|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
124-593 |
1.23e-137 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 407.02 E-value: 1.23e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 124 ILGLYMLIIFDVIDHTFAALIIATTAVaILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRI 203
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLV-ILGLATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 204 SRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVTTspv 283
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 284 avAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDLMeerargkkppsqetldriallkgslpgkywl 363
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALA------------------------------- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 364 rpvegypetlaELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVadgaSLGWVTLLAAFLLIILDDKNDLNATLGII 443
Cdd:cd01116 204 -----------ELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPLGV----SLGWIALLGALLLLLLADKLDFEDVLSRV 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 444 QWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRslepqNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMAS 523
Cdd:cd01116 269 EWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVIL-----GRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLAS 343
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 524 NDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYLL 593
Cdd:cd01116 344 QLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVSLILATVYLL 413
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
120-596 |
8.72e-62 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 210.37 E-value: 8.72e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 120 AGLLILGLYMLIIFD--VIDHTFAALIIATTAVAILAIlehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLV 197
Cdd:COG1055 5 ALAIFVLTYLLIILEprGLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 198 VWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAI 277
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNIM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 278 vttspVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVldqnqldlmeerargkkppsqetldriallkgsl 357
Cdd:COG1055 160 -----IASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPA---------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 358 pgkywlrpvegypETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVAD------GASLGWVTLlaaflliild 431
Cdd:COG1055 201 -------------APDLEDDPKEAIKDRRLLRISLLVLALLLVGFVLHSFLGLPPaliallGAAVLLLLA---------- 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 432 dKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDrtvgFLRSLEPQNqIAVTTMVILWTTALLTIFIDNAAVT 511
Cdd:COG1055 258 -RVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAE----LLASLTGGN-LLLAALLILWLSAILSAVVDNVPLV 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 512 IFMLKFSIEMASNDDipLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGY 591
Cdd:COG1055 332 AALLPLIPDLGATGN--PEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKVGLPLTLLTLLIALLY 409
|
....*
gi 85724998 592 LLIAH 596
Cdd:COG1055 410 LLLLY 414
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
128-539 |
1.46e-49 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 175.19 E-value: 1.46e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 128 YMLIIFDVIDHTFAALIiattaVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGR 207
Cdd:pfam03600 1 YVLIITEKLPRDVVALL-----GAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 208 PWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAE 287
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNII-----IASAL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 288 GVDFAHFIIHMMPGVLAAMFVV-FGIIYVTHRKSIFVLDQNQLDLMEERARGKKppsqetldriallkgslpgkywlrpv 366
Cdd:pfam03600 151 GLSFGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRKRAIK-------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 367 egypetlaeleassrilDKPLLVRCCIALIFAFLCMLLHSIPKVADGASLGWVtllaaflliildDKNDLNATLGIIQWT 446
Cdd:pfam03600 205 -----------------DKLLLAISALVLALVILGFLLLSVLALAGALLLLLT------------GVLDPEEALKAVDWS 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 447 ILLFIAALFVLSEAVDQLGFFEWLGDrtvgflrSLEPQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDD 526
Cdd:pfam03600 256 TLLFFAGLFILVGALEKTGLADALAD-------ALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAG 328
|
410
....*....|....
gi 85724998 527 I-PLPPMFWALTFG 539
Cdd:pfam03600 329 LgDPDPLAWALAVG 342
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
151-588 |
5.84e-14 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 74.65 E-value: 5.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 151 AILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFL-VVWTYRISRGRPwpLIFFLSMLTAFLSAFLNSD 229
Cdd:PLN00136 43 AVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLKNAGMFKHLgRLLAWRSQGGRD--LLCRVCVVTALASALFTND 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 230 IMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVV 309
Cdd:PLN00136 121 TCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLV-----IAFNSKITFPKFLLGILPAMLAGMAVN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 310 FGIIYVTHRKSI-----FVLDQNQLDLMEErarGKKPPSQETL--DRIALLKGSLpgkywlrpvEGYPETLAELEASSRI 382
Cdd:PLN00136 196 MVMLLCMYWKDLdggaeLSVDGKQMEAVEE---GRSPASAKSTkqQSPALLQAGL---------NGDGNGDMSSMMSENI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 383 LDK-PLLVRCCIALIFAFLCMLLHSIP-----KVADGASLGWvTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFV 456
Cdd:PLN00136 264 STKhPWFMQCTEHRRKLFLKSFAYVVTvgmvvAYMVGLNMSW-TAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFI 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 457 LSEAVDQLGffewLGDRTVGFLRSLEPQNQ---IAVTTMVILwttaLLTIFIDNAAVTIFMlkfSIEMASNDDIPLPPMF 533
Cdd:PLN00136 343 TVSGFNKTG----LPGAIWNFMAPYSKVNSvggISVLSVIIL----LLSNLASNVPTVLLM---GDEVAAAAALISPAAV 411
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 85724998 534 ---W-ALTFGACFGGNGSLFGAVSNEII---ALIALQHGYKISFWHFFAIGFPLMLVTMVIG 588
Cdd:PLN00136 412 trsWlLLAWVSTVAGNLSLLGSAANLIVceqARRAPRNAYDLTFWQHIVFGVPSTLIVTAIG 473
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
123-544 |
3.14e-05 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 46.57 E-value: 3.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 123 LILGLYMLIIFDVIDHTFAALIIATTAVAILAIL---EHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVW 199
Cdd:TIGR00785 12 LLLAIFVAAIVGWILEPLPLPVTALLAIPIIAVLlgvLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 200 TYRISRGRPWPLIFFLSMLTAFLSAFL--NSDIMALSLTPITIRLC------EEMSLRT--SYVLVVMAIFADMGGALTP 269
Cdd:TIGR00785 92 LVGKMGGTTLGLGYFLVFLETLLAPMWpsNTARAGGILLPIIKSLLpllgskPEKSPRKigKYLMLGIAYSASIGSSGFL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 270 LGNPPNAIVT--TSPVAVAEgVDFAHFIIHMMPGVLAAMFVVFGIIYVTHR-KSIFVLDQNQLDLMEERARGKKPPSQET 346
Cdd:TIGR00785 172 TGSAPNALAAgiLSKILGIQ-ISWGDWFLAGLPLGIILLLLVPLLLYVLFPpELKLKDEVDLWAKEELEEMGPMSFREKA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 347 LDRIALLKGSLpgkyWlrpvegypetlaeleassrILDKPLLVRCCIALIFAFLCMLLHSIPKVADgaslgwvtllaafl 426
Cdd:TIGR00785 251 LLGIFLLALLL----W-------------------IFGGSLGINASVVALLAVVLMLFLGIVTWKD-------------- 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 427 liilddkndlnATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTTMVIlwtTALLTIFID 506
Cdd:TIGR00785 294 -----------IQKNKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLF---YIILYFFAS 359
|
410 420 430
....*....|....*....|....*....|....*...
gi 85724998 507 NAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGG 544
Cdd:TIGR00785 360 NTAHTAALVPIFFSVASAQGIPLELLALALALSASLMG 397
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
124-593 |
1.23e-137 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 407.02 E-value: 1.23e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 124 ILGLYMLIIFDVIDHTFAALIIATTAVaILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRI 203
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLV-ILGLATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 204 SRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVTTspv 283
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 284 avAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDLMeerargkkppsqetldriallkgslpgkywl 363
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALA------------------------------- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 364 rpvegypetlaELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVadgaSLGWVTLLAAFLLIILDDKNDLNATLGII 443
Cdd:cd01116 204 -----------ELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPLGV----SLGWIALLGALLLLLLADKLDFEDVLSRV 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 444 QWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRslepqNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMAS 523
Cdd:cd01116 269 EWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVIL-----GRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLAS 343
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 524 NDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYLL 593
Cdd:cd01116 344 QLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVSLILATVYLL 413
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
128-592 |
6.12e-72 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 236.76 E-value: 6.12e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 128 YMLIIFDVIDHTFAALIIATTAVAILAIlehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGR 207
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVV-----SPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 208 PWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAE 287
Cdd:cd00625 76 RRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPPVPLLLALAFAANIGGAATPIGNPPNLI-----IASLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 288 GVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQldlmeerargkkppsqetldriallkgslpgkywlrpve 367
Cdd:cd00625 151 GLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDK--------------------------------------- 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 368 gyPETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVAdgasLGWVTLLAAFLLIILDDKNDLNAtlgiIQWTI 447
Cdd:cd00625 192 --LTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLIA----LLGALLLLLLLVRGLDPEEVLKS----VDWGT 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 448 LLFIAALFVLSEAVDQLGFFEWLGDRTVGFLrslepQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMAsnddi 527
Cdd:cd00625 262 LLFFAGLFVLVGALESTGLLEWLAELLVALV-----GLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLA----- 331
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 85724998 528 PLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYL 592
Cdd:cd00625 332 PPEPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
120-596 |
8.72e-62 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 210.37 E-value: 8.72e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 120 AGLLILGLYMLIIFD--VIDHTFAALIIATTAVAILAIlehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLV 197
Cdd:COG1055 5 ALAIFVLTYLLIILEprGLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 198 VWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAI 277
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNIM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 278 vttspVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVldqnqldlmeerargkkppsqetldriallkgsl 357
Cdd:COG1055 160 -----IASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPA---------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 358 pgkywlrpvegypETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVAD------GASLGWVTLlaaflliild 431
Cdd:COG1055 201 -------------APDLEDDPKEAIKDRRLLRISLLVLALLLVGFVLHSFLGLPPaliallGAAVLLLLA---------- 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 432 dKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDrtvgFLRSLEPQNqIAVTTMVILWTTALLTIFIDNAAVT 511
Cdd:COG1055 258 -RVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAE----LLASLTGGN-LLLAALLILWLSAILSAVVDNVPLV 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 512 IFMLKFSIEMASNDDipLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGY 591
Cdd:COG1055 332 AALLPLIPDLGATGN--PEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKVGLPLTLLTLLIALLY 409
|
....*
gi 85724998 592 LLIAH 596
Cdd:COG1055 410 LLLLY 414
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
128-539 |
1.46e-49 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 175.19 E-value: 1.46e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 128 YMLIIFDVIDHTFAALIiattaVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGR 207
Cdd:pfam03600 1 YVLIITEKLPRDVVALL-----GAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 208 PWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAE 287
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNII-----IASAL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 288 GVDFAHFIIHMMPGVLAAMFVV-FGIIYVTHRKSIFVLDQNQLDLMEERARGKKppsqetldriallkgslpgkywlrpv 366
Cdd:pfam03600 151 GLSFGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRKRAIK-------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 367 egypetlaeleassrilDKPLLVRCCIALIFAFLCMLLHSIPKVADGASLGWVtllaaflliildDKNDLNATLGIIQWT 446
Cdd:pfam03600 205 -----------------DKLLLAISALVLALVILGFLLLSVLALAGALLLLLT------------GVLDPEEALKAVDWS 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 447 ILLFIAALFVLSEAVDQLGFFEWLGDrtvgflrSLEPQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDD 526
Cdd:pfam03600 256 TLLFFAGLFILVGALEKTGLADALAD-------ALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAG 328
|
410
....*....|....
gi 85724998 527 I-PLPPMFWALTFG 539
Cdd:pfam03600 329 LgDPDPLAWALAVG 342
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
151-588 |
1.50e-30 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 123.54 E-value: 1.50e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 151 AILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRiSRGRPWPLIFFLSMLTAFLSAFLNSDI 230
Cdd:cd01117 21 AALMLLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILV-KAGSPRRLLFLLVLLSGILSALLTNDT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 231 MALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVVF 310
Cdd:cd01117 100 ACLVFTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLL-----IASESGISFPFFLAAMAPLALLGLLLLL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 311 GIIYVTHRKSIfvldqnqldlmEERARGKKPPSQETLDRIALLKGSLPgkywlrpvegypetlaeleassrildkpllvr 390
Cdd:cd01117 175 ILLLVLFPGEL-----------KGLPLDKATKEEGVGARKLAVKLLVL-------------------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 391 cCIALIFAFLCML-LHSIPKVAdgaslgwVTLLAAFLLIILDDKNdlnaTLGIIQWTILLFIAALFVLSEAVDQLGFFEW 469
Cdd:cd01117 212 -ILLLLVAFLALLgVIPLWTAA-------LVAAVLLLLTRLKPRR----VLKKVDWGLLLFFAGLFILVGGFAQGLPLEG 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 470 LgdrtvgfLRSLEPQNQIAvttmVILWTTALLTIFIDNAAVTIFMLKFSIEmasnddipLPPMFW-ALTFGACFGGNGSL 548
Cdd:cd01117 280 L-------SRLLPLLDSVL----SLFLVSIGLSQLISNVPAVLLLLPFLPS--------ADEKDWlLLAAGSTIAGNLTL 340
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 85724998 549 FGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIG 588
Cdd:cd01117 341 LGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIG 380
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
178-594 |
9.84e-18 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 85.21 E-value: 9.84e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 178 FGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRT-----SY 252
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKrskfgSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 253 VLVVMAIFADMGGALTPLGNPPNAIVTT-SPVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDL 331
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGlLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 332 MEERARGKKPPSQEtldRIALLKGSLPGKYW-LRPVEGYPETLaeleassrildkpllvrccIALIFAFLCMLLHSIpkv 410
Cdd:COG0471 161 REELAELGPLSRRE---KIALAIFALTVLLWiTGSLHGIPIAV-------------------VALLGAVLLLLTGVL--- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 411 adgaslgwvtllaaflliildDKNDLNATlgiIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPqnqiAVT 490
Cdd:COG0471 216 ---------------------TWKDAYKS---IPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLGGLSP----LLL 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 491 TMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFG-----GNGSlfgavsneiiALIALQHG 565
Cdd:COG0471 268 LLLLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAASCAfllpvGTPP----------NAIVYGSG 337
|
410 420
....*....|....*....|....*....
gi 85724998 566 YkISFWHFFAIGFPLMLVTMVIGSGYLLI 594
Cdd:COG0471 338 Y-YKFKDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
151-588 |
5.84e-14 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 74.65 E-value: 5.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 151 AILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFL-VVWTYRISRGRPwpLIFFLSMLTAFLSAFLNSD 229
Cdd:PLN00136 43 AVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLKNAGMFKHLgRLLAWRSQGGRD--LLCRVCVVTALASALFTND 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 230 IMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVV 309
Cdd:PLN00136 121 TCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLV-----IAFNSKITFPKFLLGILPAMLAGMAVN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 310 FGIIYVTHRKSI-----FVLDQNQLDLMEErarGKKPPSQETL--DRIALLKGSLpgkywlrpvEGYPETLAELEASSRI 382
Cdd:PLN00136 196 MVMLLCMYWKDLdggaeLSVDGKQMEAVEE---GRSPASAKSTkqQSPALLQAGL---------NGDGNGDMSSMMSENI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 383 LDK-PLLVRCCIALIFAFLCMLLHSIP-----KVADGASLGWvTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFV 456
Cdd:PLN00136 264 STKhPWFMQCTEHRRKLFLKSFAYVVTvgmvvAYMVGLNMSW-TAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFI 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 457 LSEAVDQLGffewLGDRTVGFLRSLEPQNQ---IAVTTMVILwttaLLTIFIDNAAVTIFMlkfSIEMASNDDIPLPPMF 533
Cdd:PLN00136 343 TVSGFNKTG----LPGAIWNFMAPYSKVNSvggISVLSVIIL----LLSNLASNVPTVLLM---GDEVAAAAALISPAAV 411
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 85724998 534 ---W-ALTFGACFGGNGSLFGAVSNEII---ALIALQHGYKISFWHFFAIGFPLMLVTMVIG 588
Cdd:PLN00136 412 trsWlLLAWVSTVAGNLSLLGSAANLIVceqARRAPRNAYDLTFWQHIVFGVPSTLIVTAIG 473
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
177-593 |
2.93e-10 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 62.67 E-value: 2.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 177 LFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLV- 255
Cdd:cd01118 58 LIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPf 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 256 --VMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIfvldqnqldlme 333
Cdd:cd01118 138 lyACAFIADAASLPLPISNLVNIV-----TAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRAL------------ 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 334 erargkkPPSQETldriallkgslpgkywlrpvegypetlAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVADG 413
Cdd:cd01118 201 -------PKRLET---------------------------ASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVDILLIPP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 414 ASLGWVTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDrtvgFLRSLEPQNQIAvTTMV 493
Cdd:cd01118 247 SFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILAD----LLNWLVSQGLLA-AILG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 494 ILWTTALLTIFIDNAAVTIFMLkfsieMASNDDIPLPPMFWALTFGACFGGNGSLFGAVSNeIIALIAL-QHGYKISFWH 572
Cdd:cd01118 322 VGLLAAFLSNVMNNLPAVLIGA-----LALAAGHAPEALVYANLIGVDLGPKLTPIGSLAT-LLWLHVLrRKGIRVSWGY 395
|
410 420
....*....|....*....|.
gi 85724998 573 FFAIGFPLMLVTMVIGSGYLL 593
Cdd:cd01118 396 YLKVGLIVTPPVLVVTLAALI 416
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
140-595 |
3.89e-10 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 61.83 E-value: 3.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 140 FAALIIATTAVAI---LAILEHRPSMRAIVSFVNfEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLS 216
Cdd:cd01115 13 TEALPLDVTALLVpvlLVLLGVVPPKEAFSGFSD-PAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 217 MLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVttSPVAVAEGVDFAHFII 296
Cdd:cd01115 92 LVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVA--SGYLESLGGQGFSFFE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 297 HMMPGVLAAMFVVFgIIYVTHRKSIFVLdqnqldlmeerargkkppsqetldRIALLKGSLPGKYWLrpvegypetlael 376
Cdd:cd01115 170 FTPIGLPLLIIGLL-YLWFIFRLAVLII------------------------TIVLLAALAAITGLL------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 377 eassrildKPLLVRCCIALIFAFLCMLLhsipkvadgaslgwvtllaaflliildDKNDLNAtlgiIQWTILLFIAALFV 456
Cdd:cd01115 212 --------PVSVAIAIGAIVLVFGGVLL---------------------------TKEDYKS----IDWGIIFLFAGGIP 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 457 LSEAVDQLGFFEWLGDRTVGFLRSLEPqnqiAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWAL 536
Cdd:cd01115 253 LGKALESSGAAALIAEALISLLGGLPP----FAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAV 328
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 85724998 537 TFGA--CFggnGSLFGAVSNeiiaLIALQHGYkISFWHFFAIGFPLMLVTMVIGSGYLLIA 595
Cdd:cd01115 329 AIGAscAF---MLPVGTPPN----AIVLGPGG-YKFSDFAKVGLPLSILSLVVSVTMIPLI 381
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
443-602 |
1.69e-09 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 59.63 E-value: 1.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 443 IQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTtmvilWTTALLTIFIDNAAVTIFMLKFSIEMA 522
Cdd:pfam03600 37 IDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALM-----LATALLSAFLSNDGTVLIMIPIVLALA 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 523 SNDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIgsgYLLIAHSVLSWN 602
Cdd:pfam03600 112 RRLGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP---LLLIFRKLLPVR 188
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
443-594 |
2.06e-09 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 59.96 E-value: 2.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 443 IQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSlepQNQIAVTTMVIlwTTALLTIFIDNAAVTIFMLKFSIEMA 522
Cdd:cd00625 37 IDWETILLLFGMMILSAALEETGLFDRLAAKLARASKG---SRRLLLLLMLL--TAALSAFFSNDATAVLLTPIVLALLR 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 85724998 523 SNDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIAlialqHGYKISFWHFFAIGFPLMLVTMVIGSGYLLI 594
Cdd:cd00625 112 KLGLSPPVPLLLALAFAANIGGAATPIGNPPNLIIA-----SLSGLGFLDFLAFMAPPALGLLLLLLGLLYL 178
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
117-313 |
1.70e-08 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 56.87 E-value: 1.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 117 LVCAGLLILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFL 196
Cdd:cd00625 205 LKKFLLLALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWL 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 197 VVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLrtsyvLVVMAIFADMGGALTPLGNPPNA 276
Cdd:cd00625 285 AELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAPPEPA-----WLALALGSTLGGNLTLIGSLANL 359
|
170 180 190
....*....|....*....|....*....|....*..
gi 85724998 277 IVTTSPVAVAEGVDFAHFIIHMMPGVLAAMFVVFGII 313
Cdd:cd00625 360 IPLGAAENAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
122-315 |
2.70e-07 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 52.85 E-value: 2.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 122 LLILGLYMLIIFDVIDHTFAALIIATtAVAILAILehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTY 201
Cdd:COG0471 182 ALTVLLWITGSLHGIPIAVVALLGAV-LLLLTGVL----TWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 202 RISRGRPWPLIFF-LSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMgGALTPLGNPPNAIVTT 280
Cdd:COG0471 257 PLLGGLSPLLLLLlLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAASC-AFLLPVGTPPNAIVYG 335
|
170 180 190
....*....|....*....|....*....|....*
gi 85724998 281 SpvavaEGVDFAHFIIHMMPGVLAAMFVVFGIIYV 315
Cdd:COG0471 336 S-----GYYKFKDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
88-315 |
7.43e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 51.67 E-value: 7.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 88 AVISLESKRNSPISLHVVIDTNPMVTDMCLVCAGLLILGLymlIIFDVIDHTFAAL---IIATTAVAILAILeHRPSMRA 164
Cdd:COG1055 188 LVLYLLFRKELPAAPDLEDDPKEAIKDRRLLRISLLVLAL---LLVGFVLHSFLGLppaLIALLGAAVLLLL-ARVDVRE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 165 IVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNsdimALSLTPITIRLCE 244
Cdd:COG1055 264 VLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVD----NVPLVAALLPLIP 339
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 85724998 245 EMSLRTSYVLVVMA--IFADMGGALTPLGNPPNAIVttspVAVAEG----VDFAHFIIHMMPGVLAAMFVVFGIIYV 315
Cdd:COG1055 340 DLGATGNPEPLWLAlaLGATLGGNLTPIGSAANVIV----LGIAEKkgikISFGEFLKVGLPLTLLTLLIALLYLLL 412
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
123-544 |
3.14e-05 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 46.57 E-value: 3.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 123 LILGLYMLIIFDVIDHTFAALIIATTAVAILAIL---EHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVW 199
Cdd:TIGR00785 12 LLLAIFVAAIVGWILEPLPLPVTALLAIPIIAVLlgvLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 200 TYRISRGRPWPLIFFLSMLTAFLSAFL--NSDIMALSLTPITIRLC------EEMSLRT--SYVLVVMAIFADMGGALTP 269
Cdd:TIGR00785 92 LVGKMGGTTLGLGYFLVFLETLLAPMWpsNTARAGGILLPIIKSLLpllgskPEKSPRKigKYLMLGIAYSASIGSSGFL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 270 LGNPPNAIVT--TSPVAVAEgVDFAHFIIHMMPGVLAAMFVVFGIIYVTHR-KSIFVLDQNQLDLMEERARGKKPPSQET 346
Cdd:TIGR00785 172 TGSAPNALAAgiLSKILGIQ-ISWGDWFLAGLPLGIILLLLVPLLLYVLFPpELKLKDEVDLWAKEELEEMGPMSFREKA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 347 LDRIALLKGSLpgkyWlrpvegypetlaeleassrILDKPLLVRCCIALIFAFLCMLLHSIPKVADgaslgwvtllaafl 426
Cdd:TIGR00785 251 LLGIFLLALLL----W-------------------IFGGSLGINASVVALLAVVLMLFLGIVTWKD-------------- 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 427 liilddkndlnATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTTMVIlwtTALLTIFID 506
Cdd:TIGR00785 294 -----------IQKNKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLF---YIILYFFAS 359
|
410 420 430
....*....|....*....|....*....|....*...
gi 85724998 507 NAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGG 544
Cdd:TIGR00785 360 NTAHTAALVPIFFSVASAQGIPLELLALALALSASLMG 397
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
124-261 |
1.10e-04 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 44.61 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 124 ILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRI 203
Cdd:pfam03600 207 LLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGL 286
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 85724998 204 SrgRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFA 261
Cdd:pfam03600 287 S--GLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLAWALAVG 342
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
498-593 |
1.63e-03 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 41.13 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 498 TALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIAlqhgyKISFWHFFAIG 577
Cdd:PLN00136 110 TALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLVIAFNS-----KITFPKFLLGI 184
|
90
....*....|....*.
gi 85724998 578 FPLMLVTMVIGSGYLL 593
Cdd:PLN00136 185 LPAMLAGMAVNMVMLL 200
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
122-278 |
2.99e-03 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 40.26 E-value: 2.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85724998 122 LLILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFvNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTY 201
Cdd:cd01115 193 VLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSI-DWGIIFLFAGGIPLGKALESSGAAALIAEALI 271
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 85724998 202 RISRGRPWPLIFF-LSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMgGALTPLGNPPNAIV 278
Cdd:cd01115 272 SLLGGLPPFAILLlLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASC-AFMLPVGTPPNAIV 348
|
|
| |
