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Conserved domains on  [gi|115533260|ref|NP_001041152|]
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G_PROTEIN_RECEP_F1_2 domain-containing protein [Caenorhabditis elegans]

Protein Classification

class D serpentine receptor( domain architecture ID 10563389)

class D serpentine receptor (Srd) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 21-312 4.21e-74

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402094  Cd Length: 292  Bit Score: 230.51  E-value: 4.21e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260   21 EIVYPIFLTITLIFHSVLLVFIIFFSPSHLNFLKFLLLTTSLLDVFATSILFYIQPRILSeYQVNVPVYCYGPCREMNTQ 100
Cdd:pfam10317   2 SIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIP-NGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260  101 FCFSLFMMWQTVSIAVGISLTYTLYFKYHKLNSKGPlfGWKLVRSLFLFYIPCLVSMCCAFVVVLRNVLPNEELNKESFS 180
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDP--KRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260  181 DTRIE-FTKIGNMKLGELPNRINFAMIAYAIYCSPIITFWFHWKTNKSLNNALSGSSPYLRYHAKNVMMGITIQVVMHFI 259
Cdd:pfam10317 159 NYNLTdYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLF 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 115533260  260 FYIPFFTLYSYSLLTGTKIFVQQFFMAMSPNLAASFDPLINLYFVVPYRTKIK 312
Cdd:pfam10317 239 SYIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAIL 291
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 21-312 4.21e-74

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 230.51  E-value: 4.21e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260   21 EIVYPIFLTITLIFHSVLLVFIIFFSPSHLNFLKFLLLTTSLLDVFATSILFYIQPRILSeYQVNVPVYCYGPCREMNTQ 100
Cdd:pfam10317   2 SIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIP-NGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260  101 FCFSLFMMWQTVSIAVGISLTYTLYFKYHKLNSKGPlfGWKLVRSLFLFYIPCLVSMCCAFVVVLRNVLPNEELNKESFS 180
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDP--KRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260  181 DTRIE-FTKIGNMKLGELPNRINFAMIAYAIYCSPIITFWFHWKTNKSLNNALSGSSPYLRYHAKNVMMGITIQVVMHFI 259
Cdd:pfam10317 159 NYNLTdYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLF 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 115533260  260 FYIPFFTLYSYSLLTGTKIFVQQFFMAMSPNLAASFDPLINLYFVVPYRTKIK 312
Cdd:pfam10317 239 SYIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAIL 291
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 21-312 4.21e-74

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 230.51  E-value: 4.21e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260   21 EIVYPIFLTITLIFHSVLLVFIIFFSPSHLNFLKFLLLTTSLLDVFATSILFYIQPRILSeYQVNVPVYCYGPCREMNTQ 100
Cdd:pfam10317   2 SIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIP-NGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260  101 FCFSLFMMWQTVSIAVGISLTYTLYFKYHKLNSKGPlfGWKLVRSLFLFYIPCLVSMCCAFVVVLRNVLPNEELNKESFS 180
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDP--KRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHP 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115533260  181 DTRIE-FTKIGNMKLGELPNRINFAMIAYAIYCSPIITFWFHWKTNKSLNNALSGSSPYLRYHAKNVMMGITIQVVMHFI 259
Cdd:pfam10317 159 NYNLTdYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLF 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 115533260  260 FYIPFFTLYSYSLLTGTKIFVQQFFMAMSPNLAASFDPLINLYFVVPYRTKIK 312
Cdd:pfam10317 239 SYIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAIL 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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