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Conserved domains on  [gi|116007678|ref|NP_001036535|]
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bruchpilot, isoform H [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cast super family cl37807
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 114-705 2.85e-61

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


The actual alignment was detected with superfamily member pfam10174:

Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 225.86  E-value: 2.85e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   114 LQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLE 193
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   194 EELRLRmRQPNLEMQQQMEA---------------------IYAENDHLQREISILRETIKDLECRVETQKQTLIARDES 252
Cdd:pfam10174   81 DELRAQ-RDLNQLLQQDFTTspvdgedkfstpelteenfrrLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDES 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   253 IKKLLEMLQAKGMGK----------------------------------------------------------------- 267
Cdd:pfam10174  160 IKKLLEMLQSKGLPKksgeedwertrriaeaemqlghlevlldqkekenihlreelhrrnqlqpdpaktkalqtviemkd 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   268 -------------EEERQMFQQMQAMAQKQ---------------------LDEFRLEIQRRDQEILAMAAKMKTLEEQH 313
Cdd:pfam10174  240 tkisslernirdlEDEVQMLKTNGLLHTEDreeeikqmevykshskfmknkIDQLKQELSKKESELLALQTKLETLTNQN 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   314 QDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVL 393
Cdd:pfam10174  320 SDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVL 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   394 QRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVAD 473
Cdd:pfam10174  400 QKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKD 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   474 YKIKLRAaeseveklqtrLERAVTERERLEIKLEASQSELGKSKAELEkatcemgrssadwestkQRIARLELENERLKH 553
Cdd:pfam10174  480 LKEKVSA-----------LQPELTEKESSLIDLKEHASSLASSGLKKD-----------------SKLKSLEIAVEQKKE 531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   554 DLERSQNVQKL---MFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEK 630
Cdd:pfam10174  532 ECSKLENQLKKahnAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLR 611

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678   631 SQGEVYRLKAKLE-NAQGEQESLRQELEKAQSgvSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 705
Cdd:pfam10174  612 QMKEQNKKVANIKhGQQEMKKKGAQLLEEARR--REDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSL 685
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 372-1161 5.82e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.53  E-value: 5.82e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   372 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 451
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   452 QRDRAEHEKQEerdlHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSS 531
Cdd:TIGR02168  310 RLANLERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   532 ADWESTKQRIARLELENERLKHDLERSQ-NVQKLMFETGKISTTFGRTTMTTSQ-ELDRAQERADKASAELRRTQAELRV 609
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEdRRERLQQEIEELLKKLEEAELKELQaELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   610 TQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAqsgvSRIHADRDRAfSEVEKIKEEMERTQA 689
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ----SGLSGILGVL-SELISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   690 TLGKSQLQHeKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLS---- 765
Cdd:TIGR02168  541 AALGGRLQA-VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkals 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   766 --LDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKER------SESAQTLLMKAARDREAMQTDLEVLKERYEKSHAI 837
Cdd:TIGR02168  620 ylLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   838 QQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAER 917
Cdd:TIGR02168  700 LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   918 SGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTY 997
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   998 ELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELE 1076
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrSELRRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1077 TIRGK-SQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLElSKGEVAKM----LANQEKQRSELERAHIEREKARDK 1151
Cdd:TIGR02168  940 NLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAaieeYEELKERYDFLTAQKEDLTEAKET 1018

                          810
                   ....*....|
gi 116007678  1152 HEKLLKEVDR 1161
Cdd:TIGR02168 1019 LEEAIEEIDR 1028
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 963-1711 1.25e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   963 ELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELR 1042
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1043 KLQdtdtfgRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKG 1122
Cdd:TIGR02168  313 NLE------RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1123 EVAKMLANQEKQRSELERAHIE-------REKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIdR 1195
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARlerledrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE-E 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1196 LRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEF---ERMGAELGRLHDRLEkAEAEREALRQANRS 1272
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknqSGLSGILGVLSELIS-VDEGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1273 GGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAE------AELQKTREENRKLRNG---- 1342
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1343 -HQVPPVAAPPAGPSPAEFQAMqkeIQTLQQKLQeseRALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADK 1421
Cdd:TIGR02168  625 vLVVDDLDNALELAKKLRPGYR---IVTLDGDLV---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1422 AAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVqqaaqqqqsaagaggadpKELEKVRGELQAACTERDRFQ 1501
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE------------------AEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1502 QQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQI 1581
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1582 DNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQL 1661
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 116007678  1662 EACVKELQNTKEEHK-KAATETERLLQLVQMSQEEQNAKEKTIMDLQQALK 1711
Cdd:TIGR02168  921 REKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 114-705 2.85e-61

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 225.86  E-value: 2.85e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   114 LQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLE 193
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   194 EELRLRmRQPNLEMQQQMEA---------------------IYAENDHLQREISILRETIKDLECRVETQKQTLIARDES 252
Cdd:pfam10174   81 DELRAQ-RDLNQLLQQDFTTspvdgedkfstpelteenfrrLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDES 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   253 IKKLLEMLQAKGMGK----------------------------------------------------------------- 267
Cdd:pfam10174  160 IKKLLEMLQSKGLPKksgeedwertrriaeaemqlghlevlldqkekenihlreelhrrnqlqpdpaktkalqtviemkd 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   268 -------------EEERQMFQQMQAMAQKQ---------------------LDEFRLEIQRRDQEILAMAAKMKTLEEQH 313
Cdd:pfam10174  240 tkisslernirdlEDEVQMLKTNGLLHTEDreeeikqmevykshskfmknkIDQLKQELSKKESELLALQTKLETLTNQN 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   314 QDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVL 393
Cdd:pfam10174  320 SDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVL 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   394 QRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVAD 473
Cdd:pfam10174  400 QKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKD 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   474 YKIKLRAaeseveklqtrLERAVTERERLEIKLEASQSELGKSKAELEkatcemgrssadwestkQRIARLELENERLKH 553
Cdd:pfam10174  480 LKEKVSA-----------LQPELTEKESSLIDLKEHASSLASSGLKKD-----------------SKLKSLEIAVEQKKE 531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   554 DLERSQNVQKL---MFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEK 630
Cdd:pfam10174  532 ECSKLENQLKKahnAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLR 611

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678   631 SQGEVYRLKAKLE-NAQGEQESLRQELEKAQSgvSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 705
Cdd:pfam10174  612 QMKEQNKKVANIKhGQQEMKKKGAQLLEEARR--REDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSL 685
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 372-1161 5.82e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.53  E-value: 5.82e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   372 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 451
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   452 QRDRAEHEKQEerdlHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSS 531
Cdd:TIGR02168  310 RLANLERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   532 ADWESTKQRIARLELENERLKHDLERSQ-NVQKLMFETGKISTTFGRTTMTTSQ-ELDRAQERADKASAELRRTQAELRV 609
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEdRRERLQQEIEELLKKLEEAELKELQaELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   610 TQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAqsgvSRIHADRDRAfSEVEKIKEEMERTQA 689
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ----SGLSGILGVL-SELISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   690 TLGKSQLQHeKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLS---- 765
Cdd:TIGR02168  541 AALGGRLQA-VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkals 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   766 --LDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKER------SESAQTLLMKAARDREAMQTDLEVLKERYEKSHAI 837
Cdd:TIGR02168  620 ylLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   838 QQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAER 917
Cdd:TIGR02168  700 LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   918 SGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTY 997
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   998 ELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELE 1076
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrSELRRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1077 TIRGK-SQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLElSKGEVAKM----LANQEKQRSELERAHIEREKARDK 1151
Cdd:TIGR02168  940 NLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAaieeYEELKERYDFLTAQKEDLTEAKET 1018

                          810
                   ....*....|
gi 116007678  1152 HEKLLKEVDR 1161
Cdd:TIGR02168 1019 LEEAIEEIDR 1028
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 592-1121 6.05e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 87.30  E-value: 6.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  592 RADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRD 671
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  672 RAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKAL 751
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  752 GQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERY 831
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  832 EKSHAIQQKLQMERDDAVTEVEILKEKLD-----------KALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSR 900
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEAdyegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  901 CDTAEADRARLEVEAERSGLAASKAREDL---RKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRfDKLQTD 977
Cdd:COG1196   553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKiraRAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR-TLVAAR 631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  978 IRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAhyavELEKMRDRYEKSQVELRKLQDTDTFGRETRRL 1057
Cdd:COG1196   632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL----EAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678 1058 KEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSK 1121
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 287-861 2.12e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 2.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  287 EFRLEIQRRDQEILAMA-----AKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQG 361
Cdd:COG1196   217 ELKEELKELEAELLLLKlreleAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  362 TLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGD 441
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  442 KEKQMAQLRDQRDRAEHEKQEERDL---HEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKA 518
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQleeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  519 ELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMfetgkisttFGRTTMTTSQELDRAQERADKASA 598
Cdd:COG1196   457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY---------EGFLEGVKAALLLAGLRGLAGAVA 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  599 ELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVE 678
Cdd:COG1196   528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  679 KIKEEMERTQatlgksqlqhekLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQ 758
Cdd:COG1196   608 LREADARYYV------------LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  759 KERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQ 838
Cdd:COG1196   676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                         570       580
                  ....*....|....*....|...
gi 116007678  839 QKLQMERDDAVTEVEILKEKLDK 861
Cdd:COG1196   756 LPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 198-945 3.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.17  E-value: 3.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   198 LRMRQPNLEMQ----QQMEAIYAENDHLQREISILRetIKDLECRVETQKQTLIA---RDESIKKLLEMLQAKGMGKEEE 270
Cdd:TIGR02168  198 LERQLKSLERQaekaERYKELKAELRELELALLVLR--LEELREELEELQEELKEaeeELEELTAELQELEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   271 RQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTL-------EEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEE 343
Cdd:TIGR02168  276 VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLerqleelEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   344 MRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKdhmdikdRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQA 423
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLE-------LQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   424 hhSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEK---QEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERE 500
Cdd:TIGR02168  429 --KLEEAELKELQAELEELEEELEELQEELERLEEALeelREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   501 RL-EIKLEASQ--------SELGKSKAELEKATCEMGRSSA------DWESTKQRIARLE---------LENERLKHDLE 556
Cdd:TIGR02168  507 GVkALLKNQSGlsgilgvlSELISVDEGYEAAIEAALGGRLqavvveNLNAAKKAIAFLKqnelgrvtfLPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   557 RSQNVQKLMFETGKISTTFGRTTMTTS---------------QELDRAQERADKASAELR-------------------- 601
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsa 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   602 RTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIK 681
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   682 EEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKER 761
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   762 ETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKshaiqqkl 841
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE-------- 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   842 qmerddavteveiLKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCdtaeadRARLEVEAERSGLA 921
Cdd:TIGR02168  899 -------------LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEAEAL 959

                          810       820
                   ....*....|....*....|....
gi 116007678   922 ASKAREDLRKLQDESTRLQEACDR 945
Cdd:TIGR02168  960 ENKIEDDEEEARRRLKRLENKIKE 983
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
761-1266 2.36e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 68.91  E-value: 2.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  761 RETLSLDTDRIREKLEKTQV-QLGRIQKERDQFSDELETLKERSESAQTLLMKAA---RDREAMQTDLEVLKERYEKSHA 836
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDLHeRLNGLESELAELDEEIERYEEQREQARETRDEADevlEEHEERREELETLEAEIEDLRE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  837 IQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAE 916
Cdd:PRK02224  266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  917 RSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERV- 995
Cdd:PRK02224  346 SLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELr 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  996 ------TYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgrETRRLKEENERLREKLD 1069
Cdd:PRK02224  426 ereaelEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEA------ELEDLEEEVEEVEERLE 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1070 ktlmeletiRGKSQYESES-FEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKA 1148
Cdd:PRK02224  500 ---------RAEDLVEAEDrIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEA 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1149 RD-------KHEKLLKEVDRLRLQQSSVSP----GDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRL 1217
Cdd:PRK02224  571 REevaelnsKLAELKERIESLERIRTLLAAiadaEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEE 650

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 116007678 1218 AKE-LEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREAL 1266
Cdd:PRK02224  651 AREdKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERR 700
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
431-976 1.64e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.14  E-value: 1.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  431 ALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHErEVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQ 510
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLR 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  511 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKlmfetgkistTFGRTTMTTSQELDRAQ 590
Cdd:PRK02224  286 ERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ----------AHNEEAESLREDADDLE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  591 ERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADR 670
Cdd:PRK02224  356 ERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATL 435

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  671 DRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLtydydnlqSQLDKA 750
Cdd:PRK02224  436 RTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA--------EDLVEA 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  751 LGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKER 830
Cdd:PRK02224  508 EDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKER 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  831 YEKSHAIQQKLQmERDDAVTEVEILKEKLDKalyasqklIDEKDTSNKefEKMLEKYDRAQNEIYRLQ-SRCDTAEADRA 909
Cdd:PRK02224  588 IESLERIRTLLA-AIADAEDEIERLREKREA--------LAELNDERR--ERLAEKRERKRELEAEFDeARIEEAREDKE 656

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116007678  910 RLEVEAErsglaasKAREDLRKLQDESTRLQEACDRAALQLSRAKECednaRSELEHSRDRFDKLQT 976
Cdd:PRK02224  657 RAEEYLE-------QVEEKLDELREERDDLQAEIGAVENELEELEEL----RERREALENRVEALEA 712
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 963-1711 1.25e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   963 ELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELR 1042
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1043 KLQdtdtfgRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKG 1122
Cdd:TIGR02168  313 NLE------RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1123 EVAKMLANQEKQRSELERAHIE-------REKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIdR 1195
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARlerledrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE-E 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1196 LRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEF---ERMGAELGRLHDRLEkAEAEREALRQANRS 1272
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknqSGLSGILGVLSELIS-VDEGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1273 GGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAE------AELQKTREENRKLRNG---- 1342
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1343 -HQVPPVAAPPAGPSPAEFQAMqkeIQTLQQKLQeseRALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADK 1421
Cdd:TIGR02168  625 vLVVDDLDNALELAKKLRPGYR---IVTLDGDLV---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1422 AAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVqqaaqqqqsaagaggadpKELEKVRGELQAACTERDRFQ 1501
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE------------------AEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1502 QQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQI 1581
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1582 DNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQL 1661
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 116007678  1662 EACVKELQNTKEEHK-KAATETERLLQLVQMSQEEQNAKEKTIMDLQQALK 1711
Cdd:TIGR02168  921 REKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1095-1670 5.02e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 5.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1095 KYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQssvspgDP 1174
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI------AR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1175 VRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHD 1254
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1255 RLEKAEAEREALRQANRsggagaaphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTRE 1334
Cdd:COG1196   387 ELLEALRAAAELAAQLE----------ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1335 ENRKLRnghqvppvaaPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASRE--EIEQWRKVIEQE 1412
Cdd:COG1196   457 EEEALL----------ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalLLAGLRGLAGAV 526

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1413 KSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQA 1492
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1493 ACTERDRFQQQLELLVTElekskmSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQK 1572
Cdd:COG1196   607 DLREADARYYVLGDTLLG------RTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1573 QLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNK 1652
Cdd:COG1196   681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                         570
                  ....*....|....*...
gi 116007678 1653 KLMDTQRQLeacvKELQN 1670
Cdd:COG1196   761 DLEELEREL----ERLER 774
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 353-1164 3.25e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   353 RLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGAL 432
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   433 T----SLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA 508
Cdd:pfam02463  249 EqeeiESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   509 SQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKIstTFGRTTMTTSQELDR 588
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK--LKEEELELKSEEEKE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   589 AQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGE---QESLRQELEKAQSGVSR 665
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELElkkSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   666 IHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKA--CTENRRLVLEKEKLTYDYDNL 743
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVaiSTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   744 QSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQK-----ERDQFSDELETLKERSESAQTLLMKAARDRE 818
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKatleaDEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   819 AMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQ 898
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   899 SRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH-SRDRFDKLQTD 977
Cdd:pfam02463  727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEkLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   978 IRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRL 1057
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1058 KEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSE 1137
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820
                   ....*....|....*....|....*..
gi 116007678  1138 LERAHIEREKARDKHEKLLKEVDRLRL 1164
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKD 993
PTZ00121 PTZ00121
MAEBL; Provisional
 977-1711 9.08e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 9.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  977 DIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRR 1056
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARK 1165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1057 LKEENERLREKLDKTLMELETIRgksqyESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRS 1136
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVR-----KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1137 ELERAHIEREKARDKHEKLLKEVDRLRLQQSSVS----PGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATEL 1212
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAeearKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1213 EagrlaKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLEs 1292
Cdd:PTZ00121 1321 K-----KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD- 1394

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1293 DVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEA-----ELQKTREENRKlrnGHQVPPVAAPPAGPSPAEFQAMQKEI 1367
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkkadEAKKKAEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1368 QTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIE----QEKSRADMADKAaqEMHKRIQLMDQHIKDQHAQ 1443
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKA--EEAKKADEAKKAEEKKKAD 1549

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1444 MQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTELEKSKmsnQEQAK 1523
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK---AEELK 1626

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1524 QLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQID 1603
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1604 AKRKDIEEKekkmaefdvqlrKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETE 1683
Cdd:PTZ00121 1707 LKKKEAEEK------------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                         730       740
                  ....*....|....*....|....*...
gi 116007678 1684 RLLQLVqMSQEEQNAKEKTIMDLQQALK 1711
Cdd:PTZ00121 1775 KEKEAV-IEEELDEEDEKRRMEVDKKIK 1801
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 757-1652 6.09e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 6.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   757 MQKERETLSLDTD----RIREKLEKTQVQLGRIQKERDQFSDELETLKERSESaqTLLMKAARDREAMQTDLEVLKERYE 832
Cdd:pfam02463  149 MMKPERRLEIEEEaagsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELK--LKEQAKKALEYYQLKEKLELEEEYL 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   833 KSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLE 912
Cdd:pfam02463  227 LYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLE 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   913 VEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSEL 992
Cdd:pfam02463  307 RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   993 ERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTdtfgretrrlKEENERLREKLDKTL 1072
Cdd:pfam02463  387 SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIEL----------KQGKLTEEKEELEKQ 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1073 MELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKH 1152
Cdd:pfam02463  457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1153 EKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKA-LQSRDATELEAGRLAKELEKAQMHLAKQ 1231
Cdd:pfam02463  537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLkLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1232 QENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLesDVKQLAMEREQLVLQLEKS 1311
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL--LEIQELQEKAESELAKEEI 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1312 QEILMNFQKELQNAEAELQKTREENRKLRNGhqvppVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQA 1391
Cdd:pfam02463  695 LRRQLEIKKKEQREKEELKKLKLEAEELLAD-----RVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1392 AAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQS 1471
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1472 aagaggadpKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQ 1551
Cdd:pfam02463  850 ---------KLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIE 920

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1552 AASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMD 1631
Cdd:pfam02463  921 ERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000

                          890       900
                   ....*....|....*....|.
gi 116007678  1632 QLEKSLQTQGGGAAAAGELNK 1652
Cdd:pfam02463 1001 EEEKKKLIRAIIEETCQRLKE 1021
 
Name Accession Description Interval E-value
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 114-705 2.85e-61

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 225.86  E-value: 2.85e-61
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   114 LQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLE 193
Cdd:pfam10174    1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQ 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   194 EELRLRmRQPNLEMQQQMEA---------------------IYAENDHLQREISILRETIKDLECRVETQKQTLIARDES 252
Cdd:pfam10174   81 DELRAQ-RDLNQLLQQDFTTspvdgedkfstpelteenfrrLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDES 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   253 IKKLLEMLQAKGMGK----------------------------------------------------------------- 267
Cdd:pfam10174  160 IKKLLEMLQSKGLPKksgeedwertrriaeaemqlghlevlldqkekenihlreelhrrnqlqpdpaktkalqtviemkd 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   268 -------------EEERQMFQQMQAMAQKQ---------------------LDEFRLEIQRRDQEILAMAAKMKTLEEQH 313
Cdd:pfam10174  240 tkisslernirdlEDEVQMLKTNGLLHTEDreeeikqmevykshskfmknkIDQLKQELSKKESELLALQTKLETLTNQN 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   314 QDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVL 393
Cdd:pfam10174  320 SDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVL 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   394 QRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVAD 473
Cdd:pfam10174  400 QKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELESLKKENKD 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   474 YKIKLRAaeseveklqtrLERAVTERERLEIKLEASQSELGKSKAELEkatcemgrssadwestkQRIARLELENERLKH 553
Cdd:pfam10174  480 LKEKVSA-----------LQPELTEKESSLIDLKEHASSLASSGLKKD-----------------SKLKSLEIAVEQKKE 531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   554 DLERSQNVQKL---MFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEK 630
Cdd:pfam10174  532 ECSKLENQLKKahnAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLR 611

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678   631 SQGEVYRLKAKLE-NAQGEQESLRQELEKAQSgvSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 705
Cdd:pfam10174  612 QMKEQNKKVANIKhGQQEMKKKGAQLLEEARR--REDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSL 685
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 372-1161 5.82e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 110.53  E-value: 5.82e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   372 LTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRD 451
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   452 QRDRAEHEKQEerdlHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSS 531
Cdd:TIGR02168  310 RLANLERQLEE----LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   532 ADWESTKQRIARLELENERLKHDLERSQ-NVQKLMFETGKISTTFGRTTMTTSQ-ELDRAQERADKASAELRRTQAELRV 609
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEdRRERLQQEIEELLKKLEEAELKELQaELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   610 TQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAqsgvSRIHADRDRAfSEVEKIKEEMERTQA 689
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ----SGLSGILGVL-SELISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   690 TLGKSQLQHeKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLS---- 765
Cdd:TIGR02168  541 AALGGRLQA-VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkals 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   766 --LDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKER------SESAQTLLMKAARDREAMQTDLEVLKERYEKSHAI 837
Cdd:TIGR02168  620 ylLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   838 QQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAER 917
Cdd:TIGR02168  700 LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   918 SGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTY 997
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   998 ELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT-DTFGRETRRLKEENERLREKLDKTLMELE 1076
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKrSELRRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1077 TIRGK-SQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLElSKGEVAKM----LANQEKQRSELERAHIEREKARDK 1151
Cdd:TIGR02168  940 NLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK-ELGPVNLAaieeYEELKERYDFLTAQKEDLTEAKET 1018

                          810
                   ....*....|
gi 116007678  1152 HEKLLKEVDR 1161
Cdd:TIGR02168 1019 LEEAIEEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 427-1269 7.99e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 106.68  E-value: 7.99e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   427 SSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKL 506
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   507 EASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKlmfetgkisttfgrttmTTSQEL 586
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE-----------------ELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   587 DRAQERADKASAELRRTQAELRVTQsdaerarEEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRI 666
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELK-------EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   667 HADRDRAFSEVEKIKEEMERTQATlgKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQ 746
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQE--IEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQA 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   747 LDKALGQAARMQKERETLsldtDRIREKLEKTQVQLGRIQKERDQFSDELETLKER---------------SESAQTLLM 811
Cdd:TIGR02168  477 LDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyeaaieaalGGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   812 KaarDREAMQTDLEVLKE-RYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQkLIDEKDTSNKEFEKML------ 884
Cdd:TIGR02168  553 E---NLNAAKKAIAFLKQnELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKD-LVKFDPKLRKALSYLLggvlvv 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   885 EKYDRAQNEI--YRLQSRCDTAEADRARleveaeRSGL---AASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDN 959
Cdd:TIGR02168  629 DDLDNALELAkkLRPGYRIVTLDGDLVR------PGGVitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   960 ARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQV 1039
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1040 ELRKLQdtdtfgRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLEL 1119
Cdd:TIGR02168  783 EIEELE------AQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1120 SKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLrlqqssvspgdpvrastssssalsageRQEIDRLRDR 1199
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL---------------------------SEELRELESK 909

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116007678  1200 LEKALQSRDATELEAGRLAKELEKAQMHLAKQQEN-TESTRIEFERMGAELGRLHDRLEKAEAEREALRQA 1269
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 451-1267 4.55e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 91.28  E-value: 4.55e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   451 DQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKatcemgrs 530
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALER-------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   531 saDWESTKQRIARLELENERLkhDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVT 610
Cdd:TIGR02169  238 --QKEAIERQLASLEEELEKL--TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   611 QSdaerareEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQAT 690
Cdd:TIGR02169  314 ER-------ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   691 LGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDR 770
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   771 IREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLE----------VLKERYEK------S 834
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlgSVGERYATaievaaG 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   835 HAIQQKLQMERDDAVTEVEILKEKldKALYASQKLIDEKDTSNKEFEKMLE---------------KYDRAQNEIYR--- 896
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRR--KAGRATFLPLNKMRDERRDLSILSEdgvigfavdlvefdpKYEPAFKYVFGdtl 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   897 LQSRCDTAEA--DRARLEVEA----ERSG------LAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSEL 964
Cdd:TIGR02169  625 VVEDIEAARRlmGKYRMVTLEgelfEKSGamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   965 EHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKL 1044
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1045 QD--TDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKG 1122
Cdd:TIGR02169  785 EArlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1123 EVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSpgDPVRASTSSSSALSAGERQEIDRLrDRLEK 1202
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQI--EKKRKRLSELKAKLEALEEELSEI-EDPKG 941

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116007678  1203 ALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALR 1267
Cdd:TIGR02169  942 EDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 592-1121 6.05e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 87.30  E-value: 6.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  592 RADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRD 671
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  672 RAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKAL 751
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  752 GQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERY 831
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  832 EKSHAIQQKLQMERDDAVTEVEILKEKLD-----------KALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSR 900
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEAdyegflegvkaALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  901 CDTAEADRARLEVEAERSGLAASKAREDL---RKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRfDKLQTD 977
Cdd:COG1196   553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKiraRAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR-TLVAAR 631

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  978 IRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAhyavELEKMRDRYEKSQVELRKLQDTDTFGRETRRL 1057
Cdd:COG1196   632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL----EAEAELEELAERLAEEELELEEALLAEEEEER 707

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678 1058 KEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSK 1121
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 592-1376 1.54e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 1.54e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   592 RADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSgvsrihadrd 671
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ---------- 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   672 rafsEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKAL 751
Cdd:TIGR02168  303 ----QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   752 GQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQtlLMKAARDREAMQTDLEVLKERY 831
Cdd:TIGR02168  379 EQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   832 EKSHAIQQKLQMERDDAVTEVEILKEKLDKA---LYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADR 908
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLqarLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYE 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   909 ARLEVeAERSGLAASKAREDLRKLQDESTRLQEACDRAA-LQLSRAKECEDNArselehSRDRFDKLQTDIRRAQGEKEH 987
Cdd:TIGR02168  537 AAIEA-ALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTfLPLDSIKGTEIQG------NDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   988 FQSELERV-TYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGR--ETRRLKEENERL 1064
Cdd:TIGR02168  610 FDPKLRKAlSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERrrEIEELEEKIEEL 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1065 REKLDKTLMELETIRgksqyesESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIE 1144
Cdd:TIGR02168  690 EEKIAELEKALAELR-------KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1145 REKARDKHEKLLKEVDRLRLQQSSVSPG-DPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEK 1223
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1224 AQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSggagaaphpqLEKHVQKLESDVKQLAMEREQ 1303
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL----------LRSELEELSEELRELESKRSE 912

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678  1304 LVLQLEKSQEILMNFQKELQNAEAELQKTREenrKLRNGHQVPPVA-APPAGPSPAEFQAMQKEIQTLQQKLQE 1376
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQE---RLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 287-861 2.12e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 2.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  287 EFRLEIQRRDQEILAMA-----AKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQG 361
Cdd:COG1196   217 ELKEELKELEAELLLLKlreleAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  362 TLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGD 441
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  442 KEKQMAQLRDQRDRAEHEKQEERDL---HEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKA 518
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQleeLEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  519 ELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMfetgkisttFGRTTMTTSQELDRAQERADKASA 598
Cdd:COG1196   457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY---------EGFLEGVKAALLLAGLRGLAGAVA 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  599 ELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVE 678
Cdd:COG1196   528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  679 KIKEEMERTQatlgksqlqhekLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQ 758
Cdd:COG1196   608 LREADARYYV------------LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALL 675

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  759 KERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQ 838
Cdd:COG1196   676 EAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEE 755

                         570       580
                  ....*....|....*....|...
gi 116007678  839 QKLQMERDDAVTEVEILKEKLDK 861
Cdd:COG1196   756 LPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 774-1516 3.51e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 3.51e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   774 KLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAmqtDLEVLKERYEKSHAIQQKLQMERDDAVTEVE 853
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELREL---ELALLVLRLEELREELEELQEELKEAEEELE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   854 ILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRL-------QSRCDTAEADRARLEVEAERSGLAASKAR 926
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeqqkqilRERLANLERQLEELEAQLEELESKLDELA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   927 EDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQ 1006
Cdd:TIGR02168  337 EELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1007 TKASASVEAAKEEAAhyAVELEKMRDRYEKSQVELRKLQDTDTFGRET-RRLKEENERLREKLDKTLMELETIRGKSQYE 1085
Cdd:TIGR02168  417 ERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEAlEELREELEEAEQALDAAERELAQLQARLDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1086 SESFEKYKDKYEKIEMEVQNmesklhetSLQLELSKGEVAKMLANQEKQRSELERA--------HIEREKARDKHEKLLK 1157
Cdd:TIGR02168  495 ERLQENLEGFSEGVKALLKN--------QSGLSGILGVLSELISVDEGYEAAIEAAlggrlqavVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1158 EVDRLR---LQQSSVSPGDP--VRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATEL------EAGRLAKELEKAQM 1226
Cdd:TIGR02168  567 QNELGRvtfLPLDSIKGTEIqgNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYR 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1227 HLAKQQEN-TESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGgagaaphpQLEKHVQKLESDVKQLAMEREQLV 1305
Cdd:TIGR02168  647 IVTLDGDLvRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIA--------ELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1306 LQLEKSQEILMNFQKELQNAEAELQKTREENRKLR----NGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERAL 1381
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSkeltELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1382 QAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQA 1461
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 116007678  1462 VQQAAQQQQSAAGAGgadpKELEKVRGELQAACTERDRFQQQLELLVTELEKSKM 1516
Cdd:TIGR02168  879 LNERASLEEALALLR----SELEELSEELRELESKRSELRRELEELREKLAQLEL 929
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 650-1375 7.08e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 7.08e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   650 ESLRQELEKAqSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQ------------------NE 711
Cdd:TIGR02168  155 EERRAIFEEA-AGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAErykelkaelrelelallvLR 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   712 VDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQ 791
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   792 FSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLID 871
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   872 EKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKarEDLRKLQDESTRLQEACDRAALQLS 951
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE--EELEELQEELERLEEALEELREELE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   952 RAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQ----------------SELERVTYELERA-HAAQTKASASVE 1014
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKallknqsglsgilgvlSELISVDEGYEAAiEAALGGRLQAVV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1015 AAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENE-------------------------------- 1062
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGflgvakdlvkfdpklrkalsyllggvlvvddl 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1063 ----RLREKLDKTLM------ELETIRGKSQYESESFE----KYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKML 1128
Cdd:TIGR02168  632 dnalELAKKLRPGYRivtldgDLVRPGGVITGGSAKTNssilERRREIEELEEKIEELEEKIAELEKALAELRKELEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1129 ANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSpgdpvrastssssALSAGERQEIDRLRDRLEKALQSRD 1208
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS-------------KELTELEAEIEELEERLEEAEEELA 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1209 ATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRsggagaaphpQLEKHVQ 1288
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----------DLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1289 KLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQ 1368
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928


                   ....*..
gi 116007678  1369 TLQQKLQ 1375
Cdd:TIGR02168  929 LRLEGLE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 583-1329 2.24e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.96  E-value: 2.24e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   583 SQELDRAQERADKA------SAELRRTQAELRVTQsdAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQEL 656
Cdd:TIGR02169  197 RQQLERLRREREKAeryqalLKEKREYEGYELLKE--KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   657 EKAQSGVSRIHADRDRAF-SEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEK 735
Cdd:TIGR02169  275 EELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   736 LTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERsesaqtllmkaar 815
Cdd:TIGR02169  355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE------------- 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   816 dREAMQTDLEVLKERyekshaiQQKLQMERDDAVTEVEILKEKLdkalyasQKLIDEKDTSNKEFEKMLEKYDRAQNEIY 895
Cdd:TIGR02169  422 -LADLNAAIAGIEAK-------INELEEEKEDKALEIKKQEWKL-------EQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   896 RLQSRCDTAEAdRARLEVEAERSGLAASKARED--------LRKLQDESTRLQEACDRAA---LQL------SRAKECED 958
Cdd:TIGR02169  487 KLQRELAEAEA-QARASEERVRGGRAVEEVLKAsiqgvhgtVAQLGSVGERYATAIEVAAgnrLNNvvveddAVAKEAIE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   959 NARSElEHSRDRFDKLqTDIRRAQGEKEHFQSE------LERVTYELERAHA-----AQTKASASVEAAKEEAAHY-AVE 1026
Cdd:TIGR02169  566 LLKRR-KAGRATFLPL-NKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAfkyvfGDTLVVEDIEAARRLMGKYrMVT 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1027 LEKmrDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGK-SQYESESFEKYKdkyekiemEVQN 1105
Cdd:TIGR02169  644 LEG--ELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSElRRIENRLDELSQ--------ELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1106 MESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSP--GDPVRASTSSSS 1183
Cdd:TIGR02169  714 ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEalNDLEARLSHSRI 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1184 ALSAGERQEIDRLRDRLEKALQSRDAT----ELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKA 1259
Cdd:TIGR02169  794 PEIQAELSKLEEEVSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL 873

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1260 EAEREALRqanrsggagaAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAEL 1329
Cdd:TIGR02169  874 EAALRDLE----------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 198-945 3.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.17  E-value: 3.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   198 LRMRQPNLEMQ----QQMEAIYAENDHLQREISILRetIKDLECRVETQKQTLIA---RDESIKKLLEMLQAKGMGKEEE 270
Cdd:TIGR02168  198 LERQLKSLERQaekaERYKELKAELRELELALLVLR--LEELREELEELQEELKEaeeELEELTAELQELEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   271 RQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTL-------EEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEE 343
Cdd:TIGR02168  276 VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLerqleelEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   344 MRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKdhmdikdRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQA 423
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLE-------LQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   424 hhSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEK---QEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERE 500
Cdd:TIGR02168  429 --KLEEAELKELQAELEELEEELEELQEELERLEEALeelREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   501 RL-EIKLEASQ--------SELGKSKAELEKATCEMGRSSA------DWESTKQRIARLE---------LENERLKHDLE 556
Cdd:TIGR02168  507 GVkALLKNQSGlsgilgvlSELISVDEGYEAAIEAALGGRLqavvveNLNAAKKAIAFLKqnelgrvtfLPLDSIKGTEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   557 RSQNVQKLMFETGKISTTFGRTTMTTS---------------QELDRAQERADKASAELR-------------------- 601
Cdd:TIGR02168  587 QGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsa 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   602 RTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIK 681
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   682 EEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKER 761
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   762 ETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKshaiqqkl 841
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE-------- 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   842 qmerddavteveiLKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCdtaeadRARLEVEAERSGLA 921
Cdd:TIGR02168  899 -------------LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEAEAL 959

                          810       820
                   ....*....|....*....|....
gi 116007678   922 ASKAREDLRKLQDESTRLQEACDR 945
Cdd:TIGR02168  960 ENKIEDDEEEARRRLKRLENKIKE 983
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 184-757 5.88e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 5.88e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  184 KQAMLVRQLEEELRLRMRQPNL----EMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEM 259
Cdd:COG1196   210 EKAERYRELKEELKELEAELLLlklrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  260 LQAKGMGKEEERQmfqqMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQT 339
Cdd:COG1196   290 EYELLAELARLEQ----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  340 DVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLS 419
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  420 AMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTER 499
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  500 ERLEIKLEASQSELgkskAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTT 579
Cdd:COG1196   526 VAVLIGVEAAYEAA----LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  580 MTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKA 659
Cdd:COG1196   602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  660 QSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYD 739
Cdd:COG1196   682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                         570
                  ....*....|....*...
gi 116007678  740 YDNLQSQLDKALGQAARM 757
Cdd:COG1196   762 LEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 290-1103 5.80e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 5.80e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   290 LEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQEr 369
Cdd:TIGR02169  216 LLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   370 nrltseltelkdhmdikdrKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQL 449
Cdd:TIGR02169  295 -------------------KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKL 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   450 RDQRDraehEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLeikleasQSELGKSKAELEKATCEMGR 529
Cdd:TIGR02169  356 TEEYA----ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINEL-------KRELDRLQEELQRLSEELAD 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   530 SSADWESTKQRIArlELENERLKHDLERSQNVQKLMfETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRV 609
Cdd:TIGR02169  425 LNAAIAGIEAKIN--ELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   610 TQSDAERAREEAAALQEKLEKSQGEVYRL-------KAKLENAQG--------EQESLRQEL-----EKAQSGVSRIHAD 669
Cdd:TIGR02169  502 SEERVRGGRAVEEVLKASIQGVHGTVAQLgsvgeryATAIEVAAGnrlnnvvvEDDAVAKEAiellkRRKAGRATFLPLN 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   670 RDRAF-SEVEKIKE-----------EMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQ------DKLDKA------CTE 725
Cdd:TIGR02169  582 KMRDErRDLSILSEdgvigfavdlvEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRmvtlegELFEKSgamtggSRA 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   726 NRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSES 805
Cdd:TIGR02169  662 PRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   806 AQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAvteveilkekldkalyasqklidEKDTSNKEFEKMLE 885
Cdd:TIGR02169  742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL-----------------------EARLSHSRIPEIQA 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   886 KYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELE 965
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   966 HSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYavELEKMRDRYEKSQV-ELRKL 1044
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI--EDPKGEDEEIPEEElSLEDV 956

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 116007678  1045 QDT-DTFGRETRRLKEENERLREKLD---KTLMELETIRGKSQYESESFEKYKDKYEKIEMEV 1103
Cdd:TIGR02169  957 QAElQRVEEEIRALEPVNMLAIQEYEevlKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
761-1266 2.36e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 68.91  E-value: 2.36e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  761 RETLSLDTDRIREKLEKTQV-QLGRIQKERDQFSDELETLKERSESAQTLLMKAA---RDREAMQTDLEVLKERYEKSHA 836
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDLHeRLNGLESELAELDEEIERYEEQREQARETRDEADevlEEHEERREELETLEAEIEDLRE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  837 IQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAE 916
Cdd:PRK02224  266 TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  917 RSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERV- 995
Cdd:PRK02224  346 SLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELr 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  996 ------TYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDtdtfgrETRRLKEENERLREKLD 1069
Cdd:PRK02224  426 ereaelEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEA------ELEDLEEEVEEVEERLE 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1070 ktlmeletiRGKSQYESES-FEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKA 1148
Cdd:PRK02224  500 ---------RAEDLVEAEDrIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEA 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1149 RD-------KHEKLLKEVDRLRLQQSSVSP----GDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRL 1217
Cdd:PRK02224  571 REevaelnsKLAELKERIESLERIRTLLAAiadaEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEE 650

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 116007678 1218 AKE-LEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREAL 1266
Cdd:PRK02224  651 AREdKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERR 700
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 653-1379 2.42e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 2.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   653 RQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQnEVDHLQDKLDKacTENRRLVLE 732
Cdd:TIGR02169  155 RRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKRE--YEGYELLKE 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   733 KEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLE--------KTQVQLGRIQKERDQFSDELETLKERSE 804
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEelnkkikdLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   805 SAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKML 884
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   885 EKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSEL 964
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   965 EhsrdrfdKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKE--EAAHYAV-ELEKMRDRYEKS---- 1037
Cdd:TIGR02169  472 Y-------DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAsiQGVHGTVaQLGSVGERYATAieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1038 ---QVELRKLQDTDTFGRETRRLKEENERlreklDKTLMELETIRGKSQYESESFEK-----------YKDKYEKI---- 1099
Cdd:TIGR02169  545 agnRLNNVVVEDDAVAKEAIELLKRRKAG-----RATFLPLNKMRDERRDLSILSEDgvigfavdlveFDPKYEPAfkyv 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1100 ---EMEVQNMES-KLHETSLQLELSKGEV----AKMLANQEKQRSELERAHIEREKA---RDKHEKLLKEVDRLRLQQSS 1168
Cdd:TIGR02169  620 fgdTLVVEDIEAaRRLMGKYRMVTLEGELfeksGAMTGGSRAPRGGILFSRSEPAELqrlRERLEGLKRELSSLQSELRR 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1169 VspgdpvrastssssalsageRQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAE 1248
Cdd:TIGR02169  700 I--------------------ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1249 LGRLHDRLEKAEAEREALRQANRSGGAGAAPH--PQLEKHVQKLESDVKQLAM----------EREQLVLQLEKSQEILM 1316
Cdd:TIGR02169  760 LKELEARIEELEEDLHKLEEALNDLEARLSHSriPEIQAELSKLEEEVSRIEArlreieqklnRLTLEKEYLEKEIQELQ 839

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678  1317 NFQKELQNAEAELQKTREE-NRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESER 1379
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENlNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 155-830 1.75e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 1.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   155 KKERALRKEESAKYSL---------INDQLKLLSTENQK----QAMLVRQLEEELRLRMRQPNlEMQQQMEAIYAENDHL 221
Cdd:TIGR02169  171 KKEKALEELEEVEENIerldliideKRQQLERLRREREKaeryQALLKEKREYEGYELLKEKE-ALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   222 QREISILRETIKDLECRVETQKQTLIARDESIKKLLE----MLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQ 297
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   298 EILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEknrliekktqgtlqTVQERNRLTSELT 377
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE--------------TRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   378 ELKdhmdikdRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAE 457
Cdd:TIGR02169  396 KLK-------REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   458 hekQEERDLHErEVADYKIKLRAAESEVEKLQTR---LERAVTERERLEIKLEASQ-------SELGKSKAELEKAtCEM 527
Cdd:TIGR02169  469 ---QELYDLKE-EYDRVEKELSKLQRELAEAEAQaraSEERVRGGRAVEEVLKASIqgvhgtvAQLGSVGERYATA-IEV 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   528 GRSSA------DWESTKQ--------------------RIARLELENERLKHDL------------ERSQNVQKLMF--- 566
Cdd:TIGR02169  544 AAGNRlnnvvvEDDAVAKeaiellkrrkagratflplnKMRDERRDLSILSEDGvigfavdlvefdPKYEPAFKYVFgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   567 ------ETGK---------------------------ISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSD 613
Cdd:TIGR02169  624 lvvediEAARrlmgkyrmvtlegelfeksgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   614 AERAREEAAALQEKLEKSQGEVYRL-------KAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMER 686
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLeqeeeklKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   687 TQATLGKSQLQheKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSL 766
Cdd:TIGR02169  784 LEARLSHSRIP--EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNG 861

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116007678   767 DTDRIREKLEKTQV-------QLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKER 830
Cdd:TIGR02169  862 KKEELEEELEELEAalrdlesRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
431-976 1.64e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 63.14  E-value: 1.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  431 ALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHErEVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQ 510
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLR 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  511 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKlmfetgkistTFGRTTMTTSQELDRAQ 590
Cdd:PRK02224  286 ERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ----------AHNEEAESLREDADDLE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  591 ERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADR 670
Cdd:PRK02224  356 ERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATL 435

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  671 DRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLtydydnlqSQLDKA 750
Cdd:PRK02224  436 RTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERA--------EDLVEA 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  751 LGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKER 830
Cdd:PRK02224  508 EDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKER 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  831 YEKSHAIQQKLQmERDDAVTEVEILKEKLDKalyasqklIDEKDTSNKefEKMLEKYDRAQNEIYRLQ-SRCDTAEADRA 909
Cdd:PRK02224  588 IESLERIRTLLA-AIADAEDEIERLREKREA--------LAELNDERR--ERLAEKRERKRELEAEFDeARIEEAREDKE 656

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116007678  910 RLEVEAErsglaasKAREDLRKLQDESTRLQEACDRAALQLSRAKECednaRSELEHSRDRFDKLQT 976
Cdd:PRK02224  657 RAEEYLE-------QVEEKLDELREERDDLQAEIGAVENELEELEEL----RERREALENRVEALEA 712
PTZ00121 PTZ00121
MAEBL; Provisional
 349-1140 3.96e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 3.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  349 EEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIEnlEDLLKEKDNQVDMARARLSAMQAHHSSS 428
Cdd:PTZ00121 1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAE--EARKAEDAKRVEIARKAEDARKAEEARK 1171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  429 EGALTSLEEAIGDKEKQMA-QLRDQRD--RAEHEKQEERDLHEREVADYKIKLRAAE----SEVEKLQTRLERAVTERER 501
Cdd:PTZ00121 1172 AEDAKKAEAARKAEEVRKAeELRKAEDarKAEAARKAEEERKAEEARKAEDAKKAEAvkkaEEAKKDAEEAKKAEEERNN 1251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  502 LEIK------LEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLE---RSQNVQKLMFETGKIS 572
Cdd:PTZ00121 1252 EEIRkfeearMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKA 1331

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  573 TTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESL 652
Cdd:PTZ00121 1332 DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELK 1411

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  653 RQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQlQHEKLQNSLDKAQN--EVDHLQDKLDKA-CTENRRL 729
Cdd:PTZ00121 1412 KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAE-EAKKAEEAKKKAEEakKADEAKKKAEEAkKADEAKK 1490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  730 VLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTl 809
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEA- 1569

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  810 lMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEvEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDR 889
Cdd:PTZ00121 1570 -KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE-EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  890 AQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAalQLSRAKECEDNARSELEHSRD 969
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA--EELKKKEAEEKKKAEELKKAE 1725

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  970 RFDKLQTDIRRAQGEKEHFQSELERVTyELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVEL-RKLQDT- 1047
Cdd:PTZ00121 1726 EENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVdKKIKDIf 1804

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1048 DTFGRETRRLKEEN---ERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEV 1124
Cdd:PTZ00121 1805 DNFANIIEGGKEGNlviNDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEI 1884

                         810
                  ....*....|....*.
gi 116007678 1125 AKMLANQEKQRSELER 1140
Cdd:PTZ00121 1885 EEADEIEKIDKDDIER 1900
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 285-545 8.03e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 8.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   285 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQgtlq 364
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ---- 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   365 tvqERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDllKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEK 444
Cdd:TIGR02169  752 ---EIENVKSELKELEARIEELEEDLHKLEEALNDLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   445 QMAQLRDQRDRAEH---EKQEERDLHEREVADYKIKLRAAESEVEKLQ-------TRLERAVTERERLEIKLEASQSELG 514
Cdd:TIGR02169  827 EKEYLEKEIQELQEqriDLKEQIKSIEKEIENLNGKKEELEEELEELEaalrdleSRLGDLKKERDELEAQLRELERKIE 906

                          250       260       270
                   ....*....|....*....|....*....|.
gi 116007678   515 KSKAELEKATCEMGRSSADWESTKQRIARLE 545
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 963-1711 1.25e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   963 ELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELR 1042
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1043 KLQdtdtfgRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKG 1122
Cdd:TIGR02168  313 NLE------RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1123 EVAKMLANQEKQRSELERAHIE-------REKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIdR 1195
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARlerledrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE-E 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1196 LRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEF---ERMGAELGRLHDRLEkAEAEREALRQANRS 1272
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLknqSGLSGILGVLSELIS-VDEGYEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1273 GGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAE------AELQKTREENRKLRNG---- 1342
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvaKDLVKFDPKLRKALSYllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1343 -HQVPPVAAPPAGPSPAEFQAMqkeIQTLQQKLQeseRALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADK 1421
Cdd:TIGR02168  625 vLVVDDLDNALELAKKLRPGYR---IVTLDGDLV---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1422 AAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVqqaaqqqqsaagaggadpKELEKVRGELQAACTERDRFQ 1501
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE------------------AEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1502 QQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQI 1581
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1582 DNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQL 1661
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 116007678  1662 EACVKELQNTKEEHK-KAATETERLLQLVQMSQEEQNAKEKTIMDLQQALK 1711
Cdd:TIGR02168  921 REKLAQLELRLEGLEvRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEAR 971
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
432-1069 1.27e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 1.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  432 LTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQS 511
Cdd:COG4913   237 LERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEA 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  512 ELGKSKAELEKATCEMgrssadWESTKQRIARLELENERLKHDLERsqnvqklmfetgkisttfgrttmtTSQELDRAQE 591
Cdd:COG4913   317 RLDALREELDELEAQI------RGNGGDRLEQLEREIERLERELEE------------------------RERRRARLEA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  592 RADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKsqgEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHAdrd 671
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRKSNIPA--- 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  672 rafsEVEKIKEEMERtQATLGKSQLQ-----------HEKLQNS------------------LDKAQNEVDHLQ------ 716
Cdd:COG4913   441 ----RLLALRDALAE-ALGLDEAELPfvgelievrpeEERWRGAiervlggfaltllvppehYAAALRWVNRLHlrgrlv 515

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  717 -DKLDKACTENRRLVLEK----EKLTYDYDNLQSQLDKALGQAARMQK--ERETLSLDTDRI-REKLEKTQVQLGRIQKE 788
Cdd:COG4913   516 yERVRTGLPDPERPRLDPdslaGKLDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRHPRAItRAGQVKGNGTRHEKDDR 595

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  789 RDQFS---------DELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQklqmerddaVTEVEILKEKL 859
Cdd:COG4913   596 RRIRSryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE---------YSWDEIDVASA 666

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  860 DKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERsglaASKAREDLRKLQDESTRL 939
Cdd:COG4913   667 EREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ----AEEELDELQDRLEAAEDL 742

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  940 QEACDRAALQLSRAKECEDNARSELehsrdrFDKLQTDIRRAQGEKEHFQSELERVtyeLERAHAAQTKASASVEAAKEE 1019
Cdd:COG4913   743 ARLELRALLEERFAAALGDAVEREL------RENLEERIDALRARLNRAEEELERA---MRAFNREWPAETADLDADLES 813

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....
gi 116007678 1020 AAHYAVELEKMRD----RYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLD 1069
Cdd:COG4913   814 LPEYLALLDRLEEdglpEYEERFKELLNENSIEFVADLLSKLRRAIREIKERID 867
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 219-966 1.59e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 1.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   219 DHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQE 298
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   299 ILAMAAKMKTLEEQHQDyqrhiavlkeslcAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTE 378
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKD-------------LGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   379 LKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEH 458
Cdd:TIGR02169  334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   459 EKQEERDlherEVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTK 538
Cdd:TIGR02169  414 ELQRLSE----ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   539 QRIARLELENERLKHDLERSQNVQKLMFETGK---------ISTTFGRTTMTTSQELDRAQ-------ERADKASAELRR 602
Cdd:TIGR02169  490 RELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlGSVGERYATAIEVAAGNRLNnvvveddAVAKEAIELLKR 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   603 TQA---------ELRVTQSDAERAREEAA--------ALQEKLEKSQGEVYRLKAKLENAQGEQE--------SLRQELE 657
Cdd:TIGR02169  570 RKAgratflplnKMRDERRDLSILSEDGVigfavdlvEFDPKYEPAFKYVFGDTLVVEDIEAARRlmgkyrmvTLEGELF 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   658 KAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLT 737
Cdd:TIGR02169  650 EKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   738 YDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELetLKERSESAQTLLMKAARDR 817
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEIQAELSKLEEEV 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   818 EAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDkalyasqKLIDEKDTSNKEFEKMLEKYDRAQNEIYRL 897
Cdd:TIGR02169  808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIK-------SIEKEIENLNGKKEELEEELEELEAALRDL 880

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116007678   898 QSRCDTAEADRARLEveaersglaaskarEDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH 966
Cdd:TIGR02169  881 ESRLGDLKKERDELE--------------AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 171-711 3.40e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 3.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   171 INDQLKLLSTENQ-KQAMLVRQLEEELRLRMRQPNLEM-----------------QQQMEAIYAE----NDHLQREISIL 228
Cdd:pfam15921  243 VEDQLEALKSESQnKIELLLQQHQDRIEQLISEHEVEItgltekassarsqansiQSQLEIIQEQarnqNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   229 RETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKT 308
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKR 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   309 LEEQHQDYQRHIAVLKESLCAKEEHYNML-----------QTDVEEMRARLEEKNRLIEKKTQGTLQ---TVQERNRLTS 374
Cdd:pfam15921  403 LWDRDTGNSITIDHLRRELDDRNMEVQRLeallkamksecQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   375 ELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARAR--LSAMQAHHSSSEG--------ALTSLEEAIGDKEK 444
Cdd:pfam15921  483 ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdLKLQELQHLKNEGdhlrnvqtECEALKLQMAEKDK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   445 ----------QMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRaaesEVEKLQTRLERAVTErerleikLEASQSELG 514
Cdd:pfam15921  563 vieilrqqieNMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIRE-------LEARVSDLE 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   515 KSKAELEKATCEMGRSSADwestkqriarLELENERLKHDLERSQN-VQKLMFETGKISTTFGRTTMTTSQELDRAQERA 593
Cdd:pfam15921  632 LEKVKLVNAGSERLRAVKD----------IKQERDQLLNEVKTSRNeLNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQL 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   594 DKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLE-------NAQGEQESLRQELEKAQSGVSRI 666
Cdd:pfam15921  702 KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQfleeamtNANKEKHFLKEEKNKLSQELSTV 781

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 116007678   667 HADRDRAFSEVE-------KIKEEMERTQATLGKSQLQHEKLQNSLDKAQNE 711
Cdd:pfam15921  782 ATEKNKMAGELEvlrsqerRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1095-1670 5.02e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 5.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1095 KYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQssvspgDP 1174
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI------AR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1175 VRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHD 1254
Cdd:COG1196   307 LEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1255 RLEKAEAEREALRQANRsggagaaphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTRE 1334
Cdd:COG1196   387 ELLEALRAAAELAAQLE----------ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1335 ENRKLRnghqvppvaaPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASRE--EIEQWRKVIEQE 1412
Cdd:COG1196   457 EEEALL----------ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalLLAGLRGLAGAV 526

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1413 KSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQA 1492
Cdd:COG1196   527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1493 ACTERDRFQQQLELLVTElekskmSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQK 1572
Cdd:COG1196   607 DLREADARYYVLGDTLLG------RTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1573 QLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNK 1652
Cdd:COG1196   681 LEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                         570
                  ....*....|....*...
gi 116007678 1653 KLMDTQRQLeacvKELQN 1670
Cdd:COG1196   761 DLEELEREL----ERLER 774
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
587-1035 6.99e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 6.99e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  587 DRAQERADKASAELrrtqAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRI 666
Cdd:PRK02224  230 EQARETRDEADEVL----EEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLD 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  667 HADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQ 746
Cdd:PRK02224  306 DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREE 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  747 LDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLL---------------- 810
Cdd:PRK02224  386 IEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecgqpvegsp 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  811 -MKAARDREAMQTDLEVLKERYEKSHAIQQKlQMERDDAVTEVEILKEKLDKALYASQKLIDEK-DTSNKEFEKMLEKYD 888
Cdd:PRK02224  466 hVETIEEDRERVEELEAELEDLEEEVEEVEE-RLERAEDLVEAEDRIERLEERREDLEELIAERrETIEEKRERAEELRE 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  889 RAQN-----EIYRLQSRCDTAEADRARLEVEAERSGLAASKAR----EDLRKLQDESTRLQEACDRAALQLSRAKECEDN 959
Cdd:PRK02224  545 RAAEleaeaEEKREAAAEAEEEAEEAREEVAELNSKLAELKERieslERIRTLLAAIADAEDEIERLREKREALAELNDE 624

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  960 ARSELEHSRDRFDKLQTD-----IRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAhyavELEKMRDRY 1034
Cdd:PRK02224  625 RRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE----ELEELRERR 700


                  .
gi 116007678 1035 E 1035
Cdd:PRK02224  701 E 701
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 167-940 9.14e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.44  E-value: 9.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   167 KYSLINDQLKLLSTENQKQAMLvrqleeELRLRMRQPNLEMQQQMEAIYAEndhLQREISILRETIKDLECRVETQKQTL 246
Cdd:pfam15921  109 RQSVIDLQTKLQEMQMERDAMA------DIRRRESQSQEDLRNQLQNTVHE---LEAAKCLKEDMLEDSNTQIEQLRKMM 179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   247 IARDESIKKLLEML----QAKGMGKEEERQM----FQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQD--- 315
Cdd:pfam15921  180 LSHEGVLQEIRSILvdfeEASGKKIYEHDSMstmhFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNkie 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   316 --YQRHIAVLKESLCAKEEHYNMLQTDVEEMRARleeknrliEKKTQGTLQTVQE--RNRLTSELTELKDHMDIKDRKIS 391
Cdd:pfam15921  260 llLQQHQDRIEQLISEHEVEITGLTEKASSARSQ--------ANSIQSQLEIIQEqaRNQNSMYMRQLSDLESTVSQLRS 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   392 VLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIgdkEKQMAQLRDQRDRAEHEKQEERDLHEREV 471
Cdd:pfam15921  332 ELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQL---QKLLADLHKREKELSLEKEQNKRLWDRDT 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   472 ADykiklraaESEVEKLQTRLERAVTERERLEIKLEASQSElgkSKAELEKATCEMGRSSADWESTKQRIARLELENERL 551
Cdd:pfam15921  409 GN--------SITIDHLRRELDDRNMEVQRLEALLKAMKSE---CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEML 477

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   552 KHDLERsQNVQKLMFETgkiSTTFGRTTMTTSQELDRAQERADKASAELRrTQAELRVTQSDAERAReeaaalQEKLEKS 631
Cdd:pfam15921  478 RKVVEE-LTAKKMTLES---SERTVSDLTASLQEKERAIEATNAEITKLR-SRVDLKLQELQHLKNE------GDHLRNV 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   632 QGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRihADRDRAFSEVEKIKEEMErtqatLGKSQLQHEKLQNSLDKAQNE 711
Cdd:pfam15921  547 QTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ--HGRTAGAMQVEKAQLEKE-----INDRRLELQEFKILKDKKDAK 619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   712 VDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTD----RIREKLEKTQVQLGRIQK 787
Cdd:pfam15921  620 IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrNFRNKSEEMETTTNKLKM 699

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   788 ERDQFSDELEtlkersESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIqqklqmerDDAVTEVEILKEKLDKALYASQ 867
Cdd:pfam15921  700 QLKSAQSELE------QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI--------DALQSKIQFLEEAMTNANKEKH 765

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 116007678   868 KLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQ 940
Cdd:pfam15921  766 FLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
669-1270 9.50e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 9.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  669 DRDRAFSEVEKIKEEMErtqatlgksqlQHEKLQNSLDKAQNEVDHLQ------DKLDKACTENRRLVLEKEKLTYD--- 739
Cdd:COG4913   219 EEPDTFEAADALVEHFD-----------DLERAHEALEDAREQIELLEpirelaERYAAARERLAELEYLRAALRLWfaq 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  740 --YDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLgriqkeRDQFSDELETLKERSESAQTLLMKAARDR 817
Cdd:COG4913   288 rrLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQI------RGNGGDRLEQLEREIERLERELEERERRR 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  818 EAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKlidekdtsnkEFEKMLEKYDRAQNEIYRL 897
Cdd:COG4913   362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEA----------ALRDLRRELRELEAEIASL 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  898 QSRCDT--AEADRARLEVEAersglAASKAREDLR------KLQDESTRLQEACDRA----ALQLSRAKECEDNARSELE 965
Cdd:COG4913   432 ERRKSNipARLLALRDALAE-----ALGLDEAELPfvgeliEVRPEEERWRGAIERVlggfALTLLVPPEHYAAALRWVN 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  966 HSRDR----FDKLQTDIRRAQGEKEHFQSELERVTYELERAHA------AQTKASASVEAAKE-EAAHYAVELEKM---- 1030
Cdd:COG4913   507 RLHLRgrlvYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwleaelGRRFDYVCVDSPEElRRHPRAITRAGQvkgn 586

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1031 RDRYEKsqvELRKLQDTD-TFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIE--------- 1100
Cdd:COG4913   587 GTRHEK---DDRRRIRSRyVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidv 663

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1101 MEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTS 1180
Cdd:COG4913   664 ASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLA 743

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1181 SSSALSAGERQ----EIDRLRDRLEKALQSR-DATELEAGRLAKELEKAQM-HLAKQQENTESTRIEFERMG---AELGR 1251
Cdd:COG4913   744 RLELRALLEERfaaaLGDAVERELRENLEERiDALRARLNRAEEELERAMRaFNREWPAETADLDADLESLPeylALLDR 823

                         650       660
                  ....*....|....*....|.
gi 116007678 1252 L-HDRLEKAEAE-REALRQAN 1270
Cdd:COG4913   824 LeEDGLPEYEERfKELLNENS 844
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 215-983 1.99e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.28  E-value: 1.99e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   215 YAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQR 294
Cdd:pfam15921   70 YPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQN 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   295 RDQEILAmAAKMKtlEEQHQDYQRHIAVLKESLCAKEEHYNMLQT---DVEEMRARleeknRLIEKKTQGTLQTVQERNR 371
Cdd:pfam15921  150 TVHELEA-AKCLK--EDMLEDSNTQIEQLRKMMLSHEGVLQEIRSilvDFEEASGK-----KIYEHDSMSTMHFRSLGSA 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   372 LTSELTELkdhmdikDRKISVLQRKI----ENLEDLLKEKDNQVDMArarlsaMQAHHSSSEGALTSLEEAIGDKEKQMA 447
Cdd:pfam15921  222 ISKILREL-------DTEISYLKGRIfpveDQLEALKSESQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKAS 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   448 QLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAvteRERLEIKLEASQSELGKSKAELEKATCEM 527
Cdd:pfam15921  289 SARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREA---KRMYEDKIEELEKQLVLANSELTEARTER 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   528 GRSSADWESTKQRIARL--ELENERLKHDLERSQNVQKLMFETGKisttfgrttmttSQELDRAQERADKASAELRRTQA 605
Cdd:pfam15921  366 DQFSQESGNLDDQLQKLlaDLHKREKELSLEKEQNKRLWDRDTGN------------SITIDHLRRELDDRNMEVQRLEA 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   606 ELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEME 685
Cdd:pfam15921  434 LLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIE 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   686 RTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDkLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAAR----MQKER 761
Cdd:pfam15921  514 ATNAEITKLRSRVDLKLQELQHLKNEGDHLRN-VQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRtagaMQVEK 592

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   762 ETLSLDTDRIREKLEKTQV----QLGRIQKERDQFSD-ELETLKERSESAQTLL----MKAARDR------------EAM 820
Cdd:pfam15921  593 AQLEKEINDRRLELQEFKIlkdkKDAKIRELEARVSDlELEKVKLVNAGSERLRavkdIKQERDQllnevktsrnelNSL 672

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   821 QTDLEVLKERY----EKSHAIQQKLQMERDDAVTEVEILKEKLD----------KALYASQKLIDEK----DTSNKEFEK 882
Cdd:pfam15921  673 SEDYEVLKRNFrnksEEMETTTNKLKMQLKSAQSELEQTRNTLKsmegsdghamKVAMGMQKQITAKrgqiDALQSKIQF 752

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   883 MLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSrakECEDNARS 962
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFA---ECQDIIQR 829

                          810       820
                   ....*....|....*....|.
gi 116007678   963 ELEHSRDRFDKLQTDIRRAQG 983
Cdd:pfam15921  830 QEQESVRLKLQHTLDVKELQG 850
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1031-1611 2.12e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 2.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1031 RDRYEKSQVELRKLQDtdtfgretRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKL 1110
Cdd:COG1196   219 KEELKELEAELLLLKL--------RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1111 HETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVspgDPVRASTSSSSALSAGER 1190
Cdd:COG1196   291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA---EEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1191 QEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRiefERMGAELGRLHDRLEKAEAEREALRQAN 1270
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL---ERLEEELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1271 RSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAA 1350
Cdd:COG1196   445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1351 PPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIeqwrkvIEQEKSRADMADKAAQEMHKRI 1430
Cdd:COG1196   525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF------LPLDKIRARAALAAALARGAIG 598

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1431 QLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTE 1510
Cdd:COG1196   599 AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1511 LEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEvRKQIDNQAKATEG 1590
Cdd:COG1196   679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE-EELLEEEALEELP 757

                         570       580
                  ....*....|....*....|.
gi 116007678 1591 ERKIIDEQRKQIDAKRKDIEE 1611
Cdd:COG1196   758 EPPDLEELERELERLEREIEA 778
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 353-1164 3.25e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   353 RLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGAL 432
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   433 T----SLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA 508
Cdd:pfam02463  249 EqeeiESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   509 SQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKIstTFGRTTMTTSQELDR 588
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK--LKEEELELKSEEEKE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   589 AQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGE---QESLRQELEKAQSGVSR 665
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELElkkSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   666 IHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKA--CTENRRLVLEKEKLTYDYDNL 743
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVaiSTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   744 QSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQK-----ERDQFSDELETLKERSESAQTLLMKAARDRE 818
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKatleaDEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   819 AMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQ 898
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   899 SRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEH-SRDRFDKLQTD 977
Cdd:pfam02463  727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEkLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   978 IRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRL 1057
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1058 KEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSE 1137
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820
                   ....*....|....*....|....*..
gi 116007678  1138 LERAHIEREKARDKHEKLLKEVDRLRL 1164
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKD 993
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
297-863 6.75e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.54  E-value: 6.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  297 QEILAMAAKMKTLEEQHQDYQRHIAvLKESLCAKEEHYNML-----QTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNR 371
Cdd:COG4913   242 EALEDAREQIELLEPIRELAERYAA-ARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELERLEARLDA 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  372 LTSELTELK-DHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIgdkekqmAQLR 450
Cdd:COG4913   321 LREELDELEaQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA-------AALL 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  451 DQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTrleRAVTERERLEIKLEASQSELGKSKAELEKAtCE---M 527
Cdd:COG4913   394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER---RKSNIPARLLALRDALAEALGLDEAELPFV-GElieV 469

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  528 GRSSADWESTKqriarlelenERLKHDLERSQNVqklmfetgkisttfgrttmttsqeldrAQERADKASAELRRTQAEL 607
Cdd:COG4913   470 RPEEERWRGAI----------ERVLGGFALTLLV---------------------------PPEHYAAALRWVNRLHLRG 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  608 RV-------TQSDAERAREEAAALQEKLEKSQGEVYR-LKAKLENAQG-----EQESLRQElEKA--------QSGVSRI 666
Cdd:COG4913   513 RLvyervrtGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRFDyvcvdSPEELRRH-PRAitragqvkGNGTRHE 591

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  667 HADRDRAFS-----------------EVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRL 729
Cdd:COG4913   592 KDDRRRIRSryvlgfdnraklaaleaELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIA 671

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  730 VLEKEKltydydnlqSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTL 809
Cdd:COG4913   672 ELEAEL---------ERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL 742

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 116007678  810 LMKAARDREAMQTDLEVLKERYEKshaIQQKLQMERDDAVTEVEILKEKLDKAL 863
Cdd:COG4913   743 ARLELRALLEERFAAALGDAVERE---LRENLEERIDALRARLNRAEEELERAM 793
PTZ00121 PTZ00121
MAEBL; Provisional
 977-1711 9.08e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 54.38  E-value: 9.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  977 DIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRR 1056
Cdd:PTZ00121 1086 DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARK 1165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1057 LKEENERLREKLDKTLMELETIRgksqyESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRS 1136
Cdd:PTZ00121 1166 AEEARKAEDAKKAEAARKAEEVR-----KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAE 1240

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1137 ELERAHIEREKARDKHEKLLKEVDRLRLQQSSVS----PGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATEL 1212
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAeearKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEA 1320

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1213 EagrlaKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLEs 1292
Cdd:PTZ00121 1321 K-----KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAD- 1394

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1293 DVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEA-----ELQKTREENRKlrnGHQVPPVAAPPAGPSPAEFQAMQKEI 1367
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkkadEAKKKAEEAKK---ADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1368 QTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIE----QEKSRADMADKAaqEMHKRIQLMDQHIKDQHAQ 1443
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKA--EEAKKADEAKKAEEKKKAD 1549

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1444 MQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTELEKSKmsnQEQAK 1523
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK---AEELK 1626

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1524 QLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQID 1603
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1604 AKRKDIEEKekkmaefdvqlrKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETE 1683
Cdd:PTZ00121 1707 LKKKEAEEK------------KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                         730       740
                  ....*....|....*....|....*...
gi 116007678 1684 RLLQLVqMSQEEQNAKEKTIMDLQQALK 1711
Cdd:PTZ00121 1775 KEKEAV-IEEELDEEDEKRRMEVDKKIK 1801
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 292-892 1.39e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   292 IQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEE-KNRLIEKKTQgtlqtvqeRN 370
Cdd:TIGR04523   28 ANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDlNDKLKKNKDK--------IN 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   371 RLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKE--------------KDNQVDMARARLSAMQAHHSSSEGALTSLE 436
Cdd:TIGR04523  100 KLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKEnkknidkflteikkKEKELEKLNNKYNDLKKQKEELENELNLLE 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   437 EAIGDKEKQMAQLRDQRDRAEH------EKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQ 510
Cdd:TIGR04523  180 KEKLNIQKNIDKIKNKLLKLELllsnlkKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   511 SELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKhdlerSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQ 590
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN-----NQKEQDWNKELKSELKNQEKKLEEIQNQISQNN 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   591 ERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADR 670
Cdd:TIGR04523  335 KIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   671 DRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKA 750
Cdd:TIGR04523  415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   751 LGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTD--LEVLK 828
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNkeIEELK 574

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678   829 ERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQN 892
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKS 638
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
393-941 1.65e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 1.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  393 LQRKIENLEDLLKEKDNQVDMARARLSAMQ---AHHSSSEGALTSLEEAIGDKekqmaqlrdQRDRAEHEKqeERDLHER 469
Cdd:PRK02224  211 LESELAELDEEIERYEEQREQARETRDEADevlEEHEERREELETLEAEIEDL---------RETIAETER--EREELAE 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  470 EVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENE 549
Cdd:PRK02224  280 EVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  550 RLKhdlERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELrvtqsdaerareeaAALQEKLE 629
Cdd:PRK02224  360 ELR---EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFL--------------EELREERD 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  630 KSQGEVYRLKAKLENAQGEQESLRQELE-----------KAQSGVSRIHADRDRafseVEKIKEEMERTQATLGKSQLQH 698
Cdd:PRK02224  423 ELREREAELEATLRTARERVEEAEALLEagkcpecgqpvEGSPHVETIEEDRER----VEELEAELEDLEEEVEEVEERL 498

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  699 EKLQnSLDKAQNEVDHLQDKLDKActeNRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKEREtlslDTDRIREKLEKT 778
Cdd:PRK02224  499 ERAE-DLVEAEDRIERLEERREDL---EELIAERRETIEEKRERAEELRERAAELEAEAEEKRE----AAAEAEEEAEEA 570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  779 QVQLGRIQKERDQFSDELETLkERSESAQTLLMKAARDREAMQTDLEVLKERYEKShaiQQKLQMERDdavtEVEILKEK 858
Cdd:PRK02224  571 REEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREALAELNDER---RERLAEKRE----RKRELEAE 642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  859 LDKAlyASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKaREDLRKLQDESTR 938
Cdd:PRK02224  643 FDEA--RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENR-VEALEALYDEAEE 719


                  ...
gi 116007678  939 LQE 941
Cdd:PRK02224  720 LES 722
PTZ00121 PTZ00121
MAEBL; Provisional
 155-889 2.43e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.84  E-value: 2.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  155 KKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELRLRmrqpnlemqqqmEAIYAENDHLQREISILRETIKD 234
Cdd:PTZ00121 1171 KAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAE------------EARKAEDAKKAEAVKKAEEAKKD 1238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  235 LEcrvETQKQTLIARDESIKKLLEMLQAKGMGK------EEERQMFQQMQAMAQKQLDEFR-LEIQRRDQEILAMAAKMK 307
Cdd:PTZ00121 1239 AE---EAKKAEEERNNEEIRKFEEARMAHFARRqaaikaEEARKADELKKAEEKKKADEAKkAEEKKKADEAKKKAEEAK 1315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  308 TLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRltseLTELKDHMDIKd 387
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK----ADAAKKKAEEK- 1390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  388 RKISVLQRKIENLEdllKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLH 467
Cdd:PTZ00121 1391 KKADEAKKKAEEDK---KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  468 EREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELE 547
Cdd:PTZ00121 1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  548 NERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEK 627
Cdd:PTZ00121 1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  628 LEKSQGEVYRLKAKLENAQGEQESLRQELE--KAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 705
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEenKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  706 DKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREklEKTQVQLGRI 785
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRK--EKEAVIEEEL 1785

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  786 QKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLD----- 860
Cdd:PTZ00121 1786 DEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENgedgn 1865

                         730       740       750
                  ....*....|....*....|....*....|
gi 116007678  861 -KALYASQKLIDEKDTSNKEFEKMLEKYDR 889
Cdd:PTZ00121 1866 kEADFNKEKDLKEDDEEEIEEADEIEKIDK 1895
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 426-1169 2.77e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.36  E-value: 2.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   426 SSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIK 505
Cdd:TIGR00606  227 TSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   506 LEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNvQKLMFETGKISTTFGRTTMTTSQE 585
Cdd:TIGR00606  307 YHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQE-HIRARDSLIQSLATRLELDGFERG 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   586 LDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRL-------KAKLENAQGEQESLRQELEK 658
Cdd:TIGR00606  386 PFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLgrtielkKEILEKKQEELKFVIKELQQ 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   659 AQSGVSRI-HADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRR-LVLEKEKL 736
Cdd:TIGR00606  466 LEGSSDRIlELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQmEMLTKDKM 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   737 TYD---YDNLQSQLDKALGQAA------RMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQ 807
Cdd:TIGR00606  546 DKDeqiRKIKSRHSDELTSLLGyfpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   808 TLLMKAArDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKY 887
Cdd:TIGR00606  626 DKLFDVC-GSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   888 DRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHS 967
Cdd:TIGR00606  705 RLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESA 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   968 RDrfdkLQTDIrraqGEKEHFQSELErvtyELERAHAAQtkasasveAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDT 1047
Cdd:TIGR00606  785 KV----CLTDV----TIMERFQMELK----DVERKIAQQ--------AAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSK 844

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1048 dtfGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKM 1127
Cdd:TIGR00606  845 ---IELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKD 921

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 116007678  1128 lanQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSV 1169
Cdd:TIGR00606  922 ---QQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDI 960
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
749-1344 3.09e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 3.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  749 KALGQAARMQKERETLsldtDRIREKLEKTQVQLGRIQKERDQFsDELETLKERSESAQTLlmKAARDREAMQTDLEVLK 828
Cdd:COG4913   222 DTFEAADALVEHFDDL----ERAHEALEDAREQIELLEPIRELA-ERYAAARERLAELEYL--RAALRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  829 ERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKAlyasQKLIDEKDTSNKEfekmlekydRAQNEIYRLQSRCDTAEADR 908
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDEL----EAQIRGNGGDRLE---------QLEREIERLERELEERERRR 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  909 ARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRaalQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHF 988
Cdd:COG4913   362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE---ELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI 438

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  989 QSELERVTYELERAhaaqtkasasvEAAKEEAAHYAVELEKMRDRYEKSQ--VE-------LRKLQDTDTFGRETRRLKE 1059
Cdd:COG4913   439 PARLLALRDALAEA-----------LGLDEAELPFVGELIEVRPEEERWRgaIErvlggfaLTLLVPPEHYAAALRWVNR 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1060 ENERLR---EKLDKTLMELETIR-------GKSQYESESFEKYkdkyekIEMEVQNM----------ESKLHETSLQLE- 1118
Cdd:COG4913   508 LHLRGRlvyERVRTGLPDPERPRldpdslaGKLDFKPHPFRAW------LEAELGRRfdyvcvdspeELRRHPRAITRAg 581

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1119 LSKG---------------------EVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSpgdpvra 1177
Cdd:COG4913   582 QVKGngtrhekddrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLA------- 654

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1178 STSSSSALSAGERQEIDRLRDRLEKALQSRDateleagrlakELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLE 1257
Cdd:COG4913   655 EYSWDEIDVASAEREIAELEAELERLDASSD-----------DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE 723

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1258 KAEAEREALRQANRSGGAGAAPHPQLEkhvqkLESDVKQLAMEreqlvlqlEKSQEILMNFQKELQNAEAELQKTREENR 1337
Cdd:COG4913   724 QAEEELDELQDRLEAAEDLARLELRAL-----LEERFAAALGD--------AVERELRENLEERIDALRARLNRAEEELE 790


                  ....*..
gi 116007678 1338 KLRNGHQ 1344
Cdd:COG4913   791 RAMRAFN 797
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
206-699 3.65e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 3.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  206 EMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLL---EMLQAKGMGKEEERQMFQQMQAMAQ 282
Cdd:PRK02224  248 ERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLaeaGLDDADAEAVEARREELEDRDEELR 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  283 KQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEknrlIEKKTQGT 362
Cdd:PRK02224  328 DRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEE----LRERFGDA 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  363 lqtvqernrlTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDK 442
Cdd:PRK02224  404 ----------PVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEED 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  443 EKQMAQLRDQRDRAEHEKQEERDLHEREVAdykikLRAAESEVEKLQTRLERAV----TERERLEIKLEASQsELGKSKA 518
Cdd:PRK02224  474 RERVEELEAELEDLEEEVEEVEERLERAED-----LVEAEDRIERLEERREDLEeliaERRETIEEKRERAE-ELRERAA 547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  519 ELEkATCEMGRSSAD-----WESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERA 593
Cdd:PRK02224  548 ELE-AEAEEKREAAAeaeeeAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERR 626

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  594 DKAsAELRRTQAELRVTQSDaerareeaaalqEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIhadrDRA 673
Cdd:PRK02224  627 ERL-AEKRERKRELEAEFDE------------ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAV----ENE 689

                         490       500
                  ....*....|....*....|....*.
gi 116007678  674 FSEVEKIKEEMERTQATLGKSQLQHE 699
Cdd:PRK02224  690 LEELEELRERREALENRVEALEALYD 715
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 532-1168 4.56e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.76  E-value: 4.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   532 ADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQEL-DRAQERADKASAELRRTQAELRVT 610
Cdd:pfam12128  248 QEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKrDELNGELSAADAAVAKDRSELEAL 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   611 QSD----AERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVS-RIHADRDRAFSEVEKIKEEME 685
Cdd:pfam12128  328 EDQhgafLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKeQNNRDIAGIKDKLAKIREARD 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   686 RTQATL-GKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRL---VLEKEKLTYDYDNLQSQLDKALGQAARMQKER 761
Cdd:pfam12128  408 RQLAVAeDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRlnqATATPELLLQLENFDERIERAREEQEAANAEV 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   762 ETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKER-SESAQTLLmkaardrEAMQTDLEVLKERYEKSHAIQQK 840
Cdd:pfam12128  488 ERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlFPQAGTLL-------HFLRKEAPDWEQSIGKVISPELL 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   841 LQMERDDAVTEVEILKE------KLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVE 914
Cdd:pfam12128  561 HRTDLDPEVWDGSVGGElnlygvKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASRE 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   915 AERSGLAASKAREDLRKLQDESTRLQEACDRAalqLSRAKECEDNARSELEHSRDRFDKLQtdirraQGEKEHFQSELer 994
Cdd:pfam12128  641 ETFARTALKNARLDLRRLFDEKQSEKDKKNKA---LAERKDSANERLNSLEAQLKQLDKKH------QAWLEEQKEQK-- 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   995 vtyeLERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRET-----RRLKEENERLREKLD 1069
Cdd:pfam12128  710 ----REARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVdpdviAKLKREIRTLERKIE 785

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1070 KTLMELETIRGKSQYESESFEKYKDKYekiEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKAR 1149
Cdd:pfam12128  786 RIAVRRQEVLRYFDWYQETWLQRRPRL---ATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENL 862

                          650
                   ....*....|....*....
gi 116007678  1150 DKHEKLLKEVDRLRLQQSS 1168
Cdd:pfam12128  863 RGLRCEMSKLATLKEDANS 881
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 757-1652 6.09e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 6.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   757 MQKERETLSLDTD----RIREKLEKTQVQLGRIQKERDQFSDELETLKERSESaqTLLMKAARDREAMQTDLEVLKERYE 832
Cdd:pfam02463  149 MMKPERRLEIEEEaagsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELK--LKEQAKKALEYYQLKEKLELEEEYL 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   833 KSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLE 912
Cdd:pfam02463  227 LYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLE 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   913 VEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSEL 992
Cdd:pfam02463  307 RRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERL 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   993 ERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTdtfgretrrlKEENERLREKLDKTL 1072
Cdd:pfam02463  387 SSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIEL----------KQGKLTEEKEELEKQ 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1073 MELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKH 1152
Cdd:pfam02463  457 ELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1153 EKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKA-LQSRDATELEAGRLAKELEKAQMHLAKQ 1231
Cdd:pfam02463  537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLkLPLKSIAVLEIDPILNLAQLDKATLEAD 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1232 QENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLesDVKQLAMEREQLVLQLEKS 1311
Cdd:pfam02463  617 EDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL--LEIQELQEKAESELAKEEI 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1312 QEILMNFQKELQNAEAELQKTREENRKLRNGhqvppVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQA 1391
Cdd:pfam02463  695 LRRQLEIKKKEQREKEELKKLKLEAEELLAD-----RVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1392 AAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQS 1471
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1472 aagaggadpKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQ 1551
Cdd:pfam02463  850 ---------KLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIE 920

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1552 AASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMD 1631
Cdd:pfam02463  921 ERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000

                          890       900
                   ....*....|....*....|.
gi 116007678  1632 QLEKSLQTQGGGAAAAGELNK 1652
Cdd:pfam02463 1001 EEEKKKLIRAIIEETCQRLKE 1021
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
206-685 7.38e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 7.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  206 EMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLiARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQL 285
Cdd:PRK03918  197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELK-EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEI 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  286 DEFRlEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKK--TQGTL 363
Cdd:PRK03918  276 EELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLkeLEKRL 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  364 QTVQERNRLTSELTELKDHMD-----IKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEA 438
Cdd:PRK03918  355 EELEERHELYEEAKAKKEELErlkkrLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  439 IG------------DKEKQMAQLRDQRDRAEHEKQE----ERDLHEREVADYKIklRAAESEVEKLQTRLERAVTERERL 502
Cdd:PRK03918  435 KGkcpvcgrelteeHRKELLEEYTAELKRIEKELKEieekERKLRKELRELEKV--LKKESELIKLKELAEQLKELEEKL 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  503 EI----KLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRT 578
Cdd:PRK03918  513 KKynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  579 TMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKL-----ENAQGEQESLR 653
Cdd:PRK03918  593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLELS 672

                         490       500       510
                  ....*....|....*....|....*....|..
gi 116007678  654 QELEKAQSGVSRIHADRDRAFSEVEKIKEEME 685
Cdd:PRK03918  673 RELAGLRAELEELEKRREEIKKTLEKLKEELE 704
PRK01156 PRK01156
chromosome segregation protein; Provisional
 285-833 7.79e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 51.06  E-value: 7.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  285 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIE--KKTQGT 362
Cdd:PRK01156  185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESeiKTAESD 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  363 LQTVQERNRLTSELTElkDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMArarlsamqahhSSSEGALTSLEEAIgdk 442
Cdd:PRK01156  265 LSMELEKNNYYKELEE--RHMKIINDPVYKNRNYINDYFKYKNDIENKKQIL-----------SNIDAEINKYHAII--- 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  443 eKQMAQLRDQRDRAEHEKQEERDL-HER-EVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAEL 520
Cdd:PRK01156  329 -KKLSVLQKDYNDYIKKKSRYDDLnNQIlELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  521 EKATCEMGRSSADWEStkqRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELdraqerADKASAEL 600
Cdd:PRK01156  408 KKELNEINVKLQDISS---KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHI------INHYNEKK 478

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  601 RRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRlkaKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKI 680
Cdd:PRK01156  479 SRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEIN---KSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRY 555

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  681 K----EEMERTQATLGKSQLQHEKLqnSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAAR 756
Cdd:PRK01156  556 KslklEDLDSKRTSWLNALAVISLI--DIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNN 633

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  757 MQKERETLSLDTDRIREKLEKTQVQLGR---IQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEK 833
Cdd:PRK01156  634 KYNEIQENKILIEKLRGKIDNYKKQIAEidsIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINE 713
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
220-803 8.24e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 8.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  220 HLQREISILRETIK---DLECRVETQKQTLIARDESIKKLlemlqakgMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRD 296
Cdd:PRK03918  173 EIKRRIERLEKFIKrteNIEELIKEKEKELEEVLREINEI--------SSELPELREELEKLEKEVKELEELKEEIEELE 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  297 QEILAMAAKMKTLEEQHQDYQRHIAVLKESLcakeehynmlqTDVEEMRARLEEknrlIEKKTQGTLQTVQERNRLTSEL 376
Cdd:PRK03918  245 KELESLEGSKRKLEEKIRELEERIEELKKEI-----------EELEEKVKELKE----LKEKAEEYIKLSEFYEEYLDEL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  377 TELKDHMDIKDRKISVLQRKIENLEdllkEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAigdkEKQMAQLRDQRDRA 456
Cdd:PRK03918  310 REIEKRLSRLEEEINGIEERIKELE----EKEERLEELKKKLKELEKRLEELEERHELYEEA----KAKKEELERLKKRL 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  457 EHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAEL---------EKATCEM 527
Cdd:PRK03918  382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteehrkellEEYTAEL 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  528 GRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAEL 607
Cdd:PRK03918  462 KRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI 541

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  608 RVTQSDAERAREEAAALqEKLEKSQGEVYRLKAKLENAQGEQ-----ESLRQELEKAQSGVSRIHADRDrAFSEVEKIKE 682
Cdd:PRK03918  542 KSLKKELEKLEELKKKL-AELEKKLDELEEELAELLKELEELgfesvEELEERLKELEPFYNEYLELKD-AEKELEREEK 619

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  683 EMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTEN-RRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKER 761
Cdd:PRK03918  620 ELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 116007678  762 ETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERS 803
Cdd:PRK03918  700 KEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERA 741
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
591-1163 8.52e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 8.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  591 ERADKASAELRRtqaELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVsrihadr 670
Cdd:PRK03918  161 ENAYKNLGEVIK---EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV------- 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  671 drafSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLdKACTENRRLVLEKEKLTYDYDNLQSQLDKA 750
Cdd:PRK03918  231 ----KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEI-EELEEKVKELKELKEKAEEYIKLSEFYEEY 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  751 LGQAARMQKERETLSLDTDRIRE---KLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQT----D 823
Cdd:PRK03918  306 LDELREIEKRLSRLEEEINGIEErikELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltglT 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  824 LEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDT--------SNKEFEKMLEKYDRaqnEIY 895
Cdd:PRK03918  386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTA---ELK 462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  896 RLQSRCDTAEADRARLEVEAERSGLAASKAREdLRKLQDESTRLQEAcdRAALQLSRAKECEDNARsELEHSRDRFDKLQ 975
Cdd:PRK03918  463 RIEKELKEIEEKERKLRKELRELEKVLKKESE-LIKLKELAEQLKEL--EEKLKKYNLEELEKKAE-EYEKLKEKLIKLK 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  976 TDIRRAQGEKEHFQsELERVTYELERAHAAQTKASASVEAAKEEAAHYAV--------ELEKMRDRYEKSQVELRKLQDT 1047
Cdd:PRK03918  539 GEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELGFESVeeleerlkELEPFYNEYLELKDAEKELERE 617

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1048 DtfgRETRRLKEENERLREKLDKTLMELETIRGK-----SQYESESFEKYKDKYEKIEMEVQNMESKLHEtslqLELSKG 1122
Cdd:PRK03918  618 E---KELKKLEEELDKAFEELAETEKRLEELRKEleeleKKYSEEEYEELREEYLELSRELAGLRAELEE----LEKRRE 690

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 116007678 1123 EVAKMLANQEKQRSELERAHIEREKArdkhEKLLKEVDRLR 1163
Cdd:PRK03918  691 EIKKTLEKLKEELEEREKAKKELEKL----EKALERVEELR 727
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
395-941 1.07e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  395 RKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADY 474
Cdd:PRK03918  207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  475 KIKLRAAE-SEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMgrssadwESTKQRIARLELENERLKH 553
Cdd:PRK03918  287 ELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-------EELKKKLKELEKRLEELEE 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  554 DLERSQNVQKLMFETGKISTTFGRTTMttsQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQG 633
Cdd:PRK03918  360 RHELYEEAKAKKEELERLKKRLTGLTP---EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKG 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  634 EVYRLKAKLenaqgEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKsqlqhEKLQNSLDKAQNEVD 713
Cdd:PRK03918  437 KCPVCGREL-----TEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-----ESELIKLKELAEQLK 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  714 HLQDKLDKACTEnrrlvlEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIRE---KLEKTQVQLGRIQKERD 790
Cdd:PRK03918  507 ELEEKLKKYNLE------ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAElekKLDELEEELAELLKELE 580

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  791 QFSDE-LETLKERSESAQTLLMKAARDREAMQtDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKAlyasQKL 869
Cdd:PRK03918  581 ELGFEsVEELEERLKELEPFYNEYLELKDAEK-ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL----EKK 655

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678  870 IDEKDTSNK--EFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAErsglAASKAREDLRKLQDESTRLQE 941
Cdd:PRK03918  656 YSEEEYEELreEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE----EREKAKKELEKLEKALERVEE 725
PTZ00121 PTZ00121
MAEBL; Provisional
 151-788 1.17e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  151 SPELKKERALRKEESAKyslindqlkllSTENQKQAMLVRQLEEELRLR-MRQPNLEMQQQMEAIYAENDHLQREISILR 229
Cdd:PTZ00121 1190 AEELRKAEDARKAEAAR-----------KAEEERKAEEARKAEDAKKAEaVKKAEEAKKDAEEAKKAEEERNNEEIRKFE 1258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  230 ETIKDLECRVETQKQTLIARD-ESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKT 308
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA 1338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  309 LEEQHQDyqrHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMdikdR 388
Cdd:PTZ00121 1339 EEAKKAA---EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL----K 1411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  389 KISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHE 468
Cdd:PTZ00121 1412 KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKK 1491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  469 REVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKL--EASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLEL 546
Cdd:PTZ00121 1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaeEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKK 1571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  547 ENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAElrvtqsdaeRAREEAAALQE 626
Cdd:PTZ00121 1572 AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE---------KKKVEQLKKKE 1642

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  627 KLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLD 706
Cdd:PTZ00121 1643 AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK 1722

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  707 KAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSldTDRIREKLEKTQVQLGRIQ 786
Cdd:PTZ00121 1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKRRMEVDKKI 1800


                  ..
gi 116007678  787 KE 788
Cdd:PTZ00121 1801 KD 1802
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 251-889 1.26e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.11  E-value: 1.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   251 ESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAK 330
Cdd:pfam05483   88 EKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARS 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   331 EEHYNMLQTDVEEMRARLEEKNRLIEKktqgtLQTVQERNRLTSELTELKDHMDIKDRkisvlQRKIENLEDLLKEKDNQ 410
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNIEK-----MILAFEELRVQAENARLEMHFKLKED-----HEKIQHLEEEYKKEIND 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   411 VDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQT 490
Cdd:pfam05483  238 KEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEE 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   491 RLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTkqriarLELENERLkhdlERSQNVQKLMfetgk 570
Cdd:pfam05483  318 DLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEEL------LRTEQQRL----EKNEDQLKII----- 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   571 isttfGRTTMTTSQELDRAQERADKASAELRrtqaELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQE 650
Cdd:pfam05483  383 -----TMELQKKSSELEEMTKFKNNKEVELE----ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIH 453

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   651 SLRQELEkaqsgvsrihadrdrafseVEKIKEEMERTQATLGKSQLQHEKLQNSldkaqnevdHLQDKLDKACTENRRLV 730
Cdd:pfam05483  454 DLEIQLT-------------------AIKTSEEHYLKEVEDLKTELEKEKLKNI---------ELTAHCDKLLLENKELT 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   731 LEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLgriQKERDQFSDELETLKERSESAQTLL 810
Cdd:pfam05483  506 QEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEF---IQKGDEVKCKLDKSEENARSIEYEV 582

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116007678   811 MKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDR 889
Cdd:pfam05483  583 LKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQK 661
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 117-797 1.38e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.11  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   117 QNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEEL 196
Cdd:pfam05483  123 QELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEEL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   197 RLRMRQPNLEMQQQMEAIYAENDHLQREisiLRETIKDLECRVETQKQTLIARDESIKK---LLEMLQAKGMGKEEERQM 273
Cdd:pfam05483  203 RVQAENARLEMHFKLKEDHEKIQHLEEE---YKKEINDKEKQVSLLLIQITEKENKMKDltfLLEESRDKANQLEEKTKL 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   274 FQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLkeslcakeehynmlqtdVEEMRARLEEKNR 353
Cdd:pfam05483  280 QDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQL-----------------TEEKEAQMEELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   354 liekktqgtlqtvqERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALT 433
Cdd:pfam05483  343 --------------AKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   434 SLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDL------HEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLE 507
Cdd:pfam05483  409 ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELifllqaREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNI 488

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   508 ASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKlmfetgKISTTFGRTTMTTSQELD 587
Cdd:pfam05483  489 ELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEM------NLRDELESVREEFIQKGD 562

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   588 RAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIH 667
Cdd:pfam05483  563 EVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   668 ADRDrafSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDH---LQDKLDKACTEN-RRLVLEKEKLTYDYDNL 743
Cdd:pfam05483  643 LELA---SAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEavkLQKEIDKRCQHKiAEMVALMEKHKHQYDKI 719

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 116007678   744 QSQLDKALGQAARMQKE----RETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELE 797
Cdd:pfam05483  720 IEERDSELGLYKNKEQEqssaKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 79-503 2.14e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 2.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678    79 LEDELYGRSArqspSAMGGYNTGMGPTSDRAYLGDlqhQNTDLQRELGNLKRELELTNQKLgssmHSIKTfwspELKKER 158
Cdd:TIGR02169  644 LEGELFEKSG----AMTGGSRAPRGGILFSRSEPA---ELQRLRERLEGLKRELSSLQSEL----RRIEN----RLDELS 708

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   159 ALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELRlrmrqpnlEMQQQMEAIYAENDHLQREISILRETIKDLECR 238
Cdd:TIGR02169  709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS--------SLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   239 VETQKQTLiaRDESIKKLLEMLQAkgmgKEEERQmfqqmqaMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQR 318
Cdd:TIGR02169  781 LNDLEARL--SHSRIPEIQAELSK----LEEEVS-------RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE 847

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   319 HIavlkeslcakeehyNMLQTDVEEMRARLEEKNRLIEKKTqgtlqtvQERNRLTSELTELKDHMDIKDRKISVLQRKIE 398
Cdd:TIGR02169  848 QI--------------KSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELERKIE 906

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   399 NLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEaIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKL 478
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          410       420
                   ....*....|....*....|....*
gi 116007678   479 RAAESEVEKLQTRLERAVTERERLE 503
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 156-527 3.59e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 3.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   156 KERALRKEESAKYSLINDQLKLLSTENQKQAMLVRQLEEELRLRMRQPNLEmqqqmeaiyAENDHLQREISILRETIKDL 235
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE---------ERIAQLSKELTELEAEIEEL 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   236 ECRVETQKQTLIARDESIKKLlemlqakgmgkEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQD 315
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEEL-----------EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   316 YQRHIAVLKESLCAKEEhynmlqtDVEEMRARLEEKNRLIEKktqgtlqtvqernrLTSELTELKDHMDIKDRKISVLQR 395
Cdd:TIGR02168  836 TERRLEDLEEQIEELSE-------DIESLAAEIEELEELIEE--------------LESELEALLNERASLEEALALLRS 894

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   396 KIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEeaigdkekqmAQLRDQRDRAEHEKQEERDLHEREVADYK 475
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE----------VRIDNLQERLSEEYSLTLEEAEALENKIE 964

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 116007678   476 IKLRAAESEVEKLQTRLER-------AVTERERLE---IKLEASQSELGKSKAELEKATCEM 527
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKeryDFLTAQKEDLTEAKETLEEAIEEI 1026
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
559-864 4.53e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.97  E-value: 4.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  559 QNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRL 638
Cdd:COG4372     6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  639 KAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDK 718
Cdd:COG4372    86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEE 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  719 LDKactenrrlvLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELET 798
Cdd:COG4372   166 LAA---------LEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALS 236

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678  799 LKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALY 864
Cdd:COG4372   237 ALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLL 302
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 110-859 4.58e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 4.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   110 YLGDLQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLIND----QLKLLSTENQKQ 185
Cdd:pfam02463  231 YLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEeeelKSELLKLERRKV 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   186 AMLVRQLEEELRLRMRQPNLEMQQQ-MEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKG 264
Cdd:pfam02463  311 DDEEKLKESEKEKKKAEKELKKEKEeIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAA 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   265 MGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEM 344
Cdd:pfam02463  391 KLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKS 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   345 RARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKD---------RKISVLQRKIENLEDLLKEKDNQVDMAR 415
Cdd:pfam02463  471 EDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLalikdgvggRIISAHGRLGDLGVAVENYKVAISTAVI 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   416 ARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERA 495
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILK 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   496 VTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQR------IARLELENERLKHDLERSQNVQKLMFETG 569
Cdd:pfam02463  631 DTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELleiqelQEKAESELAKEEILRRQLEIKKKEQREKE 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   570 KISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQ--SDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQG 647
Cdd:pfam02463  711 ELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEekSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   648 EQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENR 727
Cdd:pfam02463  791 EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   728 RLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQ----------------KERDQ 791
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIllkyeeepeellleeaDEKEK 950

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 116007678   792 FSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKL 859
Cdd:pfam02463  951 EENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 290-457 7.61e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.07  E-value: 7.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  290 LEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKT--QGTLQTVQ 367
Cdd:COG1579    10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEeqLGNVRNNK 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  368 ERNRLTSELTELKdhmdikdRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHsssEGALTSLEEAIGDKEKQMA 447
Cdd:COG1579    90 EYEALQKEIESLK-------RRISDLEDEILELMERIEELEEELAELEAELAELEAEL---EEKKAELDEELAELEAELE 159

                         170
                  ....*....|
gi 116007678  448 QLRDQRDRAE 457
Cdd:COG1579   160 ELEAEREELA 169
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 624-866 9.64e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 9.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  624 LQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHAdrdrafsEVEKIKEEMERTQATLGKSQLQHEKLQN 703
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-------RIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  704 SLDKAQNEVDHLQDKLDKACTENRRLVLekekltydydnLQSQldkALGQAARMQKERETLSLDTDRIREKLEKTQVQLG 783
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALL-----------LSPE---DFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  784 RIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKAL 863
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ...
gi 116007678  864 YAS 866
Cdd:COG4942   244 PAA 246
46 PHA02562
endonuclease subunit; Provisional
 698-875 1.74e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 1.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  698 HEKLQNSLDKAQNE-VDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLD------KALGQA-ARMQKERETLS---- 765
Cdd:PHA02562  200 YNKNIEEQRKKNGEnIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEdpsaalNKLNTAaAKIKSKIEQFQkvik 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  766 ------------LDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKA---ARDREAMQTDLEVLKER 830
Cdd:PHA02562  280 myekggvcptctQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLlelKNKISTNKQSLITLVDK 359

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 116007678  831 YEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDT 875
Cdd:PHA02562  360 AKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYH 404
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 626-1112 2.04e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   626 EKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSL 705
Cdd:TIGR04523  211 QKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   706 DKAQNEVDHL-----QDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQV 780
Cdd:TIGR04523  291 NQLKSEISDLnnqkeQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQN 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   781 QLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKld 860
Cdd:TIGR04523  371 EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ-- 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   861 kaLYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIyrlqsrcdtaeadraRLEVEAERSGLAASKarEDLRKLQDESTRLQ 940
Cdd:TIGR04523  449 --DSVKELIIKNLDNTRESLETQLKVLSRSINKI---------------KQNLEQKQKELKSKE--KELKKLNEEKKELE 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   941 EACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGE--KEHFQSELERVTYELERAHAAQTKASASVEAAKE 1018
Cdd:TIGR04523  510 EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1019 EAAHYAVELEKMRDRYEKSQVELRKLQdtdtfgRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEK 1098
Cdd:TIGR04523  590 LIDQKEKEKKDLIKEIEEKEKKISSLE------KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPE 663

                          490
                   ....*....|....
gi 116007678  1099 IEMEVQNMESKLHE 1112
Cdd:TIGR04523  664 IIKKIKESKTKIDD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 461-686 2.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  461 QEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQR 540
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  541 IARLELENERLKHDLERSQNVQKLMFetgkISTTFGRTTMTTSQELDRAQERADKASAE-LRRTQAELRVTQSDAERARE 619
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQPPLAL----LLSPEDFLDAVRRLQYLKYLAPARREQAEeLRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116007678  620 EAAALQEKLEKSQGevyRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMER 686
Cdd:COG4942   175 ELEALLAELEEERA---ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
mukB PRK04863
chromosome partition protein MukB;
906-1304 2.33e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 2.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  906 ADRARLEVEAERSGLAASKAREDL----RKLQDESTRLQEACDRAALQLSRAKECEDnarsELEHSRDRFDKLQTDiRRA 981
Cdd:PRK04863  272 ADYMRHANERRVHLEEALELRRELytsrRQLAAEQYRLVEMARELAELNEAESDLEQ----DYQAASDHLNLVQTA-LRQ 346

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  982 QGEKEHFQSELERVTYELERAHAAqtkasasVEAAKEEAAhyavELEKMRDRYEKSQVELRKlQDTDTFGR----ETRRL 1057
Cdd:PRK04863  347 QEKIERYQADLEELEERLEEQNEV-------VEEADEQQE----ENEARAEAAEEEVDELKS-QLADYQQAldvqQTRAI 414

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1058 KEENERlrekldKTLMELETIRGKSQYESESFEKYKDKYekiemevQNMESKLHETSLQLElSKGEVAKMLANQEKQRSE 1137
Cdd:PRK04863  415 QYQQAV------QALERAKQLCGLPDLTADNAEDWLEEF-------QAKEQEATEELLSLE-QKLSVAQAAHSQFEQAYQ 480

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1138 LERA---HIEREKARDKHEKLLKEVDRLRLQQSSVSPgdpvRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEA 1214
Cdd:PRK04863  481 LVRKiagEVSRSEAWDVARELLRRLREQRHLAEQLQQ----LRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1215 GRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAE----REALRQANRSGGAGAAPHPQLEKHVQKL 1290
Cdd:PRK04863  557 EQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAwlaaQDALARLREQSGEEFEDSQDVTEYMQQL 636

                         410
                  ....*....|....
gi 116007678 1291 ESDVKQLAMEREQL 1304
Cdd:PRK04863  637 LERERELTVERDEL 650
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 413-665 2.88e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 2.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  413 MARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAehekQEERDLHEREVADYKIKLRAAESEVEKLQTRL 492
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKAL----LKQLAALERRIAALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  493 ERAVTERERLEIKLEASQSELgkskAELEKATCEMGRSSA-----DWESTKQRIARLELENERLKHDLERSQNVQKlmfe 567
Cdd:COG4942    86 AELEKEIAELRAELEAQKEEL----AELLRALYRLGRQPPlalllSPEDFLDAVRRLQYLKYLAPARREQAEELRA---- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  568 tgkisttfgrttmtTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQG 647
Cdd:COG4942   158 --------------DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                         250
                  ....*....|....*...
gi 116007678  648 EQESLRQELEKAQSGVSR 665
Cdd:COG4942   224 ELEALIARLEAEAAAAAE 241
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 645-923 3.10e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  645 AQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKact 724
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE--- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  725 enrrlvlekekltydydnlqsqldkalgQAARMQKERETLS-----LDTDRIREKLEKTQVqLGRIQKERDQFSDELETL 799
Cdd:COG3883    91 ----------------------------RARALYRSGGSVSyldvlLGSESFSDFLDRLSA-LSKIADADADLLEELKAD 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  800 KERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKE 879
Cdd:COG3883   142 KAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 116007678  880 FEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAAS 923
Cdd:COG3883   222 AAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAA 265
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 367-508 3.44e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 3.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  367 QERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGA---------LTSLEE 437
Cdd:COG1579    24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNkeyealqkeIESLKR 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116007678  438 AIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEA 508
Cdd:COG1579   104 RISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1190-1379 3.51e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1190 RQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQA 1269
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1270 -----------NRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRK 1338
Cdd:COG4942   106 laellralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 116007678 1339 LRNGHQVPPVAAPPAGPS-PAEFQAMQKEIQTLQQKLQESER 1379
Cdd:COG4942   186 ERAALEALKAERQKLLARlEKELAELAAELAELQQEAEELEA 227
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
303-425 4.47e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 4.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  303 AAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEkktqgtlqtvqernRLTSELTELKDH 382
Cdd:COG2433   391 PEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIE--------------RLERELSEARSE 456

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 116007678  383 MDI---KDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHH 425
Cdd:COG2433   457 ERReirKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1481-1731 5.20e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1481 KELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAgagat 1560
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE----- 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1561 dvQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEfdvQLRKRKEQMDQLEKSLQTQ 1640
Cdd:COG1196   314 --LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE---AEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1641 GGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAKVKQA 1720
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250
                  ....*....|.
gi 116007678 1721 QTQQQQQQDAG 1731
Cdd:COG1196   469 LEEAALLEAAL 479
PHA00430 PHA00430
tail fiber protein
 921-1050 7.08e-04

tail fiber protein


Pssm-ID: 222790 [Multi-domain]  Cd Length: 568  Bit Score: 44.50  E-value: 7.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  921 AASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELE 1000
Cdd:PHA00430  167 EANRSRNEADRARNQAERFNNESGASATNTKQWRSEADGSNSEANRFKGYADSMTSSVEAAKGQAESSSKEANTAGDYAT 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 116007678 1001 RAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTF 1050
Cdd:PHA00430  247 KAAASASAAHASEVNAANSATAAATSANRAKQQADRAKTEADKLGNMNGF 296
PLN02939 PLN02939
transferase, transferring glycosyl groups
 198-487 7.61e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.51  E-value: 7.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  198 LRMRQPNLEMQQQMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIaRDESIKKLLEMLQakgmgkeeerqmfqqm 277
Cdd:PLN02939  145 LLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQEKI-HVEILEEQLEKLR---------------- 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  278 qamaqkqlDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTdVEEMRARLEEKNRLIEK 357
Cdd:PLN02939  208 --------NELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFK-LEKERSLLDASLRELES 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  358 KtqgtLQTVQErnrltseltelkDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEE 437
Cdd:PLN02939  279 K----FIVAQE------------DVSKLSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKE 342

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 116007678  438 AIGDK---------EKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEK 487
Cdd:PLN02939  343 ANVSKfssykvellQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKK 401
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 493-1256 7.91e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   493 ERAVTERERLEIKLEASQSELGKSKAEL---EKATCEMGRSSADWESTKQRIARL-----------ELENERLKHDLERS 558
Cdd:pfam12128  151 DRTLLGRERVELRSLARQFALCDSESPLrhiDKIAKAMHSKEGKFRDVKSMIVAIleddgvvppksRLNRQQVEHWIRDI 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   559 QNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELR--RTQAELRVTQSDAERA-REEAAALQEKLEKSQGEV 635
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLiaSRQEERQETSAELNQLlRTLDDQWKEKRDELNGEL 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   636 YRLKAKLENAQGEQESLR-QELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNE-VD 713
Cdd:pfam12128  311 SAADAAVAKDRSELEALEdQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNR 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   714 HLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKEREtlsldtDRIREKLEKTQVQLGRIQKERDQFS 793
Cdd:pfam12128  391 DIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEE------YRLKSRLGELKLRLNQATATPELLL 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   794 DeLETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKShaiqqklqmerDDAVTEVEILKEKLDKALYASQKLIDEK 873
Cdd:pfam12128  465 Q-LENFDERIERAREEQEAANAEVERLQSELRQARKRRDQA-----------SEALRQASRRLEERQSALDELELQLFPQ 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   874 DTSNKEFEKMlEKYDRAQNeIYRLQSRCDTAEADRARLEVEAERSG-LAASKAREDLRKLQDESTRLQEacdraalqlsr 952
Cdd:pfam12128  533 AGTLLHFLRK-EAPDWEQS-IGKVISPELLHRTDLDPEVWDGSVGGeLNLYGVKLDLKRIDVPEWAASE----------- 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   953 akecednarselEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRD 1032
Cdd:pfam12128  600 ------------EELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKD 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1033 RYEKSQVELRKLQDTD--TFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKL 1110
Cdd:pfam12128  668 KKNKALAERKDSANERlnSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKA 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1111 HETSLQLEL-----SKGEVAKMLANQEKQRSELERAhIEReKARDKHEKLLKEvdrlRLQQSSVSPGDPVRASTSSSSAL 1185
Cdd:pfam12128  748 ELKALETWYkrdlaSLGVDPDVIAKLKREIRTLERK-IER-IAVRRQEVLRYF----DWYQETWLQRRPRLATQLSNIER 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1186 SAGE-RQEIDRL----RDRLEKALQSRDATELEAGRLAKELEK--------AQMHLAKQQENTESTRIEFERMGAELGRL 1252
Cdd:pfam12128  822 AISElQQQLARLiadtKLRRAKLEMERKASEKQQVRLSENLRGlrcemsklATLKEDANSEQAQGSIGERLAQLEDLKLK 901


                   ....
gi 116007678  1253 HDRL 1256
Cdd:pfam12128  902 RDYL 905
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 584-806 8.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 8.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  584 QELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGV 663
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  664 SRIHADRDRAfsevekikeeMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNL 743
Cdd:COG4942   107 AELLRALYRL----------GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 116007678  744 QSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESA 806
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 178-844 9.82e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 9.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   178 LSTENQKQAMLVRQLEEELRLRMRQPN---LEMQQQMEAIYAENDHLQREISILRETIKDLEcRVETQKQTLIARDESIK 254
Cdd:TIGR00606  403 QEDEAKTAAQLCADLQSKERLKQEQADeirDEKKGLGRTIELKKEILEKKQEELKFVIKELQ-QLEGSSDRILELDQELR 481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   255 K------------LLEMLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAV 322
Cdd:TIGR00606  482 KaerelskaeknsLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDE 561

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   323 LKESLC------AKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMdIKDRKISVLQRK 396
Cdd:TIGR00606  562 LTSLLGyfpnkkQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL-FDVCGSQDEESD 640

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   397 IENLEDLLKEKDNQvdmaRARLSAMQAHHSSSEGALTsleeaigDKEKQMAQLRDQRDRAEHEKQEErdlhereVADYKI 476
Cdd:TIGR00606  641 LERLKEEIEKSSKQ----RAMLAGATAVYSQFITQLT-------DENQSCCPVCQRVFQTEAELQEF-------ISDLQS 702

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   477 KLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAEL-------EKATCEMGRSSADWESTKQRIARLELENE 549
Cdd:TIGR00606  703 KLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIpelrnklQKVNRDIQRLKNDIEEQETLLGTIMPEEE 782

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   550 RLKHDLERSQNVQKLMFETGKISTT-FGRTTMTTSQELDRA-----QERADKaSAELRRTQAELRVTQSDAERAREEAAA 623
Cdd:TIGR00606  783 SAKVCLTDVTIMERFQMELKDVERKiAQQAAKLQGSDLDRTvqqvnQEKQEK-QHELDTVVSKIELNRKLIQDQQEQIQH 861

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   624 LQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQN 703
Cdd:TIGR00606  862 LKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   704 SLDKAQNEVD----HLQDKLDKACTENRRLVLEKEKltyDYDNLQSQLDKALGQAARMQKERETL--SLDTDRIREKLEK 777
Cdd:TIGR00606  942 KVNDIKEKVKnihgYMKDIENKIQDGKDDYLKQKET---ELNTVNAQLEECEKHQEKINEDMRLMrqDIDTQKIQERWLQ 1018

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116007678   778 TQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDReaMQTDLEVLKERYEKSHAIQQKLQME 844
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQK--LEENIDLIKRNHVLALGRQKGYEKE 1083
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 285-517 1.00e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  285 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQ--GT 362
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEelAE 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  363 LQTVQERNRLTSELTELKDHMDIKDrkisvLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDK 442
Cdd:COG4942   109 LLRALYRLGRQPPLALLLSPEDFLD-----AVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEL 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116007678  443 EKQMAQLRDQRDraehEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSK 517
Cdd:COG4942   184 EEERAALEALKA----ERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
337-512 1.09e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  337 LQTDVEEMRARLEEKNRLIEKkTQGTLQTVQERNRLTSELTELKDHmdikDRKISVLQRKIENLEDLLKE---KDNQVDM 413
Cdd:COG4913   615 LEAELAELEEELAEAEERLEA-LEAELDALQERREALQRLAEYSWD----EIDVASAEREIAELEAELERldaSSDDLAA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  414 ARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADY------KIKLRAAESEV-E 486
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleerfaAALGDAVERELrE 769

                         170       180
                  ....*....|....*....|....*.
gi 116007678  487 KLQTRLERAVTERERLEIKLEASQSE 512
Cdd:COG4913   770 NLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 640-872 1.17e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  640 AKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKL 719
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  720 DKactenrrlvlekekltydydnLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETL 799
Cdd:COG4942   100 EA---------------------QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 116007678  800 KERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDE 872
Cdd:COG4942   159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 714-872 1.18e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  714 HLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRI--QKERDQ 791
Cdd:COG1579    14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  792 FSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLID 871
Cdd:COG1579    94 LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173


                  .
gi 116007678  872 E 872
Cdd:COG1579   174 P 174
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
285-498 1.27e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  285 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRhiavlKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEK--KTQGT 362
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQE-----RREALQRLAEYSWDEIDVASAEREIAELEAELERldASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  363 LQTVQER-NRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDmararlsamQAHHSSSEGALTSLEEaigd 441
Cdd:COG4913   687 LAALEEQlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE---------AAEDLARLELRALLEE---- 753

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 116007678  442 kekqmaqLRDQRDRAEHEKQEERDLHERevadykikLRAAESEVEKLQTRLERAVTE 498
Cdd:COG4913   754 -------RFAAALGDAVERELRENLEER--------IDALRARLNRAEEELERAMRA 795
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 596-819 1.36e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 1.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  596 ASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQsgvsrihADRDRAFS 675
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE-------AEIEERRE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  676 EVEKIKEEMERTQATLGKSQ--LQHEKLQNSLDKAQNevdhlqdkLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQ 753
Cdd:COG3883    87 ELGERARALYRSGGSVSYLDvlLGSESFSDFLDRLSA--------LSKIADADADLLEELKADKAELEAKKAELEAKLAE 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678  754 AARMQKERETLsldTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREA 819
Cdd:COG3883   159 LEALKAELEAA---KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
285-485 2.40e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 2.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  285 LDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHiavlkeslcakeEHYNMLQTDVEEMRARLEEKNRLIEK--KTQGT 362
Cdd:COG4913   619 LAELEEELAEAEERLEALEAELDALQERREALQRL------------AEYSWDEIDVASAEREIAELEAELERldASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  363 LQTVQER-NRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDmaraRLSAMQAHHSSSEGALTSLEEAIGD 441
Cdd:COG4913   687 LAALEEQlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLEERFAAALGDA 762

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 116007678  442 KEKQM-AQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEV 485
Cdd:COG4913   763 VERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETADL 807
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1193-1404 2.43e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 2.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1193 IDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRS 1272
Cdd:COG4372    26 IAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELES 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1273 GGAGAAphpQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAAPP 1352
Cdd:COG4372   106 LQEEAE---ELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAE 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 116007678 1353 AGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQ 1404
Cdd:COG4372   183 QALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLA 234
46 PHA02562
endonuclease subunit; Provisional
 297-522 2.50e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.69  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  297 QEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAK-EEHYNMLQTDVEEMRARLEEKNRLIEKktqgTLQTVQERNRLTSE 375
Cdd:PHA02562  181 QQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEELTDE----LLNLVMDIEDPSAA 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  376 LTELKDHMDIKDRKISVLQRKIENLED---------LLKEKDNQVDMARARLSAMQahhssseGALTSLEEAIGDKEKQM 446
Cdd:PHA02562  257 LNKLNTAAAKIKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQ-------HSLEKLDTAIDELEEIM 329

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678  447 AQLRDQRDRAeHEKQEERDLHEREVADYKIKLRAAESEVEKLQtrlERAVTERERLEiKLEASQSELGKSKAELEK 522
Cdd:PHA02562  330 DEFNEQSKKL-LELKNKISTNKQSLITLVDKAKKVKAAIEELQ---AEFVDNAEELA-KLQDELDKIVKTKSELVK 400
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1481-1716 2.55e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 2.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1481 KELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGAT 1560
Cdd:COG1196   260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1561 DVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEfdvQLRKRKEQMDQLEKSLQTQ 1640
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---LAAQLEELEEAEEALLERL 416

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 116007678 1641 GGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAK 1716
Cdd:COG1196   417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 297-545 2.97e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 2.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  297 QEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKE--EHYnmlQTDVEEMRARLEEKNRLIEkKTQGTLQTVQERNRLT- 373
Cdd:COG3096   313 RELEELSARESDLEQDYQAASDHLNLVQTALRQQEkiERY---QEDLEELTERLEEQEEVVE-EAAEQLAEAEARLEAAe 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  374 SELTELKDHMDIKDRKISVLQRK------------------------IENLEDLL-------KEKDNQVDMARARLSAMQ 422
Cdd:COG3096   389 EEVDSLKSQLADYQQALDVQQTRaiqyqqavqalekaralcglpdltPENAEDYLaafrakeQQATEEVLELEQKLSVAD 468

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  423 AHHSSSEGALTSLEEAIGDKEKQMA---------QLRDQRDRAEHEKQEERDLHEREVADYkiKLRAAESEVEKLQTRLE 493
Cdd:COG3096   469 AARRQFEKAYELVCKIAGEVERSQAwqtarellrRYRSQQALAQRLQQLRAQLAELEQRLR--QQQNAERLLEEFCQRIG 546

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 116007678  494 RAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLE 545
Cdd:COG3096   547 QQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELA 598
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
587-855 3.08e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  587 DRAQERADKASAELRRTQAELRVTQSDAERA--REEAAALQEKLEKSQGEV--YRLKAKLENAQGEQESLRQELEKAQSG 662
Cdd:COG3206   148 ELAAAVANALAEAYLEQNLELRREEARKALEflEEQLPELRKELEEAEAALeeFRQKNGLVDLSEEAKLLLQQLSELESQ 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  663 VSRIHADRDRAFSEVEKIKEEMERTQATLGkSQLQHEKLQNsldkaqnevdhLQDKLDKActeNRRLVLEKEKLTY---D 739
Cdd:COG3206   228 LAEARAELAEAEARLAALRAQLGSGPDALP-ELLQSPVIQQ-----------LRAQLAEL---EAELAELSARYTPnhpD 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  740 YDNLQSQLDKALGQAARmqkeretlsldtdRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESaqtlLMKAARDREA 819
Cdd:COG3206   293 VIALRAQIAALRAQLQQ-------------EAQRILASLEAELEALQAREASLQAQLAQLEARLAE----LPELEAELRR 355

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 116007678  820 MQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEIL 855
Cdd:COG3206   356 LEREVEVARELYESLLQRLEEARLAEALTVGNVRVI 391
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 217-1072 3.09e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 3.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   217 ENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLE---MLQAKGMGKEEERQMFQQMQAMAQKQLDEFRLEIQ 293
Cdd:pfam02463  181 ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEeeyLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   294 RRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEhynmLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLT 373
Cdd:pfam02463  261 EKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK----SELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   374 SEltELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARArlsamqahhsssegALTSLEEAIGDKEKQMAQLRDQR 453
Cdd:pfam02463  337 IE--ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLA--------------KKKLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   454 DRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSAD 533
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   534 WESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSD 613
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   614 AERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGK 693
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   694 SQLQHEKLQN--SLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRI 771
Cdd:pfam02463  641 AKAKESGLRKgvSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   772 REKLEKTQVQLGRIQ---KERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDA 848
Cdd:pfam02463  721 ELLADRVQEAQDKINeelKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   849 VTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKARED 928
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   929 LRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTK 1008
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116007678  1009 ASASVEAAKEEAAhYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTL 1072
Cdd:pfam02463  961 RNKRLLLAKEELG-KVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFL 1023
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
850-1341 3.75e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 3.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  850 TEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDL 929
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLE 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  930 RKLQDESTRLQEACDRAALQLSRAKECEDNAR--SELEHSRDRFDKLqtdirraqgekEHFQSELERVTYELERAHAAQT 1007
Cdd:PRK03918  252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL-----------SEFYEEYLDELREIEKRLSRLE 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1008 KASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLdkTLMELETIRGKSQYESE 1087
Cdd:PRK03918  321 EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRL--TGLTPEKLEKELEELEK 398

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1088 SFEKYKDKYEKIEMEVQNMESKLHETSLQL---------------ELSKGEVAKMLANQEKQRSELERAHIEREKARDKH 1152
Cdd:PRK03918  399 AKEEIEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKL 478

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1153 EKLLKEVDRLRLQQSSVSPgdpvrastssssalsagERQEIDRLRDrLEKALQSRDATELEA-GRLAKELEKAQMHLAKQ 1231
Cdd:PRK03918  479 RKELRELEKVLKKESELIK-----------------LKELAEQLKE-LEEKLKKYNLEELEKkAEEYEKLKEKLIKLKGE 540

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1232 QENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPhpQLEKHVQKLESDVKQLaMEREQLVLQLEKS 1311
Cdd:PRK03918  541 IKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVE--ELEERLKELEPFYNEY-LELKDAEKELERE 617

                         490       500       510
                  ....*....|....*....|....*....|
gi 116007678 1312 QEILMNFQKELQNAEAELQKTREENRKLRN 1341
Cdd:PRK03918  618 EKELKKLEEELDKAFEELAETEKRLEELRK 647
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
584-802 3.76e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  584 QELDRAQERADKASAELRRTQAELRVTQSdaerareeaaALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGV 663
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRELAER----------YAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAEL 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  664 SRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQheklqnSLDKAQNEVDHLQDKLDKActENRRLVLEK--EKLTYDYD 741
Cdd:COG4913   305 ARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEER--ERRRARLEAllAALGLPLP 376

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116007678  742 NLQSQLDKALGQAARMqkeRETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKER 802
Cdd:COG4913   377 ASAEEFAALRAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 367-563 3.86e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 3.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  367 QERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQM 446
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  447 AQLRDQRdraeheKQEERDLHEREVADYKIKLRAAES--EVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKAT 524
Cdd:COG4942   100 EAQKEEL------AELLRALYRLGRQPPLALLLSPEDflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 116007678  525 CEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQK 563
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELA 212
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 584-1256 4.05e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 4.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   584 QELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQgEVYRLKAKLENAQGEQESLRQELEKAQSGV 663
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIE-ELRAQEAVLEETQERINRARKAAPLAAHIK 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   664 SRIHADRDRAFSEVEKIKEEMERTQ-----ATLGKSQLQHEKLQNSLDKAQNEVDHLQ----------DKLDKACTENRR 728
Cdd:TIGR00618  301 AVTQIEQQAQRIHTELQSKMRSRAKllmkrAAHVKQQSSIEEQRRLLQTLHSQEIHIRdahevatsirEISCQQHTLTQH 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   729 LVLEKEKLTYDYDNLQSqLDKALGQAARMQKERETLSLDTDRIREKL---EKTQVQLGRIQKERDQFSDELETLKERSES 805
Cdd:TIGR00618  381 IHTLQQQKTTLTQKLQS-LCKELDILQREQATIDTRTSAFRDLQGQLahaKKQQELQQRYAELCAAAITCTAQCEKLEKI 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   806 AQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYAS----------QKLIDEKDT 875
Cdd:TIGR00618  460 HLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIdnpgpltrrmQRGEQTYAQ 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   876 SNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKE 955
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLR 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   956 cednarsELEHSRDRFDKLQTD---IRRAQGEKEHFQSELERVTYELERAHAAQTKasasvEAAKEEAAHYAVELEKMRD 1032
Cdd:TIGR00618  620 -------KLQPEQDLQDVRLHLqqcSQELALKLTALHALQLTLTQERVREHALSIR-----VLPKELLASRQLALQKMQS 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1033 RYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMEL-ETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLH 1111
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLgSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1112 ETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDpvRASTSSSSALSAGERQ 1191
Cdd:TIGR00618  768 EEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE--EEQFLSRLEEKSATLG 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  1192 EIDRLRDRLEKALQSRDATELEAGRLAKELEKAQ--------------------------MHLAKQQENTESTRIEFERM 1245
Cdd:TIGR00618  846 EITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNginqikiqfdgdalikflheitlyanVRLANQSEGRFHGRYADSHV 925

                          730
                   ....*....|.
gi 116007678  1246 GAELGRLHDRL 1256
Cdd:TIGR00618  926 NARKYQGLALL 936
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 585-762 4.52e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 4.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  585 ELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKA----- 659
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraly 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  660 ------------------------QSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEvdhL 715
Cdd:COG3883    97 rsggsvsyldvllgsesfsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE---L 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 116007678  716 QDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERE 762
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 337-543 4.72e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 4.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  337 LQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEkdnqvdmaRA 416
Cdd:COG3883    21 KQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE--------RA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  417 RLSAMQAHHSSSEGAL---TSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDL--HEREVADYKIKLRAAESEVEKLQTR 491
Cdd:COG3883    93 RALYRSGGSVSYLDVLlgsESFSDFLDRLSALSKIADADADLLEELKADKAELeaKKAELEAKLAELEALKAELEAAKAE 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 116007678  492 LERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIAR 543
Cdd:COG3883   173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 224-790 4.83e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 4.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   224 EISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKG---MGKEEERQMFQQMQAMAQKQLDEFRLEIQRRDQEIL 300
Cdd:TIGR04523   76 KIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKeqkNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELE 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   301 AMAAKMKTLEEQHQDYQRHIAVLKE------------------------SLCAKEEHYNMLQTDVEEMRARLEEKNRLIE 356
Cdd:TIGR04523  156 KLNNKYNDLKKQKEELENELNLLEKeklniqknidkiknkllklelllsNLKKKIQKNKSLESQISELKKQNNQLKDNIE 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   357 KKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQahHSSSEGALTSLE 436
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELK 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   437 EAIGDKEKQMAQLRDQRDraehEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKS 516
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQIS----QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   517 KAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKa 596
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLET- 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   597 saELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSE 676
Cdd:TIGR04523  469 --QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   677 VEKIKEEMERTQATLGKSQLQHE--KLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKAlgqa 754
Cdd:TIGR04523  547 LNKDDFELKKENLEKEIDEKNKEieELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA---- 622

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 116007678   755 armQKERETLSLDTDRIREKLEKTQVQLGRIQKERD 790
Cdd:TIGR04523  623 ---KKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
PRK11281 PRK11281
mechanosensitive channel MscK;
699-814 4.83e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 4.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  699 EKLQNSLDKAQNEVDH-LQDKLDKACTENRRLVLEK-EKLTYDYDNLQSQLDKALGQAARMQKERETL------------ 764
Cdd:PRK11281   39 ADVQAQLDALNKQKLLeAEDKLVQQDLEQTLALLDKiDRQKEETEQLKQQLAQAPAKLRQAQAELEALkddndeetretl 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 116007678  765 -SLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAA 814
Cdd:PRK11281  119 sTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANS 169
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
624-1039 5.16e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  624 LQEKLEKSQGEVYRLKAKL-ENAQGEQESLRQELEKAQSGVSRIHADRDRaFSEVEKIKEEMERTQATLGKSQLQHEKLQ 702
Cdd:COG4717    47 LLERLEKEADELFKPQGRKpELNLKELKELEEELKEAEEKEEEYAELQEE-LEELEEELEELEAELEELREELEKLEKLL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  703 NSLD------KAQNEVDHLQDKLDKA---CTENRRLVLEKEKLTYDYDNLQSQLDKAL--------GQAARMQKERETLS 765
Cdd:COG4717   126 QLLPlyqeleALEAELAELPERLEELeerLEELRELEEELEELEAELAELQEELEELLeqlslateEELQDLAEELEELQ 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  766 LDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQ---------TLLMKAARDREAMQTDLEVLK-------- 828
Cdd:COG4717   206 QRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaALLALLGLGGSLLSLILTIAGvlflvlgl 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  829 -----ERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEI------YRL 897
Cdd:COG4717   286 lallfLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAeeleeeLQL 365

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  898 QSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAA--LQLSRAKECEDNARSELEHSRDRFDKLQ 975
Cdd:COG4717   366 EELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLgeLEELLEALDEEELEEELEELEEELEELE 445

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116007678  976 TDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVE-----LEKMRDRYEKSQV 1039
Cdd:COG4717   446 EELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKlalelLEEAREEYREERL 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
920-1171 5.40e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 5.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  920 LAASKAREDLRKLQDESTRLqeacDRAALQLSRAKECEDnARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYEL 999
Cdd:COG4913   218 LEEPDTFEAADALVEHFDDL----ERAHEALEDAREQIE-LLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1000 ERAHAAQTKASASVEAAKEEAAhyAVELEKMRDRYEKSQVELRKLQdtdtfGRETRRLKEENERLREKLDKTLMELetir 1079
Cdd:COG4913   293 LEAELEELRAELARLEAELERL--EARLDALREELDELEAQIRGNG-----GDRLEQLEREIERLERELEERERRR---- 361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1080 gksqyesesfEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAhieREKARDKHEKLLKEV 1159
Cdd:COG4913   362 ----------ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA---LRDLRRELRELEAEI 428

                         250
                  ....*....|..
gi 116007678 1160 DRLRLQQSSVSP 1171
Cdd:COG4913   429 ASLERRKSNIPA 440
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 549-712 5.85e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 41.14  E-value: 5.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   549 ERLKHDLERSQNVQKLMFETGKI-STTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEK 627
Cdd:pfam05262  184 EALREDNEKGVNFRRDMTDLKEReSQEDAKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKP 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   628 LEKSQGEVYRLKAklENAQGEQESLRQELEKAQSGVSRihADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDK 707
Cdd:pfam05262  264 ADTSSPKEDKQVA--ENQKREIEKAQIEIKKNDEEALK--AKDHKAFDLKQESKASEKEAEDKELEAQKKREPVAEDLQK 339


                   ....*
gi 116007678   708 AQNEV 712
Cdd:pfam05262  340 TKPQV 344
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 454-665 6.12e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 6.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  454 DRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSAD 533
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  534 WESTKQRIARLE--LENERLKHDLERSQNVQKLMFETGKISTTFGRTTmttsQELDRAQERADKASAELRRTQAELRVTQ 611
Cdd:COG3883    95 LYRSGGSVSYLDvlLGSESFSDFLDRLSALSKIADADADLLEELKADK----AELEAKKAELEAKLAELEALKAELEAAK 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 116007678  612 SDaerareeaaaLQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSR 665
Cdd:COG3883   171 AE----------LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 813-1043 7.14e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  813 AARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEilkeKLDKALYASQKLIDEKDTSNKEFEKMLEkydRAQN 892
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA----ALERRIAALARRIRALEQELAALEAELA---ELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  893 EIYRLQSRCDTAEADRARLEVEAERSGlaaskaREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARsELEHSRDRFD 972
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALYRLG------RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELA 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 116007678  973 KLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRK 1043
Cdd:COG4942   164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
PRK12704 PRK12704
phosphodiesterase; Provisional
 1001-1159 7.73e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.92  E-value: 7.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1001 RAHAAQTKASASVEAAKEEAAHYAVELE-KMRDRYE--KSQVELRKLQDTDTFGRETRRLKEENERLREK---LDKTLME 1074
Cdd:PRK12704   32 KIKEAEEEAKRILEEAKKEAEAIKKEALlEAKEEIHklRNEFEKELRERRNELQKLEKRLLQKEENLDRKlelLEKREEE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678 1075 LETIRGKSQYESESFEKYKDKYEKIEMEVQNmesKLHETSlqlELSKGEVAKMLANQEKQRSELERAHIER---EKARDK 1151
Cdd:PRK12704  112 LEKKEKELEQKQQELEKKEEELEELIEEQLQ---ELERIS---GLTAEEAKEILLEKVEEEARHEAAVLIKeieEEAKEE 185


                  ....*...
gi 116007678 1152 HEKLLKEV 1159
Cdd:PRK12704  186 ADKKAKEI 193
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 638-722 8.96e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 40.48  E-value: 8.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678   638 LKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGK-SQLQHEKLQNSLDKAQNEVDHLQ 716
Cdd:TIGR04320  259 LQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQtAQNNLATAQAALANAEARLAKAK 338


                   ....*.
gi 116007678   717 DKLDKA 722
Cdd:TIGR04320  339 EALANL 344
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 738-894 9.29e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 9.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  738 YDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLM--KAAR 815
Cdd:COG1579    10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvRNNK 89

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116007678  816 DREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEI 894
Cdd:COG1579    90 EYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
340-494 9.46e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 40.61  E-value: 9.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116007678  340 DVEEMRARLeeknrlIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEkdnqvdmararls 419
Cdd:COG2433   364 DRDEVKARV------IRGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER------------- 424

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 116007678  420 aMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRdRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLER 494
Cdd:COG2433   425 -LEAEVEELEAELEEKDERIERLERELSEARSEE-RREIRKDREISRLDREIERLERELEEERERIEELKRKLER 497
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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