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Conserved domains on  [gi|114205446|ref|NP_001041525|]
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probable gluconokinase isoform b [Mus musculus]

Protein Classification

gluconokinase( domain architecture ID 1903940)

gluconokinase catalyzes the phosphoryl transfer from ATP to gluconate to form gluconate-6-phoshate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GntK super family cl42402
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-55 6.62e-31

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


The actual alignment was detected with superfamily member COG3265:

Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 105.98  E-value: 6.62e-31
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 114205446   4 PGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTD 52
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-55 6.62e-31

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 105.98  E-value: 6.62e-31
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 114205446   4 PGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTD 52
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 6-55 9.47e-24

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 87.31  E-value: 9.47e-24
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLND 50
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 7-55 7.07e-17

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 70.12  E-value: 7.07e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 114205446    7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:TIGR01313   1 FVLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLND 49
idnK PRK09825
gluconokinase;
3-56 9.19e-14

gluconokinase;


Pssm-ID: 182097  Cd Length: 176  Bit Score: 62.35  E-value: 9.19e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 114205446   3 APGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQ 56
Cdd:PRK09825   2 AGESYILMGVSGSGKSLIGSKIAALFSAKFIDGDDLHPAKNIDKMSQGIPLTDE 55
SKI pfam01202
Shikimate kinase;
14-48 1.60e-08

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 48.35  E-value: 1.60e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 114205446   14 GSGKSTVGALLASKLGWKFYDADDYHSEENRIKMA 48
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIA 36
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 4-29 8.25e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 33.12  E-value: 8.25e-03
                           10        20
                   ....*....|....*....|....*.
gi 114205446     4 PGVLLVMGVSGSGKSTVGALLASKLG 29
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELG 27
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-55 6.62e-31

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 105.98  E-value: 6.62e-31
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 114205446   4 PGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTD 52
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 6-55 9.47e-24

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 87.31  E-value: 9.47e-24
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLND 50
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 7-55 7.07e-17

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 70.12  E-value: 7.07e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 114205446    7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:TIGR01313   1 FVLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLND 49
idnK PRK09825
gluconokinase;
3-56 9.19e-14

gluconokinase;


Pssm-ID: 182097  Cd Length: 176  Bit Score: 62.35  E-value: 9.19e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 114205446   3 APGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQ 56
Cdd:PRK09825   2 AGESYILMGVSGSGKSLIGSKIAALFSAKFIDGDDLHPAKNIDKMSQGIPLTDE 55
gntK PRK11545
gluconokinase;
10-55 1.86e-11

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 56.26  E-value: 1.86e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 114205446  10 MGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSD 55
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLND 46
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 11-38 4.60e-10

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 52.44  E-value: 4.60e-10
                         10        20
                 ....*....|....*....|....*...
gi 114205446  11 GVSGSGKSTVGALLASKLGWKFYDADDY 38
Cdd:COG0703    5 GMMGAGKSTVGRLLAKRLGLPFVDTDAE 32
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 11-38 1.83e-09

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 50.63  E-value: 1.83e-09
                         10        20
                 ....*....|....*....|....*...
gi 114205446  11 GVSGSGKSTVGALLASKLGWKFYDADDY 38
Cdd:cd00464    6 GMMGAGKTTVGRLLAKALGLPFVDLDEL 33
SKI pfam01202
Shikimate kinase;
14-48 1.60e-08

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 48.35  E-value: 1.60e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 114205446   14 GSGKSTVGALLASKLGWKFYDADDYHSEENRIKMA 48
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIA 36
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-42 1.78e-08

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 47.87  E-value: 1.78e-08
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205446  11 GVSGSGKSTVGALLASKLGWKFYDADDYHSEE 42
Cdd:cd02020    6 GPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEE 37
aroK PRK00131
shikimate kinase; Reviewed
 1-37 2.84e-08

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 47.88  E-value: 2.84e-08
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 114205446   1 MEAPGVLLVmGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:PRK00131   2 LKGPNIVLI-GFMGAGKSTIGRLLAKRLGYDFIDTDH 37
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 1-31 5.44e-07

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 44.94  E-value: 5.44e-07
                         10        20        30
                 ....*....|....*....|....*....|.
gi 114205446   1 MEAPGVLLVMGVSGSGKSTVGALLASKLGWK 31
Cdd:COG2074    3 MKRPRIILIGGASGVGKSTIAAELARRLGIP 33
PRK06217 PRK06217
hypothetical protein; Validated
 7-38 2.49e-06

hypothetical protein; Validated


Pssm-ID: 168472  Cd Length: 183  Bit Score: 42.73  E-value: 2.49e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205446   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDY 38
Cdd:PRK06217   4 IHITGASGSGTTTLGAALAERLDIPHLDTDDY 35
aroL PRK03731
shikimate kinase AroL;
7-38 3.94e-06

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 42.24  E-value: 3.94e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205446   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDY 38
Cdd:PRK03731   5 LFLVGARGCGKTTVGMALAQALGYRFVDTDQW 36
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
13-34 4.34e-06

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 42.12  E-value: 4.34e-06
                         10        20
                 ....*....|....*....|..
gi 114205446  13 SGSGKSTVGALLASKLGWKFYD 34
Cdd:COG1102    9 PGSGGTTIAKRLAEKLGLPLYD 30
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
6-37 1.08e-05

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 41.05  E-value: 1.08e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDV 32
PRK13946 PRK13946
shikimate kinase; Provisional
 6-37 1.78e-05

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 40.29  E-value: 1.78e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205446   6 VLLVmGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:PRK13946  13 VVLV-GLMGAGKSTVGRRLATMLGLPFLDADT 43
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
11-34 2.73e-05

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 40.01  E-value: 2.73e-05
                         10        20
                 ....*....|....*....|....
gi 114205446  11 GVSGSGKSTVGALLASKLGWKFYD 34
Cdd:COG0283    7 GPAGSGKSTVAKALAKRLGYHYLD 30
PRK13949 PRK13949
shikimate kinase; Provisional
 7-46 7.12e-05

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 38.56  E-value: 7.12e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 114205446   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDYhsEENRIK 46
Cdd:PRK13949   4 IFLVGYMGAGKTTLGKALARELGLSFIDLDFF--IENRFH 41
PLN02199 PLN02199
shikimate kinase
 7-36 7.31e-05

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 39.30  E-value: 7.31e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 114205446   7 LLVMGVSGSGKSTVGALLASKLGWKFYDAD 36
Cdd:PLN02199 105 MYLVGMMGSGKTTVGKLMSKVLGYTFFDCD 134
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 11-34 9.60e-05

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 38.44  E-value: 9.60e-05
                          10        20
                  ....*....|....*....|....
gi 114205446   11 GVSGSGKSTVGALLASKLGWKFYD 34
Cdd:pfam02224   5 GPSGSGKSTVARILARKLGYKYLD 28
PRK04182 PRK04182
cytidylate kinase; Provisional
 9-37 1.18e-04

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 38.25  E-value: 1.18e-04
                         10        20
                 ....*....|....*....|....*....
gi 114205446   9 VMGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:PRK04182   5 ISGPPGSGKTTVARLLAEKLGLKHVSAGE 33
PRK05541 PRK05541
adenylylsulfate kinase; Provisional
 1-82 2.78e-04

adenylylsulfate kinase; Provisional


Pssm-ID: 235498  Cd Length: 176  Bit Score: 37.34  E-value: 2.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205446   1 MEAPGVLLVMGVSGSGKSTVGALLASKLGWK-----FYDADDY--------HSEENRIKMAK-----GVPLSDQrcGFGT 62
Cdd:PRK05541   4 KPNGYVIWITGLAGSGKTTIAKALYERLKLKysnviYLDGDELreilghygYDKQSRIEMALkraklAKFLADQ--GMIV 81

                         90       100
                 ....*....|....*....|.
gi 114205446  63 ACCS-SLFSSEENVQRHLDPR 82
Cdd:PRK05541  82 IVTTiSMFDEIYAYNRKHLPN 102
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
6-43 4.28e-04

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 36.72  E-value: 4.28e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEEN 43
Cdd:COG1936    2 RIAITGTPGTGKTTVAKLLAERLGLEVIHLNDLVKEEG 39
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 14-36 4.88e-04

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 36.58  E-value: 4.88e-04
                         10        20
                 ....*....|....*....|...
gi 114205446  14 GSGKSTVGALLAsKLGWKFYDAD 36
Cdd:COG0237   11 GSGKSTVARMFA-ELGAPVIDAD 32
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 4-32 6.60e-04

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 36.47  E-value: 6.60e-04
                         10        20
                 ....*....|....*....|....*....
gi 114205446   4 PGVLLVmGVSGSGKSTVGALLASKLGWKF 32
Cdd:PRK08154 134 RRIALI-GLRGAGKSTLGRMLAARLGVPF 161
PRK13947 PRK13947
shikimate kinase; Provisional
 11-36 8.77e-04

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 35.84  E-value: 8.77e-04
                         10        20
                 ....*....|....*....|....*.
gi 114205446  11 GVSGSGKSTVGALLASKLGWKFYDAD 36
Cdd:PRK13947   8 GFMGTGKTTVGKRVATTLSFGFIDTD 33
DPCK cd02022
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of ...
 14-38 1.94e-03

Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis.


Pssm-ID: 238980  Cd Length: 179  Bit Score: 34.80  E-value: 1.94e-03
                         10        20
                 ....*....|....*....|....*
gi 114205446  14 GSGKSTVGALLAsKLGWKFYDADDY 38
Cdd:cd02022    9 GSGKSTVAKLLK-ELGIPVIDADKI 32
PRK06547 PRK06547
hypothetical protein; Provisional
 6-39 2.26e-03

hypothetical protein; Provisional


Pssm-ID: 235825  Cd Length: 172  Bit Score: 34.72  E-value: 2.26e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYH 39
Cdd:PRK06547  17 TVLIDGRSGSGKTTLAGALAARTGFQLVHLDDLY 50
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 6-39 2.29e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 34.21  E-value: 2.29e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 114205446    6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYH 39
Cdd:pfam13671   1 LILLVGLPGSGKSTLARRLLEELGAVRLSSDDER 34
aroK PRK05057
shikimate kinase AroK;
7-37 2.30e-03

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 34.69  E-value: 2.30e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 114205446   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:PRK05057   7 IFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQ 37
Cytidylate_kin2 pfam13189
Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.
 14-36 2.32e-03

Cytidylate kinase-like family; This family includes enzymes related to cytidylate kinase.


Pssm-ID: 433023 [Multi-domain]  Cd Length: 176  Bit Score: 34.53  E-value: 2.32e-03
                          10        20
                  ....*....|....*....|...
gi 114205446   14 GSGKSTVGALLASKLGWKFYDAD 36
Cdd:pfam13189   9 GSGGTTIAKKLAEKLGYPFYDRE 31
AAA_18 pfam13238
AAA domain;
8-43 2.39e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 34.33  E-value: 2.39e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 114205446    8 LVMGVSGSGKSTVGALLASKLGWkFYDADDYHSEEN 43
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGF-GDNVRDLALENG 36
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 3-25 2.67e-03

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 34.38  E-value: 2.67e-03
                         10        20
                 ....*....|....*....|....
gi 114205446   3 APG-VLLVMGVSGSGKSTVGALLA 25
Cdd:COG4136   25 APGeILTLMGPSGSGKSTLLAAIA 48
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 4-28 3.45e-03

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 34.29  E-value: 3.45e-03
                         10        20
                 ....*....|....*....|....*
gi 114205446   4 PGVLLVMGVSGSGKSTVGALLASKL 28
Cdd:COG0529   16 GFVVWFTGLSGSGKSTLANALERRL 40
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
6-34 5.16e-03

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 33.87  E-value: 5.16e-03
                         10        20
                 ....*....|....*....|....*....
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWKFYD 34
Cdd:PRK11860 444 VICIDGPTASGKGTVAARVAEALGYHYLD 472
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 6-31 6.30e-03

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 33.36  E-value: 6.30e-03
                         10        20
                 ....*....|....*....|....*.
gi 114205446   6 VLLVMGVSGSGKSTVGALLASKLGWK 31
Cdd:cd01428    1 RILLLGPPGSGKGTQAERLAKKYGLP 26
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 4-29 8.25e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 33.12  E-value: 8.25e-03
                           10        20
                   ....*....|....*....|....*.
gi 114205446     4 PGVLLVMGVSGSGKSTVGALLASKLG 29
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELG 27
NK cd02019
Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of ...
 6-29 8.70e-03

Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates to nucleosides/nucleotides, nucleoside monophosphates, or sugars. Members of this family play a wide variety of essential roles in nucleotide metabolism, the biosynthesis of coenzymes and aromatic compounds, as well as the metabolism of sugar and sulfate.


Pssm-ID: 238977 [Multi-domain]  Cd Length: 69  Bit Score: 31.92  E-value: 8.70e-03
                        10        20
                ....*....|....*....|....
gi 114205446  6 VLLVMGVSGSGKSTVGALLASKLG 29
Cdd:cd02019   1 IIAITGGSGSGKSTVAKKLAEQLG 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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