cytoplasmic FMR1-interacting protein 2 isoform a [Homo sapiens]
FragX_IP domain-containing protein( domain architecture ID 10532330)
FragX_IP domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | ||||||||||||
FragX_IP | pfam05994 | Cytoplasmic Fragile-X interacting family; This entry includes Cytoplasmic fragile X mental ... |
388-1221 | 0e+00 | ||||||||||||
Cytoplasmic Fragile-X interacting family; This entry includes Cytoplasmic fragile X mental retardation interacting proteins 1/2 (CYFIP1/2) from humans and their homologs, such as Sra-1 (specifically Rac1-associated protein 1) from Drosophila and PIROGI from Arabidopsis. CYFIP1/2 interact with FMRP (fragile X mental retardation protein) which is responsible for pathologic manifestations in the Fragile X Syndrome. CYFIP1 interacts with the small GTPase Rac1. CYFIP1 represses cap-dependent translation of mRNA by interacting with the initiation factor eIF4E. CYFIP1 and CYFIP2 are part of the Wiskott-Aldrich syndrome protein-family verprolin-homologous protein (WAVE) complex that regulates actin polymerization at synapses. Drosophila Sra-1 interacts with the Kette and Wasp. It is required for neuronal and bristle development in Drosophila. PIROGI is part of a WAVE complex that activates the ARP2/3 complex and is Involved in regulation of actin organization. : Pssm-ID: 461799 Cd Length: 842 Bit Score: 1424.75 E-value: 0e+00
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Name | Accession | Description | Interval | E-value | |||||||||||||||||
FragX_IP | pfam05994 | Cytoplasmic Fragile-X interacting family; This entry includes Cytoplasmic fragile X mental ... |
388-1221 | 0e+00 | |||||||||||||||||
Cytoplasmic Fragile-X interacting family; This entry includes Cytoplasmic fragile X mental retardation interacting proteins 1/2 (CYFIP1/2) from humans and their homologs, such as Sra-1 (specifically Rac1-associated protein 1) from Drosophila and PIROGI from Arabidopsis. CYFIP1/2 interact with FMRP (fragile X mental retardation protein) which is responsible for pathologic manifestations in the Fragile X Syndrome. CYFIP1 interacts with the small GTPase Rac1. CYFIP1 represses cap-dependent translation of mRNA by interacting with the initiation factor eIF4E. CYFIP1 and CYFIP2 are part of the Wiskott-Aldrich syndrome protein-family verprolin-homologous protein (WAVE) complex that regulates actin polymerization at synapses. Drosophila Sra-1 interacts with the Kette and Wasp. It is required for neuronal and bristle development in Drosophila. PIROGI is part of a WAVE complex that activates the ARP2/3 complex and is Involved in regulation of actin organization. Pssm-ID: 461799 Cd Length: 842 Bit Score: 1424.75 E-value: 0e+00
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PIR | PLN03099 | Protein PIR; Provisional |
5-1221 | 0e+00 | |||||||||||||||||
Protein PIR; Provisional Pssm-ID: 215574 [Multi-domain] Cd Length: 1232 Bit Score: 618.89 E-value: 0e+00
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Name | Accession | Description | Interval | E-value | |||||||||||||||||
FragX_IP | pfam05994 | Cytoplasmic Fragile-X interacting family; This entry includes Cytoplasmic fragile X mental ... |
388-1221 | 0e+00 | |||||||||||||||||
Cytoplasmic Fragile-X interacting family; This entry includes Cytoplasmic fragile X mental retardation interacting proteins 1/2 (CYFIP1/2) from humans and their homologs, such as Sra-1 (specifically Rac1-associated protein 1) from Drosophila and PIROGI from Arabidopsis. CYFIP1/2 interact with FMRP (fragile X mental retardation protein) which is responsible for pathologic manifestations in the Fragile X Syndrome. CYFIP1 interacts with the small GTPase Rac1. CYFIP1 represses cap-dependent translation of mRNA by interacting with the initiation factor eIF4E. CYFIP1 and CYFIP2 are part of the Wiskott-Aldrich syndrome protein-family verprolin-homologous protein (WAVE) complex that regulates actin polymerization at synapses. Drosophila Sra-1 interacts with the Kette and Wasp. It is required for neuronal and bristle development in Drosophila. PIROGI is part of a WAVE complex that activates the ARP2/3 complex and is Involved in regulation of actin organization. Pssm-ID: 461799 Cd Length: 842 Bit Score: 1424.75 E-value: 0e+00
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PIR | PLN03099 | Protein PIR; Provisional |
5-1221 | 0e+00 | |||||||||||||||||
Protein PIR; Provisional Pssm-ID: 215574 [Multi-domain] Cd Length: 1232 Bit Score: 618.89 E-value: 0e+00
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Blast search parameters | ||||
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