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Conserved domains on  [gi|198278450|ref|NP_001030097|]
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palmitoyl thioesterase CPT1C [Rattus norvegicus]

Protein Classification

CPT_N and Carn_acyltransf domain-containing protein( domain architecture ID 11071383)

CPT_N and Carn_acyltransf domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Carn_acyltransf pfam00755
Choline/Carnitine o-acyltransferase;
174-752 0e+00

Choline/Carnitine o-acyltransferase;


:

Pssm-ID: 459926  Cd Length: 570  Bit Score: 650.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  174 QPVPGAQETVRKYLESMRPVLRDDAFDSVVALANDFLRLQAPRLQLYLQLKSWCASNYVSDWWEEFVYLRSRGSLV-NST 252
Cdd:pfam00755   1 LPVPPLEDTLDRYLESVKPLLTEEEYERTEKLVEEFLKGGGPKLQERLLERAKDKKNWLEDWWLDYAYLEYRDPLVlNSN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  253 YYM-----MDFLYvTPTPLQAARAGNAVHTLLLYRHLLNRQEIPPTLLMGMrPLCSAQYERMFNTTRIPGVEKDYLCHLQ 327
Cdd:pfam00755  81 PFFvfpddPDPLD-EPTNTQLKRAANLIYAALKFKRLLDRETLPPDVEGGV-PLCMSQYKRLFNTTRIPGKERDILQHFP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  328 DS----QHVAVFHQGRFFRVGTHSSNGLLSPRALEQQFQYILDDPSPACPLEEHLAALTAAPRSMWAQVRESVKTHA--- 400
Cdd:pfam00755 159 DSgvepRHIVVLRKGQFYKVDVLDSGRPLSPAELEAQLQRILDDASASNPPPPPVGVLTTDNRDVWAKAREELLKLDpgn 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  401 ATALETVEGAAFFVSLDSEpaglTRENPAASLDTYAHTLLTGQGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPVAGHL 480
Cdd:pfam00755 239 AESLEAIESALFVVCLDDA----SPEDKTELEGSHGGGSLGGDGTNRWFDKSLQLIVFKNGRAGFNGEHSPADGTPVLRL 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  481 WEFTLATECfqlgyATDGHCKGHPDPALPKPQRLQWDLPKQIQPSISLALRGAKTLSGNIDCHVFPFFHFGKSFIKGCHV 560
Cdd:pfam00755 315 NDYVLKSIF-----ENKPVSSSSASSLPPPPEKLEFELDPELKSAIEEAETRFDKLISDLDLRVLEFTDYGKNFIKKFKL 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  561 SSDSFIQLVLQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMENKERTDQQCLALFREAVDKHQALL 640
Cdd:pfam00755 390 SPDAFIQMALQLAYYRLHGKFAPTYESASTRKFRHGRTETIRSVTPESVAFVKAMLDPSASDEEKRELLRAAVKAHVKLT 469
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  641 KAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQ---VQSQQWLLSTSQIPVQQThlfdvhnypdyvsSGGGFGPAHDHGYG 717
Cdd:pfam00755 470 KEASTGQGVDRHLFGLKLVAKEGGLLPPLFSDpayKKSNHWVLSTSQLGSPAL-------------RGGGFGPVVPDGYG 536
                         570       580       590
                  ....*....|....*....|....*....|....*
gi 198278450  718 VSYIFMGENaISFHISSKQSSTETDSHRLGQHIED 752
Cdd:pfam00755 537 IGYNIQDDS-ISFSISSFKSSPETDTERFAKALEE 570
CPT_N super family cl24901
Carnitine O-palmitoyltransferase N-terminus; This domain is found at the N-terminus of ...
1-47 6.68e-13

Carnitine O-palmitoyltransferase N-terminus; This domain is found at the N-terminus of carnitine O-palmitoyltransferases. It functions as a regulatory domain and is linked to the catalytic domain (pfam00755) via two transmembrane regions.


The actual alignment was detected with superfamily member pfam16484:

Pssm-ID: 465132  Cd Length: 47  Bit Score: 63.43  E-value: 6.68e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 198278450    1 MAEAHQASSLLSSLSSDGAEVELSSSVWQEIYLSALRSWKRNLWRVW 47
Cdd:pfam16484   1 MAEAHQAVAFQFTVTPEGIDVQLSQEALKEIYLSGVRSWKKRLIRFK 47
 
Name Accession Description Interval E-value
Carn_acyltransf pfam00755
Choline/Carnitine o-acyltransferase;
174-752 0e+00

Choline/Carnitine o-acyltransferase;


Pssm-ID: 459926  Cd Length: 570  Bit Score: 650.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  174 QPVPGAQETVRKYLESMRPVLRDDAFDSVVALANDFLRLQAPRLQLYLQLKSWCASNYVSDWWEEFVYLRSRGSLV-NST 252
Cdd:pfam00755   1 LPVPPLEDTLDRYLESVKPLLTEEEYERTEKLVEEFLKGGGPKLQERLLERAKDKKNWLEDWWLDYAYLEYRDPLVlNSN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  253 YYM-----MDFLYvTPTPLQAARAGNAVHTLLLYRHLLNRQEIPPTLLMGMrPLCSAQYERMFNTTRIPGVEKDYLCHLQ 327
Cdd:pfam00755  81 PFFvfpddPDPLD-EPTNTQLKRAANLIYAALKFKRLLDRETLPPDVEGGV-PLCMSQYKRLFNTTRIPGKERDILQHFP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  328 DS----QHVAVFHQGRFFRVGTHSSNGLLSPRALEQQFQYILDDPSPACPLEEHLAALTAAPRSMWAQVRESVKTHA--- 400
Cdd:pfam00755 159 DSgvepRHIVVLRKGQFYKVDVLDSGRPLSPAELEAQLQRILDDASASNPPPPPVGVLTTDNRDVWAKAREELLKLDpgn 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  401 ATALETVEGAAFFVSLDSEpaglTRENPAASLDTYAHTLLTGQGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPVAGHL 480
Cdd:pfam00755 239 AESLEAIESALFVVCLDDA----SPEDKTELEGSHGGGSLGGDGTNRWFDKSLQLIVFKNGRAGFNGEHSPADGTPVLRL 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  481 WEFTLATECfqlgyATDGHCKGHPDPALPKPQRLQWDLPKQIQPSISLALRGAKTLSGNIDCHVFPFFHFGKSFIKGCHV 560
Cdd:pfam00755 315 NDYVLKSIF-----ENKPVSSSSASSLPPPPEKLEFELDPELKSAIEEAETRFDKLISDLDLRVLEFTDYGKNFIKKFKL 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  561 SSDSFIQLVLQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMENKERTDQQCLALFREAVDKHQALL 640
Cdd:pfam00755 390 SPDAFIQMALQLAYYRLHGKFAPTYESASTRKFRHGRTETIRSVTPESVAFVKAMLDPSASDEEKRELLRAAVKAHVKLT 469
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  641 KAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQ---VQSQQWLLSTSQIPVQQThlfdvhnypdyvsSGGGFGPAHDHGYG 717
Cdd:pfam00755 470 KEASTGQGVDRHLFGLKLVAKEGGLLPPLFSDpayKKSNHWVLSTSQLGSPAL-------------RGGGFGPVVPDGYG 536
                         570       580       590
                  ....*....|....*....|....*....|....*
gi 198278450  718 VSYIFMGENaISFHISSKQSSTETDSHRLGQHIED 752
Cdd:pfam00755 537 IGYNIQDDS-ISFSISSFKSSPETDTERFAKALEE 570
CPT_N pfam16484
Carnitine O-palmitoyltransferase N-terminus; This domain is found at the N-terminus of ...
1-47 6.68e-13

Carnitine O-palmitoyltransferase N-terminus; This domain is found at the N-terminus of carnitine O-palmitoyltransferases. It functions as a regulatory domain and is linked to the catalytic domain (pfam00755) via two transmembrane regions.


Pssm-ID: 465132  Cd Length: 47  Bit Score: 63.43  E-value: 6.68e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 198278450    1 MAEAHQASSLLSSLSSDGAEVELSSSVWQEIYLSALRSWKRNLWRVW 47
Cdd:pfam16484   1 MAEAHQAVAFQFTVTPEGIDVQLSQEALKEIYLSGVRSWKKRLIRFK 47
 
Name Accession Description Interval E-value
Carn_acyltransf pfam00755
Choline/Carnitine o-acyltransferase;
174-752 0e+00

Choline/Carnitine o-acyltransferase;


Pssm-ID: 459926  Cd Length: 570  Bit Score: 650.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  174 QPVPGAQETVRKYLESMRPVLRDDAFDSVVALANDFLRLQAPRLQLYLQLKSWCASNYVSDWWEEFVYLRSRGSLV-NST 252
Cdd:pfam00755   1 LPVPPLEDTLDRYLESVKPLLTEEEYERTEKLVEEFLKGGGPKLQERLLERAKDKKNWLEDWWLDYAYLEYRDPLVlNSN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  253 YYM-----MDFLYvTPTPLQAARAGNAVHTLLLYRHLLNRQEIPPTLLMGMrPLCSAQYERMFNTTRIPGVEKDYLCHLQ 327
Cdd:pfam00755  81 PFFvfpddPDPLD-EPTNTQLKRAANLIYAALKFKRLLDRETLPPDVEGGV-PLCMSQYKRLFNTTRIPGKERDILQHFP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  328 DS----QHVAVFHQGRFFRVGTHSSNGLLSPRALEQQFQYILDDPSPACPLEEHLAALTAAPRSMWAQVRESVKTHA--- 400
Cdd:pfam00755 159 DSgvepRHIVVLRKGQFYKVDVLDSGRPLSPAELEAQLQRILDDASASNPPPPPVGVLTTDNRDVWAKAREELLKLDpgn 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  401 ATALETVEGAAFFVSLDSEpaglTRENPAASLDTYAHTLLTGQGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPVAGHL 480
Cdd:pfam00755 239 AESLEAIESALFVVCLDDA----SPEDKTELEGSHGGGSLGGDGTNRWFDKSLQLIVFKNGRAGFNGEHSPADGTPVLRL 314
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  481 WEFTLATECfqlgyATDGHCKGHPDPALPKPQRLQWDLPKQIQPSISLALRGAKTLSGNIDCHVFPFFHFGKSFIKGCHV 560
Cdd:pfam00755 315 NDYVLKSIF-----ENKPVSSSSASSLPPPPEKLEFELDPELKSAIEEAETRFDKLISDLDLRVLEFTDYGKNFIKKFKL 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  561 SSDSFIQLVLQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMENKERTDQQCLALFREAVDKHQALL 640
Cdd:pfam00755 390 SPDAFIQMALQLAYYRLHGKFAPTYESASTRKFRHGRTETIRSVTPESVAFVKAMLDPSASDEEKRELLRAAVKAHVKLT 469
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198278450  641 KAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQ---VQSQQWLLSTSQIPVQQThlfdvhnypdyvsSGGGFGPAHDHGYG 717
Cdd:pfam00755 470 KEASTGQGVDRHLFGLKLVAKEGGLLPPLFSDpayKKSNHWVLSTSQLGSPAL-------------RGGGFGPVVPDGYG 536
                         570       580       590
                  ....*....|....*....|....*....|....*
gi 198278450  718 VSYIFMGENaISFHISSKQSSTETDSHRLGQHIED 752
Cdd:pfam00755 537 IGYNIQDDS-ISFSISSFKSSPETDTERFAKALEE 570
CPT_N pfam16484
Carnitine O-palmitoyltransferase N-terminus; This domain is found at the N-terminus of ...
1-47 6.68e-13

Carnitine O-palmitoyltransferase N-terminus; This domain is found at the N-terminus of carnitine O-palmitoyltransferases. It functions as a regulatory domain and is linked to the catalytic domain (pfam00755) via two transmembrane regions.


Pssm-ID: 465132  Cd Length: 47  Bit Score: 63.43  E-value: 6.68e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 198278450    1 MAEAHQASSLLSSLSSDGAEVELSSSVWQEIYLSALRSWKRNLWRVW 47
Cdd:pfam16484   1 MAEAHQAVAFQFTVTPEGIDVQLSQEALKEIYLSGVRSWKKRLIRFK 47
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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