|
Name |
Accession |
Description |
Interval |
E-value |
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
525-1088 |
3.13e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 3.13e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 525 VSQESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHREEMAlkgKDAAEAVLEAFRAhASQRISQLEQGITSVQEfrg 604
Cdd:COG1196 237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL---ELELEEAQAEEYE-LLAELARLEQDIARLEE--- 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 605 LLQEAQTQLIGLHTEQEELAQHTVSLTSALQQdwtsvqqnygtWAALLSRSRELTKKLTAKSRQALQERDAAIEEKDQVV 684
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELEELEEELEE-----------LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 685 KEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHShcvQDLAMKDELLCQLTQSNKEQAAQw 764
Cdd:COG1196 379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA---ELEEEEEEEEEALEEAAEEEAEL- 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 765 QKEETELKHRQAELLQQKAVLAKEVQDLRETmefVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAE 844
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEE---LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 845 LASTEAKHEQQALEKTHQHskELCLLAEQLQSLTLFLEAkleeNKAESDIILPSTGCAPAQEHPPSSDSSVSEQIPTAV- 923
Cdd:COG1196 532 VEAAYEAALEAALAAALQN--IVVEDDEVAAAAIEYLKA----AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVa 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 924 VDEVPEPAPVPLLGSVKSAFTRVASTAPFRPTETPALEKSLAEMSAVLQELQRLCALLQESKEEAVGVLQREICELHTRL 1003
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1004 QAQEEEHQEAQKAKEADIEKLNQALCLRHKNEKELLEVIQKQNEKILGQIDTSGQLINLREEVTQLTRLLRRAETETKVL 1083
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
|
....*
gi 112984402 1084 QEALE 1088
Cdd:COG1196 766 ERELE 770
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
650-894 |
2.48e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.97 E-value: 2.48e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 650 ALLSRSRELTKKLTAKSRQALQERDAAIEEK-DQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENE 728
Cdd:COG1196 217 ELKEELKELEAELLLLKLRELEAELEELEAElEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 729 LKELQSQHSHCVQDLAMKDELLcqltQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHL 808
Cdd:COG1196 297 LARLEQDIARLEERRRELEERL----EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 809 ELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALEKTHQHSKELCLLAEQLQSLTLFLEAKLEEN 888
Cdd:COG1196 373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452
|
....*.
gi 112984402 889 KAESDI 894
Cdd:COG1196 453 ELEEEE 458
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
546-1093 |
2.01e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.89 E-value: 2.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 546 LRAKLQSLKTEWEEA-RHRE-EMALKGKDAAEAVL--EAFRAHASQRISQLEQGITSVQEFRGLLQEAQTQLiglhtEQE 621
Cdd:COG1196 198 LERQLEPLERQAEKAeRYRElKEELKELEAELLLLklRELEAELEELEAELEELEAELEELEAELAELEAEL-----EEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 622 ELAQHTVSLTSALQQdwtsvqqnygtwAALLSRSRELTKKLTAKSRQALQERDAAiEEKDQVVKEVEQVSAHLEDCKGQI 701
Cdd:COG1196 273 RLELEELELELEEAQ------------AEEYELLAELARLEQDIARLEERRRELE-ERLEELEEELAELEEELEELEEEL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 702 EQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLamkdellcqltQSNKEQAAQWQKEETELKHRQAELLQQ 781
Cdd:COG1196 340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL-----------EELAEELLEALRAAAELAAQLEELEEA 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 782 KAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALEKTH 861
Cdd:COG1196 409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 862 QHSKELCLLAEQLQSLTLFLEAKLEENKAESDII-----------------LPSTGCAPAQEHPPSSDSSVSEQI----- 919
Cdd:COG1196 489 AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligveaayeaaLEAALAAALQNIVVEDDEVAAAAIeylka 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 920 ---------PTAVVDEVPEPAPVPLLGSVKSAFTRVASTAPFRPTETPALEKSLAE-------MSAVLQELQRLCALLQE 983
Cdd:COG1196 569 akagratflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGrtlvaarLEAALRRAVTLAGRLRE 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 984 SKEEAVGVLQREICELHTRLQAQEEEHQEAQKAKEADIEKLNQALCLRHKNEKELLEVIQKQNEKILGQIDTSGQLINLR 1063
Cdd:COG1196 649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728
|
570 580 590
....*....|....*....|....*....|
gi 112984402 1064 EEVTQLTRLLRRAETETKVLQEALEGQVDP 1093
Cdd:COG1196 729 QLEAEREELLEELLEEEELLEEEALEELPE 758
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
542-1184 |
3.44e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.24 E-value: 3.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 542 VLKKLRAKLQSLKTEWEEA----RHREEMALKGKDAAEAVLEAFRAHASQRISQLEQGITSVQEFRGLLQEAQTQLIGLH 617
Cdd:TIGR02168 194 ILNELERQLKSLERQAEKAerykELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 618 TEQEEL------AQHTVSLTSALQQDwtsVQQNYGTWAALLSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVS 691
Cdd:TIGR02168 274 LEVSELeeeieeLQKELYALANEISR---LEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 692 AHLEDCKGQIEQL--KLENSRLT-ADLSAQLQTLASTENELKELQSQHSHCVQDLamkDELLCQLTQSNKEQAAQWQKEE 768
Cdd:TIGR02168 351 EELESLEAELEELeaELEELESRlEELEEQLETLRSKVAQLELQIASLNNEIERL---EARLERLEDRRERLQQEIEELL 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 769 TEL-KHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLR----- 842
Cdd:TIGR02168 428 KKLeEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfseg 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 843 ------------------AELASTEAKHEQqALEKThqhskelclLAEQLQSLTLFLEAK-------LEENKAESDIILP 897
Cdd:TIGR02168 508 vkallknqsglsgilgvlSELISVDEGYEA-AIEAA---------LGGRLQAVVVENLNAakkaiafLKQNELGRVTFLP 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 898 STGCAPAQehPPSSDSSVSEQIPTAV---VDEVPEPAPVPLLGSVKSAFTRVASTapfrPTETPALEKSL-AEMSAVLQE 973
Cdd:TIGR02168 578 LDSIKGTE--IQGNDREILKNIEGFLgvaKDLVKFDPKLRKALSYLLGGVLVVDD----LDNALELAKKLrPGYRIVTLD 651
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 974 LQRLC---ALLQESKEEAVGVLQR--EICELHTRLQAQEEEHQEAQKAKEADIEKLNQALCLRHKNEKELLEVIQKQNEk 1048
Cdd:TIGR02168 652 GDLVRpggVITGGSAKTNSSILERrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA- 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1049 ilgqidTSGQLINLREEVTQLTRLLRRAETETKVLQEALEGQVDPSCQLMATNWIQEKVF---------LSQEVNKLRAM 1119
Cdd:TIGR02168 731 ------LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIeeleaqieqLKEELKALREA 804
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 1120 FLEVKNEKKQLMDKYLSHRHILEENLRRSDTELKKLDDTIQHIYETLLSIPEVVKSCKELQGLLE 1184
Cdd:TIGR02168 805 LDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
649-851 |
4.49e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 62.86 E-value: 4.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 649 AALLSRSRELTKKL--TAKSRQALQERDAAIEEK-DQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLA-- 723
Cdd:COG4942 30 EQLQQEIAELEKELaaLKKEEKALLKQLAALERRiAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAel 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 724 -------STENELKELQSQHShcVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETM 796
Cdd:COG4942 110 lralyrlGRQPPLALLLSPED--FLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEER 187
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 797 EFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAK 851
Cdd:COG4942 188 AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
586-887 |
6.98e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 6.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 586 SQRISQLEQGITSVQEfrgLLQEAQTQLIGLHTEQEELAQHTVSLTSALQQDWTSVQQNYGTWAALLSRSRELTKKLT-- 663
Cdd:TIGR02168 676 RREIEELEEKIEELEE---KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAql 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 664 ----AKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDckgQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHC 739
Cdd:TIGR02168 753 skelTELEAEIEELEERLEEAEEELAEAEAEIEELEA---QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 740 VQDLAMKDELLCQLTQsnkeQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKA 819
Cdd:TIGR02168 830 ERRIAATERRLEDLEE----QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE 905
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 112984402 820 TLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALEKTHQHSKELcLLAEQLQSLTLFLEAKLEE 887
Cdd:TIGR02168 906 LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL-EEAEALENKIEDDEEEARR 972
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
525-827 |
1.02e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 525 VSQESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAVLEAFRahasQRISQLEQGITSVQEfrg 604
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQLSK--- 754
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 605 LLQEAQTQLIGLHTEQEELAQHTVSLTSALQQDWTSVQQNYGTWAALLSRSRELTKKLTAKSRQALQERdaaiEEKDQVV 684
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR----ERLESLE 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 685 KEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQW 764
Cdd:TIGR02168 831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKR 910
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 112984402 765 QKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRER 827
Cdd:TIGR02168 911 SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRR 973
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
426-826 |
1.36e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.77 E-value: 1.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 426 DLEENLLNALVLLEVLSHQLQAWKSQLTVPSRQAQDSSTQTDSSAAVVTKTPKHLQDSKEIRQALLQARNVIHSWGLVSR 505
Cdd:TIGR02168 688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 506 DLMSLLHLSLTHVQDDRVTVSQESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAVLEAfrahA 585
Cdd:TIGR02168 768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED----L 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 586 SQRISQLEQGITSVQEFRGLLQEAQTQLiglhteQEELAQHTVSLTSALQQdwtsvqqnygtwaalLSRSRELTKKLTAK 665
Cdd:TIGR02168 844 EEQIEELSEDIESLAAEIEELEELIEEL------ESELEALLNERASLEEA---------------LALLRSELEELSEE 902
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 666 SRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKlenSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAM 745
Cdd:TIGR02168 903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ---ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 746 KdelLCQLTQSNKEQAAQWQkeetELKHRQAELLQQKAVLAKEVQDLRETMEFVDEEsqvahlelgqIESQLKATLEVLR 825
Cdd:TIGR02168 980 K---IKELGPVNLAAIEEYE----ELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE----------ARERFKDTFDQVN 1042
|
.
gi 112984402 826 E 826
Cdd:TIGR02168 1043 E 1043
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
524-1155 |
7.92e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.08 E-value: 7.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 524 TVSQESQRAETLVSSCSRVLKKLRA------KLQSLKTEWEEAR-----HREEMALKGKDAAEAVLEAFRAHASQRISQL 592
Cdd:TIGR02169 181 EVEENIERLDLIIDEKRQQLERLRRerekaeRYQALLKEKREYEgyellKEKEALERQKEAIERQLASLEEELEKLTEEI 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 593 EQGITSVQEFRGLLQEAQTQLIGLHTE-----QEELAQHTVSLTSA----------LQQDWTSVQQNYGTWAALLSRSRE 657
Cdd:TIGR02169 261 SELEKRLEEIEQLLEELNKKIKDLGEEeqlrvKEKIGELEAEIASLersiaekereLEDAEERLAKLEAEIDKLLAEIEE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 658 LTKKLT--AKSRQALQER-DAAIEEKDQVVKEVEQVSA--------------HLEDCKGQIEQLKLENSRLTADLSAQLQ 720
Cdd:TIGR02169 341 LEREIEeeRKRRDKLTEEyAELKEELEDLRAELEEVDKefaetrdelkdyreKLEKLKREINELKRELDRLQEELQRLSE 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 721 TLASTENELKELQSQHshcvqdLAMKDELlcqltqsnKEQAAQWQKEETELKhrqaELLQQKAVLAKEVQDLRETMEFVD 800
Cdd:TIGR02169 421 ELADLNAAIAGIEAKI------NELEEEK--------EDKALEIKKQEWKLE----QLAADLSKYEQELYDLKEEYDRVE 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 801 EESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVE---SLRAELASTEAKHeQQALE------------KTHQHSK 865
Cdd:TIGR02169 483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERY-ATAIEvaagnrlnnvvvEDDAVAK 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 866 ELC--LLAEQLQSLTLFLEAKLEENKAESDIILPSTGCAPAQ---EHPPSSDSSVSEQIPTAVVDEVPEPAPvPLLGSVK 940
Cdd:TIGR02169 562 EAIelLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVdlvEFDPKYEPAFKYVFGDTLVVEDIEAAR-RLMGKYR 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 941 ------------SAFTRVASTAPFRPTETPALEKSLAEMSAVLQELQRLCALLQESKEE----------AVGVLQREICE 998
Cdd:TIGR02169 641 mvtlegelfeksGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRienrldelsqELSDASRKIGE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 999 LHTRLQAQEEEHQ---EAQKAKEADIEKLNQALCLRHKNEKELLEVIQKQNEKIlgqidtsgqlINLREEVTQLTRLLRR 1075
Cdd:TIGR02169 721 IEKEIEQLEQEEEklkERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL----------HKLEEALNDLEARLSH 790
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1076 AETETKV--LQEALEGQVDPSCQLMATNWI-----QEKVFLSQEVNKLRAMFLEVKNEKKQLMDKYlshrHILEENLRRS 1148
Cdd:TIGR02169 791 SRIPEIQaeLSKLEEEVSRIEARLREIEQKlnrltLEKEYLEKEIQELQEQRIDLKEQIKSIEKEI----ENLNGKKEEL 866
|
....*..
gi 112984402 1149 DTELKKL 1155
Cdd:TIGR02169 867 EEELEEL 873
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
654-1147 |
1.97e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.63 E-value: 1.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 654 RSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQ--LQTLASTENELKE 731
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLplYQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 732 LQSQhshcvqdlamKDELlcqltqsnKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELG 811
Cdd:COG4717 144 LPER----------LEEL--------EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQ 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 812 QIESQLKATLEVLRERslqcetlkdtVESLRAELASTEAKHEQQALEKTHQHSKELCLLAEQLQSLTLFLEAKLEENKAE 891
Cdd:COG4717 206 QRLAELEEELEEAQEE----------LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTI 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 892 SDIILPSTGCAPAQehppSSDSSVSEQIPTAVVDEVPEPAPVPLLGS--VKSAFTRVASTAPFRPTETPALEKSLAEMSA 969
Cdd:COG4717 276 AGVLFLVLGLLALL----FLLLAREKASLGKEAEELQALPALEELEEeeLEELLAALGLPPDLSPEELLELLDRIEELQE 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 970 VLQELQRLC--ALLQESKEEAVGVLQREICELHTRLQAQEEEHQEAQKAKEAdIEKLNQALCLRHKNEKELLEVIQKQne 1047
Cdd:COG4717 352 LLREAEELEeeLQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEE-LEELEEQLEELLGELEELLEALDEE-- 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1048 kilgqidtsgqliNLREEVTQLTRLLRRAETETKVLQEALEgqvdpscqlmATNWIQEKVFLSQEVNKLRAMFLEVKNEK 1127
Cdd:COG4717 429 -------------ELEEELEELEEELEELEEELEELREELA----------ELEAELEQLEEDGELAELLQELEELKAEL 485
|
490 500
....*....|....*....|...
gi 112984402 1128 KQLMDKYLSHR---HILEENLRR 1147
Cdd:COG4717 486 RELAEEWAALKlalELLEEAREE 508
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
572-1087 |
7.96e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.85 E-value: 7.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 572 DAAEAVLEAF----RAH-----ASQRISQLEQGITSVQEFRGLLQEAQtqliglhtEQEELAqhtvsltsALQQDWTSvQ 642
Cdd:COG4913 225 EAADALVEHFddleRAHealedAREQIELLEPIRELAERYAAARERLA--------ELEYLR--------AALRLWFA-Q 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 643 QNYGTWAALLSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVS-AHLEDCKGQIEQLKLENSRLT---ADLSAQ 718
Cdd:COG4913 288 RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERErrrARLEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 719 LQTL----ASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRE 794
Cdd:COG4913 368 LAALglplPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRD 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 795 tmefvdeesQVAHlELGQIESQLKAT---LEVLRErslqCETLKDTVESLRAELAST---EAKHEQQALEKTHQHSkelc 868
Cdd:COG4913 448 ---------ALAE-ALGLDEAELPFVgelIEVRPE----EERWRGAIERVLGGFALTllvPPEHYAAALRWVNRLH---- 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 869 lLAEQLQsltlFLEAKLEENKAESDIILPST--GCAPAQEHPPSS--DSSVSEQIPTAVVDEVPE----PAPVPLLGSVK 940
Cdd:COG4913 510 -LRGRLV----YERVRTGLPDPERPRLDPDSlaGKLDFKPHPFRAwlEAELGRRFDYVCVDSPEElrrhPRAITRAGQVK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 941 SAFTRVASTAPFRPTETP------------------ALEKSLAEMSAVLQELQRLCALLQESKEEAVGVLQR-----EIC 997
Cdd:COG4913 585 GNGTRHEKDDRRRIRSRYvlgfdnraklaaleaelaELEEELAEAEERLEALEAELDALQERREALQRLAEYswdeiDVA 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 998 ELHTRLQAQEEEHQEAQKAKeADIEKLNQALCLRHKNEKELLEVIQKQNEKIlGQIDTsgQLINLREEVTQLTRLLRRAE 1077
Cdd:COG4913 665 SAEREIAELEAELERLDASS-DDLAALEEQLEELEAELEELEEELDELKGEI-GRLEK--ELEQAEEELDELQDRLEAAE 740
|
570
....*....|
gi 112984402 1078 TETKVLQEAL 1087
Cdd:COG4913 741 DLARLELRAL 750
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
441-884 |
1.15e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 56.52 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 441 LSHQLQAWKSQLTVPSRQAQDSSTQTDSSAAVVTKTPKHLQDSKEIRQALLQARNVI-------HSWGLVSRDLMSLLHL 513
Cdd:TIGR00618 377 LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQelqqryaELCAAAITCTAQCEKL 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 514 SLTHVQDDRVTVSQESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAVLE--AFRAHASQRISQ 591
Cdd:TIGR00618 457 EKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNpgPLTRRMQRGEQT 536
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 592 LEQGITSVQEFRGLLQEAQTQLIGLhTEQEELAQHTvslTSALQQDWTSVQQNYGTWAALLSRSRELTKKLtAKSRQALQ 671
Cdd:TIGR00618 537 YAQLETSEEDVYHQLTSERKQRASL-KEQMQEIQQS---FSILTQCDNRSKEDIPNLQNITVRLQDLTEKL-SEAEDMLA 611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 672 ERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQ-------------LQTLASTENELKELQSQHSH 738
Cdd:TIGR00618 612 CEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQErvrehalsirvlpKELLASRQLALQKMQSEKEQ 691
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 739 CVQD---LAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIES 815
Cdd:TIGR00618 692 LTYWkemLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVT 771
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 112984402 816 QLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALEKTHQHSKELCLLAEQLQSLTLFLEAK 884
Cdd:TIGR00618 772 AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEK 840
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
542-893 |
3.26e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 54.66 E-value: 3.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 542 VLKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAVLEAFRaHASQRISQLEQGITSVQE-----------FRGLLQEAQ 610
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHE-ERREELETLEAEIEDLREtiaeterereeLAEEVRDLR 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 611 TQLIGLHTEQEELA---------QHTVSL-TSALQQDWTSVQQNYGTWAALLSRSRELTKKLTAKSRQALQERDAAIEEK 680
Cdd:PRK02224 286 ERLEELEEERDDLLaeaglddadAEAVEArREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 681 DQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELLcQLTQSNKEQ 760
Cdd:PRK02224 366 AELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATL-RTARERVEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 761 AAQWQK-----------EETELKHRQAELLQQKAVLAKEVQDLRETMEFVD------EESQVAHLELGQIESQLKATLEV 823
Cdd:PRK02224 445 AEALLEagkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEerleraEDLVEAEDRIERLEERREDLEEL 524
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 824 LRERSLQCETLKDTVESLRAELASTEAKHEQQALEKTHQHSKelcllAEQLQSLTLFLEAKLEENKAESD 893
Cdd:PRK02224 525 IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEE-----AEEAREEVAELNSKLAELKERIE 589
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
521-891 |
1.27e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 52.73 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 521 DRVTVSQESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHR----EEMALKGKDAA---EAVLEAFRAHASQRISQLE 593
Cdd:PRK02224 308 DAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDaddlEERAEELREEAaelESELEEAREAVEDRREEIE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 594 QGITSVQEFRGLLQEAQTQLIGLHTEQEELAQHtvsltsalqqdwtsvqqnygtwaalLSRSRELTKKLTAK---SRQAL 670
Cdd:PRK02224 388 ELEEEIEELRERFGDAPVDLGNAEDFLEELREE-------------------------RDELREREAELEATlrtARERV 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 671 QERDAAIEEKD-----QVVKEVEQVSAhLEDCKGQIEQLKLEnsrlTADLSAQLQTLASTENELKELQSQHSHcVQDLAM 745
Cdd:PRK02224 443 EEAEALLEAGKcpecgQPVEGSPHVET-IEEDRERVEELEAE----LEDLEEEVEEVEERLERAEDLVEAEDR-IERLEE 516
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 746 KDELLCQLTQSNKEQAaqwqkEETELkhRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLkATLEVLR 825
Cdd:PRK02224 517 RREDLEELIAERRETI-----EEKRE--RAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL-AELKERI 588
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 112984402 826 ERSLQCETLKDTVESLRAELASTEAKHEQQAlEKTHQHSKELCLLAEQLQSltlfLEAKLEENKAE 891
Cdd:PRK02224 589 ESLERIRTLLAAIADAEDEIERLREKREALA-ELNDERRERLAEKRERKRE----LEAEFDEARIE 649
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
598-850 |
1.90e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 598 SVQEFRGLLQEAQTQLIGLHTEQEELAQHTVSLTSALQQDWTSVQQNYGTWAAL---LSRSRELTKKLTAKSRQALQERD 674
Cdd:TIGR02169 675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLeqeEEKLKERLEELEEDLSSLEQEIE 754
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 675 AAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSR-----LTADLSAQLQTLASTENELKELQSQhshcVQDLAMKDEL 749
Cdd:TIGR02169 755 NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHsripeIQAELSKLEEEVSRIEARLREIEQK----LNRLTLEKEY 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 750 LCQLTQSNKEQAAQWQ-------KEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIES---QLKA 819
Cdd:TIGR02169 831 LEKEIQELQEQRIDLKeqiksieKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERkieELEA 910
|
250 260 270
....*....|....*....|....*....|.
gi 112984402 820 TLEVLRERSLQcetLKDTVESLRAELASTEA 850
Cdd:TIGR02169 911 QIEKKRKRLSE---LKAKLEALEEELSEIED 938
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
506-859 |
2.63e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 51.43 E-value: 2.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 506 DLMSLLHLSLTHVQDDRVTVSQESQRAETLVSSCSRVLKKLRAKLQSL--KTEWEEARHREEMALKGKDAAE-AVLEAFR 582
Cdd:pfam07888 45 ELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSreKHEELEEKYKELSASSEELSEEkDALLAQR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 583 AHASQRISQLEQGITSVQEfRGLLQEaqtqliglhTEQEELAQHTVSLTSALQQDWTSVQQNYGTWAALLSRSRELTKKL 662
Cdd:pfam07888 125 AAHEARIRELEEDIKTLTQ-RVLERE---------TELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEF 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 663 TaKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQD 742
Cdd:pfam07888 195 Q-ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAE 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 743 LAMKD----ELLCQLTQSN---KEQAAQWQKEETELKhRQAELLQQK-AVLAKEVQDLRETMEFVDEESQVAHLELGQie 814
Cdd:pfam07888 274 LHQARlqaaQLTLQLADASlalREGRARWAQERETLQ-QSAEADKDRiEKLSAELQRLEERLQEERMEREKLEVELGR-- 350
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 112984402 815 sqlkatlEVLRERSLQCETLKDTVEsLRAELASTEAKHEQQALEK 859
Cdd:pfam07888 351 -------EKDCNRVQLSESRRELQE-LKASLRVAQKEKEQLQAEK 387
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
710-1028 |
3.03e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 51.60 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 710 RLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETElkhrQAELLQQKAVLAKEV 789
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE----VEQLEERIAQLSKEL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 790 QDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHeQQALEKTHQHSKELCL 869
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEA-ANLRERLESLERRIAA 835
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 870 LAEQLQsltlFLEAKLEENKAESDIIlpstgcAPAQEHPPSSDSSVSEQIptavvdevpepapVPLLGSVKSAFTRVASt 949
Cdd:TIGR02168 836 TERRLE----DLEEQIEELSEDIESL------AAEIEELEELIEELESEL-------------EALLNERASLEEALAL- 891
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 950 apfRPTETPALEKSLAEMSAVLQELQRLCALLQESKEEAVGVLQR---EICELHTRLQAQEEEHQEAQKAKEADIEKLNQ 1026
Cdd:TIGR02168 892 ---LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGlevRIDNLQERLSEEYSLTLEEAEALENKIEDDEE 968
|
..
gi 112984402 1027 AL 1028
Cdd:TIGR02168 969 EA 970
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
678-914 |
5.33e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.59 E-value: 5.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 678 EEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAqLQTlastenELKELQSQHSHCVQDLAMKDELLcqltqSN 757
Cdd:pfam10174 268 EDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLA-LQT------KLETLTNQNSDCKQHIEVLKESL-----TA 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 758 KEQ-AAQWQKEETELKHRQAE--------------LLQQKAVLAKEVQDLRETMEFVDEESQVAHlelGQIESqlkaTLE 822
Cdd:pfam10174 336 KEQrAAILQTEVDALRLRLEEkesflnkktkqlqdLTEEKSTLAGEIRDLKDMLDVKERKINVLQ---KKIEN----LQE 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 823 VLRERSLQCETLKDTVESLRAELASTE---AKHEQQALEK-------THQHSKELCLLAEQLQSLTLFL-EAKLEENKAE 891
Cdd:pfam10174 409 QLRDKDKQLAGLKERVKSLQTDSSNTDtalTTLEEALSEKeriierlKEQREREDRERLEELESLKKENkDLKEKVSALQ 488
|
250 260
....*....|....*....|...
gi 112984402 892 SDIILPSTGCAPAQEHPPSSDSS 914
Cdd:pfam10174 489 PELTEKESSLIDLKEHASSLASS 511
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
543-1186 |
7.36e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 50.36 E-value: 7.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 543 LKKLRAKLQSLKTE----WEEARHREEMALKGKDAAEAVLEafrahasQRISQLEQGITSVQEFRGLLQEAQTQLIGLHT 618
Cdd:pfam02463 175 LKKLIEETENLAELiidlEELKLQELKLKEQAKKALEYYQL-------KEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 619 EQEELAQHTVSLTSALQQDWTSVQQNYgtwaALLSRSRELTKKLtaksrQALQERDAAIEEKDQVVKEVEQVSAHledck 698
Cdd:pfam02463 248 DEQEEIESSKQEIEKEEEKLAQVLKEN----KEEEKEKKLQEEE-----LKLLAKEEEELKSELLKLERRKVDDE----- 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 699 GQIEQLKLENSRLTADLSAQLQTLASTENELKELQ---SQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQ 775
Cdd:pfam02463 314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEikrEAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 776 AELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAEL--ASTEAKHE 853
Cdd:pfam02463 394 EEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDelELKKSEDL 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 854 QQALEKTHQHSKELCLLAEQLQSLTLFLEAKLEENKAESDIILPST------GCAPAQEHPPSSDSSVSEQIPTAVVDEV 927
Cdd:pfam02463 474 LKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGvggriiSAHGRLGDLGVAVENYKVAISTAVIVEV 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 928 PEPA-PVPLLGSVKSAFTRVASTAPFRPTETPALEKSLAEMSAVLQELQRLCALLQESKEEAVGVLQREICELHTRLQAQ 1006
Cdd:pfam02463 554 SATAdEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTE 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1007 EEEHQEAQKAKEADIEK---LNQALCLRHKNEKELLEVIQKQNEKILGQIDTSGQLINLREEVTQLT--RLLRRAETETK 1081
Cdd:pfam02463 634 LTKLKESAKAKESGLRKgvsLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEikKKEQREKEELK 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1082 VLQEALEGQVDPSCQLMATNwIQEKVFLSQEVNKLRAMFLEVKNEKKQLMDKYLSHRhILEENLRRSDTELKKLDDTIQH 1161
Cdd:pfam02463 714 KLKLEAEELLADRVQEAQDK-INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL-SLKEKELAEEREKTEKLKVEEE 791
|
650 660
....*....|....*....|....*
gi 112984402 1162 IYETLLSIPEVVKSCKELQGLLEFL 1186
Cdd:pfam02463 792 KEEKLKAQEEELRALEEELKEEAEL 816
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
543-854 |
8.98e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 8.98e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 543 LKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAV--LEAFRAHASQRISQLEQGITSVQEFRGLLQEAQTQLIGLHTEQ 620
Cdd:COG4717 97 LEELEEELEELEAELEELREELEKLEKLLQLLPLYqeLEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQ 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 621 EELAQHTVSLTSALQQDWTSVQQNYGTWAALLSRSRELTKKLTAKsRQALQERDAAIEEKDQVVKEVEQVSAHLED---- 696
Cdd:COG4717 177 EELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE-LEELEEELEQLENELEAAALEERLKEARLLllia 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 697 --------------------------CKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELL 750
Cdd:COG4717 256 aallallglggsllsliltiagvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLS 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 751 CQLTQSNKEQAAQWQKEETELKHRQAELLQQkaVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRER--- 827
Cdd:COG4717 336 PEELLELLDRIEELQELLREAEELEEELQLE--ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQlee 413
|
330 340 350
....*....|....*....|....*....|....*..
gi 112984402 828 ----------SLQCETLKDTVESLRAELASTEAKHEQ 854
Cdd:COG4717 414 llgeleelleALDEEELEEELEELEEELEELEEELEE 450
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
662-895 |
1.79e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 662 LTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQhshcvq 741
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE------ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 742 dlamkdellcqLTQSNKEQAAQwqkeETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQ--VAHLE-LGQIESQLK 818
Cdd:COG4942 85 -----------LAELEKEIAEL----RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLdaVRRLQyLKYLAPARR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 819 ATLEVLRERSLQCETLKDTVESLRAELAS--TEAKHEQQALEKTH-QHSKELCLLAEQLQSLTLFLEAKLEENKAESDII 895
Cdd:COG4942 150 EQAEELRADLAELAALRAELEAERAELEAllAELEEERAALEALKaERQKLLARLEKELAELAAELAELQQEAEELEALI 229
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
519-838 |
2.01e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.91 E-value: 2.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 519 QDDRVTVSQESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHREEmalkgkdAAEAVLEAFRAhasqRISQLEQGITS 598
Cdd:TIGR02169 687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEE-------KLKERLEELEE----DLSSLEQEIEN 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 599 V----QEFRGLLQEAQTQLIGLHTEQEELAQHTvsltsaLQQDWTSVQQnygtwaaLLSRSRELTKKLTAKSRQALQERD 674
Cdd:TIGR02169 756 VkselKELEARIEELEEDLHKLEEALNDLEARL------SHSRIPEIQA-------ELSKLEEEVSRIEARLREIEQKLN 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 675 AAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDlamKDELLCQLT 754
Cdd:TIGR02169 823 RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE---RDELEAQLR 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 755 Q-SNKEQAAQWQKEEteLKHRQAELLQQKAVLAKEVQDLR------------------------------ETMEFVD--- 800
Cdd:TIGR02169 900 ElERKIEELEAQIEK--KRKRLSELKAKLEALEEELSEIEdpkgedeeipeeelsledvqaelqrveeeiRALEPVNmla 977
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 112984402 801 ----EESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTV 838
Cdd:TIGR02169 978 iqeyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
657-914 |
2.16e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 48.80 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 657 ELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLAsteNELKELQSQH 736
Cdd:COG5185 218 ESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENA---NNLIKQFENT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 737 SHCVQDlAMKDELLCQLTQSNKEQAAQWQKE---ETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEEsqVAHLELGQI 813
Cdd:COG5185 295 KEKIAE-YTKSIDIKKATESLEEQLAAAEAEqelEESKRETETGIQNLTAEIEQGQESLTENLEAIKEE--IENIVGEVE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 814 ESQLKATLevlrerslqcETLKDTVESLRAELASTEAKHEQQALEKTHQHSKELCLLAEQLQSLTLFLEAKLEENKAESD 893
Cdd:COG5185 372 LSKSSEEL----------DSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSK 441
|
250 260
....*....|....*....|.
gi 112984402 894 IILPSTGCAPAQEHPPSSDSS 914
Cdd:COG5185 442 LLNELISELNKVMREADEESQ 462
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
652-858 |
2.50e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 652 LSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLA-------- 723
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGeraralyr 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 724 --STENELKELQSQHShcVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDE 801
Cdd:COG3883 98 sgGSVSYLDVLLGSES--FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 112984402 802 ESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALE 858
Cdd:COG3883 176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
633-852 |
3.99e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 3.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 633 ALQQDWTSVQQNYGTwaalLSRSRELTKKLTAKsRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLEnsRLT 712
Cdd:COG4913 222 DTFEAADALVEHFDD----LERAHEALEDAREQ-IELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLE--LLE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 713 ADLSAQLQTLASTENELKELQSQHSHCVQDLamkDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDL 792
Cdd:COG4913 295 AELEELRAELARLEAELERLEARLDALREEL---DELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL 371
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 793 RETM-----EFVDEESQVAHLeLGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKH 852
Cdd:COG4913 372 GLPLpasaeEFAALRAEAAAL-LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
656-895 |
4.14e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 4.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 656 RELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQ-IEQLKLENSRLTADLSAQLQTLASTENELKELQS 734
Cdd:pfam02463 172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKeKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 735 QHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKavlaKEVQDLRETMEFVDEESQVAHLELGQIE 814
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK----SELLKLERRKVDDEEKLKESEKEKKKAE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 815 SQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEqQALEKTHQHSKELCLLAEQLQSLTLFLEAKLEENKAESDI 894
Cdd:pfam02463 328 KELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQE-KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKE 406
|
.
gi 112984402 895 I 895
Cdd:pfam02463 407 A 407
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
423-891 |
5.81e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.42 E-value: 5.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 423 SRHDLEENLLNALvllevlsHQLQAWKSqltVPSRQAQDSSTQTDSSAAVVTKTPKHLQDSKEIRQALLQA--------- 493
Cdd:pfam15921 139 SQEDLRNQLQNTV-------HELEAAKC---LKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEAsgkkiyehd 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 494 -------RNVIHSWGLVSRDL---MSLLHLSLTHVQDDRVTVSQESQ------------RAETLVSSCSRVLKKLRAKLQ 551
Cdd:pfam15921 209 smstmhfRSLGSAISKILRELdteISYLKGRIFPVEDQLEALKSESQnkielllqqhqdRIEQLISEHEVEITGLTEKAS 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 552 SLKTE-----------WEEARHREEMALKGKDAAEAVLEAFRAHASQRISQLEQGItsvQEFRGLLQEAQTQLIGLHTEQ 620
Cdd:pfam15921 289 SARSQansiqsqleiiQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKI---EELEKQLVLANSELTEARTER 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 621 EELAQHTVSLTSALQQDWTSV-----------QQNYGTW--------------------AALLSRSRELTKKLTAKSRQA 669
Cdd:pfam15921 366 DQFSQESGNLDDQLQKLLADLhkrekelslekEQNKRLWdrdtgnsitidhlrrelddrNMEVQRLEALLKAMKSECQGQ 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 670 LQERDAAIEEKDQVVKEVEQVSAHLEDCKGQI---------EQLKLENS-RLTADLSA---------------------- 717
Cdd:pfam15921 446 MERQMAAIQGKNESLEKVSSLTAQLESTKEMLrkvveeltaKKMTLESSeRTVSDLTAslqekeraieatnaeitklrsr 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 718 ---QLQTLASTENELKELQSQHSHC-------------VQDLAMKDELLCQLTQSNKEQAAQWQKE----ETELKHRQAE 777
Cdd:pfam15921 526 vdlKLQELQHLKNEGDHLRNVQTECealklqmaekdkvIEILRQQIENMTQLVGQHGRTAGAMQVEkaqlEKEINDRRLE 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 778 LLQQKAVLAKEVQDLRETmefvdeESQVAHLELGQIE------SQLKATLEVLRERslqcETLKDTVESLRAELASTEAK 851
Cdd:pfam15921 606 LQEFKILKDKKDAKIREL------EARVSDLELEKVKlvnagsERLRAVKDIKQER----DQLLNEVKTSRNELNSLSED 675
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 112984402 852 HEqqALEKTHQHSkelcllAEQLQSLTLFLEAKLEENKAE 891
Cdd:pfam15921 676 YE--VLKRNFRNK------SEEMETTTNKLKMQLKSAQSE 707
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
675-1179 |
5.84e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.66 E-value: 5.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 675 AAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQ-------LQTLASTENELKELQSQHSHCVQDLAMKD 747
Cdd:TIGR00618 170 MNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMpdtyherKQVLEKELKHLREALQQTQQSHAYLTQKR 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 748 ELLCQltQSNKEQAAQWQK---EETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVL 824
Cdd:TIGR00618 250 EAQEE--QLKKQQLLKQLRariEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLL 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 825 RER------SLQCETLKDTVESLRAELASTEAKHEQQALEKTH---QHSKELCLLAEQLQsltlfLEAKLEENKAESDII 895
Cdd:TIGR00618 328 MKRaahvkqQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREIscqQHTLTQHIHTLQQQ-----KTTLTQKLQSLCKEL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 896 LPSTGCAPAQEHPPSSDSSVSEQIPTAVVDEVPEPAPVPLLgsvKSAFTRVASTAPFRPTETPALEKSLAEMSAVLQELQ 975
Cdd:TIGR00618 403 DILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELC---AAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 976 RLCALLQESKEEAVGVL------QREICE-----------------LHTRLQAQEEEHQEAQKAkEADIEKLNQALCLRH 1032
Cdd:TIGR00618 480 QIHLQETRKKAVVLARLlelqeePCPLCGscihpnparqdidnpgpLTRRMQRGEQTYAQLETS-EEDVYHQLTSERKQR 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1033 KNEKELLEVIQkQNEKILGQIDTSGQ-----LINLREEVTQLTRLLRRAETETKVLQEALEGQVDPSCQLMATNWIQEKV 1107
Cdd:TIGR00618 559 ASLKEQMQEIQ-QSFSILTQCDNRSKedipnLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQC 637
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 112984402 1108 FLSQEVNKLRAMFLEVKNEKKQLMDKYLSHRHILEENLRRSDTELKKLddtiQHIYETLLSIPEVVKSCKEL 1179
Cdd:TIGR00618 638 SQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKM----QSEKEQLTYWKEMLAQCQTL 705
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
657-1174 |
6.02e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 47.35 E-value: 6.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 657 ELTKKLTAKSRQALQERDaaieEKDQVVKEVEQVSAHLEDckgQIEQLKLENSrltadlsaQLQTLASTENELKELQSQH 736
Cdd:TIGR00606 416 DLQSKERLKQEQADEIRD----EKKGLGRTIELKKEILEK---KQEELKFVIK--------ELQQLEGSSDRILELDQEL 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 737 SHCVQDLAMKDEllcqltQSNKEQAaqwQKEETELKHRQAELLQQKAVLAKEVQDL------RETMEFVDEESQVAHLEL 810
Cdd:TIGR00606 481 RKAERELSKAEK------NSLTETL---KKEVKSLQNEKADLDRKLRKLDQEMEQLnhhtttRTQMEMLTKDKMDKDEQI 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 811 GQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTE------AKHEQQALEKTHQHSKELCLLAEQLQSLT--LFLE 882
Cdd:TIGR00606 552 RKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRdrlaklNKELASLEQNKNHINNELESKEEQLSSYEdkLFDV 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 883 AKLEENKAESDIILPSTGCAPAQEHPPSSDSSVSEQIPTAVVDEVPEPAPV-----PLLGSVKSAFTRVASTAPFRPTET 957
Cdd:TIGR00606 632 CGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVcqrvfQTEAELQEFISDLQSKLRLAPDKL 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 958 PALEKSLAEMSAVLQELqrlcALLQESKEEAVGVLQREICELHTRLQAQEEEHQEAQ---KAKEADIEKLNQAL-----C 1029
Cdd:TIGR00606 712 KSTESELKKKEKRRDEM----LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKndiEEQETLLGTIMPEEesakvC 787
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1030 LRHKNEKELLEVIQKQNEKILGQIDTSGQLINLREEVTQLTRllRRAETETKVLQEALEGQVDPSCqlmatnwIQEKvfl 1109
Cdd:TIGR00606 788 LTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQ--EKQEKQHELDTVVSKIELNRKL-------IQDQ--- 855
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 1110 SQEVNKLRAMFLEVKNEKKQLMDKyLSHRHILEENLRRSDTELKKLDDTIQHIYETLLSIPEVVK 1174
Cdd:TIGR00606 856 QEQIQHLKSKTNELKSEKLQIGTN-LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE 919
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
536-1082 |
7.28e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 47.27 E-value: 7.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 536 VSSCSRVLKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAVLEAFRAHASQRIsQLEQGITSVQEFRGLLQEAQTQLIG 615
Cdd:TIGR00618 302 VTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEI-HIRDAHEVATSIREISCQQHTLTQH 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 616 LHTEQEELaQHTVSLTSALQQDWTSVQQNYGTWAALLSRSRELT-KKLTAKSRQALQERDAAIEE-------KDQVVKEV 687
Cdd:TIGR00618 381 IHTLQQQK-TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQgQLAHAKKQQELQQRYAELCAaaitctaQCEKLEKI 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 688 EQVSA-----HLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKElQSQHSHCVQDLAMKDELLCQLTQSNKEQAA 762
Cdd:TIGR00618 460 HLQESaqslkEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCG-SCIHPNPARQDIDNPGPLTRRMQRGEQTYA 538
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 763 QWQKEETELKHRQAELLQQKAVLAKEVQDLRETMefvdeesqvahLELGQIESQLKATLEVLRErsLQCETLKDTVESLR 842
Cdd:TIGR00618 539 QLETSEEDVYHQLTSERKQRASLKEQMQEIQQSF-----------SILTQCDNRSKEDIPNLQN--ITVRLQDLTEKLSE 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 843 AELASTEAKHEQQALEKTHQHSKELCLLAEQLQSLtlflEAKLEENKAESDIILPSTgcapAQEHPPSSDSSVSEQIPTA 922
Cdd:TIGR00618 606 AEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE----LALKLTALHALQLTLTQE----RVREHALSIRVLPKELLAS 677
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 923 VVDEVPEpapvplLGSVKSAFTRVASTAPFRPTETPALEKSLAEMSAVLQELQRLCALLQ---ESKEEAVGVLQREICEL 999
Cdd:TIGR00618 678 RQLALQK------MQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGsdlAAREDALNQSLKELMHQ 751
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1000 H-TRLQAQEEEHQEAQKAKEADIEKLNQ--ALCLRHKNEKELLEVIQKQNEKILGQIDTSGQLINLREEVTQLTRLLRRA 1076
Cdd:TIGR00618 752 ArTVLKARTEAHFNNNEEVTAALQTGAElsHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEE 831
|
....*.
gi 112984402 1077 ETETKV 1082
Cdd:TIGR00618 832 QFLSRL 837
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
570-771 |
7.59e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 7.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 570 GKDAAEAvLEAFRahasQRISQLEQGITSVQEFRGLLQEAQTQLIGLHTEQEELAQHtvsltSALQQDWTSVQQNYGTW- 648
Cdd:COG4913 605 GFDNRAK-LAALE----AELAELEEELAEAEERLEALEAELDALQERREALQRLAEY-----SWDEIDVASAEREIAELe 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 649 ---AALLSRSRELtKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLAst 725
Cdd:COG4913 675 aelERLDASSDDL-AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL-- 751
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 112984402 726 ENELKELQSQHSHcvqdlamkDELLCQLTQSNKEQAAQWQKEETEL 771
Cdd:COG4913 752 EERFAAALGDAVE--------RELRENLEERIDALRARLNRAEEEL 789
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
809-1049 |
9.50e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 9.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 809 ELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKheqqaLEKTHQHSKELCLLAEQLQSLTLFLEAKLEEN 888
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-----IRALEQELAALEAELAELEKEIAELRAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 889 KAEsdiilpstgcapaqehppssdssVSEQIPTAVVDEvpEPAPVPLLGSVKSAFTRVASTAPFRpTETPALEKSLAEMS 968
Cdd:COG4942 103 KEE-----------------------LAELLRALYRLG--RQPPLALLLSPEDFLDAVRRLQYLK-YLAPARREQAEELR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 969 AVLQELQRLCALLQESKEEAVgVLQREICELHTRLQAQEEEHQEAQKAKEADIEKLNQALCLRHKNEKELLEVIQKQNEK 1048
Cdd:COG4942 157 ADLAELAALRAELEAERAELE-ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
.
gi 112984402 1049 I 1049
Cdd:COG4942 236 A 236
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
713-867 |
9.76e-05 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 44.54 E-value: 9.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 713 ADLSAQLQtlASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDL 792
Cdd:pfam08614 13 LDRTALLE--AENAKLQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQEL 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 793 RETMEFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKheqqaLEKTHQHSKEL 867
Cdd:pfam08614 91 EKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEK-----LRKLEKENREL 160
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
526-893 |
2.08e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.90 E-value: 2.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 526 SQESQRAETLVSSCSRVLK--KLRAKLQSLKTEWEEARHREEMALKGKDAAEAVlEAFRAHASQRISQLEQGitsvQEFR 603
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKadEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE-EAKKADEAKKAEEAKKA----DEAK 1540
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 604 GLLQEAQTQLIglhTEQEELAQhtvsltsalQQDWTSVQQNygtwaallSRSRELTKKLTAKSRQALQERDAAIEEKDQV 683
Cdd:PTZ00121 1541 KAEEKKKADEL---KKAEELKK---------AEEKKKAEEA--------KKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 684 VKEVEQVSAHlEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQ 763
Cdd:PTZ00121 1601 YEEEKKMKAE-EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE 1679
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 764 WQKEETElKHRQAELLQQKAVLAKEVQDLRETMEfvdEESQVAHlelgqiesQLKATLEvlrERSLQCETLKDTVESLRA 843
Cdd:PTZ00121 1680 AKKAEED-EKKAAEALKKEAEEAKKAEELKKKEA---EEKKKAE--------ELKKAEE---ENKIKAEEAKKEAEEDKK 1744
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 112984402 844 ElaSTEAKHEQQALEKTHQHSKELCLLAEQLQSLTlflEAKLEENKAESD 893
Cdd:PTZ00121 1745 K--AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEK---EAVIEEELDEED 1789
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
588-1076 |
2.16e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.44 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 588 RISQLEQGITSV----QEFRGLLQEAQTQLIGLHTEQEELAQHTVSLTSaLQQDWTSVQQNYGTWAALLSRSRELTKKLT 663
Cdd:PRK03918 194 LIKEKEKELEEVlreiNEISSELPELREELEKLEKEVKELEELKEEIEE-LEKELESLEGSKRKLEEKIRELEERIEELK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 664 AKSRQaLQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSA---QLQTLASTENELKELQSQHSHCV 740
Cdd:PRK03918 273 KEIEE-LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGieeRIKELEEKEERLEELKKKLKELE 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 741 QDLAM--KDELLCQLTQSNKEQAAQWQKEET-------------------ELKHRQAELLQQKAVLAKEVQDLRETME-- 797
Cdd:PRK03918 352 KRLEEleERHELYEEAKAKKEELERLKKRLTgltpeklekeleelekakeEIEEEISKITARIGELKKEIKELKKAIEel 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 798 ------------FVDEESQVA-----HLELGQIESQLKATLEVLRE----------------RSLQCETLKDTVESLRAE 844
Cdd:PRK03918 432 kkakgkcpvcgrELTEEHRKElleeyTAELKRIEKELKEIEEKERKlrkelrelekvlkkesELIKLKELAEQLKELEEK 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 845 LAS---TEAKHEQQALEKTHQHS----KELCLLAEQLQSLTLF------LEAKL---EENKAESDIILPSTGCapaqehp 908
Cdd:PRK03918 512 LKKynlEELEKKAEEYEKLKEKLiklkGEIKSLKKELEKLEELkkklaeLEKKLdelEEELAELLKELEELGF------- 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 909 pSSDSSVSEQIptavvdEVPEPAPVPLLgSVKSAFTRVASTAPFRPTETPALEKSLAEMSAVLQELQRLCALLQE----- 983
Cdd:PRK03918 585 -ESVEELEERL------KELEPFYNEYL-ELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEElekky 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 984 SKEEAVGVLQR--EICELHTRLQAQEEEHQEAQKAKEADIEKLNQALCLRHKNEKElLEVIQKQNEKilgqidtsgqLIN 1061
Cdd:PRK03918 657 SEEEYEELREEylELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE-LEKLEKALER----------VEE 725
|
570
....*....|....*
gi 112984402 1062 LREEVTQLTRLLRRA 1076
Cdd:PRK03918 726 LREKVKKYKALLKER 740
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
959-1186 |
3.51e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 3.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 959 ALEKSLAEMSAVLQELQRLCALLQESKEEAVGVLQRE-ICELHTRLQAQEEEHQEAqkakEADIEKLNQALCLRHKnEKE 1037
Cdd:TIGR02169 755 NVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSrIPEIQAELSKLEEEVSRI----EARLREIEQKLNRLTL-EKE 829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1038 LLEviQKQNEKILGQIDTSGQLINLREEVTQLTRLLRRAETETKVLQEALEgqvdpscQLmatnwIQEKVFLSQEVNKLR 1117
Cdd:TIGR02169 830 YLE--KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR-------DL-----ESRLGDLKKERDELE 895
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 1118 AMFLEVKNEKKQLMDKYLSHRHILE------ENLRRSDTELKKLDDTIQHIYETLLSIPEVVKSCKELQGLLEFL 1186
Cdd:TIGR02169 896 AQLRELERKIEELEAQIEKKRKRLSelkaklEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
651-1180 |
3.71e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 44.67 E-value: 3.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 651 LLSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLklensrltadlSAQLQTLASTENELK 730
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKL-----------EKEVKELEELKEEIE 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 731 ELQSQHSHCVQDLAMKDELLCQLTQSNKEQaaqwQKEETELKHRQAELLQQKAVlAKEVQDLRETMEFVDEESQVAHLEL 810
Cdd:PRK03918 242 ELEKELESLEGSKRKLEEKIRELEERIEEL----KKEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 811 GQIESQLKATLEVLRERS---LQCETLKDTVESLRAELASTEAKHE-----QQALEKTHQHSKEL-CLLAEQLQSLTLFL 881
Cdd:PRK03918 317 SRLEEEINGIEERIKELEekeERLEELKKKLKELEKRLEELEERHElyeeaKAKKEELERLKKRLtGLTPEKLEKELEEL 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 882 EAKLEENKAESDIILPSTGcapaqehppsSDSSVSEQIPTAVVDEVPEPAPVPLLGsvksaftrvastapfRPT----ET 957
Cdd:PRK03918 397 EKAKEEIEEEISKITARIG----------ELKKEIKELKKAIEELKKAKGKCPVCG---------------RELteehRK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 958 PALEKSLAEMSAVLQELQRLCALLQESKEEAVGV-----LQREICELHTRLQaQEEEHQEaqKAKEADIEKLNQALCLRH 1032
Cdd:PRK03918 452 ELLEEYTAELKRIEKELKEIEEKERKLRKELRELekvlkKESELIKLKELAE-QLKELEE--KLKKYNLEELEKKAEEYE 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1033 KNEKELLEViqkqnekilgqidtSGQLINLREEVTQLTRLLRRAETETKVLQEALEGQVDPSCQLmatnwiQEKVFLSQE 1112
Cdd:PRK03918 529 KLKEKLIKL--------------KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL------EELGFESVE 588
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 112984402 1113 VNKLRAMFLEvknekkQLMDKYLS---HRHILEENLRRSDTELKKLDDTIQHIYETLLSIPEVVKSCKELQ 1180
Cdd:PRK03918 589 ELEERLKELE------PFYNEYLElkdAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELE 653
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
582-828 |
4.45e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 44.66 E-value: 4.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 582 RAHASQRISQLEQGItsvQEFRGLLQEAQTQLIglhTEQEELAQHTVSLTS-ALQQDwtsvqqnygtwaaLLSRSRELTK 660
Cdd:PRK10929 60 RKGSLERAKQYQQVI---DNFPKLSAELRQQLN---NERDEPRSVPPNMSTdALEQE-------------ILQVSSQLLE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 661 KltakSRQALQERDAAIEekdqvvkeveqvsahLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQ--SQHSH 738
Cdd:PRK10929 121 K----SRQAQQEQDRARE---------------ISDSLSQLPQQQTEARRQLNEIERRLQTLGTPNTPLAQAQltALQAE 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 739 CVQDLAMKDEL-LCQLTQSNKEqaaqwqkeetELKHRQAELLQQKAV-LAKEVQDLRETMEFV---DEESQVAHLEL--- 810
Cdd:PRK10929 182 SAALKALVDELeLAQLSANNRQ----------ELARLRSELAKKRSQqLDAYLQALRNQLNSQrqrEAERALESTELlae 251
|
250 260
....*....|....*....|
gi 112984402 811 --GQIESQLKATLEVLRERS 828
Cdd:PRK10929 252 qsGDLPKSIVAQFKINRELS 271
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
526-797 |
4.79e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 4.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 526 SQESQRAETLVSSCSRV--LKKLRAKLQSLKTEWEEARhREEMALKGKDAAEAvlEAFRAHASQRISQLEQGITSVQEFR 603
Cdd:COG3096 857 AQEQQLRQQLDQLKEQLqlLNKLLPQANLLADETLADR-LEELREELDAAQEA--QAFIQQHGKALAQLEPLVAVLQSDP 933
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 604 GLLQEAQTQLIGLHTEQEELAQHTVSLTSALQQdwtSVQQNYGTWAALLSRSRELTKKLTAKSRQALQERDAAIEEKDQV 683
Cdd:COG3096 934 EQFEQLQADYLQAKEQQRRLKQQIFALSEVVQR---RPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQA 1010
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 684 VKEVEQVSAHLEDCKGQieqlklensrltadLSAQLQTLASTENELKELQSQHSHCVQDLAM--KDELLCQLTQSnkeqA 761
Cdd:COG3096 1011 QAQYSQYNQVLASLKSS--------------RDAKQQTLQELEQELEELGVQADAEAEERARirRDELHEELSQN----R 1072
|
250 260 270
....*....|....*....|....*....|....*....
gi 112984402 762 AQWQKEETELKHRQAEL--LQQKAVLA-KEVQDLRETME 797
Cdd:COG3096 1073 SRRSQLEKQLTRCEAEMdsLQKRLRKAeRDYKQEREQVV 1111
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
549-896 |
5.09e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.75 E-value: 5.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 549 KLQSLKTEWEEARHREEMALKGKDAAEAVLEAFRAHASQRISQL----EQGITSVQEFRGLLQEAQTQLIGLHTEQEELA 624
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAkkkaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA 1524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 625 QHTVSLTSALQQDWTSVQQNYGTwAALLSRSRELTKkltAKSRQALQERDAAIEEKDQVVKEVEQVSahledckgQIEQL 704
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKK-ADELKKAEELKK---AEEKKKAEEAKKAEEDKNMALRKAEEAK--------KAEEA 1592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 705 KLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAV 784
Cdd:PTZ00121 1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEE 1672
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 785 LAKEVQDLREtmefvDEESQVAHLELGQIESQLKATLEVLR----ERSLQCETLK--DTVESLRAELASTEAKHEQQALE 858
Cdd:PTZ00121 1673 DKKKAEEAKK-----AEEDEKKAAEALKKEAEEAKKAEELKkkeaEEKKKAEELKkaEEENKIKAEEAKKEAEEDKKKAE 1747
|
330 340 350
....*....|....*....|....*....|....*...
gi 112984402 859 KTHQHSKElcllAEQLQSLTLFLEAKLEENKAESDIIL 896
Cdd:PTZ00121 1748 EAKKDEEE----KKKIAHLKKEEEKKAEEIRKEKEAVI 1781
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
652-1094 |
5.86e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.26 E-value: 5.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 652 LSRSRELTKKLTAKSRQALQERDAA---IEEKDQVVKEVEQVSAHLEDCKGQIEqlklENSRLTADLSAQLQTLastENE 728
Cdd:PRK02224 215 LAELDEEIERYEEQREQARETRDEAdevLEEHEERREELETLEAEIEDLRETIA----ETEREREELAEEVRDL---RER 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 729 LKELQSQHSHCVQDLAMKDelLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAvlAKEVQDLRETMEFVDEESQVAHL 808
Cdd:PRK02224 288 LEELEEERDDLLAEAGLDD--ADAEAVEARREELEDRDEELRDRLEECRVAAQAH--NEEAESLREDADDLEERAEELRE 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 809 ELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAkheqqALEKTHQHSKELCLLAEQLQSLTLFLEAKL--- 885
Cdd:PRK02224 364 EAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV-----DLGNAEDFLEELREERDELREREAELEATLrta 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 886 EENKAESDIILPSTGCapaqehpPSSDSSVSEQIPTAVVDEVPEPAP--VPLLGSVKSAFTRVAStapfRPTETPALEKS 963
Cdd:PRK02224 439 RERVEEAEALLEAGKC-------PECGQPVEGSPHVETIEEDRERVEelEAELEDLEEEVEEVEE----RLERAEDLVEA 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 964 LAEMSAVLQELQRLCALLQ------ESKEEAVGVLQREICELHTRLQAQEEE----HQEAQKAKEAdIEKLNQALClRHK 1033
Cdd:PRK02224 508 EDRIERLEERREDLEELIAerretiEEKRERAEELRERAAELEAEAEEKREAaaeaEEEAEEAREE-VAELNSKLA-ELK 585
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 112984402 1034 NEKELLEVIQKQNEKILGQIDTSGQLINLREEVTQLTRLLRRAETETKVLQEALEGQVDPS 1094
Cdd:PRK02224 586 ERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA 646
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
946-1162 |
5.94e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 5.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 946 VASTAPFRPTETPALEKSLAEMSAVLQELQRLCALLQESKEEAVGVLQ---REICELHTRLQAQEEEHQEAQK---AKEA 1019
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAaleRRIAALARRIRALEQELAALEAelaELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1020 DIEKLNQALCLRHKNEKELLEVIQKQNE----KILGQIDTSGQLINLREEVTQLTRLLRRAETETKVLQEALEGQvdpsc 1095
Cdd:COG4942 91 EIAELRAELEAQKEELAELLRALYRLGRqpplALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAAL----- 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 112984402 1096 QLMATNWIQEKVFLSQEVNKLRAMFLEVKNEKKQLMDKYLSHRHILEENLRRSDTELKKLDDTIQHI 1162
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
541-1079 |
8.77e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 8.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 541 RVLKKLRAKLQSLKTEWEEArhreemalkgkDAAEAVLEAFRA-HASQRISQLEQGItsvQEFRGLLQEAQTQLIGLHTE 619
Cdd:COG4913 252 ELLEPIRELAERYAAARERL-----------AELEYLRAALRLwFAQRRLELLEAEL---EELRAELARLEAELERLEAR 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 620 QEELAQHTVSLTSALQQdwtsvqQNYGTWAALLSRSRELTKKLTAKSRQALQERDAAI-------EEKDQVVKEVEQVSA 692
Cdd:COG4913 318 LDALREELDELEAQIRG------NGGDRLEQLEREIERLERELEERERRRARLEALLAalglplpASAEEFAALRAEAAA 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 693 HLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSHCVQDL-AMKDELlcqltqsnkeqAAQWQKEETEL 771
Cdd:COG4913 392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLlALRDAL-----------AEALGLDEAEL 460
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 772 KHrQAELLQ--------QKAV----------LAKEVQDLRETMEFVDEESQVAHLELGQIESQL-KATLEVLRERSLQCE 832
Cdd:COG4913 461 PF-VGELIEvrpeeerwRGAIervlggfaltLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLpDPERPRLDPDSLAGK 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 833 -TLKDTV--ESLRAELA---------STEA-KHEQQALEKT---------HQH-----------------------SKEL 867
Cdd:COG4913 540 lDFKPHPfrAWLEAELGrrfdyvcvdSPEElRRHPRAITRAgqvkgngtrHEKddrrrirsryvlgfdnraklaalEAEL 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 868 CLLAEQLQSLtlflEAKLEENKAESDiilpstgcapaqehppssdssvseqiptavvdevpepapvpLLGSVKSAFTRVA 947
Cdd:COG4913 620 AELEEELAEA----EERLEALEAELD-----------------------------------------ALQERREALQRLA 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 948 STApFRPTETPALEKSLAEM----------SAVLQELQRLCALLQESKEEA---VGVLQREICELHTRLQAQEEEHQEAQ 1014
Cdd:COG4913 655 EYS-WDEIDVASAEREIAELeaelerldasSDDLAALEEQLEELEAELEELeeeLDELKGEIGRLEKELEQAEEELDELQ 733
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 112984402 1015 KAKEA--DIEKLNQALCLrhknEKELLEVIQKQNEKILGQidtsgqliNLREEVTQLTRLLRRAETE 1079
Cdd:COG4913 734 DRLEAaeDLARLELRALL----EERFAAALGDAVERELRE--------NLEERIDALRARLNRAEEE 788
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
654-881 |
9.64e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.35 E-value: 9.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 654 RSRELTKKLTAKSRQALQERDAAIEEKdqvVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTL----ASTENEL 729
Cdd:pfam07888 55 RQREKEKERYKRDREQWERQRRELESR---VAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALlaqrAAHEARI 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 730 KELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKA---VLAKEVQDLRETMEFVDEESQVA 806
Cdd:pfam07888 132 RELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEelrSLSKEFQELRNSLAQRDTQVLQL 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 807 HLELGQI----------ESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALEkTHQHSKELCLLAEQLQS 876
Cdd:pfam07888 212 QDTITTLtqklttahrkEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAE-LHQARLQAAQLTLQLAD 290
|
....*
gi 112984402 877 LTLFL 881
Cdd:pfam07888 291 ASLAL 295
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
558-856 |
9.67e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.67 E-value: 9.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 558 EEARHREEMALKGKDAAEAVLEAFRAHASQRISQLEQGITSVQEFRGLLQEAQTQLIG--------LHTEQEELAQHTVS 629
Cdd:pfam12128 474 ERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPqagtllhfLRKEAPDWEQSIGK 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 630 LTSALQ--------QDWTSVQQNYGTWAALLSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEV-EQVSAHLEDCKGQ 700
Cdd:pfam12128 554 VISPELlhrtdldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKqAAAEEQLVQANGE 633
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 701 IEQLKLENSRltadlsaQLQTLASTENELKELQSQHshcvQDLAMKdellcqLTQSNKEQAAQWQKEETELKHRQAELL- 779
Cdd:pfam12128 634 LEKASREETF-------ARTALKNARLDLRRLFDEK----QSEKDK------KNKALAERKDSANERLNSLEAQLKQLDk 696
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 780 QQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRE----RSLQCET-----LK------DTVESLRAE 844
Cdd:pfam12128 697 KHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSgakaELKALETwykrdLAslgvdpDVIAKLKRE 776
|
330
....*....|..
gi 112984402 845 LASTEAKHEQQA 856
Cdd:pfam12128 777 IRTLERKIERIA 788
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
587-764 |
1.11e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.22 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 587 QRISQLEQGITSVQEFRGLLQEAQTQLIGLHTEQEELAQHTVSLTSALQQ--DWTSVQQNYGTWAALLSRSRELTKKLtA 664
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleKLLQLLPLYQELEALEAELAELPERL-E 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 665 KSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLEN-SRLTADLSAQLQTLASTENELKELQSQHSHCVQDL 743
Cdd:COG4717 150 ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229
|
170 180
....*....|....*....|.
gi 112984402 744 AMKDELLCQLTQSNKEQAAQW 764
Cdd:COG4717 230 EQLENELEAAALEERLKEARL 250
|
|
| ATG14 |
pfam10186 |
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are ... |
603-803 |
1.11e-03 |
|
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are hydrophilic proteins with a predicted molecular mass of 40.5 kDa, and have a coiled-coil motif at the N terminus region. Yeast cells with mutant Atg14 are defective not only in autophagy but also in sorting of carboxypeptidase Y (CPY), a vacuolar-soluble hydrolase, to the vacuole. Subcellular fractionation indicate that Apg14p and Apg6p are peripherally associated with a membrane structure(s). Apg14p was co-immunoprecipitated with Apg6p, suggesting that they form a stable protein complex. These results imply that Apg6/Vps30p has two distinct functions: in the autophagic process and in the vacuolar protein sorting pathway. Apg14p may be a component specifically required for the function of Apg6/Vps30p through the autophagic pathway. There are 17 auto-phagosomal component proteins which are categorized into six functional units, one of which is the AS-PI3K complex (Vps30/Atg6 and Atg14). The AS-PI3K complex and the Atg2-Atg18 complex are essential for nucleation, and the specific function of the AS-PI3K apparently is to produce phosphatidylinositol 3-phosphate (PtdIns(3)P) at the pre-autophagosomal structure (PAS). The localization of this complex at the PAS is controlled by Atg14. Autophagy mediates the cellular response to nutrient deprivation, protein aggregation, and pathogen invasion in humans, and malfunction of autophagy has been implicated in multiple human diseases including cancer. This effect seems to be mediated through direct interaction of the human Atg14 with Beclin 1 in the human phosphatidylinositol 3-kinase class III complex.
Pssm-ID: 462986 [Multi-domain] Cd Length: 347 Bit Score: 42.83 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 603 RGLLQEAQTQLIGLHTEQEELAQHtvsLTSALQqdwtsvqqnyGTWAALLSRSRELTKKLTAKSRQALQerdAAIEEKDQ 682
Cdd:pfam10186 18 RNRLYELRVDLARLLSEKDSLKKK---VEEALE----------GKEEGEQLEDNIGNKKLKLRLLKSEV---AISNERLN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 683 VVKE-VEQVSAHLEDCKGQIEQLKLENSRLTADLSaqlqtlaSTENELKELQSqhshcvqdlamkdELLCQLTQSNKEQA 761
Cdd:pfam10186 82 EIKDkLDQLRREIAEKKKKIEKLRSSLKQRRSDLE-------SASYQLEERRA-------------SQLAKLQNSIKRIK 141
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 112984402 762 AQWQKEETELKHRQAELLQQKAVLAkevqDLRETMEFVDEES 803
Cdd:pfam10186 142 QKWTALHSKTAESRSFLCRELAKLY----GLRQVVKSKNGSS 179
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
507-1162 |
2.00e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.52 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 507 LMSLLHLSLTHVQDDRVTVSQESQRAETLvsscsrvlKKLRAKLQSLKTEWEEARHREEMALKgkdAAEAVLEAFRAHAS 586
Cdd:pfam12128 257 ELRLSHLHFGYKSDETLIASRQEERQETS--------AELNQLLRTLDDQWKEKRDELNGELS---AADAAVAKDRSELE 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 587 QRISQLEQGITSVQEFRGLLQEaqtQLIGLHTEQEELAQHTVSLTSALQqdwtSVQQNYGTWAALlsRSRELTKKLtaks 666
Cdd:pfam12128 326 ALEDQHGAFLDADIETAAADQE---QLPSWQSELENLEERLKALTGKHQ----DVTAKYNRRRSK--IKEQNNRDI---- 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 667 rQALQERDAAIeeKDQVVKEVEQVSAHLEdckGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQ---HSHCVQDL 743
Cdd:pfam12128 393 -AGIKDKLAKI--REARDRQLAVAEDDLQ---ALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQataTPELLLQL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 744 AMKDELL----CQLTQSNKEQ--------AAQWQKEETELKHRQAE--LLQQK------------------AVLAKEVQD 791
Cdd:pfam12128 467 ENFDERIerarEEQEAANAEVerlqselrQARKRRDQASEALRQASrrLEERQsaldelelqlfpqagtllHFLRKEAPD 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 792 LRETM---------------EFVDEESQVAHLELGQIESQLKAtlevlrersLQCETLKDTVESLRAELASTEaKHEQQA 856
Cdd:pfam12128 547 WEQSIgkvispellhrtdldPEVWDGSVGGELNLYGVKLDLKR---------IDVPEWAASEEELRERLDKAE-EALQSA 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 857 LEKTHQHSKELCLLAEQLQSLTLFLE-AKLEENKAESDIILPSTgcapaqEHPPSSDsSVSEQIPTAvvdevpepapvpl 935
Cdd:pfam12128 617 REKQAAAEEQLVQANGELEKASREETfARTALKNARLDLRRLFD------EKQSEKD-KKNKALAER------------- 676
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 936 lgsVKSAFTRVASTApfrptetpalekslAEMSAVLQELQrlcALLQESKEEAVgvlqreicELHTRLQAQEEEHQEAQK 1015
Cdd:pfam12128 677 ---KDSANERLNSLE--------------AQLKQLDKKHQ---AWLEEQKEQKR--------EARTEKQAYWQVVEGALD 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1016 AKEAdieKLNQALCLRHKNEKELLEVIQKQNEKILGQIDTSGQ-LINLREEVTQLTRLLRRAEtetKVLQEALEGQvdps 1094
Cdd:pfam12128 729 AQLA---LLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDvIAKLKREIRTLERKIERIA---VRRQEVLRYF---- 798
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 112984402 1095 cQLMATNWIQEKVFLSQEVNKLRAMFLEVKNEKKQLMD-------KYLSHRHILEENLRRSDTELKKLDDTIQHI 1162
Cdd:pfam12128 799 -DWYQETWLQRRPRLATQLSNIERAISELQQQLARLIAdtklrraKLEMERKASEKQQVRLSENLRGLRCEMSKL 872
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
670-848 |
2.29e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.06 E-value: 2.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 670 LQERDAAIeekDQVVKEVEQVSAHLEDCKGQIEQLKlensrltADLSAQLQTLASTENELKELQSQHSHCVQDLAmKDEL 749
Cdd:COG1579 12 LQELDSEL---DRLEHRLKELPAELAELEDELAALE-------ARLEAAKTELEDLEKEIKRLELEIEEVEARIK-KYEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 750 LCQLTQSNKEQAAQwQKEETELKHRQAELlqqkavlAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRERSL 829
Cdd:COG1579 81 QLGNVRNNKEYEAL-QKEIESLKRRISDL-------EDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELA 152
|
170
....*....|....*....
gi 112984402 830 QCETLKDTVESLRAELAST 848
Cdd:COG1579 153 ELEAELEELEAEREELAAK 171
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
478-715 |
2.63e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 2.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 478 KHLQDSKEIRQALLQARNVIHSWGLVSRDLMSLLHLSLTHVQDDRVTVSQESQRAETLVSSCSRVLKKLRAKLQSLKTEW 557
Cdd:COG4913 232 EHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAEL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 558 EEARHREEMAlkgKDAAEAVLEAFRAHASQRISQLEQGITSvqefrglLQEAQTQLIGLHTEQEELAQhTVSLTSALQQD 637
Cdd:COG4913 312 ERLEARLDAL---REELDELEAQIRGNGGDRLEQLEREIER-------LERELEERERRRARLEALLA-ALGLPLPASAE 380
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 112984402 638 wtsvqqnygTWAALLSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEQVSAhledckgQIEQLKLENSRLTADL 715
Cdd:COG4913 381 ---------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA-------EIASLERRKSNIPARL 442
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
710-1146 |
3.05e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.03 E-value: 3.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 710 RLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEV 789
Cdd:pfam15921 78 RVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 790 QDLRETMeFVDEESQVahlelgqiesqlkatlEVLRERSLQCETLKDTVESLRA--ELASTEAKHEQQALEKTHQHS--- 864
Cdd:pfam15921 158 KCLKEDM-LEDSNTQI----------------EQLRKMMLSHEGVLQEIRSILVdfEEASGKKIYEHDSMSTMHFRSlgs 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 865 ------KELCLLAEQLQSLTLFLEAKLEENKAES----DIILpstgcapaQEHPPSSDSSVSE-QIPTAVVDEVPEPAPV 933
Cdd:pfam15921 221 aiskilRELDTEISYLKGRIFPVEDQLEALKSESqnkiELLL--------QQHQDRIEQLISEhEVEITGLTEKASSARS 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 934 PLlGSVKSAFTRVASTAPFRPT----ETPALEKSLAEMSAVLQELQRLcallqesKEEAVGVLQREICELHTRL-QAQEE 1008
Cdd:pfam15921 293 QA-NSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRM-------YEDKIEELEKQLVLANSELtEARTE 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1009 EHQEAQKAKEADiEKLNQALCLRHKNEKELleVIQKQNEKILGQIDTSGQLI--NLREEVTQLTRLLRRAETETKVLQEA 1086
Cdd:pfam15921 365 RDQFSQESGNLD-DQLQKLLADLHKREKEL--SLEKEQNKRLWDRDTGNSITidHLRRELDDRNMEVQRLEALLKAMKSE 441
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1087 LEGQVDpscQLMATnwIQEKVFLSQEVNKLRAMFLEVKNEKKQLMDKYLSHRHILEENLR 1146
Cdd:pfam15921 442 CQGQME---RQMAA--IQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSER 496
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
657-837 |
3.08e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.54 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 657 ELTKKLTAKSRQALQERDAAIeekDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQH 736
Cdd:PHA02562 202 KNIEEQRKKNGENIARKQNKY---DELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVI 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 737 SH---------CVQDLAMKDELLCQLTQSNKEQAAQWQKEET---ELKHRQAELLQQKAVL------------------- 785
Cdd:PHA02562 279 KMyekggvcptCTQQISEGPDRITKIKDKLKELQHSLEKLDTaidELEEIMDEFNEQSKKLlelknkistnkqslitlvd 358
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 112984402 786 -AKEVQDL--RETMEFVDEESQVAHL--ELGQIESQLKATLEVLRERSLQCETLKDT 837
Cdd:PHA02562 359 kAKKVKAAieELQAEFVDNAEELAKLqdELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
|
|
| PRK10246 |
PRK10246 |
exonuclease subunit SbcC; Provisional |
573-1029 |
4.06e-03 |
|
exonuclease subunit SbcC; Provisional
Pssm-ID: 182330 [Multi-domain] Cd Length: 1047 Bit Score: 41.32 E-value: 4.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 573 AAEAVLEAFRAHASQRI----SQLEQGITSVQefrGLLQEAQTQLIGLHTEQEELaqHTVSLTSALQQDWTSVQQN-YGT 647
Cdd:PRK10246 195 SARTELEKLQAQASGVAlltpEQVQSLTASLQ---VLTDEEKQLLTAQQQQQQSL--NWLTRLDELQQEASRRQQAlQQA 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 648 WAALLSRSRELTKKLTAKSRQAL-------QERDAAIEekdQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQ 720
Cdd:PRK10246 270 LAAEEKAQPQLAALSLAQPARQLrphweriQEQSAALA---HTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQ 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 721 TLAS--TENELKELQSqhshcvQDLAMKDELLCQLTqSNKEQAAQWQKEETELKHRQAELlqQKAVLAKEVQDLRETMef 798
Cdd:PRK10246 347 SLNTwlAEHDRFRQWN------NELAGWRAQFSQQT-SDREQLRQWQQQLTHAEQKLNAL--PAITLTLTADEVAAAL-- 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 799 vdeESQVAHLELGQIESQLKATLEVLRERSLQcetLKDTVESLRAELASTEAKHEQ--QALEKTHQHSKELCLLAEQLQS 876
Cdd:PRK10246 416 ---AQHAEQRPLRQRLVALHGQIVPQQKRLAQ---LQVAIQNVTQEQTQRNAALNEmrQRYKEKTQQLADVKTICEQEAR 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 877 LtlfleAKLEENKAESDIILPSTGCA----PAQEHPPSSDSSVSEQIPTAVVDEVPEPAP--VPLLGSVKsAFTRVasta 950
Cdd:PRK10246 490 I-----KDLEAQRAQLQAGQPCPLCGstshPAVEAYQALEPGVNQSRLDALEKEVKKLGEegAALRGQLD-ALTKQ---- 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 951 pfRPTETPALEKSLAEMSAVLQELQRLCALL---QESKEEAVGVLQ------REICELHTR--LQAQEEEHQEAQKAKEA 1019
Cdd:PRK10246 560 --LQRDESEAQSLRQEEQALTQQWQAVCASLnitLQPQDDIQPWLDaqeeheRQLRLLSQRheLQGQIAAHNQQIIQYQQ 637
|
490
....*....|
gi 112984402 1020 DIEKLNQALC 1029
Cdd:PRK10246 638 QIEQRQQQLL 647
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
651-1143 |
4.31e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.25 E-value: 4.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 651 LLSRSRELTKKLTAKSRQALQERDAAIEEKDQVVKEVEqvsahledckgqieqlklensrltaDLSAQLQTLASTENELK 730
Cdd:pfam05483 262 LLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELE-------------------------DIKMSLQRSMSTQKALE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 731 ElqsqhshcvqDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAHLEL 810
Cdd:pfam05483 317 E----------DLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMEL 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 811 GQIESQLKATLEVLRERSLQCETLKDTVeslraelasteaKHEQQALEKTHQHSKelclLAEQL----QSLTLFLEAKle 886
Cdd:pfam05483 387 QKKSSELEEMTKFKNNKEVELEELKKIL------------AEDEKLLDEKKQFEK----IAEELkgkeQELIFLLQAR-- 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 887 eNKAESDIILPSTGCAPAQEHppssdssvseqiptavvdevpepapvpLLGSVKSAFTRVASTAPFRPTETPALEKSLAE 966
Cdd:pfam05483 449 -EKEIHDLEIQLTAIKTSEEH---------------------------YLKEVEDLKTELEKEKLKNIELTAHCDKLLLE 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 967 MSAVLQELQRLCALLQESKEEAVGVLQREICELHTRLQAQEEEHQ---EAQKAKEADIEKLNQALCLRHKNEKELLEVIQ 1043
Cdd:pfam05483 501 NKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNlrdELESVREEFIQKGDEVKCKLDKSEENARSIEY 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1044 KQNEKILGQIDTSGQLINLREEVTQLTRLLRRAETETKVLQEALEGQvdpSCQLMATNWIQEKVFLSQEVNKLRamFLEV 1123
Cdd:pfam05483 581 EVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAE---NKQLNAYEIKVNKLELELASAKQK--FEEI 655
|
490 500
....*....|....*....|.
gi 112984402 1124 KNE-KKQLMDKYLSHRHILEE 1143
Cdd:pfam05483 656 IDNyQKEIEDKKISEEKLLEE 676
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
580-891 |
4.33e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 4.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 580 AFRAHASQRISQLEQGITSVQEF---RGLLQEAQTQLIGLHTEQEELaqhtVSLTSALQQDWTSVQQnygtWAALLSRSR 656
Cdd:PRK04863 273 DYMRHANERRVHLEEALELRRELytsRRQLAAEQYRLVEMARELAEL----NEAESDLEQDYQAASD----HLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 657 ELTKKLtAKSRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLEnsrltadLSAQLqtlASTENELKELQ--- 733
Cdd:PRK04863 345 RQQEKI-ERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDE-------LKSQL---ADYQQALDVQQtra 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 734 SQHSHCVQDLAmKDELLCQ---LTQSN-KEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVdeESQVAHLE 809
Cdd:PRK04863 414 IQYQQAVQALE-RAKQLCGlpdLTADNaEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLV--RKIAGEVS 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 810 LGQIESQLKATLEVLRERSLQCETLkdtvESLRAELASTEAKHEQQA-----LEKTHQHSKELCLLAEQLQSLTLFLEAK 884
Cdd:PRK04863 491 RSEAWDVARELLRRLREQRHLAEQL----QQLRMRLSELEQRLRQQQraerlLAEFCKRLGKNLDDEDELEQLQEELEAR 566
|
....*..
gi 112984402 885 LEENKAE 891
Cdd:PRK04863 567 LESLSES 573
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
700-895 |
4.34e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.04 E-value: 4.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 700 QIEQLKLENSRLTADLSAQLQTLASTENELKELQSQhshcvqdlamkdellcqlTQSNKEQAAQWQKEETELKHRQAELL 779
Cdd:COG4372 39 ELDKLQEELEQLREELEQAREELEQLEEELEQARSE------------------LEQLEEELEELNEQLQAAQAELAQAQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 780 QQKAVLAKEVQDLRETMEFVDEESQVAHLELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALEK 859
Cdd:COG4372 101 EELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAE 180
|
170 180 190
....*....|....*....|....*....|....*.
gi 112984402 860 THQHSKELCLLAEQLQSLTLFLEAKLEENKAESDII 895
Cdd:COG4372 181 AEQALDELLKEANRNAEKEEELAEAEKLIESLPREL 216
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
653-1179 |
4.72e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.16 E-value: 4.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 653 SRSRELTKKLTAKSRQALQERDAAIEEKDqvvkEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKEL 732
Cdd:TIGR04523 211 QKNKSLESQISELKKQNNQLKDNIEKKQQ----EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKEL 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 733 QSQhshcVQDLAMKDELLCQLTQSN-----KEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESQVAH 807
Cdd:TIGR04523 287 EKQ----LNQLKSEISDLNNQKEQDwnkelKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 808 LELGQIESQLKATLEVLRERSLQCETLKDTVESLRAELASTEaKHEQQALEKTHQHSKELCLLAEQLQSLTLFLE----- 882
Cdd:TIGR04523 363 RELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQE-KLNQQKDEQIKKLQQEKELLEKEIERLKETIIknnse 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 883 -AKLEENKAESDIILPSTGcapaqehppSSDSSVSEQIPTavvdevpepapvpLLGSVKSAFTRvastapfrptetpaLE 961
Cdd:TIGR04523 442 iKDLTNQDSVKELIIKNLD---------NTRESLETQLKV-------------LSRSINKIKQN--------------LE 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 962 KSLAEMSAVLQELQRLCALLQESKEEaVGVLQREICELHTRLQAQEEEHQEAQ---KAKEADIEKLNQALclrhkNEKEL 1038
Cdd:TIGR04523 486 QKQKELKSKEKELKKLNEEKKELEEK-VKDLTKKISSLKEKIEKLESEKKEKEskiSDLEDELNKDDFEL-----KKENL 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 1039 LEVIQKQNEKI--LGQIDTSgqlinLREEVTQLTRLLRRAETETKVLQEALEgqvdpscqlmatNWIQEKVFLSQEVNKL 1116
Cdd:TIGR04523 560 EKEIDEKNKEIeeLKQTQKS-----LKKKQEEKQELIDQKEKEKKDLIKEIE------------EKEKKISSLEKELEKA 622
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 112984402 1117 RAmflevKNEKkqlmdkylshrhiLEENLRRSDTELKKLDDTIQHIYETLLSI----PEVVKSCKEL 1179
Cdd:TIGR04523 623 KK-----ENEK-------------LSSIIKNIKSKKNKLKQEVKQIKETIKEIrnkwPEIIKKIKES 671
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
589-893 |
5.23e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.16 E-value: 5.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 589 ISQLEQGITSVQEfrgLLQEAQTQLIGLHTEQEELAQHtvsltsaLQQDWTSVQQNYGTWAALLSRSRELTKKLTAKSRQ 668
Cdd:TIGR04523 234 IEKKQQEINEKTT---EISNTQTQLNQLKDEQNKIKKQ-------LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 669 ALQERDAAI--------EEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHShcv 740
Cdd:TIGR04523 304 KEQDWNKELkselknqeKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQ--- 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 741 qdlAMKDELLCQLTQSNK-EQAAQWQKEETELKHRQAELLQQ-KAVLAKEVQDLRETMEFVDEE-----SQVAHLE---- 809
Cdd:TIGR04523 381 ---SYKQEIKNLESQINDlESKIQNQEKLNQQKDEQIKKLQQeKELLEKEIERLKETIIKNNSEikdltNQDSVKEliik 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 810 -LGQIESQLKATLEVLrerSLQCETLKDTVESLRAELASTEAKHEQQALEKThQHSKELCLLAEQLQSLTLFLEaKLEEN 888
Cdd:TIGR04523 458 nLDNTRESLETQLKVL---SRSINKIKQNLEQKQKELKSKEKELKKLNEEKK-ELEEKVKDLTKKISSLKEKIE-KLESE 532
|
....*
gi 112984402 889 KAESD 893
Cdd:TIGR04523 533 KKEKE 537
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
527-858 |
5.38e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 5.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 527 QESQRAETLVSSCSRVLKKLRAKLQSLKTEWEEARHREEMALKGKDAAEAVLEAFRAHASQRISQLEQGITSVQEFRGLL 606
Cdd:COG4717 132 QELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAEL 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 607 QEAQTQLiglhteQEELAQHTVSLTSALQQDWTSVQQN------------------YGTWAALLSRSRELTKKLTAK--- 665
Cdd:COG4717 212 EEELEEA------QEELEELEEELEQLENELEAAALEErlkearlllliaaallalLGLGGSLLSLILTIAGVLFLVlgl 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 666 ----SRQALQERDAAIEEKDQVVKEVEQVSAHLEDCKGQIEQLKLENSRLTADLSAQLQTLASTENELKELQSQHSH--C 739
Cdd:COG4717 286 lallFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElqL 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 740 VQDLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEFVDEESqvAHLELGQIESQLKA 819
Cdd:COG4717 366 EELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE--LEEELEELEEELEE 443
|
330 340 350
....*....|....*....|....*....|....*....
gi 112984402 820 TLEVLRERSLQCETLKDTVESLRAELASTEAKHEQQALE 858
Cdd:COG4717 444 LEEELEELREELAELEAELEQLEEDGELAELLQELEELK 482
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
543-781 |
6.02e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.05 E-value: 6.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 543 LKKLRAKLQSLKTEWEEARhREEMALKgKDAAEAVLEAFrahASQRISQLEQGITSVQEfrgLLQEAQ-------TQLIG 615
Cdd:PRK11281 82 TEQLKQQLAQAPAKLRQAQ-AELEALK-DDNDEETRETL---STLSLRQLESRLAQTLD---QLQNAQndlaeynSQLVS 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 616 LHTeQEELAQhtVSLTSALQQdwtsVQQnygtWAALLSRSRELTKKLTAKSRQALQERDAAIEekdqvvkeveqvsahle 695
Cdd:PRK11281 154 LQT-QPERAQ--AALYANSQR----LQQ----IRNLLKGGKVGGKALRPSQRVLLQAEQALLN----------------- 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 696 dckgqieqLKLENSRLTADLSAQLQTLASTENELKELQSQHS-HCVQDLamkDELLCQ--LTQSnKEQAAQWQKEETELK 772
Cdd:PRK11281 206 --------AQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLeHQLQLL---QEAINSkrLTLS-EKTVQEAQSQDEAAR 273
|
....*....
gi 112984402 773 HRQAELLQQ 781
Cdd:PRK11281 274 IQANPLVAQ 282
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
668-887 |
6.62e-03 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 39.35 E-value: 6.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 668 QALQERDAAIEEKDQVVKEvEQVSAHLEDCKGQIEQLKlensRLTADLSAQLQTLASTENELKELQSQHSHCVQDLAMKD 747
Cdd:cd00176 7 RDADELEAWLSEKEELLSS-TDYGDDLESVEALLKKHE----ALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 748 ELLCQLTQSNKEQAAQWQKEetelkhrqaelLQQKAVLAKEVQDLRETMEFVDE-ESQVAHLELGQIESQLKATLEVLRE 826
Cdd:cd00176 82 EELNQRWEELRELAEERRQR-----------LEEALDLQQFFRDADDLEQWLEEkEAALASEDLGKDLESVEELLKKHKE 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 112984402 827 RSLQCETLKDTVESLRAELASTEAKHEQQALEKTHQHSKELCLLAEQLQSLTLFLEAKLEE 887
Cdd:cd00176 151 LEEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
660-873 |
9.02e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.15 E-value: 9.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 660 KKLTAKSRQALQERDAAIEEKDqvvKEVEQVSahledcKGQIEQLKLENSRLTADLSAQLQtlaSTENELKELQSQhshc 739
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRILEEAK---KEAEAIK------KEALLEAKEEIHKLRNEFEKELR---ERRNELQKLEKR---- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 112984402 740 vqdLAMKDELLCQLTQSNKEQAAQWQKEETELKHRQAELLQQKAVLAKEVQDLRETMEfvdeesQVAHLELGQIESQLka 819
Cdd:PRK12704 91 ---LLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELE------RISGLTAEEAKEIL-- 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 112984402 820 tlevlrerslqcetLKDTVESLRAELASTEAKHEQQALEKTHQHSKELCLLAEQ 873
Cdd:PRK12704 160 --------------LEKVEEEARHEAAVLIKEIEEEAKEEADKKAKEILAQAIQ 199
|
|
| |
