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Conserved domains on  [gi|77817745|ref|NP_001030021|]
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GTPase, IMAP family member 1 [Rattus norvegicus]

Protein Classification

GTPase IMAP family protein( domain architecture ID 10111261)

GTPase immunity-associated protein (IMAP) family protein may function as regulator of lymphocyte survival and homeostasis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AIG1 cd01852
AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 ...
 28-229 2.05e-100

AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 (avrRpt2-induced gene 1) that appears to be involved in plant resistance to bacteria. The Arabidopsis disease resistance gene RPS2 is involved in recognition of bacterial pathogens carrying the avirulence gene avrRpt2. AIG1 exhibits RPS2- and avrRpt1-dependent induction early after infection with Pseudomonas syringae carrying avrRpt2. This subfamily also includes IAN-4 protein, which has GTP-binding activity and shares sequence homology with a novel family of putative GTP-binding proteins: the immuno-associated nucleotide (IAN) family. The evolutionary conservation of the IAN family provides a unique example of a plant pathogen response gene conserved in animals. The IAN/IMAP subfamily has been proposed to regulate apoptosis in vertebrates and angiosperm plants, particularly in relation to cancer, diabetes, and infections. The human IAN genes were renamed GIMAP (GTPase of the immunity associated proteins).


:

Pssm-ID: 206651 [Multi-domain]  Cd Length: 201  Bit Score: 292.90  E-value: 2.05e-100
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  28 LRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRRWAGRLVEVVDTPDIFSSETPrSDPGCVEAARCFVL 107
Cdd:cd01852   1 LRLVLVGKTGNGKSATGNTILGRKVFESKLSASGVTKTCQKESAVWDGRRVNVIDTPGLFDTSVS-PEQLSKEIIRCLSL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745 108 SAPGPHALLLVTQLGRFTTQDSQALAAVKRMFGKQVMARTVVVFTRKEDLAGDSLQDYVRCTDnRALRELVAECGDRVCA 187
Cdd:cd01852  80 SAPGPHAFLLVVPLGRFTEEEEQAVEELQELFGEKVLDHTIVLFTRGDDLEGGSLEDYLEDSC-EALKRLLEKCGGRYVA 158

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 77817745 188 LNNRATGSESEAQVEQLLDLVACLVREHRGTHYSNEVYELVQ 229
Cdd:cd01852 159 FNNKAKGREQEQQVKELLAKVEEMVRENGGKPYTNEMYEEAE 200
 
Name Accession Description Interval E-value
AIG1 cd01852
AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 ...
 28-229 2.05e-100

AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 (avrRpt2-induced gene 1) that appears to be involved in plant resistance to bacteria. The Arabidopsis disease resistance gene RPS2 is involved in recognition of bacterial pathogens carrying the avirulence gene avrRpt2. AIG1 exhibits RPS2- and avrRpt1-dependent induction early after infection with Pseudomonas syringae carrying avrRpt2. This subfamily also includes IAN-4 protein, which has GTP-binding activity and shares sequence homology with a novel family of putative GTP-binding proteins: the immuno-associated nucleotide (IAN) family. The evolutionary conservation of the IAN family provides a unique example of a plant pathogen response gene conserved in animals. The IAN/IMAP subfamily has been proposed to regulate apoptosis in vertebrates and angiosperm plants, particularly in relation to cancer, diabetes, and infections. The human IAN genes were renamed GIMAP (GTPase of the immunity associated proteins).


Pssm-ID: 206651 [Multi-domain]  Cd Length: 201  Bit Score: 292.90  E-value: 2.05e-100
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  28 LRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRRWAGRLVEVVDTPDIFSSETPrSDPGCVEAARCFVL 107
Cdd:cd01852   1 LRLVLVGKTGNGKSATGNTILGRKVFESKLSASGVTKTCQKESAVWDGRRVNVIDTPGLFDTSVS-PEQLSKEIIRCLSL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745 108 SAPGPHALLLVTQLGRFTTQDSQALAAVKRMFGKQVMARTVVVFTRKEDLAGDSLQDYVRCTDnRALRELVAECGDRVCA 187
Cdd:cd01852  80 SAPGPHAFLLVVPLGRFTEEEEQAVEELQELFGEKVLDHTIVLFTRGDDLEGGSLEDYLEDSC-EALKRLLEKCGGRYVA 158

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 77817745 188 LNNRATGSESEAQVEQLLDLVACLVREHRGTHYSNEVYELVQ 229
Cdd:cd01852 159 FNNKAKGREQEQQVKELLAKVEEMVRENGGKPYTNEMYEEAE 200
AIG1 pfam04548
AIG1 family; Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.
 28-233 2.42e-95

AIG1 family; Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.


Pssm-ID: 398307 [Multi-domain]  Cd Length: 200  Bit Score: 279.88  E-value: 2.42e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745    28 LRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRRWAGRLVEVVDTPDIFSSEtPRSDPGCVEAARCFVL 107
Cdd:pfam04548   1 LRIVLVGKTGNGKSATGNSILGRKAFESKLRAQGVTKTCQLVSRTWDGRIINVIDTPGLFDLS-VSNDFISKEIIRCLLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745   108 SAPGPHALLLVTQLGRFTTQDSQALAAVKRMFGKQVMARTVVVFTRKEDLAGDSLQDYVRCTDNRALRELVAEcgdrvca 187
Cdd:pfam04548  80 AEPGPHAVLLVLSLGRFTEEEEQALRTLQELFGSKILDYMIVVFTRKDDLEDDSLDDYLSDGCPEFLKEVLRT------- 152

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 77817745   188 lnnrATGSESEAQVEQLLDLVACLVREHRGTHYSNEVYELVQATRC 233
Cdd:pfam04548 153 ----ADGEEKEEQVQQLLALVEAIVKENGGKPYTNDLYEKIKEEGE 194
YeeP COG3596
Predicted GTPase [General function prediction only];
16-216 1.78e-07

Predicted GTPase [General function prediction only];


Pssm-ID: 442815 [Multi-domain]  Cd Length: 318  Bit Score: 51.69  E-value: 1.78e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  16 SEDDSRAPQEPHLRLILVGRTGTGKSATGNSILGQKcfLSRLGAV-PVTRSCTLAsrRW---AGRLVEVVDTPDIFSSET 91
Cdd:COG3596  28 EALERLLVELPPPVIALVGKTGAGKSSLINALFGAE--VAEVGVGrPCTREIQRY--RLesdGLPGLVLLDTPGLGEVNE 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  92 PRsdpgcvEAARCFVLSAPGPHALLLVTQLGRFTTQdsQALAAVKRMFGKQVMARTVVVFTRKEDL----AGDSLQDYVR 167
Cdd:COG3596 104 RD------REYRELRELLPEADLILWVVKADDRALA--TDEEFLQALRAQYPDPPVLVVLTQVDRLeperEWDPPYNWPS 175

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 77817745 168 CTDNRALRELVA-------ECGDRVCALNnrATGSESEAQVEQLLDLVACLVREHR 216
Cdd:COG3596 176 PPKEQNIRRALEaiaeqlgVPIDRVIPVS--AAEDRTGYGLEELVDALAEALPEAK 229
3a0901s02IAP34 TIGR00991
GTP-binding protein (Chloroplast Envelope Protein Translocase); [Transport and binding ...
 12-152 1.80e-06

GTP-binding protein (Chloroplast Envelope Protein Translocase); [Transport and binding proteins, Nucleosides, purines and pyrimidines]


Pssm-ID: 130064  Cd Length: 313  Bit Score: 48.74  E-value: 1.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745    12 GAYGSEDDSRapqephLRLILVGRTGTGKSATGNSILGQkcflsRLGAVPVTRS----CTLASRRWAGRLVEVVDTPDIF 87
Cdd:TIGR00991  29 GKLKEEDVSS------LTILVMGKGGVGKSSTVNSIIGE-----RIATVSAFQSeglrPMMVSRTRAGFTLNIIDTPGLI 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 77817745    88 ssETPRSDPGCVEAARCFVLSAPgPHALLLVTQLG--RFTTQDSQALAAVKRMFGKQVMARTVVVFT 152
Cdd:TIGR00991  98 --EGGYINDQAVNIIKRFLLGKT-IDVLLYVDRLDayRVDTLDGQVIRAITDSFGKDIWRKSLVVLT 161
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 11-83 1.19e-04

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 43.63  E-value: 1.19e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 77817745   11 EGAYGSEDDSRAPQEPHLRLILVGRTGTGKSATGNSILGqkcflsRLGAV----P-VTRSCTLASRRWAGRLVEVVDT 83
Cdd:PRK09518 259 EGSGFVAGDEKAGPKAVGVVAIVGRPNVGKSTLVNRILG------RREAVvedtPgVTRDRVSYDAEWAGTDFKLVDT 330
 
Name Accession Description Interval E-value
AIG1 cd01852
AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 ...
 28-229 2.05e-100

AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 (avrRpt2-induced gene 1) that appears to be involved in plant resistance to bacteria. The Arabidopsis disease resistance gene RPS2 is involved in recognition of bacterial pathogens carrying the avirulence gene avrRpt2. AIG1 exhibits RPS2- and avrRpt1-dependent induction early after infection with Pseudomonas syringae carrying avrRpt2. This subfamily also includes IAN-4 protein, which has GTP-binding activity and shares sequence homology with a novel family of putative GTP-binding proteins: the immuno-associated nucleotide (IAN) family. The evolutionary conservation of the IAN family provides a unique example of a plant pathogen response gene conserved in animals. The IAN/IMAP subfamily has been proposed to regulate apoptosis in vertebrates and angiosperm plants, particularly in relation to cancer, diabetes, and infections. The human IAN genes were renamed GIMAP (GTPase of the immunity associated proteins).


Pssm-ID: 206651 [Multi-domain]  Cd Length: 201  Bit Score: 292.90  E-value: 2.05e-100
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  28 LRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRRWAGRLVEVVDTPDIFSSETPrSDPGCVEAARCFVL 107
Cdd:cd01852   1 LRLVLVGKTGNGKSATGNTILGRKVFESKLSASGVTKTCQKESAVWDGRRVNVIDTPGLFDTSVS-PEQLSKEIIRCLSL 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745 108 SAPGPHALLLVTQLGRFTTQDSQALAAVKRMFGKQVMARTVVVFTRKEDLAGDSLQDYVRCTDnRALRELVAECGDRVCA 187
Cdd:cd01852  80 SAPGPHAFLLVVPLGRFTEEEEQAVEELQELFGEKVLDHTIVLFTRGDDLEGGSLEDYLEDSC-EALKRLLEKCGGRYVA 158

                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
gi 77817745 188 LNNRATGSESEAQVEQLLDLVACLVREHRGTHYSNEVYELVQ 229
Cdd:cd01852 159 FNNKAKGREQEQQVKELLAKVEEMVRENGGKPYTNEMYEEAE 200
AIG1 pfam04548
AIG1 family; Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.
 28-233 2.42e-95

AIG1 family; Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.


Pssm-ID: 398307 [Multi-domain]  Cd Length: 200  Bit Score: 279.88  E-value: 2.42e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745    28 LRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRRWAGRLVEVVDTPDIFSSEtPRSDPGCVEAARCFVL 107
Cdd:pfam04548   1 LRIVLVGKTGNGKSATGNSILGRKAFESKLRAQGVTKTCQLVSRTWDGRIINVIDTPGLFDLS-VSNDFISKEIIRCLLL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745   108 SAPGPHALLLVTQLGRFTTQDSQALAAVKRMFGKQVMARTVVVFTRKEDLAGDSLQDYVRCTDNRALRELVAEcgdrvca 187
Cdd:pfam04548  80 AEPGPHAVLLVLSLGRFTEEEEQALRTLQELFGSKILDYMIVVFTRKDDLEDDSLDDYLSDGCPEFLKEVLRT------- 152

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 77817745   188 lnnrATGSESEAQVEQLLDLVACLVREHRGTHYSNEVYELVQATRC 233
Cdd:pfam04548 153 ----ADGEEKEEQVQQLLALVEAIVKENGGKPYTNDLYEKIKEEGE 194
Toc34_like cd01853
Translocon at the Outer-envelope membrane of Chloroplasts 34-like (Toc34-like); The Toc34-like ...
 4-152 9.12e-13

Translocon at the Outer-envelope membrane of Chloroplasts 34-like (Toc34-like); The Toc34-like (Translocon at the Outer-envelope membrane of Chloroplasts) family contains several Toc proteins, including Toc34, Toc33, Toc120, Toc159, Toc86, Toc125, and Toc90. The Toc complex at the outer envelope membrane of chloroplasts is a molecular machine of ~500 kDa that contains a single Toc159 protein, four Toc75 molecules, and four or five copies of Toc34. Toc64 and Toc12 are associated with the translocon, but do not appear to be part of the core complex. The Toc translocon initiates the import of nuclear-encoded preproteins from the cytosol into the organelle. Toc34 and Toc159 are both GTPases, while Toc75 is a beta-barrel integral membrane protein. Toc159 is equally distributed between a soluble cytoplasmic form and a membrane-inserted form, suggesting that assembly of the Toc complex is dynamic. Toc34 and Toc75 act sequentially to mediate docking and insertion of Toc159 resulting in assembly of the functional translocon.


Pssm-ID: 206652  Cd Length: 248  Bit Score: 66.57  E-value: 9.12e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745   4 RKMVRDEEGAYGSEDDSRapqephLRLILVGRTGTGKSATGNSILG-QKCFLSRLGavPVTRSCTLASRRWAGRLVEVVD 82
Cdd:cd01853  14 QTKLHELEAKLKKELDFS------LTILVLGKTGVGKSSTINSIFGeRKVSVSAFQ--SETLRPREVSRTVDGFKLNIID 85

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 77817745  83 TPDIFSSETPRSDPGCVEAARCFVLSAPgPHALLLVTQLG--RFTTQDSQALAAVKRMFGKQVMARTVVVFT 152
Cdd:cd01853  86 TPGLLESQDQRVNRKILSIIKRFLKKKT-IDVVLYVDRLDmyRVDNLDVPLLRAITDSFGPSIWRNAIVVLT 156
Ras_like_GTPase cd00882
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like ...
 32-206 7.28e-08

Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.


Pssm-ID: 206648 [Multi-domain]  Cd Length: 161  Bit Score: 50.92  E-value: 7.28e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  32 LVGRTGTGKSATGNSILGQKcflsrLGAVPVTRSCTLASRRWA------GRLVEVVDTPDIFSSEtprsDPGCVEAARcf 105
Cdd:cd00882   2 VVGRGGVGKSSLLNALLGGE-----VGEVSDVPGTTRDPDVYVkeldkgKVKLVLVDTPGLDEFG----GLGREELAR-- 70

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745 106 vLSAPGPHALLLVTQLGRFTTQDSQALAAVKRMFGKQVmaRTVVVFTrKEDLAGDSLQDYVRCtdnraLRELVAECGDRV 185
Cdd:cd00882  71 -LLLRGADLILLVVDSTDRESEEDAKLLILRRLRKEGI--PIILVGN-KIDLLEEREVEELLR-----LEELAKILGVPV 141

                       170       180
                ....*....|....*....|.
gi 77817745 186 CALNNRaTGSESEAQVEQLLD 206
Cdd:cd00882 142 FEVSAK-TGEGVDELFEKLIE 161
YeeP COG3596
Predicted GTPase [General function prediction only];
16-216 1.78e-07

Predicted GTPase [General function prediction only];


Pssm-ID: 442815 [Multi-domain]  Cd Length: 318  Bit Score: 51.69  E-value: 1.78e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  16 SEDDSRAPQEPHLRLILVGRTGTGKSATGNSILGQKcfLSRLGAV-PVTRSCTLAsrRW---AGRLVEVVDTPDIFSSET 91
Cdd:COG3596  28 EALERLLVELPPPVIALVGKTGAGKSSLINALFGAE--VAEVGVGrPCTREIQRY--RLesdGLPGLVLLDTPGLGEVNE 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  92 PRsdpgcvEAARCFVLSAPGPHALLLVTQLGRFTTQdsQALAAVKRMFGKQVMARTVVVFTRKEDL----AGDSLQDYVR 167
Cdd:COG3596 104 RD------REYRELRELLPEADLILWVVKADDRALA--TDEEFLQALRAQYPDPPVLVVLTQVDRLeperEWDPPYNWPS 175

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 77817745 168 CTDNRALRELVA-------ECGDRVCALNnrATGSESEAQVEQLLDLVACLVREHR 216
Cdd:COG3596 176 PPKEQNIRRALEaiaeqlgVPIDRVIPVS--AAEDRTGYGLEELVDALAEALPEAK 229
3a0901s02IAP34 TIGR00991
GTP-binding protein (Chloroplast Envelope Protein Translocase); [Transport and binding ...
 12-152 1.80e-06

GTP-binding protein (Chloroplast Envelope Protein Translocase); [Transport and binding proteins, Nucleosides, purines and pyrimidines]


Pssm-ID: 130064  Cd Length: 313  Bit Score: 48.74  E-value: 1.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745    12 GAYGSEDDSRapqephLRLILVGRTGTGKSATGNSILGQkcflsRLGAVPVTRS----CTLASRRWAGRLVEVVDTPDIF 87
Cdd:TIGR00991  29 GKLKEEDVSS------LTILVMGKGGVGKSSTVNSIIGE-----RIATVSAFQSeglrPMMVSRTRAGFTLNIIDTPGLI 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 77817745    88 ssETPRSDPGCVEAARCFVLSAPgPHALLLVTQLG--RFTTQDSQALAAVKRMFGKQVMARTVVVFT 152
Cdd:TIGR00991  98 --EGGYINDQAVNIIKRFLLGKT-IDVLLYVDRLDayRVDTLDGQVIRAITDSFGKDIWRKSLVVLT 161
3a0901s04IAP86 TIGR00993
chloroplast protein import component Toc86/159, G and M domains; The long precursor of the 86K ...
 8-152 8.23e-05

chloroplast protein import component Toc86/159, G and M domains; The long precursor of the 86K protein originally described is proposed to have three domains. The N-terminal A-domain is acidic, repetitive, weakly conserved, readily removed by proteolysis during chloroplast isolation, and not required for protein translocation. The other domains are designated G (GTPase) and M (membrane anchor); this family includes most of the G domain and all of M. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273381 [Multi-domain]  Cd Length: 763  Bit Score: 44.17  E-value: 8.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745     8 RDEEGAYGSEDDSRAPQEPHLRLILVGRTGTGKSATGNSILG-QKCFLSRLGavPVTRSCTLASRRWAGRLVEVVDTPDI 86
Cdd:TIGR00993  99 AAKAMAEQLEAEGQDPLDFSLNILVLGKSGVGKSATINSIFGeVKFSTDAFG--MGTTSVQEIEGLVQGVKIRVIDTPGL 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745    87 FSSETPRS-DPGCVEAARCFVLSAPgPHALLLVTQLGrFTTQDSQ---ALAAVKRMFGKQVMARTVVVFT 152
Cdd:TIGR00993 177 KSSASDQSkNEKILSSVKKFIKKNP-PDIVLYVDRLD-MQTRDSNdlpLLRTITDVLGPSIWFNAIVTLT 244
PRK09518 PRK09518
bifunctional cytidylate kinase/GTPase Der; Reviewed
 11-83 1.19e-04

bifunctional cytidylate kinase/GTPase Der; Reviewed


Pssm-ID: 236546 [Multi-domain]  Cd Length: 712  Bit Score: 43.63  E-value: 1.19e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 77817745   11 EGAYGSEDDSRAPQEPHLRLILVGRTGTGKSATGNSILGqkcflsRLGAV----P-VTRSCTLASRRWAGRLVEVVDT 83
Cdd:PRK09518 259 EGSGFVAGDEKAGPKAVGVVAIVGRPNVGKSTLVNRILG------RREAVvedtPgVTRDRVSYDAEWAGTDFKLVDT 330
MMR_HSR1 pfam01926
50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete ...
 29-84 5.35e-04

50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.


Pssm-ID: 460387 [Multi-domain]  Cd Length: 113  Bit Score: 38.75  E-value: 5.35e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 77817745    29 RLILVGRTGTGKSATGNSILGQKcflSRLGAVP-VTRSCTLASRRWAGRLVEVVDTP 84
Cdd:pfam01926   1 RVALVGRPNVGKSTLINALTGAK---AIVSDYPgTTRDPNEGRLELKGKQIILVDTP 54
YfjP cd11383
YfjP GTPase; The Era (E. coli Ras-like protein)-like YfjP subfamily includes several ...
 32-139 1.99e-03

YfjP GTPase; The Era (E. coli Ras-like protein)-like YfjP subfamily includes several uncharacterized bacterial GTPases that are similar to Era. They generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain.


Pssm-ID: 206743 [Multi-domain]  Cd Length: 140  Bit Score: 37.70  E-value: 1.99e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77817745  32 LVGRTGTGKSATGNSILGqkcflSRLGAVPVTRSCTLASRR--WA--GRLVEVVDTPDIfsSETPRSDPGCVEAARCFVl 107
Cdd:cd11383   2 LMGKTGAGKSSLCNALFG-----TEVAAVGDRRPTTRAAQAyvWQtgGDGLVLLDLPGV--GERGRRDREYEELYRRLL- 73

                        90       100       110
                ....*....|....*....|....*....|..
gi 77817745 108 saPGPHALLLVTQlgrfttQDSQALAAVKRMF 139
Cdd:cd11383  74 --PEADLVLWLLD------ADDRALAADHDFY 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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