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Conserved domains on  [gi|85702101|ref|NP_001028957|]
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A-kinase anchor protein 14 [Mus musculus]

Protein Classification

AKAP28 domain-containing protein( domain architecture ID 10628022)

AKAP28 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AKAP28 pfam14469
28 kDa A-kinase anchor; 28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The ...
 408-527 3.17e-57

28 kDa A-kinase anchor; 28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella. Homologs of AKAP28 are present in all animals and in some, including mice the AKAP28-like domain are preceded by another uncharacterized domain


:

Pssm-ID: 464180  Cd Length: 121  Bit Score: 186.72  E-value: 3.17e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85702101   408 WLTHGEFTPEKGRKQIEKFVSTWEFQNRWVYYADFIEKKDLIHSYHYIYRVRWSAPTAVRPMARVSANALFTIKFNKSKP 487
Cdd:pfam14469   1 WMTIGEFTVENGRAQIEEYIKTWELSPSWLYHINFLEEEDLEFSTIYIYRVRWSIPTRRKPIPRATASVYFTIEVSKIKP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 85702101   488 ADMPVDVSYIFENSELLQRPGEIRFREQWLRDITETKHIL 527
Cdd:pfam14469  81 PHAPVMVTYVFEGQRLVHRPGSSRFREKWLKDIIESKLIL 120
 
Name Accession Description Interval E-value
AKAP28 pfam14469
28 kDa A-kinase anchor; 28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The ...
 408-527 3.17e-57

28 kDa A-kinase anchor; 28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella. Homologs of AKAP28 are present in all animals and in some, including mice the AKAP28-like domain are preceded by another uncharacterized domain


Pssm-ID: 464180  Cd Length: 121  Bit Score: 186.72  E-value: 3.17e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85702101   408 WLTHGEFTPEKGRKQIEKFVSTWEFQNRWVYYADFIEKKDLIHSYHYIYRVRWSAPTAVRPMARVSANALFTIKFNKSKP 487
Cdd:pfam14469   1 WMTIGEFTVENGRAQIEEYIKTWELSPSWLYHINFLEEEDLEFSTIYIYRVRWSIPTRRKPIPRATASVYFTIEVSKIKP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 85702101   488 ADMPVDVSYIFENSELLQRPGEIRFREQWLRDITETKHIL 527
Cdd:pfam14469  81 PHAPVMVTYVFEGQRLVHRPGSSRFREKWLKDIIESKLIL 120
 
Name Accession Description Interval E-value
AKAP28 pfam14469
28 kDa A-kinase anchor; 28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The ...
 408-527 3.17e-57

28 kDa A-kinase anchor; 28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella. Homologs of AKAP28 are present in all animals and in some, including mice the AKAP28-like domain are preceded by another uncharacterized domain


Pssm-ID: 464180  Cd Length: 121  Bit Score: 186.72  E-value: 3.17e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 85702101   408 WLTHGEFTPEKGRKQIEKFVSTWEFQNRWVYYADFIEKKDLIHSYHYIYRVRWSAPTAVRPMARVSANALFTIKFNKSKP 487
Cdd:pfam14469   1 WMTIGEFTVENGRAQIEEYIKTWELSPSWLYHINFLEEEDLEFSTIYIYRVRWSIPTRRKPIPRATASVYFTIEVSKIKP 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 85702101   488 ADMPVDVSYIFENSELLQRPGEIRFREQWLRDITETKHIL 527
Cdd:pfam14469  81 PHAPVMVTYVFEGQRLVHRPGSSRFREKWLKDIIESKLIL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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