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Conserved domains on  [gi|122937279|ref|NP_001073910|]
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tetratricopeptide repeat protein 36 isoform a [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11469168)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
45-163 1.55e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.70  E-value: 1.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  45 QAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarq 124
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA--- 143

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 122937279 125 sFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVL 163
Cdd:COG4785  144 -YLNRGIALYYLGRYELAIADLEKALELDPNDPERALWL 181
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
45-163 1.55e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.70  E-value: 1.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  45 QAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarq 124
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA--- 143

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 122937279 125 sFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVL 163
Cdd:COG4785  144 -YLNRGIALYYLGRYELAIADLEKALELDPNDPERALWL 181
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 80-154 2.39e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.82  E-value: 2.39e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 122937279   80 LLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGrgraARQSFVQRGLLARLQGRDDDARRDFERAARLGS 154
Cdd:TIGR00990 326 LGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPR----VTQSYIKRASMNLELGDPDKAEEDFDKALKLNS 396
TPR_12 pfam13424
Tetratricopeptide repeat;
83-152 1.26e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 1.26e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 122937279   83 ERASAYNNRAQARRLQGDVAGALEDLERAVELS----GGRGRAARQSFVQRGLLARLQGRDDDARRDFERAARL 152
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIArrllGPDHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 64-151 3.85e-04

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 40.28  E-value: 3.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  64 AGDLSTALERFGQAICLLPeRASAYNNRAQARRLQGDVAGALEDLERAVELsggrgrAARQSFVQRGLLARLQGRDDDA- 142
Cdd:PRK09782 589 PGQPELALNDLTRSLNIAP-SANAYVARATIYRQRHNVPAAVSDLRAALEL------EPNNSNYQAALGYALWDSGDIAq 661

                         90
                 ....*....|
gi 122937279 143 -RRDFERAAR 151
Cdd:PRK09782 662 sREMLERAHK 671
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 85-114 6.38e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.19  E-value: 6.38e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 122937279    85 ASAYNNRAQARRLQGDVAGALEDLERAVEL 114
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
45-163 1.55e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.70  E-value: 1.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  45 QAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarq 124
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA--- 143

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 122937279 125 sFVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVL 163
Cdd:COG4785  144 -YLNRGIALYYLGRYELAIADLEKALELDPNDPERALWL 181
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 52-152 4.24e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.00  E-value: 4.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  52 KALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQRGL 131
Cdd:COG3914  113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEA----LNNLGN 188

                         90       100
                 ....*....|....*....|.
gi 122937279 132 LARLQGRDDDARRDFERAARL 152
Cdd:COG3914  189 ALQDLGRLEEAIAAYRRALEL 209
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
49-152 8.74e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.47  E-value: 8.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQ 128
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA----LNN 81

                         90       100
                 ....*....|....*....|....
gi 122937279 129 RGLLARLQGRDDDARRDFERAARL 152
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALEL 105
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 45-161 9.04e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 53.84  E-value: 9.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  45 QAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarq 124
Cdd:COG3914   72 AALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEA--- 148

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 122937279 125 sFVQRGLLARLQGRDDDARRDFERAARL--GSPFARRQL 161
Cdd:COG3914  149 -YLNLGEALRRLGRLEEAIAALRRALELdpDNAEALNNL 186
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 45-162 7.93e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 7.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  45 QAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARq 124
Cdd:COG4235   11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALY- 89

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 122937279 125 sfvQRGLLARLQGRDDDARRDFERAARLGSPFARRQLV 162
Cdd:COG4235   90 ---LLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 49-170 5.37e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.72  E-value: 5.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAArqsfVQ 128
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEAR----LN 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 122937279 129 RGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAAL 170
Cdd:COG4783   78 LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRAL 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
53-187 6.61e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.08  E-value: 6.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  53 ALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQRGLL 132
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA----LYNLGIA 153

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 122937279 133 ARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAALCNRMLADMMGQLRRPRD 187
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 49-152 7.64e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 7.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARqsfvQ 128
Cdd:COG4783   36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYL----R 111

                         90       100
                 ....*....|....*....|....
gi 122937279 129 RGLLARLQGRDDDARRDFERAARL 152
Cdd:COG4783  112 LARAYRALGRPDEAIAALEKALEL 135
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
61-152 3.03e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.01  E-value: 3.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  61 AAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEdLERAVELSGGRGRAarqsFVQRGLLARLQGRDD 140
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEA----LLNLAELLLELGDYD 76

                         90
                 ....*....|..
gi 122937279 141 DARRDFERAARL 152
Cdd:COG3063   77 EALAYLERALEL 88
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 44-152 1.00e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  44 PQAQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAAR 123
Cdd:COG5010   47 RDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYS 126

                         90       100
                 ....*....|....*....|....*....
gi 122937279 124 qsfvQRGLLARLQGRDDDARRDFERAARL 152
Cdd:COG5010  127 ----NLAALLLSLGQDDEAKAALQRALGT 151
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 80-154 2.39e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.82  E-value: 2.39e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 122937279   80 LLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGrgraARQSFVQRGLLARLQGRDDDARRDFERAARLGS 154
Cdd:TIGR00990 326 LGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPR----VTQSYIKRASMNLELGDPDKAEEDFDKALKLNS 396
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 51-121 2.99e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 2.99e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 122937279   51 SKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRA 121
Cdd:TIGR02917 363 PAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRA 433
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
82-158 3.68e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 3.68e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 122937279  82 PERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQRGLLARLQGRDDDARRDFERAARLGSPFAR 158
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA----LYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 49-170 9.69e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 9.69e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQ 128
Cdd:COG2956  108 DDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA----LLL 183

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 122937279 129 RGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAAL 170
Cdd:COG2956  184 LAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225
TPR_12 pfam13424
Tetratricopeptide repeat;
83-152 1.26e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.91  E-value: 1.26e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 122937279   83 ERASAYNNRAQARRLQGDVAGALEDLERAVELS----GGRGRAARQSFVQRGLLARLQGRDDDARRDFERAARL 152
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIArrllGPDHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 46-170 1.38e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.52  E-value: 1.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  46 AQLEQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqs 125
Cdd:COG3914   39 AALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA---- 114

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 122937279 126 FVQRGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAAL 170
Cdd:COG3914  115 LFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
49-173 1.63e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 1.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQ 128
Cdd:COG0457  108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAA 187

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 122937279 129 RGLLARLQGRDDDARRDFERAARLGSPFARRQLVLLNPYAALCNR 173
Cdd:COG0457  188 LALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 64-151 3.85e-04

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 40.28  E-value: 3.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  64 AGDLSTALERFGQAICLLPeRASAYNNRAQARRLQGDVAGALEDLERAVELsggrgrAARQSFVQRGLLARLQGRDDDA- 142
Cdd:PRK09782 589 PGQPELALNDLTRSLNIAP-SANAYVARATIYRQRHNVPAAVSDLRAALEL------EPNNSNYQAALGYALWDSGDIAq 661

                         90
                 ....*....|
gi 122937279 143 -RRDFERAAR 151
Cdd:PRK09782 662 sREMLERAHK 671
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 53-156 4.91e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 39.97  E-value: 4.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279   53 ALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQRGLL 132
Cdd:TIGR00990 333 ALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPDI----YYHRAQL 408

                          90       100
                  ....*....|....*....|....
gi 122937279  133 ARLQGRDDDARRDFERAARLGSPF 156
Cdd:TIGR00990 409 HFIKGEFAQAGKDYQKSIDLDPDF 432
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 66-158 5.31e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 39.77  E-value: 5.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  66 DLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQRGLLARLQGRDDDARRD 145
Cdd:PLN03088  17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKA----YLRKGTACMKLEEYQTAKAA 92

                         90
                 ....*....|...
gi 122937279 146 FERAARLGSPFAR 158
Cdd:PLN03088  93 LEKGASLAPGDSR 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 49-163 7.51e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 7.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAarqsFVQ 128
Cdd:COG2956   74 DRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHA----YCE 149

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 122937279 129 RGLLARLQGRDDDARRDFERAARLGSPFARRQLVL 163
Cdd:COG2956  150 LAELYLEQGDYDEAIEALEKALKLDPDCARALLLL 184
TPR_1 pfam00515
Tetratricopeptide repeat;
85-114 9.79e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 9.79e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 122937279   85 ASAYNNRAQARRLQGDVAGALEDLERAVEL 114
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALEL 30
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
49-149 1.01e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.74  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARQSFVQ 128
Cdd:COG4785  105 DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLA 184

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 122937279 129 RGLLAR----------------LQGRDDDARRDFERA 149
Cdd:COG4785  185 ERKLDPekalallledwataylLQGDTEEARELFKLA 221
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 49-152 1.14e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.56  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALERFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAARqsfvQ 128
Cdd:COG2956  142 ENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP----R 217

                         90       100
                 ....*....|....*....|....
gi 122937279 129 RGLLARLQGRDDDARRDFERAARL 152
Cdd:COG2956  218 LAELYEKLGDPEEALELLRKALEL 241
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
49-115 2.10e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 35.92  E-value: 2.10e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 122937279  49 EQSKALELQGVMAAEAGDLSTALErFGQAICLLPERASAYNNRAQARRLQGDVAGALEDLERAVELS 115
Cdd:COG3063   24 DNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 85-114 6.38e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.19  E-value: 6.38e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 122937279    85 ASAYNNRAQARRLQGDVAGALEDLERAVEL 114
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 63-165 9.01e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 34.58  E-value: 9.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122937279  63 EAGDLSTALERFGQAICLLPE---RASAYNNRAQARRLQGDVAGALEDLERAVELSGGRGRAArQSFVQRGLLARLQGRD 139
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAP-DALLKLGLSYLELGDY 83

                         90       100
                 ....*....|....*....|....*...
gi 122937279 140 DDARRDFERAARL--GSPFARRQLVLLN 165
Cdd:COG1729   84 DKARATLEELIKKypDSEAAKEARARLA 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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