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Conserved domains on  [gi|115532756|ref|NP_001040894|]
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Sop-2-related protein 1 [Caenorhabditis elegans]

Protein Classification

PAT1 family protein( domain architecture ID 1001013)

PAT1 family protein similar to Saccharomyces cerevisiae DNA topoisomerase 2-associated protein PAT1, an activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation

Gene Ontology:  GO:0003723

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 279-521 1.28e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 42.33  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  279 EEASFEAEQPSPQVPQASIEGPSQQ-QQIPGTSQQKRQVARGSRTNMISYHDLPP-----------GTG---NAPPMACP 343
Cdd:pfam09770  98 EQVRFNRQQPAARAAQSSAQPPASSlPQYQYASQQSQQPSKPVRTGYEKYKEPEPipdlqvdaslwGVApkkAAAPAPAP 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  344 QVTlkleknvpfeAKIRAVAGYTRKPIS--EVQK-MR-----PSDLESIFHSICIASVQRIkrRNELVQQLQEINAQSCK 415
Cdd:pfam09770 178 QPA----------AQPASLPAPSRKMMSleEVEAaMRaqakkPAQQPAPAPAQPPAAPPAQ--QAQQQQQFPPQIQQQQQ 245

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  416 SPTMTMNKKFTLAKAY-----QRVQNEIEKIDREQILPQQYMNMPPMPPQGQQ--------RLPPPAYPPGILPPQQNRQ 482
Cdd:pfam09770 246 PQQQPQQPQQHPGQGHpvtilQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQptqilqnpNRLSAARVGYPQNPQPGVQ 325

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 115532756  483 QGVPPQFQRSPQFMiGPDGQRYAHP--YMQLpNSNQRARIL 521
Cdd:pfam09770 326 PAPAHQAHRQQGSF-GRQAPIITHPqqLAQL-SEEEKAAYL 364
 
Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 279-521 1.28e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 42.33  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  279 EEASFEAEQPSPQVPQASIEGPSQQ-QQIPGTSQQKRQVARGSRTNMISYHDLPP-----------GTG---NAPPMACP 343
Cdd:pfam09770  98 EQVRFNRQQPAARAAQSSAQPPASSlPQYQYASQQSQQPSKPVRTGYEKYKEPEPipdlqvdaslwGVApkkAAAPAPAP 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  344 QVTlkleknvpfeAKIRAVAGYTRKPIS--EVQK-MR-----PSDLESIFHSICIASVQRIkrRNELVQQLQEINAQSCK 415
Cdd:pfam09770 178 QPA----------AQPASLPAPSRKMMSleEVEAaMRaqakkPAQQPAPAPAQPPAAPPAQ--QAQQQQQFPPQIQQQQQ 245

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  416 SPTMTMNKKFTLAKAY-----QRVQNEIEKIDREQILPQQYMNMPPMPPQGQQ--------RLPPPAYPPGILPPQQNRQ 482
Cdd:pfam09770 246 PQQQPQQPQQHPGQGHpvtilQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQptqilqnpNRLSAARVGYPQNPQPGVQ 325

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 115532756  483 QGVPPQFQRSPQFMiGPDGQRYAHP--YMQLpNSNQRARIL 521
Cdd:pfam09770 326 PAPAHQAHRQQGSF-GRQAPIITHPqqLAQL-SEEEKAAYL 364
 
Name Accession Description Interval E-value
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 279-521 1.28e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 42.33  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  279 EEASFEAEQPSPQVPQASIEGPSQQ-QQIPGTSQQKRQVARGSRTNMISYHDLPP-----------GTG---NAPPMACP 343
Cdd:pfam09770  98 EQVRFNRQQPAARAAQSSAQPPASSlPQYQYASQQSQQPSKPVRTGYEKYKEPEPipdlqvdaslwGVApkkAAAPAPAP 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  344 QVTlkleknvpfeAKIRAVAGYTRKPIS--EVQK-MR-----PSDLESIFHSICIASVQRIkrRNELVQQLQEINAQSCK 415
Cdd:pfam09770 178 QPA----------AQPASLPAPSRKMMSleEVEAaMRaqakkPAQQPAPAPAQPPAAPPAQ--QAQQQQQFPPQIQQQQQ 245

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 115532756  416 SPTMTMNKKFTLAKAY-----QRVQNEIEKIDREQILPQQYMNMPPMPPQGQQ--------RLPPPAYPPGILPPQQNRQ 482
Cdd:pfam09770 246 PQQQPQQPQQHPGQGHpvtilQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQptqilqnpNRLSAARVGYPQNPQPGVQ 325

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 115532756  483 QGVPPQFQRSPQFMiGPDGQRYAHP--YMQLpNSNQRARIL 521
Cdd:pfam09770 326 PAPAHQAHRQQGSF-GRQAPIITHPqqLAQL-SEEEKAAYL 364
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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