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Conserved domains on  [gi|71993338|ref|NP_001021714|]
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Cell division cycle protein 27 homolog [Caenorhabditis elegans]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 12124078)

tetratricopeptide repeat (TPR) protein with an ANAPC3 (anaphase-promoting complex, subunit 3) domain, such as human cell division cycle protein 27 homolog and Dictyostelium discoideum anaphase-promoting complex/cyclosome (APC/C) subunit 3

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  16896351|21153002|10517866|30708253
SCOP:  4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 545-778 2.51e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 112.13  E-value: 2.51e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESrERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG2956  27 AIDLLEEALELDP-ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRS 704
Cdd:COG2956 106 DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA 185

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71993338 705 RLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPRGEQNITDSNVINREE 778
Cdd:COG2956 186 ELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 38-118 5.50e-15

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


:

Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 70.75  E-value: 5.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338    38 KCYAFDDAIFLAELHYETDkSNNSESLLLYADCLYRANKKEECYGLLSSVKLSGARL--FYLLARVSYDLNKIDDCRGAL 115
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAE-PESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLgcRYLFAQCLLKLKKYDEALDAL 79


                  ...
gi 71993338   116 FEH 118
Cdd:pfam12895  80 GKA 82
Metaviral_G super family cl26626
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
 185-329 5.63e-04

Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.


The actual alignment was detected with superfamily member pfam09595:

Pssm-ID: 462833 [Multi-domain]  Cd Length: 183  Bit Score: 41.86  E-value: 5.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   185 HTFEKHHRKSNGLYLDSPASSLKSETPSPNVPGPSsssaastaepsrleSSVRRSTRGTIASANR-----ETRNTTSNIT 259
Cdd:pfam09595  59 HPEQEHHENPPLNEAAKEAPSESEDAPDIDPNNQH--------------PSQDRSEAPPLEPAAKtkpseHEPANPPDAS 124

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71993338   260 PRQSTPGSTPSrinptAPRKSS--RISEMTTRRTESSVTGSRSSlfteperphTRATHSSRNRANAALNSDT 329
Cdd:pfam09595 125 NRLSPPDASTA-----AIREARtfRKPSTGKRNNPSSAQSDQSP---------PRANHEAIGRANPFAMSST 182
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 545-778 2.51e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 112.13  E-value: 2.51e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESrERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG2956  27 AIDLLEEALELDP-ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRS 704
Cdd:COG2956 106 DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA 185

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71993338 705 RLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPRGEQNITDSNVINREE 778
Cdd:COG2956 186 ELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 38-118 5.50e-15

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 70.75  E-value: 5.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338    38 KCYAFDDAIFLAELHYETDkSNNSESLLLYADCLYRANKKEECYGLLSSVKLSGARL--FYLLARVSYDLNKIDDCRGAL 115
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAE-PESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLgcRYLFAQCLLKLKKYDEALDAL 79


                  ...
gi 71993338   116 FEH 118
Cdd:pfam12895  80 GKA 82
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 572-762 1.03e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 78.20  E-value: 1.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   572 SLQRQHTQAIECMERAIQLD-KRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRdyRAWYGLGLVHLKKEQNL--TA 648
Cdd:TIGR02917 101 LLQGKFQQVLDELPGKTLLDdEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPR--SLYAKLGLAQLALAENRfdEA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   649 LTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSP 728
Cdd:TIGR02917 179 RALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAP 258

                         170       180       190
                  ....*....|....*....|....*....|....
gi 71993338   729 DEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAP 292
Metaviral_G pfam09595
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
 185-329 5.63e-04

Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.


Pssm-ID: 462833 [Multi-domain]  Cd Length: 183  Bit Score: 41.86  E-value: 5.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   185 HTFEKHHRKSNGLYLDSPASSLKSETPSPNVPGPSsssaastaepsrleSSVRRSTRGTIASANR-----ETRNTTSNIT 259
Cdd:pfam09595  59 HPEQEHHENPPLNEAAKEAPSESEDAPDIDPNNQH--------------PSQDRSEAPPLEPAAKtkpseHEPANPPDAS 124

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71993338   260 PRQSTPGSTPSrinptAPRKSS--RISEMTTRRTESSVTGSRSSlfteperphTRATHSSRNRANAALNSDT 329
Cdd:pfam09595 125 NRLSPPDASTA-----AIREARtfRKPSTGKRNNPSSAQSDQSP---------PRANHEAIGRANPFAMSST 182
TPR_1 pfam00515
Tetratricopeptide repeat;
561-594 7.56e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.56e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 71993338   561 PQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRF 594
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 545-778 2.51e-27

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 112.13  E-value: 2.51e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESrERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG2956  27 AIDLLEEALELDP-ETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRS 704
Cdd:COG2956 106 DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLA 185

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71993338 705 RLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPRGEQNITDSNVINREE 778
Cdd:COG2956 186 ELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKE 259
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
559-783 3.86e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 110.87  E-value: 3.86e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 559 ERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLV 638
Cdd:COG0457   6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 639 HLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLV 718
Cdd:COG0457  86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71993338 719 ELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPRGEQNITDSNVINREEYEDDE 783
Cdd:COG0457 166 LLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALL 230
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
588-784 2.40e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.78  E-value: 2.40e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 588 IQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLC 667
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 668 TLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNT 747
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                       170       180       190
                ....*....|....*....|....*....|....*..
gi 71993338 748 HLALLNYSWAAELDPRGEQNITDSNVINREEYEDDEY 784
Cdd:COG0457 161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLL 197
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 563-763 7.03e-23

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.42  E-value: 7.03e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 563 SWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKK 642
Cdd:COG2956  10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 643 EQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDK 722
Cdd:COG2956  90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 71993338 723 LKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPR 763
Cdd:COG2956 170 ALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPD 210
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 594-763 3.09e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 88.63  E-value: 3.09e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 594 FAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIE 673
Cdd:COG2956   7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 674 QQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLN 753
Cdd:COG2956  87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                       170
                ....*....|
gi 71993338 754 YSWAAELDPR 763
Cdd:COG2956 167 LEKALKLDPD 176
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 574-748 3.80e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 92.36  E-value: 3.80e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 574 QRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQ 653
Cdd:COG3914  91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALR 170

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 654 KAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEA-- 731
Cdd:COG3914 171 RALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSel 250

                       170       180
                ....*....|....*....|....*..
gi 71993338 732 --FIFH--------LLARVHRRMGNTH 748
Cdd:COG3914 251 spFALLylpdddpaELLALARAWAQLV 277
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 627-763 8.38e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 80.62  E-value: 8.38e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 627 RDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRL 706
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 71993338 707 LFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPR 763
Cdd:COG4783  82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 539-745 1.46e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 87.36  E-value: 1.46e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 539 HLQDTHALSALSQILTTESRERPQSWCAAGNCFSLQRQHT-----QAIECMERAIQLDKRFAYAYTLLGHELIVQDELDK 613
Cdd:COG3914  17 LLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAaallaLAAGEAAAAAAALLLLAALLELAALLLQALGRYEE 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 614 AAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLN 693
Cdd:COG3914  97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 71993338 694 PLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMG 745
Cdd:COG3914 177 PDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQAC 228
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 562-694 5.87e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 78.31  E-value: 5.87e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 562 QSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLK 641
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 71993338 642 KEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNP 694
Cdd:COG4783  85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 595-730 1.20e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 77.15  E-value: 1.20e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 595 AYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQ 674
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 71993338 675 QRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDE 730
Cdd:COG4783  84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 545-751 1.87e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.16  E-value: 1.87e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESrERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG2956  61 AIRIHQKLLERDP-DRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRS 704
Cdd:COG2956 140 GPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLA 219

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 71993338 705 RLLFEANRNEECLVELDKLKASSPDEAFIFhLLARVHRRMGNTHLAL 751
Cdd:COG2956 220 ELYEKLGDPEEALELLRKALELDPSDDLLL-ALADLLERKEGLEAAL 265
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 579-706 8.71e-16

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 74.66  E-value: 8.71e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 579 QAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNI 658
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 71993338 659 NPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRL 706
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 38-118 5.50e-15

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 70.75  E-value: 5.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338    38 KCYAFDDAIFLAELHYETDkSNNSESLLLYADCLYRANKKEECYGLLSSVKLSGARL--FYLLARVSYDLNKIDDCRGAL 115
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAE-PESPEDAYLLAQCLFLNGQYKRAYELLRKAKLNGSSLgcRYLFAQCLLKLKKYDEALDAL 79


                  ...
gi 71993338   116 FEH 118
Cdd:pfam12895  80 GKA 82
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 572-762 1.03e-14

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 78.20  E-value: 1.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   572 SLQRQHTQAIECMERAIQLD-KRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRdyRAWYGLGLVHLKKEQNL--TA 648
Cdd:TIGR02917 101 LLQGKFQQVLDELPGKTLLDdEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPR--SLYAKLGLAQLALAENRfdEA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   649 LTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSP 728
Cdd:TIGR02917 179 RALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAP 258

                         170       180       190
                  ....*....|....*....|....*....|....
gi 71993338   729 DEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAP 292
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 613-731 2.30e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 70.42  E-value: 2.30e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 613 KAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTL 692
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 71993338 693 NPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEA 731
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 545-674 2.44e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 70.42  E-value: 2.44e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESrERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG4235   2 AIARLRQALAANP-NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQ 674
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 574-762 4.54e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.80  E-value: 4.54e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 574 QRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAW------YGLGLVHLKKEQNLT 647
Cdd:COG3914  17 LLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLllaallELAALLLQALGRYEE 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 648 ALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASS 727
Cdd:COG3914  97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                       170       180       190
                ....*....|....*....|....*....|....*
gi 71993338 728 PDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:COG3914 177 PDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 545-662 1.01e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 1.01e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTtESRERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG4783  23 AEALLEKALE-LDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKL 101

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTN 662
Cdd:COG4783 102 DPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
570-664 4.71e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.50  E-value: 4.71e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 570 CFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAgSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTAL 649
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|....*
gi 71993338 650 TNIQKAVNINPTNRA 664
Cdd:COG3063  80 AYLERALELDPSALR 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 566-660 2.12e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 62.67  E-value: 2.12e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 566 AAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQN 645
Cdd:COG5010  59 PSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138

                        90
                ....*....|....*
gi 71993338 646 LTALTNIQKAVNINP 660
Cdd:COG5010 139 DEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
608-694 2.22e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.57  E-value: 2.22e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 608 QDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALtNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLID 687
Cdd:COG3063   5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                ....*..
gi 71993338 688 RALTLNP 694
Cdd:COG3063  84 RALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 571-775 3.60e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.03  E-value: 3.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   571 FSLQRQHTQ-AIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTAL 649
Cdd:TIGR02917 542 LYLRTGNEEeAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   650 TNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPD 729
Cdd:TIGR02917 622 SSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPK 701

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 71993338   730 EAFIFHLLARVHRRMGNTHLALLNYSWAAELDPrgeqniTDSNVIN 775
Cdd:TIGR02917 702 AALGFELEGDLYLRQKDYPAAIQAYRKALKRAP------SSQNAIK 741
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 585-695 6.54e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.51  E-value: 6.54e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 585 ERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRA 664
Cdd:COG5010  44 AAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123

                        90       100       110
                ....*....|....*....|....*....|.
gi 71993338 665 MLCTLSQIEQQRGQIDTALVLIDRALTLNPL 695
Cdd:COG5010 124 AYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 598-762 1.19e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 65.10  E-value: 1.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   598 YTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRG 677
Cdd:TIGR02917 468 HNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG 547

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   678 QIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWA 757
Cdd:TIGR02917 548 NEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKL 627


                  ....*
gi 71993338   758 AELDP 762
Cdd:TIGR02917 628 LALQP 632
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 595-763 5.95e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 5.95e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 595 AYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNIN---------PTNRAM 665
Cdd:COG3914   1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGeaaaaaaalLLLAAL 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 666 LCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMG 745
Cdd:COG3914  81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLG 160

                       170
                ....*....|....*...
gi 71993338 746 NTHLALLNYSWAAELDPR 763
Cdd:COG3914 161 RLEEAIAALRRALELDPD 178
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
568-690 6.42e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 59.93  E-value: 6.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 568 GNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLT 647
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71993338 648 ALTNIQKAVNINPTN--RAMLCTLSQIE------------------QQRGQIDTALVLIDRAL 690
Cdd:COG4785 160 AIADLEKALELDPNDpeRALWLYLAERKldpekalallledwatayLLQGDTEEARELFKLAL 222
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
672-763 2.93e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.79  E-value: 2.93e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 672 IEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLvELDKLKASSPDEAFIFHLLARVHRRMGNTHLAL 751
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|..
gi 71993338 752 LNYSWAAELDPR 763
Cdd:COG3063  80 AYLERALELDPS 91
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
571-757 4.84e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.23  E-value: 4.84e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 571 FSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLsPRDYRAWYGLGLVHLKKEQNLTALT 650
Cdd:COG4785  16 AAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALAL-PDLAQLYYERGVAYDSLGDYDLAIA 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 651 NIQKAVNINPT------NRAMLCTlsqieqQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLK 724
Cdd:COG4785  95 DFDQALELDPDlaeaynNRGLAYL------LLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKAL 168

                       170       180       190
                ....*....|....*....|....*....|....
gi 71993338 725 ASSPDEAFIFHLLARVHRRMG-NTHLALLNYSWA 757
Cdd:COG4785 169 ELDPNDPERALWLYLAERKLDpEKALALLLEDWA 202
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 545-762 1.06e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.94  E-value: 1.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   545 ALSALSQILTTESRERPqSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:TIGR02917 178 ARALIDEVLTADPGNVD-ALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKK 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRS 704
Cdd:TIGR02917 257 APNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLA 336

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 71993338   705 RLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:TIGR02917 337 SIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDP 394
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 648-776 1.92e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 1.92e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 648 ALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASS 727
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 71993338 728 PDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPRGEQNITDSNVINR 776
Cdd:COG4235  82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 621-762 9.14e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 52.27  E-value: 9.14e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 621 ALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACR 700
Cdd:COG5010  12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELY 91

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71993338 701 FNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:COG5010  92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
638-729 1.22e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.17  E-value: 1.22e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 638 VHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLiDRALTLNPLDVACRFNRSRLLFEANRNEECL 717
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|..
gi 71993338 718 VELDKLKASSPD 729
Cdd:COG3063  80 AYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 586-728 1.33e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.88  E-value: 1.33e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 586 RAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAM 665
Cdd:COG5010  11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71993338 666 LCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKASSP 728
Cdd:COG5010  91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 543-762 2.80e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.32  E-value: 2.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   543 THALSALSQILTTESRErPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSAL 622
Cdd:TIGR02917 346 DEAIATLSPALGLDPDD-PAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAA 424

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   623 LLSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFN 702
Cdd:TIGR02917 425 QLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAAN 504

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   703 RSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:TIGR02917 505 LARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNP 564
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 545-762 1.77e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 1.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   545 ALSALSQiLTTESRERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:TIGR02917 450 ALAAAKK-LEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTI 528

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVACRFNRS 704
Cdd:TIGR02917 529 DPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLG 608

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 71993338   705 RLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDP 762
Cdd:TIGR02917 609 RAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKP 666
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 599-725 3.55e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 3.55e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   599 TLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGLGLVHLKKEqNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQ 678
Cdd:TIGR02917 774 TALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELK-DPRALEYAERALKLAPNIPAILDTLGWLLVEKGE 852

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 71993338   679 IDTALVLIDRALTLNPLDVACRFNRSRLLFEANRNEECLVELDKLKA 725
Cdd:TIGR02917 853 ADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKLLN 899
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 636-751 4.82e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 46.06  E-value: 4.82e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 636 GLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNP-LDVACRFNRSRLLFEANRNE 714
Cdd:COG3071  23 GLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPeAELAVLLTRAELLLDQGQAE 102

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 71993338 715 ECLVELDKLKASSPDEAFIFHLLARVHRRMGNTHLAL 751
Cdd:COG3071 103 QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELL 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 545-626 6.66e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 6.66e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESRErPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG5010  73 SLALLEQALQLDPNN-PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151


                ..
gi 71993338 625 SP 626
Cdd:COG5010 152 SP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
545-690 7.87e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 7.87e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 545 ALSALSQILTTESrERPQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLL 624
Cdd:COG0457  95 ALEDYDKALELDP-DDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 71993338 625 SPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRAL 690
Cdd:COG0457 174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239
Metaviral_G pfam09595
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
 185-329 5.63e-04

Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.


Pssm-ID: 462833 [Multi-domain]  Cd Length: 183  Bit Score: 41.86  E-value: 5.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   185 HTFEKHHRKSNGLYLDSPASSLKSETPSPNVPGPSsssaastaepsrleSSVRRSTRGTIASANR-----ETRNTTSNIT 259
Cdd:pfam09595  59 HPEQEHHENPPLNEAAKEAPSESEDAPDIDPNNQH--------------PSQDRSEAPPLEPAAKtkpseHEPANPPDAS 124

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71993338   260 PRQSTPGSTPSrinptAPRKSS--RISEMTTRRTESSVTGSRSSlfteperphTRATHSSRNRANAALNSDT 329
Cdd:pfam09595 125 NRLSPPDASTA-----AIREARtfRKPSTGKRNNPSSAQSDQSP---------PRANHEAIGRANPFAMSST 182
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 545-745 1.07e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 42.66  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   545 ALSALSQILTTESRERPQSwCAAGNCFSLQRQHTQAiECMERAIQLDKRFAYAYTLLGH---ELIVQDELDKAAGSFRSA 621
Cdd:TIGR00990 243 AESKAKEILETKPENLPSV-TFVGNYLQSFRPKPRP-AGLEDSNELDEETGNGQLQLGLkspESKADESYEEAARAFEKA 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   622 LL---LSPRDYRAWYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPLDVA 698
Cdd:TIGR00990 321 LDlgkLGEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPD 400

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 71993338   699 CRFNRSRLLFEANRNEECLVELDKLKASSPDEAFIFHLLARVHRRMG 745
Cdd:TIGR00990 401 IYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEG 447
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 574-664 1.45e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 1.45e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 574 QRQHTQAIECMERAIQL---DKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYR---AWYGLGLVHLKKEQNLT 647
Cdd:COG1729   6 AGDYDEAIAAFKAFLKRypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDK 85

                        90
                ....*....|....*..
gi 71993338 648 ALTNIQKAVNINPTNRA 664
Cdd:COG1729  86 ARATLEELIKKYPDSEA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 632-766 2.26e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 2.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338 632 WYGLGLVHLKKEQNLTALTNIQKAVNINPTNRAMLCTLSQIEQQRGQIDtalvlidRALTLnpldvacrfnrsrllfean 711
Cdd:COG2956  11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYD-------RAIRI------------------- 64

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 71993338 712 rneeclveLDKLKASSPDEAFIFHLLARVHRRMGNTHLALLNYSWAAELDPRGEQ 766
Cdd:COG2956  65 --------HQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAE 111
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 579-783 3.41e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 3.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   579 QAIECMERAIQLDKRFAYAYTLLGHELIVQDELDKAAGSFRSALLLSPRDYRAWYGL-GLVHLKKEQNLTALTNIQKAVN 657
Cdd:TIGR02917  74 AAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAAELLALrGLAYLGLGQLELAQKSYEQALA 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71993338   658 INPTNRAMLCTLSQIEQQRGQIDTALVLIDRALTLNPldvacrfnrsrllfeanrneeclveldklkasSPDEAFIfhLL 737
Cdd:TIGR02917 154 IDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADP--------------------------------GNVDALL--LK 199

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 71993338   738 ARVHRRMGNTHLALLNYSWAAELDPRGEQNITDSNVINREEYEDDE 783
Cdd:TIGR02917 200 GDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245
TPR_1 pfam00515
Tetratricopeptide repeat;
561-594 7.56e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.56e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 71993338   561 PQSWCAAGNCFSLQRQHTQAIECMERAIQLDKRF 594
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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