTQVEIRQYEEDTLTVLAYLLKDTQLEYGGDSQDKQL 1100
Cdd:pfam15921 817 ----SLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSM 859
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
230-805 |
4.25e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.86 E-value: 4.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 230 QLQVLNKAKER---QLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVE 306
Cdd:COG1196 261 ELAELEAELEElrlELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 307 AFRVSEEKLTKKLRTTEITLESLKQQLVELHHS-ESLQRAREHHESIVASLTQKHEEQVSSLQKNLDATITALQEQESIC 385
Cdd:COG1196 341 ELEEELEEAEEELEEAEAELAEAEEALLEAEAElAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 386 TRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQsgsVQEVAQLQLQLQQAQKAHVLSESMNKALQEELT 465
Cdd:COG1196 421 EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL---LAELLEEAALLEAALAELLEELAEAAARLLLLL 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 466 ELKDEISLYESAA--------------ELGVLPGDS---EGDLSIELTESCVDLGIKKVN--------WKQSKANRVTQQ 520
Cdd:COG1196 498 EAEADYEGFLEGVkaalllaglrglagAVAVLIGVEaayEAALEAALAAALQNIVVEDDEvaaaaieyLKAAKAGRATFL 577
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 521 ESPDEDPSKDELILKLKTQVQRlltsnsvkrhLVSQLQSDLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWLESS 600
Cdd:COG1196 578 PLDKIRARAALAAALARGAIGA----------AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLR 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 601 EAINREDILQLKNEVQVLQKQNQELKEAEEKLRstnqdlcnqMRQMVQEFDHDKQEAVARCERTYQQHHEAMKAQIRESL 680
Cdd:COG1196 648 EVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE---------LEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 681 LAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQEcylevcrEKDGLESTLRKTMEKAQEQKRQL----LEAREEYV 756
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL-------PEPPDLEELERELERLEREIEALgpvnLLAIEEYE 791
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 124487356 757 rklklELEEKYQEtLKTERQSwLQEqaagatqqaEKESRQKLIQQLEKE 805
Cdd:COG1196 792 -----ELEERYDF-LSEQRED-LEE---------ARETLEEAIEEIDRE 824
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
239-423 |
1.57e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.07 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 239 ERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAalEAQVEAFRVSEEKLTKK 318
Cdd:TIGR02169 729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLS--HSRIPEIQAELSKLEEE 806
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 319 LRTTEITLESLKQQLVELH-HSESLQRAREHHESIVASLtqkhEEQVSSLQKNLDATITALQEQESICTRLKDHVQQLER 397
Cdd:TIGR02169 807 VSRIEARLREIEQKLNRLTlEKEYLEKEIQELQEQRIDL----KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882
|
170 180
....*....|....*....|....*.
gi 124487356 398 NQEAVRLEKTELINRLtRSLEDSQKQ 423
Cdd:TIGR02169 883 RLGDLKKERDELEAQL-RELERKIEE 907
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
589-1391 |
3.37e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 3.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 589 EKTTKQLwLESSEAINR-EDIL-QLKNEVQVLQKQnqelKEAEEKLRstnqdlcnqmRQMVQEFDHDKQEAVARCERtYQ 666
Cdd:TIGR02168 175 KETERKL-ERTRENLDRlEDILnELERQLKSLERQ----AEKAERYK----------ELKAELRELELALLVLRLEE-LR 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 667 QHHEAMKAQIRESLLAKHAVEKQhlLEVYEGTQSQLRSDLDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKR 746
Cdd:TIGR02168 239 EELEELQEELKEAEEELEELTAE--LQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 747 QLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGatQQAEKESRQKLIQQLEKewqsklddslaawrkttsdrgs 826
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELES--LEAELEELEAELEELES---------------------- 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 827 qteqvacpaavskaeaaavlaeeqaRQVQQEKELatkEALRKPEVELELKyceiiaqkvETAVQNARSRWIQELPMLAEY 906
Cdd:TIGR02168 373 -------------------------RLEELEEQL---ETLRSKVAQLELQ---------IASLNNEIERLEARLERLEDR 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 907 KALLRAQQQEWAKQQELAVAHRLSLALSEAKEkwksELEnmkpnvmsvkELEEKVHSLQKELELKDEEVPVIVRAEVAKA 986
Cdd:TIGR02168 416 RERLQQEIEELLKKLEEAELKELQAELEELEE----ELE----------ELQEELERLEEALEELREELEEAEQALDAAE 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 987 RTEWNKEKQEEIHKIQEQNEEDYRQ---FLEDHRNKINEVLAAAKeDFVKQKAELLLQKETEFQACLDQSRKEwTLQEAQ 1063
Cdd:TIGR02168 482 RELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGILGVLS-ELISVDEGYEAAIEAALGGRLQAVVVE-NLNAAK 559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1064 QTQVEIRQYEEDTLTVLAY-LLKDTQLEYGGDSQDKQLLEAMSACSSkwisvqyFEKVKACIQKALHDMLS--LLTDSVA 1140
Cdd:TIGR02168 560 KAIAFLKQNELGRVTFLPLdSIKGTEIQGNDREILKNIEGFLGVAKD-------LVKFDPKLRKALSYLLGgvLVVDDLD 632
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1141 SEQEKRKVVKSSAdtvSWTSSEGDSAVP----VPLPDST-SVRCAQSSAWLKAEAETDKKICEIKGLRcghcfQELEKEK 1215
Cdd:TIGR02168 633 NALELAKKLRPGY---RIVTLDGDLVRPggviTGGSAKTnSSILERRREIEELEEKIEELEEKIAELE-----KALAELR 704
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1216 QECQDLRRKLEKCRRHLQHLERTHRAAVEKLG--EENSRVVEELIEENHDMKNKLEALRALCRTPPRSLSAGAAESAGps 1293
Cdd:TIGR02168 705 KELEELEEELEQLRKELEELSRQISALRKDLArlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA-- 782
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1294 cSRQALEELRGQYIKAVRKIKRdmlryIQESKERAAEMVKAEvLRERQETARKMRNYYLSCLQQILQDNGKEEGAEKKIM 1373
Cdd:TIGR02168 783 -EIEELEAQIEQLKEELKALRE-----ALDELRAELTLLNEE-AANLRERLESLERRIAATERRLEDLEEQIEELSEDIE 855
|
810
....*....|....*...
gi 124487356 1374 SAASKLATMAELLGTIAE 1391
Cdd:TIGR02168 856 SLAAEIEELEELIEELES 873
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
605-816 |
1.29e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 605 REDILQLKNEVQVLQKQ----NQELKEAEEKLRSTNQDLcNQMRQMVQEFDHDKQEAVARcERTYQQHHEAMKAQIRESL 680
Cdd:COG4942 33 QQEIAELEKELAALKKEekalLKQLAALERRIAALARRI-RALEQELAALEAELAELEKE-IAELRAELEAQKEELAELL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 681 LAKHAVEKQHLLEVYEGTQS--QLRSDLDKMNKEMAAVQECYLEVCREKDGLEsTLRKTMEKAQEQKRQLLEAREEYVRK 758
Cdd:COG4942 111 RALYRLGRQPPLALLLSPEDflDAVRRLQYLKYLAPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAA 189
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 124487356 759 LKLELEEKyQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQLEKEWQSKLDDSLAA 816
Cdd:COG4942 190 LEALKAER-QKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
603-1077 |
1.88e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.30 E-value: 1.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 603 INREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLcNQMRQMVQEFDHDKQeavarcertyqqhheamkaqireslLA 682
Cdd:COG4717 68 LNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL-EELEAELEELREELE-------------------------KL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 683 KHAVEKQHLLEVYEGTQSQLRSDLDKMNKEMAAVQEcYLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVRKLKLE 762
Cdd:COG4717 122 EKLLQLLPLYQELEALEAELAELPERLEELEERLEE-LRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 763 LEE--KYQETLKTERQSWlQEQAAGATQQAEKESRQKLIQQLEKEWQSKLD-----DSLAAWRKTTSDRGSQTEQVACPA 835
Cdd:COG4717 201 LEElqQRLAELEEELEEA-QEELEELEEELEQLENELEAAALEERLKEARLllliaAALLALLGLGGSLLSLILTIAGVL 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 836 AVSKAEAAAVLAEEQARQVQQEKELATKEALRKPEVELELKYCEIIAqKVETAVQNARSRWIQELPMLAEYKALLRAQQQ 915
Cdd:COG4717 280 FLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLA-ALGLPPDLSPEELLELLDRIEELQELLREAEE 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 916 EWAKQQELAVAHRLSLALSEAKEKWKSELENMKPNVMSVKELEEKVHSLQKELELKDEEVPVIVRAEVakaRTEWNKEKQ 995
Cdd:COG4717 359 LEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALD---EEELEEELE 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 996 EEIHKIQEQNEEdyRQFLEDHRNKINEVLAAAKEDfvkQKAELLLQKETEFQACLDQSRKEWTLQEAQQTQVE--IRQYE 1073
Cdd:COG4717 436 ELEEELEELEEE--LEELREELAELEAELEQLEED---GELAELLQELEELKAELRELAEEWAALKLALELLEeaREEYR 510
|
....
gi 124487356 1074 EDTL 1077
Cdd:COG4717 511 EERL 514
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
734-978 |
2.02e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.45 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 734 LRKTMEKAQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKL------IQQLEKEwQ 807
Cdd:COG4913 240 AHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELarleaeLERLEAR-L 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 808 SKLDDSLAAWRKTTSDRGSQTEQVAcpaavskaeaaavlaeeqARQVQQ-EKELATKEALRKpEVELELKYCEIIAQKVE 886
Cdd:COG4913 319 DALREELDELEAQIRGNGGDRLEQL------------------EREIERlERELEERERRRA-RLEALLAALGLPLPASA 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 887 TAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQElavahrlslALSEAKEKWKSELENMKPNVMSV-KELEEKVHSLQ 965
Cdd:COG4913 380 EEFAALRAEAAALLEALEEELEALEEALAEAEAALR---------DLRRELRELEAEIASLERRKSNIpARLLALRDALA 450
|
250
....*....|...
gi 124487356 966 KELELKDEEVPVI 978
Cdd:COG4913 451 EALGLDEAELPFV 463
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
366-1045 |
2.50e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 45.87 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 366 SLQKNLDATITALQEQESICTRLKDHVQQLERNQEAVRLEKTELI--NRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQL 443
Cdd:pfam05483 96 SIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIqeNKDLIKENNATRHLCNLLKETCARSAEKTKKYE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 444 QQAQKAHVLSESMNKALQEELTELkDEISLYESAAELGVLPGDSEGDLSIELTESCVDlgiKKVNWKQSKANRVTQQESP 523
Cdd:pfam05483 176 YEREETRQVYMDLNNNIEKMILAF-EELRVQAENARLEMHFKLKEDHEKIQHLEEEYK---KEINDKEKQVSLLLIQITE 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 524 DEDPSKD-------------ELILKLKTQVQRLLTSNSVKRHLVSQLQsDLRECRETMEAFQQSKDGDSGMETKTD---T 587
Cdd:pfam05483 252 KENKMKDltflleesrdkanQLEEKTKLQDENLKELIEKKDHLTKELE-DIKMSLQRSMSTQKALEEDLQIATKTIcqlT 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 588 SEKTTKQLWLESSEAINREDILQLKNEV----QVLQKQNQELKEAEEKLRSTNQDLCNQMRQMvqefdhdkqEAVARCER 663
Cdd:pfam05483 331 EEKEAQMEELNKAKAAHSFVVTEFEATTcsleELLRTEQQRLEKNEDQLKIITMELQKKSSEL---------EEMTKFKN 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 664 TYQQHHEAMKAQIRES---LLAKHAVEKqhLLEVYEGTQSQLRSDLDKMNKEmaaVQECYLEVCREKDGLESTLRKTMEK 740
Cdd:pfam05483 402 NKEVELEELKKILAEDeklLDEKKQFEK--IAEELKGKEQELIFLLQAREKE---IHDLEIQLTAIKTSEEHYLKEVEDL 476
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 741 AQEQKRQLLEAREEYVRKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQ-KLIQQLEkEWQSKLDDSLAAWRK 819
Cdd:pfam05483 477 KTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMlKQIENLE-EKEMNLRDELESVRE 555
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 820 TTSDRGsqtEQVACpaavskaeaaavlaeeqarQVQQEKELATKEALRKPEVELELKYCEIIAQKVETAVQNaRSRWIQE 899
Cdd:pfam05483 556 EFIQKG---DEVKC-------------------KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN-KNKNIEE 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 900 LPMlaEYKALLRAQQQEWAKQQELAV-AHRLSLALSEAKEKW--------------KSELENMKPNVMSVKELEEKVHSL 964
Cdd:pfam05483 613 LHQ--ENKALKKKGSAENKQLNAYEIkVNKLELELASAKQKFeeiidnyqkeiedkKISEEKLLEEVEKAKAIADEAVKL 690
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 965 QKELELKDEEVPVIVRAEVAKARTEWNKEKQEE-----IHKIQEQNEEDYRQFLEDHRNKI-NEVLAAAKEDFVKQKAEL 1038
Cdd:pfam05483 691 QKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERdselgLYKNKEQEQSSAKAALEIELSNIkAELLSLKKQLEIEKEEKE 770
|
....*..
gi 124487356 1039 LLQKETE 1045
Cdd:pfam05483 771 KLKMEAK 777
|
|
| LCD1 |
pfam09798 |
DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. ... |
230-345 |
3.97e-04 |
|
DNA damage checkpoint protein; This is a family of proteins which regulate checkpoint kinases. In Schizosaccharomyces pombe this protein is called Rad26 and in Saccharomyces cerevisiae it is called LCD1.
Pssm-ID: 462906 Cd Length: 615 Bit Score: 45.00 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 230 QLQVLNKAKERQLDSL---VEKLKDS-ERQVRYLSHQLLIVQDEKDGLalsLRESQQLFqngkeremqlEAQIAALEAQV 305
Cdd:pfam09798 5 KLELLQQEKEKELEKLknsYEELKSShEEELEKLKQEVQKLEDEKKFL---LNELRSLS----------ATSPASSQSHE 71
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 124487356 306 EAFRVSEEKLTKKLRTTEITLESLKQQLVELHHSESLQRA 345
Cdd:pfam09798 72 TDTDDSSSVSLKKRKIEESTAESLKQKYIRLQNNRIVDET 111
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
227-807 |
4.66e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.11 E-value: 4.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 227 HIIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEK------------------DGLALSLRESQQLFQNGK 288
Cdd:pfam15921 265 HQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQArnqnsmymrqlsdlestvSQLRSELREAKRMYEDKI 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 289 EremQLEAQIAALEAQVEAFRVSEEKLTKKLRTTEITLESLkqqLVELHHSESLQRAREHHESIVASLTQKHEEQVSSLQ 368
Cdd:pfam15921 345 E---ELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL---LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLR 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 369 KNLDATITALQEQESICTRLKDHVQ-QLERNQEAV--RLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQLQLQLQQ 445
Cdd:pfam15921 419 RELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIqgKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTV 498
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 446 AQKAHVLSESMN--KALQEELTELKDEISLyeSAAELGVLpgDSEGDLSIELTESCVDLGIKKVnwKQSKANRVTQQESp 523
Cdd:pfam15921 499 SDLTASLQEKERaiEATNAEITKLRSRVDL--KLQELQHL--KNEGDHLRNVQTECEALKLQMA--EKDKVIEILRQQI- 571
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 524 dedpskdELILKLKTQVQRLLTSNSVKRhlvSQLQSDLRECRETMEAFQQSKDGDsgmETKTDTSEKTTKQLWLESSEAI 603
Cdd:pfam15921 572 -------ENMTQLVGQHGRTAGAMQVEK---AQLEKEINDRRLELQEFKILKDKK---DAKIRELEARVSDLELEKVKLV 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 604 N------------REDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARCERTyqqhhea 671
Cdd:pfam15921 639 NagserlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQT------- 711
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 672 mkaqiRESLLAKHAVEKqHLLEVYEGTQSQL---RSDLDKMNKEMAAVQECYLEVCREKDGL---ESTLRKTMEKAQEQK 745
Cdd:pfam15921 712 -----RNTLKSMEGSDG-HAMKVAMGMQKQItakRGQIDALQSKIQFLEEAMTNANKEKHFLkeeKNKLSQELSTVATEK 785
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124487356 746 RQlLEAREEYVRKLKLELEEKYQETLKTERQSWLQ-EQAAGATQQAEKES-RQKLIQQLE-KEWQ 807
Cdd:pfam15921 786 NK-MAGELEVLRSQERRLKEKVANMEVALDKASLQfAECQDIIQRQEQESvRLKLQHTLDvKELQ 849
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
201-403 |
5.50e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 5.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 201 VAASDMFEGLQQQFLGANETDSAENIHIIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLAlslRES 280
Cdd:COG4942 16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE---KEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 281 QQLFQNGKEREMQLEAQIAAL---------------EAQVEAFRVSE---------EKLTKKLRTTEITLESLKQQLVEL 336
Cdd:COG4942 93 AELRAELEAQKEELAELLRALyrlgrqpplalllspEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 124487356 337 HHS-ESLQRAREHHESIVASLTQKHEEQVSSLQKNLDATITALQEQESICTRLKDHVQQLERNQEAVR 403
Cdd:COG4942 173 RAElEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
608-969 |
6.50e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 44.73 E-value: 6.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 608 ILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQM--RQMVQEFDHDKQEAVARCERTYQQHHeamkaqiresllaKHA 685
Cdd:pfam17380 277 IVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVerRRKLEEAEKARQAEMDRQAAIYAEQE-------------RMA 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 686 VEKQHLLEvyegtqsQLRSDLDKMNKEMAAVQECYLEVCREKDgLEstlRKTMEKAQ--EQKRQLLEAreeyVRKLKLel 763
Cdd:pfam17380 344 MERERELE-------RIRQEERKRELERIRQEEIAMEISRMRE-LE---RLQMERQQknERVRQELEA----ARKVKI-- 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 764 eekyqetLKTERQSWLQEQAAGATQ--QAEKESRQKLIQQLEKEWQSKLDDSlaawRKTTSDRGSQTEQVacpaavskAE 841
Cdd:pfam17380 407 -------LEEERQRKIQQQKVEMEQirAEQEEARQREVRRLEEERAREMERV----RLEEQERQQQVERL--------RQ 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 842 AAAVLAEEQARQVQQEKELATKEALRKPEVELELKyceiiaQKVETAVQNARSRWIQELPMLAEYKALLRAQQ-----QE 916
Cdd:pfam17380 468 QEEERKRKKLELEKEKRDRKRAEEQRRKILEKELE------ERKQAMIEEERKRKLLEKEMEERQKAIYEEERrreaeEE 541
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 124487356 917 WAKQQELAVAHRLSLALSEAKEKwKSELENMKPNVMSVKELEEKvHSLQKELE 969
Cdd:pfam17380 542 RRKQQEMEERRRIQEQMRKATEE-RSRLEAMEREREMMRQIVES-EKARAEYE 592
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
259-926 |
6.57e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 44.74 E-value: 6.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 259 LSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAFRVSEEKlTKKLRTTEITLESLKQQLVELHH 338
Cdd:pfam07111 61 LSQQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAE-AEGLRAALAGAEMVRKNLEEGSQ 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 339 SEsLQRAREHHESIVASLTQKHEEQVSSLQKNLDATITALQEQEsicTRLKDHVQQLERNQEAVRLekteLINRLTRSLE 418
Cdd:pfam07111 140 RE-LEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLE---TKRAGEAKQLAEAQKEAEL----LRKQLSKTQE 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 419 DSQKQCAHL--LQSGSVQEVAQLQLQLQQAQKAHVLSESMN-------------KALQEELTELKDEISLYESAAELGVL 483
Cdd:pfam07111 212 ELEAQVTLVesLRKYVGEQVPPEVHSQTWELERQELLDTMQhlqedradlqatvELLQVRVQSLTHMLALQEEELTRKIQ 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 484 PGDSegdLSIELTESCVDLgikKVNWKQSKANRVTQQESpdEDPSKDELILKLKTQVQRLLTSNSVKRHLVSQLQSDLRE 563
Cdd:pfam07111 292 PSDS---LEPEFPKKCRSL---LNRWREKVFALMVQLKA--QDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQD 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 564 CRETMEAFQQSKDGDSgMETKTDTSEKTTKQLWLESSEAINREDILQLKNEVQVLQKQNQELKEAEEKLRSTNQDLCNQM 643
Cdd:pfam07111 364 KAAEVEVERMSAKGLQ-MELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAV 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 644 RQMvqefdHDKQEAVARCERTYQQHHEAMK-AQIRESLLAKHAVEKQHLLEVYEGTQSQLRSDLDKMNKemaavqecylE 722
Cdd:pfam07111 443 RKV-----HTIKGLMARKVALAQLRQESCPpPPPAPPVDADLSLELEQLREERNRLDAELQLSAHLIQQ----------E 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 723 VCREKDGLESTLRKTMEKAQEQKRQLLEAREEYVrKLKLELEEKYQETLKTERQSWLQEQAAGATQQAEKESRQKLIQQL 802
Cdd:pfam07111 508 VGRAREQGEAERQQLSEVAQQLEQELQRAQESLA-SVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEV 586
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 803 EKEWQSKLDDSLaawRKTTSDRGSQTEQVACPAAVSKAEAAAVLAEEQARQVQQE--KELATKEALRKPEVELELKYCEI 880
Cdd:pfam07111 587 ETRLREQLSDTK---RRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEarKEEGQRLARRVQELERDKNLMLA 663
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 124487356 881 IAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQELAVA 926
Cdd:pfam07111 664 TLQQEGLLSRYKQQRLLAVLPSGLDKKSVVSSPRPECSASAPIPAA 709
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
280-1065 |
1.25e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.88 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 280 SQQLFQNGKEREMQLEAQIAALEAQVEAFRvseekltKKLRTTEITLESLKQQLVELHHSES------------------ 341
Cdd:TIGR00606 208 ELKYLKQYKEKACEIRDQITSKEAQLESSR-------EIVKSYENELDPLKNRLKEIEHNLSkimkldneikalksrkkq 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 342 LQRAREHHESIVASLTQKHEEQVSSLQKNLDATITALQEQESICTRlkdHVQQLERNQEAVRLEKTELINRLTR-SLEDS 420
Cdd:TIGR00606 281 MEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQR---ELEKLNKERRLLNQEKTELLVEQGRlQLQAD 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 421 QKQCAHLLQSGSVQEVAQLQL---------------------QLQQAQKAHVLSESMN------KALQEELTELKDEISL 473
Cdd:TIGR00606 358 RHQEHIRARDSLIQSLATRLEldgfergpfserqiknfhtlvIERQEDEAKTAAQLCAdlqskeRLKQEQADEIRDEKKG 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 474 YESAAELGvlpgdsegdlSIELTESCVDLGIKKVNWKQSKA--NRVTQQESPDEDPSKDELILKLKTQVQRLLTSNSVKR 551
Cdd:TIGR00606 438 LGRTIELK----------KEILEKKQEELKFVIKELQQLEGssDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQ 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 552 HLVSQLQSDLRECRETMEAFQQSKDGDSGMET----KTDTSEKTTKQLWLESSEAINREDILQLKNEVQ-VLQKQNQELK 626
Cdd:TIGR00606 508 NEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMltkdKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEdWLHSKSKEIN 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 627 EAEEKLRSTNQDLCN--QMRQMVQEFDHDKQEAVARCE---------RTYQQHHEAMKAQIRES------LLAKHAVEKQ 689
Cdd:TIGR00606 588 QTRDRLAKLNKELASleQNKNHINNELESKEEQLSSYEdklfdvcgsQDEESDLERLKEEIEKSskqramLAGATAVYSQ 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 690 HLLEVYEGTQS---------QLRSDLDKMNKEMaavQECYLEVCREKDGLESTLRKtMEKAQEQKRQLLEAREEYVRKLK 760
Cdd:TIGR00606 668 FITQLTDENQSccpvcqrvfQTEAELQEFISDL---QSKLRLAPDKLKSTESELKK-KEKRRDEMLGLAPGRQSIIDLKE 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 761 LELEE------KYQETLKTERQSWLQEQAAGATQQAEKESRQKLiqQLEKEWQSKLDDSLAAWRKTTSDRGSQTEQVACP 834
Cdd:TIGR00606 744 KEIPElrnklqKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVC--LTDVTIMERFQMELKDVERKIAQQAAKLQGSDLD 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 835 AAVSKAEAAAVLAEEQARQVQQEKELATK--EALRKPEVELELKYCEIIAQKVE--TAVQNARSRWIQELPMLAEYKALL 910
Cdd:TIGR00606 822 RTVQQVNQEKQEKQHELDTVVSKIELNRKliQDQQEQIQHLKSKTNELKSEKLQigTNLQRRQQFEEQLVELSTEVQSLI 901
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 911 RAQQQewAKQQELAVAHRLSLALSEAKEKWKSELENMKPNVMSVKELEEKVHslQKELELKDEEvpvivrAEVAKARTEW 990
Cdd:TIGR00606 902 REIKD--AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK--NIHGYMKDIE------NKIQDGKDDY 971
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124487356 991 NKEKQEEIHKIQEQNEEDyrqflEDHRNKINEVLAAAKEDFVKQKaelllQKETEFQACLDQSRKEWTLQEAQQT 1065
Cdd:TIGR00606 972 LKQKETELNTVNAQLEEC-----EKHQEKINEDMRLMRQDIDTQK-----IQERWLQDNLTLRKRENELKEVEEE 1036
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
208-418 |
1.39e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 208 EGLQQQFLGANETDSAENIHIIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNG 287
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 288 KEREMQLEAQIAALEAQVEAFRVSEEKLTKKLRTTEITLESLKQQLVEL-HHSESLQRAREHHESIVASLTQKHEE---- 362
Cdd:TIGR02168 844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrSELEELSEELRELESKRSELRRELEElrek 923
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124487356 363 ------QVSSLQKNLDATITALQEQESIctrLKDHVQQLERNQEAVRLEKTELINRLTRSLE 418
Cdd:TIGR02168 924 laqlelRLEGLEVRIDNLQERLSEEYSL---TLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| GBP_C |
cd16269 |
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
610-803 |
1.68e-03 |
|
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.
Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 42.56 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 610 QLKNEVQVLQKQNQElkEAEEKLRSTNQDLCNQMRQMVQEFDHDKQEAVARcertYQQHHEAMKAQIRES----LLAKHA 685
Cdd:cd16269 98 QLEEKKEEFCKQNEE--ASSKRCQALLQELSAPLEEKISQGSYSVPGGYQL----YLEDREKLVEKYRQVprkgVKAEEV 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 686 VekQHLLEVYEGT-QSQLRSD--LDKMNKEMAAVQECYLEVCREKDGLESTLRKTMEKAQEQKRQLlearEEYVRKLKLE 762
Cdd:cd16269 172 L--QEFLQSKEAEaEAILQADqaLTEKEKEIEAERAKAEAAEQERKLLEEQQRELEQKLEDQERSY----EEHLRQLKEK 245
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 124487356 763 LEEKYQETLKTERQ---SWLQEQAAGATQQAEKESR--QKLIQQLE 803
Cdd:cd16269 246 MEEERENLLKEQERaleSKLKEQEALLEEGFKEQAEllQEEIRSLK 291
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
853-1075 |
3.02e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.42 E-value: 3.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 853 QVQQEKELATKEALRKPEVELEL-KYCEIIAQKVETAVQNARSRwiQELPMLAEYKALLRAQQQEWakQQELAVAHRLSL 931
Cdd:pfam17380 352 RIRQEERKRELERIRQEEIAMEIsRMRELERLQMERQQKNERVR--QELEAARKVKILEEERQRKI--QQQKVEMEQIRA 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 932 ALSEAKEKWKSELENMKPNVMSVKELEEKVHSLQKELELKDEEVPVIVRAEVAKARTEwNKEKQEEIHKIQEQN-EEDYR 1010
Cdd:pfam17380 428 EQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRD-RKRAEEQRRKILEKElEERKQ 506
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124487356 1011 QFLEDHRNKinEVLAAAKEDfvKQKAellLQKETEFQACLDQSRKEWTLQEAQQTQVEIRQYEED 1075
Cdd:pfam17380 507 AMIEEERKR--KLLEKEMEE--RQKA---IYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
186-417 |
4.04e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.97 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 186 YRNSSVQKNSSPAQEVAASDMFEGLQQQFLGANETDSAENIHIIQLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLI 265
Cdd:TIGR02168 819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 266 VQDEkdglalslresqqlfQNGKEREMQ-LEAQIAALEAQVEAFRVSEEKLtkklrttEITLESLKQQLVElHHSESLQR 344
Cdd:TIGR02168 899 LSEE---------------LRELESKRSeLRRELEELREKLAQLELRLEGL-------EVRIDNLQERLSE-EYSLTLEE 955
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124487356 345 AREHHESIVASLtQKHEEQVSSLQKNLDA----TITALQEQESICTRLKDHVQQLERNQEAVR-LEKT-ELINRLTRSL 417
Cdd:TIGR02168 956 AEALENKIEDDE-EEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKEtLEEAiEEIDREARER 1033
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
856-1074 |
5.65e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.59 E-value: 5.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 856 QEKELATKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQQEWAKQQELAVAHRLSL-ALS 934
Cdd:TIGR02169 671 SEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLsSLE 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 935 EAKEKWKSElenMKPNVMSVKELEEKVHSLQKELE-LKDEEVPVIVRAEVAKARtewnkeKQEEIHKIQEQNEEDYRQFL 1013
Cdd:TIGR02169 751 QEIENVKSE---LKELEARIEELEEDLHKLEEALNdLEARLSHSRIPEIQAELS------KLEEEVSRIEARLREIEQKL 821
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124487356 1014 EDhRNKINEVLAAAKEDFVKQKAELLLQKETEFQAC-LDQSRKEWTLQEAQQTQVEIRQYEE 1074
Cdd:TIGR02169 822 NR-LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIeNLNGKKEELEEELEELEAALRDLES 882
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
211-638 |
5.80e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 5.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 211 QQQFLGANEtdsaENIHIIQLQVLNKAKERQLDSLVEKLKDSERQvrylshQLLIVQDEKDGLALSLRESQQLFQNGKER 290
Cdd:pfam05483 368 EQQRLEKNE----DQLKIITMELQKKSSELEEMTKFKNNKEVELE------ELKKILAEDEKLLDEKKQFEKIAEELKGK 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 291 EMQL-------EAQIAALEAQVEAFRVSEEKLTKKLRTTEITLESLKQQLVEL-HHSESLQRAREHHESIVASLT---QK 359
Cdd:pfam05483 438 EQELifllqarEKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELtAHCDKLLLENKELTQEASDMTlelKK 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 360 HEEQVSSLQKNLDATITALQEQESICTRLKDhvqQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQEVAQL 439
Cdd:pfam05483 518 HQEDIINCKKQEERMLKQIENLEEKEMNLRD---ELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILEN 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 440 Q---LQLQQAQKAHVLSE--SMNKALQEELTELKDEISLYESAAElgvlpgdsegDLSIELTESCVDLGIKKVNWKQSKA 514
Cdd:pfam05483 595 KcnnLKKQIENKNKNIEElhQENKALKKKGSAENKQLNAYEIKVN----------KLELELASAKQKFEEIIDNYQKEIE 664
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 515 NRVTQQESPDEDPSKDELILKLKTQVQRLLTSNSvkRHLVSQLQSDLRECRETMEAFQQSKDGDSGMeTKTDTSEKTTKQ 594
Cdd:pfam05483 665 DKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRC--QHKIAEMVALMEKHKHQYDKIIEERDSELGL-YKNKEQEQSSAK 741
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 124487356 595 LWLESseainreDILQLKNEVQVLQKQNQELKEAEEKLRSTNQD 638
Cdd:pfam05483 742 AALEI-------ELSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
739-808 |
5.82e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.35 E-value: 5.82e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 124487356 739 EKAQEQKRQLLEAREEYVRKLKLELE---EKYQETLKTERQSwLQEQAAGATQQAEKESRQ--KLIQQLEKEWQS 808
Cdd:PRK00409 529 ERELEQKAEEAEALLKEAEKLKEELEekkEKLQEEEDKLLEE-AEKEAQQAIKEAKKEADEiiKELRQLQKGGYA 602
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
232-426 |
6.57e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 41.31 E-value: 6.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 232 QVLNKAK---ERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKEREMQLEAQIAALEAQVEAF 308
Cdd:pfam01576 204 QELEKAKrklEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESE 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 309 RVSEEKLTKKLRTTEITLESLKQQLVE-LHHSESLQRAREHHESIVASL-------TQKHEEQVSSLQKNLDATITALQE 380
Cdd:pfam01576 284 RAARNKAEKQRRDLGEELEALKTELEDtLDTTAAQQELRSKREQEVTELkkaleeeTRSHEAQLQEMRQKHTQALEELTE 363
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 124487356 381 QESICTRLKdhvQQLERNQEAVRLEKTELINRLtRSLEDSQKQCAH 426
Cdd:pfam01576 364 QLEQAKRNK---ANLEKAKQALESENAELQAEL-RTLQQAKQDSEH 405
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
857-1095 |
6.95e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.43 E-value: 6.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 857 EKELATKEALRKPEVELELKYCEIIAQKVETAVQNARSRWIQELPMLAEYKALLRAQQqewakqqELAVAHRLSLALSEA 936
Cdd:PLN02939 159 EKILTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGAT-------EGLCVHSLSKELDVL 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 937 KEK---WKSELENMKPNVMSVKELEEKVHSLQKE---LE--LKDEEVPVIV-RAEVAKARTE-----WNKEK--QEEIHK 1000
Cdd:PLN02939 232 KEEnmlLKDDIQFLKAELIEVAETEERVFKLEKErslLDasLRELESKFIVaQEDVSKLSPLqydcwWEKVEnlQDLLDR 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 1001 IQEQNEE-----DYRQFLEDHRNKINEVLAAAK-EDFVKQKAELLLQKETEFQACLDQSRKEwTLQEAQQTQVEIRQYeE 1074
Cdd:PLN02939 312 ATNQVEKaalvlDQNQDLRDKVDKLEASLKEANvSKFSSYKVELLQQKLKLLEERLQASDHE-IHSYIQLYQESIKEF-Q 389
|
250 260
....*....|....*....|.
gi 124487356 1075 DTLTVLAYLLKDTQLEYGGDS 1095
Cdd:PLN02939 390 DTLSKLKEESKKRSLEHPADD 410
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
230-801 |
7.26e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.36 E-value: 7.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 230 QLQVLNKAKERQLDSLVEKLKDSERQVRYLSHQLLIVQDEKDGLALSLRESQQLFQNGKE-REMQLEAQIAALEAQVEAF 308
Cdd:pfam12128 323 ELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSkIKEQNNRDIAGIKDKLAKI 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 309 RvseEKLTKKLRTTEITLESLKQQLVElHHSESLQRAREHHESIVASLTQ--------KHEEQVSSLQKNLDATITALQE 380
Cdd:pfam12128 403 R---EARDRQLAVAEDDLQALESELRE-QLEAGKLEFNEEEYRLKSRLGElklrlnqaTATPELLLQLENFDERIERARE 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 381 QESICTRLKDHVQQLERNQEAVRLEKTELINRLTRSLEDSQKQCAHLLQSGSVQevaqlqlqlqqaqkAHVLSESMNKal 460
Cdd:pfam12128 479 EQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQ--------------AGTLLHFLRK-- 542
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 461 qeELTELKDEISLYESAAELG---VLPGDSEGDLSIELTESCVDLGIKKVnwkqskanrvtqqESPDEDPSKDELilklk 537
Cdd:pfam12128 543 --EAPDWEQSIGKVISPELLHrtdLDPEVWDGSVGGELNLYGVKLDLKRI-------------DVPEWAASEEEL----- 602
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 538 tqvqrlltsnsvkRHLVSQLQSDLRECRETMEAFQQSKDGDSGMETKTDTSEKTTKQLWLEsseaiNREDILQLKNEVQV 617
Cdd:pfam12128 603 -------------RERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN-----ARLDLRRLFDEKQS 664
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 618 LQKQ-NQELKEAEEKLRSTNQDLCNQMRQMvqefDHDKQEAVARCERTYQQHHEAMKAQIRE---SLLAKHAVEKQHLLE 693
Cdd:pfam12128 665 EKDKkNKALAERKDSANERLNSLEAQLKQL----DKKHQAWLEEQKEQKREARTEKQAYWQVvegALDAQLALLKAAIAA 740
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487356 694 VYEGTQSQLRSDLDKMNKEMAAvqecyLEVCREKDGLESTLRKTMEKAQEQKRQLLEAREEYvrklklelEEKYQETlkt 773
Cdd:pfam12128 741 RRSGAKAELKALETWYKRDLAS-----LGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRY--------FDWYQET--- 804
|
570 580
....*....|....*....|....*...
gi 124487356 774 erqsWLQEQAAGATQQAEKESRQKLIQQ 801
Cdd:pfam12128 805 ----WLQRRPRLATQLSNIERAISELQQ 828
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