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Conserved domains on  [gi|392895181|ref|NP_001022993|]
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Tetratricopeptide repeat protein 21 homolog [Caenorhabditis elegans]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 730-1022 8.34e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.17  E-value: 8.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  730 LLKVEATPGSYsLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLK 809
Cdd:COG2956     2 LLPVAAALGWY-FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  810 LA-NLLLKLRNFEKCEKVLRAPFERDPEpvgtetiqtYIQFLLLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltAA 888
Cdd:COG2956    81 ELaQDYLKAGLLDRAEELLEKLLELDPD---------DAEALRLLAEIYEQEGDWEKAIEVLERL-------------LK 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  889 LKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSIL 968
Cdd:COG2956   139 LGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRL 218

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 392895181  969 ADFYYIRSEAAHASTSYTTLLNTNPQHwHALSRVVELFCRNGEQNAAEKHLDRA 1022
Cdd:COG2956   219 AELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 514-801 6.74e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 6.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  514 LQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELiLDRGGKITDADDALVTGLNFNfklRETSLYHLIKSKTFK 593
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNL-YRRRGEYDRAIRIHQKLLERD---PDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  594 KRNENDEAIKTLKMALQIprkepsknlfqpkesaDTHKISVQLELIDTLQHMKRIQEAETTMTDALAEwagQPEQDQLVI 673
Cdd:COG2956    88 KAGLLDRAEELLEKLLEL----------------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL---GPENAHAYC 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  674 AQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEkKDKRMFAACYRELLKVE-ATPGSYSLLGDAFMKVQE 752
Cdd:COG2956   149 ELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ-GDYEEAIAALERALEQDpDYLPALPRLAELYEKLGD 227

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 392895181  753 PEDAINFYEQALKMQSKDVQLaEKIGEAYVMAHLYSKAVNFYESSMNIY 801
Cdd:COG2956   228 PEEALELLRKALELDPSDDLL-LALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1164-1323 9.16e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 9.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1164 NVGAVFGVARGHVLLKQVQKAKTVLKMVngrvwnFDDSDYLEKCWLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFE 1243
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERL------LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1244 LYGYMREKEQKYVEAYKMYEKAFmatkERNPGFG---YKLAFTYLKAKRLFACIETCQKVLDLNPQYPKI--------KK 1312
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERAL----EQDPDYLpalPRLAELYEKLGDPEEALELLRKALELDPSDDLLlaladlleRK 258

                         170
                  ....*....|.
gi 392895181 1313 EIMDKAKALIR 1323
Cdd:COG2956   259 EGLEAALALLE 269
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 730-1022 8.34e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.17  E-value: 8.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  730 LLKVEATPGSYsLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLK 809
Cdd:COG2956     2 LLPVAAALGWY-FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  810 LA-NLLLKLRNFEKCEKVLRAPFERDPEpvgtetiqtYIQFLLLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltAA 888
Cdd:COG2956    81 ELaQDYLKAGLLDRAEELLEKLLELDPD---------DAEALRLLAEIYEQEGDWEKAIEVLERL-------------LK 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  889 LKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSIL 968
Cdd:COG2956   139 LGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRL 218

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 392895181  969 ADFYYIRSEAAHASTSYTTLLNTNPQHwHALSRVVELFCRNGEQNAAEKHLDRA 1022
Cdd:COG2956   219 AELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 514-801 6.74e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 6.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  514 LQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELiLDRGGKITDADDALVTGLNFNfklRETSLYHLIKSKTFK 593
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNL-YRRRGEYDRAIRIHQKLLERD---PDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  594 KRNENDEAIKTLKMALQIprkepsknlfqpkesaDTHKISVQLELIDTLQHMKRIQEAETTMTDALAEwagQPEQDQLVI 673
Cdd:COG2956    88 KAGLLDRAEELLEKLLEL----------------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL---GPENAHAYC 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  674 AQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEkKDKRMFAACYRELLKVE-ATPGSYSLLGDAFMKVQE 752
Cdd:COG2956   149 ELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ-GDYEEAIAALERALEQDpDYLPALPRLAELYEKLGD 227

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 392895181  753 PEDAINFYEQALKMQSKDVQLaEKIGEAYVMAHLYSKAVNFYESSMNIY 801
Cdd:COG2956   228 PEEALELLRKALELDPSDDLL-LALADLLERKEGLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 506-1324 1.28e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 75.89  E-value: 1.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   506 APGLAHCTLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELILDRGgKITDADDAL--VTGLNFNFklretSL 583
Cdd:TIGR02917  155 DPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLG-NIELALAAYrkAIALRPNN-----IA 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   584 YHLIKSKTFKKRNENDEAIKTLKMALQIPRKEPSknlfqpkesadTHKISVQLELidtlqHMKRIQEAETTMTDALAEWA 663
Cdd:TIGR02917  229 VLLALATILIEAGEFEEAEKHADALLKKAPNSPL-----------AHYLKALVDF-----QKKNYEDARETLQDALKSAP 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   664 GQPEQDQLV----IAQAQLYLTKGHVERALgilkKIQPgqsNFHLSRIKMAEIYLEEKKDKRMFAACYRELLKVEATPGS 739
Cdd:TIGR02917  293 EYLPALLLAgaseYQLGNLEQAYQYLNQIL----KYAP---NSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAA 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   740 YSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVnfyessmniykdknmrlklanlllklrn 819
Cdd:TIGR02917  366 LSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAI---------------------------- 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   820 fekceKVLRAPFERDPEPVGTEtiqtyiqflLLLAECHemMDNvpeamNDFEKAKSLHSRIQDKTltaalkKEGARICNL 899
Cdd:TIGR02917  418 -----ADLETAAQLDPELGRAD---------LLLILSY--LRS-----GQFDKALAAAKKLEKKQ------PDNASLHNL 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   900 QAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAA 979
Cdd:TIGR02917  471 LGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEE 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   980 HASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVTesgYNVCRGRFEWYTGDQNEALRYYS-- 1057
Cdd:TIGR02917  551 EAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPE---AWLMLGRAQLAAGDLNKAVSSFKkl 627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  1058 ---------------------RTKDSAAGWREKALYymidicLNPDN--------EIIIDENSVEnPETTIVEEASEQQK 1108
Cdd:TIGR02917  628 lalqpdsalalllladayavmKNYAKAITSLKRALE------LKPDNteaqiglaQLLLAAKRTE-SAKKIAKSLQKQHP 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  1109 LAKYYLDLLGKLpttdrfllaqnfirmHTTDKSAIQAAldefnrMAFNADRSQVTNVGAVFGVARGHVLLKQVQKAktvL 1188
Cdd:TIGR02917  701 KAALGFELEGDL---------------YLRQKDYPAAI------QAYRKALKRAPSSQNAIKLHRALLASGNTAEA---V 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  1189 KMVNGRVWNFDDSDYLEkcwLMLADIYINQNKNDQAVT-FLDLVFKYNCNCLKAFELygYMREKEQKYVEAYKMYEKAFm 1267
Cdd:TIGR02917  757 KTLEAWLKTHPNDAVLR---TALAELYLAQKDYDKAIKhYQTVVKKAPDNAVVLNNL--AWLYLELKDPRALEYAERAL- 830

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 392895181  1268 ATKERNPGFGYKLAFTYLKAKRLFACIETCQKVLDLNPQYPKIKKEImdkAKALIRT 1324
Cdd:TIGR02917  831 KLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHL---ALALLAT 884
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1164-1323 9.16e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 9.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1164 NVGAVFGVARGHVLLKQVQKAKTVLKMVngrvwnFDDSDYLEKCWLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFE 1243
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERL------LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1244 LYGYMREKEQKYVEAYKMYEKAFmatkERNPGFG---YKLAFTYLKAKRLFACIETCQKVLDLNPQYPKI--------KK 1312
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERAL----EQDPDYLpalPRLAELYEKLGDPEEALELLRKALELDPSDDLLlaladlleRK 258

                         170
                  ....*....|.
gi 392895181 1313 EIMDKAKALIR 1323
Cdd:COG2956   259 EGLEAALALLE 269
TPR_12 pfam13424
Tetratricopeptide repeat;
739-803 2.82e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.82e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392895181   739 SYSLLGDAFMKVQEPEDAINFYEQALKMQSK--------DVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKD 803
Cdd:pfam13424    5 ALNNLAAVLRRLGRYDEALELLEKALEIARRllgpdhplTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 730-1022 8.34e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.17  E-value: 8.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  730 LLKVEATPGSYsLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLK 809
Cdd:COG2956     2 LLPVAAALGWY-FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  810 LA-NLLLKLRNFEKCEKVLRAPFERDPEpvgtetiqtYIQFLLLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltAA 888
Cdd:COG2956    81 ELaQDYLKAGLLDRAEELLEKLLELDPD---------DAEALRLLAEIYEQEGDWEKAIEVLERL-------------LK 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  889 LKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSIL 968
Cdd:COG2956   139 LGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRL 218

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 392895181  969 ADFYYIRSEAAHASTSYTTLLNTNPQHwHALSRVVELFCRNGEQNAAEKHLDRA 1022
Cdd:COG2956   219 AELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 514-801 6.74e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 6.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  514 LQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELiLDRGGKITDADDALVTGLNFNfklRETSLYHLIKSKTFK 593
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNL-YRRRGEYDRAIRIHQKLLERD---PDRAEALLELAQDYL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  594 KRNENDEAIKTLKMALQIprkepsknlfqpkesaDTHKISVQLELIDTLQHMKRIQEAETTMTDALAEwagQPEQDQLVI 673
Cdd:COG2956    88 KAGLLDRAEELLEKLLEL----------------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL---GPENAHAYC 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  674 AQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEkKDKRMFAACYRELLKVE-ATPGSYSLLGDAFMKVQE 752
Cdd:COG2956   149 ELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ-GDYEEAIAALERALEQDpDYLPALPRLAELYEKLGD 227

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 392895181  753 PEDAINFYEQALKMQSKDVQLaEKIGEAYVMAHLYSKAVNFYESSMNIY 801
Cdd:COG2956   228 PEEALELLRKALELDPSDDLL-LALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 580-834 2.60e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.77  E-value: 2.60e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  580 ETSLYHLIKSKTFKKRNENDEAIKTLKMALQIprkepsknlfqpkesaDTHKISVQLELIDTLQHMKRIQEAETTMTDAL 659
Cdd:COG2956    40 ETVEAHLALGNLYRRRGEYDRAIRIHQKLLER----------------DPDRAEALLELAQDYLKAGLLDRAEELLEKLL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  660 AEwagQPEQDQLVIAQAQLYLTKGHVERALGILKK---IQPGQSNFHLsriKMAEIYLEEKKDKRMFAAcYRELLKVEAT 736
Cdd:COG2956   104 EL---DPDDAEALRLLAEIYEQEGDWEKAIEVLERllkLGPENAHAYC---ELAELYLEQGDYDEAIEA-LEKALKLDPD 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  737 -PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDKNMRLKLANLLL 815
Cdd:COG2956   177 cARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLE 256

                         250
                  ....*....|....*....
gi 392895181  816 KLRNFEKCEKVLRAPFERD 834
Cdd:COG2956   257 RKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 851-1058 6.42e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 6.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  851 LLLAECHEMMDNVPEAMNDFEKAKSLHSriqdKTLTAALKKegaricnlqAELLYRRREFSQAVDICKQALAYHETDLKA 930
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDP----ETVEAHLAL---------GNLYRRRGEYDRAIRIHQKLLERDPDRAEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  931 NLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNG 1010
Cdd:COG2956    79 LLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 392895181 1011 EQNAAEKHLDRAKEVNPRCVtesGYNVCRGRFEWYTGDQNEALRYYSR 1058
Cdd:COG2956   159 DYDEAIEALEKALKLDPDCA---RALLLLAELYLEQGDYEEAIAALER 203
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 506-1324 1.28e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 75.89  E-value: 1.28e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   506 APGLAHCTLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELILDRGgKITDADDAL--VTGLNFNFklretSL 583
Cdd:TIGR02917  155 DPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLG-NIELALAAYrkAIALRPNN-----IA 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   584 YHLIKSKTFKKRNENDEAIKTLKMALQIPRKEPSknlfqpkesadTHKISVQLELidtlqHMKRIQEAETTMTDALAEWA 663
Cdd:TIGR02917  229 VLLALATILIEAGEFEEAEKHADALLKKAPNSPL-----------AHYLKALVDF-----QKKNYEDARETLQDALKSAP 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   664 GQPEQDQLV----IAQAQLYLTKGHVERALgilkKIQPgqsNFHLSRIKMAEIYLEEKKDKRMFAACYRELLKVEATPGS 739
Cdd:TIGR02917  293 EYLPALLLAgaseYQLGNLEQAYQYLNQIL----KYAP---NSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAA 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   740 YSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVnfyessmniykdknmrlklanlllklrn 819
Cdd:TIGR02917  366 LSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAI---------------------------- 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   820 fekceKVLRAPFERDPEPVGTEtiqtyiqflLLLAECHemMDNvpeamNDFEKAKSLHSRIQDKTltaalkKEGARICNL 899
Cdd:TIGR02917  418 -----ADLETAAQLDPELGRAD---------LLLILSY--LRS-----GQFDKALAAAKKLEKKQ------PDNASLHNL 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   900 QAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAA 979
Cdd:TIGR02917  471 LGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEE 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   980 HASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVTesgYNVCRGRFEWYTGDQNEALRYYS-- 1057
Cdd:TIGR02917  551 EAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPE---AWLMLGRAQLAAGDLNKAVSSFKkl 627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  1058 ---------------------RTKDSAAGWREKALYymidicLNPDN--------EIIIDENSVEnPETTIVEEASEQQK 1108
Cdd:TIGR02917  628 lalqpdsalalllladayavmKNYAKAITSLKRALE------LKPDNteaqiglaQLLLAAKRTE-SAKKIAKSLQKQHP 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  1109 LAKYYLDLLGKLpttdrfllaqnfirmHTTDKSAIQAAldefnrMAFNADRSQVTNVGAVFGVARGHVLLKQVQKAktvL 1188
Cdd:TIGR02917  701 KAALGFELEGDL---------------YLRQKDYPAAI------QAYRKALKRAPSSQNAIKLHRALLASGNTAEA---V 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  1189 KMVNGRVWNFDDSDYLEkcwLMLADIYINQNKNDQAVT-FLDLVFKYNCNCLKAFELygYMREKEQKYVEAYKMYEKAFm 1267
Cdd:TIGR02917  757 KTLEAWLKTHPNDAVLR---TALAELYLAQKDYDKAIKhYQTVVKKAPDNAVVLNNL--AWLYLELKDPRALEYAERAL- 830

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 392895181  1268 ATKERNPGFGYKLAFTYLKAKRLFACIETCQKVLDLNPQYPKIKKEImdkAKALIRT 1324
Cdd:TIGR02917  831 KLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHL---ALALLAT 884
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 647-924 1.42e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.45  E-value: 1.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  647 RIQEAETTMTDALAEwagQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEKKDKRmfA-A 725
Cdd:COG2956    23 QPDKAIDLLEEALEL---DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR--AeE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  726 CYRELLKVEAT-PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKDK 804
Cdd:COG2956    98 LLEKLLELDPDdAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  805 -NMRLKLANLLLKLRNFEKCEKVLRAPFERDPEpvgtetiqtYIQFLLLLAECHEMMDNVPEAMNDFEKAKSLHSRIQDK 883
Cdd:COG2956   178 aRALLLLAELYLEQGDYEEAIAALERALEQDPD---------YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 392895181  884 tltaalkkegaricNLQAELLYRRREFSQAVDICKQALAYH 924
Cdd:COG2956   249 --------------LALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 854-1028 9.63e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 9.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  854 AECHEMMDNVPEAMNDFEKAKSLHSRIqdktltAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLL 933
Cdd:COG2956    42 VEAHLALGNLYRRRGEYDRAIRIHQKL------LERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRL 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  934 LSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQN 1013
Cdd:COG2956   116 LAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYE 195

                         170
                  ....*....|....*
gi 392895181 1014 AAEKHLDRAKEVNPR 1028
Cdd:COG2956   196 EAIAALERALEQDPD 210
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 900-1028 1.20e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.59  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  900 QAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAA 979
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 392895181  980 HASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPR 1028
Cdd:COG4783    90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 667-803 9.64e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.20  E-value: 9.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  667 EQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLeEKKDKRMFAACYRELLKVEAT-PGSYSLLGD 745
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILL-QLGDLDEAIVLLHEALELDPDePEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 392895181  746 AFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKD 803
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
888-1076 7.55e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.01  E-value: 7.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  888 ALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSI 967
Cdd:COG0457     2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  968 LADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVtESGYNvcRGRFEWYTG 1047
Cdd:COG0457    82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDA-DALYN--LGIALEKLG 158

                         170       180
                  ....*....|....*....|....*....
gi 392895181 1048 DQNEALRYYSRTKDSAAGWREKALYYMID 1076
Cdd:COG0457   159 RYEEALELLEKLEAAALAALLAAALGEAA 187
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1164-1323 9.16e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 9.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1164 NVGAVFGVARGHVLLKQVQKAKTVLKMVngrvwnFDDSDYLEKCWLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFE 1243
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERL------LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALL 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1244 LYGYMREKEQKYVEAYKMYEKAFmatkERNPGFG---YKLAFTYLKAKRLFACIETCQKVLDLNPQYPKI--------KK 1312
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERAL----EQDPDYLpalPRLAELYEKLGDPEEALELLRKALELDPSDDLLlaladlleRK 258

                         170
                  ....*....|.
gi 392895181 1313 EIMDKAKALIR 1323
Cdd:COG2956   259 EGLEAALALLE 269
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 676-1027 9.68e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.63  E-value: 9.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   676 AQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEKKDKRMFAacyrELLKVEATPGS-----YSLLGDAFMKV 750
Cdd:TIGR02917   63 GKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLD----ELPGKTLLDDEgaaelLALRGLAYLGL 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   751 QEPEDAINFYEQALKMQSKdvQLAEKIGEAYVMAhlyskAVNFYESSMNIykdknmrlklanlllklrnfekCEKVLRAp 830
Cdd:TIGR02917  139 GQLELAQKSYEQALAIDPR--SLYAKLGLAQLAL-----AENRFDEARAL----------------------IDEVLTA- 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   831 ferDPEPVGTetiqtyiqfLLLLAECHEMMDNVPEAMNDFEKAKSLH------------SRIQ-------DKTLTAALKK 891
Cdd:TIGR02917  189 ---DPGNVDA---------LLLKGDLLLSLGNIELALAAYRKAIALRpnniavllalatILIEagefeeaEKHADALLKK 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   892 -----EGARicnLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANS 966
Cdd:TIGR02917  257 apnspLAHY---LKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARR 333

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 392895181   967 ILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNP 1027
Cdd:TIGR02917  334 LLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDP 394
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 496-1027 8.78e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 8.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   496 AKTLQMIYDVAPGLAHCTLQLARnSYLCSN-TNAAEKWIEKVLDKDDSLADAHILRAELILDRGgkitDADDALVTGLNF 574
Cdd:TIGR02917  383 AEYLAKATELDPENAAARTQLGI-SKLSQGdPSEAIADLETAAQLDPELGRADLLLILSYLRSG----QFDKALAAAKKL 457

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   575 NFKLRETSLYHLIKSKTFKKRNENDEAIKTLKMALQIprkEPSknlfQPKESADTHKISVQLELIDtlqhmKRIQEAEtt 654
Cdd:TIGR02917  458 EKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSI---EPD----FFPAAANLARIDIQEGNPD-----DAIQRFE-- 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   655 mtDALAEwagQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEKKDKRMFAACYRELLKVE 734
Cdd:TIGR02917  524 --KVLTI---DPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAP 598

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   735 ATPGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKD-KNMRLKLANL 813
Cdd:TIGR02917  599 DSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDnTEAQIGLAQL 678

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   814 LLKLRNFEKCEKVLRAPFERDPE-PVGTEtiqtyiqfllLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltaaLKKE 892
Cdd:TIGR02917  679 LLAAKRTESAKKIAKSLQKQHPKaALGFE----------LEGDLYLRQKDYPAAIQAYRKA---------------LKRA 733

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181   893 -GARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILAdF 971
Cdd:TIGR02917  734 pSSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLA-W 812

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 392895181   972 YYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNP 1027
Cdd:TIGR02917  813 LYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAP 868
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 847-1026 2.71e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.92  E-value: 2.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  847 IQFLLLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHET 926
Cdd:COG3914    78 AALLELAALLLQALGRYEEALALYRRA-------------LALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  927 DLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELF 1006
Cdd:COG3914   145 FAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL 224

                         170       180
                  ....*....|....*....|
gi 392895181 1007 CRNGEQNAAEKHLDRAKEVN 1026
Cdd:COG3914   225 RQACDWEVYDRFEELLAALA 244
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 706-877 3.66e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 3.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  706 RIKMAEIYLEEKKDKRMFAAcYRELLKVEAT-PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMA 784
Cdd:COG4783     7 LYALAQALLLAGDYDEAEAL-LEKALELDPDnPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  785 HLYSKAVNFYESSMniykdknmrlklanlllklrnfekcekvlrapfERDPEpvgtetiqtYIQFLLLLAECHEMMDNVP 864
Cdd:COG4783    86 GDYDEALALLEKAL---------------------------------KLDPE---------HPEAYLRLARAYRALGRPD 123

                         170
                  ....*....|...
gi 392895181  865 EAMNDFEKAKSLH 877
Cdd:COG4783   124 EAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
701-935 8.82e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 8.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  701 NFHLSRIKMAEIYLEEKKDKRMfAACYRELLKVEAT-PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGE 779
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEA-IEDYEKALELDPDdAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  780 AYVMAHLYSKAVNFYESSMNIykdknmrlklanlllklrnfekcekvlrapferDPEpvgtetiqtYIQFLLLLAECHEM 859
Cdd:COG0457    85 ALQALGRYEEALEDYDKALEL---------------------------------DPD---------DAEALYNLGLALLE 122

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392895181  860 MDNVPEAMNDFEKAkslhsriqdktltAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLS 935
Cdd:COG0457   123 LGRYDEAIEAYERA-------------LELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGE 185
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1208-1314 1.52e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 1.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1208 WLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFELYGYMREKEQKYVEAYKMYEKAfMATKERNPGFGYKLAFTYLKA 1287
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEA-LELDPDEPEARLNLGLALLKA 85

                          90       100
                  ....*....|....*....|....*..
gi 392895181 1288 KRLFACIETCQKVLDLNPQYPKIKKEI 1314
Cdd:COG4783    86 GDYDEALALLEKALKLDPEHPEAYLRL 112
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1208-1307 1.61e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 1.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1208 WLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFELYGYMREKEQKYVEAYKMYEKAfMATKERNPGFGYKLAFTYLKA 1287
Cdd:COG4783    41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKA-LKLDPEHPEAYLRLARAYRAL 119

                          90       100
                  ....*....|....*....|
gi 392895181 1288 KRLFACIETCQKVLDLNPQY 1307
Cdd:COG4783   120 GRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 631-770 1.91e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  631 KISVQLELIDTLQHMKRIQEAETTMTDALAEwagQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMA 710
Cdd:COG4783     3 CAEALYALAQALLLAGDYDEAEALLEKALEL---DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 392895181  711 EIYLEEKKDKRMFAAcYRELLKVEAT-PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKD 770
Cdd:COG4783    80 LALLKAGDYDEALAL-LEKALKLDPEhPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 899-1136 1.99e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.84  E-value: 1.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  899 LQAELLYRRREFSQAVDICKQALAYHETDLKANLLLskifkEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEA 978
Cdd:COG3914    54 AAAAALLALAAGEAAAAAAALLLLAALLELAALLLQ-----ALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  979 AHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVtESGYNVCRGRFEwyTGDQNEALRYYSR 1058
Cdd:COG3914   129 EEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA-EALNNLGNALQD--LGRLEEAIAAYRR 205

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1059 TKDSAAGWRE---KALYYMIDICLNPDNEIIIDEnsvenpettIVEEASEQQKLAKYYLDLLGKLPTTDRFLLAQNFIRM 1135
Cdd:COG3914   206 ALELDPDNADahsNLLFALRQACDWEVYDRFEEL---------LAALARGPSELSPFALLYLPDDDPAELLALARAWAQL 276


                  .
gi 392895181 1136 H 1136
Cdd:COG3914   277 V 277
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 912-1027 2.00e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 2.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  912 QAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNT 991
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 392895181  992 NPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNP 1027
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 497-662 2.55e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.42  E-value: 2.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  497 KTLQMIYDVAPGLAHCTLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELILDRgGKITDADDALVTGLNFNf 576
Cdd:COG2956   131 EVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ-GDYEEAIAALERALEQD- 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  577 klRETSLYHLIKSKTFKKRNENDEAIKTLKMALQIprkepsknlfqpkesadTHKISVQLELIDTLQHMKRIQEAETTMT 656
Cdd:COG2956   209 --PDYLPALPRLAELYEKLGDPEEALELLRKALEL-----------------DPSDDLLLALADLLERKEGLEAALALLE 269


                  ....*.
gi 392895181  657 DALAEW 662
Cdd:COG2956   270 RQLRRH 275
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 630-933 2.90e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 2.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  630 HKISVQLELIDTLQHMKRIQEAETTMTDALAEWAGQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRI-K 708
Cdd:COG3914     3 AAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALlE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  709 MAEIYLEEKKDKRMFAACYRELLKV-EATPGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLY 787
Cdd:COG3914    83 LAALLLQALGRYEEALALYRRALALnPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  788 SKAVNFYEssmniykdknmrlklanlllklrnfekcekvlRApFERDPEpvgtetiqtYIQFLLLLAECHEMMDNVPEAM 867
Cdd:COG3914   163 EEAIAALR--------------------------------RA-LELDPD---------NAEALNNLGNALQDLGRLEEAI 200

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 392895181  868 NDFEKAKSLHSRiQDKTLTAAL--KKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLL 933
Cdd:COG3914   201 AAYRRALELDPD-NADAHSNLLfaLRQACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELL 267
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 1208-1305 5.28e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 5.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1208 WLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFELYGYMREKEQKYVEAYKMYEKAfMATKERNPGFGYKLAFTYLKA 1287
Cdd:COG4235    20 WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERA-LALDPDNPEALYLLGLAAFQQ 98

                          90
                  ....*....|....*...
gi 392895181 1288 KRLFACIETCQKVLDLNP 1305
Cdd:COG4235    99 GDYAEAIAAWQKLLALLP 116
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 927-1058 6.33e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 6.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  927 DLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELF 1006
Cdd:COG4783     3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 392895181 1007 CRNGEQNAAEKHLDRAKEVNPRCVTesgYNVCRGRFEWYTGDQNEALRYYSR 1058
Cdd:COG4783    83 LKAGDYDEALALLEKALKLDPEHPE---AYLRLARAYRALGRPDEAIAALEK 131
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 650-780 2.07e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 2.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  650 EAETTMTDALAEwagQPEQDQLVIAQAQLYLTKGHVERALGILKK---IQPGQSNFHLSrikMAEIYLEEKKDKRMFAAc 726
Cdd:COG4235     1 EAIARLRQALAA---NPNDAEGWLLLGRAYLRLGRYDEALAAYEKalrLDPDNADALLD---LAEALLAAGDTEEAEEL- 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 392895181  727 YRELLKVEAT-PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKD---VQLAEKIGEA 780
Cdd:COG4235    74 LERALALDPDnPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADapaRLLEASIAEA 131
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 732-795 2.13e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 42.69  E-value: 2.13e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392895181  732 KVEATPGS---YSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYE 795
Cdd:COG4235     9 ALAANPNDaegWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLE 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
846-1024 5.59e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 5.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  846 YIQFLLLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHE 925
Cdd:COG0457    41 DAEALYNLGLAYLRLGRYEEALADYEQA-------------LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDP 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  926 TDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVEL 1005
Cdd:COG0457   108 DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAA 187

                         170
                  ....*....|....*....
gi 392895181 1006 FCRNGEQNAAEKHLDRAKE 1024
Cdd:COG0457   188 LALAAAEVLLALLLALEQA 206
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 657-802 9.81e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 9.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  657 DALAEWAGQPEQDQLVIAQAQLYLTKGHVERALGILKKIQPGQSNFHLSRIKMAEIYLEEKKDKRMFAACYRELLKVEAT 736
Cdd:COG5010     7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 392895181  737 -PGSYSLLGDAFMKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYK 802
Cdd:COG5010    87 nPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 885-1027 1.10e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  885 LTAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEA 964
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392895181  965 NSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNP 1027
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 506-800 2.08e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.82  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  506 APGLAHctLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADA-HILRAELILDRGgkitDADDALVTgLNfnfKLRETSLY 584
Cdd:COG3071    48 APLLAY--LLAARAAQALGDYERRDEYLAQALELAPEAELAvLLTRAELLLDQG----QAEQALAT-LE---ALRAGAPR 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  585 H----LIKSKTFKKRNENDEAIKTLkmalqiPRKEPSKNLfqPKESADTHKISVQLELIDtlQHMKRiqeaettmTDALA 660
Cdd:COG3071   118 HpqvlRLLLQAYRQLGDWEELLELL------PALRKHKAL--SAEEAQALERRAYLGLLR--QAARD--------AEALK 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  661 E-WAGQPEQDQ----LVIAQAQLYLTKGHVERALGILkkiqpgqsnfhlsrikmaeiyleekkdkrmfaacyRELLKVEA 735
Cdd:COG3071   180 AlWKALPRAERrdpeLAAAYARALIALGDHDEAERLL-----------------------------------REALKRQW 224

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 392895181  736 TPGSYSLLGDAfmKVQEPEDAINFYEQALKMQSKDVQLAEKIGEAYVMAHLYSKAVNFYESSMNI 800
Cdd:COG3071   225 DPRLVRLYGRL--QGGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALAL 287
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1208-1310 2.27e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 2.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181 1208 WLMLADIYINQNKNDQAVTFLDLVFKYNCNCLKAFELYGYMREKEQKYVEAYKMYEKAfMATKERNPGFGYKLAFTYLKA 1287
Cdd:COG0457    45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKA-LELDPDDAEALYNLGLALLEL 123

                          90       100
                  ....*....|....*....|...
gi 392895181 1288 KRLFACIETCQKVLDLNPQYPKI 1310
Cdd:COG0457   124 GRYDEAIEAYERALELDPDDADA 146
TPR_12 pfam13424
Tetratricopeptide repeat;
739-803 2.82e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.82e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 392895181   739 SYSLLGDAFMKVQEPEDAINFYEQALKMQSK--------DVQLAEKIGEAYVMAHLYSKAVNFYESSMNIYKD 803
Cdd:pfam13424    5 ALNNLAAVLRRLGRYDEALELLEKALEIARRllgpdhplTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
955-1074 3.79e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.76  E-value: 3.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  955 IQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQHWHALSRVVELFCRNGEQNAAEKHLDRAKEVNPRCVTesG 1034
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAE--A 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 392895181 1035 YNvCRGRFEWYTGDQNEALRYYSRT----KDSAAGWREKALYYM 1074
Cdd:COG0457    79 LN-NLGLALQALGRYEEALEDYDKAleldPDDAEALYNLGLALL 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 850-995 6.28e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 6.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  850 LLLLAECHEMMDNVPEAMNDFEKAkslhsriqdktltAALKKEGARICNLQAELLYRRREFSQAVDICKQALAYHETDLK 929
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKA-------------LELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPE 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392895181  930 ANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEAAHASTSYTTLLNTNPQH 995
Cdd:COG4783    74 ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 502-704 6.46e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 40.75  E-value: 6.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  502 IYDVAPGLAHCTLQLARNSYLCSNTNAAEKWIEKVLDKDDSLADAHILRAELiLDRGGKITDADDALVTGLNFNFKLRET 581
Cdd:COG3914    70 AAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNL-LLALGRLEEALAALRRALALNPDFAEA 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  582 slyHLIKSKTFKKRNENDEAIKTLKMALQIprkepsknlfqpkesaDTHKISVQLELIDTLQHMKRIQEAETTMTDALAE 661
Cdd:COG3914   149 ---YLNLGEALRRLGRLEEAIAALRRALEL----------------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALEL 209

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 392895181  662 wagQPEQDQLVIAQAQLYLTKG------HVERALGILKKIQPGQSNFHL 704
Cdd:COG3914   210 ---DPDNADAHSNLLFALRQACdwevydRFEELLAALARGPSELSPFAL 255
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 899-993 9.32e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 9.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392895181  899 LQAELLYRRREFSQAVDICKQALAYHETDLKANLLLSKIFKEENKWTLVLQPCQTVIQVDPHNDEANSILADFYYIRSEA 978
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDY 101

                          90
                  ....*....|....*
gi 392895181  979 AHASTSYTTLLNTNP 993
Cdd:COG4235   102 AEAIAAWQKLLALLP 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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