NDH-dependent cyclic electron flow 1 [Arabidopsis thaliana]
Protein Classification
aldose epimerase family protein( domain architecture ID 52393)
aldose epimerase family protein catalyzes the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| Aldose_epim super family | cl14648 | aldose 1-epimerase superfamily; Aldose 1-epimerases or mutarotases are key enzymes of ... |
52-203 | 1.52e-04 | ||||
aldose 1-epimerase superfamily; Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism; they catalyze the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate and the histidine as the active site acid to protonate the C-5 ring oxygen. The actual alignment was detected with superfamily member cd09020: Pssm-ID: 449342 Cd Length: 269 Bit Score: 42.60 E-value: 1.52e-04
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| Name | Accession | Description | Interval | E-value | ||||
| D-hex-6-P-epi_like | cd09020 | D-hexose-6-phosphate epimerase-like; D-Hexose-6-phosphate epimerase Ymr099c from Saccharomyces ... |
52-203 | 1.52e-04 | ||||
D-hexose-6-phosphate epimerase-like; D-Hexose-6-phosphate epimerase Ymr099c from Saccharomyces cerevisiae belongs to the large superfamily of aldose-1-epimerases. Its active site is very similar to the catalytic site of galactose mutarotase, the best studied member of the superfamily. It also contains the conserved glutamate and histidine residues that have been shown in galactose mutarotase to be critical for catalysis, the glutamate serving as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. In addition Ymr099c contains 2 conserved arginine residues which are involved in phosphate binding, and exhibits hexose-6-phosphate mutarotase activity on glucose-6-P, galactose-6-P and mannose-6-P. Pssm-ID: 185697 Cd Length: 269 Bit Score: 42.60 E-value: 1.52e-04
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| Name | Accession | Description | Interval | E-value | ||||
| D-hex-6-P-epi_like | cd09020 | D-hexose-6-phosphate epimerase-like; D-Hexose-6-phosphate epimerase Ymr099c from Saccharomyces ... |
52-203 | 1.52e-04 | ||||
D-hexose-6-phosphate epimerase-like; D-Hexose-6-phosphate epimerase Ymr099c from Saccharomyces cerevisiae belongs to the large superfamily of aldose-1-epimerases. Its active site is very similar to the catalytic site of galactose mutarotase, the best studied member of the superfamily. It also contains the conserved glutamate and histidine residues that have been shown in galactose mutarotase to be critical for catalysis, the glutamate serving as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. In addition Ymr099c contains 2 conserved arginine residues which are involved in phosphate binding, and exhibits hexose-6-phosphate mutarotase activity on glucose-6-P, galactose-6-P and mannose-6-P. Pssm-ID: 185697 Cd Length: 269 Bit Score: 42.60 E-value: 1.52e-04
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| Blast search parameters | ||||
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