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Conserved domains on  [gi|89179321|ref|NP_001034764|]
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protein unc-45 homolog A isoform 3 [Homo sapiens]

Protein Classification

UNC45-central domain-containing protein( domain architecture ID 10569479)

UNC45-central domain-containing protein similar to Homo sapiens SWI5-dependent HO expression protein 4 (SHE4) required for mother cell-specific ho expression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UNC45-central pfam11701
Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C. ...
 348-490 5.22e-31

Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C.elegans is expressed in two forms from different genomic positions in mammals, as a general tissue protein UNC-45a and a specific form Unc-45b expressed only in striated and skeletal muscle. All members carry up to three amino-terminal tetratricopeptide repeat (TPR) domains towards their N-terminal, a UCS domain at the C-terminal that contains a number of Arm repeats pfam00514 and this central region of approximately 400 residues. Both the general form and the muscle form of UNC-45 function in myotube formation through cell fusion. Myofibril formation requires both GC and SM UNC-45, consistent with the fact that the cytoskeleton is necessary for the development and maintenance of organized myofibrils. The S. pombe Rng3p, is crucial for cell shape, normal actin cytoskeleton, and contractile ring assembly, and is essential for assembly of the myosin II-containing progenitors of the contractile ring. Widespread defects in the cytoskeleton are found in null mutants of all three fungal proteins. Mammalian Unc45 is found to act as a specific chaperone during the folding of myosin and the assembly of striated muscle by forming a stable complex with the general chaperone Hsp90. The exact function of this central region is not known.


:

Pssm-ID: 432011  Cd Length: 151  Bit Score: 118.79  E-value: 5.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321   348 VTANSRMSASILLSKLfddlkCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESV 427
Cdd:pfam11701  14 LPESVRSLALLILSKL-----LEAAKEEFEEKFSEFITSLLADGTNDDLIIAFSALAALFPVPPDVASALFLSEGFLESL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 89179321   428 IALCAS-EQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKcSEKDSIRIRALVGLCKL 490
Cdd:pfam11701  89 LPLVESkKSRKVELAALELLSAACIDKACREAISKNYVDWLEELLK-SSDDEIKALAAVVLAKL 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
13-110 1.65e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.57  E-value: 1.65e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDP---DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90
                ....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKN 110
Cdd:COG4785 157 YELAIADLEKALELDPND 174
 
Name Accession Description Interval E-value
UNC45-central pfam11701
Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C. ...
 348-490 5.22e-31

Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C.elegans is expressed in two forms from different genomic positions in mammals, as a general tissue protein UNC-45a and a specific form Unc-45b expressed only in striated and skeletal muscle. All members carry up to three amino-terminal tetratricopeptide repeat (TPR) domains towards their N-terminal, a UCS domain at the C-terminal that contains a number of Arm repeats pfam00514 and this central region of approximately 400 residues. Both the general form and the muscle form of UNC-45 function in myotube formation through cell fusion. Myofibril formation requires both GC and SM UNC-45, consistent with the fact that the cytoskeleton is necessary for the development and maintenance of organized myofibrils. The S. pombe Rng3p, is crucial for cell shape, normal actin cytoskeleton, and contractile ring assembly, and is essential for assembly of the myosin II-containing progenitors of the contractile ring. Widespread defects in the cytoskeleton are found in null mutants of all three fungal proteins. Mammalian Unc45 is found to act as a specific chaperone during the folding of myosin and the assembly of striated muscle by forming a stable complex with the general chaperone Hsp90. The exact function of this central region is not known.


Pssm-ID: 432011  Cd Length: 151  Bit Score: 118.79  E-value: 5.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321   348 VTANSRMSASILLSKLfddlkCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESV 427
Cdd:pfam11701  14 LPESVRSLALLILSKL-----LEAAKEEFEEKFSEFITSLLADGTNDDLIIAFSALAALFPVPPDVASALFLSEGFLESL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 89179321   428 IALCAS-EQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKcSEKDSIRIRALVGLCKL 490
Cdd:pfam11701  89 LPLVESkKSRKVELAALELLSAACIDKACREAISKNYVDWLEELLK-SSDDEIKALAAVVLAKL 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
13-110 1.65e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.57  E-value: 1.65e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDP---DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90
                ....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKN 110
Cdd:COG4785 157 YELAIADLEKALELDPND 174
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 8-129 3.24e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 66.93  E-value: 3.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321     8 QLRKEGNELFKCGDYGGALAAYTQALGLDATPqdqaVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQAL 87
Cdd:TIGR00990 129 KLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP----VYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAY 204

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 89179321    88 EKLGRLDQAVLDLQ-RCVSLEPKNKVFQEAL-RNIGGQIQEKVR 129
Cdd:TIGR00990 205 DGLGKYADALLDLTaSCIIDGFRNEQSAQAVeRLLKKFAESKAK 248
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 9-151 4.88e-10

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 62.50  E-value: 4.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321    9 LRKEGNELFKCGDYGGALAAYTQALGLDATpqdQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALE 88
Cdd:PLN03088   5 LEDKAKEAFVDDDFALAVDLYTQAIDLDPN---NAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 89179321   89 KLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK----------VRYMSSTDAKVEQMFQILLDPEEK 151
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEekdlvqpvpsDLPSSVTAPPVEEADATPVVPPSK 154
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 11-76 1.48e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.78  E-value: 1.48e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 89179321    11 KEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGD 76
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 77-110 7.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 7.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 89179321     77 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN 110
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
UNC45-central pfam11701
Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C. ...
 348-490 5.22e-31

Myosin-binding striated muscle assembly central; The UNC-45 or small muscle protein 1 of C.elegans is expressed in two forms from different genomic positions in mammals, as a general tissue protein UNC-45a and a specific form Unc-45b expressed only in striated and skeletal muscle. All members carry up to three amino-terminal tetratricopeptide repeat (TPR) domains towards their N-terminal, a UCS domain at the C-terminal that contains a number of Arm repeats pfam00514 and this central region of approximately 400 residues. Both the general form and the muscle form of UNC-45 function in myotube formation through cell fusion. Myofibril formation requires both GC and SM UNC-45, consistent with the fact that the cytoskeleton is necessary for the development and maintenance of organized myofibrils. The S. pombe Rng3p, is crucial for cell shape, normal actin cytoskeleton, and contractile ring assembly, and is essential for assembly of the myosin II-containing progenitors of the contractile ring. Widespread defects in the cytoskeleton are found in null mutants of all three fungal proteins. Mammalian Unc45 is found to act as a specific chaperone during the folding of myosin and the assembly of striated muscle by forming a stable complex with the general chaperone Hsp90. The exact function of this central region is not known.


Pssm-ID: 432011  Cd Length: 151  Bit Score: 118.79  E-value: 5.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321   348 VTANSRMSASILLSKLfddlkCDAERENFHRLCENYIKSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESV 427
Cdd:pfam11701  14 LPESVRSLALLILSKL-----LEAAKEEFEEKFSEFITSLLADGTNDDLIIAFSALAALFPVPPDVASALFLSEGFLESL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 89179321   428 IALCAS-EQEEEQLVAVEALIHAAGKAKRASFITANGVSLLKDLYKcSEKDSIRIRALVGLCKL 490
Cdd:pfam11701  89 LPLVESkKSRKVELAALELLSAACIDKACREAISKNYVDWLEELLK-SSDDEIKALAAVVLAKL 151
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
13-110 1.65e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 79.57  E-value: 1.65e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDP---DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                        90
                ....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKN 110
Cdd:COG4785 157 YELAIADLEKALELDPND 174
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
13-121 3.20e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.20  E-value: 3.20e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG0457  15 GLAYRRLGRYEEAIEDYEKALELD---PDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGR 91

                        90       100
                ....*....|....*....|....*....
gi 89179321  93 LDQAVLDLQRCVSLEPKNkvfQEALRNIG 121
Cdd:COG0457  92 YEEALEDYDKALELDPDD---AEALYNLG 117
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-126 5.74e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 79.27  E-value: 5.74e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321   2 TASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALY 81
Cdd:COG3914  74 LLLLAALLELAALLLQALGRYEEALALYRRALALNP---DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYL 150

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 89179321  82 RRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNIG------GQIQE 126
Cdd:COG3914 151 NLGEALRRLGRLEEAIAALRRALELDPDN---AEALNNLGnalqdlGRLEE 198
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
13-201 3.36e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.50  E-value: 3.36e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG0457  49 GLAYLRLGRYEEALADYEQALELDP---DDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGR 125

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  93 LDQAVLDLQRCVSLEPKNkvfQEALRNIG------GQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVL 166
Cdd:COG0457 126 YDEAIEAYERALELDPDD---ADALYNLGialeklGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202

                       170       180       190
                ....*....|....*....|....*....|....*
gi 89179321 167 AREDAGAEKIFRSNGVQLLQRLLDMGETDLMLAAL 201
Cdd:COG0457 203 LEQALRKKLAILTLAALAELLLLALALLLALRLAA 237
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-178 1.02e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.95  E-value: 1.02e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG3914 119 GNLLLALGRLEEALAALRRALALNP---DFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGR 195

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  93 LDQAVLDLQRCVSLEPKN-KVFQEALRNiggqiqekvrYMSSTDAKVEQMFQILLdpeeKGTEKKQKASQNLVVLAREDA 171
Cdd:COG3914 196 LEEAIAAYRRALELDPDNaDAHSNLLFA----------LRQACDWEVYDRFEELL----AALARGPSELSPFALLYLPDD 261


                ....*..
gi 89179321 172 GAEKIFR 178
Cdd:COG3914 262 DPAELLA 268
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
13-177 5.41e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.95  E-value: 5.41e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG0457  83 GLALQALGRYEEALEDYDKALELDP---DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGR 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  93 LDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAG 172
Cdd:COG0457 160 YEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239


                ....*
gi 89179321 173 AEKIF 177
Cdd:COG0457 240 LYQYR 244
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
20-109 1.41e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 61.34  E-value: 1.41e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  20 GDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAEtEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLD 99
Cdd:COG3063   6 GDLEEAEEYYEKALELDP---DNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                        90
                ....*....|
gi 89179321 100 LQRCVSLEPK 109
Cdd:COG3063  82 LERALELDPS 91
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 8-129 3.24e-11

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 66.93  E-value: 3.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321     8 QLRKEGNELFKCGDYGGALAAYTQALGLDATPqdqaVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQAL 87
Cdd:TIGR00990 129 KLKEKGNKAYRNKDFNKAIKLYSKAIECKPDP----VYYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAY 204

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 89179321    88 EKLGRLDQAVLDLQ-RCVSLEPKNKVFQEAL-RNIGGQIQEKVR 129
Cdd:TIGR00990 205 DGLGKYADALLDLTaSCIIDGFRNEQSAQAVeRLLKKFAESKAK 248
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 16-108 4.55e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.90  E-value: 4.55e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  16 LFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQ 95
Cdd:COG5010  64 YNKLGDFEESLALLEQALQLDP---NNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDE 140

                        90
                ....*....|...
gi 89179321  96 AVLDLQRCVSLEP 108
Cdd:COG5010 141 AKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 13-120 8.52e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.40  E-value: 8.52e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRLDP---DNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGD 100

                        90       100
                ....*....|....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKNKVFQEALRNI 120
Cdd:COG4235 101 YAEAIAAWQKLLALLPADAPARLLEASI 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 3-110 2.02e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.82  E-value: 2.02e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321   3 ASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDAtpqDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYR 82
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDP---DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLN 77

                        90       100
                ....*....|....*....|....*...
gi 89179321  83 RSQALEKLGRLDQAVLDLQRCVSLEPKN 110
Cdd:COG4783  78 LGLALLKAGDYDEALALLEKALKLDPEH 105
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 9-151 4.88e-10

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 62.50  E-value: 4.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321    9 LRKEGNELFKCGDYGGALAAYTQALGLDATpqdQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALE 88
Cdd:PLN03088   5 LEDKAKEAFVDDDFALAVDLYTQAIDLDPN---NAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 89179321   89 KLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK----------VRYMSSTDAKVEQMFQILLDPEEK 151
Cdd:PLN03088  82 KLEEYQTAKAALEKGASLAPGDSRFTKLIKECDEKIAEEekdlvqpvpsDLPSSVTAPPVEEADATPVVPPSK 154
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 13-110 5.74e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.28  E-value: 5.74e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG4783  45 GEILLQLGDLDEAIVLLHEALELD---PDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGR 121

                        90
                ....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKN 110
Cdd:COG4783 122 PDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
41-121 1.54e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 59.64  E-value: 1.54e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  41 DQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNI 120
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD---AEALNNL 82


                .
gi 89179321 121 G 121
Cdd:COG0457  83 G 83
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
21-121 6.77e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.15  E-value: 6.77e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  21 DYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDL 100
Cdd:COG4785  51 AALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDF 130

                        90       100
                ....*....|....*....|.
gi 89179321 101 QRCVSLEPKNkvfQEALRNIG 121
Cdd:COG4785 131 DRALELDPDY---AYAYLNRG 148
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 13-110 9.43e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 9.43e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG2956 151 AELYLEQGDYDEAIEALEKALKLD---PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGD 227

                        90
                ....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKN 110
Cdd:COG2956 228 PEEALELLRKALELDPSD 245
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 20-120 1.13e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 1.13e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  20 GDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLD 99
Cdd:COG2956 124 GDWEKAIEVLERLLKLG---PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAA 200

                        90       100
                ....*....|....*....|.
gi 89179321 100 LQRCVSLEPKNKVFQEALRNI 120
Cdd:COG2956 201 LERALEQDPDYLPALPRLAEL 221
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 15-116 1.13e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 51.15  E-value: 1.13e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  15 ELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVK---ALYRRSQALEKLG 91
Cdd:COG1729   2 ALLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELG 81

                        90       100
                ....*....|....*....|....*
gi 89179321  92 RLDQAVLDLQRCVSLEPKNKVFQEA 116
Cdd:COG1729  82 DYDKARATLEELIKKYPDSEAAKEA 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 13-114 2.19e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.19  E-value: 2.19e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG2956  49 GNLYRRRGEYDRAIRIHQKLLERD---PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGD 125

                        90       100
                ....*....|....*....|..
gi 89179321  93 LDQAVLDLQRCVSLEPKNKVFQ 114
Cdd:COG2956 126 WEKAIEVLERLLKLGPENAHAY 147
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 42-121 2.24e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.96  E-value: 2.24e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  42 QAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNIG 121
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDE---PEARLNLG 79
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 25-121 1.07e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 1.07e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  25 ALAAYTQALGLDatPQDqAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCV 104
Cdd:COG4235   2 AIARLRQALAAN--PND-AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78

                        90
                ....*....|....*..
gi 89179321 105 SLEPKNkvfQEALRNIG 121
Cdd:COG4235  79 ALDPDN---PEALYLLG 92
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 12-120 1.82e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.50  E-value: 1.82e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  12 EGNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLG 91
Cdd:COG2956  14 KGLNYLLNGQPDKAIDLLEEALELD---PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                        90       100
                ....*....|....*....|....*....
gi 89179321  92 RLDQAVLDLQRCVSLEPKNKVFQEALRNI 120
Cdd:COG2956  91 LLDRAEELLEKLLELDPDDAEALRLLAEI 119
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 13-110 4.99e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 4.99e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDatPQDQAVLhRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG2956  83 AQDYLKAGLLDRAEELLEKLLELD--PDDAEAL-RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                        90
                ....*....|....*...
gi 89179321  93 LDQAVLDLQRCVSLEPKN 110
Cdd:COG2956 160 YDEAIEALEKALKLDPDC 177
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
52-121 5.04e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 45.93  E-value: 5.04e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  52 CHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAvLDLQRCVSLEPKNkvfQEALRNIG 121
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNN---AEALLNLA 66
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
13-102 6.20e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 6.20e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGLDatPQDQAVlHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGR 92
Cdd:COG4785 114 GLAYLLLGDYDAALEDFDRALELD--PDYAYA-YLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAERKLDP 190

                        90
                ....*....|
gi 89179321  93 lDQAVLDLQR 102
Cdd:COG4785 191 -EKALALLLE 199
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 25-121 8.55e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 8.55e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  25 ALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCV 104
Cdd:COG5010  36 NTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL 115

                        90
                ....*....|....*..
gi 89179321 105 SLEPKNkvfQEALRNIG 121
Cdd:COG5010 116 ALSPDN---PNAYSNLA 129
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 17-110 1.45e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.83  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321    17 FKC--GDYGGALAAYTQALGLDATPQDQAVlhrNRAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLD 94
Cdd:TIGR00990 340 FKClkGKHLEALADLSKSIELDPRVTQSYI---KRASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFA 416

                          90
                  ....*....|....*.
gi 89179321    95 QAVLDLQRCVSLEPKN 110
Cdd:TIGR00990 417 QAGKDYQKSIDLDPDF 432
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 25-121 1.04e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.14  E-value: 1.04e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  25 ALAAYTQALGLDATPQDQAVLHRNRAACHlKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCV 104
Cdd:COG3914  61 ALAAGEAAAAAAALLLLAALLELAALLLQ-ALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRAL 139

                        90
                ....*....|....*..
gi 89179321 105 SLEPKnkvFQEALRNIG 121
Cdd:COG3914 140 ALNPD---FAEAYLNLG 153
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 11-76 1.48e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.78  E-value: 1.48e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 89179321    11 KEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGD 76
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
13-96 1.56e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 44.49  E-value: 1.56e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  13 GNELFKCGDYGGALAAYTQALGlDATPQDQAVLHRnRAACHLKLEDYDKAETEASKAIEKD----GGDVKALYRRsqALE 88
Cdd:COG4700  96 ADALLELGRYDEAIELYEEALT-GIFADDPHILLG-LAQALFELGRYAEALETLEKLIAKNpdfkSSDAHLLYAR--ALE 171


                ....*...
gi 89179321  89 KLGRLDQA 96
Cdd:COG4700 172 ALGDLEAA 179
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 53-127 5.50e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 5.50e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 89179321  53 HLKLEDYDKAETEASKAIEKDGGDV---KALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIgGQIQEK 127
Cdd:COG1729   3 LLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKL-GLSYLE 79
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 61-150 9.58e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.37  E-value: 9.58e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  61 KAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNkvfQEALRNIGGqiqekVRYMSSTDAKVEQ 140
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAE-----ALLAAGDTEEAEE 72

                        90
                ....*....|..
gi 89179321 141 MFQ--ILLDPEE 150
Cdd:COG4235  73 LLEraLALDPDN 84
TPR_1 pfam00515
Tetratricopeptide repeat;
77-110 1.33e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 1.33e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 89179321    77 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN 110
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_11 pfam13414
TPR repeat;
13-56 1.90e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.90e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 89179321    13 GNELFKCGDYGGALAAYTQALGLDatpQDQAVLHRNRAACHLKL 56
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLD---PDNPEAYYNLGLAYYKL 41
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 20-96 4.56e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 38.88  E-value: 4.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321   20 GDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKAIEKDGGDVKAL--------YRRSQALEKlG 91
Cdd:PRK02603  49 GEYAEALENYEEALKLEEDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALnniaviyhKRGEKAEEA-G 127


                 ....*
gi 89179321   92 RLDQA 96
Cdd:PRK02603 128 DQDEA 132
TPR_8 pfam13181
Tetratricopeptide repeat;
77-109 7.14e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.07  E-value: 7.14e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 89179321    77 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK 109
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 77-110 7.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 7.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 89179321     77 VKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN 110
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
25-121 7.90e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.74  E-value: 7.90e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 89179321  25 ALAAYTQALGLDATPQDQAVLHRNRA-ACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRC 103
Cdd:COG4785  20 SKAAILLAALLFAAVLALAIALADLAlALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQA 99

                        90
                ....*....|....*...
gi 89179321 104 VSLEPKNKvfqEALRNIG 121
Cdd:COG4785 100 LELDPDLA---EAYNNRG 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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