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Conserved domains on  [gi|119943123|ref|NP_001073330|]
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apolipoprotein A-IV b, tandem duplicate 1 precursor [Danio rerio]

Protein Classification

apolipoprotein A1/A4/E family protein( domain architecture ID 12019813)

apolipoprotein A1/A4/E family protein associates with lipid particles and may function in lipoprotein-mediated lipid transport

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
 66-234 2.14e-42

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


:

Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 142.40  E-value: 2.14e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123   66 RLTQSADMASEYAVTLKKQVDPLTEELMNKITKETEVLRERLGQDLINVREKLEPYADNMKSQIQQRVEELRAAMAPYAD 145
Cdd:pfam01442   1 LLEDSLDELSTYAEELQEQLGPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEPYTE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  146 SL------DSETLKATLLQKSEELRGNLEQSVKELQAQLEPYTAELKEKVDQHLQEFQETVSPLAEDLQVQIRERAQIVQ 219
Cdd:pfam01442  81 ELrkrlnaDAEELQEKLAPYGEELRERLEQNVDALRARLAPYAEELRQKLAERLEELKESLAPYAEEVQAQLSQRLQELR 160

                         170
                  ....*....|....*
gi 119943123  220 QSLTPYAEDLKEKLD 234
Cdd:pfam01442 161 EKLEPQAEDLREKLD 175
 
Name Accession Description Interval E-value
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
 66-234 2.14e-42

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 142.40  E-value: 2.14e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123   66 RLTQSADMASEYAVTLKKQVDPLTEELMNKITKETEVLRERLGQDLINVREKLEPYADNMKSQIQQRVEELRAAMAPYAD 145
Cdd:pfam01442   1 LLEDSLDELSTYAEELQEQLGPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEPYTE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  146 SL------DSETLKATLLQKSEELRGNLEQSVKELQAQLEPYTAELKEKVDQHLQEFQETVSPLAEDLQVQIRERAQIVQ 219
Cdd:pfam01442  81 ELrkrlnaDAEELQEKLAPYGEELRERLEQNVDALRARLAPYAEELRQKLAERLEELKESLAPYAEEVQAQLSQRLQELR 160

                         170
                  ....*....|....*
gi 119943123  220 QSLTPYAEDLKEKLD 234
Cdd:pfam01442 161 EKLEPQAEDLREKLD 175
ASKHA_NBD_ScArp7-like cd10212
nucleotide-binding domain (NBD) of Saccharomyces cerevisiae actin-related protein7 (Arp7) and ...
 92-202 1.22e-03

nucleotide-binding domain (NBD) of Saccharomyces cerevisiae actin-related protein7 (Arp7) and similar proteins; Saccharomyces cerevisiae Arp7, also called actin-like protein 7, is a component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. It is also part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of many genes. Arp7 forms a stable heterodimer with Arp9 protein in both the RSC and SWI/SNF chromatin-remodeling complexes. It has been suggested that this dimer functions as a module with DNA bending proteins, to achieve correct architecture and facilitate complex-complex interactions. Fission yeast SWI/SNF and RSC complexes do not contain Arp7 and Arp8, but instead contain Arp9 and Arp42.


Pssm-ID: 466818 [Multi-domain]  Cd Length: 424  Bit Score: 39.70  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  92 LMNKITKETEVLRERLGQDLIN--VREKLEPYADNMKSQIQQRVEELRAAMAPYADSLDSETLKATLLQKSEELRGNLEQ 169
Cdd:cd10212  167 IIDGIVVKNAVVRSKFGGDFLDfqVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELER 246

                         90       100       110
                 ....*....|....*....|....*....|...
gi 119943123 170 SVKElQAQLEPYTAELKEKVDQHLQEFQETVSP 202
Cdd:cd10212  247 YYKE-QADIYAKQQEQLKQMDQQLQYTALTGSP 278
GvpP COG4980
Gas vesicle protein YhaH [General function prediction only];
158-244 1.58e-03

Gas vesicle protein YhaH [General function prediction only];


Pssm-ID: 444004 [Multi-domain]  Cd Length: 106  Bit Score: 37.26  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123 158 QKSEELRGNLEQSVKELQAQLEPYTAELKEKVDQHLQEFQETVSPLAEDLQVQIreraqivqqsltpyaEDLKEKLDPYA 237
Cdd:COG4980   27 KSGKETRKKLKDKADDLKDKAEDLKDELKEKASELSEEAKEKLDELIEEIKEKI---------------EELKEEVEPKI 91


                 ....*..
gi 119943123 238 QNLKDQL 244
Cdd:COG4980   92 EELKEEA 98
 
Name Accession Description Interval E-value
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
 66-234 2.14e-42

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 142.40  E-value: 2.14e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123   66 RLTQSADMASEYAVTLKKQVDPLTEELMNKITKETEVLRERLGQDLINVREKLEPYADNMKSQIQQRVEELRAAMAPYAD 145
Cdd:pfam01442   1 LLEDSLDELSTYAEELQEQLGPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEPYTE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  146 SL------DSETLKATLLQKSEELRGNLEQSVKELQAQLEPYTAELKEKVDQHLQEFQETVSPLAEDLQVQIRERAQIVQ 219
Cdd:pfam01442  81 ELrkrlnaDAEELQEKLAPYGEELRERLEQNVDALRARLAPYAEELRQKLAERLEELKESLAPYAEEVQAQLSQRLQELR 160

                         170
                  ....*....|....*
gi 119943123  220 QSLTPYAEDLKEKLD 234
Cdd:pfam01442 161 EKLEPQAEDLREKLD 175
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
 123-251 2.69e-13

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 66.13  E-value: 2.69e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  123 DNMKSqIQQRVEELRAAMAPYADsldseTLKATLLQKSEELRGNLEQSVKELQAQLEPYTAELKEKVDQHLQEFQETVSP 202
Cdd:pfam01442   4 DSLDE-LSTYAEELQEQLGPVAQ-----ELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLEP 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 119943123  203 LAEDLQVQIRERAQIVQQSLTPYAEDLKEKLDPYAQNLKDQLISLYDSF 251
Cdd:pfam01442  78 YTEELRKRLNADAEELQEKLAPYGEELRERLEQNVDALRARLAPYAEEL 126
ASKHA_NBD_ScArp7-like cd10212
nucleotide-binding domain (NBD) of Saccharomyces cerevisiae actin-related protein7 (Arp7) and ...
 92-202 1.22e-03

nucleotide-binding domain (NBD) of Saccharomyces cerevisiae actin-related protein7 (Arp7) and similar proteins; Saccharomyces cerevisiae Arp7, also called actin-like protein 7, is a component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. It is also part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of many genes. Arp7 forms a stable heterodimer with Arp9 protein in both the RSC and SWI/SNF chromatin-remodeling complexes. It has been suggested that this dimer functions as a module with DNA bending proteins, to achieve correct architecture and facilitate complex-complex interactions. Fission yeast SWI/SNF and RSC complexes do not contain Arp7 and Arp8, but instead contain Arp9 and Arp42.


Pssm-ID: 466818 [Multi-domain]  Cd Length: 424  Bit Score: 39.70  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  92 LMNKITKETEVLRERLGQDLIN--VREKLEPYADNMKSQIQQRVEELRAAMAPYADSLDSETLKATLLQKSEELRGNLEQ 169
Cdd:cd10212  167 IIDGIVVKNAVVRSKFGGDFLDfqVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELER 246

                         90       100       110
                 ....*....|....*....|....*....|...
gi 119943123 170 SVKElQAQLEPYTAELKEKVDQHLQEFQETVSP 202
Cdd:cd10212  247 YYKE-QADIYAKQQEQLKQMDQQLQYTALTGSP 278
GvpP COG4980
Gas vesicle protein YhaH [General function prediction only];
158-244 1.58e-03

Gas vesicle protein YhaH [General function prediction only];


Pssm-ID: 444004 [Multi-domain]  Cd Length: 106  Bit Score: 37.26  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123 158 QKSEELRGNLEQSVKELQAQLEPYTAELKEKVDQHLQEFQETVSPLAEDLQVQIreraqivqqsltpyaEDLKEKLDPYA 237
Cdd:COG4980   27 KSGKETRKKLKDKADDLKDKAEDLKDELKEKASELSEEAKEKLDELIEEIKEKI---------------EELKEEVEPKI 91


                 ....*..
gi 119943123 238 QNLKDQL 244
Cdd:COG4980   92 EELKEEA 98
Apolipoprotein pfam01442
Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a ...
 166-254 7.34e-03

Apolipoprotein A1/A4/E domain; These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.


Pssm-ID: 460211 [Multi-domain]  Cd Length: 175  Bit Score: 36.47  E-value: 7.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119943123  166 NLEQSVKELQAqlepYTAELKEKVDQHLQEFQETVSPLAEDLQVQIRERAQIVQQSLTPYAEDLKEKLDPYAQNLKDQLI 245
Cdd:pfam01442   1 LLEDSLDELST----YAEELQEQLGPVAQELVDRLEKETEALRERLQKDLEEVRAKLEPYLEELQAKLGQNVEELRQRLE 76


                  ....*....
gi 119943123  246 SLYDSFTKR 254
Cdd:pfam01442  77 PYTEELRKR 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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