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Conserved domains on  [gi|98986447|ref|NP_001035744|]
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cyclin-dependent kinase inhibitor 2A isoform p16INK4a [Mus musculus]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 11429852)

ankyrin repeat domain-containing protein; ANK proteins mediate specific protein-protein interactions without necessarily recognizing specific primary sequences which allows for one ankyrin repeat domain to recognize and bind to a variety of intracellular substrates and may be involved in a wide array of functions

Gene Ontology:  GO:0005515
PubMed:  17176038
SCOP:  4000366

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
14-126 2.23e-23

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 93.09  E-value: 2.23e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGS 92
Cdd:COG0666  97 NGDLEIVKLLLEAGADVNARDKDGETPLHLaAYNGNLEIVKLLLEAGADVNAQDNDGNT-PLHLAAANGNLEIVKLLLEA 175

                        90       100       110
                ....*....|....*....|....*....|....
gi 98986447  93 GARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:COG0666 176 GADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
14-126 2.23e-23

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 93.09  E-value: 2.23e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGS 92
Cdd:COG0666  97 NGDLEIVKLLLEAGADVNARDKDGETPLHLaAYNGNLEIVKLLLEAGADVNAQDNDGNT-PLHLAAANGNLEIVKLLLEA 175

                        90       100       110
                ....*....|....*....|....*....|....
gi 98986447  93 GARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:COG0666 176 GADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 20-122 3.93e-09

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 54.20  E-value: 3.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQ-VMMMGNVHVAALLLNYGADSNCEDPTTfSRPVHDAAREGFLDTLVVLHGSGARLDV 98
Cdd:PHA02874 107 IKTILDCGIDVNIKDAELKTFLHyAIKKGDLESIKMLFEYGADVNIEDDNG-CYPIHIAIKHNFFDIIKLLLEKGAYANV 185

                         90       100
                 ....*....|....*....|....
gi 98986447   99 RDAWGRLPLDLAQERGHQDIVRYL 122
Cdd:PHA02874 186 KDNNGESPLHNAAEYGDYACIKLL 209
Ank_2 pfam12796
Ankyrin repeats (3 copies);
14-100 2.66e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 48.96  E-value: 2.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447    14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYG-ADSNCEDPTtfsrPVHDAAREGFLDTLVVLHG 91
Cdd:pfam12796   7 NGNLELVKLLLENGADANLQDKNGRTALHLaAKNGHLEIVKLLLEHAdVNLKDNGRT----ALHYAARSGHLEIVKLLLE 82


                  ....*....
gi 98986447    92 SGARLDVRD 100
Cdd:pfam12796  83 KGADINVKD 91
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
14-126 2.23e-23

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 93.09  E-value: 2.23e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGS 92
Cdd:COG0666  97 NGDLEIVKLLLEAGADVNARDKDGETPLHLaAYNGNLEIVKLLLEAGADVNAQDNDGNT-PLHLAAANGNLEIVKLLLEA 175

                        90       100       110
                ....*....|....*....|....*....|....
gi 98986447  93 GARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:COG0666 176 GADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
14-148 4.97e-21

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 86.93  E-value: 4.97e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGS 92
Cdd:COG0666 130 NGNLEIVKLLLEAGADVNAQDNDGNTPLHLaAANGNLEIVKLLLEAGADVNARDNDGET-PLHLAAENGHLEIVKLLLEA 208

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 98986447  93 GARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAGCSLCSAGWSLCTAGNVAQTDGH 148
Cdd:COG0666 209 GADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGA 264
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
15-126 1.40e-09

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 55.35  E-value: 1.40e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  15 GRVHDVRALLEAGVSPNAPNSFGRTPIQVMMMGNVHVAALLLNYGADSNCEDPTTFSRPVHDAAREGFLDTLVVLHGSGA 94
Cdd:COG0666  32 LLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGA 111

                        90       100       110
                ....*....|....*....|....*....|..
gi 98986447  95 RLDVRDAWGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:COG0666 112 DVNARDKDGETPLHLAAYNGNLEIVKLLLEAG 143
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 20-122 3.93e-09

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 54.20  E-value: 3.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQ-VMMMGNVHVAALLLNYGADSNCEDPTTfSRPVHDAAREGFLDTLVVLHGSGARLDV 98
Cdd:PHA02874 107 IKTILDCGIDVNIKDAELKTFLHyAIKKGDLESIKMLFEYGADVNIEDDNG-CYPIHIAIKHNFFDIIKLLLEKGAYANV 185

                         90       100
                 ....*....|....*....|....
gi 98986447   99 RDAWGRLPLDLAQERGHQDIVRYL 122
Cdd:PHA02874 186 KDNNGESPLHNAAEYGDYACIKLL 209
Ank_2 pfam12796
Ankyrin repeats (3 copies);
14-100 2.66e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 48.96  E-value: 2.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447    14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYG-ADSNCEDPTtfsrPVHDAAREGFLDTLVVLHG 91
Cdd:pfam12796   7 NGNLELVKLLLENGADANLQDKNGRTALHLaAKNGHLEIVKLLLEHAdVNLKDNGRT----ALHYAARSGHLEIVKLLLE 82


                  ....*....
gi 98986447    92 SGARLDVRD 100
Cdd:pfam12796  83 KGADINVKD 91
PHA03095 PHA03095
ankyrin-like protein; Provisional
 20-157 2.91e-08

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 51.95  E-value: 2.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQVMMMGN--VHVAALLLNYGADSNCEDPTTFSrPVH-----DAAREGFLDTLVVLhgs 92
Cdd:PHA03095  66 VRLLLEAGADVNAPERCGFTPLHLYLYNAttLDVIKLLIKAGADVNAKDKVGRT-PLHvylsgFNINPKVIRLLLRK--- 141

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 98986447   93 GARLDVRDAWGRLPLDLaqerghqdivrYLRSAGCS------LCSAGWSLCTAGNVAQTDGHSFSSST-PRA 157
Cdd:PHA03095 142 GADVNALDLYGMTPLAV-----------LLKSRNANvellrlLIDAGADVYAVDDRFRSLLHHHLQSFkPRA 202
Ank_2 pfam12796
Ankyrin repeats (3 copies);
47-129 3.38e-08

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 48.57  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447    47 GNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHgSGARLDVRDAwGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:pfam12796   8 GNLELVKLLLENGADANLQDKNGRT-ALHLAAKNGHLEIVKLLL-EHADVNLKDN-GRTALHYAARSGHLEIVKLLLEKG 84


                  ...
gi 98986447   127 CSL 129
Cdd:pfam12796  85 ADI 87
PHA03095 PHA03095
ankyrin-like protein; Provisional
 20-120 5.78e-08

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 50.79  E-value: 5.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQVMMMGNVHVAALLLNY---GADSNCEDPTTFSrPVHDAA---REGFLDTLVVLhgsG 93
Cdd:PHA03095 205 VRELIRAGCDPAATDMLGNTPLHSMATGSSCKRSLVLPLliaGISINARNRYGQT-PLHYAAvfnNPRACRRLIAL---G 280

                         90       100
                 ....*....|....*....|....*..
gi 98986447   94 ARLDVRDAWGRLPLDLAQERGHQDIVR 120
Cdd:PHA03095 281 ADINAVSSDGNTPLSLMVRNNNGRAVR 307
PHA03095 PHA03095
ankyrin-like protein; Provisional
 16-130 4.60e-07

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 48.48  E-value: 4.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   16 RVHDVRALLEAGVSPNAPNSFGRTPIQVMMMGNVH----VAALLLNYGADSNCEDPTTFSrPVH----DAAREGFLDTLV 87
Cdd:PHA03095  26 TVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSSEkvkdIVRLLLEAGADVNAPERCGFT-PLHlylyNATTLDVIKLLI 104

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 98986447   88 vlhGSGARLDVRDAWGRLPLD--LAQERGHQDIVRYLRSAGCSLC 130
Cdd:PHA03095 105 ---KAGADVNAKDKVGRTPLHvyLSGFNINPKVIRLLLRKGADVN 146
Ank_2 pfam12796
Ankyrin repeats (3 copies);
75-122 6.97e-07

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 45.11  E-value: 6.97e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 98986447    75 HDAAREGFLDTLVVLHGSGARLDVRDAWGRLPLDLAQERGHQDIVRYL 122
Cdd:pfam12796   2 HLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLL 49
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 20-129 2.81e-06

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 46.21  E-value: 2.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQVMMMGNVHVAAL--LLNYGADSNCEDpTTFSRPVHDAAR-EGFLDTLVVLHGSGARL 96
Cdd:PHA02876 290 VPKLLERGADVNAKNIKGETPLYLMAKNGYDTENIrtLIMLGADVNAAD-RLYITPLHQASTlDRNKDIVITLLELGANV 368

                         90       100       110
                 ....*....|....*....|....*....|...
gi 98986447   97 DVRDAWGRLPLDLAQERGHQDIVRYLRSAGCSL 129
Cdd:PHA02876 369 NARDYCDKTPIHYAAVRNNVVIINTLLDYGADI 401
Ank_4 pfam13637
Ankyrin repeats (many copies);
71-122 3.39e-06

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 42.26  E-value: 3.39e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 98986447    71 SRPVHDAAREGFLDTLVVLHGSGARLDVRDAWGRLPLDLAQERGHQDIVRYL 122
Cdd:pfam13637   2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 20-130 5.75e-06

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 45.27  E-value: 5.75e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQVM-MMGNVHVAALLLNYGADSNCEDpttfsrpvhdaaregfldtlvvlhgsgarldv 98
Cdd:PTZ00322  98 ARILLTGGADPNCRDYDGRTPLHIAcANGHVQVVRVLLEFGADPTLLD-------------------------------- 145

                         90       100       110
                 ....*....|....*....|....*....|..
gi 98986447   99 RDawGRLPLDLAQERGHQDIVRYLrsAGCSLC 130
Cdd:PTZ00322 146 KD--GKTPLELAEENGFREVVQLL--SRHSQC 173
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 20-122 9.37e-06

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 44.66  E-value: 9.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQVMMM---GNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDT----LVVLHGS 92
Cdd:PHA03100  89 VKLLLEYGANVNAPDNNGITPLLYAISkksNSYSIVEYLLDNGANVNIKNSDGEN-LLHLYLESNKIDLkilkLLIDKGV 167

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 98986447   93 --------------GARLDVRDAWGRLPLDLAQERGHQDIVRYL 122
Cdd:PHA03100 168 dinaknrvnyllsyGVPINIKDVYGFTPLHYAVYNNNPEFVKYL 211
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
14-101 6.80e-05

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 41.86  E-value: 6.80e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  14 QGRVHDVRALLEAGVSPNAPNSFGRTPIQV-MMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGS 92
Cdd:COG0666 196 NGHLEIVKLLLEAGADVNAKDNDGKTALDLaAENGNLEIVKLLLEAGADLNAKDKDGLT-ALLLAAAAGAALIVKLLLLA 274


                ....*....
gi 98986447  93 GARLDVRDA 101
Cdd:COG0666 275 LLLLAAALL 283
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 15-122 1.16e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 41.13  E-value: 1.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   15 GRVHDVRALLEAGVSPNAPNSFGRTPIQVMM-MGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGSG 93
Cdd:PHA02875  13 GELDIARRLLDIGINPNFEIYDGISPIKLAMkFRDSEAIKLLMKHGAIPDVKYPDIES-ELHDAVEEGDVKAVEELLDLG 91

                         90       100       110
                 ....*....|....*....|....*....|
gi 98986447   94 ARL-DVRDAWGRLPLDLAQERGHQDIVRYL 122
Cdd:PHA02875  92 KFAdDVFYKDGMTPLHLATILKKLDIMKLL 121
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 14-126 1.87e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 40.74  E-value: 1.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   14 QGRVHDVRALLEAGVSPNapNSF---GRTPIQV-MMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVL 89
Cdd:PHA02875  78 EGDVKAVEELLDLGKFAD--DVFykdGMTPLHLaTILKKLDIMKLLIARGADPDIPNTDKFS-PLHLAVMMGDIKGIELL 154

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 98986447   90 HGSGARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:PHA02875 155 IDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSG 191
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 41-139 3.51e-04

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 40.24  E-value: 3.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   41 IQVMMMGNVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGSGARLDVRDAWGRLPLDLAQERGHQDIVR 120
Cdd:PLN03192 530 LTVASTGNAALLEELLKAKLDPDIGDSKGRT-PLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFR 608

                         90       100
                 ....*....|....*....|.
gi 98986447  121 YLR--SAGCSLCSAGWSLCTA 139
Cdd:PLN03192 609 ILYhfASISDPHAAGDLLCTA 629
Ank_4 pfam13637
Ankyrin repeats (many copies);
15-56 1.06e-03

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 35.71  E-value: 1.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 98986447    15 GRVHDVRALLEAGVSPNAPNSFGRTPIQ-VMMMGNVHVAALLL 56
Cdd:pfam13637  12 GHLELLRLLLEKGADINAVDGNGETALHfAASNGNVEVLKLLL 54
PHA03095 PHA03095
ankyrin-like protein; Provisional
 20-129 1.62e-03

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 38.08  E-value: 1.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPNSFGRTPIQVMMM-GNVHVAAL-------------------LLNYGADSNCEDPTTFSR------- 72
Cdd:PHA03095 135 IRLLLRKGADVNALDLYGMTPLAVLLKsRNANVELLrllidagadvyavddrfrsLLHHHLQSFKPRARIVREliragcd 214

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 98986447   73 ----------PVHDAAREGFLDTLVV--LHGSGARLDVRDAWGRLPLDLAQERGHQDIVRYLRSAGCSL 129
Cdd:PHA03095 215 paatdmlgntPLHSMATGSSCKRSLVlpLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADI 283
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 23-63 2.15e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 37.74  E-value: 2.15e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 98986447   23 LLEAGVSPNAPNSFGRTPIQ-VMMMGNVHVAALLLNYGADSN 63
Cdd:PHA02876 164 LLEGGADVNAKDIYCITPIHyAAERGNAKMVNLLLSYGADVN 205
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
19-126 2.83e-03

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 37.24  E-value: 2.83e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447  19 DVRALLEAGVSPNAPNSFGRTPIQVMMMGNVHVAALLLNYGADSNCEDPTTFSRPVHDAAREGFLDTLVVLHGSGARLDV 98
Cdd:COG0666   3 LLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINA 82

                        90       100
                ....*....|....*....|....*...
gi 98986447  99 RDAWGRLPLDLAQERGHQDIVRYLRSAG 126
Cdd:COG0666  83 KDDGGNTLLHAAARNGDLEIVKLLLEAG 110
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 20-110 4.62e-03

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 36.78  E-value: 4.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 98986447   20 VRALLEAGVSPNAPN-SFGRTPIQVMMMG-NVHVAALLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGSGARLD 97
Cdd:PHA02878 150 TKLLLSYGADINMKDrHKGNTALHYATENkDQRLTELLLSYGANVNIPDKTNNS-PLHHAVKHYNKPIVHILLENGASTD 228

                         90
                 ....*....|...
gi 98986447   98 VRDAWGRLPLDLA 110
Cdd:PHA02878 229 ARDKCGNTPLHIS 241
Ank_5 pfam13857
Ankyrin repeats (many copies);
54-110 8.01e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 33.09  E-value: 8.01e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 98986447    54 LLLNYGADSNCEDPTTFSrPVHDAAREGFLDTLVVLHGSGARLDVRDAWGRLPLDLA 110
Cdd:pfam13857   1 LLEHGPIDLNRLDGEGYT-PLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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