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Conserved domains on  [gi|124487293|ref|NP_001074548|]
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opioid growth factor receptor-like protein 1 isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 114-319 3.43e-139

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


:

Pssm-ID: 461383  Cd Length: 208  Bit Score: 397.85  E-value: 3.43e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487293  114 RYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIR 193
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487293  194 RFLLAYKMMLEFFGIKLID-KTGNVARAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENT 272
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDeKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 124487293  273 IPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKE 319
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKL 207
Trypan_PARP super family cl42451
Procyclic acidic repetitive protein (PARP); This family consists of several Trypanosoma brucei ...
 6-84 4.61e-03

Procyclic acidic repetitive protein (PARP); This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.


The actual alignment was detected with superfamily member pfam05887:

Pssm-ID: 368653  Cd Length: 134  Bit Score: 37.46  E-value: 4.61e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124487293    6 GGVSFREPTTVEDcDSTWQTDSEPEPEqPGPAGGGEGQQHDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGEST 84
Cdd:pfam05887  39 GGKGKGKGTKVSD-DDTNGTDPEPEPE-PEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPGAAT 115
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 114-319 3.43e-139

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 397.85  E-value: 3.43e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487293  114 RYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIR 193
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487293  194 RFLLAYKMMLEFFGIKLID-KTGNVARAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENT 272
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDeKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 124487293  273 IPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKE 319
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKL 207
Trypan_PARP pfam05887
Procyclic acidic repetitive protein (PARP); This family consists of several Trypanosoma brucei ...
 6-84 4.61e-03

Procyclic acidic repetitive protein (PARP); This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.


Pssm-ID: 368653  Cd Length: 134  Bit Score: 37.46  E-value: 4.61e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124487293    6 GGVSFREPTTVEDcDSTWQTDSEPEPEqPGPAGGGEGQQHDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGEST 84
Cdd:pfam05887  39 GGKGKGKGTKVSD-DDTNGTDPEPEPE-PEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPGAAT 115
 
Name Accession Description Interval E-value
OGFr_N pfam04664
Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors ...
 114-319 3.43e-139

Opioid growth factor receptor (OGFr) conserved region; Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid growth factor receptor is an integral membrane protein associated with the nucleus. The conserved region is situated at the N-terminus of the member proteins with a series of imperfect repeats lying immediately to its C-terminus.


Pssm-ID: 461383  Cd Length: 208  Bit Score: 397.85  E-value: 3.43e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487293  114 RYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIR 193
Cdd:pfam04664   1 DQPNDMANLKFYKNEIPFQPDGIYIEEFLQKWKGDYDKLEHNHSYIQWLFPLREPGVNWRAKPLTPKEIEAFKKSEEAKR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487293  194 RFLLAYKMMLEFFGIKLID-KTGNVARAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENT 272
Cdd:pfam04664  81 RLLKSYKLMLGFYGIELLDeKTGEVKRASNWQERFQNLNRNSHNNLRITRILKSLGELGYEHYQAPLVRFFLEETLVHFT 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 124487293  273 IPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKE 319
Cdd:pfam04664 161 LPNVKQSALDYFVFTVRDKRERRELVRFAWQHYKPRGKFVWGPWDKL 207
Trypan_PARP pfam05887
Procyclic acidic repetitive protein (PARP); This family consists of several Trypanosoma brucei ...
 6-84 4.61e-03

Procyclic acidic repetitive protein (PARP); This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei encode a small family of abundant surface proteins whose expression is restricted to the procyclic form of the parasite. They are found at two unlinked loci, parpA and parpB; transcription of both loci is developmentally regulated.


Pssm-ID: 368653  Cd Length: 134  Bit Score: 37.46  E-value: 4.61e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124487293    6 GGVSFREPTTVEDcDSTWQTDSEPEPEqPGPAGGGEGQQHDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGEST 84
Cdd:pfam05887  39 GGKGKGKGTKVSD-DDTNGTDPEPEPE-PEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPGAAT 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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